Bibliografías temáticas / Anti-adhesion

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Literatura académica sobre el tema "Anti-adhesion"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 22 de junio de 2024

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Artículos de revistas sobre el tema "Anti-adhesion"

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Anonymous. "Anti-Adhesion Gel". Orthopedics 21, n.º 4 (abril de 1998): 452. http://dx.doi.org/10.3928/0147-7447-19980401-13.

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Dedrick, Russell L., Patricia Walicke y Marvin Garovoy. "Anti-adhesion antibodies". Transplant Immunology 9, n.º 2-4 (mayo de 2002): 181–86. http://dx.doi.org/10.1016/s0966-3274(02)00029-1.

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SIMMONS, D. "Anti-adhesion therapies". Current Opinion in Pharmacology 5, n.º 4 (agosto de 2005): 398–404. http://dx.doi.org/10.1016/j.coph.2005.02.009.

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Jothy, Serge, Sandra B. Munro, Lam LeDuy, Diane McClure y Orest W. Blaschuk. "Adhesion or anti-adhesion in cancer: what matters more?" Cancer and Metastasis Reviews 14, n.º 4 (diciembre de 1995): 363–76. http://dx.doi.org/10.1007/bf00690604.

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Clark, Wayne M. y Justin A. Zivin. "Anti-Adhesion Molecule Monoclonal Antibodies". CNS Drugs 6, n.º 2 (agosto de 1996): 90–99. http://dx.doi.org/10.2165/00023210-199606020-00002.

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Wiseman, David M. "Registries for anti-adhesion products?" Fertility and Sterility 85, n.º 4 (abril de 2006): e7. http://dx.doi.org/10.1016/j.fertnstert.2006.01.005.

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Etzioni, Amos. "Anti adhesion molecules - Therapeutic applications". Pharmacological Research 31 (enero de 1995): 130. http://dx.doi.org/10.1016/1043-6618(95)86778-3.

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Wiseman, David M. "Registries for anti-adhesion products?" Fertility and Sterility 86, n.º 3 (septiembre de 2006): 771. http://dx.doi.org/10.1016/j.fertnstert.2006.07.1462.

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Sahin, Mustafa, Murat Cakir, Fatih Mehmet Avsar, Ahmet Tekin, Tevfik Kucukkartallar y Mehmet Akoz. "The Effects of Anti-Adhesion Materials in Preventing Postoperative Adhesion in Abdominal Cavity (Anti-Adhesion Materials for Postoperative Adhesions)". Inflammation 30, n.º 6 (10 de agosto de 2007): 244–49. http://dx.doi.org/10.1007/s10753-007-9043-1.

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Sheu, Shew-Meei, Bor-Shyang Sheu, Hsiao-Bai Yang, Huan-Yao Lei y Jiunn-Jong Wu. "Anti-Lewis X Antibody Promotes Helicobacter pylori Adhesion to Gastric Epithelial Cells". Infection and Immunity 75, n.º 6 (19 de marzo de 2007): 2661–67. http://dx.doi.org/10.1128/iai.01689-06.

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ABSTRACT Lewis X (Lex) antigen is expressed on the human gastric mucosa and the O-specific chain of lipopolysaccharides of Helicobacter pylori. This antigen can induce autoantibodies, which may be involved in bacterial colonization and thus deserve further investigation. Flow cytometry was used to examine the effects of anti-Le monoclonal antibodies (MAbs) on H. pylori adhesion. A babA2 mutant was also constructed to evaluate the effect of an anti-Lex MAb on adhesion. The bacterial agglutination and in situ adhesion assays were used to confirm the anti-Lex MAb effect on H. pylori adhesion. This study revealed that an anti-Lex MAb, but not an anti-Leb MAb or an anti-Ley MAb, could enhance the adhesion of H. pylori strains that expressed high levels of Lex antigen to AGS cells. The enhancement was not found on an H. pylori strain with a low level of Lex antigen. Anti-Lex MAb could increase the adhesion of both the wild-type strain and its isogenic babA2 mutant to AGS cells. When AGS cells were pretreated with anti-Lex MAb, the adhesion of the babA2 mutant also increased. Only anti-Lex MAb could promote bacterial agglutination, and the in situ adhesion assay further confirmed that adding anti-Lex MAb resulted in denser bacterial adhesion on the gastric epithelia collected from clinical patients. These results suggest anti-Lex MAb could specifically enhance the adhesion abilities of H. pylori strains through a mechanism by which anti-Lex MAb promotes bacterial aggregation and mediates bivalent interaction (antigen-antibody-antigen) between bacteria and host cells.
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Tesis sobre el tema "Anti-adhesion"

1

Dagia, Nilesh M. "Transcription Inhibitors as Anti-Adhesion Agents". Ohio University / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1089820343.

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Heinemann, Gijzen Christine. "Lactobacilli biosurfactants as anti-adhesion molecules against uropathogens". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0006/MQ42154.pdf.

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Mustaffa, Khairul. "Investigations of anti-adhesion and endothelial environment for Plasmodium falciparum cytoadherence". Thesis, University of Liverpool, 2011. http://livrepository.liverpool.ac.uk/5773/.

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A unique feature of mature Plasmodium falciparum (P. falciparum) parasitized RBC (pRBC) is that they bind to surface molecules of microvasculature endothelium via the parasite-derived surface protein PfEMP1. This ligand is associated with the cytoadherence pathology seen in severe malaria (SM) and recently our group has shown that even when treated with effective anti-malarial drug, pRBC are still able to cytoadhere, therefore, there is a need to find an adjunct treatment (in addition to antimalarial drugs) that can inhibit and reverse the adhesion process. Previous reports have suggested that sulphated glycoconjugates are highly effective at disrupting P. falciparum pRBC rosettes. Here, we investigate that effect by using sulphated polysaccharides and modified heparin for their effect to interrupt pRBC sequestration. We found that not all sulphated compounds or modified heparins were able to interrupt the sequestration process. Consideration of the inhibitory compounds generated some 18rules 19 fore exhibition of inhibitory properties: Sulphate position either at 6-O, or/and 2-O sulphate and N-sulphate is necessary for each compound. In addition, the multivalent effect and drug exhibit low anticoagulant activity also determined an active response to inhibit and de-sequestered P. falciparum pRBC on protein and endothelial cells. Here, we provide evidence that polysaccharides that possess a different level of sulphate, conformational structure and sulphate position act differently. This study also addressed the importance of pH host environment and extracellular matrix (glycocalyx) on the surface of endothelial cells on mediating pRBC binding. It found that pRBC bind significantly higher at pH 7-7.2 to CD36 and ICAM-1. Meanwhile, glycocalyx might interact as an instantaneous binder before pRBC reached ICAM-1 or CD36, unfortunately we cannot prove this due to methods and antibody chosen. The work reported in this thesis opens up new possibilities for therapeutic strategies targeting binding interaction of pRBC to host cells.
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4

Hage, Mayssane. "Understanding the mechanisms of interactions at interfaces between bacteria and materials : development of anti-adhesion and anti-biofilm surfaces". Electronic Thesis or Diss., Université de Lille (2018-2021), 2021. http://www.theses.fr/2021LILUR037.

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L’environnement opératoire dans les domaines alimentaire et médical permet aux bactéries de se fixer et de se développer sur les surfaces, ce qui entraîne la formation de biofilms bactériens pathogènes et résistants. Ces structures pathogènes sont responsables de plusieurs maladies d'origine alimentaire et d'infections nosocomiales. Par conséquent, pour lutter contre ce fléau de santé publique, une approche possible est l'utilisation des technologies plasma froid pour l’élaboration de revêtements sur différents matériaux. Ce travail présente les différents facteurs influençant l'adhésion bactérienne à un substrat. En outre, les stratégies d’élaboration de revêtements passifs visant à prévenir la formation de biofilms par des traitements de surface par plasma froid sont décrites ainsi que les propriétés antiadhésives des surfaces élaborées. Les aspects généraux du revêtement, y compris les modifications physicochimiques de la surface et l'utilisation des technologies par plasma froid, sont également présentés. Dans ce contexte, une étude a été menée dans le but d'inhiber l'adhésion de la bactérie pathogène Salmonella enterica à la surface de l'acier inoxydable, via son traitement par plasma froid. Dans le but de limiter la formation du biofilm de Salmonella enterica, des revêtements organosiliciés à partir du monomère 1,1,3,3-tétraméthyldisiloxane, mélangé ou non à l’oxygène, ont été élaborés par polymérisation par plasma post-décharge micro-ondes d'azote. L'effet des paramètres du plasma froid sur les propriétés du revêtement, sur la topographie de la surface et sur l'adhésion des cellules Salmonella enterica a été étudié. Les résultats ont révélé que la topographie de la surface influençait de façon significative le taux d'adhésion des bactéries. En effet, les surfaces rugueuses n'ont pas inhibé l’adhésion de Salmonella enterica puisque le nombre de cellules adhérant à ces surfaces variait de 30 ± 4 à 65 ± 4 bactéries par champ microscopique. En revanche, un comportement anti-adhésif vis-à-vis de Salmonella enterica a été mis en évidence pour les surfaces plus lisses. En effet, le nombre de cellules attachées était proche de zéro sur ces revêtements. Une approche complémentaire à cette stratégie passive d'élaboration de surfaces anti-adhésives est le développement de surfaces actives. Les technologies émergentes de revêtements antimicrobiens actifs et efficaces permettent de relever le défi de l'élimination des biofilms pathogènes formés sur les matériaux utilisés dans les milieux hospitaliers et agroalimentaires. L'acier inoxydable est un matériau couramment utilisé dans ces domaines, mais il possède malheureusement des propriétés bio-fonctionnelles insuffisantes, ce qui le rend susceptible à l'adhésion bactérienne et au développement de biofilms. Dans ce contexte, cette thèse présente une revue des revêtements développés en employant des biocides et des peptides antimicrobiens (AMPs) greffés sur l'acier inoxydable. De plus, une nouvelle approche active basée sur l'acier inoxydable revêtu de nisine, un AMP commun accepté comme une alternative sûre pour prévenir le développement de biofilms pathogènes, est développée. Dans cette etude, des surfaces en acier inoxydable ont été fonctionnalisées par la nisine qui a été greffée à la surface soit via son groupe carboxylique ou via son groupe amino. En effet, les surfaces revêtues de nisine greffée via son groupe aminé ont montré une puissante activité antibactérienne tandis que la surface greffée avec la nisine liée par son groupe carboxyle n'a montré aucun effet antimicrobien. Les analyses des propriétés de surface ont permis de mieux comprendre les effets antibactériens, les caractéristiques chimiques et topographiques des surfaces traitées ainsi que la configuration et la quantification de la nisine
The operating environment in the food and medical fields allows bacteria to attach and grow on surfaces, resulting in the formation of pathogenic and resistant bacterial biofilms. These pathogenic structures are responsible for several foodborne illnesses and hospital-acquired infections. Therefore, to fight this public health scourge, one possible approach is the use of cold plasma technologies for the development of coatings on different materials. This work presents the different factors influencing bacterial adhesion to a substrate. In addition, strategies for the development of passive coatings to prevent biofilm formation by cold plasma surface treatments are described as well as the anti-adhesive properties of the developed surfaces. General aspects of coating, including physicochemical surface modifications and the use of cold plasma technologies, are also presented. In this context, a study was conducted to inhibit the adhesion of the pathogenic bacterium Salmonella enterica to the surface of stainless steel via cold plasma treatment. In order to limit the formation of Salmonella enterica biofilm, organosilicon coatings based on the monomer 1,1,3,3-tetramethyldisiloxane, mixed or not with oxygen, were elaborated by plasma polymerization with post-microwave nitrogen discharge. The effect of cold plasma parameters on coating properties, surface topography, and Salmonella enterica cell adhesion was studied. The results revealed that the surface topography significantly influenced the adhesion rate of bacteria. Indeed, rough surfaces did not inhibit Salmonella enterica adhesion as the number of cells adhering to these surfaces varied from 30 ± 4 to 65 ± 4 bacteria per microscopic field. On the other hand, an anti-adhesive behaviour towards Salmonella enterica was demonstrated for the smoother surfaces. Indeed, the number of attached cells was close to zero on these coatings. A complementary approach to this passive strategy of anti-adhesive surfaces is the development of active surfaces. Emerging technologies for effective active antimicrobial coatings are addressing the challenge of eliminating pathogenic biofilms formed on materials used in hospital and food processing environments. Stainless steel is a commonly used material in these fields, but unfortunately it has insufficient bio-functional properties, making it susceptible to bacterial adhesion and biofilm development. In this context, this thesis presents a review of coatings developed by employing biocides and antimicrobial peptides (AMPs) grafted onto stainless steel. In addition, a new active approach based on stainless steel coated with nisin, a common AMP accepted as a safe alternative to prevent the development of pathogenic biofilms, is developed. In this study, stainless steel surfaces were functionalized by nisin which was grafted to the surface either via its carboxyl group or via its amino group. Indeed, the surfaces coated with nisin grafted via its amino group showed a potent antibacterial activity while the surface grafted with nisin linked via its carboxyl group showed no antimicrobial effect. Analyses of the surface properties provided insight into the antibacterial effects, chemical and topographical characteristics of the treated surfaces, and the configuration and quantification of nisin
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Lund, Thomas Anthony. "Evading the anti-tumour immune response : a novel role for Focal Adhesion Kinase". Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25392.

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Here I describe a new function of Focal Adhesion Kinase (FAK) in driving anti-tumour immune evasion. The kinase activity of FAK in squamous cancer cells drives the recruitment of regulatory T-cells (Tregs) by transcriptionally regulating chemokine/cytokine and ligand-receptor networks, including the transcription of CCL5 and TGFβ, which are required for enhanced Treg recruitment. In turn, these changes inhibit antigen-primed cytotoxic CD8+ T-cell activity in the tumour microenvironment, permitting survival and growth of FAK-expressing tumours. I show that immune evasion requires FAK’s catalytic activity, and a small molecule FAK kinase inhibitor, VS-4718, which is currently in clinical development, drives depletion of Tregs and permits CD8+ T-cell-mediated tumour clearance. It is therefore likely that FAK inhibitors may trigger immune-mediated tumour regression, providing previously unrecognized therapeutic benefit.
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6

Sommer, Roman [Verfasser]. "Pseudomonas aeruginosa Lectin LecB as a Target in the Anti-Virulence Therapy : Towards Carbohydrate-based Anti-Adhesion Drugs / Roman Sommer". Konstanz : Bibliothek der Universität Konstanz, 2016. http://d-nb.info/1160876479/34.

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Othmani, Ahlem. "Médiation chimique entre l’algue brune méditerranéenne Taonia atomaria et la communauté bactérienne associée à sa surface". Thesis, Toulon, 2014. http://www.theses.fr/2014TOUL0001/document.

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Dans le milieu marin, toute surface immergée est rapidement colonisée par des bactéries, puis par d’autres micro-organismes, conduisant à la formation de structures tridimensionnelles complexes appelées biofilms. Cette étape est généralement suivie par l’installation de macro-colonisateurs. Néanmoins, un certain nombre d’organismes marins, tels que les macro-algues, présentent des surfaces peu épiphytées à l’échelle macroscopique. Des algues méditerranéennes (Taonia atomaria et Dictyota spp.) ont été sélectionnées dans le cadre de ces travaux de thèse pour leur capacité à conserver leur surface peu colonisée. Cependant, des observations de leurs surfaces par microscopie ont montré l’existence de biofilms diversifiés à la surface de leurs thalles. Le but de cette thèse est de mieux comprendre les mécanismes de médiation chimique entre ces algues et les bactéries associées à leur surface. La première partie de ce travail a été consacrée à l’étude du rôle de molécules d’origine algale vis-à-vis de l’adhésion de bactéries marines. Pour cela, la composition chimique totale des algues sélectionnées a été analysée conduisant à l’isolement et à la caractérisation structurale de 12 molécules, dont trois se sont révélées être originales. L’activité anti-adhésion de la majorité de ces composés a ensuite été évaluée : le 1-O-octadecenoylglycérol s’est avéré être le produit le plus actif (20 µM < CE50 <55 µM). La deuxième partie a été dédiée plus particulièrement à l’étude du métabolome de surface de T. atomaria dans le but d’évaluer son implication dans les interactions écologiques entre l’algue et les bactéries associées à sa surface. Un protocole d’obtention et d’analyse spécifique des extraits surfaciques a tout d’abord été développé. Ce protocole est basé sur le trempage des thalles dans des solvants organiques et un contrôle de l’intégrité des cellules membranaires des algues y est associé. L’échantillonnage a été effectué mensuellement à Carqueiranne (Nord-ouest de la Méditerranée, France) durant la période allant de février à juillet 2013. Les résultats obtenus montrent qu’un sesquiterpène est exprimé majoritairement à la surface de l’algue. Il a été démontré que ce composé inhibe l’adhésion de souches bactériennes de référence tout en restant inactif vis-à-vis de celles isolées à la surface de l’algue. Une telle spécificité n’a pas été observée ni dans le cas de biocides commerciaux, ni pour les autres métabolites produits par T. atomaria. Dans un second temps, un suivi saisonnier des extraits de surface ainsi que des communautés bactériennes associées a été effectué par métabolomique (LC-MS) et DGGE, respectivement. Des fluctuations saisonnières de ces deux paramètres ont été reportées sans mettre en évidence de corrélation évidente entre eux. La présence de la molécule majeure de surface durant tout le suivi saisonnier a été notée ainsi que sa capacité à diffuser dans l’eau de mer. Enfin, l’étude de l’implication potentielle des bactéries associées à T. atomaria dans le contrôle du biofilm a été entreprise en évaluant l’activité de leurs extraits vis-à-vis de l’adhésion de souches de référence. En conclusion, nous émettons l'hypothèse que T. atomaria pourraient contrôler partiellement le biofilm associé à sa surface en faisant intervenir des métabolites spécifiques
In the marine environment, all submerged surfaces are rapidly colonized by bacteria and other microorganisms, resulting in the formation of complex three-dimensional structures called biofilms. This step could be followed by the attachment of macro-colonizers. Nevertheless, a number of marine organisms, such as macro-algae, appeared to be relatively free of epibionts at a macroscopic scale. In this study, several Mediterranean algae (Taonia atomaria and Dictyota spp.) were selected for their ability to keep their surface free of biofouling. However, microscopic techniques allowed the observation of a diversified biofilm on the surface of their thalli. The purpose of this work was to understand how this alga could interact with its associated bacteria using a chemical ecological approach. The first part of this work deals with studying the anti-adhesion properties of algal molecules against a range of marine bacteria. For this, the whole chemical composition of the two algae was analyzed leading to the isolation and structural characterization of 12 molecules from which three were found to be new. The anti-adhesion activity of some of these compounds was then evaluated: 1-O-octadecenoylglycerol proved to be the most active product (20 µM < EC50 <55 µM). The second part of this study was dedicated to the study of the surface metabolome of T. atomaria in order to assess its involvement in the ecological interactions between the alga and its associated bacteria. A specific extraction protocol was optimized for the surface compounds using a dipping technique in organic solvents associated with the integrity control of algal cell membrane. Sampling was carried out monthly at Carqueiranne (N W Mediterranean Sea, France) between February and July 2013. The results showed the presence of a major molecule in accordance with a sesquiterpenic structure. Anti-adhesion capacity against reference bacterial strains was noticed for this compound, while it remained inactive against strains isolated from the algal surface. This specificity was not observed for commercial biocides and the other molecules purified from crude algal extracts of T. atomaria. Then, changes in surface extracts and associated bacterial surface communities were monitored using metabolomics (LC-MS) and DGGE, respectively. Seasonal fluctuations for the two parameters could be reported without any evident correlation between them. The occurrence of the major molecule throughout the seasonal monitoring was also noticed and its capacity to diffuse in the marine environment was shown. Finally, the study of the potential involvement of the associated bacteria in the biofilm control was conducted by evaluating the anti-adhesion activity of their crude extracts against reference strains. In conclusion, we hypothesize that T. atomaria could control at least partially the biofilm at its surface using specific metabolites
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8

Soon, D. "MRI evaluation of the anti-adhesion molecule antibody Natalizumab and the blood-brain barrier in Multiple Sclerosis". Thesis, University College London (University of London), 2010. http://discovery.ucl.ac.uk/19424/.

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As Blood-brain barrier (BBB) breakdown is central to inflammatory lesion formation, it presents a potential target in the formulation of putative therapeutic agents in MS. The action of natalizumab, a monoclonal antibody acting at the BBB, is investigated through a phase III monotherapy trial (AFFIRM) and associated substudies. Subtle BBB disruption from non-inflamed lesions, which could contribute to axonal damage through leakage of inflammatory cells and associated mediators into surrounding parenchyma, is also studied. Introductory chapters (1-3) provide a brief overview of MS, clinical trials, magnetic resonance imaging (MRI), the BBB and natalizumab. Chapter four describes MRI results of AFFIRM- a 2 year multi-centre trial involving 942 patients. Compared with placebo, natalizumab reduced number of gadolinium (Gd)- enhancing lesions by 92%, new/enlarging T2-hyperintense lesions by 83%, and new T1- hypointense lesions by 76%. Chapter five describes a 57 patient AFFIRM trial substudy in which the influence of natalizumab on segmental atrophy was investigated. Atrophy was predominant in grey matter (GM) and was independent of lesion load. Fluctuations in white matter (WM) volume followed changes in inflammatory lesion load. Atrophy was not influenced by natalizumab. The effect of natalizumab on subtle BBB disruption (inferred by measuring the post-Gd %change in T1 weighted signal intensity) is studied in chapter 6. This AFFIRM substudy involved 40 patients (27 on natalizumab, 13 on placebo.) Although subtle BBB leakage was consistently detected in non-visibly enhancing lesions, natalizumab did not influence the degree of leakage. Chapter 7 describes a cross-sectional study which utilised post-Gd change in R1 (1/T1) as a marker BBB leakage. 19 patients (10 RRMS, 9 SPMS) were involved in this study. The subtle leakage observed from non-visibly enhancing lesions was distinct from leakage from visibly enhancing lesions. This was sustained over 60 minutes, greater in smaller lesions and in size-adjusted T1 hypointense lesions.
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Garcia, Cédric. "Elaboration d'un dispositif médical contenant une association d'actifs naturels innovants dans le but de prévenir l'escarre". Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5501.

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Dans le cadre d’une hospitalisation, l’escarre est un souci majeur aussi bien pour le confort des patients que d’un point de vue économique. Le vieillissement de la population confronte de plus en plus le personnel soignant à la prévention et au traitement des escarres. La prophylaxie n’en est donc que plus essentielle dans les milieux hospitaliers. Force est de constater qu’il existe en la matière peu de produits spécialisés dont l’efficacité a été éprouvée. En partenariat avec le laboratoire RIVADIS, nous avons donc voulu élaborer un système galénique contenant une association d’actifs naturels innovants afin de prévenir l’escarre. Un état de l’art complet a été effectué sur la thématique des escarres afin d’en comprendre tous les facteurs de risques. Par la suite, une recherche approfondie a permis de sélectionner les plantes et molécules pouvant être utilisées comme actifs dans la prévention et/ou le traitement de cette pathologie. Notre attention s’est particulièrement attardée sur le pouvoir anti-inflammatoire, cicatrisant, antioxydant et anti-adhésion bactérienne de ces actifs. Les deux meilleurs actifs obtenus sont la pectine de pomme et l’extrait sec de Centella asiatica L., dont les résultats se sont avérés significatifs sur au moins trois propriétés recherchées. L’étude des effets combinés de ses deux actifs a même montré une synergie sur le pouvoir anti-adhésion bactérienne. Ils ont alors été incorporés sous forme galénique, de façon à rendre possible la réalisation d’un effleurage aussi facile que celui permis par les huiles déjà présentes sur le marché tout en autorisant l’incorporation d’actifs hydrophiles
In the case of a hospitalization, bedsores are a major issue regarding the comfort of the patient as well as economical reasons. Due to the aging population, the nurses are more and more confronted to prevention and treatment of bedsores. Thus, prevention is now considered as essential in hospitals. It must be noted that in matter of bedsores, there exist only a few specialized products which efficiency has been proved. Therefore, in association with RIVADIS Laboratory, we planed to work on a galenic formulation which contains a combination of innovative natural active. A complete compilation of specialized publications on this topic has been realized in order to fully understand all the risk factors. Then, thanks to an extensive research, we identified the plants and molecules that could be used as actives for the prevention and/or treatment of this pathology. We focused on their anti-inflammatory, healing, antioxidant and bacterial anti-adhesive properties. The two best actives thus obtained are apple pectin and dry Centella asiatica L. extract, they present significant results on at least three of the four wanted properties. Studying the combined effects of these two actives even showed a synergy on bacterial anti-adhesive property. They have then been incorporated in a galenic formulation that makes the massage as easy as the one allowed by already commercialised oils and enables the incorporation of hydrophilic actives
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Grimes, Kimberly D. "Design, synthesis, and evaluation of small molecules in the discovery of novel antimicrobial agents". View the abstract Download the full-text PDF version (on campus access only), 2008. http://etd.utmem.edu/ABSTRACTS/2008-021-GrimesK-index.html.

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Thesis (Ph.D.)--University of Tennessee Health Science Center, 2008.
Title from title page screen (viewed on September 4, 2008). Research advisor: Richard E. Lee, Ph.D. Document formatted into pages (xiii, 124 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 109-124).
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Libros sobre el tema "Anti-adhesion"

1

Kahane, Itzhak y Itzhak Ofek, eds. Toward Anti-Adhesion Therapy for Microbial Diseases. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9.

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Garratt, Alistair Neil. Integrin adhesion receptor triggering by the extracellular matrix and anti-integrin antibodies. Manchester: University of Manchester, 1995.

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G, Bazán Nicolás, Botting Jack H y Vane John R, eds. New targets in inflammation: Inhibitors of COX-2 or adhesion molecules : proceedings of a conference held on April 15-16, 1996, in New Orleans, USA, supported by an educational grant from Boehringer Ingelheim. Dordrecht: Kluwer Academic Publishers, 1996.

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P, Sawan Samuel y Manivannan Gurusamy 1960-, eds. Antimicrobial/anti-infective materials: Principles, applications and devices. Lancaster, Pa: Technomic Pub. Co., 2000.

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Itzhak, Kahane, Ofek Itzhak y Bat-Sheva Seminar Toward Anti-Adhesion Therapy of Microbial Diseases (1996 : Zikhron Ya'akov, Israel), eds. Toward anti-adhesion therapy for microbial diseases. New York: Plenum Press, 1996.

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Kahane, Itzahak. Toward Anti-Adhesion Therapy for Microbial Diseases. Springer, 2011.

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Ofek, Itzhak y Itzahak Kahane. Toward Anti-Adhesion Therapy for Microbial Diseases. Springer London, Limited, 2012.

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National Aeronautics and Space Administration (NASA) Staff. Anti-Adhesion Elastomer Seal Coatings for Ultraviolet and Atomic Oxygen Protection. Independently Published, 2019.

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(Editor), N. Bazan, Jack H. Botting (Editor) y Sir John R. Vane (Editor), eds. New Targets in Inflammation: Inhibitors of COX-2 or Adhesion Molecules. Springer, 1996.

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Bazan, N., Jack H. Botting y Sir John R. Vane. New Targets in Inflammation: Inhibitors of COX-2 or Adhesion Molecules Proceedings of a Conference Held on April 15-16, 1996, in New Orleans, USA, Supported by an Educational Grant from Boehringer Ingelheim. Springer London, Limited, 2012.

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Capítulos de libros sobre el tema "Anti-adhesion"

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Gilboa-Garber, Nechama. "Towards Anti- Pseudomonas Aeruginosa Adhesion Therapy". En Toward Anti-Adhesion Therapy for Microbial Diseases, 39–50. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_5.

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Bueno, Juan. "Anti-Adhesion Coating with Natural Products:". En Essential Oils and Nanotechnology for Treatment of Microbial Diseases, 209–20. Boca Raton, FL : CRC Press/Taylor & Francis Group, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315209241-10.

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Hasty, David L. y Harry S. Courtney. "Group A Streptococcal Adhesion". En Toward Anti-Adhesion Therapy for Microbial Diseases, 81–94. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_10.

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Wang, Qi, Sujan Singh, K. G. Taylor y R. J. Doyle. "Anti-Adhesins of Streptococcus Sobrinus". En Toward Anti-Adhesion Therapy for Microbial Diseases, 249–62. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_30.

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Brendler, Thomas y Gunter Haesaerts. "Cranberry Proanthocyanidins (PACs) in Bacterial Anti-Adhesion". En Natural Medicines, 237–60. Boca Raton : Taylor & Francis, [2019]: CRC Press, 2019. http://dx.doi.org/10.1201/9781315187853-13.

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Etzioni, Amos. "Adhesion Molecules in Leukocyte Endothelial Interaction". En Toward Anti-Adhesion Therapy for Microbial Diseases, 151–57. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_17.

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Oelschlaeger, T. A., J. Morschhäuser, C. Meier, C. Schipper y J. Hacker. "Adhesion and Invasion of Escherichia Coli". En Toward Anti-Adhesion Therapy for Microbial Diseases, 57–62. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_7.

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Barton, Randall W., Robert Rothlein, John Ksiazek y Charles Kennedy. "Role of Anti-Adhesion Monoclonal Antibodies in Rabbit Lung Inflammation". En Leukocyte Adhesion Molecules, 149–55. New York, NY: Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4612-3234-6_12.

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Segal, Esther. "Inhibitors of Candida Albicans Adhesion to Prevent Candidiasis". En Toward Anti-Adhesion Therapy for Microbial Diseases, 197–206. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_24.

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Sharon, Nathan. "Carbohydrate—Lectin Interactions in Infectious Disease". En Toward Anti-Adhesion Therapy for Microbial Diseases, 1–8. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_1.

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Actas de conferencias sobre el tema "Anti-adhesion"

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Kadowaki, S., K. Ohishi, T. Hata, T. Sano y S. Yasukawa. "Advanced anti-slip and anti-skid re-adhesion control considering air brake for electric train". En 2005 IEEE 11th European Conference on Power Electronics and Applications. IEEE, 2005. http://dx.doi.org/10.1109/epe.2005.219367.

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Kerr, Sheena C., Stephen D. Carrington, Michaela Wimmerova, Iwona Bucior, Joanne N. Engel y John V. Fahy. "Inhibiting Fucose Binding Lectins As An Anti-Adhesion And Anti-Infection Strategy For Pseudomonas Airway Infections". En American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2468.

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Hartani, Kada y Azeddine Draou. "Anti-skid Re-adhesion control based on BMC for electric vehicle". En 2013 IV International Conference on Power Engineering, Energy and Electrical Drives (POWERENG). IEEE, 2013. http://dx.doi.org/10.1109/powereng.2013.6635702.

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Koivuluoto, H., C. Stenroos, M. Kylmälahti y P. Vuoristo. "Anti-Icing Behaviour of Thermally Sprayed Polymer Coatings". En ITSC 2016, editado por A. Agarwal, G. Bolelli, A. Concustell, Y. C. Lau, A. McDonald, F. L. Toma, E. Turunen y C. A. Widener. DVS Media GmbH, 2016. http://dx.doi.org/10.31399/asm.cp.itsc2016p0018.

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Abstract This study evaluates the anti-icing properties of flame-sprayed polyethylene (PE) coatings. In laboratory scale icing tests, thermally sprayed polymer coatings showed low ice adhesion compared to metals such as aluminum and stainless steel. The ice adhesion of flame-sprayed PE coatings was found to be roughly seven times lower than that of bulk aluminium and five times lower than that of bulk stainless steel.
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Kargar, Mehdi, Jeff Saucke, Amrinder S. Nain y Bahareh Behkam. "Bioinspired Anti-Biofilm Surfaces Based on Topographical Cues". En ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80847.

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Adhesion of bacteria to surfaces is the starting point for formation of biofilms, which tend to be significantly less responsive to antibiotics and antimicrobial stressors, compared with planktonic bacteria. The physicochemical properties of natural anti-biofilm surfaces are being actively studied to develop bioinspired anti-biofilm strategies. It has been shown that –majority of natural anti-biofilm surfaces have well organized micro/nanoscale surfaces features [1]. The difficulties associated with the manufacturing of well-defined and controlled nano-textured surfaces and complexity of the behaviour of microorganisms interacting with engineered surfaces has limited rigorous quantitative study of the state of adhesion of fouling microorganisms to engineered surfaces. The work presented here aims to advance the current understanding of cell-textured surface interaction with the ultimate goal of developing an anti-biofilm design framework based on topographical cues.
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Zhang, Wei, Shaopeng Wu, Xu Huang y Jizhe Zhang. "Effect of different anti stripping measures on adhesion between granite and asphalt". En 2011 International Conference on Electric Technology and Civil Engineering (ICETCE). IEEE, 2011. http://dx.doi.org/10.1109/icetce.2011.5776116.

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He, Jing, Bingbing Dou, Changfan Zhang, Linfan Liu y Xiaofei Yin. "Anti-slip strategy of locomotives using improved adhesion characteristic curve slope method". En 2017 Chinese Automation Congress (CAC). IEEE, 2017. http://dx.doi.org/10.1109/cac.2017.8242885.

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Bottsford-Miller, Justin, Angela Sanguino, Duangmani Thanapprapasr, Chad V. Pecot, Rebecca L. Stone, Kurt Auger, Alpa M. Nick y Anil K. Sood. "Abstract LB-230: Enhancing anti-angiogenic therapy by blocking focal adhesion kinase". En Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-230.

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Yosuke Shimizu, Kiyoshi Ohishi, Takashi Sano, Shinobu Yasukawa y Takafumi Koseki. "Anti-slip re-adhesion control based on disturbance observer considering bogie vibration". En 2007 European Conference on Power Electronics and Applications. IEEE, 2007. http://dx.doi.org/10.1109/epe.2007.4417378.

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Tobar, Daniel, Sri Kambhampati, Thunyaluk Pojtanabuntoeng y Vincent P. Wallace. "Assessment of anti-corrosion coatings adhesion using terahertz time domain reflection spectroscopy". En 2023 48th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). IEEE, 2023. http://dx.doi.org/10.1109/irmmw-thz57677.2023.10299144.

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Informes sobre el tema "Anti-adhesion"

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Morrison, Mark y Joshuah Miron. Molecular-Based Analysis of Cellulose Binding Proteins Involved with Adherence to Cellulose by Ruminococcus albus. United States Department of Agriculture, noviembre de 2000. http://dx.doi.org/10.32747/2000.7695844.bard.

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At the beginning of this project, it was clear that R. albus adhered tightly to cellulose and its efficient degradation of this polysaccharide was dependent on micromolar concentrations of phenylacetic acid (PAA) and phenylpropionic acid (PPA). The objectives for our research were: i) to identify how many different kinds of cellulose binding proteins are produced by Ruminococcus albus; ii) to isolate and clone the genes encoding some of these proteins from the same bacterium; iii) to determine where these various proteins were located and; iv) quantify the relative importance of these proteins in affecting the rate and extent to which the bacterium becomes attached to cellulose. BARD support has facilitated a number of breakthroughs relevant to our fundamental understanding of the adhesion process. First, R. albus possesses multiple mechanisms for adhesion to cellulose. The P.I.'s laboratory has discovered a novel cellulose-binding protein (CbpC) that belongs to the Pil-protein family, and in particular, the type 4 fimbrial proteins. We have also obtained genetic and biochemical evidence demonstrating that, in addition to CbpC-mediated adhesion, R. albus also produces a cellulosome-like complex for adhesion. These breakthroughs resulted from the isolation (in Israel and the US) of spontaneously arising mutants of R. albus strains SY3 and 8, which were completely or partially defective in adhesion to cellulose, respectively. While the SY3 mutant strain was incapable of growth with cellulose as the sole carbon source, the strain 8 mutants showed varying abilities to degrade and grow with cellulose. Biochemical and gene cloning experiments have been used in Israel and the US, respectively, to identify what are believed to be key components of a cellulosome. This combination of cellulose adhesion mechanisms has not been identified previously in any bacterium. Second, differential display, reverse transcription polymerase chain reaction (DD RT-PCR) has been developed for use with R. albus. A major limitation to cellulose research has been the intractability of cellulolytic bacteria to genetic manipulation by techniques such as transposon mutagenesis and gene displacement. The P.I.'s successfully developed DD RT- PCR, which expanded the scope of our research beyond the original objectives of the project, and a subset of the transcripts conditionally expressed in response to PAA and PPA have been identified and characterized. Third, proteins immunochemically related to the CbpC protein of R. albus 8 are present in other R. albus strains and F. intestinalis, Western immunoblots have been used to examine additional strains of R. albus, as well as other cellulolytic bacteria of ruminant origin, for production of proteins immunochemically related to the CbpC protein. The results of these experiments showed that R. albus strains SY3, 7 and B199 all possess a protein of ~25 kDa which cross-reacts with polyclonal anti-CbpC antiserum. Several strains of Butyrivibrio fibrisolvens, Ruminococcus flavefaciens strains C- 94 and FD-1, and Fibrobacter succinogenes S85 produced no proteins that cross-react with the same antiserum. Surprisingly though, F. intestinalis strain DR7 does possess a protein(s) of relatively large molecular mass (~200 kDa) that was strongly cross-reactive with the anti- CbpC antiserum. Scientifically, our studies have helped expand the scope of our fundamental understanding of adhesion mechanisms in cellulose-degrading bacteria, and validated the use of RNA-based techniques to examine physiological responses in bacteria that are nor amenable to genetic manipulations. Because efficient fiber hydrolysis by many anaerobic bacteria requires both tight adhesion to substrate and a stable cellulosome, we believe our findings are also the first step in providing the resources needed to achieve our long-term goal of increasing fiber digestibility in animals.
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Wang, Hao, Milad Salemi, Jiaqi Chen, P. N. Balaguru, Jinhao Liang y Ning Xie. DTPH56-15H-CAP04L An Inorganic Composite Coating for Pipeline Rehabilitation and Corrosion Protection. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), diciembre de 2018. http://dx.doi.org/10.55274/r0011991.

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The project aims to address the need for an inorganic coating composite for corrosion protection of pipelines in an aggressive environment. The inorganic coating does not generate CO2 emission or volatile organic content (VOC). Inorganic coatings are frequently used in the construction industry as anti-corrosion coatings, which are effective, chemically inert, hard, and thermally stable. In this study, microfiber reinforcement and Nano-modification were used to improve the performance of the inorganic coating system. The research work integrates both laboratory testing and numerical simulations. The major tasks conducted are 1) development of an inorganic coating with Nano modification; 2) accelerated corrosion testing; 3) durability and adhesion strength testing; 4) shear testing of coating with carbon fiber reinforced polymer (CFRP), and 5) analytical study of composite repair system of the pipeline.
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