Literatura académica sobre el tema "Gonadotropin-Releasing hormones"

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Artículos de revistas sobre el tema "Gonadotropin-Releasing hormones"

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Podhorec, P., and J. Kouril. "Induction of final oocyte maturation in Cyprinidae fish by hypothalamic factors: a review." Veterinární Medicína 54, No. 3 (2009): 97–110. http://dx.doi.org/10.17221/50/2009-vetmed.

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Gonadotropin-releasing hormone in Cyprinidae as in other Vertebrates functions as a brain signal which stimulates the secretion of luteinizing hormone from the pituitary gland. Two forms of gonadotropin-releasing hormone have been identified in cyprinids, chicken gonadotropin-releasing hormone II and salmon gonadotropin-releasing hormone. Hypohysiotropic functions are fulfilled mainly by salmon gonadotropin-releasing hormone. The only known factor having an inhibitory effect on LH secretion in the family Cyprinidae is dopamine. Most cyprinids reared under controlled conditions exhibit signs of
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Saleh, Ahmed A., Nada N. A. M. Hassanine, Taha K. Taha, Amr M. A. Rashad, and Mahmoud A. Sharaby. "Molecular regulation and genetic basis of gonadotropin-releasing hormone genes: A review." Applied Veterinary Research 2, no. 4 (2023): 2023017. http://dx.doi.org/10.31893/avr.2023017.

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This review systematically introduces basic information on the hypothalamic pituitary-gonad axis and provides knowledge on the regulation, location, function, reproduction, gene mutations, disorders, sexual behavior, life cycle, and effect of environmental factors on the gonadotropin-releasing hormone gene. On the other hand, this review focused on the GnRH gene, regulations, receptor structures, and their signaling pathways, in addition to its related genes and its effect on crucial hormones such as follicle-stimulating hormone, luteinizing hormone, testosterone, estradiol, and progesterone.
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Crowley, W. R. "Toward Multifactorial Hypothalamic Regulation of Anterior Pituitary Hormone Secretion." Physiology 14, no. 2 (1999): 54–58. http://dx.doi.org/10.1152/physiologyonline.1999.14.2.54.

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The hypothalamus regulates the secretion of anterior pituitary hormones via release of releasing hormones into the hypophysial portal vasculature. Additional neuromessengers act at the pituitary to modulate responses to the hypothalamic hormones. For example, neuropeptide Y enhances the effect of gonadotropin-releasing hormone and the response to the prolactin-inhibiting hormone dopamine.
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King, Judy A., and Robert P. Millar. "Evolution of gonadotropin-releasing hormones." Trends in Endocrinology & Metabolism 3, no. 9 (1992): 339–46. http://dx.doi.org/10.1016/1043-2760(92)90113-f.

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Janjic, M. Marija, Ana Milosevic, and Ivana Bjelobaba. "Gonadotropin-releasing hormone regulated transcription of gonadotropin subunit genes." Biologia Serbica 41, no. 2 (2019): 51–56. https://doi.org/10.5281/zenodo.3532061.

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<strong>Summary.</strong> Two gonadotropins, luteinizing hormone and follicle-stimulating hormone, are synthetized and secreted by anterior pituitary gonadotropes and act on the gonads, controlling gametogenesis and sex hormone production. These hormones are glycoprotein polypeptides, composed of specific beta subunits and a common, alpha subunit. Both transcription and secretion of gonadotropins are regulated by gonadotropin-releasing hormone (GnRH), which is produced by a small number of hypothalamic neurons within the preoptic area and mediobasal hypothalamus. GnRH is released and reaches t
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Pehlivan, Erkan, Hüseyin Polat, and Gürsel Dellal. "Annual Change of Reproductive Hormones in Female Angora Goats." Turkish Journal of Agriculture - Food Science and Technology 5, no. 4 (2017): 343. http://dx.doi.org/10.24925/turjaf.v5i4.343-348.1220.

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In this research, annual changes of melatonin, gonadotropin-releasing hormone, follicle stimulating hormone, luteinizing hormone, estrogen, testosterone and progesterone were studied on 6 heads of 1.5 years old female Angora goat. To determine hormones concentrations, blood samples were taken from jugular vein of each goat in every month for a year. The blood samples were centrifuged at 4000xg for 5 min. and serum was stored at -20°C until analyses time. Hormones analyses in the serum were performed by enzyme immunoassay (EIA) method. Monthly climatic values and photoperiod were obtained from
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SHERWOOD, NANCY M., DAVID A. LOVEJOY, and IMOGEN R. COE. "Origin of Mammalian Gonadotropin-Releasing Hormones." Endocrine Reviews 14, no. 2 (1993): 241–54. http://dx.doi.org/10.1210/edrv-14-2-241.

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Kotlyar, Alexander M., Lubna Pal, and Hugh S. Taylor. "Eliminating Hormones With Orally Active Gonadotropin-releasing Hormone Antagonists." Clinical Obstetrics & Gynecology 64, no. 4 (2021): 837–49. http://dx.doi.org/10.1097/grf.0000000000000664.

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Richalet, Jean-Paul, Murielle Letournel, and Jean-Claude Souberbielle. "Effects of high-altitude hypoxia on the hormonal response to hypothalamic factors." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 299, no. 6 (2010): R1685—R1692. http://dx.doi.org/10.1152/ajpregu.00484.2010.

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Acute and chronic exposure to high altitude induces various physiological changes, including activation or inhibition of various hormonal systems. In response to activation processes, a desensitization of several pathways has been described, especially in the adrenergic system. In the present study, we aimed to assess whether the hypophyseal hormones are also subjected to a hypoxia-induced decrease in their response to hypothalamic factors. Basal levels of hormones and the responses of TSH, thyroid hormones, prolactin, sex hormones, and growth hormone to the injection of TRH, gonadotropin-rele
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Naser, Maryam Mohsin, Thualfiqar Ghalib Turki, and Noor alhuda Ahmed kadhim. "ASSESSMENT OF GONADOTROPIN-RELEASING HORMONE LEVELS IN OBESE WOMEN WITH POLYCYSTIC OVARY SYNDROME." International Journal of Medical Science and Dental Health 11, no. 01 (2025): 01–05. https://doi.org/10.55640/ijmsdh-11-01-01.

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Gonadotropin-releasing hormone (GnRH) is one of the major hormones affecting the reproductive system, and when elevated, it leads to polycystic ovarian syndrome. Obesity is a main cause of GnRH elevation. A current study was conducted from October to December 2024 and included 100 samples from Iraqi women diagnosed with polycystic ovary syndrome (PCOS), collected from the Infertility Center at Al-Sadder Medical City and Al-Zahraa Teaching Hospital, alongside 100 samples from healthy women. The concentration of GnRH was measured using an enzyme-linked immunosorbent assay (ELISA) kit to evaluate
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Tesis sobre el tema "Gonadotropin-Releasing hormones"

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Powell, R. C. "Evolution of the structure and function of vertebrate brain gonadotropin-releasing hormone." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/27201.

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In this study, the structure and function of gonadotropin-releasing hormone (GnRH) in different vertebrate species, in the classes Aves, Reptilia and Pisces was investigated. Acetic acid extracts were subjected to gel filtration chromatography and semipreparative high performance liquid chromatography (HPLC) to partially purify the GnRHs. The GnRH immunoreactivity was then characterized by analytical HPLC, and by assaying HPLC fractions by radioimmunoassay with region-specific antisera generated against mammalian GnRH, Gln⁸-GnRH and Trp⁷,Leu⁸-GnRH and assessing luteinizing hormone (LH)-releasi
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Von, Schalburg Kristian Robert. "The gonadotropin-releasing hormone gene : characterization, regulation and expression in two salmonids." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ36651.pdf.

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Von, Boetticher S. "Investigating the mechanism of transcriptional regulation of the gonadotropin-releasing hormone receptor (GnRHR) gene by dexamethasone." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1796.

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An, Beum-Soo. "Cross-talk between gonadotropin-releasing hormones and progesterone receptor in neuroendocrine cells." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/30705.

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Hypothalamic gonadotropin-releasing hormone (GnRH) is a decapeptide that plays a pivotal role in mammalian reproduction. It is hypothesized that progesterone (P4) may regulate GnRH I, GnRH II (a second form of GnRH) and GnRH I receptor (GnRH I R) at the transcriptional level. Alternatively, GnRHs may stimulate transactivation of the progesterone receptor (PR), thereby, modulating gonadotropin subunit gene expression. Treatment of human neuronal cells with P4 suppressed GnRH I R promoter activity. This P4-stimulated inhibition was enhanced when PR A was over-expressed. With respect to the
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Styger, Gustav. "The role of steroidogenic factor-1 (SF-1) in transcriptional regulation of the gonadotropin-releasing hormone (GnRH) receptor gene." Thesis, Stellenbosch : Stellenbosch University, 2001. http://hdl.handle.net/10019.1/52572.

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Thesis (MSc)--Stellenbosch University, 2001.<br>ENGLISH ABSTRACT: The GnRH receptor is a G-protein-coupled receptor in pituitary gonadotrope cells. Binding of its ligand, GnRH, results in synthesis and release of gonadotropin hormones luteinizing hormone (LH) and follicle stimulating hormone (FSH). Steroidogenic factor 1 (SF-1), a transcription factor, binds to specific sites in the promoter region of gonadotropin genes, and thus regulates transcription of these genes. The promoter region of the GnRHreceptor gene contains two SF-1-like binding sites, one at -14 to -8 (site 1) and anoth
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Wormald, Patricia J. "GnRH and neuropeptide regulation of gonadotropin secretion from cultured human pituitary cells." Doctoral thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/27168.

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Gonadotropin-releasing hormone (GnRH) and its superactive analogues are currently being used in the treatment of a number of endocrine disorders, such as endometriosis, precocious puberty, infertility and prostatic cancer. Selection of these analogues for clinical use have been previously based on their activities in animal models. This thesis has therefore investigated the binding characteristics of the human GnRH receptor, in comparison to those of the rat receptor, as well as the activities of a number of GnRH analogues for stimulating luteinising hormone (LH) and follicle stimulating hormo
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Dromey, Jasmin Rachel. "Elucidating novel aspects of hypothalamic releasing hormone receptor regulation." University of Western Australia. School of Medicine and Pharmacology, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0133.

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[Truncated abstract] G-protein coupled receptors (GPCRs) form one of the largest superfamilies of cell-surface receptors and respond to a vast range of stimuli including light, hormones and neurotransmitters. Although structurally similar, GPCRs are regulated by many diverse proteins, which allow the specific functions of each receptor to be carried out. This thesis focussed on two well-documented GPCRs, the thyrotropin releasing hormone receptor (TRHR) and gonadotrophin-releasing hormone receptor (GnRHR), which control the thyroid and reproductive endocrine pathways respectively. Although eac
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Kaplan, Hilton. "The control of prolactin secretion and the role of gonadotrophin releasing hormone in the production of concordant secretory spikes of luteinizing hormone and prolactin in the luteal phase of the menstrual cycle." Master's thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/27203.

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The control of prolactin secretion is a complex interaction of peptides and neurotransmitters acting either in an inhibitory or stimulating way to effect final secretion of this hormone from the lactotrope cell in the anterior hypothalamus. These factors may act either directly on the lactotrope cell or indirectly by changing either dopamine restraint of prolactin secretion or by modulating peptide substances or neurotransmitters higher up in the hypothalamus. Gonadal steroids may also modulate the effect of peptides or dopamine at the level of the lactotrope. Prolactin's major role in the fem
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De, Villiers Charon. "The effect of gonadotropin-releasing hormones (GnRH) I & II on sperm motility and acrosome status of the Vervet monkey (Chlorocebus aethiops) in vitro." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_9134_1253841818.

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<p>Gonadotropin Releasing Hormone (GnRH) is a hypothalmic decapeptide, which regulates mammalian gonadotropin secretions by binding to specific, high affinity receptors in the pituitary. Two forms of GnRH (GnRH I and GnRH II) are expressed in the brain of human and some primates. Even though primates have been used extensively in a variety of investigations in relation to the role of GnRH in reproduction, there is no evidence of any research to investigate the direct effect of GnRH on primate sperm.</p>
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Jeanne, Fabian. "Evοlutiοns des systèmes GΝRΗ et des hοrmοnes glycοprοtéiques dans les cοntrôles endοcrine et paracrine de la spermatοgénèse chez la rοussette, Scyliοrhinus canicula". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC225.

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La spermatogenèse est un processus hautement spécialisé de prolifération et de différenciation cellulaire conduisant à la production de spermatozoïdes haploïdes à partir de cellules souches spermatogoniales diploïdes. Chez les Gnathostomes, les fonctions testiculaires sont principalement contrôlées de façon endocrine par l’axe hypothalamo-hypophyso-gonadique (HHG) impliquant notamment les GnRHs hypothalamiques et les hormones gonadotropes, FSH et LH, dont l’émergence s’est produite à la racine des Vertébrés cartilagineux. De plus, des fonctions paracrines des GnRHs et de la thyrostimuline ont
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Libros sobre el tema "Gonadotropin-Releasing hormones"

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L, Barbieri Robert, and Friedman Andrew J, eds. Gonadotropin releasing hormone analogs: Applications in gynecology. Elsevier, 1991.

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Organon Round Table Conference (3rd 1992 Paris, France). GnRH, GnRH analogs, gonadotropins, and gonadal peptides: The proceedings of the third Organon Round Table Conference, Paris, 1992. Parthenon Pub. Group, 1993.

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Ferring Symposium on Brain and Pituitary Peptides (3rd 1985 Noordwijk, Netherlands). Pulsatile GnRH 1985: Proceedings of the 3rd Ferring Symposium, Noordwijk, September 11-13, 1985. Edited by Coelingh Bennink, Herman Jan Tymen, 1943-. Ferring, 1985.

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Jan, Horský. Gonadotropin-releasing hormone and ovarian function. Avicenum, Czechoslovak Medical Press, 1986.

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1958-, Parhar Ishwar S., ed. Gonadotropin-releasing hormone: Molecules and receptors. Elsevier, 2002.

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Goodman, Stephanie Robin. Effects of gonadotrophin releasing hormone on growth hormone release in the rat. s.n.], 1993.

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World, Congress on Fertility and Sterility (15th 1995 Bologna Italy). Treatment with GnRH analogs: Controversies and perspectives : the proceedings of a satellite symposium of the 15th World Congress on Fertility and Sterility held in Bologna, Italy, 15-16 September 1995. Parthenon Pub. Group, 1996.

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Nyean, Lee Chin, ed. Using gonadotropin-releasing hormone (GnRH) to improve dairy cattle conception rates in the tropics. HITAHR, College of Tropical Agriculture and Human Resources, University of Hawaii, 1989.

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Gore, Andrea C. GnRH, the master molecule of reproduction. Kluwer Academic Publishers, 2002.

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Gore, Andrea C. GnRH, the master molecule of reproduction. Kluwer Academic Publishers, 2002.

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Capítulos de libros sobre el tema "Gonadotropin-Releasing hormones"

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Sherwood, Nancy. "Gonadotropin-Releasing Hormones in Fishes." In Hormones and Reproduction in Fishes, Amphibians, and Reptiles. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1869-9_2.

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Moghissi, Kamran S. "Gonadotropin Releasing Hormones: Physiopathology and Clinical Applications." In The Brain as an Endocrine Organ. Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3480-7_1.

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Licht, Paul, and David A. Porter. "Role of Gonadotropin-Releasing Hormone in Regulation of Gonadotropin Secretion from Amphibian and Reptilian Pituitaries." In Hormones and Reproduction in Fishes, Amphibians, and Reptiles. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1869-9_3.

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Manji, Husseini K., Jorge Quiroz, R. Andrew Chambers, et al. "Gonadotropin-Releasing Hormone." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_1886.

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Naor, Zvi, and Rony Seger. "Gonadotropin-Releasing Hormone." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_2477-2.

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Naor, Zvi, and Rony Seger. "Gonadotropin-Releasing Hormone." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46875-3_2477.

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Naor, Zvi, and Rony Seger. "Gonadotropin-Releasing Hormone." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_2477.

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Bidlingmaier, M. "Gonadotropin-Releasing-Hormon." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_1312-1.

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Bidlingmaier, M. "Gonadotropin-Releasing-Hormon." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_1312.

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Colao, Annamaria, and Claudia Pivonello. "Gonadotropin Releasing Hormone (GnRH)." In Encyclopedia of Pathology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-28845-1_5110-1.

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Actas de conferencias sobre el tema "Gonadotropin-Releasing hormones"

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Ohlsson, M., A. J. W. Hsueh, and T. Ny. "HORMONE REGULATION OF THE FIBRINOLYTIC SYSTEM IN THE OVARY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644389.

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In the ovary, the release of oocytes from graafian follicles during hormone-induced ovulation has been found to be associated with substantial increases in follicular plasminogen activator (PA) activity. Most of the PA activity comes from the granulosa cells that have been shown to produce tPA, uPA as well as the type-1 PA-inhibitor,(PAI-1).We have studied the molecular mechanism of follicle stimulating hormone (FSH) and gonadotropin releasing hormone (GnRH) on the synthesis of tPA in primary cultures of rat granulosa cells. FSH and GnRH were both found to induce tPA in granulosa cells in a ti
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Sand, Sharon R., Catherine Klifa, Michael F. Press, et al. "Abstract 3557: Reduced ovarian hormones & reduced mammographic & MRI determined breast density inBRCAcarriers following a hormonal chemo-prevention regimen of gonadotropin releasing hormone agonist (GnRHA) & low-dose add-back estrogen & testosterone." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3557.

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"TOWARDS A NEW HOMOGENEOUS IMMUNOASSAY FOR GONADOTROPIN-RELEASING HORMONE BASED ON TIME-RESOLVED FLUORESCENCE ANISOTROPY." In International Conference on Biomedical Electronics and Devices. SciTePress - Science and and Technology Publications, 2011. http://dx.doi.org/10.5220/0003152001840188.

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Bibiari, Georgia, Agathi Nteli, Carmen Simal, et al. "Design and Synthesis of Gonadotropin Releasing Hormone (GnRH) Peptide Analogues Conjugated with Anthraquinone for Selective Immunosuppression." In 36th European Peptide Symposium. The European Peptide Society, 2022. http://dx.doi.org/10.17952/36eps.2022.065.

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Biniari, Georgia, Agathi Nteli, Carmen Simal, et al. "Design and Synthesis of Gonadotropin Releasing Hormone (GnRH) Peptide Analogues Conjugated with Anthraquinone for Selective Immunosuppression." In 36th European Peptide Symposium. The European Peptide Society, 2022. http://dx.doi.org/10.17952/36eps/36eps.2022.065.

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Biniari, Georgia, Agathi Nteli, Christos Markatos, et al. "Rational design, synthesis and evaluation of mitoxantrone conjugated with mutated Gonadotropin Releasing Hormone (GnRH) for the treatment of hormone-dependent cancer." In 37th European Peptide Symposium. The European Peptide Society, 2024. http://dx.doi.org/10.17952/37eps.2024.p1216.

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Pacucci, VA, F. Ceccarelli, G. Perrone, et al. "SAT0260 Ovarian function preservation with gonadotropin-releasing hormone analogues in patients with systemic lupus erythematosus treated with cyclophosphamide." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.6381.

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Neumann, Brooke, Jerome Check, Carrie Wilson, Donna Summers, and Kathleen Hollahan. "Evaluation of Outcome Following Oocyte Retrieval in Women with Marked Diminished Oocyte Reserve (DOR) Where the Only Oocyte Retrieved Was in a Metaphase I State." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.40_2023.

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OBJECTIVE: To determine if there is value in culturing a metaphase I oocyte to metaphase II followed by intracytoplasmic sperm injection (ICSI), fertilization, then embryo transfer (ET) in women with marked DOR. MATERIALS AND METHODS: A follicle stimulating hormone (FSH) receptor up-regulation technique was used in women whose day 3 serum FSH levels were &gt;12 mIU/mL and/or the serum anti-mullerian (AMH) level was 1&lt;ng/mL to mature antral follicle(s) to the dominant follicle stage (average diameter &gt;18) and serum estradiol (E2) &gt;200pg/mL when 10,000 IU human chorionic gonadotropin (h
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Kim, HJ, MH Lee, JE Lee, et al. "Abstract P1-12-09: The oncologic effect of a gonadotropin releasing hormone (GnRH) agonist for ovarian protection during breast cancer chemotherapy." In Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-p1-12-09.

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Xue, Yu, Youting Dong, and Xiaojun Chen. "PR001/#476 Gonadotropin-releasing hormone agonist (GnRH-a) plus letrozole in young women with early endometrial cancer: a prospective randomized controlled trial." In IGCS 2024 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/ijgc-2024-igcs.43.

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Informes sobre el tema "Gonadotropin-Releasing hormones"

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Zohar, Yonathan, Robert Langer, Shimon Hassin, Walton Dickhoff, Abigail Elizur, and Yoav Gothilf. A Novel Technology for the Manipulation of Fish Reproductive Cycles: Controlled Release of Gonadotropin Releasing Hormones. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7603811.bard.

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Xu, Dan, Xueying Zhou, Junfei Wang, Xi Cao, and Tao Liu. The Value of Urinary Gonadotropins in the Diagnosis of Central Precocious Puberty: A Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0076.

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Review question / Objective: Precocious puberty is defined as the onset of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. It can be differentiated into central precocious puberty (CPP) and peripheral precocious puberty, and it is more common in girls than in boys. CPP may result in a decreased final adult height, an early age at menarche, and psychological and health problems in adulthood. Gonadotropin-releasing hormone (GnRH) GnRH stimulation test has been indispensable in the diagnosis of CPP. GnRH stimulation test is not only invasive, time-consumin
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พงษ์เลาหพันธุ์, ศุภวิวัธน์, та ธีรพงศ์ ยะทา. การพัฒนาพาหะนำส่งยีนเหนี่ยวนำการตายของเซลล์แบบอะพอพโทซิสระดับนาโน เพื่อการคุมกำเนิดสัตว์เพศผู้แบบไม่ผ่าตัดทำหมัน : ต้นแบบเพื่อการคุมจำนวนประชากรสุนัขและแมวจรจัด. คณะสัตวแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2019. https://doi.org/10.58837/chula.res.2019.42.

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การศึกษาวิจัยนี้มีวัตถุประสงค์ เพื่อตรวจสอบการนำไปใช้ของอนุภาคไคโตซานระดับนาโนที่ถูกดัดแปลงให้มีคุณสมบัติเป็นตัวนำส่งยีนเหนี่ยวนำการตายแบบอะพอพโทซิสเข้าสู่เซลล์อัณฑะที่มีตัวรับฮอร์โมนโกนาโดโทรปินรีลิสซิ่ง โดยการออกแบบตัวนำส่งยีนนี้สามารถนำไปใช้ประโยชน์ในการทำหมันสัตว์เพศผู้แบบไม่ผ่าตัด การศึกษานี้ได้มีการรายงานผลของอนุภาคไคโตซานระดับนาโนเชื่อมติดกับฮอร์โมนโกนาโดโทรปินรีลิสซิ่ง (Gonadotropin Releasing Hormone-modified Chitosan; GnRH-CS) เพื่อนำส่งยีนอย่างมีเป้าหมาย และการใช้เปปไทด์โกนาโดโทรปินรีลิสซิ่งในการระบุเป้าหมายการนำส่งยีนไปสู่เซลล์ที่มีตัวรับฮอร์โมนโกนาโดโทรปินรีลิสซิ่ง (GnRH receptor;
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Gu, Li, Xurui Li, and Wentao Liu. Adverse cardiovascular effect following Gonadotropin-releasing Hormone (GnRH) antagonist versus GnRH agonist for Prostate Cancer Treatment: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0009.

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Yaron, Zvi, Abigail Elizur, Martin Schreibman, and Yonathan Zohar. Advancing Puberty in the Black Carp (Mylopharyngodon piceus) and the Striped Bass (Morone saxatilis). United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7695841.bard.

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Both the genes and cDNA sequences encoding the b-subunits of black carp LH and FSH were isolated, cloned and sequenced. Sequence analysis of the bcFSHb and LHb5'flanking regions revealed that the promoter region of both genes contains canonical TATA sequences, 30 bp and 17 bp upstream of the transcription start site of FSHb and LHb genes, respectively. In addition, they include several sequences of cis-acting motifs, required for inducible and tissue-specific transcriptional regulation: the gonadotropin-specific element (GSE), GnRH responsive element (GRE), half sites of estrogen and androgen
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