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1

Åkesson, H. "Long-Term Clinical Results following Correction of Incompetent Superficial and Perforating Veins in Patients with Deep Venous Incompetence and Ulcers." Phlebology: The Journal of Venous Disease 8, no. 3 (1993): 128–31. http://dx.doi.org/10.1177/026835559300800310.

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Objectives: To assess the presence of venous ulcers following stripping of the saphenous vein and ligation of perforating veins in patients with deep venous incompetence. Design: Retrospective follow-up after a median of 41 months following surgery. Patients: Thirty operated limbs in 25 patients with venous ulcers, originally entering a prospective study of physiological changes following surgery for venous insufficiency. Interventions: An interview regarding absence of ulcers, expressed as a percentage of the follow-up time after surgery – the ‘ulcer-free period’. Correlation with ambulatory
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2

Lin, Yun-Nan, Tung-Ying Hsieh, Shu-Hung Huang, Chia-Ming Liu, Kao-Ping Chang, and Sin-Daw Lin. "Management of venous ulcers according to their anatomical relationship with varicose veins." Phlebology: The Journal of Venous Disease 33, no. 1 (2017): 44–52. http://dx.doi.org/10.1177/0268355516676124.

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Background Adequately excising varicose and incompetent perforating veins is necessary for reducing their recurrence rate of venous ulcer. Method In total, 66 venous ulcers (C6) in 1083 legs with primary varicose veins were managed through endoscopic-assisted surgery. In an endoscopic operative view, the nonvaricose, varicose, and incompetent perforating veins were clearly visualized and precisely dissected. The varicose and incompetent perforating veins were divided and completely excised. Result The varicose veins were traced to the base or periphery of the 55 ulcers. Moreover, 89.4% of the
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3

Gloviczki, P. "Surgical Treatment of the Superficial and Perforating Veins." Phlebology: The Journal of Venous Disease 15, no. 3-4 (2000): 131–36. http://dx.doi.org/10.1177/026835550001500309.

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Objective: To review the techniques and results of surgical treatment of the superficial and perforating veins in patients with chronic venous insufficiency. Methods: The current techniques used at the Mayo Clinic for treatment of simple varicose veins and venous ulcers are presented. Results of subfascial endoscopic perforator vein surgery (SEPS) are discussed and data from large centres are tabulated. Results are compared with those reported following non-operative management. Synthesis: High ligation and invagination stripping of the incompetent segment of the saphenous vein, with stab avul
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4

Seren, Mustafa, Mert Dumantepe, Osman Fazliogullari, and Suha Kucukaksu. "Combined treatment with endovenous laser ablation and compression therapy of incompetent perforating veins for treatment of recalcitrant venous ulcers." Phlebology: The Journal of Venous Disease 32, no. 5 (2015): 307–15. http://dx.doi.org/10.1177/0268355515594075.

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Objective Patients with healed venous ulcers often experience recurrence of ulceration, despite the use of long-term compression therapy. This study examines the effect of closing incompetent perforating veins (IPVs) on ulcer recurrence rates in patients with progressive lipodermatosclerosis and impending ulceration. Methods Patients with nonhealing venous ulcers of >2 months’ duration underwent duplex ultrasound to assess their lower extremity venous system for incompetence of superficial, perforating, and deep veins. Endovenous laser ablation (EVLA) of perforating veins was performed on p
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5

Abelyan, Gohar, Lusine Abrahamyan, and Gayane Yenokyan. "A case-control study of risk factors of chronic venous ulceration in patients with varicose veins." Phlebology: The Journal of Venous Disease 33, no. 1 (2017): 60–67. http://dx.doi.org/10.1177/0268355516687677.

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Background/objectives Venous ulcers carry psychological and high financial burden for patients, causing depression, pain, and limitation of mobility. The study aimed to identify factors associated with an increased risk of venous ulceration in patients with varicose veins in Armenia. Methods A case-control study design was utilized enrolling 80 patients in each group, who underwent varicose treatment surgery in two specialized surgical centers in Armenia during 2013–2014 years. Cases were patients with varicose veins and venous leg ulcers. Controls included patients with varicose veins but wit
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6

Erel, E., L. D. Wijesinghe, and P. T. McCollum. "Surgical Management of Leg Ulcers Associated with Pulsatile Varicose Veins and Tricuspid Regurgitation." Phlebology: The Journal of Venous Disease 15, no. 2 (2000): 84–86. http://dx.doi.org/10.1177/026835550001500209.

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Design: Case report. Setting: Vascular Surgery Department, Hull Royal Infirmary, UK. Patients: A 79-year-old man with a history of right leg ulcer and pulsatile veins. Investigations and interventions: Clinical examination revealed findings of tricuspid regurgitation. Investigations included duplex scans, CT scan, arteriography and both trans-thoracic and trans-oesophageal echocardio-graphy. These all proved inconclusive. High sapheno-femoral ligation and stripping of long saphenous vein ligation procedure resulted in healing of his ulcers within six months Conclusion: Pulsatile veins in the l
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7

Gallus, Alexander. "Early vs deferred endovenous ablation reduced time to ulcer healing in venous leg ulcers with varicose veins." Annals of Internal Medicine 169, no. 4 (2018): JC18. http://dx.doi.org/10.7326/acpjc-2018-169-4-018.

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8

Opie, J. C., T. Izdebski, D. N. Payne, and S. R. Opie. "Monocusp – novel common femoral vein monocusp surgery uncorrectable chronic venous insufficiency with aplastic/dysplastic valves." Phlebology: The Journal of Venous Disease 23, no. 4 (2008): 158–71. http://dx.doi.org/10.1258/phleb.2007.007075.

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Objective Previous reparative valvular surgical options directed at reconstructing damaged common femoral vein (CFV) valves associated with pathological chronic venous insufficiency (CVI) have not succeeded in reliably managing CVI. In consequence, venous valvuloplasty is rare and most patients are managed conservatively. As a result, monocusp surgery was identified as an optional surgical solution for this large underserved patient group. Methods Ulcer patients appear at wound clinics and often experience disappointing results. Monocusp valves were constructed utilizing viable vein wall in 14
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9

Bhavuray, Teli, Mundada Ashishkumar B., Avula Sreekant, Ganeshan Karthick, N. Naveen, and P. R. Venugopal. "To Study the Role of Skin Grafting and Superficial Varicose Vein Surgery Simultaneously In Treatment of Venous Ulcers." New Indian Journal of Surgery 9, no. 3 (2018): 291–95. http://dx.doi.org/10.21088/nijs.0976.4747.9318.8.

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10

Andrews, R. Hampton, and Robert G. Dixon. "Ambulatory Phlebectomy and Sclerotherapy as Tools for the Treatment of Varicose Veins and Telangiectasias." Seminars in Interventional Radiology 38, no. 02 (2021): 160–66. http://dx.doi.org/10.1055/s-0041-1727151.

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AbstractTreatment of chronic venous disease is a fascinating and rewarding undertaking. Once the truncal reflux is addressed, several options are available that can be used to treat the associated ulcers, varicosities, reticular veins, and telangiectasias. This review will focus on two widely employed procedures: ambulatory phlebectomy and sclerotherapy.
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11

Elmallah, Ahmed S., Yehia M. Alkhateeb, and Said I. Elmallah. "In the era of endo-venous ablation of varicose veins, is surgery still competitive?" International Surgery Journal 5, no. 12 (2018): 3904. http://dx.doi.org/10.18203/2349-2902.isj20185016.

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Background: There are different evolving minimally invasive surgical options for varicose veins (VV) treatment. This study compared Endo-venous Laser Ablation (EVLA) and foam sclerotherapy Vs high tie and multiple phlebectomy / ligation without vein stripping.Methods: 185 lower limbs with primary VV and sapheno-femoral junction (SFJ)incompetence were included. Patients were divided into two groups. Group A: 85 limbs in 78 patients (4 had chronic venous ulcers) were treated by EVLA & foam sclerotherapy under tumescent anesthesia. Group B: 100 limbs in 100 patients (5 had chronic venous ulce
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12

VIARENGO, LUIZ MARCELO AIELLO, JOÃO POTÉRIO-FILHO, GLORIA MARIA BRAGA POTÉRIO, FÁBIO HÜSEMANN MENEZES, and GUILHERME VIEIRA MEIRELLES. "Endovenous Laser Treatment for Varicose Veins in Patients with Active Ulcers." Dermatologic Surgery 33, no. 10 (2007): 1234–41. http://dx.doi.org/10.1097/00042728-200710000-00014.

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13

Pannier, F., and E. Rabe. "The Relevance of the Natural History of Varicose Veins and Refunded Care." Phlebology: The Journal of Venous Disease 27, no. 1_suppl (2012): 23–26. http://dx.doi.org/10.1258/phleb.2012.012s23.

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Chronic venous disease (CVD) is one of the most common diseases in our population. Aside from venous symptoms like heaviness and pain, which are present in about 50% of the general population, signs of CVD include varicose veins (VVs), oedema, eczema, venous eczema, hyperpigmentation, white atrophy, lipodermatosclerosis and venous ulcers. The aim of this paper is to review current literature for the relevance of natural history of VVs in refunded care. Available papers on VVs, progression of the disease and complications were reviewed. Prevalence of VVs is high with more than 20% in the genera
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14

Tazi, O., M. D. Petit, I. Lazareth, and C. Franceschi. "Traitement chirurgical hémodynamique des ulcères veineux rebelles." Journal des Maladies Vasculaires 33 (March 2008): S6—S7. http://dx.doi.org/10.1016/j.jmv.2008.01.017.

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15

Tedbirt, B., P. Carvalho, C. Boulard, A. Deschamps-Huvier, P. Courville, and P. Joly. "Syringo-fibroadénome réactionnel à des ulcères veineux." Annales de Dermatologie et de Vénéréologie 146, no. 12 (2019): A177—A178. http://dx.doi.org/10.1016/j.annder.2019.09.248.

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16

URAYAMA, Hiroshi, Shouichi KATADA, Eiji KANEHIRA, Masao TAKAHASHI, Yohu WATANABE, and Takashi IWA. "SURGICAL THERAPY OF REFRACTORY SKIN ULCERS WITH VARICOSE VEINS OF LOWER EXTREMITIES." Journal of the Japanese Practical Surgeon Society 50, no. 10 (1989): 2152–55. http://dx.doi.org/10.3919/ringe1963.50.2152.

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17

Ouvry, Pierre. "Les ulcères veineux : bilan diagnostique et options thérapeutiques." Revue Francophone de Cicatrisation 1, no. 4 (2017): 28–33. http://dx.doi.org/10.1016/s2468-9114(17)30394-8.

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18

Åkesson, H., L. Brudin, W. Cwikiel, P. Ohlin, and G. Plate. "Does the Correction of Insufficient Superficial and Perforating Veins Improve Venous Function in Patients with Deep Venous Insufficiency?" Phlebology: The Journal of Venous Disease 5, no. 2 (1990): 113–23. http://dx.doi.org/10.1177/026835559000500207.

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Thirty limbs in 25 patients with chronic deep venous insufficiency and recurrent ulceration were examined by ascending and descending contrast phlebography, occlusion plethysmography, foot volumetry and ambulatory venous pressure. Superficial venous insufficiency was surgically corrected by stripping of the saphenous vein and local excision of the varicosities (op1) in 12 limbs. Perforating venous insufficiency was then corrected by extensive subfascial ligation of perforating veins (op2) in all limbs. Venous outflow capacity, measured by occlusion plethysmography, and muscle pump function, me
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19

Lawrence, Peter F., Ali Alktaifi, David Rigberg, Brian DeRubertis, Hugh Gelabert, and Juan Carlos Jimenez. "Endovenous ablation of incompetent perforating veins is effective treatment for recalcitrant venous ulcers." Journal of Vascular Surgery 54, no. 3 (2011): 737–42. http://dx.doi.org/10.1016/j.jvs.2011.02.068.

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20

Lawrence, Peter, Ali Alktaifi, and David Rigberg. "Endovenous Ablation of Incompetent Perforator Veins Is Effective Treatment for Recalcitrant Venous Ulcers." Journal of Vascular Surgery 52, no. 2 (2010): 525. http://dx.doi.org/10.1016/j.jvs.2010.05.028.

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21

Erel, E., L. D. Wijesinghe, and P. T. McCollum. "Surgical Management of Leg Ulcers Associated with Pulsatile Varicose Veins and Tricuspid Regurgitation." Phlebology 15, no. 2 (2000): 84–86. http://dx.doi.org/10.1007/s005230070028.

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22

Partsch. "Varicose veins and chronic venous insufficiency." Vasa 38, no. 4 (2009): 293–301. http://dx.doi.org/10.1024/0301-1526.38.4.293.

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Varicose veins are a very frequent disorder with prevalence in our adult population between 14 % for large varices and 59 % for small teleangiectasias. Subjective symptoms may be very non-specific. The term “chronic venous insufficiency (CVI)” defines functional abnormalities of the venous system producing advanced symptoms like oedema, skin changes or leg ulcers. Both entities, varicose veins and CVI, may be summarized under the term “chronic venous disorders” which includes the full spectrum of morphological and functional abnormalities of the venous system. A classification system to descri
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23

Thuillier, D., O. Ganry, and C. Lok. "Facteurs pronostiques de cicatrisation des ulcères de jambe veineux." Journal des Maladies Vasculaires 34, no. 2 (2009): 96. http://dx.doi.org/10.1016/j.jmv.2008.12.056.

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24

Bachmeyer, C., A. Cazier, B. Rohaut, and Y. Turc. "Carcinome épidermoïde compliquant un ulcère veineux chronique de jambe." Annales de Dermatologie et de Vénéréologie 132, no. 6-7 (2005): 589–90. http://dx.doi.org/10.1016/s0151-9638(05)79349-2.

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25

Van Cleef, J. F. "Gel rhéoépaississant pour compresser le pansement d’un ulcère veineux." JMV-Journal de Médecine Vasculaire 45 (March 2020): S60. http://dx.doi.org/10.1016/j.jdmv.2020.01.144.

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26

Van Cleef, J. F. "Gel rhéoépaississant pour compresser le pansement d’un ulcère veineux." JMV-Journal de Médecine Vasculaire 45 (November 2020): S120—S121. http://dx.doi.org/10.1016/j.jdmv.2020.10.118.

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27

Van Cleef, J. F. "Gel rhéoépaississant pour compresser le pansement d’un ulcère veineux." JMV-Journal de Médecine Vasculaire 46, no. 5 (2021): S69—S70. http://dx.doi.org/10.1016/j.jdmv.2021.08.065.

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28

Cohen, Jacqueline M., Elie A. Akl, and Susan R. Kahn. "Systematic Review of Pharmacologic and Compression Therapies for Treatment of Post-Thrombotic Syndrome." Blood 116, no. 21 (2010): 4207. http://dx.doi.org/10.1182/blood.v116.21.4207.4207.

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Abstract Abstract 4207 Background: Post-thrombotic syndrome (PTS) is a chronic complication of deep venous thrombosis (DVT) characterized by chronic pain, swelling and other signs in the affected limb that can severely impact individuals' quality of life. There are no widely accepted treatments for PTS, although varied treatment strategies have been proposed. Objective: To systematically review evidence for the effectiveness and safety of pharmacologic and compression therapies for treatment of PTS. Methods: Randomized controlled trials (RCTs) of PTS treatments were sought in a search of PubMe
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29

Kalinin, Roman E., Igor A. Suchkov, Marina V. Laut, Nina D. Mzhavanadze, and Ivan N. Shanaev. "Varicose Veins: A Local or Systemic Hemodynamic Disorder?" Journal of Diagnostic Medical Sonography 36, no. 4 (2020): 328–34. http://dx.doi.org/10.1177/8756479320912683.

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Objective: To determine the capabilities of a sonographic examination to evaluate local and systemic hemodynamic disorders in patients with varicose disease. Materials and Methods: This study included 583 patients with varicose veins, among whom 348 had trophic disorders. All subjects underwent lower limb duplex sonography and superficial, perforator, and deep venous diameter measurements, as well as had a calculated velocity for antegrade and reflux flow. Peripheral resistive index (RI) in the arteries, accompanying perforator veins (PVs), was analyzed. In addition, echocardiography was perfo
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30

Darvall, Katy A. L., Rachel C. Sam, Donald J. Adam, Stanley H. Silverman, Christopher D. Fegan, and Andrew W. Bradbury. "Higher prevalence of thrombophilia in patients with varicose veins and venous ulcers than controls." Journal of Vascular Surgery 49, no. 5 (2009): 1235–41. http://dx.doi.org/10.1016/j.jvs.2008.12.017.

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31

Wolters, Ulrich, Thomas Schmitz-Rixen, Heide Erasmi, and John Lynch. "Endoscopic Dissection of Incompetent Perforating Veins in the Treatment of Chronic Venous Leg Ulcers." Vascular Surgery 30, no. 6 (1996): 481–87. http://dx.doi.org/10.1177/153857449603000608.

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32

Lee, Jing-Syuan, Yen-Chang Hsiao, and Cheng-Jen Chang. "Endovenous Photocoagulation Using a Diode Laser for Complicated Varicose Veins Related to Stasis Ulcers." Annals of Plastic Surgery 82 (January 2019): S103—S107. http://dx.doi.org/10.1097/sap.0000000000001726.

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33

Lawrence, Peter F., Micheal Harlander-Locke, Ali Alktaifi, et al. "RR26. The Impact of Ablation of Incompetent Veins on Ulcer Healing." Journal of Vascular Surgery 53, no. 6 (2011): 109S—110S. http://dx.doi.org/10.1016/j.jvs.2011.03.212.

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34

Benigni, Jean-Patrick. "Ulcère veineux : bandages ou bas, des indications différentes en pratique." Revue Francophone de Cicatrisation 1, no. 1 (2017): 22. http://dx.doi.org/10.1016/s2468-9114(17)30063-4.

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35

Benigni, Jean-Patrick. "Ulcère veineux : bandages ou bas, des indications différentes en pratique." Revue Francophone de Cicatrisation 1, no. 1 (2017): 28. http://dx.doi.org/10.1016/s2468-9114(17)30079-8.

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36

Huppert, L., J. L. Perrot, B. Labeille, A. C. Biron, A. Leclercq, and F. Cambazard. "Épidémiologie des ulcères veineux et de l’indice de masse corporelle." Annales de Dermatologie et de Vénéréologie 142, no. 12 (2015): S580—S581. http://dx.doi.org/10.1016/j.annder.2015.10.334.

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37

Chaby, G., P. Senet, O. Ganry, et al. "Facteurs pronostiques de cicatrisation des ulcères veineux : étude prospective multicentrique." Annales de Dermatologie et de Vénéréologie 139, no. 12 (2012): B278. http://dx.doi.org/10.1016/j.annder.2012.10.508.

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38

Ito, Takaaki, Ryuichi Kukino, Masakazu Takahara, et al. "The wound/burn guidelines - 5: Guidelines for the management of lower leg ulcers/varicose veins." Journal of Dermatology 43, no. 8 (2016): 853–68. http://dx.doi.org/10.1111/1346-8138.13286.

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39

Marston, William A. "Efficacy of endovenous ablation of the saphenous veins for prevention and healing of venous ulcers." Journal of Vascular Surgery: Venous and Lymphatic Disorders 3, no. 1 (2015): 113–16. http://dx.doi.org/10.1016/j.jvsv.2014.09.009.

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40

Mwipatayi, Bibombe P., Catherine E. Western, Jackie Wong, and Donna Angel. "Atypical leg ulcers after sclerotherapy for treatment of varicose veins: Case reports and literature review." International Journal of Surgery Case Reports 25 (2016): 161–64. http://dx.doi.org/10.1016/j.ijscr.2016.06.024.

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41

van Rij, A. M., J. Vincent, G. Hill, and G. T. Jones. "Failure of Microvenous Valves in Small Superficial Veins: A Key to the Development of Venous Ulcers." Journal of Vascular Surgery 53, no. 1 (2011): 256. http://dx.doi.org/10.1016/j.jvs.2010.11.017.

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42

Ananthakrishnan, Nilakantan, Satya Parkash, and Subendra N. Banerjee. "A new incision for subfascial ligation of perforating veins in chronic venous ulcers of the leg." American Journal of Surgery 155, no. 4 (1988): 615. http://dx.doi.org/10.1016/s0002-9610(88)80421-5.

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43

Boulenger-Vazel, A., V. Viseux, P. Schoenlaub, M. Auffret, F. Staroz, and P. Plantin. "Ulcère veineux de la main secondaire à une fistule artérioveineuse thérapeutique." Annales de Dermatologie et de Vénéréologie 132, no. 11 (2005): 887–90. http://dx.doi.org/10.1016/s0151-9638(05)79508-9.

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44

Huppert, L., J. L. Perrot, B. Labeille, A. C. Biron, A. Leclercq, and F. Cambazard. "Épidémiologie des ulcères non veineux et de l’indice de masse corporelle." Annales de Dermatologie et de Vénéréologie 142, no. 12 (2015): S584—S585. http://dx.doi.org/10.1016/j.annder.2015.10.342.

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45

Burnand, K. G., S. Powell, C. Bishop, M. Stacey, and T. Pulvertaft. "Effect of Paroven on Skin Oxygenation in Patients with Varicose Veins." Phlebology: The Journal of Venous Disease 4, no. 1 (1989): 15–22. http://dx.doi.org/10.1177/026835558900400104.

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A double blind placebo-controlled clinical trial was undertaken to investigate the effect of 500 mg bd of Paroven taken for four weeks on the tissue oxygenation, ankle oedema and calf pump function of 48 patients with chronic venous disease. There was no evidence that Paroven reduced ankle swelling or improved calf pump function, but it did cause a significant improvement in transcutaneous oxygen levels measured in the calf skin of the ulcer hearing area ( p = 0.026) which was confirmed when the oxygen levels of the active and placebo treated groups were compared at the end of four weeks treat
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46

Casian, D., E. Gutsu, and V. Culiuc. "Surgical treatment of severe chronic venous insufficiency caused by pulsatile varicose veins in a patient with tricuspid regurgitation." Phlebology: The Journal of Venous Disease 24, no. 2 (2009): 79–81. http://dx.doi.org/10.1258/phleb.2008.008043.

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A case of severe chronic venous insufficiency caused by pulsatile varicose veins in a 46-year-old man with tricuspid regurgitation is presented. Active venous leg ulcer complicated with recurrent venous bleeding and inefficacy of conservative management serve as indications for surgical treatment. This case demonstrates the possibility of radical surgical correction of pathological venous reflux by means of saphenofemoral ligation, foam sclerotherapy and subfascial endoscopic perforator surgery.
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DE WAARD, MARIEKE M., and DAAN J. DER KINDEREN. "Duplex Ultrasonography–Guided Foam Sclerotherapy of Incompetent Perforator Veins in a Patient with Bilateral Venous Leg Ulcers." Dermatologic Surgery 31, no. 5 (2005): 580–83. http://dx.doi.org/10.1097/00042728-200505000-00018.

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48

Waard, Marieke M., and Daan J. Kinderen. "Duplex Ultrasonography-Guided Foam Sclerotherapy of Incompetent Perforator Veins in a Patient with Bilateral Venous Leg Ulcers." Dermatologic Surgery 31, no. 5 (2006): 580–83. http://dx.doi.org/10.1111/j.1524-4725.2005.31167.

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49

Holmes, Chris E., Nadia M. Bambace, Patricia Lewis, Peter Callas, and Mary Cushman. "Effectiveness of a Short Course of Complex Lymphedema Therapy or Graduated Compression Stocking Therapy In the Treatment of Post-Thrombotic Syndrome (PTS): A Randomized Control Trial." Blood 116, no. 21 (2010): 1087. http://dx.doi.org/10.1182/blood.v116.21.1087.1087.

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Abstract Abstract 1087 Background: Investigations of treatment options for established PTS are limited. Graduated compression stocking therapy (GCS) is often used in clinical practice despite limited research on effectiveness. We postulated that the venous hypertension seen in PTS leads to lymphatic overload and secondary lymphedema. Therefore, in patients with established PTS, we compared the efficacy of GCS alone to complex lymphedema therapy, a treatment that includes compression stocking use, exercise, patient education, skin care and manual lymphatic drainage. Methods: In an investigator-
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SHIRAKATA, Shuji, Satoshi NIU, Satoru OKUMURA, et al. "CLINICAL EVALUATION OF OPERATIVE TREATMENT FOR INCURABLE VENOUS ULCER FOLLOWING PRIMARY VARICOSE VEINS." Journal of the Japanese Practical Surgeon Society 51, no. 6 (1990): 1200–1204. http://dx.doi.org/10.3919/ringe1963.51.1200.

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