Literatura académica sobre el tema "974"
Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros
Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "974".
Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.
También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.
Artículos de revistas sobre el tema "974"
Pastuszko, Marian. "Uprawnienie do sprawowania sakramentu pokuty i pojednania (kanony 966-975 i kan. 144 §§1-2)". Prawo Kanoniczne 37, n.º 3-4 (20 de diciembre de 1994): 191–245. http://dx.doi.org/10.21697/pk.1994.37.3-4.14.
Texto completoMassicotte-Azarniouch, David, Sheldon Magder, Peter Goldberg y Ahsan Alam. "974". Critical Care Medicine 43 (diciembre de 2015): 245. http://dx.doi.org/10.1097/01.ccm.0000474802.32861.df.
Texto completoBardhan, Bonny, Gianfranco Meduri, Cynthia Rovnaghi y Kanwaljeet Anand. "974". Critical Care Medicine 40 (diciembre de 2012): 1–328. http://dx.doi.org/10.1097/01.ccm.0000425187.08057.0b.
Texto completoMatsui, Satoshi, Toru Hifumi, Nobuaki Kiriu, Eiju Hasegawa, Tomoko Ogasawara, Hiroshi Kato y Yuichi Koido. "974". Critical Care Medicine 41 (diciembre de 2013): A245. http://dx.doi.org/10.1097/01.ccm.0000440212.50201.19.
Texto completoMargoles, Lindsay, Rohit Mittal, Mara Serbanescu, Zhe Liang, John Lyons, Mandy Ford y Craig Coopersmith. "974". Critical Care Medicine 42 (diciembre de 2014): A1594—A1595. http://dx.doi.org/10.1097/01.ccm.0000458471.71413.d4.
Texto completoPence, L., A. Cano, L. Ward y B. Thorn. "(974)". Journal of Pain 7, n.º 4 (abril de 2006): S92. http://dx.doi.org/10.1016/j.jpain.2006.01.376.
Texto completoKeshary, Meera, Arushi Manga y Nikoleta Kolovos. "974". Critical Care Medicine 47 (enero de 2019): 465. http://dx.doi.org/10.1097/01.ccm.0000551722.23547.65.
Texto completoHahn, Matthew. "Applied Theatre and Sexual Health Communication: Apertures of Possibility, Katharine E. Low (2020)". Journal of Applied Arts & Health 13, n.º 2 (1 de julio de 2022): 267–69. http://dx.doi.org/10.1386/jaah_00106_5.
Texto completoKatherine Ward, H., J. Brierley y B. Saikia. "ABSTRACT 974". Pediatric Critical Care Medicine 15 (mayo de 2014): 215. http://dx.doi.org/10.1097/01.pcc.0000449700.44688.54.
Texto completoNovoselsky, Alexander y Eugene Kagan. "Algorithm 974". ACM Transactions on Mathematical Software 43, n.º 4 (23 de marzo de 2017): 1–3. http://dx.doi.org/10.1145/3054078.
Texto completoTesis sobre el tema "974"
Stanley, Alison. "Language and identity in the literature of the seventeenth-century New England Puritans". Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/language-and-identity-in-the-literature-of-the-seventeenthcentury-new-england-puritans(e8dcb8d8-a634-494f-80e3-d8dbd6078c69).html.
Texto completoMeenagh, Martin Lee. "John J. Hughes, first Archbishop of New York, and the Atlantic Irish, c. 1841-c. 1864". Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275762.
Texto completoWiesner, Susan L. "Framing dance writing : a corpus linguistics approach". Thesis, University of Surrey, 2007. http://epubs.surrey.ac.uk/974/.
Texto completoAl-Tasan, Hamad Saleh A. "An evaluation of housing finance in Saudi Arabia : the Real Estate Development Fund's policies and alternative options". Thesis, Durham University, 1998. http://etheses.dur.ac.uk/974/.
Texto completoBocchialini, Elisa <1980>. "Le scelte di investimento dei fondi pensioni italiani: un’analisi degli asset immobiliari". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/974/.
Texto completoAlmagro, García Ma Cristina de. "Paper de la UGT1A6 en la resistència al metotrexat : estudi dels harpins de polipurines per disminuir l'expressió gènica". Doctoral thesis, Universitat de Barcelona, 2010. http://hdl.handle.net/10803/974.
Texto completoEn el present estudi, hem analitzat la resistència al MTX en cèl·lules de càncer de mama. S'han realitzat microarrays d'expressió amb dues línies cel·lulars sensibles i resistents al MTX, els quals han originat com a únic gen en comú entre les cèl·lules resistents d'ambdues línies la família de les UDP-glucuronosil transferases (UGT1A). Hem estudiat aquesta família de gens, i s'ha identificat la UGT1A6 com la principal responsable de la sobrexpressió de les UGTs a les cèl·lules resistents. En aquest treball s'ha analitzat la implicació de la UGT1A6 en la resistència al MTX. També hem analitzat la inducció transcripcional del MTX sobre la UGT1A6, així com els factors transcripcionals involucrats en aquest procés. A més, s'han estudiat les repercussions terapèutiques que pot tenir la sobrexpressió de la UGT1A6 quan es dóna MTX en combinació amb altres fàrmacs glucuronidables.
Dins de la recerca de nous mètodes per inhibir la DHFR diferents als quimioteràpics clàssics com el MTX, trobem els basats en teràpia gènica. En treballs anteriors del nostre grup s'havien desenvolupat diversos tipus de molècules per disminuir l'expressió de la dhfr, tal com oligonucleòtids antisentit (aODNs), siRNAs i Triplex forming oligonucleotides (TFOs).
En aquest treball hem desenvolupat Template-PPRHs i Coding-PPRHs, hairpins destinats a unir-se a la cadena motlle o codificant del DNA i mRNA, respectivament. Hem estudiat la capacitat citotòxica que tenen els PPRHs en cèl·lules de càncer de mama utilitzant com a model el gen dhfr humà, així com el mecanisme d'acció pel qual aquestes molècules inhibeixen la DHFR. També hem analitzat la capacitat in vitro dels hairpins d'unir-se a la seva seqüència diana i la influència que té la presència d'interrupcions de purines en la cadena de polipirimidines i la forma de minimitzar els seus efectes. Així mateix, hem estudiat l'estabilitat d'aquestes molècules, la seva especificitat i l'activació de la resposta immune. S'ha analitzat l'aplicació terapèutica a partir de l'utilització de PPRHs contra la dhfr en cèl·lules de càncer de mama resistents al MTX, així com el disseny de diferents PPRHs dirigits contra gens amb importància terapèutica en càncer.
The main objective of this work is the study of the mechanisms that lead to resistance to the chemotherapeutic methotrexate (MTX) in cancerous cells. To study this phenomenon there have been two approaches: the search of new strategies to inhibit the expression of the dihydrofolate reductase (DHFR), the main responsible for MTX resistance; and the study of new genes that could be involved in MTX resistance.
A microarrays analysis between two breast cancer cell lines sensitive and methotrexate resistant pointed out the UDP-glucuronosyltransferase 1A (UGT1A) family as a common deregulated node in both cell lines. UGT1A6 was the main isoform responsible for UGT1A family overexpression in these cells and this overexpression was not due to gene amplification. The importance of UGT1A6 overexppression in MTX resistance was studied as well as the induction of UGT1A6 mRNA levels and enzymatic activity carried out by MTX through the transcription factors ARNT (HIF-1) and AhR/ARNT. Cells incubated with anticancer drugs susceptible to glucuronidation together with MTX, showed a lesser degree of cytotoxicity, due to UGT1A6 induction. The pharmacological effect of this induction should be taken into account when combining MTX with other drugs that are glucuronidated.
Polypurine Reverse-Hoogsteen hairpins, PPRHs, are dsDNA molecules formed by two polypurine stretches linked by a pentathymidine loop. These two polypurine domains are bound by intramolecular Reverse-Hoogsteen bonds, allowing the formation of a hairpin structure. PPRHs bind to their targets by Watson-Crick, forming triplex structures. We designed two types of PPRHS: Template-PPRHs and Coding-PPRHs. Template-PPRHs are designed to bind the template DNA strand, whereas Coding-PPRHs target the mRNA and the coding DNA strand. The dhfr gene was selected as a target in breast cancer therapy. Both PPRHs caused a high degree of cytotoxicity and a decrease in DHFR mRNA and protein levels, but through different mechanisms of action. Template-PPRHs decrease mRNA levels since they interfere with the transcription process. Coding-PPRHs interfere with the splicing process by competing with U2AF65 for binding to the polypyrimidine target sequence, leading to a lower amount of mature mRNA. PPRHs can be considered as new molecules to decrease gene expression.
Zajc, Elizabeth. "Modelling native bird diversity in the Greater Toronto Area". Thesis, University of Waterloo, 2005. http://hdl.handle.net/10012/974.
Texto completoA database of breeding bird data and landscape information, in a geographic information system platform, was used to investigate the comparative strength of the competing hypotheses for the Greater Toronto Area. A mathematical expression with a Poisson model format was created to represent each hypothesis. The model selection technique based on Kullback-Leibler information using the Akaike Information Criterion was deemed most appropriate for the comparison of the models. Four separate Poisson model competitions were completed using two habitat types and two response variables: species richness and total abundance. In three of the four competitions, the best model included the habitat area and the amount of urbanization in the landscape. In the forth competition, this model was considered as strong as another model which included habitat area, amount of habitat in the landscape and degree of fragmentation. The results from the model competition support the hypothesis that habitat area is important, but landscape variables must also be considered to explain avian richness and total abundance. It appears that maintaining native bird biodiversity in the Greater Toronto Area should focus on preserving and possibly increasing habitat area and decreasing adjacent urbanization. Exploration of the best model in the forest analysis with the richness response variable found that a 10% increase in habitat area cause approximately a 10% increase in species richness, and a 10% increase in urban area caused approximately a 20% decrease in species richness. Consequently, current natural heritage planning in Ontario should consider urban development as an important negative effect on native birds.
McCracken, Robert. "Face Saving at the Singles Bar: Effects of Women's Perspectives of Men and Their Performances on Women's Methods of Rejection". TopSCHOLAR®, 1994. http://digitalcommons.wku.edu/theses/974.
Texto completoHallam, Edward James. "An evaluation of product quality and consumer satisfaction in the FMCG market : Pick 'n Pay hypermarket, Port Elizabeth". Thesis, Nelson Mandela Metropolitan University, 2008. http://hdl.handle.net/10948/974.
Texto completoJiang, Haiyan. "Three essays on ownership concentration in New Zealand". Diss., Lincoln University, 2009. http://hdl.handle.net/10182/974.
Texto completoLibros sobre el tema "974"
Christian, Vittori, ed. Graffiti 974. Sainte-Marie (Réunion)]: Azalées Éditions, 2011.
Buscar texto completoRéunion (Region). Service interministériel régional de défense et de protection civile., ed. Sécurité civile 974. Saint Denis Cédex: Préfecture de la Réunion, Service interministériel régional de défense et de protection civile, 1994.
Buscar texto completoUnited States. Internal Revenue Service, ed. Notice 974, (Revised November 1997). [S.l: s.n., 1998.
Buscar texto completoNicaragua. Ley de seguridad social: Decreto 974 : anexos ... 6a ed. [Managua]: Editorial Jurídica, 2008.
Buscar texto completoNicaragua. Ley de seguridad social: Decreto 974 : anexos ... 6a ed. [Managua]: Editorial Jurídica, 2008.
Buscar texto completoUnited States. Congress. Senate. Committee on Energy and Natural Resources. Nevada Wilderness Protection Act of 1989: Report (to accompany S. 974). [Washington, D.C.?: U.S. G.P.O., 1989.
Buscar texto completo1960-, Murphy Gregory, Hydrick Blair, University Publications of America (Firm) y United States. Dept. of State., eds. Confidential U.S. State Department central files.: Decimal numbers 774, 874, and 974. Frederick, MD: University Publications of America, 1989.
Buscar texto completoRules, United States Congress House Committee on. Providing for the consideration of S. 974: Report (to accompany H. Res. 289). [Washington, D.C.?: U.S. G.P.O., 1989.
Buscar texto completoUnited States. Congress. House. Committee on Rules. Providing for the consideration of S. 974: Report (to accompany H. Res. 289). [Washington, D.C.?: U.S. G.P.O., 1989.
Buscar texto completoCapítulos de libros sobre el tema "974"
Jain, M. y A. Gupta. "974 Diamagnetic susceptibility of C4H6O4Pb". En Diamagnetic Susceptibility and Anisotropy of Inorganic and Organometallic Compounds, 1024. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-44694-1_975.
Texto completoKumar, M. "974 Chemical Shifts and Coupling Constants for C9H11N2O3PS". En Chemical Shifts and Coupling Constants for Phosphorus-31, 983. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-32069-9_976.
Texto completoWang, Cheng Yong, Ying Ning Hu, Z. W. Wang y H. N. Ding. "Noise and Vibration of Diamond Sawblade for Concrete Dry Cutting". En Advances in Abrasive Technology VIII, 103–8. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.103.
Texto completoWu, Yan, Bo Zhao y Xun Sheng Zhu. "Force Characteristics in Ultrasonic Vibration Grinding of Nanoceramics". En Advances in Abrasive Technology VIII, 109–14. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.109.
Texto completoZhang, Fei Hu, J. C. Gui, Yi Zhi Liu y Hua Li Zhang. "Experimental Research on ELID Grinding and Cutting Performance of Nano Cemented Carbide Cutters". En Advances in Abrasive Technology VIII, 115–20. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.115.
Texto completoDai, Y., Hitoshi Ohmori, Wei Min Lin, H. Eto, N. Ebizuka y K. Tsuno. "ELID Grinding Properties of High-Strength Reaction-Sintered SiC". En Advances in Abrasive Technology VIII, 121–26. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.121.
Texto completoShen, Jian Yun, Wei Min Lin, Hitoshi Ohmori y Xi Peng Xu. "Characterization of ELID-Ground Granite Surfaces". En Advances in Abrasive Technology VIII, 127–32. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.127.
Texto completoZhang, Fei Hu, L. J. Li y Shen Dong. "Surface Quality Improvement of Aspheric Pressing Mould Using Parallel Grinding Method". En Advances in Abrasive Technology VIII, 133–38. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.133.
Texto completoKang, X., Junichi Tamaki, Akihiko Kubo, Ji Wang Yan y Toshirou Iyama. "Effect of Cutting Edge Truncation on Ground Surface Morphology of Hard and Brittle Materials for Optical Devices". En Advances in Abrasive Technology VIII, 139–44. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.139.
Texto completoCao, L. X., H. J. Wu y J. Liu. "Kinematic Analysis of Face Grinding Process at Lapping Machines". En Advances in Abrasive Technology VIII, 145–50. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-974-1.145.
Texto completoActas de conferencias sobre el tema "974"
"Back Matter for Volume 974". En COMPUTATION IN MODERN SCIENCE AND ENGINEERING: Proceedings of the International Conference on Computational Methods in Science and Engineering 2007 (ICCMSE 2007): VOLUME 2, PARTS A and B. American Institute of Physics, 2008. http://dx.doi.org/10.1063/v974.backmatter.
Texto completo"Front Matter for Volume 974". En COMPUTATION IN MODERN SCIENCE AND ENGINEERING: Proceedings of the International Conference on Computational Methods in Science and Engineering 2007 (ICCMSE 2007): VOLUME 2, PARTS A and B. American Institute of Physics, 2008. http://dx.doi.org/10.1063/v974.frontmatter.
Texto completoSahraoui, G., B. Malek, R. Sellami, L. Charfi, I. Abess, N. Boujelbene, K. Mrad y R. Doghri. "974 Hormonal receptors expression in uterine leiomyosarcomas". En ESGO 2021 Congress. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/ijgc-2021-esgo.217.
Texto completoRoman, Theodore, Brenda Xiao y Russell Schwartz. "Abstract 974: Automating deconvolution of heterogeneous bulk tumor genomic data". En Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-974.
Texto completoSolé-Sedeño, Josep Maria, Júlia Castellà Cesari, Ester Miralpeix Rovira, Álvaro Taus Garcia y Gemma Mancebo Moreno. "#974 Does biochemical monitoring have any role in ovarian cancer?" En ESGO 2023 Congress. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/ijgc-2023-esgo.677.
Texto completoHanna, D. C., H. M. Pask, J. E. Townsend, J. L. Archambault, L. Reekie y A. C. Tropper. "Yb-Doped Silica Cladding-Pumped Fiber Laser Pumped at 974 nm". En Advanced Solid State Lasers. Washington, D.C.: OSA, 2004. http://dx.doi.org/10.1364/assl.1994.yl1.
Texto completoAppleman, Victoria A., Michael D. Smith, Michelle Ganno, Tiquella Hatten, Maria Borland y Adnan O. Abu-Yousif. "Abstract 974: Immune modulation following combination of TAK-164 with checkpoint inhibitors". En Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-974.
Texto completoEtten, Jamie L. Van, Michael Nyquist, Yingming Li, Rebecca LaRue, Yeung Ho, Rendong Yang, Daniel F. Voytas, Christine Henzler y Scott M. Dehm. "Abstract 974: Alternative polyadenylation of androgen receptor variants in castration-resistant prostate cancer". En Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-974.
Texto completoMa, Wenxue, Alejandro Gutierrez, Daniel Goff, Ifat Geron, Anil Sadarangani, Alice Shih, Angela Court Recart et al. "Abstract 974: A selective Notch1 mAb targets leukemia progenitor cells in T-ALL". En Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-974.
Texto completoDemas, Jeffrey, Gautam Prabhakar, Tao He, Poul Kristensen y Siddharth Ramachandran. "High peak power 974 nm fiber source employing parametric wavelength conversion with HOM fibers". En Advanced Solid State Lasers. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/assl.2016.atu6a.2.
Texto completoInformes sobre el tema "974"
McCallen, D. B. y S. Miller. Computation of the Seismic Stability of Earth Retaining Structures Final Report CRADA No. TSB-954-94. Office of Scientific and Technical Information (OSTI), febrero de 2018. http://dx.doi.org/10.2172/1426083.
Texto completoRepond, J. T-970: DHCAL Detector Test. Office of Scientific and Technical Information (OSTI), mayo de 2007. http://dx.doi.org/10.2172/1985129.
Texto completoWei-Heng Shih. CONVERSION OF COAL WASTES INTO WASTE-CLEANING MATERIALS. FIANL REPORT (8/1/94-12/31/97). Office of Scientific and Technical Information (OSTI), enero de 1998. http://dx.doi.org/10.2172/769340.
Texto completoVaucher, Gail T., Edward Creegan y Jimmy Yarbrough. 924-MHz Wind Profiling Radar Acceptance Tests. Fort Belvoir, VA: Defense Technical Information Center, noviembre de 1998. http://dx.doi.org/10.21236/ada357711.
Texto completoSnyder, D. E. Process hazards review of the 904-A trench. Office of Scientific and Technical Information (OSTI), agosto de 1988. http://dx.doi.org/10.2172/10135048.
Texto completoWood, C. L. y M. D. Starr. Simulation Technology Laboratory Building 970 hazards assessment document. Office of Scientific and Technical Information (OSTI), noviembre de 1994. http://dx.doi.org/10.2172/28284.
Texto completoMeot, F., L. Ahrens, J. Glenn, H. Huang, A. Luccio, W. W. MacKay, T. Roser y N. Tsoupas. Zgoubi-ing AGS : spin motion with snakes and jump-quads,Gγ = 43.5 through Gγ = 46.5 and beyond. Office of Scientific and Technical Information (OSTI), octubre de 2009. http://dx.doi.org/10.2172/1043983.
Texto completoJudd, D., J. Rintamaki y S. Lund. Heavy ion fusion notes 94-1 through 94-9. Office of Scientific and Technical Information (OSTI), marzo de 1995. http://dx.doi.org/10.2172/130664.
Texto completoTremaine, Aaron. XL4 Klystron (Top level drawing AD-700-924-00). Office of Scientific and Technical Information (OSTI), diciembre de 2014. http://dx.doi.org/10.2172/1165899.
Texto completoHill, Scott, Leonard Lombardo, Jr Fling y Rick. Standardized UXO Technology Demonstration Site, Scoring Record No. 944. Fort Belvoir, VA: Defense Technical Information Center, agosto de 2014. http://dx.doi.org/10.21236/ada615911.
Texto completo