Literatura académica sobre el tema "3D cell culture, spheroids"

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Artículos de revistas sobre el tema "3D cell culture, spheroids"

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Cesarz, Zoe, and Kenichi Tamama. "Spheroid Culture of Mesenchymal Stem Cells." Stem Cells International 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/9176357.

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Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or spheroids, are regarded as more physiological, and this technique has been exploited in the field of oncology, stem cell biology, and tissue engineering. Mesenchymal stem cells (MSCs) cultured in spheroids have enhanced anti-inflammatory, angiogenic, and tissue reparative/regenerative effects with improved cell survival after transplantation. Cytoskeletal reorganization and drastic changes in cell morphology in MSC spheroids indicate a major difference in mechanophysical properties compared with 2D culture. E
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Srisongkram, Tarapong, Natthida Weerapreeyakul, and Kanjana Thumanu. "Evaluation of Melanoma (SK-MEL-2) Cell Growth between Three-Dimensional (3D) and Two-Dimensional (2D) Cell Cultures with Fourier Transform Infrared (FTIR) Microspectroscopy." International Journal of Molecular Sciences 21, no. 11 (2020): 4141. http://dx.doi.org/10.3390/ijms21114141.

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Fourier transform infrared (FTIR) microspectroscopy was used to evaluate the growth of human melanoma cells (SK-MEL-2) in two-dimensional (2D) versus three-dimensional (3D) spheroid culture systems. FTIR microspectroscopy, coupled with multivariate analysis, could be used to monitor the variability of spheroid morphologies prepared from different cell densities. The characteristic shift in absorbance bands of the 2D cells were different from the spectra of cells from 3D spheroids. FTIR microspectroscopy can also be used to monitor cell death similar to fluorescence cell staining in 3D spheroid
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Lee, Dongjin, and Chaenyung Cha. "The Combined Effects of Co-Culture and Substrate Mechanics on 3D Tumor Spheroid Formation within Microgels Prepared via Flow-Focusing Microfluidic Fabrication." Pharmaceutics 10, no. 4 (2018): 229. http://dx.doi.org/10.3390/pharmaceutics10040229.

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Tumor spheroids are considered a valuable three dimensional (3D) tissue model to study various aspects of tumor physiology for biomedical applications such as tissue engineering and drug screening as well as basic scientific endeavors, as several cell types can efficiently form spheroids by themselves in both suspension and adherent cell cultures. However, it is more desirable to utilize a 3D scaffold with tunable properties to create more physiologically relevant tumor spheroids as well as optimize their formation. In this study, bioactive spherical microgels supporting 3D cell culture are fa
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Shrestha, Sunil, Vinod Kumar Reddy Lekkala, Prabha Acharya, Darshita Siddhpura, and Moo-Yeal Lee. "Recent advances in microarray 3D bioprinting for high-throughput spheroid and tissue culture and analysis." Essays in Biochemistry 65, no. 3 (2021): 481–89. http://dx.doi.org/10.1042/ebc20200150.

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Abstract Three-dimensional (3D) cell culture in vitro has proven to be more physiologically relevant than two-dimensional (2D) culture of cell monolayers, thus more predictive in assessing efficacy and toxicity of compounds. There have been several 3D cell culture techniques developed, which include spheroid and multicellular tissue cultures. Cell spheroids have been generated from single or multiple cell types cultured in ultralow attachment (ULA) well plates and hanging droplet plates. In general, cell spheroids are formed in a relatively short period of culture, in the absence of extracellu
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Kitano, Otome, and Kohji Nakazawa. "Neuronal Differentiation of NT2 Cells in Monolayer and Spheroid Cultures." MATEC Web of Conferences 333 (2021): 07008. http://dx.doi.org/10.1051/matecconf/202133307008.

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Metabolism and differentiation of cultured cells are influenced by changes in cellular morphology. In this study, we investigated the differences in cell proliferation and neuronal differentiation of NT2 cells in monolayer (2D) and spheroid (3D) cultures. In the monolayer culture, the cells adhered and extended on a tissue culture plate. For the spheroid culture, we fabricated a microwell chip comprising 195 circular microwells (600 ìm in diameter) on a cutture plate, and the surface was modified with polyethylene glycol to promote spheroid formation. The cells were aggregated in each microwel
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Kitano, Otome, and Kohji Nakazawa. "Neuronal Differentiation of NT2 Cells in Monolayer and Spheroid Cultures." MATEC Web of Conferences 333 (2021): 07008. http://dx.doi.org/10.1051/matecconf/202133307008.

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Metabolism and differentiation of cultured cells are influenced by changes in cellular morphology. In this study, we investigated the differences in cell proliferation and neuronal differentiation of NT2 cells in monolayer (2D) and spheroid (3D) cultures. In the monolayer culture, the cells adhered and extended on a tissue culture plate. For the spheroid culture, we fabricated a microwell chip comprising 195 circular microwells (600 ìm in diameter) on a cutture plate, and the surface was modified with polyethylene glycol to promote spheroid formation. The cells were aggregated in each microwel
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Son, Young-Bum, Dinesh Bharti, Saet-Byul Kim, et al. "Comparison of Pluripotency, Differentiation, and Mitochondrial Metabolism Capacity in Three-Dimensional Spheroid Formation of Dental Pulp-Derived Mesenchymal Stem Cells." BioMed Research International 2021 (July 13, 2021): 1–10. http://dx.doi.org/10.1155/2021/5540877.

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Mesenchymal stem cells (MSCs) are valuable candidates in tissue engineering and stem cell-based therapy. Traditionally, MSCs derived from various tissues have been successfully expanded in vitro using adherent culture plates commonly called as monolayer two-dimensional (2D) cultures. Recently, many studies demonstrated that stemness and multilineage differentiation potential could be enhanced to greater extent when MSCs are cultured as suspended aggregates by means of three-dimensional (3D) culturing techniques. However, there are limited reports on changed mitochondrial metabolism on 3D spher
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Borzenok, S. A., I. A. Popov, I. N. Saburina, and P. M. Arbukhanova. "IN VITRO INVESTIGATION OF THE TRANSPLANTATION PROSPECTS OF MULTICELLULAR SPHEROID MICROAGGREGATES OF DONOR RETINAL PIGMENT EPITHELIUM." Russian Journal of Transplantology and Artificial Organs 17, no. 3 (2015): 58–64. http://dx.doi.org/10.15825/1995-1191-2015-3-58-64.

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Aim. To study in experiment the criteria for transplantability of multicellular spheroid microaggregates of retinal pigment epithelium (RPE), prepared by the method of 3D cell culture. Materials and Methods. 11 donor eyes (6 of adrenaline index «A», 5 of index «B») were used as a source of RPE cell cultures (group «A» – 6 cultures, group «B» – 5 cultures), of which over 2000 RPE spheroids were obtained by the method of three-dimensional cell culture. 1760 spheroids of them were selected for transplantability investigation (960 – group «A», 800 – group «B»). Among the selected spheroids were eq
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Ko, J. Y., E. Lee, J. Kim, and G. I. Im. "THU0058 ENHANCEMENT OF CARTILAGE REGENERATION EFFICIENCY WITH HUMAN ADIPOSE STEM CELL THREE-DIMENSIONAL SPHEROID." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 241.2–241. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4022.

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Background:3D (three-dimensional) cell culture technology has been researched steadily because of its high potential of biocompatibility compared to single cells since 1990s, and is being developed to 3D spheroids recently. Spheroids are considered to reflect the natural organization of cells better than 2D cell cultures, and stem cells spheroids have been studied extensively in therapeutic transplantation. Stem cells were considered as a method of replacing autologous chondrocyte in regenerative treatment of articular cartilage. Compared to conventional single cells, 3D cell culture is artifi
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Lee, Mason A., Kensey N. Bergdorf, Courtney J. Phifer, et al. "Novel three-dimensional cultures provide insights into thyroid cancer behavior." Endocrine-Related Cancer 27, no. 2 (2020): 111–21. http://dx.doi.org/10.1530/erc-19-0374.

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Thyroid cancer has the fastest growing incidence of any cancer in the United States, as measured by the number of new cases per year. Despite advances in tissue culture techniques, a robust model for thyroid cancer spheroid culture is yet to be developed. Using eight established thyroid cancer cell lines, we created an efficient and cost-effective 3D culture system that can enhance our understanding of in vivo treatment response. We found that all eight cell lines readily form spheroids in culture with unique morphology, size, and cytoskeletal organization. In addition, we developed a high-thr
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Tesis sobre el tema "3D cell culture, spheroids"

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Timmins, Nicholas E. "Extending the third dimension : novel methods and applications for 3D multicellular spheroids /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18289.pdf.

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Pyne, Emily Seton. "The Impact of Stromal Cells on the Metabolism of Ovarian Cancer Cells in 3D Culture." Thesis, Virginia Tech, 2017. http://hdl.handle.net/10919/74931.

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Academic: Ovarian cancer is the leading cause of death among female gynecologic cancers. Current treatments include surgical debulking, and chemotherapy. However, better interventions are needed to reduce the mortality rate of metastatic disease. Ovarian cancer cells have displayed the ability to aggregate and form 3D homogeneous and heterogeneous spheroids, which can function as micrometastases. Ovarian cancer spheroids survive independently prior to adhering to an endothelial tissue. Since aggregation has been shown to provide a survival advantage to the spheroids and increased their aggres
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Yang, Mandy. "An investigation of the antifungal and antitumor activity of ajoene." Thesis, University of Canterbury. Biological sciences, 2013. http://hdl.handle.net/10092/8201.

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The garlic extract ajoene is considered to have antimicrobial and antitumor effects against a variety of cell types, and it is suggested to have the potential to be used as an antifungal or antitumor drug clinically. The underlying mechanism of its inhibitory effects is still uncertain. In this project, the effects of ajoene on the growth of fungal and oomycete cells were studied on Candida albicans, Neurospora crassa and Achlya bisexualis. Endometrial cancer is the most common gynecologic cancer. A 3D spheroid model of endometrial cancer cells were for the first time used to i
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Kashtl, Ghasaq J. "Differential membrane-type matrix metalloproteinase expression in phenotypically defined breast cancer cell lines: Comparison of MT-MMP expression in environmentally-challenged 2D monolayer cultures and 3D multicellular tumour spheroids." Thesis, University of Bradford, 2018. http://hdl.handle.net/10454/17346.

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Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases capable of digesting the extracellular matrix (ECM), which is essential for tissue structure and transmitting messages between cells. MMPs play an important role in cancer, controlling cell migration, proliferation, apoptosis, regulation of tumour expansion, angiogenesis and invasion. Previous research has indicated high expression of MT1-MMP in breast cancers suggesting a potential role in tumour progression. Our results confirm that 3D multicellular tumour spheroids (MCTS) using phenotype-specific breast cancer cell lines a
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Chamayou, Léo. "LiverPearls, une méthode de culture multicellulaire miniaturisée et à haut débit reproduisant l’environnement physiologique et la structure tridimensionnelle du foie humain." Thesis, Université Paris sciences et lettres, 2020. http://www.theses.fr/2020UPSLS005.

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L’intérêt pour de nouveaux modèles de foie, plus proches physiologiquement du foie in vivo, est élevé, en particulier en provenance de l’industrie pharmaceutique. En effet, les systèmes standards, tels que la culture en 2D ne sont pas très prédictifs pour certaines études et de meilleurs modèles sont nécessaires, à la fois dans le cadre des études ADME/Tox pour le développement de médicaments ou pour modéliser les nombreuses maladies hépatiques. Afin de reproduire le foie humain, un modèle doit imiter sa structure de façon plus proche que les systèmes en 2D et refléter sa composition cellulair
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Senkowski, Wojciech. "High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities." Doctoral thesis, Uppsala universitet, Cancerfarmakologi och beräkningsmedicin, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-320598.

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High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. Monolayer cultures are highly proliferative and generally do not contain quiescent cells, thought to be one of the main reasons for the anticancer therapy failure in clinic. Thus, there is a need for in vitro cellular models that would increase predictive value of
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Christakou, Athanasia. "Ultrasound-assisted Interactions of Natural Killer Cells with Cancer Cells and Solid Tumors." Doctoral thesis, KTH, Biomedicinsk fysik och röntgenfysik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-158522.

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In this Thesis, we have developed a microtechnology-based method for culturing and visualizing high numbers of individual cells and cell-cell interactions over extended periods of time. The foundation of the device is a silicon-glass multiwell microplate (also referred as microchip) directly compatible with fluorescence microscopy. The initial microchip design involved thousands of square wells of sizes up to 80 µm, for screening large numbers of cell-cell interactions at the single cell level. Biocompatibility and confinement tests proved the feasibility of the idea, and further investigation
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Ohlin, Mathias. "Ultrasonic Fluid and Cell Manipulation." Doctoral thesis, KTH, Biomedicinsk fysik och röntgenfysik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-166779.

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During the last decade, ultrasonic manipulation has matured into an important tool with a wide range of applications, from fundamental cell biological research to clinical and industrial implementations. The contactless nature of ultrasound makes it possible to manipulate living cells in a gentle way, e.g., for positioning, sorting, and aggregation. However, when manipulating cells using ultrasound, especially using high acoustic amplitudes, a great deal of heat can be generated. This constitutes a challenge, since the viability of cells is dependent on a stable physiological temperature aroun
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Dubois, Clémence. "Optimisation du traitement du cancer du sein Triple-Négatif : développement des modèles de culture cellulaire en trois dimensions, efficacité de l'Olaparib (anti-PARP1) en combinaison avec la radiothérapie et chimiorésistance instaurée par les protéines Multi Drug Résistance." Thesis, Université Clermont Auvergne‎ (2017-2020), 2018. http://www.theses.fr/2018CLFAS018/document.

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Le cancer du sein est une maladie complexe et difficile à caractériser. Parmi les différents sous-types moléculaires, les tumeurs du sein Triple-Négatives (TN) sont particulièrement agressives et de mauvais pronostic. Elles sont caractérisées par une absence d’expression des récepteurs aux œstrogènes (ER), à la progestérone (PR), l’absence de surexpression du récepteur Human Epidermal growth factor 2 (HER2) et de fréquentes mutations sur les gènes BRCA1/2 (profil « BRCAness »). En absence de thérapies ciblées efficaces, de nombreux traitements ciblés notamment les inhibiteurs de poly-ADP-ribos
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Pasqua, Mattia. "Preclinical studies on an extracorporeal bioartificial liver." Thesis, Compiègne, 2020. http://www.theses.fr/2020COMP2557.

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Pour tous les patients souffrant d'une insuffisance hépatique aigue, il existe un besoin urgent de solutions alternatives à la transplantation du foie. En raison de divers facteurs, ces patients n'ont pas toujours accès à un organe et meurent dans l’attente d’une greffe. Il est donc impératif de trouver des alternatives viables à la transplantation du foie. Parmi les différentes alternatives apparues ces dernières années, notre groupe a principalement étudié le concept de foie bioartificiel. Il s'agit d'un dispositif de circulation extracorporelle équipé d'éléments artificiels (charbon actif e
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Libros sobre el tema "3D cell culture, spheroids"

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Haycock, John W., ed. 3D Cell Culture. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60761-984-0.

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Koledova, Zuzana, ed. 3D Cell Culture. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7021-6.

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3D cell culture: Methods and protocols. Humana Press/Springer, 2011.

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Haycock, John W. 3D cell culture: Methods and protocols. Humana Press/Springer, 2011.

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Przyborski, Stefan, ed. Technology Platforms for 3D Cell Culture. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781118851647.

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Kasper, Cornelia, Dominik Egger, and Antonina Lavrentieva, eds. Basic Concepts on 3D Cell Culture. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66749-8.

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Dutta, Ranjna C., and Aroop K. Dutta. 3D Cell Culture. Jenny Stanford Publishing, 2018. http://dx.doi.org/10.1201/b22417.

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3D Stem Cell Culture. MDPI, 2021. http://dx.doi.org/10.3390/books978-3-03943-804-4.

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Kisaalita, William S. 3D Cell Culture: Principles and Applications. Taylor & Francis Group, 2022.

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Przyborski, Stefan. Technology Platforms for 3D Cell Culture: A User's Guide. Wiley & Sons, Incorporated, John, 2017.

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Capítulos de libros sobre el tema "3D cell culture, spheroids"

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Slawny, Nicole A., and MaryAnn Labant. "Physiologically relevant spheroid models for three-dimensional cell culture." In Technology Platforms for 3D Cell Culture. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781118851647.ch3.

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Wrzesinski, Krzysztof, Helle Sedighi Frandsen, Carlemi Calitz, Chrisna Gouws, Barbara Korzeniowska, and Stephen J. Fey. "Clinostat 3D Cell Culture: Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1246-0_2.

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Evans, David M., and Beverly A. Teicher. "3D Cell Culture Models." In Molecular and Translational Medicine. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-57424-0_19.

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Duarte Campos, Daniela F., and Andreas Blaeser. "3D-Bioprinting." In Basic Concepts on 3D Cell Culture. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66749-8_9.

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Koledova, Zuzana. "3D Cell Culture: An Introduction." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7021-6_1.

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Lavrentieva, Antonina, and Jane Spencer-Fry. "Hydrogels for 3D Cell Culture." In Basic Concepts on 3D Cell Culture. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66749-8_5.

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Egger, Dominik, and Sabrina Nebel. "Introduction to 3D Cell Culture." In Basic Concepts on 3D Cell Culture. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66749-8_1.

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Markou, M., D. Kouroupis, T. Fotsis, E. Bagli, and C. Murphy. "Vascularization in 3D Cell Culture." In Basic Concepts on 3D Cell Culture. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66749-8_6.

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Navran, Stephen S. "Three-dimensional cell culture in the Rotary Cell Culture System™." In Technology Platforms for 3D Cell Culture. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781118851647.ch16.

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Campbell, Madeline, Mamta Chabria, Gemma A. Figtree, Liudmila Polonchuk, and Carmine Gentile. "Stem Cell-Derived Cardiac Spheroids as 3D In Vitro Models of the Human Heart Microenvironment." In Stem Cell Niche. Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_187.

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Actas de conferencias sobre el tema "3D cell culture, spheroids"

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Lim, Sei Hien, Chee Mun Kuan, Marco Campisi, Valeria Chiono, and Andrea Pavesi. "Abstract 47: Analyzing immune cell infiltration of cancer spheroids in a 3D cell culture platform." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-47.

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Lim, Sei Hien, Chee Mun Kuan, Marco Campisi, Valeria Chiono, and Andrea Pavesi. "Abstract 47: Analyzing immune cell infiltration of cancer spheroids in a 3D cell culture platform." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-47.

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Marshall, Lauren, Andra Frost, Tim Fee, and Joel Berry. "Assembly and Characterization of 3D, Vascularized Breast Cancer Tissue Mimics." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14199.

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Drug development platforms such as two-dimensional (2D) in vitro cell culture systems and in vivo animal studies do not accurately predict human in vivo effectiveness of candidate therapeutics [1]. Cell culture systems have limited similarities to primary human cells and tissues as only one cell type is employed and animal studies have a generally limited ability to recapitulate human drug response as different species have differences in metabolism, physiology, and behavior. Mike Leavitt, a former U.S. Secretary of Health and Human Services, has stated that “currently, nine out of ten experim
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Kim, T., and Y. H. Cho. "On-chip formation and perfusion culture of 3D tumor spheroids using gravity-driven cell aggregation and pumpless balanced droplet dispensing." In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2012. http://dx.doi.org/10.1109/memsys.2012.6170324.

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Jakob, Y., S. Reutter, D. Gvaramia, N. Rotter, and J. Kern. "Investigation of effects of 3D spheroid culture and different cell culture media on the proliferation of chondrocytes in-vitro." In 100 JAHRE DGHNO-KHC: WO KOMMEN WIR HER? WO STEHEN WIR? WO GEHEN WIR HIN? Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1728952.

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Norberg, Jessica K., Salvatore Nania, Rainer L. Heuchel, and Matthias J. Löhr. "Abstract C40: Pancreatic cancer and stroma cell cross-talk affects cell proliferation in a 3D spheroid co-culture model." In Abstracts: AACR Special Conference: The Function of Tumor Microenvironment in Cancer Progression; January 7-10, 2016; San Diego, CA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.tme16-c40.

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Asbrock, Nick, Vi Chu, and Kan Saito. "Abstract 927: Cancer stem cell proliferation in human prostate cancer cells utilizing a new defined 3D spheroid culture system." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-927.

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YU Skorova, Ekaterina, Evgenia Shabalina, Daria Chudakova, et al. "Differential Response to the High Doses of Dimethyl Sulfoxide of the Several Human Cancer Cell Lines Cultured in 2D Monolayer, Decellularized Matrix, and 3D Spheroid cell Culture Systems." In ICBBE '20: 2020 7th International Conference on Biomedical and Bioinformatics Engineering. ACM, 2020. http://dx.doi.org/10.1145/3444884.3444916.

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Nishimura, Keigo, Minghao Nie, and Shoji Takeuchi. "3D Microfluidic Device for Perfusion Culture of Spheroids." In 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2020. http://dx.doi.org/10.1109/mems46641.2020.9056442.

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Weltin, A., S. Hammer, Y. Kaminski, et al. "Continuous lactate monitoring by microsensors in spheroid 3D tumor cell cultures." In TRANSDUCERS 2015 - 2015 18th International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2015. http://dx.doi.org/10.1109/transducers.2015.7181270.

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Informes sobre el tema "3D cell culture, spheroids"

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Malik, Abir, D. Lam, H. A. Enright, S. K. G. Peters, B. Petkus, and N. O. Fischer. Characterizing the Phenotypes of Brain Cells in a 3D Hydrogel Cell Culture Model. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1466140.

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Mastro, Andrea M. Altering the Microenvironment to Promote Dormancy of Metastatic Breast Cancer Cell in a 3D Bone Culture System. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada604844.

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Mastro, Andrea M., and Erwin Vogler. Altering the Microenvironment to Promote Dormancy of Metastatic Breast Cancer Cell in a 3D Bone Culture System. Defense Technical Information Center, 2015. http://dx.doi.org/10.21236/ada621382.

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