Thematische Bibliographien / Wine as medicine / Dissertationen
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Dissertationen zum Thema „Wine as medicine“

Autor: Grafiati
Veröffentlicht am 4. Juni 2021
Zuletzt aktualisiert am 20. Februar 2023

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1

Mårtensson, Ellinor. "Foaming in Apple Wine." Thesis, Linnaeus University, School of Natural Sciences, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-8354.

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<p>At Kiviks Musteri AB, situated in the southeast part of Scania, a wide variety of products based on fruits and berries, are produced. One of these products is base apple wine, which is used for the production of cider and mulled wine and also is sold to other producers of cider. A foaming problem has occurred at some customers when the cider is bottled, and this problem has been traced to the base wine. The aim of this paper is to investigate what causes the foaming and how the foaming is affected by the clarifying agents used during the production of the wine. An investigation whether sili
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2

Lamont, Kim. "Delineation of the Cardioprotective Agents found in red wine." Master's thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/3415.

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Secondary leach concentrate (SLC) is an important bleed stream for minor elements from Anglo Platinum's Base Metal Refinery (BMR) which produces copper nickel and cobalt sulphate. It contains mainly sulphur, iron jarosites, unleached base metals and platinum group metals (PGMs), which makes the treatment of SLC necessary. The SLC is currently toll-refined at Umicore's Hoboken smelter and refinery to recover revenue from entrapped valuable metals. This method of treatment results in excessively high costs due to high transport and toll refining expenses as well as penalties. Thus, an in-house m
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3

Blackhurst, Diane Mary. "Potential health benefits of antioxidant effects of wine on lipids." Doctoral thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/3363.

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Includes bibliographical references.<br>The consumption of wine dates back to the Stone Age, but its potential health benefits only really began to make an impact after the French Paradox was postulated by Renaud and de Lorgeril in the 1990s. Their observations indicated that moderate consumption of red wine may have health benefits. Research since then has shown that wine, in particular red wine, is a source of a large number of different polyphenolic compounds that have antioxidant activity. The finding that the consumption of red wine might have a beneficial health effect was very appealing
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4

Burns, Jennifer. "Phenolic antioxidants in red wine : content and activity." Thesis, University of Glasgow, 2000. http://theses.gla.ac.uk/3534/.

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Sensitive and selective methods were applied to the analysis of two batches of bottled wines. The relationship between the antioxidant activity, based on the reduction in Fremy's radical, vasodilation activity (batch 1 only), and phenolic content was investigated. Wines were selected to provide a range of origins, grape varieties and vinification methods. Batch 1 wines were sourced mainly from the Old World, while those in batch II were predominantly from the New World. The total phenolic content was determined by the Folin-Ciocalteu colorimetric assay and by the cumulative measurements obtain
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5

Norrie, Philip Anthony, University of Western Sydney, College of Health and Science, and School of Medicine. "Wine and health through the ages with special reference to Australia." THESIS_CHS_MED_Norrie_P.xml, 2005. http://handle.uws.edu.au:8081/1959.7/709.

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The use of wine as a medicine is not a new idea, but one that has been rediscovered and given credibility due to current research findings. This research examines the use of wine as a medicine in the past and currently. The whole question of wine and health is put into a more balanced and proper perspective, instead of the ill-informed, negative anti-alcohol view. The aim of the thesis is to document the history of the uses of wine as a medicine, particularly in Australia. The author uses a social ecology framework,which is concerned with the interrelationships between the domains of the perso
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Benhameid, Osama Saleh. "Myocardial revascularization using Omentum graft "Old wine in a new bottle"." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81267.

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Background. Therapeutic angiogenesis in cardiovascular disease aims at improving myocardial function by increasing blood flow to ischemic myocardium that is not amenable to traditional forms of revascularization. This study hypothesizes that using the Omental graft to wrap the ischemic heart will lead to formation of multiple collateral anastomoses between surrounding systemic arteries and the coronary arteriolar system of right and left coronary arteries.<br>Results. Left ventricular end diastolic pressure was reduced in the group treated with revascularized Omental graft compared to v
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7

Diaba-Nuhoho, Patrick. "Potential cardioprotective effect of chronic, moderate consumption of reduced-alcohol wine in a rat model of pulmonary hypertension." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29320.

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Background: Pulmonary arterial hypertension (PAH) is a severe disease which leads to right ventricular (RV) dysfunction and possibly death. The pathophysiological process of PAH remains unclear but oxidative stress is thought to contribute to arterial and ventricular dysfunction. Red wine has powerful antioxidant properties and is cardioprotective. However, side effects of alcohol may limit the use of wine as a therapeutic agent. The aim of this study was to test whether reduced-alcohol red wine (RARW) or regular red wine (RW) consumption would limit monocrotaline (MCT)-induced PAH in rats.
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8

Norrie, Philip Anthony. "Wine and health through the ages with special reference to Australia." Thesis, View thesis, 2005. http://handle.uws.edu.au:8081/1959.7/709.

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The use of wine as a medicine is not a new idea, but one that has been rediscovered and given credibility due to current research findings. This research examines the use of wine as a medicine in the past and currently. The whole question of wine and health is put into a more balanced and proper perspective, instead of the ill-informed, negative anti-alcohol view. The aim of the thesis is to document the history of the uses of wine as a medicine, particularly in Australia. The author uses a social ecology framework,which is concerned with the interrelationships between the domains of the perso
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9

Dlamini, Lindizwe. "Exploring the cardioprotective effect of synthetic wine in Long Evans rats." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15763.

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[No copyright notice] Background: Moderate and chronic consumption of red wine protects against cardiovascular disease. Wine is a complex matrix containing multiple molecules whose concentrations can vary from one bottle to another. Therefore, the delineation of the putative cardioprotective components in wine such as alcohol, resveratrol and melatonin is very challenging when using commercially available red wine. Aim: We aimed to use synthetic wine, whose composition is well characterized, to explore whether the presence of alcohol, resveratrol and melatonin (as found in commercial wines) c
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10

Partington, Lee Ian. "Molecular wire based bio-electrochemical sensing systems." Thesis, University of Hull, 2016. http://hydra.hull.ac.uk/resources/hull:15133.

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This thesis aims to develop rapid, quantitative point of care sensing systems that exploit molecular wire platforms to enable the electrochemical detection of multiple target biomarkers, thereby empowering new technologies for the diagnosis of various medical conditions. Accordingly, the first chapter provides an overview of clinically important biomarkers for pregnancy and cardiovascular disease. The second chapter of this thesis details the electrochemical concepts underpinning subsequent chapters, with the third chapter providing an experimental overview. The first two research chapters dev
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11

Ayati, Marzieh. "Algorithms to Integrate Omics Data for Personalized Medicine." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1527679638507616.

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12

Yeoh, Chit Cheng. "Molecular gene expression and genome wide profiling in tamoxifen-resistant breast cancer." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/370.

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Oestrogen receptor positive (ER+) breast cancers (BC) are heterogeneous in both their clinical behaviour and response to therapy. The ER and Progesterone (PgR) are currently the best predictors of response to the anti-oestrogen tamoxifen, yet up to 40% of ER+ breast cancer will relapse despite tamoxifen treatment. New prognostic biomarkers and further biological understanding of tamoxifen resistance (TR) are required. There has been an explosion of greater understanding since the arrival of cutting-edge gene and genomic profiling technology. The two major aims of this research are to develop s
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13

Raghavan, Manoj. "High-resolution genome-wide single nucleotide polymorphism mapping in acute myeloid leukaemia." Thesis, Queen Mary, University of London, 2008. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1884.

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Investigation of the genetics of acute myeloid leukaemia (AML) has revealed the underlying basis of the disease and led to targets for therapy. High-resolution single nucleotide polymorphism (SNP) arrays detected regions of loss of heterozygosity and DNA copy number changes, augmenting the results of conventional cytogenetic analysis in AML. Fifteen out of 72 (20%) primary AML samples exhibited large regions of homozygosity that could not be accounted for by visible chromosomal abnormalities in the karyotype. Further analysis confirmed that these patterns were due to partial uniparental disomy
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Heap, Graham Alastair Richard. "Assigning function to genome wide association study variants associated with complex gastrointestinal disease." Thesis, Queen Mary, University of London, 2009. http://qmro.qmul.ac.uk/xmlui/handle/123456789/535.

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The genome‐wide association study era has identified numerous loci associated with many common polygenic diseases. The next challenge is to identify the functional consequences of these variants and elicit how they impact on disease risk. Using a combination of protein based assays, large scale microarrays and high‐throughput generation sequencing platforms this thesis aims to identify the functional effects of disease loci, with particular focus on Crohn’s disease and coeliac disease, two common complex gastrointestinal diseases. Variants located within the Interleukin 23 receptor are associa
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15

Knight, Dave. "Variation in silicosis prevalence in South African gold miners : an industry-wide study." Master's thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/12412.

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Includes bibliographical references (leaves 55-65).<br>Includes abstract.<br>This study investigates the prevalence of silicosis in the South African gold mining industry. Gold mining is an important industry in South Africa, yet has been blighted by silicosis and tuberculosis in miners since its inception in 1887. There have been two previous studies conducted in black in-service miners using modern epidemiologic methods that found high prevalences of silicosis .The objectives of our study were three-fold. Firstly, to determine silicosis prevalence stratified by certain variables. Secondly, t
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16

Waldron, Joseph Alexander. "The role of the exoribonuclease Pacman/Xrn1 in wing development in Drosophila." Thesis, University of Brighton, 2014. https://research.brighton.ac.uk/en/studentTheses/6bd7b8c8-9448-4af2-b99f-aadf2e60c91b.

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RNA stability plays a critical role in the control of gene regulation by determining the levels of mRNA that can be translated into protein. The aim of this thesis is to investigate the role of the exoribonuclease Pacman in regulating gene expression during wing development in Drosophila melanogaster. Pacman is the only known cytoplasmic exoribonuclease which degrades RNA in a 5’‐3’ direction and is highly conserved across all eukaryotes.
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17

Welton, William E. "The impact of differences in market structure on community-wide Medicare expenditures." Ann Arbor, Mich. : University of Michigan, 1999. http://books.google.com/books?id=YC9YAAAAMAAJ.

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18

Patel, Riyaz. "Beyond genome wide discovery : an exploration of novel genetic variants for coronary heart disease." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/38470/.

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Recent developments spurred on by the Human Genome Project have for the first time permitted genome wide association studies leading to identification of multiple novel variants for complex diseases. This thesis consists of a series of studies exploring recent genetic findings for coronary heart disease (CHD) within the broader context of the promises of the genomic era that new findings would ultimately lead to 1) Identification of new disease mechanisms 2) Permit genotype based risk prediction and 3) Promote development of novel and targeted therapies based on genotype. We sought to address
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19

Duong, Cuong V. "Investigation of the pituitary epigenome : a genome-wide analysis of changes associated with sporadic tumours." Thesis, Keele University, 2014. http://eprints.keele.ac.uk/625/.

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Pituitary tumours harbour epigenetic aberrations; however, characterisation of these aberrations, on a genome-wide basis, is hampered by their infrequent occurrence and their small size. To overcome the constraint of limited tissue, whole genome amplification of sodium bisulphite converted DNA was employed and provided a consistent 25-fold amplification from individual samples. This material was used in a genome-wide analysis the DNA methylation of 27,578 CpG sites for each of the major adenoma subtypes. In a discovery cohort, on the basis of stringent criteria, pyrosequencing validated 12 of
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20

Martínez, García Fernando. "Elucidating the genetic susceptibility of hypertension associated microalbuminuria: genome wide scan." Doctoral thesis, Universitat de València, 2010. http://hdl.handle.net/10803/39085.

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Objective: To identify genetic susceptibility variants for hypertension associated microalbuminuria. Methods: The study design was a nested case-control genetic association study. Three hundred and three patients were selected from one prospective cohort recruited in the hypertension clinic of two different hospitals with the objective of identify clinical factors associated with microalbuminuria. All the patients were less than 50y, hypertensive grade I and naïve regarding to the treatment at the time of the recruitment. Cases were those who developed microalbuminuria (UAE>=30 mg/day) during
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21

Alsanosi, Safaa Mohammed M. "Blood pressure-lowering agents response : a systematic review and genome wide study." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8100/.

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In spite of the vast amount of evidence on the benefits of blood pressure (BP) lowering that has accumulated to date, hypertension (HTN) remains the leading risk factor for disease and disability worldwide. Since the first BP-lowering agents became available in the 1950s, their effects have been tested thoroughly by means of the best evidence-providing approach, namely, large randomised controlled trials (RCTs). In the same way, the pharmacogenomics of HTN have the potential to identify genetic biomarkers that predict the response of BP-lowering agents through genome-wide association studies (
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22

Sandling, Johanna K. "Genetic Analyses of Multiple Sclerosis and Systemic Lupus Erythematosus : From Single Markers to Genome-Wide Data." Doctoral thesis, Uppsala universitet, Molekylär medicin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-117776.

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In autoimmune diseases an individual’s immune system becomes targeted at the body’s own healthy cells. The aim of this thesis was to identify genetic risk factors for the two autoimmune diseases multiple sclerosis (MS) and systemic lupus erythematosus (SLE). In Study I, we found that genetic variation in the interferon regulatory factor 5 gene (IRF5), previously shown to be associated with SLE, rheumatoid arthritis and inflammatory bowel diseases, was associated also with MS. An insertion/deletion polymorphism in the first intron of IRF5 is as a good functional candidate for this association.
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23

Jetha, Arif. "Genome wide analysis of the response of human beta-cells to islet isolation and «in vitro» culture." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97157.

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The biggest challenge to islet transplantation is preserving cell mass and function. It is known that the stresses encountered during islet isolation have deleterious effects on beta-cell physiology. The nature of these effects, however, are incompletely known, partly due to the heterogeneity of islet preparations. Using a combination of laser capture microdissection and microarray technology, we therefore sought to determine the beta-cell specific events that occur as a result of islet isolation and in vitro culture. Our data shows that islet isolation and in vitro culture induce a large infl
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Fleming, Michael. "Using Scotland-wide record linkage to investigate the educational and health outcomes of children treated for chronic conditions." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8594/.

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Objectives: This study linked Scottish education data to a number of administrative health datasets to explore associations between childhood chronic ill health and subsequent educational and health outcomes. Chronic conditions investigated were diabetes, asthma, epilepsy, attention deficit hyperactivity disorder (ADHD) and depression. Educational outcomes were number of days absent from school, number of school exclusions, special educational need (SEN), academic attainment and unemployment. Health outcomes were all-cause and cause-specific hospital admission, total number of hospital admissi
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Tahrani, Ahmad [Verfasser], and Michael [Akademischer Betreuer] Wink. "Mass Spectrometric Approaches in Profiling and Monitoring Bioreactivity of Polyphenols in Medicinal Plants / Ahmad Tahrani ; Betreuer: Michael Wink." Heidelberg : Universitätsbibliothek Heidelberg, 2011. http://d-nb.info/1179783018/34.

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Gentles, Jeremy A. "Reducing Injuries is NOT Enough – It Also Helps to Win." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/3983.

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27

Hillman, Timothy R. "Microstructural information beyond the resolution limit : studies in two coherent, wide-field biomedical imaging systems." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0085.

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28

Pira, Rahim S. "Supporting asynchronous telemedicine : electronic mail vs. the world wide web vs. replicated databases /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0007/MQ42422.pdf.

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29

Veronin, Michael A. "The Validity of Health Claims on the World Wide Web: A Case Study of the Herbal Remedy Opuntia." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2441/.

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The World Wide Web has become a significant source of medical information for the public, but there is concern that much of the information is inaccurate, misleading, and unsupported by scientific evidence. This study analyzes the validity of health claims on the World Wide Web for the herbal Opuntia using an evidence-based approach, and supports the observation that individuals must critically assess health information in this relatively new medium of communication. A systematic search by means of nine search engines and online resources of Web sites relating to herbal remedies was conduct
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30

Wallerman, Ola. "Genome-Wide Studies of Transcriptional Regulation in Mammalian Cells." Doctoral thesis, Uppsala universitet, Medicinsk genetik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-132882.

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The key to the complexity of higher organisms lies not in the number of protein coding genes they carry, but rather in the intrinsic complexity of the gene regulatory networks. The major effectors of transcriptional regulation are proteins called transcription factors, and in this thesis four papers describing genome-wide studies of seven such factors are presented, together with studies on components of the chromatin and transcriptome. In Paper I, we optimized a large-scale in vivo method, ChIP-chip, to study protein – DNA interactions using microarrays. The metabolic-disease related transcri
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Choudhry, Hani. "Genome-wide analysis of the hypoxic breast cancer transcriptome using next generation sequencing." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:9a66b553-a66c-4164-a854-5881be65ca45.

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Hypoxia pathways are associated with the pathogenesis of both ischaemic and neoplastic diseases. In response to hypoxia the transcription factor hypoxia‐inducible factor (HIF) induces the expression of hundreds of genes with diverse functions. These enable cells to adapt to low oxygen availability. To date, pan-genomic analyses of these transcriptional responses have focussed on protein-coding genes and microRNAs. However, the role of other classes of non-coding RNAs, in particular lncRNAs, in the hypoxia response is largely uncharacterised. My thesis aimed at improving understanding of the tr
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32

Diehl, K., T. Görig, Joel J. Hillhouse, J. L. Stapleton, R. Greinert, and S. S. Schneider. "Wie Plausibel Ist Die Erfassung Von Bräunungssucht? – Ein Multimethodischer Ansatz Zur Evaluation Eines Neuen Instruments." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/2782.

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Einleitung: Ultraviolette (UV) Strahlung – sei sie natürlich oder künstlich – kann zu Hautkrebs führen. In Verbindung mit Solarien, einer Hauptquelle künstlicher UV-Strahlung, wird häufig auf die Möglichkeit der Entstehung einer Bräunungssucht (oft auch „Tanorexie“) hingewiesen. Bisherige Instrumente zum Screening auf eine solche Bräunungssucht ergaben sich jedoch als nicht valide. Aus diesem Grund war es unser Ziel, ein in den USA neu entwickeltes Instrument, den Behavioral Addiction Indoor Tanning Screener (BAITS), auf Validität und Reliabilität zu testen. Methodik: Der BAITS ist ein kurzes
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33

Cardona-Morrell, Magnolia. "Evaluation of a Community-wide Diabetes Prevention Program." Phd thesis, University of Sydney, 2011. http://hdl.handle.net/2123/8349.

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This thesis is an evaluation of the effectiveness of a community-wide diabetes prevention program conducted in three Divisions of General Practice in Sydney, Australia. The aims were to assess whether translation of diabetes prevention programs was feasible in real-life settings and whether results achieved were comparable with those of randomised trials on which this intervention was based. Its primary goals were to assess whether the lifestyle intervention could increase participation in moderate-to-vigorous physical activity to 210 minutes per week, reduce total fat and saturated fat consum
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Aragam, Nagesh Ramarao. "Genome-Wide Association Analysis of Major Depressive Disorder and Its Related Phenotypes." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/1368.

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Major Depressive Disorder (MDD) is a complex and chronic disease that ranks fourth as cause of disability worldwide. Thirteen to 14 million adults in the U.S. are believed to have MDD and an estimated 75% attempt suicide making MDD a major public health problem. Recently several genome-wide association (GWA) studies of MDD have been reported; however, few GWA studies focus on the analysis for MDD related phenotypes such as neuroticism and age at onset of MDD. The purpose of this study is to determine risk factors for MDD, identify genome-wide genetic variants affecting neuroticism and age at o
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Janes, Jennifer Gail. "THE ROLES OF ORTHOPAEDIC PATHOLOGY AND GENETIC DETERMINANTS IN EQUINE CERVICAL STENOTIC MYELOPATHY." UKnowledge, 2014. http://uknowledge.uky.edu/gluck_etds/16.

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Cervical stenotic myelopathy (CSM) is an important musculoskeletal and neurologic disease of the horse. Clinical disease occurs due to malformations of the vertebrae in the neck causing stenosis of the cervical vertebral canal and subsequent spinal cord compression. The disease is multifactorial in nature, therefore a clearer understanding of the etiology and pathogenesis of CSM will allow for improved management and therapeutic practices. This thesis examines issues of equine CSM diagnosis, skeletal tissue pathology, and inherited genetic determinants utilizing advances in biomedical imaging
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Tsuchiya, Mio. "Attitudes toward and current status of disclosure of secondary findings from next-generation sequencing: a nation-wide survey of clinical genetics professionals in Japan." Kyoto University, 2021. http://hdl.handle.net/2433/261616.

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Gaubatz, Breanna M. "EQUINE PROTOZOAL MYELOENCEPHALITIS: INVESTIGATION OF GENETIC SUSCEPTIBILITY AND ASSESSMENT OF AN EQUINE INFECTION METHOD." UKnowledge, 2013. http://uknowledge.uky.edu/gluck_etds/8.

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Equine protozoal myeloencephalitis (EPM) is a progressive neurological disease of horses caused by Sarcocystis neurona. Two projects were conducted to identify factors involved in the development of EPM. The first study explored a possible genetic susceptibility to EPM by attempting a genome-wide association study (GWAS) on formalin-fixed, paraffin-embedded (FFPE) tissue from 24 definitively-positive EPM horses. DNA extracted from tissues older than 14 months was inadequate for SNP analysis on the Illumina Equine SNP50 BeadChip probably due to degradation and formalin cross-linking. Results we
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Godeiro, José Renato Gurgel. "Reação tecidual induzida pelos fios de quitosana e náilon em ratas (Rattus norvegicus)." Universidade Federal Rural do Semi-Árido, 2013. http://bdtd.ufersa.edu.br:80/tede/handle/tede/339.

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Made available in DSpace on 2016-08-15T20:31:11Z (GMT). No. of bitstreams: 1 JoseRGG_DISSERT.pdf: 1559519 bytes, checksum: d95e795ac3354fb18dac771769a8ef30 (MD5) Previous issue date: 2013-11-18<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Chitosan is a natural biopolymer that has large portfolio of structural applications with potential mechanical modifications to generate new properties, functions and specially applications in the biomedical field. This work evaluates the induced tissue reaction between chitosan and nylon sutures used on the skin and subcutaneously, aft
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Costa, Claudio Giulliano Alves da. "Desenvolvimento e avaliação tecnologica de um sistema de prontuario eletronico do paciente, baseado nos paradigmas da World Wide Web e da engenharia de software." [s.n.], 2001. http://repositorio.unicamp.br/jspui/handle/REPOSIP/260174.

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Orientadores : Renato Marcos Endrizzi Sabbatini, Antonio Augusto Fasolo Quevedo<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação<br>Made available in DSpace on 2018-07-28T23:08:39Z (GMT). No. of bitstreams: 1 Costa_ClaudioGiullianoAlvesda_M.pdf: 6728949 bytes, checksum: a5fa3741ef6958743b2b9364dbead8a9 (MD5) Previous issue date: 2001<br>Mestrado
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Motallebipour, Mehdi. "Genetic and Genomic Analysis of Transcriptional Regulation in Human Cells." Doctoral thesis, Uppsala universitet, Institutionen för genetik och patologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9407.

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There are around 20.000 genes in the human genome all of which could potentially be expressed. However, it is obvious that not all of them can be active at the same time. Thus, there is a need for coordination achieved through the regulation of transcription. Transcriptional regulation is a crucial multi-component process involving genetic and epigenetic factors, which determine when and how genes are expressed. The aim of this thesis was to study two of these components, the transcription factors and the DNA sequence elements with which they interact. In papers I and II, we tried to character
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Padilla, Carmenita C. "High school counselor knowledge of NCAA regulations for prospective student-athlete transition to college." Scholarly Commons, 2015. https://scholarlycommons.pacific.edu/uop_etds/308.

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This descriptive study examines whether high school counselors are equipped to advise potential recruits on new NCAA academic eligibility regulations. It highlights the NCAA’s new Division I academic eligibility regulations in effect for current seniors in high school (entering collegiate class of 2016) and gives an overview of academic rule changes within the national governing body. The enhanced academic eligibility rules increase minimum GPA and test score as well as mandates strict core course requirements, prioritizing the role of a high school counselor in the entire process. The study w
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Bazzocco, Sarah. "Identification of novel therapeutic targets and tumor suppressor genes in colon cancer using genome-wide high‐throughput approaches." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/350805.

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Colorectal cancer is a disease caused by genetic and epigenetic changes. Inactivation of tumor suppressor genes and activation of oncogenes are key landmarks in tumor progression. However, the list of tumor suppressor genes and oncogenes is far from complete, even in the case of the tumor types that are best characterized, such as colorectal cancer. Colorectal cancer is the second most frequent cause of cancer-related death in the Western world and is a serious health issue for the European Union. Patients having stage III or IV cancer undergo surgery followed by chemotherapy. However, the cli
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Vieira, Anderson Roberto Assunção. "Distúrbios de comportamento, desgaste anormal dos dentes incisivos e cólica em eqüinos estabulados no 1º regimento de cavalaria de guardas, Exército Brasileiro, Brasília- DF." Universidade Federal de Viçosa, 2006. http://locus.ufv.br/handle/123456789/5111.

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Made available in DSpace on 2015-03-26T13:47:07Z (GMT). No. of bitstreams: 1 texto completo.pdf: 487807 bytes, checksum: 3b38b9ece555d67e478d2c80b4328f96 (MD5) Previous issue date: 2006-09-25<br>There is much debate over the possible causes of the behavioral problems of horses; stable stress is among the most significant. Nevertheless, given the large number of variables related to these abnormal behaviors, all conclusions reached until today remain questionable. Furthermore, it is also possible that the real determining factor of these behavioral problems is simply the incapacity of horses
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Meyers, Jacquelyn. "Elucidating Genetic and Environmental Influences on Alcohol-Related Phenotypes." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2830.

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Decades of work has led researchers to believe that risk for complex behavioral phenotypes, such as alcohol use disorders, is likely influenced by multiple genes of small effect acting in conjunction with each other and the environment. Currently, the field of psychiatric genetics is developing methodologies for the identification of genetic risk variants that predispose individuals to the development of complex behavioral disorders. Several challenges related to the complex and polygenic nature of these phenotypes, must be considered. This dissertation study attempts to address these importan
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Magalhães, Lucas Vilas Bôas 1979. "Aplicação do método Crônica Médica e Oficina Diagnóstica para educação médica via web." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312814.

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Orientador: Li Li Min<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-25T05:25:03Z (GMT). No. of bitstreams: 1 Magalhaes_LucasVilasBoas_D.pdf: 7733145 bytes, checksum: 027b6d317458988a3459061c3791fe4f (MD5) Previous issue date: 2014<br>Resumo: A educação médica via web (EMVW) em Ambientes Virtuais de Aprendizagem (AVA) vem crescendo muito, e apresenta potenciais vantagens. Os desenhos bem estruturados e comprovadamente eficazes para uso em AVA são pouco utilizados, pois, em geral, verifica-se apenas a "digitalizaçã
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Martínez, Marigorta Urko 1983. "Genetic architecture of complex disease in humans :a cross-population exploration." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/96909.

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The aetiology of common diseases is shaped by the effects of genetic and environmental factors. Big efforts have been devoted to unravel the genetic basis of disease with the hope that it will help to develop new therapeutic treatments and to achieve personalized medicine. With the development of high-throughput genotyping technologies, hundreds of association studies have described many loci associated to disease. However, the depiction of disease architecture remains incomplete. The aim of this work is to perform exhaustive comparisons across human populations to evaluate pressing questions.
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Biasci, Daniele. "Predicting prognosis in Crohn's disease." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/270034.

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Carrera, Salazar David. "Utilidad de la técnica ROLL (radioguided ocult lesion localization) en la exéresis de lesiones no palpables de mama." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/364780.

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Avaluar l'eficàcia de la localització radioguiada (ROLL) de lesions ocultes de mama (LNPM)respecte a la tècnica estàndard, l'ham quirúrgic. MÈTODE: S'han estudiat 161 dones amb LNPM, 80 marcades amb ham quirúrgic el mateix dia de la intervenció i 81 marcades amb la injecció intratumoral de 3 mCi de Tc99m Nanocoloide el dia previ a la cirurgia. Les lesions es van localitzar per ecografia o estereotàxia. Les tumorectomies es van fer , en el primer grup seguint la direcció de l'ham des de l'entrada fins la punta, i en el segon grup amb l'ajuda d'una sonda gammadetectora que indicava el lloc de
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Peterson, Roseann. "On the genetic and environmental associations between body composition, depression symptoms and smoking behavior." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2889.

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Obesity is a serious public health crisis and recent estimates of its incidence are the highest in United States history, with 35% and 17% of American adults and children affected, respectively. The clinical definition of adult obesity is operationalized as a body mass index (BMI) greater than 30 kg/m2. Although the prevalence of common obesity has increased dramatically over the past 30 years–largely thought to be due to changes in the environment, such as high calorie diets and sedentary lifestyles—twin and family studies have shown consistently that relative body weight is under considerabl
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Janunger, Tomas. "The genetic contribution to stroke in northern Sweden." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-31929.

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