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1

Tomešová, Tereza. "Autonomní jednokanálový deinterleaving." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-445470.

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This thesis deals with an autonomous single-channel deinterleaving. An autonomous single-channel deinterleaving is a separation of the received sequence of impulses from more than one emitter to sequences of impulses from one emitter without a human assistance. Methods used for deinterleaving could be divided into single-parameter and multiple-parameter methods according to the number of parameters used for separation. This thesis primarily deals with multi-parameter methods. As appropriate methods for an autonomous single-channel deinterleaving DBSCAN and variational bayes methods were chosen
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Kadlčík, Libor. "Implementace rekonstrukčních metod pro čtení čárového kódu." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220266.

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Bar code stores information in the form of series of bars and gaps with various widths, and therefore can be considered as an example of bilevel (square) signal. Magnetic bar codes are created by applying slightly ferromagnetic material to a substrate. Sensing is done by reading oscillator, whose frequency is modulated by presence of the mentioned ferromagnetic material. Signal from the oscillator is then subjected to frequency demodulation. Due to temperature drift of the reading oscillator, the demodulated signal is accompanied by DC drift. Method for removal of the drift is introduced. Also
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Klimeš, Martin. "Metody hodnocení variant outsourcingu IS/ICT." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-15554.

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The thesis "Methods to Assess IS/ICT Outsourcing Models" focuses mainly on an assessment and selection process of suitable IS/ICT outsourcing models. First, IS/ICT outsourcing concept is explained and its advantages as well as disadvantages are described. Second, IS/ICT outsourcing models (primarily classified by outsourcing subject) and their characteristics are described. Third, existing methods to assess and subsequently select suitable IS/ICT outsourcing models are analysed. Main goal of the thesis is to confront the existing methods with a process used in real-life IS/ICT outsourcing proj
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Fülöp, Tibor. "Výpočetní metody pro anotační analýzy genetických variací." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2015. http://www.nusl.cz/ntk/nusl-234900.

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Analýza a interpretace variací DNA je důležité pro zkoumání genetického pozadí dědičnosti, nemocí a jiných fenotypových rysů. Tato práce stručně úvadí oblasti molekulární biologie a základních principů genetiky, popisuje metody pro anotační analýzy genetických variací, genomové asociační studie a metody pro analýzy obohacení s jejich implementací. V rámci této práce jsme představili nový webový nástroj Varanto, který může být použit k anotaci, vizualizaci a analýze genetických variací. Může být použit k analýze obohacení anotací pomocí hypergeometrického testu pro danou množinu variací. Varant
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Hrnčířová, Barbora. "Praktické využití metod vícekriteriálního rozhodování v aplikaci na výběr stavebního materiálu." Master's thesis, Vysoká škola ekonomická v Praze, 2007. http://www.nusl.cz/ntk/nusl-1259.

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Předmětem diplomové práce je výběr vhodného materiálu na stavbu. Metodika je založena na vícekriteriálním hodnocení variant. Při výběru materiálu na stavbu musíme vzít v potaz velké množství kritérií, jedná se jak o kritéria ekonomická, jako je cena, tak především o kritéria technická. Cílem diplomové práce je jednak samotný výběr vhodného materiálu, jednak ověření možnosti použití metod vícekriteriálního hodnocení variant v praxi a případně odhalení jejich nevýhod a nedostatků při srovnání výsledků jednotlivých metod. Práce také ukazuje, že jednodušší modely vícekriteriálního hodnocení varian
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Buchta, Vladislav. "Rám přívěsu Variant pro přepravu kabelových cívek." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-229240.

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Thesis deals with the truck frame VARIANT 252. The main task is to analyze weighting states, setting the values for weigting states. Strength control of the frame by using the Finite Element Method (FEM). And each subsequent frame adjustments based on the results of FEM. Part of this thesis is also the drawing documentation provided a modified frame assembly and each modified components.
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Felcman, Adam. "Value at Risk: Historická simulace, variančně kovarianční metoda a Monte Carlo simulace." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-124888.

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The diploma thesis "Value at Risk: Historical simulation, variance covariance method and Monte Carlo" aims to value the risk which real bond portfolio bears. The thesis is decomposed into two major chapters: Theoretical and Practical chapters. The first one speaks about VaR and conditional VaR theory including their advantages and disadvantages. Moreover, there are described three basic methods to calculate VaR and CVaR with adjustments to each method in order to increase the reliability of results. The last chapter brings results of VaR and CVaR computation. Many graphs, tables and images are
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Lang, Rostislav. "Návrh a výpočet membránové konstrukce zastřešení stadionu." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2013. http://www.nusl.cz/ntk/nusl-226463.

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This diploma thesis deals with problem of design and calculation of membrane structure of stadium roof. This is a complex engineering problem, which includes many partial problems: finding of initial form of membrane, statically and architecturally suitable arrangement of catenaries, economical solution of boundary conditions (foundations). All components affect each other and cannot be dealt without mutual coordination. It always greatly depends on the experience and intuition of engineer who design such structure. Task which cannot be resolved according to the theory of the first order. Equi
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Blažek, Jaroslav. "Rám přívěsu Variant 200 pro přepravu kabelových cívek." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229427.

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The aim of this thesis is an analysis of the construction of a cable trailer VARIANT 200. For the calculation of load states was used a multi body system in program MSC.ADAMS. The results from these calculations were used as lifting conditions for strength control with finite element method (FEM). All acquired results were analysed and according to them changes were made to the frame construction. Part of this thesis contains drawings documenting the above mentioned changes.
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Alshahrani, Mohammed Nasser D. "Statistical methods for rare variant association." Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/22436/.

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Deoxyribonucleic acid (DNA) sequencing allows researchers to conduct more complete assessments of low-frequency and rare genetic variants. In anticipation of the availability of next-generation sequencing data, there is increasing interest in investigating associations between complex traits and rare variants (RVs). In contrast to association studies of common variants (CVs), due to the low frequencies of RVs, common wisdom suggests that existing statistical tests for CVs might not work, motivating the recent development of several new tests that analyze RVs, most of which are based on the ide
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Gottlieb, Michael. "Text based methods for variant prioritization." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/60358.

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Despite improvements in sequencing technologies, DNA sequence variant interpretation for rare genetic diseases remains challenging. In a typical workflow for the Treatable Intellectual Disability Endeavor in B.C. (TIDE BC), a geneticist examines variant calls to establish a set of candidate variants that explain a patient's phenotype. Even with a sophisticated computation pipeline for variant prioritization, they may need to consider hundreds of variants. This typically involves literature searches on individual variants to determine how well they explain the reported phenotype, which is a tim
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Doležel, Tomáš. "Aplikace metod vícekriteriálního hodnocení variant při výběru zaměstnanců." Master's thesis, Vysoká škola ekonomická v Praze, 2007. http://www.nusl.cz/ntk/nusl-4249.

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The thesis describes the application of several methods of multicriterial evaluation of alternatives (MEoA) in various phases of the recruitment process for the position Corporate Account Manager in Telefónica O2 Czech Republic, a.s. In the first round, the group of all enrolled candidates is reduced using aspiration levels. In the second round, this narrowed down group goes through the Assessment Centre. Using other methods of MEoA, the most suitable candidate for the position is chosen.
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Vilánková, Veronika. "Implementace metod vícekriteriálního hodnocení variant v prostředí IZAR." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-72622.

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This thesis describes the implementation methods for multi-criteria evaluation into the software application. IZAR is a software product that solves decision problems. IZAR solves single and multi-criteria, continuous and discrete decision problems. This thesis describes the extension of application IZAR. Several methods of multi-criteria evaluation were added into application. Supplemented methods were chosen so that the extended applications use the most basic methods from the decision theory. Introductory part of the thesis describes the basic methods that have been implemented into IZAR. T
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Reiter, Martin. "Analýza variant paralelního provozu oblastí 110 kV Čebín a Sokolnice." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2016. http://www.nusl.cz/ntk/nusl-242133.

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The diploma thesis is focused on the analysis of parallel operation of Čebín and Sokolnice substations. Different variants of parallel operation are researched. A calculation of steady state by the iterative method is described in the theoretical part. The next part briefly mentions a short-circuit and dimensioning of conductors. The possibility of overloading of lines and transformers is discussed in the last chapter of the theoretical part. The current state of the situation is described in the practical part. Main goal of the practical part of the diploma thesis is to design a configuration
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Štolc, Zdeněk. "Metody výpočtu VaR pro tržní a kreditní rizika." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-4682.

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This thesis is focused on a theoretical explication of the basic methods of the calculation Value at Risk for the market and credit risk. For the market risk there is in detail developed the variance -- covariance method, historical simulation and Monte Carlo simulation, above all for the nonlinear portfolio. For all methods the assumptions of their applications are highlighted and the comparation of these methods is made too. For the credit risk there is made a theoretical description of CreditMetrics, CreditRisk+ and KMV models. Analytical part is concerned in the quantification of Value at
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Hesounová, Kristýna. "Volba dodavatele elektřiny pro domácnost s využitím metod operačního výzkumu." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-165323.

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Main task of the thesis, as it is clear from its name, is the application of operations research methods, which could be used for selecting suppliers of electricity for the home. In the first part of thesis the functioning of the electricity market in the Czech Republic is explained and the theoretical assumptions, which are necessary for understanding the issue is described. In the practical part of the thesis some methods of multicriteria decision making and of data envelopment analysis models are presented. The results of each method are explained in detail and they are compared with result
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Mašátová, Jana. "Výběr vhodného softwaru z pohledu vícekriteriálního rozhodování." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-72119.

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In today's world there are many different substitutes for most products and services, increasing the demands on decision-making among substitutes. In order to make a decision, it may be very helpful to use multi-criterial methods for evaluating of the options, which are available to the general public through special programs. Thank to these programs, the general public does not have to be informed in detail about multi-criterial methods and can use the convenience of multi-criteria analysis. The aim of this thesis is to describe and compare the publicly available noncommercial czech software
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Weingärtner, Jan. "Rám přívěsu Variant 350 pro přepravu kabelových cívek." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229795.

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This diploma thesis deals with the solution of the trailer frame Variant 350 for transport of cable reels. The aim of this work is to drive a dynamic simulation of a cable lift generated by the track and in specific places to find this track burdensome conditions that affect the design of the frame. According to these states gained strenght to control the finite element method, implement and then modify the design and then create construction drawings prepared.
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Slavík, Vladimír. "Praktické využití metod vícekriteriálního rozhodování pro zhodnocení obchodních řetězců, kategorie sýry, v České republice." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-3999.

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The subject of diploma thesis is the evaluation of commercial chains, cheese category, in Czech Republic. The methodology is based on the multicriteria rating of alternatives. In the evaluation of commercial chains may take into account the large number of criteria are used, here are 26, which evaluates 14 alternatives (stores). To evaluate the commercial chains are used preferences of general public and experts. The main objective of the diploma thesis is to determine which store is the best for customers (general public) and for professionals, and then to compare the results.Secondary object
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Vondra, Pavel. "Aplikace vícekriteriálního rozhodování ve výrobním podniku." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-4989.

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The target of this thesis is to derermine the quality of the aluminium base alloy and size of aluminium plates used for mountain bike equipment. Furthermore the thesis assigns one provider of this material for Shaman Racing company. There were chosen methods of multicriteria evaluation of alternatives to fulfill the target. These methods are ORESTE, TOPSIS and ELECTRE I. The thesis also proves the possibilities of practical application of determined methods and analyzes possible problems that could occur during handling the input data and process of selecting the "best" alternative.
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Harwood, Kieran G. "Investigation into heuristic methods of solving time variant Vehicle Routing Problems." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/49087/.

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Traditionally, Vehicle Routing Problems (VRPs) are modelled with fixed traversal times. The amount of time it takes to drive from one end of a road to the other is unchanged throughout the day. Nearly always, the reality of the situation that is being modelled is very different, with road speeds varying heavily, especially with “rush hour" traffic. Modelling VRPs with time varying congestion means that even slight changes early in a vehicle tour can have major knock-on effects that are hard to predict. Recalculating the total traversal time of vehicles whenever their tours are changed drastica
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Vařbuchtová, Marie. "Hodnocení krajů z pohledu vícekriteriálního rozhodování." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-10402.

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This diploma thesis as is mentioned on its title, deals with confrontation of the single territories of the Czech Republic. Plentitude of data was gathered together in other to make this camparison. These data were chosen with regard to the real--life decisions. Multicriteria decision making methods were used as an instrument for comparison making.
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Trappe, Kathrin [Verfasser]. "Computational Methods for Integrative Structural Variant Analysis Across Species Boundaries / Kathrin Trappe." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1176705679/34.

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Guan, Ting. "Novel Statistical Methods for Multiple-variant Genetic Association Studies with Related Individuals." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/96243.

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Genetic association studies usually include related individuals. Meanwhile, high-throughput sequencing technologies produce data of multiple genetic variants. Due to linkage disequilibrium (LD) and familial relatedness, the genotype data from such studies often carries complex correlations. Moreover, missing values in genotype usually lead to loss of power in genetic association tests. Also, repeated measurements of phenotype and dynamic covariates from longitudinal studies bring in more opportunities but also challenges in the discovery of disease-related genetic factors. This dissertation fo
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Kánová, Eliška. "Zhodnocení běžných účtů metodami operačního výzkumu." Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-194229.

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The aim of this diploma thesis is a selection of the best current account. This thesis describes how the bank system functions in the Czech Republic. The characteristics of the banking institutions which provide current accounts and the characteristics of the compared current accounts are presented in this thesis. The Monte Carlo method and the methods multi-criteria assessment of variants are described theoretically. The selection is based on the methods of the operational research. The first part of the practical chapter focuses on the Monte Carlo method which selects the best account by cha
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Godočíková, Anna. "Postavenie Všeobecnej zdravotnej poisťovne v systéme českých zdravotných poisťovní s využitím metód viackriteriálneho hodnotenia variant." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-15761.

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The main goal of diploma thesis is the evaluation of the position of Všeobecná zdravotní pojišťovna in the system of czech health insurance companies by application of multiple criteria decision making methods. Health insurance companies are compared by provided benefits. Analysis is concentrated on three groups : the general public, women and men.
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Jiroutová, Aneta. "Analýza hypermarketů vybraného řetězce v kategorii kosmetiky s pomocí metod operačního výzkumu." Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-194719.

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The topic of this diploma thesis is the application of certain operation research methods on a practical example. The main objective is to evaluate and compare hypermarkets of selected retail company on the basis of data from cosmetics department for the year 2013. In the thesis are firstly described theoretical assumptions necessary for understanding the decision theory and DEA models, next part is then focused on selected company and its history, current market position and the different types of store formats. Following practical part shows the application of multicriteria evaluation method
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Tang, Man. "Statistical methods for variant discovery and functional genomic analysis using next-generation sequencing data." Diss., Virginia Tech, 2020. http://hdl.handle.net/10919/104039.

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The development of high-throughput next-generation sequencing (NGS) techniques produces massive amount of data, allowing the identification of biomarkers in early disease diagnosis and driving the transformation of most disciplines in biology and medicine. A greater concentration is needed in developing novel, powerful, and efficient tools for NGS data analysis. This dissertation focuses on modeling ``omics'' data in various NGS applications with a primary goal of developing novel statistical methods to identify sequence variants, find transcription factor (TF) binding patterns, and decode the
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Jirousková, Nikola. "Výběr klientů společnosti." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-193446.

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This thesis describes the issue of selecting of the company's clients Fragile media s. r. o. The company looks at the financial benefits and time. The target of this thesis is to determine what kind of clients brings to Fragile media s. r. o. the greatest benefit. This issue I will discuss in the practical part of this thesis by using multi-criteria decision making. In next step I will deal with what effect will have other methods of estimating weights of the criteria for the results.
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Bergman, Olivia. "Konsten att bestämma π genom slumpen". Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-68423.

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Syftet med detta arbete var att jämföra olika stokastiska processer som generar π, de olika modellerna som  studerades var modeller baserades på Buffons-, Buffon-Laplaces- och kasta pil-problem och förutom att lösa respektive problem så undersöktes bland annat om det gick att skatta π med motsvarande problem i högre dimensioner.   Innan problemen undersöktes fick läsaren en bakgrund med nödvändiga definitioner och satser inom sannolikhetsteorin, där bland annat Kolmogorovs axiomsystem, fördelningars täthetsfunktion, väntevärde och varians presenterades, men också olika definitioner av konverge
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Pokorný, Tomáš. "Využití teorie fuzzy množin a jejich rozšíření v metodě TOPSIS." Master's thesis, Vysoká škola ekonomická v Praze, 2016. http://www.nusl.cz/ntk/nusl-205686.

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This master's thesis deals with extensions of TOPSIS method, which is one of methods for multi-criteria evaluation of alternatives. These extensions use theory of fuzzy sets (FS) and their futher extensions to interval-valued (IVFS), intuitionistic (IFS) and hesitant (HFS) fuzzy sets and their combinations (IVIFS, IVIHFS). Significant part of this thesis explains the principle of fuzzy sets and their generalizations. Descriptions of operators for aggregations of grades of membership has very important role here. Next, very short description of multi-criteria evaluation problems and detailed de
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Zhang, Fan. "Statistical Methods for Characterizing Genomic Heterogeneity in Mixed Samples." Digital WPI, 2016. https://digitalcommons.wpi.edu/etd-dissertations/419.

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"Recently, sequencing technologies have generated massive and heterogeneous data sets. However, interpretation of these data sets is a major barrier to understand genomic heterogeneity in complex diseases. In this dissertation, we develop a Bayesian statistical method for single nucleotide level analysis and a global optimization method for gene expression level analysis to characterize genomic heterogeneity in mixed samples. The detection of rare single nucleotide variants (SNVs) is important for understanding genetic heterogeneity using next-generation sequencing (NGS) data. Various compu
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Řezníček, Josef. "Aplikace a porovnání metod vícekriteriálního hodnocení při mezipodnikovém srovnávání." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-8181.

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The target of this thesis is to compare suitable application methods at intercompany comparison. Used methods are divided into three sections. In the first part, the multiple criteria decision methods are described. Within this part, common used methods (method of simple order, method of standard variables, method of distance from virtual subject) and more advanced methods taught in the class of Theory of decision (WSA, Topsis, ELECTRE III, Mappac and other) are described. As part of these methods the determination preferences are defined. Further Data envelope analyses are introduced. The las
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Andrews, Peter T. J. "Design reuse in a CAD environment." Thesis, Brunel University, 1999. http://bura.brunel.ac.uk/handle/2438/5086.

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For many companies, design related information mainly exists as rooms of paper-based archives, typically in the form of manufacturing drawings and technical specifications. This 'static' information cannot be easily reused. The work presented in this thesis proposes a methodology to ease this problem. It defines and implements a computer-based design tool that will enable existing design families to be transformed into 'dynamic' CAD-based models for the Conceptual, Embodiment and Detailed stages of the design process. Two novel concepts are proposed here, i) the use of a Function Means Tree to
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Köchert, Karl. "Development of a method to assess EAAT1 transcription levels in Alzheimer's disease." Master's thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2008/1596/.

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Zur Zeit leiden ca. 24 Millionen Menschen auf der ganzen Welt unter Demenz, Alzheimer macht dabei 50-60% aller Demenzfälle aus. Da der Anteil der Bevölkerung, der an Demenz leidet, proportional zum Alter zunimmt und der Anteil älterer Menschen in der Gesellschaft von Jahr zu Jahr steigt, wird Alzheimer immer mehr zu einem ernstzunehmenden, gesellschaftlichen Problem. Zum Stand der heutigen Forschung ist es etabliert, dass die Aminosäure Glutamat - quantitativ einer der wichtigsten Neurotransmitter im Zentralen Nervensystem (ZNS) - toxische Konzentrationen erreichen kann wenn sie - im Zuge der
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Klasová, Petra. "Aplikace metod vícekriteriálního rozhodování při volbě financování nemovitosti." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-162821.

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The most important factor which people consider when deciding whether to invest in their own housing is the price of the selected real estate and the way of its financing. The aim of this thesis is to attempt to compile a complete list of products which are suitable for real estate financing, using methods of multicriteria decision in evaluating these products and examination of the appropriateness of the methods. The objective is to theoretically describe and practically analyse not only primary mortgage loans, but also ordinary and bridging loans from buildings savings. The core of this thes
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Hindalong, Emily Ann. "A study of methods for learning phylogenies of cancer cell populations from binary single nucleotide variant profiles." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54550.

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An accurate phylogeny of a cancer tumour has the potential to shed light on numerous phenomena, such as key oncogenetic events, relationships between clones, and evolutionary responses to treatment. Most work in cancer phylogenetics to-date relies on bulk tissue data, which can resolve only a few genotypes unambiguously. Meanwhile, single-cell technologies have considerably improved our ability to resolve intra-tumour heterogeneity. Furthermore, most cancer phylogenetic methods use classical approaches, such as Neighbor-Joining, which put all extant species on the leaves of the phylogenetic tr
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Machková, Radka. "Hodnocení vybraných států EU." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-75293.

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This diploma thesis targets the evaluation of fifteen chosen EU countries using the methods of multicriteria decision-making. The topic is elaborated from the perspective of a student of the University of Economics, Prague, who chooses a suitable country to gain experience abroad. Students' preferences are recorded in a questionnaire and grouped using direct weights estimation method. The ORESTE, WSA, TOPSIS, PROMETHEE II and MAPPAC methods are described in the thesis and applied to the data using an add-on of Microsoft Excel -- Sanna. Since the questionnaire contains a question on the student
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Papoutsidakis, Michail G. "Modern methods for position control of systems : real-world and simulated application to a time variant pneumatic actuator." Thesis, University of the West of England, Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501091.

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The Ph.D. programme arose naturally from the fundamental questions remaining after completing MPhil research at UWR in a very similar subject area. which was in achieving effective proportional position control of a linear pneumatic actuator. There are many challenging reasons for using pneumatic systems for control in certain important potential application areas, i.e., their numerous and multiple applications in modern industry due to their extensive beneficial characteristics. The still-unsolved problem of robust long-term proportional control of pneumatic actuators keeps the continuous res
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Griffith, Malachi. "Methods for transcript variant discovery and alternative expression analysis : application to the study of fluorouracil resistance in colorectal cancer." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/18621.

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RNA transcripts are expressed from tens of thousands of loci across the human genome. Several studies have suggested that many genes are alternatively expressed to produced multiple mRNA isoforms and many of these remain undiscovered. Identifying specific isoforms associated with human diseases such as cancer has potential to lead to improved treatments. The scale and complexity of the transcriptome present significant barriers to (1) identifying isoforms and (2) applying knowledge to human disease research. Recent advances in genome-wide microarray and sequencing platforms have begun to p
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Buhescu, Razvan Mihai. "Implementation of a global router for symmetrical FPGAs based on the dual-affine variant of Karmarkar's interior-point method." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23321.

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FPGAs have been among the fastest growing segments of the semiconductor industry and this growth is expected to continue over the next several years. The complexity of FPGAs makes manual designs time consuming and error prone; design automation tools are essential to the effective use of FPGAs. Routing is one part of the design process of VLSI chips that is computational complex and hence very time consuming.<br>The arrival of the interior-point method proposed by N. Karmarkar was an important event in linear programming and several variants have been developed since then. Recent experiments i
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Celba, Šimon. "Rozhodování v malých a středních podnicích." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-259759.

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The goal of the work is the creation of a system for decision making support in the company BSL, s.r.o.. The system for the decision making is to resolve the problem with decision making in choosing personal computers for the companys partners. In the thesis a system for decision making for the company BSL is suggested, as well as its functions and the methodology it utilizes are clearly described. The abilities of the systems are introduced through realistic computations during the choice of a personal computer for individual BSL partners. The results are interpreted through a user interfac
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Antonenko, Zhanna. "Rizika použití VAR modelů při řízení portfolia." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-202134.

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The diploma thesis Risks of using VaR models for portfolio management is focused on estimation of the portfolio VaR using basic and modified methods. The goal of this thesis is to point out some weakness of the basic methods and to demonstrate the estimation of VaR using improved methods to overcome these problems. The analysis will be perform theoretically and in practice. Only market risk will be the subject of the study. Several simulation and parametric methods will be introduced.
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Borovička, Adam. "Vytváření investičního portfolia podílových fondů pomocí fuzzy metod vícekriteriálního rozhodování." Doctoral thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-199395.

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The thesis deals with investment decision making. It starts from the decision making situation about the making of an investment portfolio of the open unit trusts. The whole decision making process is described, namely the methodical approaches used in terms of the portfolio making procedure. Thus, the main part of this paper focuses on a detailed description of an algorithm of the fuzzy weight estimation method, fuzzy multiple criteria evaluation method and fuzzy multiple objective programming method. The methods are proposed on the basis of current concepts; they conclude the new ideas as we
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Szarková, Lucia. "Podnikateľské riziká v poisťovníctve a ich kvantifikácia." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-192614.

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Diploma thesis Business risks in insurance and their quantification describes the business risks to which insurance companies are exposed in their activities. Thesis is focused on market risk and quantification of market risk in insurance companies. It includes determination of the specifications for the activities of insurance companies, regulation and characteric of business risks in insurance. Large part of the thesis deals with the method of Value at Risk as a tool to measure market risk as well as individual methods to calculate it. In the conclusion, thesis describes the processes of qua
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Nachtigal, Noël Maurice. "A look-ahead variant of the Lanczos algorithm and its application to the quasi-minimal residual method for non-Hermitian linear systems." Thesis, Massachusetts Institute of Technology, 1991. http://hdl.handle.net/1721.1/13516.

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Štoll, Karel. "Stanovení hodnoty podniku ŽĎAS, a. s." Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2015. http://www.nusl.cz/ntk/nusl-225073.

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This thesis deals with the determination of the value of the joint-stock company ŽĎAS using the income approach. To determine the value of the yield method was used the DCF method in variant entity and EVA also in variant entity. The theoretical part is mainly focused on describing the procedure of determining the value of the company from the definition of the enterprise, the categories of value and purposes awards to description of methods and their specific process. The practical part is attended of determining the value of the company ŽĎAS at the level of an objective value that can be con
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Kysilko, Vít. "Optimalizace HIC kritéria při nárazu impaktorem hlavy na kapotu auta." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230463.

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Kvůli stále značnému počtu usmrcených chodců při dopravních nechodách se výrobci automobilů snaží pomocí vhodné konstrukce automobilu zmírnit následky způsobené nehodou. Při srážce impaktoru hlavy s kapotou automobilu dochází ke zpomalení impaktoru a na toto zpomalení je aplikováno HIC kitérium. HIC kritérium vyhodnocuje míru možnosti poranění hlavy při srážce. Cílem diplomové práce je výběr nejvhodnějšího časového průběhu zpomalení dětského impaktoru hlavy při srážce s kapotou automobilu Škoda Superb II z hlediska HIC kritéria a navržení konstrukčních úprav kapoty a okolních částí, které se d
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Aleckovic, Ehlimana, Linnea Andersson, Sherley Chamoun, et al. "Method Development for Determining the Stability of Heat Stable Proteins Combined with Biophysical Characterization of Human Calmodulin and the Disease Associated Variant D130G." Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-138022.

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Calmodulin is a highly conserved calcium ion binding protein expressed in all eukaryotic species. The 149 amino acid residues in the primary structure are organized in seven α helices with the highly flexible central α helix connecting the two non-cooperative domains of calmodulin. Each domain contains two EF-hand motifs to which calcium ions bind in a cooperative manner, hence the binding of four calcium ions saturate one calmodulin molecule. In the cardiovascular area calmodulin is involved in the activation of cardiac muscle contraction, and mutations that arise in the genetic sequence of t
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Gonzaga, Anderson dos Santos [UNESP]. "Resultados de existência de soluções para problemas elípticos assintoticamente lineares." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/152494.

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Submitted by Anderson dos Santos Gonzaga null (andersongonzaga25@yahoo.com.br) on 2018-01-16T17:28:55Z No. of bitstreams: 1 Gonzaga.dissertação.pdf: 1264952 bytes, checksum: e682e5fd46c5a7d68506f3f9499cded5 (MD5)<br>Approved for entry into archive by Claudia Adriana Spindola null (claudia@fct.unesp.br) on 2018-01-16T17:58:17Z (GMT) No. of bitstreams: 1 gonzaga_as_me_prud.pdf: 1264952 bytes, checksum: e682e5fd46c5a7d68506f3f9499cded5 (MD5)<br>Made available in DSpace on 2018-01-16T17:58:17Z (GMT). No. of bitstreams: 1 gonzaga_as_me_prud.pdf: 1264952 bytes, checksum: e682e5fd46c5a7d68506f3f9
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