Literatura académica sobre el tema "B-acute lymphoblastic leukemia"

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Artículos de revistas sobre el tema "B-acute lymphoblastic leukemia"

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Juárez-Avendaño, Gerardo, Nuria Citlalli Luna-Silva, Euler Chargoy-Vivaldo, et al. "Poor Prognosis Biomolecular Factors Are Highly Frequent in Childhood Acute Leukemias From Oaxaca, Mexico." Technology in Cancer Research & Treatment 19 (January 1, 2020): 153303382092843. http://dx.doi.org/10.1177/1533033820928436.

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Objective: To investigate the cellular and molecular epidemiology of acute leukemias in vulnerable populations of children and adolescents in Oaxaca de Juarez, Mexico. Material and Methods: Descriptive, cross-sectional and retrospective study, conducted from 2014 to 2018 in which profiles of molecular and immunophenotypic aberrations were investigated in children and adolescents diagnosed with acute leukemia, by evaluating 28 molecular abnormalities by HemaVision-Q28 multiplex RT-PCR kit and standardized EuroFlow Immunophenotyping of bone marrow cells. Results: We included 218 patients, with 8
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Sugisaki, Manato, Kenji Imamura, Yukie Terasaki, et al. "Slowly progressing acute lymphoblastic leukemia with prolonged leukopenia." SAGE Open Medical Case Reports 11 (January 2023): 2050313X2311777. http://dx.doi.org/10.1177/2050313x231177758.

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Acute lymphoblastic leukemia is typically characterized by leukocytosis, resulting from the uncontrolled proliferation of malignant cells. However, we report an atypical case of acute lymphoblastic leukemia that presented with leukopenia and exhibited a protracted clinical course spanning 6 months. The patient, a 45-year-old female, initially presented to our hospital with recurrent fever and was found to have lymphoblasts in a hypoplastic bone marrow. Upon further investigation, the patient was diagnosed with B-cell lymphoblastic leukemia, not otherwise specified, based on cell surface antige
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Loghavi, Sanam, Jeffery L. Kutok, and Jeffrey L. Jorgensen. "B-Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma." American Journal of Clinical Pathology 144, no. 3 (2015): 393–410. http://dx.doi.org/10.1309/ajcpan7bh5dnywzb.

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Adamaki, Maria, Spiros Vlahopoulos, George I. Lambrou, Athanasios G. Papavassiliou, and Maria Moschovi. "Aberrant AML1 gene expression in the diagnosis of childhood leukemias not characterized by AML1-involved cytogenetic abnormalities." Tumor Biology 39, no. 3 (2017): 101042831769430. http://dx.doi.org/10.1177/1010428317694308.

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The AML1 ( acute myeloid leukemia 1) gene, a necessary prerequisite of embryonic hematopoiesis and a critical regulator of normal hematopoietic development, is one of the most frequently mutated genes in human leukemia, involving over 50 chromosome translocations and over 20 partner genes. In the few existing studies investigating AML1 gene expression in childhood leukemias, aberrant upregulation seems to specifically associate with AML1 translocations and amplifications. The aim of this study was to determine whether overexpression also extends to other leukemic subtypes than the ones karyoty
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Hurwitz, CA, MR Loken, ML Graham, et al. "Asynchronous antigen expression in B lineage acute lymphoblastic leukemia." Blood 72, no. 1 (1988): 299–307. http://dx.doi.org/10.1182/blood.v72.1.299.299.

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Abstract Cell surface phenotypes of 113 B lineage acute lymphocytic leukemia (ALL) cases, defined by the presence of HLA-DR and at least one B-cell- specific antigen (either CD19, CD20, or CD22), were compared with antigen-defined stages of normal B lymphocyte development. The cases were first evaluated for expression of HLA-DR, CD19, CD34, CD10, CD20, and CD22 by indirect one-color immunofluorescence. Pairwise comparisons of cell surface marker expression were performed for each leukemic sample: no correlations were observed for paired antigen expression on the leukemic samples using antigens
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Hurwitz, CA, MR Loken, ML Graham, et al. "Asynchronous antigen expression in B lineage acute lymphoblastic leukemia." Blood 72, no. 1 (1988): 299–307. http://dx.doi.org/10.1182/blood.v72.1.299.bloodjournal721299.

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Cell surface phenotypes of 113 B lineage acute lymphocytic leukemia (ALL) cases, defined by the presence of HLA-DR and at least one B-cell- specific antigen (either CD19, CD20, or CD22), were compared with antigen-defined stages of normal B lymphocyte development. The cases were first evaluated for expression of HLA-DR, CD19, CD34, CD10, CD20, and CD22 by indirect one-color immunofluorescence. Pairwise comparisons of cell surface marker expression were performed for each leukemic sample: no correlations were observed for paired antigen expression on the leukemic samples using antigens expresse
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Li, Shiyong, and Glen Lew. "Is B-Lineage Acute Lymphoblastic Leukemia With a Mature Phenotype and L1 Morphology a Precursor B-Lymphoblastic Leukemia/Lymphoma or Burkitt Leukemia/Lymphoma?" Archives of Pathology & Laboratory Medicine 127, no. 10 (2003): 1340–44. http://dx.doi.org/10.5858/2003-127-1340-iballw.

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Abstract Context.—B-lineage acute lymphoblastic leukemia (ALL) with a mature phenotype and L1 morphology is a rare condition that may pose a diagnostic and management challenge. Objective.—To report our experience with 2 such unusual cases of pediatric B-lineage ALL. Design.—Morphologic, immunophenotypic, and cytogenetic features of the leukemic blast cells were reviewed in conjunction with clinical and other laboratory findings. Results.—The leukemic blast cells in both cases were small to medium with scant basophilic cytoplasm and several small inconspicuous nucleoli, characteristic of L1 ly
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Buhring, HJ, I. Sures, B. Jallal, et al. "The receptor tyrosine kinase p185HER2 is expressed on a subset of B- lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia." Blood 86, no. 5 (1995): 1916–23. http://dx.doi.org/10.1182/blood.v86.5.1916.bloodjournal8651916.

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The class I receptor tyrosine kinase (RTK) HER2 is an oncoprotein that is frequently involved in the pathogenesis of tumors of epithelial origin. Here we report mRNA expression in peripheral blood and bone marrow cells from healthy donors in hematopoietic cell lines and leukemic blasts from patients with acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML), chronic lymphoblastic leukemia (CLL), and chronic myeloid leukemia (CML). However, cell surface expression of HER2 protein (p185HER2) was found exclusively on a subset of leukemic cells of the B-lymphoblastic lineage. p185H
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Silva, Alessandra Suelen Jardim, Gustavo Henrique de Medeiros Oliveira, Lenilton Silva DA Silva Júnior, et al. "Clinical Utility of Flow Cytometry Immunophenotyping in Acute Lymphoblastic Leukemia." Blood 136, Supplement 1 (2020): 8. http://dx.doi.org/10.1182/blood-2020-143281.

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The acute lymphoblastic leukemia (ALL) is a malignant disease of the immune system and hematologic characterized by accumulation of neoplastic B lymphoid precursors or T (lymphoblasts) in the bone marrow and / or peripheral blood. The diagnosis of these leukemias occurs by morphological classification of French-American-British (L1, L2 or L3) associated with features of immunological profile T or B cell malignancies, based on the expression profile of monoclonal antibodies (MoAb) directed against the antigens of cell differentiation by flow cytometry (FC). Several studies have shown that blast
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Khabirova, Eleonora, Laura Jardine, Tim H. H. Coorens, et al. "Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia." Nature Medicine 28, no. 4 (2022): 743–51. http://dx.doi.org/10.1038/s41591-022-01720-7.

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AbstractKMT2A-rearranged infant ALL is an aggressive childhood leukemia with poor prognosis. Here, we investigated the developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia (B-ALL) using bulk messenger RNA (mRNA) meta-analysis and examination of single lymphoblast transcriptomes against a developing bone marrow reference. KMT2A-rearranged infant B-ALL was uniquely dominated by an early lymphocyte precursor (ELP) state, whereas less adverse NUTM1-rearranged infant ALL demonstrated signals of later developing B cells, in line with most other childhood B-ALLs. We comp
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Tesis sobre el tema "B-acute lymphoblastic leukemia"

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Oliveira, Tiago M. "The importance of glycosylation in Acute Lymphoblastic Leukemia." Thesis, Griffith University, 2021. http://hdl.handle.net/10072/410463.

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Acute leukemias, such as acute lymphoblastic leukemia (ALL), are aggressive cancers characterized by the rapid proliferation of malignant hematopoietic cells. Throughout the last 60 years, childhood ALL’s long-term survival rates increased from less than 10% to more than 90%. Despite these improvements, certain subtypes remain hard to manage (e.g. mixed lineage leukemia, MLL-r), and even new therapies frequently fail. Therefore, identifying leukemia-cell restricted antigens in these ALL subtypes remains crucial in the quest to develop novel diagnostic tools and specific treatments. Traditional
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Besada, Rana Hany. "BiTEs and CAR-Ts : immunotherapy in childhood B-cell acute lymphoblastic leukemia." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/115699.

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Thesis: S.M., Massachusetts Institute of Technology, Department of Biology, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 18-21).<br>B-cell acute lymphoblastic leukemia is the most common pediatric cancer, responsible for the most cancer-related deaths in children. Advances in chemotherapy over the past half-century have steadily increased the remission and survival of children with B-cell acute lymphoblastic leukemia to nearly 90%. However, the problems of minimal residual disease and relapsed and refractory disease persist. Personalized, targete
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Morisot, Sebastien. "Détermination of the frequency of leukemia stem cells in childhood precursor B cell acute lymphoblastic leukemias." Paris 11, 2009. http://www.theses.fr/2009PA11T022.

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Soto-Feliciano, Yadira M. (Yadira Marie). "PHF6 is a novel regulator of B-cell identity in acute lymphoblastic leukemia." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/103165.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis. Vita.<br>Includes bibliographical references.<br>Mutations in the zinc finger gene PHF6 are seen in approximately 20% of adult T-cell acute lymphoblastic leukemias and 3% of adult acute myeloid leukemias. The notable absence of PHF6 mutations in B-cell lineage malignancies has led to the hypothesis that PH
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James, Alva Rani [Verfasser]. "LncRNAs signature defining major subtypes of B-cell acute lymphoblastic leukemia / Alva Rani James." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1189140330/34.

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Nicoletti, Simon. "Natural Killer Cells and Pre-B Acute Lymphoblastic Leukemia : Evidence for an Unconventional Cytotoxicity Pathway." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS383.

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Les cellules Natural Killer (NK) représentent une population de cellules innées lymphoïdes aux fonctions anti-infectieuses et antitumorales. Les leucémies aiguës lymphoblastiques pré-B (LAL pré-B) constituent le cancer de l’enfant le plus fréquent et ont été décrites comme résistantes à la cytotoxicité médiée par les NK bien que les bases moléculaires demeurent inconnues.L’objectif de ces travaux a été de caractériser cette résistance. En développant un essai de cytotoxicité par cytométrie en flux et en utilisant des cellules effectrices activées in vitro, nous avons établi la sensibilité reta
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Ueno, Hiroo. "Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263562.

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Sartor, Chiara <1988&gt. "Research of predictive biomarkers to anti-CD22 antibody-drug conjugate treatment in B-cell acute lymphoblastic leukemia." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2022. http://amsdottorato.unibo.it/10252/1/PhD%20thesis_Chiara%20Sartor_XXXIV%20ciclo.pdf.

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Background: The treatment of B-cell acute lymphoblastic leukemia (B-ALL) has been enriched by novel agents targeting surface markers CD19 and CD22. Inotuzumab ozogamicin (INO) is a CD22-calicheamicin conjugated monoclonal antibody approved in the setting of relapse/refractory (R/R) B-ALL able to induce a high rate of deep responses, not durable over time. Aims: This study aims to identify predictive biomarkers to INO treatment in B- ALL by flow cytometric analysis of CD22 expression and gene expression profile. Materials and methods: Firstly, the impact on patient outcome in 30 R/R B-ALL pa
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Auer, Franziska [Verfasser], Arndt [Gutachter] Borkhardt, and Hermann [Gutachter] Aberle. "Paired Box 5 (PAX5) in B cell precursor acute lymphoblastic leukemia / Franziska Auer ; Gutachter: Arndt Borkhardt, Hermann Aberle." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2017. http://d-nb.info/1123197628/34.

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Groeneveld-Krentz, Stefanie [Verfasser]. "The clinical relevance of aneuploidy in relapses of pediatric B-cell precursor acute lymphoblastic leukemia / Stefanie Groeneveld-Krentz." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2020. http://d-nb.info/1223927180/34.

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Libros sobre el tema "B-acute lymphoblastic leukemia"

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St-Denis, Emily Jean. The progression of precursor B cell acute lymphoblastic leukemia in murine models. 2005.

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Capítulos de libros sobre el tema "B-acute lymphoblastic leukemia"

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Fukano, Reiji. "Mature B-Cell Acute Lymphoblastic Leukemia." In Pediatric Acute Lymphoblastic Leukemia. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0548-5_8.

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Gastier-Foster, Julie M. "Precursor B-Cell Acute Lymphoblastic Leukemia." In Molecular Pathology Library. Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-5698-9_24.

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Gorczyca, Wojciech. "B-Cell Acute Lymphoblastic Leukemia/Lymphoma." In Flow Cytometry in Neoplastic Hematology, 4th ed. CRC Press, 2022. http://dx.doi.org/10.1201/9781003197935-17.

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Sandlund, John T. "Treatment of B-Cell Acute Lymphoblastic Leukemia." In Treatment of Acute Leukemias. Humana Press, 2003. https://doi.org/10.1007/978-1-59259-307-1_16.

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Patte, Catherine. "Treatment of B-Cell Acute Lymphoblastic Leukemia." In Treatment of Acute Leukemias. Humana Press, 2003. https://doi.org/10.1007/978-1-59259-307-1_15.

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Ghanem, Hady, Hagop Kantarjian, Nitin Jain, and Elias Jabbour. "Management of B-Cell Acute Lymphoblastic Leukemia." In Cancer Consult: Expertise for Clinical Practice. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118589199.ch3.

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Hogan, Laura E., Luke D. Maese, Keith J. August, and Jennifer L. McNeer. "Treatment of Pediatric B- and T-Cell Acute Lymphoblastic Leukemia." In Clinical Management of Acute Lymphoblastic Leukemia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85147-7_4.

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Roberts, Kathryn G., and Charles G. Mullighan. "Molecular Pathways and Targets in B-Cell Progenitor Acute Lymphoblastic Leukemia." In Clinical Management of Acute Lymphoblastic Leukemia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85147-7_1.

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Gorczyca, Wojciech. "B-Cell Acute Lymphoblastic Leukemia/Lymphoma (B-ALL/LBL)." In Atlas of Differential Diagnosis in Neoplastic Hematopathology, 4th ed. CRC Press, 2021. http://dx.doi.org/10.1201/9781003120445-40.

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Molina, John C., and Nirali N. Shah. "Monoclonal Antibody-Based Treatment and Other New Agents for B-Lineage Acute Lymphoblastic Leukemia." In Clinical Management of Acute Lymphoblastic Leukemia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85147-7_13.

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Actas de conferencias sobre el tema "B-acute lymphoblastic leukemia"

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Kamble, Aahash, Utkarsha Pacharaney, Nusrat Parveen, Shamim Akhtar, and Gouri Morankar. "Deep Learning-Based Automated Detection and Classification of B-cell Acute Lymphoblastic Leukemia." In 2024 2nd DMIHER International Conference on Artificial Intelligence in Healthcare, Education and Industry (IDICAIEI). IEEE, 2024. https://doi.org/10.1109/idicaiei61867.2024.10842706.

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Ain, N. U., A. Kainat, A. Hurera, and J. Bierenbaum. "Acute Adult B-lymphoblastic Leukemia Presenting as Hypercalcemia." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3389.

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Dobson, Stephanie M., Robert Vanner, Esmé Waanders, et al. "Abstract A25: Evolving functional heterogeneity in B-acute lymphoblastic leukemia." In Abstracts: Fourth AACR International Conference on Frontiers in Basic Cancer Research; October 23-26, 2015; Philadelphia, PA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.fbcr15-a25.

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Dobson, Stephanie M., Robert Vanner, Esmé Waanders, et al. "Abstract LB-341: Evolving functional heterogeneity in B-acute lymphoblastic leukemia." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-341.

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Kane, Shriya, Yali Ding, Chandrika Gowda, et al. "Abstract 2927: Targeted combination treatment for B-cell acute lymphoblastic leukemia." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-2927.

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Kazybay, B., M. N. Ferrao Blanco, O. Heidenreich, and J. H. Vormoor. "Characterization of the stromal microenvironment in B-cell Acute Lymphoblastic Leukemia." In 35. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1786593.

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Spinella, Jean-François, Virginie Saillour, Chantal Richer, et al. "Abstract 4335: The genomic landscape of childhood pre-B acute lymphoblastic leukemia." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4335.

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Zanetti, SR, T. Velazco-Hernandez, F. Gutierrez-Agüera, et al. "CD19 and CD22-directed biespecific CAR for B-cell Acute Lymphoblastic Leukemia." In 32. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1687121.

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Schröder, C. F., Ž. Antić, U. zur Stadt, et al. "Comprehensive molecular and clinical characterization of DUX4-rearranged B-acute lymphoblastic leukemia." In 34. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1768545.

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Liu, S., Q. Sun, K. M. Debatin, and L. H. Meyer. "Effective targeting of Wnt Signaling in B Cell Precursor Acute Lymphoblastic Leukemia." In 34. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1768528.

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