Literatura académica sobre el tema "Dermatite digitée"
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Artículos de revistas sobre el tema "Dermatite digitée":
1
Rodrigues, Celso A., Maria C. R. Luvizotto, Ana Liz G. Alves, Piero H. M. Teodoro y Elisa A. Gregório. "Digital dermatitis of the accessory digits of dairy cows". Pesquisa Veterinária Brasileira 30, n.º 3 (marzo de 2010): 246–48. http://dx.doi.org/10.1590/s0100-736x2010000300010.
Resumen
This report characterizes the digital dermatitis (DD) lesions in the accessory digits of dairy cows and presents data on the applied therapy. Fifteen Holstein cattle with DD affecting the accessory digits of the hindlimbs from four dairy farms with previous history of DD were evaluated. Lesions were excised, the wounds were sutured, and a topical application of oxytetracycline powder covered by bandaging was associated with a single parenteral administration of long acting oxytetracycline IM (20mg/kg). Tissue samples were obtained for histopathology and transmission electronic microscopy (TEM). Lesions from all the animals were recuperated 15 days after surgical procedure. Overal, most DD lesions were papillomatous epidermal projections or wartlike verrucous lesions. Histopathologically, samples revealed hyperplasia of epidermis with hyperkeratosis, several mitoses in the stratum basale and elongated rete ridges in the superficial and middle dermis. TEM revealed long, thin spirochete-like bacteria. Morphologic features of lesions and its response to therapy were comparable to those described for DD.
2
Blowey, R., M. Sharp y S. Done. "Digital dermatitis". Veterinary Record 131, n.º 2 (11 de julio de 1992): 39. http://dx.doi.org/10.1136/vr.131.2.39-a.
3
Vermeersch, A. y G. Opsomer. "Digital dermatitis in cattle". Vlaams Diergeneeskundig Tijdschrift 88, n.º 5 (31 de octubre de 2019): 259–68. http://dx.doi.org/10.21825/vdt.v88i5.15997.
Resumen
Digital dermatitis is the most common cause of lameness worldwide in dairy cattle. In this final part of a twin paper, treatment options and strategies to prevent digital dermatitis are reviewed. There is a wide range of different treatments available but none of them can completely cure the animal. Footbaths and applying high standards for hygiene are ways to keep this disease under control. Moreover, the link to other (human and non-human) treponemal diseases will be discussed. In humans, treponemes are involved in periodontal disease, syphilis and many other illnesses. The dermatological manifestation of some of these human diseases such as yaws have a similar appearance like acute digital dermatitis. Digital dermatitis-like lesions have been described in goats, sheep and elks. The typically isolated Treponema spp. can also be found in equine proliferative pododermatitis affected feet. Besides in digital dermatitis, these bacteria can be found in bovine ulcerative mammary dermatitis and badly healing lesions in cattle.
4
Rashmir-Raven, Ann M., Sharon S. Black, Lora G. Rickard y Mark Akin. "Papillomatous Pastern Dermatitis with Spirochetes and Pelodera Strongyloides in a Tennessee Walking Horse". Journal of Veterinary Diagnostic Investigation 12, n.º 3 (mayo de 2000): 287–91. http://dx.doi.org/10.1177/104063870001200320.
Resumen
Papillomatous digital dermatitis is a common disease in cattle. The pastern dermatitis observed in a horse shared many of the gross characteristics of papillomatous digital dermatitis in cattle. Lesions included a mixture of proliferative and erosive changes, with a verrucose appearance in some areas. Microscopic similarities included pseudoepitheliomatous and papillomatous epidermal hyperplasia with hyperkeratosis, spongiosis of the epidermis, and intraepidermal spirochetes. The horse was also concurrently infected with Pelodera strongyloides. Papillomatous digital dermatitis in cattle is associated with poor husbandry practices. The environment of the affected horse was heavily contaminated with urine, manure, and other organic debris. Verrucous pododermatitis of horses may be the same as or similar to bovine papillomatous digital dermatitis, and these conditions have similar etiologies.
5
Vermeersch, A. y G. Opsomer. "Digital dermatitis in cattle". Vlaams Diergeneeskundig Tijdschrift 88, n.º 5 (31 de octubre de 2019): 247–58. http://dx.doi.org/10.21825/vdt.v88i5.15996.
Resumen
Digital dermatitis or Mortellaro’s disease is a highly prevalent bovine dermatological disorder situated in the foot region that causes lameness and impairs animal welfare. In this first part of a twin paper, the role of genetics, immunity, bacteria and hygiene in the development of this complex disease are described. There is still no consensus regarding the role of the immune system and the typically isolated Treponema spp. in the pathogenesis of digital dermatitis. Moisture and dirt are undoubtedly important for disease transmission in and between dairy farms; furthermore, the genetic component of the disease will be more deeply discussed.
6
Logue, D. "Understanding bovine digital dermatitis". Veterinary Record 168, n.º 8 (25 de febrero de 2011): 212–13. http://dx.doi.org/10.1136/vr.d1284.
7
Lewis, C. "Contagious ovine digital dermatitis". Veterinary Record 169, n.º 24 (9 de diciembre de 2011): 642. http://dx.doi.org/10.1136/vr.d7967.
8
Blowey, Roger. "Clinical Forum: Digital dermatitis". Livestock 11, n.º 4 (julio de 2006): 20–27. http://dx.doi.org/10.1111/j.2044-3870.2006.tb00033.x.
9
Wilson-Welder, Jennifer H., Jarlath E. Nally, David P. Alt, Mitchell V. Palmer, John Coatney y Paul Plummer. "Experimental Transmission of Bovine Digital Dermatitis to Sheep: Development of an Infection Model". Veterinary Pathology 55, n.º 2 (16 de noviembre de 2017): 245–57. http://dx.doi.org/10.1177/0300985817736572.
Resumen
Digital dermatitis is an infectious cause of lameness primarily affecting cattle but also described in sheep, goats, and wild elk. Digital dermatitis is a polymicrobial infection, involving several Treponema species and other anaerobic bacteria. Although the exact etiology has not been demonstrated, a number of bacterial, host, and environmental factors are thought to contribute to disease development. To study host–bacterial interactions, a reproducible laboratory model of infection is required. The objective of this study was to demonstrate key aspects of bovine digital dermatitis lesions in an easy-to-handle sheep model. Crossbred sheep were obtained from a flock free of hoof disease. Skin between the heel bulb and dewclaw was abraded before wrapping to emulate a moist, anaerobic environment. After 3 days, abraded areas were inoculated with macerated lesion material from active bovine digital dermatitis and remained wrapped. By 2 weeks postinoculation, experimentally inoculated feet developed erosive, erythematous lesions. At 4 weeks postinoculation, microscopic changes in the dermis and epidermis were consistent with those described for bovine digital dermatitis, including erosion, ulceration, hyperkeratosis, ballooning degeneration of keratinocytes, and the presence of neutrophilic infiltrates. Silver staining of lesion biopsy sections confirmed that spirochetes had penetrated the host epidermis. The model was then perpetuated by passaging lesion material from experimentally infected sheep into naïve sheep. This model of bovine digital dermatitis will allow for future novel insights into pathogenic mechanisms of infection, as well as the development of improved diagnostic methods and therapeutics for all affected ruminants.
10
Moreira, Tiago Facury, Elias Jorge Facury Filho, Leandro Silva Andrade, Luiz Fernando Cardoso Labre, Karolliny Merlo Goehringer, Otavio Luiz Fidelis Junior, Letícia Marques Rodrigues, Odael Spadeto Jùnior, Guilherme Vieira Fonseca y Antônio Ultimo Carvalho. "Dermatite digital bovina: etiologia e rotas de transmissão". Revista Acadêmica Ciência Animal 16 (14 de diciembre de 2018): 1. http://dx.doi.org/10.7213/1981-4178.2018.163101.
Resumen
A dermatite digital (DD) é uma das principais doenças do sistema locomotor de bovinos que levam os animais à claudicação e causam graves prejuízos econômicos. Desde o seu primeiro relato na Itália, em 1974, a DD atingiu uma situação endêmica em diversos países, incluindo o Brasil. Bactérias do gênero Treponema são os principais agentes envolvidos, pois se apresentam como as bactérias mais abundantes e também estão presentes nas partes mais profundas das lesões. Mais de 20 espécies diferentes de Treponema foram identificados em amostras de DD, sendo as espécies T. pedis, T. medium, T. phagedenis, T. refringens e T. denticula as mais relatadas. Uma diversidade de outras bactérias como Mycoplasma, Fusobacterium, Porphyromonas, Bacteroides spp., Campylobacter spp., Guggenheimella spp. e D. nodosus também foram descritas. Tentativas de induzir a doença artificialmente só foram bem sucedidas com o uso de macerado de lesões ativas, demonstrando a importância do sinergismo bacteriano. Apesar da quantidade de estudos sobre o tema, a determinação da etiologia definitiva da DD permanece sendo um desafio, principalmente em relação ao papel que as diferentes bactérias encontradas desempenham no desenvolvimento da lesão. A epidemiologia desta doença também apresenta aspectos pouco esclarecidos, como os possíveis reservatórios e como ocorre a sua transmissão. Os filotipos de Treponema envolvidos na DD foram detectados na cavidade oral, rúmen, fezes e no ambiente de fazendas que possuíam a doença, porém sempre em pequenas quantidades, o que mantém em questão a importância destes locais como reservatórios.
Tesis sobre el tema "Dermatite digitée":
1
Relun, Anne. "Evaluation des mesures de maîtrise de la dermatite digitée dans les troupeaux bovins laitiers". Nantes, Ecole nationale vétérinaire, 2011. https://doc-veto.oniris-nantes.fr/GED_CHN/193068091124/These_AnneRELUN.pdf.
Resumen
L’objectif de cette thèse était d’évaluer des mesures jugées prometteuses pour diminuer durablement la prévalence de la dermatite digitée (DD) dans les troupeaux bovins laitiers. Les pratiques de traitement devaient être efficaces, acceptables pour les éleveurs et non toxiques pour l’Homme et l’Environnement. Une première partie s’est intéressée aux freins et motivations des éleveurs français vis-à-vis des pratiques de traitement de la DD. Il en ressortait le besoin d’identifier des régimes optimaux d’application des traitements, tout en étudiant des alternatives au pédiluve pour l’application de traitements collectifs. Après avoir mis au point et évalué une méthode simple de notation de la DD en salle de traite, un essai clinique a été mené dans 52 troupeaux bovins laitiers. Cet essai a permis d’évaluer, à l’aide d’analyses de survie, l’efficacité relative de 4 protocoles de traitement et des pratiques d’élevage pour diminuer l’incidence et améliorer la guérison des lésions de DD. Il a été montré qu’un traitement à base de minéraux chélatés appliqué 2 jours toutes les 2 semaines, via un pédiluve de passage ou une application par spray en salle de traite est efficace pour diminuer l’incidence et améliorer la guérison clinique des lésions de DD. La propreté des pieds et la réalisation d’un parage avant la détection d’une lésion de DD jouaient également un rôle essentiel. Enfin, l’impact de la DD sur la production laitière a pu être estimé à 0,6 à 0,9 kg/jour. Les résultats de cette thèse renforcent la nécessité d’une approche globale qui intègre des protocoles de traitement et les pratiques d’élevage pour élaborer des stratégies de contrôle de la DD efficaces et rentables.
2
Bonacin, Yuri da Silva. "Expressão e quantificação de receptores vanilóides TRPV1 na dermatite digital bovina /". Jaboticabal, 2017. http://hdl.handle.net/11449/150352.
Resumen
Orientador: José Antonio MarquesCoorientador: Sérgio Britto Garcia
Banca: Deborah Penteado Martins Dias
Banca: Paulo Aléscio Canola
Resumo: A Dermatite Digital Bovina (DDB) constitui uma das principais causas de graus elevados de claudicação em bovinos leiteiros, em função da dor que estes animais aparentam frente ao estímulo nocioceptivo. A hiperalgesia em alguns casos de dor crônica está relacionada à expressão exacerbada de fibras dos receptores vaniloides TRPV1, podendo haver forte correlação com casos crônicos da DDB. No presente estudo foram utilizados 15 bovinos, fêmeas, da raça Holandesa Preto e Branco, com idades de 2 a 7 anos, em lactação com pico médio de 47,85 L, mantidos em regime "free-stall". Durante o casqueamento realizado na propriedade, as lesões da DDB foram identificadas e divididas em quatro grupos, referentes aos quatro estágios da doença (inicial M1, clássico M2, intermediário M3 e crônico M4). Foram coletadas biópsias por meio de "punch" cutâneo (4mm). Além das lesões foram coletadas amostras de pele sadia de cada animal. Priori às biopsias realizou-se a dimensionamento das lesões, para média comparativa entre os estágios. Os fatores predisponentes ao aparecimento de lesões (idade, número de partos e pico de lactação) foram considerados. As biopsias foram processadas em laboratório e colocadas frente à reação imunológica com anticorpos anti-TRPV1 (Chemicon -USA). Posteriormente as fibras imuno-marcadas nos quatro grupos e pele sadia foram contabilizadas e comparadas. As dimensões das lesões foram analisadas pelo método estatístico descritivo e possuíam média de comprimento e largura no es... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The Bovine Digital Dermatitis (BDD) is one of the main cause on high claudication levels at the dairy cattle, as a result of the pain that appear in those animal front of the nociceptive stimulus. Hyperalgesia in some chronic pain cases is related to the exacerbated expression of vanyloid TRPV1 fibers, and may have a hole on the chronic cases of BDD. In the present study, 15 Black and White Holstein cow was used, aged 2 to 7 years old, during lactation with mean peak of 47.85L, kept in the free-stall under the same diet. BDD lesions were identified and divided into 4 stages of the disease (initial M1, classic M2, intermediate M3 and chronic4), which skin are collected by dermal punch (4mm). In addition to the lesions, healthy skin samples were collected from each animal. Prior to the biopsies, the lesion dimensions were taken, for comparative average between the stages. Predisposing factors to the lesions appearance (age, number of births and lactation peak) were considered. The biopsies were processed at the laboratory and reacted with anti-TRPV1 antibodies (Chemicon -USA). The immuno-marked fibers in the four groups and healthy skin were counted and compared. The lesion dimensions were analyzed by descriptive statistical method and had a M1 mean length/ width on M1 of 5,60mm±3,20 x 4,4±1,34mm, M2 of 12,60±6,46mm x 14,4±8,87mm, M3 of 21,60±3,36mm x 17,20±6,61mm and M4 of 21,60±3,36mm x 24,57±7,32mm. The thickness mean value in M1 of 1.80 ± 1.09mm, M2 of 6.20 ± 2.16mm, M3 of 7.40 ± 6.54mm and M4 of 8.85 ± 4.14mm. The predisposing factors results were analyzed separately with the number of lesions by Pearson Correlation statistic method (p <0.05). There was difference between more lesion and birth numbers. TPV1 fiber counts were analyzed by logarithmic scale (p <0.05), with a significant difference between the M4 group (chronic stage of DDB) and the other groups.
Mestre
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Loureiro, Marcos Gomes. "Concentrações de oxitetraciclina de longa ação vias sistêmica ou tópicas no leite, líquido sinovial e plasma de vacas acometidas de dermatite digital papilomatosa /". Botucatu, 2007. http://hdl.handle.net/11449/88913.
Resumen
Orientador: Celso Antonio RodriguesBanca: José Luiz de Mello Nicoletti
Banca: José Wanderley Cattelan
Resumo: A Dermatite Digital Papilomatosa (DDP) é uma enfermidade com etiologia bacteriana associadas às espiroquetas. O tratamento consiste na administração de antimicrobianos parenterais ou tópicos, destacando-se especialmente as tetraciclinas. Os objetivos deste trabalho foram analisar e comparar a eficiência do tratamento tópico e sistêmico com oxitetraciclina em vacas acometidas por DDP, e a presença de resíduos deste antimicrobiano no leite e suas concentrações no líquido sinovial e plasma. Foram utilizadas 8 vacas no grupo 1 tratadas topicamente e 8 no grupo 2 tratadas por via sistêmica . As amostras foram coletadas nos momentos M0: anterior aos tratamentos, M1: 6 horas pós-tratamento, M2: 12 horas após, e em intervalos de 12 horas até o M23. A eficiência dos tratamentos foi avaliada através do grau de claudicação e da extensão da lesão. As concentrações do antimicrobiano de oxitetraciclina foram determinadas por HPLC. As vacas do Grupo 1 apresentaram redução das lesões e no grau de claudicação e as do grupo 2 não demonstraram melhora nas lesões e elevação no grau de claudicação. As concentrações avaliadas em leite, líquido sinovial e plasma no Grupo 1, revelaram valores abaixo dos limites de detecção estabelecidos pelo HPLC. A avaliação dos resíduos de oxitetraciclina no leite do Grupo 2, entre M1 e M23, encontram-se acima dos limites máximos estabelecidos pela legislação. Conclui-se que a oxitetraciclina em pó foi eficiente para o tratamento de DDP e não apresenta resíduos em plasma, líquido sinovial e leite e que o tratamento sistêmico apresenta baixa eficiência e elevadas concentrações no leite
Abstract: Papillomatous digital dermatitis (PDD) is a restricted digital disease caused by a spirochete-like and other bacterias. The treatment consists of administrating systemic or topics antibiotics, especially tetracyclines. With this work it is intended to compare the efficiency of the topical and systemic treatment with oxitetracycline in cows with PDD and analyze the presence of residues of this antibiotic in the milk and its concentration in the sinovial liquid and plasma. The total of 16 lactating cows with PDD were divided in 2 treatment groups. The samples were obtained in the moments M0: previous to the treatments, M1: 6 hours pos treatment, M2: 12 hours after treatment, and in intervals of 12 hours after treatment until M23. The efficiency of the treatment was evaluated through the lameness degree and the extension of the lesion. The assayed for oxitetracycline content was measured by means of HPLC. The cows of the Group 1 presented reduction of the lesions and in the lameness degree. Cattle of the Group 2 did not demonstrate improvement in the lesions and showed elevation in the lameness degree. The concentration of sinovial fluid and plasma in the milk of cows belonging to Group 1 revealed values below the established detection limits for HPLC in milk. The evaluation of the residues of oxitetracycline in the milk of the Group 2, between M1 and M23, were above the maximum limits established by legislation. As a matter of conclusion it is argued that the powdered oxitetracycline was efficient for the treatment of PDD and it does not present residues in milk, level of plasma or sinovial fluid. Otherwise, the systemic treatment presents low efficiency and high concentration of such substance in the milk
Mestre
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Nascimento, Cristiane Lassálvia [UNESP]. "Estudo comparativo do efeito da terapia fotodinâmica e uso de antibióticos em lesões podais (Bumblefoot) em pinguins de Magalhães (Spheniscus magellanicus)". Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/124100.
Resumen
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000831292.pdf: 3855958 bytes, checksum: f0eddfd2bd8c33b972b6c00be59dda5a (MD5)O objetivo do estudo foi testar um protocolo de tratamento para pododermatite classe III em um grupo de Spheniscus magellanicus mantidos em cativeiro utilizando terapia fotodinâmica (TFD) e compará-lo com outro tratado com antibióticos (ATB). Todos os animais foram submetidos inicialmente à debridamento cirúrgico da área da lesão e em seguida aleatoriamente separados em um grupo TFD e outro ATB, contendo 11 lesões cada. No grupo ATB utilizou-se pomada antibiótica três vezes por semana e antibiótico e anti-inflamatório sistêmicos diariamente. No grupo TFD, terapia fotodinâmica foi aplicada três vezes por semana sem a utilização de medicação sistêmica. Fotografias da área da lesão, swab para cultura e antibiograma e sangue para hemograma e bioquímica sanguínea foram coletados no início e a cada 14 dias perfazendo um total de 84 dias. Os resultados reafirmaram a natureza recidivante dessas lesões que se iniciam a partir do ponto de apoio. A prevalência das bactérias ao longo do tempo não foi uniforme, sendo a realização de antibiogramas para escolha de uma droga apropriada necessário em diferentes momentos. Na comparação, o grupo TFD apresentou desempenho melhor com 63,62% de cura em um tempo médio de 42 dias, contra 9,09% de cura em um tempo médio de 70 dias no grupo ATB. Os achados do presente estudo atestam a eficácia da Terapia Fotodinâmica para o tratamento de pododermatite classe III para Spheniscus magellanicus
The aim of the study was to test a treatment protocol for pododermatitis class III in a group of captive Spheniscus magellanicus using photodynamic therapy (PDT) and compare it with another treated with antibiotics (ATB). All animals initially underwent surgical debridement of the lesion area and then they were randomly divided into one TFD and one ATB group, each containing 11 injuries. In the ATB group antibiotic ointment was used three times a week and systemic antibiotic and anti-inflammatory daily. In PDT group, photodynamic therapy has been applied three times a week without the use of systemic medication. Photos of the lesion area, swab for culture and sensitivity and blood for blood count and blood chemistry were collected on the first day and every 14 days for a total of 84 days. The results reaffirmed the relapsing nature of these lesions that begin from the point of support. The prevalence of bacteria over time was not uniform and there was need to carry out antibiograms at different times to select an appropriate drug. In comparison, the PDT group showed the best performance with 63.62% on an average healing time of 42 days, compared to 9.09% in an average healing time of 70 days in the ATB group. The findings of this study attest to the effectiveness of photodynamic therapy for the treatment of class III to pododermatitis Spheniscus magellanicus
5
Nascimento, Cristiane Lassálvia. "Estudo comparativo do efeito da terapia fotodinâmica e uso de antibióticos em lesões podais (Bumblefoot) em pinguins de Magalhães (Spheniscus magellanicus) /". Botucatu, 2014. http://hdl.handle.net/11449/124100.
Resumen
Orientador: Carlos Roberto TeixeiraBanca: Sheila Canevese Rahal
Banca: Alyne Simões Gonçalves
Resumo: O objetivo do estudo foi testar um protocolo de tratamento para pododermatite classe III em um grupo de Spheniscus magellanicus mantidos em cativeiro utilizando terapia fotodinâmica (TFD) e compará-lo com outro tratado com antibióticos (ATB). Todos os animais foram submetidos inicialmente à debridamento cirúrgico da área da lesão e em seguida aleatoriamente separados em um grupo TFD e outro ATB, contendo 11 lesões cada. No grupo ATB utilizou-se pomada antibiótica três vezes por semana e antibiótico e anti-inflamatório sistêmicos diariamente. No grupo TFD, terapia fotodinâmica foi aplicada três vezes por semana sem a utilização de medicação sistêmica. Fotografias da área da lesão, swab para cultura e antibiograma e sangue para hemograma e bioquímica sanguínea foram coletados no início e a cada 14 dias perfazendo um total de 84 dias. Os resultados reafirmaram a natureza recidivante dessas lesões que se iniciam a partir do ponto de apoio. A prevalência das bactérias ao longo do tempo não foi uniforme, sendo a realização de antibiogramas para escolha de uma droga apropriada necessário em diferentes momentos. Na comparação, o grupo TFD apresentou desempenho melhor com 63,62% de cura em um tempo médio de 42 dias, contra 9,09% de cura em um tempo médio de 70 dias no grupo ATB. Os achados do presente estudo atestam a eficácia da Terapia Fotodinâmica para o tratamento de pododermatite classe III para Spheniscus magellanicus
Abstract: The aim of the study was to test a treatment protocol for pododermatitis class III in a group of captive Spheniscus magellanicus using photodynamic therapy (PDT) and compare it with another treated with antibiotics (ATB). All animals initially underwent surgical debridement of the lesion area and then they were randomly divided into one TFD and one ATB group, each containing 11 injuries. In the ATB group antibiotic ointment was used three times a week and systemic antibiotic and anti-inflammatory daily. In PDT group, photodynamic therapy has been applied three times a week without the use of systemic medication. Photos of the lesion area, swab for culture and sensitivity and blood for blood count and blood chemistry were collected on the first day and every 14 days for a total of 84 days. The results reaffirmed the relapsing nature of these lesions that begin from the point of support. The prevalence of bacteria over time was not uniform and there was need to carry out antibiograms at different times to select an appropriate drug. In comparison, the PDT group showed the best performance with 63.62% on an average healing time of 42 days, compared to 9.09% in an average healing time of 70 days in the ATB group. The findings of this study attest to the effectiveness of photodynamic therapy for the treatment of class III to pododermatitis Spheniscus magellanicus
Mestre
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Demirkan, Ibrahim. "Spirochaetes in bovine digital dermatitis". Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367083.
7
Staton, Gareth. "Bovine digital dermatitis : a reverse vaccinology approach". Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3021310/.
8
Sanfelice, Cristiane 1985. "Pododermatite e qualidade de carcaça de frangos de corte suplementados com minerais orgânicos e vitamina E /". Botucatu, 2015. http://hdl.handle.net/11449/132920.
Resumen
Orientador: Ariel Antonio MendesBanca: Marcia Regina Fernandes Boaro Martins
Banca: Ibiara Correia de Lima Almeida Paz
Banca: Rodrigo Garofallo Garcia
Banca: José Roberto Sartori
Resumo: Com objetivo de avaliar a influência dos minerais orgânicos (selênio e zinco) e vitamina E sobre a incidência e identificação microbiológica de pododermatite, lesões de carcaça, resistência da pele, desempenho, rendimento de carcaça e partes, qualidade da carne e sistema imune em frangos de corte, dois experimentos foram conduzidos no aviário experimental da FMVZ, UNESP, Câmpus de Botucatu. Para isto, utilizou-se 1260 pintos de um dia de idade, machos, da linhagem Cobb® 500 para cada experimento, alojados com densidade populacional de 12 aves/m², por 42 dias. O programa alimentar foi dividido em quatro fases e o delineamento experimental adotado foi o inteiramente casualisado em esquema fatorial 3x2+1, no experimento 1, três níveis de zinco orgânico (0, 45, 90 mg/kg de ração) dois níveis de selênio orgânico (0 e 0,3 mg/kg de ração) e uma dieta controle, no experimento 2 três níveis de vitamina E (100, 150 e 200UI/kg de ração) e duas fontes microminerais inorgânico (0,3 mg/kg Se + 60 mg/kg de Zn) ou orgânico (0,3 mg/kg de Se e 45 mg/kg de Zn) e uma dieta controle, com 6 repetições de 30 aves cada. Aos 10 dias de idade todas as aves foram vacinadas contra a Doença de Newcastle (experimento 2), os parâmetros imunológicos foram avaliados por meio de colheitas de sangue aos 10, 21 e 42 dias. Aos 41 dias de idade todas as aves foram avaliadas no aviário quanto a incidência de pododermatite. Foi avaliado o desempenho e aos 42 dias de idade as aves foram abatidas no abatedouro experimental da FMVZ, UNESP para avaliação da incidência de lesões de carcaça, resistência da pele, rendimento de carcaça e partes, qualidade de carne, quantificação microbiológica, histologia do coxim plantar e pele. Aves que receberam zinco e selênio orgânico apresentaram maior quantidade de colágeno e a epiderme mais espessa (P≤0,05). Para lesões de carcaça houve diferença...
Abstract: In order to evaluate the influence of organic minerals (selenium and zinc) and vitamin E on the incidence and microbiological identification of foot pad dermatitis, carcass lesions, skin resistance, performance, carcass yield and parts, meat quality and immune system in chickens cutting, two experiments were conducted in the experimental avian FMVZ, UNESP, Botucatu. For this, we used 1,260 chicks at day old male Cobb® the 500 strain for each experiment, housed with a density of 12 birds / m² for 42 days ...
Doutor
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Newbrook, K. L. "Dissecting host-pathogen interactions in bovine digital dermatitis". Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3019337/.
Resumen
Bovine digital dermatitis (BDD) is an inflammatory infectious disease of the digital skin and is of increasing global importance for animal welfare and food security as one of the most important causes of severe lameness in dairy cattle. Whilst three phylogroups of spirochaetes of the genus Treponema (Treponema medium, Treponema phagedenis and Treponema pedis) are highly associated with BDD, having been consistently isolated from lesions, their individual roles in BDD pathogenesis within the bovine foot skin tissue have yet to be elucidated. The poor characterisation of BDD pathogenesis has, to-date, largely hindered development of novel therapeutics and vaccines against BDD. The work presented within this thesis aimed to investigate host-pathogen interactions underlying BDD and determine whether individual Treponema phylogroups implement distinct pathogenic mechanisms upon cells of the bovine foot skin tissue. Primary fibroblast and keratinocyte cells were successfully isolated and subsequently cultured from bovine dermal and epidermal foot skin tissues, respectively, and were then characterised by immunofluorescent staining and RT-PCR, using cell markers, to provide a useful model for studying host-pathogen interactions of BDD. The skin model was subsequently implemented to compare global transcriptional profiles of bovine foot skin fibroblasts following stimulation with representative strains of the three predominant BDD treponeme phylogroups using an RNA-Seq approach. This study is the first to report distinct differences in the dysregulation of global gene expression induced by BDD Treponema phylogroups in bovine fibroblasts. T. medium phylogroup and T. pedis were found to dysregulate host actin rearrangement and appeared to induce loss of cell adhesion via the RND1 gene. Whilst T. medium phylogroup was profoundly less stimulatory, it also appeared to induce immune suppression through unique upregulation of the TSC22D3 gene. T. phagedenis phylogroup uniquely upregulated the antimicrobial peptide precursor, β-defensin 123. Bovine fibroblasts appeared to demonstrate a strong pro-inflammatory response to Gram-negative bacterial lipopolysaccharide through the interleukin-17 signalling pathway; however, BDD treponemes specifically upregulated expression of five inflammatory mediators; most notably interleukin-8. Commensal treponemes are commonly found within the gastrointestinal tract and provide an effective tool for comparison in host-pathogen interaction studies. In absence of a known non-pathogenic treponeme of the bovine skin, a novel spirochaete isolate of the bovine rumen was genotypically and phenotypically characterised, being proposed as novel species, Treponema ruminis, for use as a control organism during RNA-Seq. Despite considerable genotypic and phenotypic differences, global gene expression profiles induced by T. ruminis and T. phagedenis phylogroup and T. pedis spirochaetes were markedly similar. Further to this study, the molecular diversity of a putative outer membrane protein (OMP) was investigated across 121 strains representing three predominant BDD treponeme phylogroups. Gene sequencing of the novel putative OMP revealed limited intra-phylogroup diversity, suggesting that immune selection was not significantly influencing the evolution of this gene and that it may be a useful candidate for future vaccine development. Collectively, these studies increase previously limited knowledge of the pathogenic mechanisms of BDD treponemes and provide novel insights into the host-pathogen interactions between specific treponeme phylogroups and bovine foot skin fibroblast cells during infection. Several genes identified in this study may be useful targets for the development of novel therapeutics and require further investigation.
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Scholey, Rachel Anne. "Investigating host genetic susceptibility to bovine digital dermatitis". Thesis, University of Liverpool, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569442.
Resumen
Bovine digital dermatitis (BDD) is a bacterial infectious disease of bovine hoof skin and is the leading cause of dairy cattle lameness. The disease presents as painful "strawberry-like" lesions that develop on the hind hoof digital skin, in between the heel bulbs. Holstein cattle are very susceptible to BDD and anecdotal evidence suggests BDD is less frequently seen in other breeds of cattle, both dairy and beef. Also, within a herd with BDD, there is great variation in how individual cattle are affected; some are recurrently and severely affected, whereas others are apparently untouched. This between and within breed variation in individual responses strongly suggests an underlying genetic susceptibility or resistance to BDD. This thesis presents the first study of host genetic susceptibility to BDD. Chronically affected BDD cases (n=72) and controls that did not present with BDD lesions (n=97) were identified from Holstein Friesian herds in England and Wales endemic ally affected by BDD during longitudinal farm visits. BDD candidate single nucleotide polymorphisms (SNPs) were identified using two approaches. In the first approach, 16 candidate genes were chosen from the available literature and extensive SNP discovery was conducted for each gene. This was achieved by "in silica" database searching for publicly available SNPs and also by dHPLC (WAVE) screening and sequencing of gene regions. Secondly, a genome-wide association study (GWAS), using the Illumina bovine SNP50beadchip, was performed with a small number of BDD cases (n=23) and controls (n=24). From these two approaches, the most likely associated SNPs were selected for analysis on the full cohort. Sequenom iPLEXTm Gold genotyping was used to genotype 125 candidate gene- identified SNPs and 81 GWAS-identifIed SNPs on the full cohort of cases and controls. The allele frequencies were analysed using Fisher's exact test and Cochran- Mantel- Haenszel 2x2xk test, where herd origin was a stratifying factor. P values were corrected for multiple testing after point-wise 100,000 maxT permutations testing. Eight SNPs were significantly associated (p<0.05) with BDD risk or protection; seven informed from the GWAS and one from the candidate gene study. vii One significant SNP was located in an intron of Anaphase promoting complex subunit 4 (ANAPC4), two were located in introns of HTRA Serine Peptidase 1 (HTRAl) and one was located upstream of SI 00 calcium binding protein A8 (SI OOA8). Six of the eight significant SNPs were located across a gene-rich 3.5Mb region on chromosome 26. This was considered a BDD candidate region requiring further investigation. A haplotype analysis revealed one haplotype block, spanning the HTRAl gene, which was significantly associated with BDD protection. The frequencies of the risk alleles for the eight significant SNPs were compared in eleven BDD unaffected breeds (beef and dairy). Three of the SNPs had lower risk allele frequencies in all breeds tested, and a further three had no more than two breeds where risk allele frequency was higher than in Holstein cases. This might indicate that non Holstein Friesian breeds are at lower BDD risk, at least for some SNPs. However, a lot of questions regarding whether other breeds are exposed to the causative pathogens in the same way as Holstein Friesians remain unanswered. These preliminary BDD-genetic associations need to be validated in independent populations of Holstein Friesian cattle. Susceptibility to infectious disease is governed by a complex interaction of genes and environment, and the sample size in this study was probably too small to detect all underlying BDD genetic variation. However, the significant associations that have been yielded demonstrate that this approach is successful for genetic study of bacterial infectious diseases in cattle, and provides the foundations on which to base further study of BDD host genetic susceptibility.
Libros sobre el tema "Dermatite digitée":
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Papillomatous digital dermatitis on U.S. dairy operations: Footwarts. Fort Collins, Colo: U.S. Dept. of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, 1997.
Capítulos de libros sobre el tema "Dermatite digitée":
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"Digitate dermatitis". En Dermatology Therapy, 189. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/3-540-29668-9_823.
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Santos, Carla Rayane Dos, Ericka Wanessa da Silva Costa, Ilanna Vanessa Pristo de Medeiros Oliveira, Camila Marinho De Miranda Oliveira Meireles, Regina Valéria da Cunha Dias, Fernanda Pereira Da Silva Barbosa y Muriel Magda Lustosa Pimentel. "DERMATITE DIGITAL EM RUMINANTES: REVISÃO". En Atualidades em Medicina Tropical na América do Sul: Veterinária, 165–79. Stricto Sensu Editora, 2021. http://dx.doi.org/10.35170/ss.ed.9786586283594.10.
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Laven, Richard A. y Linda J. Laven. "Infectious Diseases: Bovine Digital Dermatitis". En Reference Module in Food Science. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-818766-1.00065-9.
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Monaghan, Tanya M. y James D. Thomas. "Skin". En Oxford Handbook Clinical Tutor Study Cards: Medicine, 261–302. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198830849.003.0008.
Resumen
This chapter concerns dermatology, and covers describing a skin lesion, benign melanocytic naevus, melanoma, basal cell carcinoma, squamous cell carcinoma, seborrhoeic dermatitis, psoriasis, dermatomyositis, digital clubbing, tuberous sclerosis, hereditary haemorrhagic telangiectasia, xanthomata, vitiligo, pseudoxanthoma elasticum, lichen planus, Raynaud’s phenomenon, Peutz–Jeghers syndrome, Sturge–Weber syndrome, Ehlers–Danlos syndrome, eczema, and urticaria.
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Bell, Nick J. "Optimising foot health in dairy cattle". En Improving dairy herd health Improving, 351–94. Burleigh Dodds Science Publishing, 2021. http://dx.doi.org/10.19103/as.2020.0086.14.
Resumen
This chapter examines optimising foot health in dairy cattle. The chapter begins by reviewing the importance of lameness then goes on to discuss claw horn disruption. It also reviews aetiopathogensis of white line bruising and lesions, which is then followed by a section on aetiopathogensis and control of digital dermatitis. A case study on an 800 cow Holstein herd with a sudden rise in sole ulcers and white line lesions is also included. The chapter concludes with an overview of the emerging diseases in dairy cattle.
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Colussi, Giuliana, Delfina Inda, Yael Zin, Santiago De Matos Lima, Maria Valeria Angles, Silvina Bruey, Ana Lanteri Sambrizzi, Luis Mazzuoccolo, Daniel Luna y Fernando Plazzotta. "Designing an Atopic Dermatitis Community that Integrates Patient Self-Uploaded Information into the EHR to Optimize Follow-up". En MEDINFO 2021: One World, One Health – Global Partnership for Digital Innovation. IOS Press, 2022. http://dx.doi.org/10.3233/shti220135.
Resumen
Atopic dermatitis is a common chronic dermatological disease in childhood that can affect people’s quality of life. The aim of this study was to inquire about the difficulties, needs and interests related to the disease that people with eczema and their caregivers have; in order to develop a tool that is useful for the follow-up of the illness. Electronic surveys were sent to potential users and interviews were conducted with professionals who are specialized on the subject. The main findings allowed us to understand the challenges and situations they face on a daily basis, such as the difficulties related to the family support, the queries on the eczema flare-ups, the struggles with the adherence to treatment and the needs of optimizing their quality of life. These results helped us design a tool that allows patients and their companions to better monitor their disease while optimizing communication with their health professionals.
Informes sobre el tema "Dermatite digitée":
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Krull, Adam C., Jan K. Shearer, Patrick J. Gorden, Vickie L. Cooper, Gregory J. Phillips y Paul J. Plummer. Bacterial Causes of Digital Dermatitis (DD) in Dairy Cattle. Ames (Iowa): Iowa State University, enero de 2015. http://dx.doi.org/10.31274/ans_air-180814-1293.