Literatura académica sobre el tema "BPGM"
Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros
Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "BPGM".
Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.
También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.
Artículos de revistas sobre el tema "BPGM"
1
Knee, Kelly M., Amey Barakat, Lindsay Tomlinson, Lila Ramaiah, Zane Wenzel, Brendon Kapinos, Youngwook Ahn et al. "Sickle Cell Disease Model Mice Lacking 2,3-Dpg Show Reduced RBC Sickling and Improvements in Markers of Hemolytic Anemia". Blood 136, Supplement 1 (5 de noviembre de 2020): 27–28. http://dx.doi.org/10.1182/blood-2020-142052.
Texto completoResumen
Sickle cell disease (SCD) is a severe genetic disorder caused by a mutation in hemoglobin (b6Glu-Val), which allows the mutant hemoglobin to assemble into long polymers when deoxygenated. Over time, these polymers build up and deform red blood cells, leading to hemolytic anemia, vaso-occlusion, and end organ damage. A number of recent therapies for SCD have focused on modulating the mutant hemoglobin directly, however, reduction or elimination of 2,3-DPG to reduce Hb S polymerization and RBC sickling has recently been proposed as a therapeutic strategy for SCD. Current clinical studies focus on activation of pyruvate kinase to reduce 2,3-DPG, however, direct targeting of the enzyme which produces 2,3-DPG; Bisphosphoglycerate Mutase (BPGM) may also be possible. In this study we evaluate the impact of elimination of 2,3-DPG on SCD pathology by complete knockout of BPGM in Townes model mice. Animals with complete knockout of BPGM (BPGM -/-) have no detectable 2,3-DPG, while animals that are heterozygous for BPGM (BPGM -/+) have 2,3-DPG levels comparable to Townes mice. Western Blot analysis confirms that BPGM -/- animals completely lack BPGM, while BPGM -/+ animals have BPGM levels that are nearly equivalent to Townes mice. As expected from the lack of 2,3-DPG, BPGM -/- animals have increased oxygen affinity, observed as a 39% decrease in p50 relative to Townes mice. Complete elimination of 2,3-DPG has significant effects on markers of hemolytic anemia in BPGM -/- mice. Mice lacking 2,3-DPG have a 60% increase in hemoglobin (3.7 g/dL), a 53% increase in red blood cell count, and a 29% increase in hematocrit relative to Townes mice. The BPGM -/- mice also have a 57% decrease in reticulocytes, and a 61% decrease in spleen weight relative to Townes animals, consistent with decreased extramedullary hematopoiesis. Consistent with the reduction in hemolysis, BPGM -/- animals had a 59% reduction in red blood cell sickling under robust hypoxic conditions. BPGM -/+ animals had hemoglobin, RBC, and hematocrit levels that were similar to Townes animals, and a similar degree of RBC sickling to Townes mice. Liver phenotype was similar across all variants, with areas of random necrosis observed in BPGM -/-, BPGM -/+ and Townes mice. Higher percentages of microcytic and/or hyperchromic RBCs were observed in BPGM -/- animals relative to BPGM -/+ or Townes animals. These results suggest that modulation of 2,3-DPG has a positive effect on RBC sickling and hemolytic anemia, which may have therapeutic benefits for SCD patients. However, the lack of improvement in organ damage suggests that modulation of 2,3-DPG alone may not be sufficient for complete elimination of SCD phenotypes, and further investigation of this therapeutic avenue may be necessary. Disclosures No relevant conflicts of interest to declare.
2
Aljahdali, Anfal S., Faik N. Musayev, John W. Burgner, Mohini S. Ghatge, Vibha Shekar, Yan Zhang, Abdelsattar M. Omar y Martin K. Safo. "Molecular insight into 2-phosphoglycolate activation of the phosphatase activity of bisphosphoglycerate mutase". Acta Crystallographica Section D Structural Biology 78, n.º 4 (11 de marzo de 2022): 472–82. http://dx.doi.org/10.1107/s2059798322001802.
Texto completoResumen
Bisphosphoglycerate mutase (BPGM) is an erythrocyte-specific multifunctional enzyme that is responsible for the regulation of 2,3-bisphosphoglycerate (2,3-BPG) in red blood cells through its synthase and phosphatase activities; the latter enzymatic function is stimulated by the endogenous activator 2-phosphoglycolate (2-PG). 2,3-BPG is a natural allosteric effector of hemoglobin (Hb) that is responsible for decreasing the affinity of Hb for oxygen to facilitate tissue oxygenation. Here, crystal structures of BPGM with 2-PG in the presence and absence of 3-phosphoglycerate are reported at 2.25 and 2.48 Å resolution, respectively. Structure analysis revealed a new binding site for 2-PG at the dimer interface for the first time, in addition to the expected active-site binding. Also, conformational non-equivalence of the two active sites was observed as one of the sites was found in an open conformation, with the residues at the active-site entrance, including Arg100, Arg116 and Arg117, and the C-terminus disordered. The kinetic result is consistent with the binding of 2-PG to an allosteric or noncatalytic site as well as the active site. This study paves the way for the rational targeting of BPGM for therapeutic purposes, especially for the treatment of sickle cell disease.
3
Qiang, Qingfen, Jeanne M. Manalo, Hong Sun, Yujin Zhang, Anren Song, Alexander Q. Wen, Y. Edward Wen et al. "Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming". PLOS Biology 19, n.º 6 (17 de junio de 2021): e3001239. http://dx.doi.org/10.1371/journal.pbio.3001239.
Texto completoResumen
Hypoxia drives aging and promotes age-related cognition and hearing functional decline. Despite the role of erythrocytes in oxygen (O2) transport, their role in the onset of aging and age-related cognitive decline and hearing loss (HL) remains undetermined. Recent studies revealed that signaling through the erythrocyte adenosine A2B receptor (ADORA2B) promotes O2 release to counteract hypoxia at high altitude. However, nothing is known about a role for erythrocyte ADORA2B in age-related functional decline. Here, we report that loss of murine erythrocyte–specific ADORA2B (eAdora2b−/−) accelerates early onset of age-related impairments in spatial learning, memory, and hearing ability. eAdora2b-/- mice display the early aging-like cellular and molecular features including the proliferation and activation of microglia and macrophages, elevation of pro-inflammatory cytokines, and attenuation of hypoxia-induced glycolytic gene expression to counteract hypoxia in the hippocampus (HIP), cortex, or cochlea. Hypoxia sufficiently accelerates early onset of cognitive and cochlear functional decline and inflammatory response in eAdora2b−/− mice. Mechanistically, erythrocyte ADORA2B-mediated activation of AMP-activated protein kinase (AMPK) and bisphosphoglycerate mutase (BPGM) promotes hypoxic and metabolic reprogramming to enhance production of 2,3-bisphosphoglycerate (2,3-BPG), an erythrocyte-specific metabolite triggering O2 delivery. Significantly, this finding led us to further discover that murine erythroblast ADORA2B and BPGM mRNA levels and erythrocyte BPGM activity are reduced during normal aging. Overall, we determined that erythrocyte ADORA2B–BPGM axis is a key component for anti-aging and anti-age–related functional decline.
4
Lemarchandel, V., V. Joulin, C. Valentin, R. Rosa, F. Galacteros, J. Rosa y M. Cohen- Solal. "Compound heterozygosity in a complete erythrocyte bisphosphoglycerate mutase deficiency". Blood 80, n.º 10 (15 de noviembre de 1992): 2643–49. http://dx.doi.org/10.1182/blood.v80.10.2643.2643.
Texto completoResumen
Abstract Erythrocyte bisphosphoglycerate mutase (BPGM) deficiency is a rare disease associated with a decrease in 2,3-diphosphoglycerate concentration. A complete BPGM deficiency was described in 1978 by Rosa et al (J Clin Invest 62:907, 1978) and was shown to be associated with 30% to 50% of an inactive enzyme detectable by specific antibodies and resulting from an 89 Arg-->Cys substitution. The propositus' three sisters exhibited the same phenotype, while his two children had an intermediate phenotype. Samples from the family were examined using polymerase chain reaction and allele-specific oligonucleotide hybridization and sequencing techniques. Amplification of erythrocyte total RNA from the propositus' sister around the 89 mutation indicated the presence of two forms of messenger RNAs, a major form with the 89 Arg-->Cys mutation and a minor form with a normal sequence. Sequence studies of the propositus' DNA samples indicated heterozygosity at locus 89 and another heterozygosity with the deletion of nucleotide C 205 or C 206. Therefore, the total BPGM deficiency results from a genetic compound with one allele coding for an inactive enzyme (mutation BPGM Creteil I) and the other bearing a frameshift mutation (mutation BPGM Creteil II). Examination of the propositus' two children indicated that they both inherited the BPGM Creteil I mutation.
5
Lemarchandel, V., V. Joulin, C. Valentin, R. Rosa, F. Galacteros, J. Rosa y M. Cohen- Solal. "Compound heterozygosity in a complete erythrocyte bisphosphoglycerate mutase deficiency". Blood 80, n.º 10 (15 de noviembre de 1992): 2643–49. http://dx.doi.org/10.1182/blood.v80.10.2643.bloodjournal80102643.
Texto completoResumen
Erythrocyte bisphosphoglycerate mutase (BPGM) deficiency is a rare disease associated with a decrease in 2,3-diphosphoglycerate concentration. A complete BPGM deficiency was described in 1978 by Rosa et al (J Clin Invest 62:907, 1978) and was shown to be associated with 30% to 50% of an inactive enzyme detectable by specific antibodies and resulting from an 89 Arg-->Cys substitution. The propositus' three sisters exhibited the same phenotype, while his two children had an intermediate phenotype. Samples from the family were examined using polymerase chain reaction and allele-specific oligonucleotide hybridization and sequencing techniques. Amplification of erythrocyte total RNA from the propositus' sister around the 89 mutation indicated the presence of two forms of messenger RNAs, a major form with the 89 Arg-->Cys mutation and a minor form with a normal sequence. Sequence studies of the propositus' DNA samples indicated heterozygosity at locus 89 and another heterozygosity with the deletion of nucleotide C 205 or C 206. Therefore, the total BPGM deficiency results from a genetic compound with one allele coding for an inactive enzyme (mutation BPGM Creteil I) and the other bearing a frameshift mutation (mutation BPGM Creteil II). Examination of the propositus' two children indicated that they both inherited the BPGM Creteil I mutation.
6
Luque, J., M. D. Delgado, P. Rodriguez-Horche, M. T. Company y M. Pinilla. "Bisphosphoglycerate mutase and pyruvate kinase activities during maturation of reticulocytes and ageing of erythrocytes". Bioscience Reports 7, n.º 2 (1 de febrero de 1987): 113–19. http://dx.doi.org/10.1007/bf01121874.
Texto completoResumen
An increase in bisphosphoglycerate mutase (BPGM) and a decrease in pyruvate kinase (PK), i.e. a decrease in PK/BPGM ratio, was observed in red cell populations from anemic rats containing 95% down to 3% reticulocytes in blood. Such a ratio has been used to study the fractionation of recticulocytes, according to their degree of maturation, after counter-current distribution of those cell populations in dextrahpoly (ethylene glycol) two-phase systems. When applying this procedure to the fractionation according to age of erythrocytes from normal rats, the decrease of PK with cellular age was observed without a significant variation in BPGM activity.
7
Yang Liu, Bin Wu, Hongxu Wang y Pengjiang Ma. "BPGM: A big graph mining tool". Tsinghua Science and Technology 19, n.º 1 (febrero de 2014): 33–38. http://dx.doi.org/10.1109/tst.2014.6733206.
Texto completo
8
Roberts, Bruce R., Chris Wolverton y Lauren Janowicz. "The impact of substrate and irrigation interval on the post-transplant root growth of container-grown zinnia and tomato1". Journal of Environmental Horticulture 35, n.º 1 (1 de marzo de 2017): 1–5. http://dx.doi.org/10.24266/0738-2898-35.1.1.
Texto completoResumen
Abstract Substrate type and irrigation interval were studied to determine their impact on the post-transplant root growth of ‘Thumbelina' zinnia (Zinnis elegans Jacq.) and ‘Celebrity Hybrid' tomato (Lycopersicon esculentum Mill.). Seeds of both species were planted in 80 cm3 (2.7 fl oz) plug cells containing either Metromix 360™ (MM360) or Ball Professional Growing Mix™ (BPGM) and, following germination, the seedlings were transplanted into 450 cm3 (27.5 in3) plastic pots containing the same substrate. Evapotranspiration (ETO) was measured gravimetrically each day and the water lost via ETO added back to the substrate at intervals of 24, 48 or 96hr. For zinnia, root growth was consistently better for seedlings grown in BPGM, a substrate with greater water holding capacity and air-filled porosity. For plants grown in BPGM and irrigated every 48hr, root dry weight was significantly greater than it was for any of the remaining treatments. For tomato, root growth was greater for seedlings grown in BPGM and for transplants irrigated at 96 hr intervals; but, unlike zinnia, no significant interactions between substrate type and irrigation interval were observed. The results of this study show that root growth of plug-grown transplants can be improved by selecting a substrate with high porosity that allows for optimum oxygen and water exchange, and by extending the irrigation cycle to 48 hr (zinnia) or 96 hr (tomato). Index words: irrigation scheduling, moisture stress, plant establishment, soilless growing media, transplant production Species used in this study: ‘Thumbelina' zinnia (Zinnia elegans Jacq.); ‘Celebrity Hybrid' (Lycopersicon esculentum Mill.).
9
Zhang, Jian, Chi Huang, Zehan Liu, Shuai Ren, Zilong Shen, Kecheng Han, Weiguang Xin, Guanyi He y Jianyu Liu. "Screening of Potential Biomarkers in the Peripheral Serum for Steroid-Induced Osteonecrosis of the Femoral Head Based on WGCNA and Machine Learning Algorithms". Disease Markers 2022 (10 de febrero de 2022): 1–17. http://dx.doi.org/10.1155/2022/2639470.
Texto completoResumen
Background. Steroid-induced osteonecrosis of the femoral head (SONFH) has produced a substantial burden of medical and social experience. However, the current diagnosis is still limited. Thus, this study is aimed at identifying potential biomarkers in the peripheral serum of patients with SONFH. Methods. The expression profile data of SONFH (number: GSE123568) was acquired from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) in SONFH were identified and used for weighted gene coexpression network analysis (WGCNA). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to investigate the biological functions. The protein-protein interaction (PPI) network and machine learning algorithms were employed to screen for potential biomarkers. Gene set enrichment analysis (GSEA), transcription factor (TF) enrichment analysis, and competing endogenous RNA (ceRNA) network were used to determine the biological functions and regulatory mechanisms of the potential biomarkers. Results. A total of 562 DEGs, including 318 upregulated and 244 downregulated genes, were identified between SONFH and control samples, and 94 target genes were screened based on WGCNA. Moreover, biological function analysis suggested that target genes were mainly involved in erythrocyte differentiation, homeostasis and development, and myeloid cell homeostasis and development. Furthermore, GYPA, TMCC2, and BPGM were identified as potential biomarkers in the peripheral serum of patients with SONFH based on machine learning algorithms and showed good diagnostic values. GSEA revealed that GYPA, TMCC2, and BPGM were mainly involved in immune-related biological processes (BPs) and signaling pathways. Finally, we found that GYPA might be regulated by hsa-miR-3137 and that BPGM might be regulated by hsa-miR-340-3p. Conclusion. GYPA, TMCC2, and BPGM are potential biomarkers in the peripheral serum of patients with SONFH and might affect SONFH by regulating erythrocytes and immunity.
10
Petousi, N., R. R. Copley, T. R. J. Lappin, S. E. Haggan, C. M. Bento, H. Cario, M. J. Percy et al. "Erythrocytosis associated with a novel missense mutation in the BPGM gene". Haematologica 99, n.º 10 (11 de julio de 2014): e201-e204. http://dx.doi.org/10.3324/haematol.2014.109306.
Texto completoTesis sobre el tema "BPGM"
1
MUGNAIONI, CAMILLA. "Bisphosphoglyceratemutase (BPGM): a central role in metabolism of proliferating cells". Doctoral thesis, Università di Siena, 2016. http://hdl.handle.net/11365/1008257.
Texto completoResumen
Many kind of cancer cells exploit glycolysis rather than oxidative phosphorylation for energy production even in the presence of oxygen. This kind of metabolism, although less efficient in terms of ATP production, generates high levels of glycolytic intermediates necessary to support the high biosynthetic flux of rapidly proliferating cells. . This mechanism is further enhanced in cancer cells by the expression of a particular form of pyruvate kinase -M2 (PKM2) which promote a low efficiency glycolysis (in terms or ATP production) and consequently an increase in the formation of biosynthetic metabolites. In this work we investigate the role of Bisphosphogliceratemutase (BPGM) an enzyme involved in the metabolic reprogramming of highly proliferating cancer cells. BPGM acts both as a mutase, converting the glycolytic intermediate 1,3-bisphosphoglycerate to 2,3-bisphosphoglycerate and as a phosphatase, converting the 1,3-bisphosphoglycerate to 3-phosphoglycerate. BPGM is an erythrocyte-specific enzyme but our real time PCR and western blotting experiments show its expression in many cancer cell lines and in proliferating primary human fibroblasts. BPGM silencing lead to a strong decrease of cell proliferation rate BPGM activity in cancer cell lead to the skipping of the first ATP production in the glycolytic pathway of glycolysis, causing an increase of glycolytic flux necessary to sustain the high rate of intermediates production needed for support cancer cells growth.
2
SANTANA, André Felipe Lemos. "BPMG – Um modelo conceitual para governança em BPM". Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/17696.
Texto completoResumen
Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-08-18T12:06:50Z
No. of bitstreams: 2
license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)
[BPMG] Santana_Tese - vFinal.pdf: 4399647 bytes, checksum: bf6190517d388436edf4bd95b245d442 (MD5)Made available in DSpace on 2016-08-18T12:06:51Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) [BPMG] Santana_Tese - vFinal.pdf: 4399647 bytes, checksum: bf6190517d388436edf4bd95b245d442 (MD5) Previous issue date: 2015-08-18
Governança em BPM (Busines Process Management) é um aspecto frequentemente apontado como fundamental para o sucesso efetivo do gerenciamento de processos de negócio nas organizações. Isso parece ser especialmente verdade no contexto do setor público, onde a eficiência, prestação de contas e transparência (três princípios básicos da governança) precisam ser coordenadas. No entanto, as abordagens de governança em BPM têm se caracterizado por apresentarem conceitos complexos e pouco precisos, com visões bastante variadas sobre o tema, e modelos em alto nível que oferecem pouca ajuda sobre como implementá-la. Além disso, há um número reduzido de trabalhos empíricos descrevendo relatos práticos de implementação de governança em BPM. Assim, há uma escassez de modelos detalhados e consistentes nos quais praticantes e pesquisadores possam se basear. À vista dessa necessidade, essa tese teve como objetivo desenvolver e avaliar um modelo conceitual para apoiar a implantação da governança em BPM, chamado Modelo BPMG. Inicialmente, foram realizados estudos de caso exploratórios para levantamento de barreiras e facilitadores que influenciavam a governança em BPM em organizações do setor público que conduziam iniciativas de BPM. Constatou-se que as organizações não compreendiam precisamente o que é a governança em BPM nem tratavam explicitamente questões relacionadas mesmo quando conduzindo projetos de BPM. O modelo BPMG foi construído numa abordagem de design-science research contemplando também a criação de uma ferramenta de software que implementou elementos do modelo visando sua aplicação numa organização do setor público. Tanto o Modelo BPMG quanto a ferramenta tiveram sua aplicabilidade avaliada por integrantes do escritório de processos da organização pesquisada e por especialistas em governança de diferentes organizações. O resultado da avaliação apontou que o Modelo BPMG ajudou os praticantes de BPM da organização a desenvolverem um entendimento mais preciso e compartilhado da governança em BPM e foi percebido como significativamente útil para guiar a implantação dessa governança na organização.
BPM (Business Process Management) Governance is an aspect often seen as critical to the success of BPM in organizations. This seems to be especially true for the public sector, where efficiency, accountability and transparency (three basic governance principles) must be coordinated. However, governance approaches in BPM have been characterized as complex and imprecise, with quite different views on the subject, in addition to macro level models that provide little help on how to implement it. Moreover, there is a small number of empirical papers describing practical reports on BPM governance. Therefore, there is a lack of consistent and detailed conceptual frameworks and concrete applications that researchers and practitioners can rely on to properly address BPM Governance. In light of such need, this thesis presents a conceptual model to support the implementation of governance in BPM, named BPMG Model. Initially, exploratory case studies were performed to identify barriers and facilitators that impact the deployment of BPM governance in public sector organizations conducting BPM initiatives. It was observed that studied organizations do not precisely understand the concept of BPM governance. The conception of the BPMG model adopted a design-science research approach and also encompassed the development of a software tool that implemented model elements. Both the BPMG Model and the software tool were evaluated by the members of a BPM Office from a Brazilian public organization and by a group of governance experts from different organizations. Evaluation results revealed that the BPMG Model and tool supported BPM practitioners of the organization to develop a more accurate and shared understanding of governance in BPM. In particular, the model was considered as significantly helpful for the implementation of governance principles in the organization.
3
FERREIRA, Fabio da Silva. "R-BPM: uma metodologia para gestão de riscos em iniciativas de BPM". Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/20057.
Texto completoResumen
Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-07-27T12:57:10Z
No. of bitstreams: 2
license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5)
Dissertacao_FabioFerreira_Digital.pdf: 2972458 bytes, checksum: f0d2fa1803fb21110efdc841f63933b1 (MD5)Made available in DSpace on 2017-07-27T12:57:10Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertacao_FabioFerreira_Digital.pdf: 2972458 bytes, checksum: f0d2fa1803fb21110efdc841f63933b1 (MD5) Previous issue date: 2016-07-01
Na busca por agilidade, economia e qualidade em seus processos, um número crescente de empresas tem adotado técnicas de Gerenciamento de Processos de Negócios (do original em inglês: Business Process Management - BPM), já que esta permite que a organização torne seus processos mais eficientes, com maior precisão, rapidez, flexibilidade e qualidade. No entanto, mesmo gerenciados, os processos podem enfrentar riscos que podem causar forte impacto sobre os objetivos da organização se estes riscos não forem gerenciados de forma apropriada. Como o gerenciamento de riscos demanda recursos e a execução de várias atividades (entrevistas, análises, reuniões etc.) que também são demandados pelo BPM, a integração destes dois campos tem sido tema de pesquisa frequente nos últimos anos. Um problema com os trabalhos existentes, no entanto, é que as atividades de gerenciamento de riscos propostas são aplicadas apenas a algumas fases do ciclo de vida BPM. Esta dissertação teve como objetivo construir e avaliar uma metodologia para realizar o gerenciamento de riscos em processos de negócios de forma integrada com o ciclo de vida BPM. A metodologia, chamada R-BPM, é composta por um conjunto de fases e uma ferramenta de apoio. Ela é inspirada na estrutura de gerenciamento de riscos do COSO (Committee of Sponsoring Organizations of the Treadway Commission) e foi construída através da abordagem de Design Science Research, que envolve um ciclo iterativo de construção e avaliação. Para avaliar a metodologia e a ferramenta de software construída para apoiá-la, foi realizado um estudo de caso em uma organização pública. Os artefatos foram avaliados através de grupos focais e surveys com especialistas da organização. Os resultados mostraram que a metodologia R-BPM, além de permitir que as atividades relacionadas à gestão de riscos sejam executadas em conjunto com o ciclo de vida BPM, permite também compartilhar a responsabilidade pelos riscos e fornecer melhores condições para os analistas e donos dos processos avaliá-los. Como a metodologia foi utilizada para resolver um problema do mundo real na organização estudada, esta pesquisa também contribuiu para a disseminação de conhecimento acadêmico para o mercado.
In search for agility, economy and quality in their processes, an increasing number of companies have adopted techniques of Business Process Management (BPM), as this allows the organization make its processes more efficient with greater precision, speed, flexibility and quality. However, even when managed, processes may face risks that can cause strong impact on the organization's goals if these risks are not managed appropriately. As risk management requires resources and the execution of many activities (interviews, analysis, meetings and so on) which are also demanded by BPM, the integration of these two fields has been a research theme frequent in recent years. A problem with existing works, however, is that the risk management activities proposed are applied only to some phases of the BPM lifecycle. This work aimed to construct and evaluate a methodology to manage risks of business processes integrated with the BPM lifecycle. The methodology, called R-BPM, is composed of a set of phases and a supporting tool. It is inspired by the COSO (Committee of Sponsoring Organizations of the Treadway Commission) risk management structure and was built by Design Science Research strategy, which involves an iterative cycle of construction and evaluation. To evaluate the methodology and the software tool built to support it, we conducted a case study in a public organization. The artifacts were assessed through focus groups and surveys with the organization's experts. The results showed that the R-BPM allows the activities related to risk management can now be implemented together with the BPM lifecycle, as well as shares responsibility for the risks and provides better conditions for process owners evaluate them. As the methodology was used to solve a real-world problem in the organization studied, this research also contributed to the dissemination of academic knowledge to market.
4
BARRETO, Gleidson Antonio da Silva Sá. "C-BPM: uma metodologia para gestão de mudanças em iniciativas de BPM". Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/21051.
Texto completoResumen
Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-08-31T12:20:58Z
No. of bitstreams: 2
license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5)
Dissertação GASSB.pdf: 1938389 bytes, checksum: 666ea312a4f061c72152bab47ea872d4 (MD5)Made available in DSpace on 2017-08-31T12:20:58Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação GASSB.pdf: 1938389 bytes, checksum: 666ea312a4f061c72152bab47ea872d4 (MD5) Previous issue date: 2016-07-01
As iniciativas de BPM (Business Process Management) exigem mudanças no ambiente de negócios, com impactos significativos na cultura corporativa. Por isso, a Gestão de Mudanças é uma estratégia organizacional que deve ser incluída em iniciativas de BPM, para apoiar a organização para a realização dos objetivos estratégicos e maximizar o estado de prontidão para as mudanças. Entretanto, na academia e nas empresas há ausência de metodologias que abordem, de forma detalhada e consistente, a Gestão de Mudanças integrada ao ciclo de Gerenciamento de Processos de Negócio. Nesse contexto, esta pesquisa propõe uma metodologia de Gestão de Mudanças alinhada com o ciclo de vida de BPM, chamada Metodologia C-BPM (do inglês, Change – Business Process Management). A metodologia proposta baseia-se no guia do PMI (Project Management Institute) denominado “Managing Change in Organizations: A Pratice Guide”, e na abordagem proposta por John P. Kotter denominada “Kotter’s 8-Step Process for Leading Change”. Com base nessas referências, foram elaborados fluxos de ações ordenados que integram práticas de comunicação e capacitação às diretrizes gerais de Gestão de Mudanças e aos princípios de BPM. A metodologia C-BPM teve sua aplicabilidade avaliada por meio de um estudo de caso exploratório, realizado em uma organização pública que está conduzindo uma iniciativa de BPM. Para a coleta dos dados foram realizados grupos focais e uma pesquisa survey de natureza qualitativa, com a participação de especialistas em Gerenciamento de Processos de Negócio. Como resultado da avaliação, constatou-se que a metodologia C-BPM apresenta características relevantes para o aperfeiçoamento do gerenciamento das iniciativas de BPM, favorecendo o estabelecimento de uma cultura organizacional de aceitação das mudanças. Apesar dos resultados não serem generalizados para qualquer tipo de organização, esta pesquisa pode servir como referência para novos estudos empíricos nessa área de conhecimento.
Business Process Management (BPM) initiatives require changes in the organizational environment, with significant impacts on corporate culture. Therefore, Change Management is an organizational strategy that must be included in BPM initiatives to support the organization to achieve the strategic objectives and maximize the readiness state for change. However, in academia and companies, there are no methodologies that address the Change Management integrated with the Business Process Management cycle. That context, this research proposes a Change Management methodology aligned with the BPM lifecycle, called C-BPM Methodology (English, Change - Business Process Management). The proposed methodology is based on the PMI guide (Project Management Institute) called "Managing Change in Organizations: A Practice Guide," and the approach proposed by John P. Kotter called "Kotter's 8-Step Process for Leading Change." Based on these references, actions were proposed that integrate communication and training practices to the general guidelines of change management and BPM principles. The applicability of the C-BPM methodology was evaluated through an exploratory case study in a public organization that is leading a BPM initiative. To data collect, we conducted focus groups and a survey of qualitative research, with the participation of specialists in Business Process Management. As a result of the evaluation, it was found that C-BPM methodology propound relevant characteristics to improving the management of BPM initiatives, favoring the establishment of an organizational culture that accepts changes. Although the results are not generalizable to any type of organization, this research can serve as a reference for further studies in this area of expertise.
5
OLIVEIRA, Liliane Almeida Medeiros de. "IMM-BPM: um guia para a instanciação de um modelo de maturidade em BPM". Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/24524.
Texto completoResumen
Submitted by Alice Araujo (alice.caraujo@ufpe.br) on 2018-05-02T21:53:37Z
No. of bitstreams: 1
DISSERTAÇÃO Liliane Almeida Medeiros de Oliveira.pdf: 2366403 bytes, checksum: 986e936872ac02a02d89ec1aecbcb5a3 (MD5)Made available in DSpace on 2018-05-02T21:53:37Z (GMT). No. of bitstreams: 1 DISSERTAÇÃO Liliane Almeida Medeiros de Oliveira.pdf: 2366403 bytes, checksum: 986e936872ac02a02d89ec1aecbcb5a3 (MD5) Previous issue date: 2016-08-16
A Gestão de Processos de Negócios (Business Process Management - BPM) apoia organizações na melhoria contínua de seus processos. Para uma evolução consistente das iniciativas de BPM é importante a utilização de modelos de maturidade que direcionem as ações institucionais.Um bom modelo de maturidade deve disponibilizar ferramentas que avaliem as fraquezas e forças organizacionaise viabilizem melhorias. Os estudos realizados nesta pesquisa sugerem que a instanciação de modelos de maturidade em uma organização não é tarefa simples. É uma atividade complexa e que requer um planejamento e execução de passos eficazes. Uma das maiores dificuldades encontra-se no fato de que a maioria dos modelos disponibilizados não apresenta exemplos práticos de como foram instanciados. Assim, propomos o desenvolvimento de um guia para a instanciação de um modelo de maturidade em BPM, denominado IMM-BPM, estruturadoemtrêsfasessistemáticas que especificam atividades a serem executadas para que um modelo de maturidade possa ser efetivamente instanciado e implementado.O guia é baseado no modelo proposto por Rosemann e de Bruin (2005) efoi construído utilizando a abordagem de Design-Science Researchcombinada com o método de pesquisa de Estudo de Caso. O estudo teve como objetivo instanciaro modelo de maturidade BPM em uma organização do setor público e refinar o guia a partir das lições apreendidas com a instanciação.Foram realizados vários ciclos de melhorias incrementais no artefato, para que se pudesse obter o resultado esperado, ou seja, o desenvolvimento final do guia IMM-BPM. Além disso, sua aplicabilidade foi avaliada por meio de um survey com especialistas em BPM. Como resultado da avaliação, constatou-se que o Guia IMM-BPM é útil e facilita a instanciação de um modelo de maturidade BPM, contribuindo para a construção de uma cultura evolutiva das iniciativas de gestão de processos de negócios.
The BPM (Business Process Management) discipline aims to support organizations in the continuous improvement of business processes. In order to help the consistent evolution of BPM initiatives, it is important that organizations adopt maturity models to direct their future actions. A good maturity model must provide tools to evaluate the organizational strengths and weaknesses, support improvements and allow comparison with other organizations. The studies in this research suggest that the development of maturity models is not a simple task. The choice of an appropriate model is a complex activity that requires effictive planning. A major difficulty lies in the fact that most models available in the literature are not sufficiently tested or do not present practical and easily reproducible examples. In this research, it's proposed a guide for instantiation of BPM maturity models. The guide is called IMM-BPM and is structured in three systematic steps that specify activities that would be performed so that a maturity model can be effectively implemented and instantiated. The guide is based on the model proposed by Rosemann, de Bruin (2005) and was built using an approach of Design-Science Research combined with a Case Study Research. This research aimed, with the IMM-BPM, to instantiate a BPM maturity model in a public sector organization and to refine this guide with the lessons learned. We carried out several cycles of incremental improvements in the guide until get the desired results. In addition, its applicability was assessed through asurvey with BPM experts. As a result of the evaluation, it was found that the IMM-BPM guide is useful and facilitates the development of BPM maturity models, contributing to the construction of a culture that supports the evolution of BPM initiatives.
6
Ahmadian, Zahra. "Performance analysis of IEEE 802.15.4a BPSK/BPPM UWB transmission". Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31506.
Texto completoResumen
The ultra-wideband (UWB) technology has recently attracted considerable attention
in industry and academia. This is due to the great potentials of the license exempt
operation with UWB signals. These include high data. rate, low power consumption,
robustness to multipath propagation, good penetration properties and the ability for
accurate localization and ranging.
The IEEE working group 802.15 set up two task groups (TGs) for the standardization
of UWB physical layers for short-range communication: the IEEE T G 802.15.3a for
high data-rate transmission which was officially formed in December 2007 and the
IEEE TG 802.154a for low data-rate that became an official task group in March
2004. While the TG 802.15.3a did not succeed and was finally disbanded in January
2006; the TG 802.15.4a approved a draft standard in March 2007. This standard
prescribes a rather unique coding and modulation scheme, namely the concatenation
of an outer Reed-Solomon and an inner convolutional encoder with a mixed binary
phase-shift keying and pulse position modulation (BPSK/BPPM) and time-varying
spreading and position hopping. The decoding for and performance analysis of this
coding and modulation scheme are the subjects of this thesis.
First, we study the inner convolutional coded BPSK/BPPM in isolation. We suggest an
optimal symbol-wise decoding metric, which replaces the sub-optimal bit-wise metric
previously suggested in standardization documents, and we define semi-analytical ex- pressions for the bit-error rate (BER) performance with both optimal and sub-optimal
decoding metrics. It is shown through analytical and simulated results that, using
the optimal symbol-wise metric results in significant performance gains, of e.g. 2 dB
at BER of 10‾³. while decoding complexity is identical to that with bit-wise decoding
metric. Based on our semi-analytical results, we also quantify the performance loss due
to RAKE combining with a limited number of fingers as opposed to ideal combining.
Next, we investigate the entire concatenated coded BPSK/BPPM scheme, including the
outer RS code and the inner convolutional code, and we suggest an improved decoding
scheme by introducing reliability information generated by the inner decoder. More
specifically, two different soft output Viterbi algorithms (SOVA) are considered and
compared for generation of reliability information. For the conventional setup of inner
Viterbi and outer RS decoder, we define semi-analytical expressions for the frame-error
rate (FER) of the overall system, these expressions are highly valuable for quick
performance assessment, since simulating the system's performance is extremely time
consuming.
In addition to decoding assuming perfect channel state information at the receiver
(coherent receiver) considered so far, we also study the performance of decoding without
channel state information (non-coherent receiver) to detect the BPPM data bit. This
decoding mode is explicitly envisioned by the standard. Again, analytical expressions
for BER. and FER are obtained, and the performance of non-coherent and coherent
receivers are compared.Applied Science, Faculty of
Electrical and Computer Engineering, Department of
Graduate
7
Zikmund, Martin. "Interconnection between BPM and BI products". Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-12367.
Texto completoResumen
Interconnection between various types of IT systems used in an enterprise is crucial in these days. Most of companies are using many different kinds of applications in their daily running of the enterprise which leads to necessity of sharing data across those applications to enable all employees to make a right decision upon correct information. In my diploma thesis I deal with interconnection of two systems -- Business Process Management (BPM) and Business Intelligence (BI). Both systems belong to group of top IT systems with big influence on ongoing business and right decision making on all levels from operational to strategic. My paper contains theoretical as well as practical part of the solution for interconnection of BI and BPM systems. First part is about presenting and describing basic concepts and technologies which are used in process of integration of BI and BPM. At the beginning there is a short introduction to BPM, BI and SOA. Following part is including analysis of three major ways of interconnection between BI and BPM systems. Last part of the first theoretical section presents two products. IBM FileNet P8 representative of BPM system and IBM Cognos 8 BI as a representative of BI system. Second part deals with the practical example of real integration between BI and BPM systems. In first part of this section is simple description of the scenario -- business case. After that there is a detail depiction of two different kinds of integration of BI and BPM. Analysis of benefits, advantages and further possibilities are at the end of work.
8
Silveira, Neto João Leonardo. "Qualidade de ferramentas BPM (BPMS) e avaliação da abordagem business process management (BPM) em processos de software". Universidade de Fortaleza, 2013. http://dspace.unifor.br/handle/tede/92081.
Texto completoResumen
Made available in DSpace on 2019-03-29T23:42:14Z (GMT). No. of bitstreams: 0
Previous issue date: 2013-12-20Increasingly companies are using Business Process Management (BPM) tools as an alternative for modeling business processes. However, many of these tools include only part of the life cycle BPM or in unsatisfactory and required characteristics. In order to capture essential features for BPM Tools, this paper identifies and analyzes the characteristics and the quality factors of greatest importance. The list of features is based on guidelines of ISO/IEC 25000 standard and was evaluated by professional results were obtained by a survey. In the second part of this work we developed a structured interview consisting of questions about the use of BPM to support the Software Process focusing on the goals, gains, difficulties encountered, used tools, skills and behavior of professional Information Technology (IT) and relationship between software processes and organizational processes. The interview was administered to professionals who already have experience with BPM in TI. From the information obtained qualitative investigations were performed using the Grounded Theory method to seek conclusions about the relationship between BPM and Software Processes. The analysis of these results is evidence for a suitable choice of BPM Tools (BPMS) as well as some findings on the use of BPM as supporting software processes. Keywords: BPM, Business Process Management, Software Quality, Software Product Quality, Software Process.
Cada vez mais as empresas estão utilizando ferramentas de Business Process Management (BPM) como alternativa para a modelagem de processos de negócio. Apesar disso, muitas destas ferramentas abrangem somente parte do ciclo de vida BPM ou não apresentam características satisfatórias e necessárias. A fim de capturar características imprescindíveis para ferramentas BPM, este trabalho identifica e analisa as características e os fatores de qualidade de maior importância. A listagem de características foi baseada em diretrizes da norma ISO/IEC 25000 e foi avaliada por profissionais cujos resultados foram obtidos por meio de uma survey. Na segunda parte do trabalho foi desenvolvida uma entrevista estruturada composta por questionamentos sobre a utilização de BPM como apoio a Processos de Software focando nos objetivos, ganhos obtidos, dificuldades encontradas, ferramentas utilizadas, habilidades e comportamento dos profissionais de Tecnologia da Informação (TI) e a relação entre processos de software e processos organizacionais. A entrevista foi aplicada a profissionais que já possuem experiência com BPM na área de TI. A partir das informações obtidas foram realizadas investigações qualitativas utilizando o método Grounded Theory para buscar conclusões a cerca da relação entre BPM e Processos de Software. A análise desses resultados representa indícios para uma escolha adequada de ferramentas de BPM (BPMS) como também algumas conclusões sobre a utilização de BPM como apoio a processos de software. Palavras chave: BPM, Business Process Management, Qualidade de Software, Qualidade de Produto de Software, Processo de Software.
9
Bettiol, Rafael Tiburi. "Efetiva transformação com gestão de processos de negócios – BPM". Universidade do Vale do Rio dos Sinos, 2016. http://www.repositorio.jesuita.org.br/handle/UNISINOS/6328.
Texto completoResumen
Submitted by JOSIANE SANTOS DE OLIVEIRA (josianeso) on 2017-06-06T13:04:42Z
No. of bitstreams: 1
Rafael Tiburi Bettiol_.pdf: 3696012 bytes, checksum: 981a8a497c8c80c028d42c364106eda3 (MD5)Made available in DSpace on 2017-06-06T13:04:42Z (GMT). No. of bitstreams: 1 Rafael Tiburi Bettiol_.pdf: 3696012 bytes, checksum: 981a8a497c8c80c028d42c364106eda3 (MD5) Previous issue date: 2016-06-27
Nenhuma
A Gestão de Processos de Negócio (BPM) vem sendo adotada pelas organizações a fim de solucionar problemas latentes nas interações das atividades organizacionais, proporcionando assim, maior eficiência operacional e melhores níveis de serviço, os quais satisfarão e melhorarão a experiência dos clientes para com os produtos e serviços. Para essa adoção, os processos de negócio passam por projetos de BPM, os quais tem o objetivo de entender como uma determinada etapa da organização atua, eliminando desperdícios, e redesenhar o processo aderindo à melhores práticas e à novos conceitos. Após essas fases de projeto, são estabelecidas ações que irão transformar o processo de negócio do estado atual ao futuro. É neste contexto de pós projeto que este estudo de casos busca analisar o “por que” e o “como” os processos de negócio efetivamente transformaram. O “por que” está na análise das variáveis que influenciam a efetiva transformação, sendo que as variáveis estão baseadas em conceitos de Rotinização, Infusão e Mudança Cultural. E o “como” está baseado nos projetos de BPM, suas técnicas, métodos, ferramentas e entregáveis, estabelecendo padrões de condução. Na execução desta pesquisa, foram efetuadas pesquisas bibliográficas para estabelecer os principais conceitos, possibilitando definições claras das variáveis envolvidas. A pesquisa foi baseada em um estudo de múltiplos casos através das técnicas de coleta de dados entrevista e dados secundários. Foram efetuadas validações dos conceitos, das variáveis, das perguntas e do roteiro de entrevista junto a especialistas empregando Focus Group. Após a validação do instrumento de pesquisa, as entrevistas foram realizadas com organizações que haviam executado projetos de BPM e os respectivos processos estivessem em operação no instante da pesquisa. A coleta de dados, junto com os dados secundários, obteve informações suficientes para a segmentação, codificação e análise. Na análise, para medir a efetiva transformação, foram estabelecidos níveis de influência, negativo, neutro e positivo, para cada variável. Sendo assim, a efetiva transformação dos processos de negócio pôde ser analisada através da composição das influências das variáveis, uso prolongado, uso na integração, orçamento, equipe, capacitação, governança corporativa, fornecimento e manutenção, atitudes individuais para com a mudança e compartilhamento de conhecimento. O resultado do estudo demonstra que a variável uso prolongado foi a que mais influenciou negativamente a efetiva transformação dos casos analisados e, por outro lado, a variável governança corporativa foi a que mais influenciou positivamente. Na análise dos padrões de condução através das técnicas, métodos, ferramentas e entregáveis utilizados nos respectivos projetos de BPM, foi utilizada uma análise chamada de Densidade de Código. A partir dessa 5 densidade pôde-se verificar que Brainstorming, BPMN e Entrevistas são as mais utilizadas dentre as técnicas, métodos, ferramentas e entregáveis dos casos analisados. Portanto, essas análises geraram conteúdo para discussões que se estenderam desde os facilitadores e barreiras para a efetiva transformação, passando por um paralelo entre a efetiva transformação conceitual e a observada, até as técnicas, métodos, ferramentas e entregáveis que mais foram utilizadas.
The Business Process Management (BPM) has been adopted by organizations to solve potential problems in the interactions of organizational activities, thus providing greater operational efficiency and improved service levels, which meet and improve the customer experience toward products and services. For this adoption, business processes undergo BPM projects, which aims to understand how a certain stage of organization operates, eliminating waste, and redesigning the process adhering to best practices and new concepts. After these project phases, actions are established that will transform the business process from the current state to the future. It is in this context of post project that this study of cases aims to analyze the "why" and "how" business processes effectively transformed. The "why" is the analysis of the variables that influence the effective transformation, and the variables are based on concepts of Routinization, Infusion and Cultural Change. And the "how" is based on BPM projects, their techniques, methods, tools and deliverables, setting leading standards. In the execution of this research, literature searches were performed to establish the main concepts, enabling clear definitions of the variables involved. The research was based on a multiple case study through interview data collection techniques and secondary data. The concepts, variables, questions and interview guide were validated with experts using Focus Group. After validation of the research instrument, interviews were conducted with organizations that had implemented BPM projects and their processes were in operation at the instant of the research. The data collection, along with the secondary data, obtained enough information for segmentation, coding and analysis. In the analysis, to measure the effective transformation, were established levels of influence, negative, neutral and positive, for each variable. Thus, the effective transformation of business processes could be analyzed through the composition of the influences of variables, extended use, use in integration, budget, staff, training, corporate governance, supply and maintenance, individual attitudes towards change and sharing knowledge. The result of the study shows that extended use variable was the most negatively influenced the effective transformation of the cases and, on the other hand, the variable corporate governance was the most influenced positively. In the analysis of leading patterns through the techniques, methods, tools and deliverables used in their BPM projects, a analysis called code density was used. From this density could be seen that Brainstorming, BPMN and Interviews are the most used among the techniques, methods, tools and deliverables of the cases. Therefore, these analyzes generated content for discussions that extended from the facilitators and barriers to effective transformation, through a parallel 7 between the conceptual and observed effective transformation until the techniques, methods, tools and deliverables that more were used.
10
González, Guerrero Daniel Carlos. "Desarrollo de un plan de negocios para proveer BPM como un servicio (BPMaaS) o BPM en la nube". Tesis, Universidad de Chile, 2014. http://www.repositorio.uchile.cl/handle/2250/116617.
Texto completoResumen
Magíster en Gestión y Dirección de EmpresasLas organizaciones hoy más que nunca, por la globalización y mercados competitivos, necesitan ser más rápidas, flexibles y eficientes para enfrentar las demandas del mercado, clientes, proveedores, reguladores, entre otras. Para ello deben tener la capacidad de rediseñar y optimizar sus procesos de manera continua, necesitando prácticas, metodologías y herramientas que les permitan mantenerse vigentes. En este contexto, es que BPM o Administración de Procesos de Negocio, juega una labor crucial para lograr los nuevos desafíos. Siendo BPM una disciplina integradora que engloba técnicas y disciplinas, abarcando la estrategia, el negocio y la tecnología. Además, al utilizar el enfoque de procesos, se debe considerar la importancia de los costos y beneficios asociados, según una investigación, se concluye que en Chile se hace poca gestión de procesos. En una escala de 1 a 5 se está en 1.15 y se requiere subir un nivel de madurez y llegar a 2.15. El costo de la existencia de esta brecha es de US$ 86 mil millones, prorrateado en 41.996 organizaciones. También se señala que solucionarlo costaría unos US$ 5 mil millones, prorrateado entre las organizaciones consideradas. Por lo tanto, el aporte de gestión de procesos en Chile es US$ 81 mil millones sólo para un tramo, cifra cercana a un tercio del PIB. Por lo anterior, el objetivo de la tesis es desarrollar un plan de negocio para crear una empresa que ofrezca BPM a PYMES y Grandes empresas, que representan el 18% de total en el país y que en total aportan el 97% de las ventas totales en Chile. La metodología utilizada, basada en un plan funcional, permite concentrarse y desarrollar los aspectos estratégicos del negocio, el enfoque comercial, enfoque operativo, enfoque de recursos humanos y el enfoque financiero, para en su conjunto entregar todos los elementos necesarios para abordar el negocio. Se propone desarrollar un plan que implique proveer dos líneas de servicios, 1) BPM en la nube y 2) consultoría tradicional de proyectos BPM, por medio de un equipo especialista en dichos proyectos De los resultados de la evaluación del proyecto considerando los flujos proyectados a 5 años en el escenario base se obtiene un VAN = $58.098.426, con una tasa de descuento del 10% anual, y una TIR=69,61%, por lo cual se concluye que es factible desarrollar un negocio que permita proveer BPM en la nube. Además del análisis de sensibilidad, se puede apreciar que los cambios en la variable 1) asociada a la estimación de los ingresos bases por proyecto, y la variable 2) asociada a la estimación del número de proyectos a realizar por año, no sufrió impactos que llevaran al VAN ser menor a cero. Por lo cual afianza la conclusión anterior, de ser un proyecto económica mente factible. Como recomendación final, se debe evaluar la posibilidad ampliar la capacidad de ejecución de proyectos si la demanda es superior a la considerada en el plan, dado el aumento significativo de proyectos BPM que está experimentando el país.
Libros sobre el tema "BPGM"
1
Gruber, Gerd y Manfred Pallinger. Kommentar zum BPGG. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4.
Texto completo
3
Gerd, Gruber. Kommentar zum BPGG: Bundespflegegeldgesetz. Wien: Springer, 1994.
Buscar texto completo
4
Portmann, Wolfgang, Felix Uhlmann y David U. Gerber. Bundespersonalgesetz (BPG): Bundespersonalgesetz vom 24. März 2000 (BPG). Bern: Stämpfli, 2013.
Buscar texto completo
5
2008 bpm & workflow handbook - spotlight on human-centric bpm. [Place of publication not identified]: Future Strategies, Inc., 2008.
Buscar texto completo
6
Komus, Ayelt, ed. BPM Best Practice. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16725-6.
Texto completo
7
Fleischmann, Albert, Stefan Raß y Robert Singer. S-BPM Illustrated. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36904-9.
Texto completo
8
Stary, Christian, ed. S-BPM ONE – Scientific Research. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29133-3.
Texto completo
9
Fischer, Herbert y Josef Schneeberger, eds. S-BPM ONE - Running Processes. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36754-0.
Texto completo
10
Fleischmann, Albert, Werner Schmidt y Christian Stary, eds. S-BPM in the Wild. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17542-3.
Texto completoCapítulos de libros sobre el tema "BPGM"
1
Gruber, Gerd y Manfred Pallinger. "Einführung". En Kommentar zum BPGG, 1–9. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_1.
Texto completo
2
Gruber, Gerd y Manfred Pallinger. "Abschnitt". En Kommentar zum BPGG, 117–24. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_10.
Texto completo
3
Gruber, Gerd y Manfred Pallinger. "Abschnitt Allgemeine Bestimmungen". En Kommentar zum BPGG, 14–20. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_2.
Texto completo
4
Gruber, Gerd y Manfred Pallinger. "Anspruchsberechtigte Personen". En Kommentar zum BPGG, 21–52. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_3.
Texto completo
5
Gruber, Gred y Manfred Pallinger. "Pflegegeld". En Kommentar zum BPGG, 53–92. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_4.
Texto completo
6
Gruber, Gerd y Manfred Pallinger. "Abschnitt". En Kommentar zum BPGG, 93–95. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_5.
Texto completo
7
Gruber, Gerd y Manfred Pallinger. "Abschnitt". En Kommentar zum BPGG, 96–97. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_6.
Texto completo
8
Gruber, Gerd y Manfred Pallinger. "Verfahren". En Kommentar zum BPGG, 98–114. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_7.
Texto completo
9
Gruber, Gerd y Manfred Pallinger. "Abschnitt". En Kommentar zum BPGG, 115. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_8.
Texto completo
10
Gruber, Gerd y Manfred Pallinger. "Abschnitt". En Kommentar zum BPGG, 116. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-6631-4_9.
Texto completoActas de conferencias sobre el tema "BPGM"
1
Kim, Eun Cheol y Jin Young Kim. "Double binary turbo coding for BPPM-TH and BPAM-DS UWB systems". En 2009 11th IEEE International Conference on High Performance Computing and Communications. IEEE, 2009. http://dx.doi.org/10.1109/hpcc.2009.23.
Texto completo
2
Al Parvez, A., M. A. Khan, M. E. Hoque, Xizhi An y Kyung Sup Kwak. "Performance Evaluation of TH-BPPM and TH-BPAM with Private MAC in UWB Ad-hoc Networks". En The 9th International Conference on Advanced Communication Technology. IEEE, 2007. http://dx.doi.org/10.1109/icact.2007.358483.
Texto completo
3
Fleischmann, Albert, Werner Schmidt y Christian Stary. "Subject-Oriented BPM = Socially Executable BPM". En 2013 IEEE 15th Conference on Business Informatics (CBI). IEEE, 2013. http://dx.doi.org/10.1109/cbi.2013.64.
Texto completo
4
Sprague, Steven. "Modernize the network: Device identity networks meet enterprise needs". En 2013 DSCI - Best Practices Meet (BPM). IEEE, 2013. http://dx.doi.org/10.1109/bpm.2013.6615010.
Texto completo
5
More, Asit y Shashikala Tapaswi. "Dynamic malware detection and recording using virtual machine introspection". En 2013 DSCI - Best Practices Meet (BPM). IEEE, 2013. http://dx.doi.org/10.1109/bpm.2013.6615011.
Texto completo
6
Putchala, Santosh Krishna, Krishna Bhat y R. Anitha. "Information security challenges in social media interactions: strategies to normalize practices across physical and virtual worlds". En 2013 DSCI - Best Practices Meet (BPM). IEEE, 2013. http://dx.doi.org/10.1109/bpm.2013.6615012.
Texto completo
7
Lee, Jihyun, Sungwon Kang, Danhyung Lee, Yu-Whoan Ahn y Andrew Boknam Park. "Comparison of vPMM and BPMM". En 2009 10th ACIS International Conference on Software Engineering, Artificial Intelligences, Networking and Parallel/Distributed Computing. IEEE, 2009. http://dx.doi.org/10.1109/snpd.2009.93.
Texto completo
8
Loja, Luiz Fernando Batista, Sofia L. Costa Paiva y Juliano Lopes Oliveira. "Towards BPM@Runtime". En Workshop em Modelagem e Simulação de Sistemas Intensivos em Software. Sociedade Brasileira de Computação - SBC, 2020. http://dx.doi.org/10.5753/mssis.2020.12491.
Texto completoResumen
Producing software to manage Business Processes (BP) in Information Systems (IS) requires considerable effort and time. This paper describes a software component that uses a Model-Driven Engineering (MDE) approach to support BP management in IS into the context of an IS application framework. The BP Manager component allows the definition of BP models using a high-level language, that is integrated with others framework components to generate the IS applications. This component has important improvements compared to other BP management tools, such as support for collaborative modeling and support for the execution of empirical and ad hoc processes. Furthermore, the integration of the BP management component into the framework brings significant increases in productivity of IS software development and maintenance.
9
Ayoub, Ahmad B. y Mohamed A. Swillam. "Leap-frog-based BPM (LF-BPM) method for solving nanophotonic structures". En Physics and Simulation of Optoelectronic Devices XXVI, editado por Marek Osiński, Yasuhiko Arakawa y Bernd Witzigmann. SPIE, 2018. http://dx.doi.org/10.1117/12.2289201.
Texto completo
10
Batista, Matheus, Andréa Magdaleno y Marcos Kalinowski. "A Survey on the use of Social BPM in Practice in Brazilian Organizations". En XIII Simpósio Brasileiro de Sistemas de Informação. Sociedade Brasileira de Computação, 2017. http://dx.doi.org/10.5753/sbsi.2017.6073.
Texto completoResumen
Social BPM is the combination of Business Process Management (BPM) with social and collaborative techniques for the purpose of exploring collaboration among stakeholders throughout the BPM lifecycle. Its goals are to reduce common problems in BPM by ensuring collaboration and transparency. To the best of our knowledge, there is no information on how Social BPM is being used in organizational environments and on its impacts. This study aims at showing how Brazilian organizations are using Social BPM practices and technologies. Therefore, a survey was conducted with employees from different companies in order to collect data on their usage of BPM collaborative practices. The survey received 31 replies and 3 of the respondents were also interviewed in order to provide depth to their answers and to enhance the overall understanding. The results show that collaboration happens predominantly in design, modeling, and improvement phases. Collaboration still happens mainly without formal planning and without tool support.
Informes sobre el tema "BPGM"
1
Watkins, Heath A. BPPM Position Coefficients. Office of Scientific and Technical Information (OSTI), junio de 2012. http://dx.doi.org/10.2172/1044096.
Texto completo
2
McCrady, Rodney C. BPPM Data acquisition modes. Office of Scientific and Technical Information (OSTI), enero de 2011. http://dx.doi.org/10.2172/1008005.
Texto completo
3
Pinayev, Igor. BPM Button Testing. Office of Scientific and Technical Information (OSTI), julio de 2018. http://dx.doi.org/10.2172/1480939.
Texto completo
4
Church, M. BPM System Improvements. Office of Scientific and Technical Information (OSTI), abril de 1991. http://dx.doi.org/10.2172/983980.
Texto completo
5
Zhang S. Y. SNS Ring BPM. Office of Scientific and Technical Information (OSTI), diciembre de 1999. http://dx.doi.org/10.2172/1157247.
Texto completo
6
Menga P., L. Ahrens y R. Schroeder. AGS BPM Tests. Office of Scientific and Technical Information (OSTI), agosto de 2007. http://dx.doi.org/10.2172/1061879.
Texto completo
7
McGinnis, Dave y /Fermilab. BPM Signal Level Calculation. Office of Scientific and Technical Information (OSTI), febrero de 2001. http://dx.doi.org/10.2172/984580.
Texto completo
8
Talman, R. y N. Malitsky. Beam-Based BPM Alignment. Office of Scientific and Technical Information (OSTI), septiembre de 2002. http://dx.doi.org/10.2172/1157294.
Texto completo
9
Heifets, S., Novokhatski y A. Aleksandrov. A simple low-frequency BPM. Office of Scientific and Technical Information (OSTI), marzo de 2008. http://dx.doi.org/10.2172/926189.
Texto completo
10
Emma, P. y T. Lohse. Difference orbits and BPM-resolutions. Office of Scientific and Technical Information (OSTI), junio de 1988. http://dx.doi.org/10.2172/6907825.
Texto completo