Literatura académica sobre el tema "Indigofera"
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Artículos de revistas sobre el tema "Indigofera"
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Rajesh, A. "IDENTIFIED PLANTS WHICH ARE BELONGS IN INDIGOFERA GENERA IN THOOTHUKUDI DISTRICT, TAMIL NADU, INDIA". International Journal of Research -GRANTHAALAYAH 8, n.º 11 (14 de diciembre de 2020): 287–95. http://dx.doi.org/10.29121/granthaalayah.v8.i11.2020.2455.
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The Indigofera are frequently shrubs, and some are small trees or herbaceous perennials or annuals. These have pinnate leaves. Racemes of flowers grow in the leaf axils, in hues of red, but there are a few white- and yellow-flowered species. The fruit is a legume pod of varying size and shape. Botanical description schedule as; Kingdom: Plantae, (unranked): Angiosperms, (unranked): Eudicots, (unranked): Rosids, Order: Fabales, Family: Fabaceae, Subfamily: Faboideae, Tribe: Indigofereae, Genus: Indigofera. 1620 plant name records match your search criteria Indigofera. The names found have these generic epithets: as accepted in the plant list online data base. That plants were; Indigofera argentea / I. articulate, Indigofera aspalathoides Vahl. Indigofera enneaphylla Linn. Indigofera glabra Linn. Indigofera glandulosa Willd. Indigofera linifolia Retz. Indigofera pulchella Roxb. Indigofera tinctoria Linn. Indigofera trifoliata Linn. Indigofera trita Linn. Books mentioned 04 species were not latest updated Plant List Online data base which were; Indigofera caerulea Roxb. Indigofera cordifolia. Indigofera frutescens. Indigofera hirsuta. According to the Results and Discussion this research revealed that, 20 species of Indigofera genera by the evidence of books and 04 species synonyms like updated latest in online data base. However, 16 species available in the Thoothukudi District 16 species available commonly and 04 species were rarely showed in Thoothukudi District by randomly field to all soil types of areas.
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Solehudin, Solehudin, Ade Syahrul M y Andi Tarigan. "Pengaruh Pemberian Pelet Mengandung Tepung Daun Indigofera terhadap Produktivitas Kambing Boerka Periode Bunting dan Laktasi". Jurnal Agripet 22, n.º 1 (1 de abril de 2022): 97–102. http://dx.doi.org/10.17969/agripet.v22i1.22235.
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ABSTRACT. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pelet mengandung tepung daun Indigofera terhadap produktivitas kambing Boerka periode bunting dan laktasi. Ternak yang digunakan adalah kambing Boerka bunting bulan keempat sebanyak 60 ekor dengan variasi paritas ke 2 dan 3 dan rataan bobot badan saat dikawinkan adalah 32,63±5,29 kg. Penelitian menggunakan Rancangan Acak Kelompok (RAK) dengan 3 perlakuan pakan dengan 20 kali ulangan: rumput lapang + Pelet komersil (R1); rumput lapang + pelet Indigofera 10% (R2); rumput lapang + pelet Indigofera 20% (R3). Parameter yang diukur adalah bobot badan anak lahir dan bobot badan anak prasapih (umur 3 bulan). Data dianalisis menggunakan Analysis of Variance (ANOVA ) satu arah dan dilanjutkan dengan Uji Jarak Berganda Duncan. Hasil analisis statistik menunjukkan bahwa pemberian tepung daun Indigofera 10% memberikan pengaruh nyata terhadap bobot lahir anak kambing betina dan tidak berbeda nyata terhadap parameter lainnya namun cenderung menurun pada pemberian tepung daun Indigofera 20%. Dapat disimpulkan bahwa penggunaan tepung daun Indigofera dalam pelet sampai 20% memberikan pengaruh yang tidak nyata terhadap produktivitas kambing Boerka periode bunting dan laktasi. (Effect of dietary pellet containing indigofera leaf meal on productivity of Boerka goat at pregnancy and lactating period) ABSTRAK. The research was aimed to investigate effect of dietary pellet containing Indigofera leaf meal on productivity of Boerka goat at pregnancy and lactating period. A total of 60 heads of Boerka goat who were pregnant at 4th, parity of 2nd and 3rd and average of body weight when mated were 32,63±5,29 kg. Research used randomized block design with 3 feed treatments and 20 replicated: native grass + commercial pellet (R1); native grass + Indigofera’s pellet 10% (R2); native grass + Indigofera’s pellet 20%. The parameter measured were body weight of lamb born and body weight of lamb at pre-weaning (3 month aged). Data were analyzed used Analysis of Variance (ANOVA) one way dan continued with Multiple’s Range Test of Duncan. The result of statistical analysis showed that dietary Indigofera leaf meal 10% gave significant effect on birth weight of female lamb and non significant effect on other parameters but tends to decreased in dietary Indigofera leaf meal 20%. It could be conclude that utilization of Indigofera leaf meal until 20% in pellet gave not significant effect on productivity of Boerka goat at pregnancy and lactating period.
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Chauhan, Vibha y Arun Pandey. "A revision of trifoliolate Indigofera (Tribe Indigofereae: Fabaceae) in India". Phytotaxa 220, n.º 1 (15 de julio de 2015): 1. http://dx.doi.org/10.11646/phytotaxa.220.1.1.
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A revision of trifoliolate Indigofera in India is provided based on field studies, and examination of herbarium specimens. In India, 11 species and 4 varieties of trifoliolate Indigofera are recognized: Indigofera barberi, I. deccanensis, I. glandulosa, I. glandulosa var. sykesii, I. karuppiana, I. pedicellata, I. prostrata, I. santapaui, I. thothathrii, I. tirunelvelica, I. trifoliata, I. trifoliata var. duthiei, I. trita, I. trita var. maffeii and I. trita var. purandharensis. Of 11 species, seven species and three varieties are endemic. A key to the species, description and illustrations are provided along with data on flowering and fruiting, distribution, habitat, chromosome number, and ethnobotanical uses.
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Rakhmawati, R., A. Sofiana, N. Indariyanti y R. J. M. Bokau. "Decreasing of Crude Fibre in Indigofera Leaves Flour Hydrolysed with Cellulase Enzyme as a Source of Feed Protein". IOP Conference Series: Earth and Environmental Science 1012, n.º 1 (1 de abril de 2022): 012060. http://dx.doi.org/10.1088/1755-1315/1012/1/012060.
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Abstract The problem of fish feed in Indonesia is currently dominated by import dependence on feed raw materials, especially fish meal and soybean meal. One alternative that currently can be chosen is indigofera leaves (Indigofera zollingeriana). The indigofera leaves used are indigofera leaves that have been cultivated by farmers in Kemiling District, Bandar Lampung City. Harvest is done at the age of 12 months. After harvesting, indigofera leaves are dried in the sun and the flouring process is carried out. Furthermore, indigofera and indigofera leaves were tested proximately and compared with commercial indigofera flour. In addition, the resulting indigofera leaf flour was hydrolyzed with cellulose enzyme at a dose of 10 g/kg for 5 days and a proximate test was carried out afterwards. The results showed leaf protein content of 19.95%, protein content of treated indigofera leaves flour 29.74% while protein content of commercial indigofera flour was 21.95% (dry weight). Meanwhile, the protein content of indigofera leaves flour which had been hydrolyzed with cellulose enzyme at a dose of 10 g/kg for 5 days increased to 31.30% and crude fiber decreased from 28.75% to 1.98%. The conclusion of this study is that the resulting indigofera leaves flour has the lowest crude fiber content and higher protein than indigofera leaves flour without hydrolysis of cellulose enzymes and commercial indigofera flour. Indigofera leaves flour hydrolyzed with cellulose enzymes resulted in a decrease in crude fiber and an increase in protein.
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Febriyanti, Tina Ayu, Ibrahim Hadist, Mega Royani y Ervi Herawati. "PENGARUH SUBSTITUSI BUNGKIL KEDELAI DENGAN Indigofera zollingeriana HASIL FERMENTASI TERHADAP SIFAT FISIK PELLET SETELAH MASA PENYIMPANAN SATU BULAN (Effect Of Soybean Meal Substitution With Indigofera Zollingeriana Fermented Products On Physical Properties Of Pellets After One Month Storage Period)". JANHUS: Jurnal Ilmu Peternakan Journal of Animal Husbandry Science 3, n.º 2 (20 de junio de 2019): 18. http://dx.doi.org/10.52434/janhus.v3i2.606.
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Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh dari substitusi bungkil kedelai dengan Indigofera zollingeriana hasil fermentasi terhadap sifat fisik pellet setelah masa penyimpanan satu bulan. Penelitian uji sifat fisik pellet dilaksanakan pada bulan April sampai September 2018 yang bertempat di Laboratorium terpadu Fakultas Pertanian UNIGA. Metode yang dilakukan yaitu Metode Eksperiental menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 4 ulangan, yaitu : R0 = Bungkil kedelai 26%, Indigofera fermentasi 0%; R1 = Bungkil kedelai 19,5%, Indigofera fermentasi 6,5%; R2 = Bungkil kedelai 13%, Indigofera fermentasi 13%; R3= Bungkil kedelai 6,5%, Indigofera fermentasi 19,5%; R4 = Bungkil kedelai 0%, Indigofera fermentasi 26%. Berdasarkan hasil penelitian menunjukkan bahwa penambahan Indigofera zollingeriana sampai level 26% tidak memberikan pengaruh yang nyata terhadap sifat fisik Pellet setelah masa penyimpanan satu bulan.
¬Kata-kata Kunci :Indigofera zollingeriana, Pellet, Sifat fisik, Penyimpanan
Abstract
This study aims to determine the effect of substitution of soybean meal with Indigofera zollingeriana fermentation on the physical properties of pellets after a one-month storage period. Research on physycal properties of pellets was conducted from April to September 2018 which is located at the UNIGA Agriculture Faculty Integrated Laboratory. The method used is the Experimental Method using a Completely Randomized Design (CRD) with 5 treatments and 4 replications, that is : R0 = 26% soybean meal, 0% fermented Indigofera; R1 = 19.5% soybean meal, fermented Indigofera 6.5%; R2 = 13% soybean meal, fermented Indigofera 13%; R3 = 6.5% soybean meal, fermented Indigofera 19.5%; R4 = 0% soybean meal, 26% fermented Indigofera. Based on the results of the study showed that addition of indigofera zollingeriana to level 26% did not have a significant effect on the physical properties of pellets after a one-month storage period
Keywords: Indigofera zollingeriana, Pellets, Physical properties, Storage
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Putri, Aulia Wara Arimbi, Janessa Angelica y Kirana Kartawidjaja. "PEWARNAAN DAN PEMBERIAN MOTIF ALAMI KAIN CELUP IKAT ITAJIME SHIBORI DENGAN EKSTRAK INDIGOFERA DAN TUNJUNG". Gorga : Jurnal Seni Rupa 10, n.º 2 (30 de diciembre de 2021): 541. http://dx.doi.org/10.24114/gr.v10i2.28490.
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The Increase in environtmentally friendly design products especially in fashion created by designers, artist and craftsmen in their work due to global trends and high demand for sustainable design products. Itajime shibori tie dyeing is one of the shape-resist techniques in textile design which usually using natural dyes in its application. The purpose of this research is to describe the process and to analyze the experimental result of natural dyeing and pattern from the combination of indigofera and tunjung extract on cotton silk fabrics with itajime shibori tie dyeing technique. The method used in this research is an experiment on different treatments to determine the after effect from tunjung and indigofera extract dipping which observed as the process of making new variation of dyed tie cloth with itajime shibori technique to obtain color change and pattern formation data using visual observations from soaking cloth in a tunjung solution overnight then in indigofera extract for 15 minutes in 3 stages (every 5 minutes) after that cloth ready for the final dyeing treatments which alternated between tunjung solution and indigofera extract for 1 stage of dipping (1) indigo-tunjung, (2) tunjung-indigo, (3) tunjung-indigo-tunjung, (4) tunjung-indigo-indigo, (5) tunjung-indigo-tunjung-indigo, (6) tunjung-indigo-indigo-tunjung dan (7) tunjung-indigo-tunjung-indigo-tunjung, the process shows there is an effect of color diggerences in stages of cloth dyeing between tunjung solution and indigofere extract from the fabric color from ivory white to light brown and the pattern color which change from dark blue to brownish green on the surface of cotton silk fabric which have the most dipping stage and ended it with tunjung.Keywords: indigofera, itajime, shibori, sustainable, tunjung. AbstrakProduk desain khususnya produk fesyen yang ramah lingkungan semakin marak diusung oleh desainer, seniman dan pengerajin dalam rancangannya karena pengaruh tren global dan juga peminat akan produk sustainable design yang sudah semakin tinggi. Kain celup ikat itajime shibori merupakan salah satu teknik penahan bentuk (shape-resist technique) dalam olah reka tekstil yang biasanya mempergunakan pewana alami dalam pengaplikasiannya. Tujuan penelitian ini adalah untuk mendeskripsikan proses dan menganalisis hasil eksperimen pewarnaan dan pemberian motif alami dari perpaduan ekstrak indigofera dengan larutan tunjung terhadap kain katun sutera dengan teknik celup ikat itajime shibori. Metode yang digunakan dalam penelitian adalah eksperimen terhadap perlakuan yang berbeda untuk mengetahui pengaruh yang ditimbulkan dari efek pencelupan larutan tunjung dan ekstrak indigofera yang diamati sebagai proses pembuatan ragam hias kain celup ikat dengan teknik itajime shibori untuk mendapatkan unsur perubahan warna dan pembentukan motif sebagai komponen data penelitian yang diamati menggunakan pengamatan visual dari hasil perendaman kain dalam larutan tunjung semalaman dengan durasi pencelupan pada ekstrak indigofera selama 15 menit dalam 3 tahapan celup setiap 5 menit yang setelahnya dilakukan perlakuan celup secara bergantian antara larutan tunjung dan ekstrak indigofera selama 1 tahapan celup yaitu (1) indigo-tunjung, (2) tunjung-indigo, (3) tunjung-indigo-tunjung, (4) tunjung-indigo-indigo, (5) tunjung-indigo-tunjung-indigo, (6) tunjung-indigo-indigo-tunjung dan (7) tunjung-indigo-tunjung-indigo-tunjung yang menunjukkan bahwa terdapat pengaruh perbedaan warna dalam tahapan celup larutan tunjung dan ekstrak indigofera mulai dari warna kain berwarna putih gading hingga cokelat muda dan warna motif biru tua menjadi hijau kecoklatan terhadap kain katun sutera pada proses pencelupan yang paling banyak dan diakhiri dengan larutan tunjung.Kata Kunci: berkelanjutan, indigofera, itajime, shibori, tunjung. Authors:Aulia Wara Arimbi Putri : Universitas Kristen MaranathaJanessa Angelica : Universitas Kristen MaranathaKirana Kartawidjaja : Universitas Kristen Maranatha References:Adalina, Y., Luciasih, A., & Andi, R. (2010). Sumber Bahan Pewarna Alami Sebagai Tinta Sidik Jari Pemilu. Pusat Penelitian dan Pengembangan Hutan dan Konservasi Alam: Badan Penelitian dan Pengembangan Kehutanan Departemen Kehutanan. Bogor.Ardana, Arixc. (2020). Budi Daya Indigofera untuk Pewarna Biru Alami Batik. https://www.cendananews.com/2020/05/budi-daya-indigofera-untuk-pewarna-biru-alami-batik.html (diakses tanggal 28 Oktober 2021).Edison, Lampu. (2019). Mengenal 5 Pewarna Tekstil Alami yang Banyak ditermukan di Indonesia. https://kumparan.com/lampu-edison/mengenal-5-pewarna-tekstil-alami-yang-banyak-ditemukan-di-indonesia-1rHSvF3jT8z/full (diakses tanggal 28 Oktober 2021).Handayani, A. P., & Mualimin, A. (2013). Pewarna Alami Batik dari Tanaman Nila (Indigofera) dengan Katalis Asam. Jurnal Bahan Alam Terbarukan, 2(1), 1-6.Kulsum, U. (2020). Sustainable Fashion as The Early Awakening of the Clothing Industry Post Corona Pandemic. International Journal of Social Science and Business, 4(3), 422-429.Lestari, K., & Riyanto, R. (2016). Pembuatan Pewarna Biru Dari Tanaman Indigofera tinctoria. Dinamika Kerajinan dan Batik: Majalah Ilmiah, (21), 7-15.Maziyah, S., Indrahti, S., & Alamsyah. (2019). Implementasi Shibori di Indonesia. Kiryoku Jurnal Studi Kejepangan, 3(4), 214-220.Muhafiz. (2020). Manfaat Tanaman Indigofera, Alternatif Pakan untuk Ternak. https://www.harapanrakyat.com/2020/07/manfaat-tanaman-indigofera/ (diakses tanggal 28 Oktober 2021).Putri, A. W. A. (2021). “Pewarnaan dan Pemberian Motif Alami Kain Celup Ikat Itajime Shibori dengan Ekstrak Indigofera dan Tunjung”. Hasil Dokumentasi Pribadi: 20 Agustus 2021, Bandung.Sholikah, Binti. (2020). UNS Luncurkan Pupuk Organik dari Limbah Pewarna Alami. https://www.republika.co.id/berita/qexuf5368/uns-luncurkan-pupuk-organik-dari-limbah-pewarna-alami (diakses tanggal 28 Oktober 2021).Thomas, Dana. (2019). Fashionopolis: The Price of Fast Fashion and The Future of Clothes. New York: Penguin Press.
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Murugan, Perumal, Vellingiri Ravichandran y Chidambaram Murugan. "Two new synonyms in the genus Indigofera (Leguminosae: Papilionoideae)". Indian Journal of Forestry 44, n.º 2 (15 de enero de 2022): 68–71. http://dx.doi.org/10.54207/bsmps1000-2022-q0b739.
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The recently described Indigofera kudiraimozhiensis Selvak. & Rajakumar and Indigofera thoothukudiensis Devi et al., are synonymised here under Indigofera tirunelvelica Sanjappa and Indigofera astragalina DC. respectively.
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Saijo, Sudradjat, Sudirman Yahya y Yayat Hidayat. "Adaptation of Indigofera zollingeriana (Miquel 1855) (Leguminosae : Indigofereae) Plant to Various Shade Levels". Jurnal Ilmu Pertanian Indonesia 23, n.º 3 (28 de diciembre de 2018): 240–45. http://dx.doi.org/10.18343/jipi.23.3.240.
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Jiménez Pérez, Nelly del Carmen, Eduardo Javier Moguel Ordóñez, María de los Ángeles Guadarrama Olivera, Mariana Ortiz Guadarrama y Mauricio Labastida Astudillo. "'Indigofera suffruticosa'". Kuxulkab' 27, n.º 59 (28 de diciembre de 2022): 67–69. http://dx.doi.org/10.19136/kuxulkab.a27n59.5535.
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Se presenta información taxonómica de la azucena 'Indigofera suffruticosa', así como la etimología, descripción morfológica sintética, nombres comunes, datos sobre su distribución con especial referencia a su presencia en el estado de Tabasco, hábitat, usos e ilustraciones originales de las partes de la planta.
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Rosyadi, Imron, Tati Rohayati y Titin Nurhayatin. "PENGARUH SUBSTITUSI BUNGKIL KEDELAI DENGAN Indigofera zollingeriana HASIL FERMENTASI DALAM RANSUM TERHADAP PERFORMA AYAM BROILER (Substitution Effect of Soybean Meal by fermented Indigofera zollingeriana in Ration on Performance of Broiler)". JANHUS: Jurnal Ilmu Peternakan Journal of Animal Husbandry Science 3, n.º 2 (30 de junio de 2019): 33. http://dx.doi.org/10.52434/janhus.v3i2.758.
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Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh substitusi bungkil kedelai dengan Indigofera zollingeriana hasil fermentasi dalam ransum terhadap konsumsi ransum, pertambahan bobot badan dan konversi ransum pada ternak ayam broiler. Penelitian ini menggunakan 80 ekor ayam broiler yang ditempatkan secara acak kedalam 20 kandang yang masing-masing terdiri dari 4 ekor ayam. Metode yang digunakan adalah metode eksperimental dengan menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 4 ulangan. Perlakuan yang digunakan yaitu R0 (bungkil kedelai 26% Indigofera zollingeriana hasil fermentasi 0%), R1 (bungkil kedelai 19,5% Indigofera zollingeriana hasil fermentasi 6,5%), R2 (bungkil kedelai 13% Indigofera zollingeriana hasil fermentasi 13%), R3 (bungkil kedelai 6,5% Indigofera zollingeriana hasil fermentasi 19,5%), dan R4 (bungkil kedelai 0% Indigofera zollingeriana hasil fermentasi 26%). Data penelitian dianalisis menggunakan analisis sidik ragam dan apabila hasilnya berbeda nyata dilanjutkan dengan Uji Jarak Berganda Duncan untuk melihat perbedaan antar perlakuan. Hasil penelitian menunjukkan substitusi bungkil kedelai dengan Indigofera zollingeriana hasil fermentasi berpengaruh terhadap konsumsi ransum, pertambahan bobot badan dan konversi ransum. Substitusi bungkil kedelai dengan Indigofera zollingeriana hasil fermentasi dalam ransum sampai taraf 13 persen tidak memberikan efek negatif terhadap performa ayam broiler.
Kata kunci : Indigofera zolingeriana, Performa, Ayam Broiler
Abstract
The research was aimed to determine the substituting of soybean meal by fermented Indigofera zollingeriana in diets on feed consumption, body weight gain, and feed conversion in broiler. This study using 80 broiler which were randomly placed into 20 cages consisting of 4 chickens. The method used is the experimental method using a Completely Randomized Design (CRD) with 5 treatments and 4 replications. The treatments used were R0 (soybean meal 26% fermented Indigofera zollingeriana 0%), R1 (soybean meal 19.5% fermented Indigofera zollingeriana 6.5%), R2 (soybean meal 13% fermented Indigofera zollingeriana 13%), and R3 (soybean meal 6.5% fermented Indigofera zollingeriana 19,5%), R4 (soybean meal 0% fermented Indigofera zollingeriana 26%). The research data were analyzed using analysis of variance and if the results were significantly different followed by Duncan's Multiple Range Test to see the differences between treatments. The results showed that substituting of soybean meal by fermented Indigofera zollingeriana had a significant effect on feed consumption, body weight gain, and feed conversion. The substituting of soybean meal by fermented Indigofera zollingeriana in diets until level 13 percent did not have a negative effect on the performance of broiler.
Keywords : Indigofera zollingeriana, Performance, Broiler
Tesis sobre el tema "Indigofera"
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Tjelele, Tlou Julius. "Dry matter production, intake and nutritive value of certain Indigofera species". Diss., Pretoria : [s.n], 2006. http://upetd.up.ac.za/thesis/available/etd-04042007-115406.
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Calvo, Tamara Regina [UNESP]. "Uso sustentável de biodiversidade brasileira - prospecção químico-farmacológica em plantas superiores: Alchornea glandulosa, Alchornea triplinervia (Euphorbiaceae), Indigofera truxillensis e Indigofera suffruticosa (Fabaceae)". Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/105841.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Neste trabalho foram estudadas a composição química e atividades farmacológicas de folhas de Alchornea glandulosa e Alchornea triplinervia (Euphorbiaceae) e partes aéreas de Indigofera truxillensis e Indigofera suffruticosa (Fabaceae), usadas na medicina popular brasileira no tratamento de problemas gástricos. Nos extratos clorofórmicos das espécies de Alchornea foram identificados estigmasterol, campesterol, sitosterol, lupeol, friedelan-3-ol, friedelan-3-ona e pteroginidina. O estudo dos extratos metanólicos das espécies de Alchornea forneceu ácido gálico, galato de metila, ácido carboxílico da brevifolina, amentoflavona, isocorilagina, miricetina 3-O-α-L-raminopiranosídeo, quercetina e quatro derivados glicosilados. Análise por FIA-ESI-IT-MS indicou a presença de derivados do ácido galoilquínico, elagitaninos e proantodicianidinas em A. triplinervia. Nos extratos clorofórmicos das espécies de Indigofera foram identificados índigo (indigotina) e indirubina. O extrato metanólico de I. truxillensis forneceu índigo, indirubina, indicana, pinitol, sitosterol 3-O-β-D-glicopiranosídeo e cinco derivados glicosilados do kaempferol, entre eles a substância inédita kaempferol 3-O-[α-Larabinopiranosil-( 2→1)-α-L-apiofuranosil] -7-O-α-L-raminopiranosídeo. O extrato metanólico de I. suffruticosa forneceu as mesmas substâncias descritas para I. truxillensis, exceto derivados do kaempferol, além do ácido gálico, alantoína e quatro derivados glicosilados da quercetina. Deste extrato também foram isoladas as substâncias inéditas 6’-metoxi 2, 5, 6-triidroxiisoindirubina, indigotina-3-O-β-D- glicopiranosídeo, dioxindol-3-O-β-D-glicopiranosídeo e quercetina 3-O-β-Dglicopiranosil-[( 4→1)-α-L-raminopiranosil]- (6→1)-α-L-apiofuranosídeo. O uso de FIA-ESI-ITMS possibilitou a identificação de glicerolipídeos, enquanto o emprego de HPLC-ESI-IT-MS permitiu...
In this work we studied the chemical composition and pharmacological activities of the leaves of Alchornea glandulosa and A. triplinervia (Euphorbiaceae), as well as aerial parts of Indigofera truxillensis and I. suffruticosa (Fabaceae), used in Brazilian folk medicine against gastric problems. In the chloroform extracts of the Alchornea species we identified stigmasterol, campesterol, sitosterol, lupeol, friedelan-3-ol, friedelan-3-one and pterogynidine. The study of the methanolic extracts of the Alchornea species afforded gallic acid, methyl gallate, brevifolin carboxylic acid, amentoflavone, isocorilagin, miricetin 3-O-α-L-rhamnopyranoside, quercetin and four glycosilated derivatives. Analyses by FIA-ESI-IT-MS helped to detect the presence of galloylquinic acid derivatives, ellagitannins and proanthodicyanidins in A. triplinervia. The chloroform extract of both Indigofera species led to the identification of indigo (indigotin) and indirubin. The methanolic extract of I. truxillensis gave indigo, indirubin, indican, pinitol, sitosterol-3-O-β-D-glucopyranoside and five glycosilated kaempferol derivatives, among them the new substance kaempferol 3-O-[β-D-apiofuranosyl-(1→2)-α-L- arabinopyranoside]-7-O-α- L-rhamnopyranoside. The methanolic extract of I. suffruticosa contained the same substances described for I. truxillensis, except for kaempferol derivatives, besides gallic acid, allantoin and four quercetin derivatives, besides the new substances 6’-methoxy-2,5,6- trihydroxiisoindirubin, indigotin-3-O-β-D-glucopyranoside, dioxindol-3-O-β-D-glucopyranoside and quercetin-3-O-[α- L-rhamnopyranosyl-(1→4)-[β-D-apiofuranosyl-(1→6)]-β-D-glucoyranoside. The use of FIAESI- IT-MS led the identification of glicerolipids, whereas the use of HPLC-ESI-IT-MS allowed to establish the chemical fingerprint of these species. The Alchornea species presented ...(Complete abstract click electronic access below)
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Calvo, Tamara Regina. "Uso sustentável de biodiversidade brasileira - prospecção químico-farmacológica em plantas superiores : Alchornea glandulosa, Alchornea triplinervia (Euphorbiaceae), Indigofera truxillensis e Indigofera suffruticosa (Fabaceae) /". Araraquara : [s.n.], 2007. http://hdl.handle.net/11449/105841.
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Orientador: Wagner VilegasBanca: Ian Castro-Gambôa
Banca: Fernando Batista da Costa
Banca: Mitsue Haraguchi
Banca: André Luiz Meleiro Porto
Resumo: Neste trabalho foram estudadas a composição química e atividades farmacológicas de folhas de Alchornea glandulosa e Alchornea triplinervia (Euphorbiaceae) e partes aéreas de Indigofera truxillensis e Indigofera suffruticosa (Fabaceae), usadas na medicina popular brasileira no tratamento de problemas gástricos. Nos extratos clorofórmicos das espécies de Alchornea foram identificados estigmasterol, campesterol, sitosterol, lupeol, friedelan-3-ol, friedelan-3-ona e pteroginidina. O estudo dos extratos metanólicos das espécies de Alchornea forneceu ácido gálico, galato de metila, ácido carboxílico da brevifolina, amentoflavona, isocorilagina, miricetina 3-O-α-L-raminopiranosídeo, quercetina e quatro derivados glicosilados. Análise por FIA-ESI-IT-MS indicou a presença de derivados do ácido galoilquínico, elagitaninos e proantodicianidinas em A. triplinervia. Nos extratos clorofórmicos das espécies de Indigofera foram identificados índigo (indigotina) e indirubina. O extrato metanólico de I. truxillensis forneceu índigo, indirubina, indicana, pinitol, sitosterol 3-O-β-D-glicopiranosídeo e cinco derivados glicosilados do kaempferol, entre eles a substância inédita kaempferol 3-O-[α-Larabinopiranosil-( 2→1)-α-L-apiofuranosil] -7-O-α-L-raminopiranosídeo. O extrato metanólico de I. suffruticosa forneceu as mesmas substâncias descritas para I. truxillensis, exceto derivados do kaempferol, além do ácido gálico, alantoína e quatro derivados glicosilados da quercetina. Deste extrato também foram isoladas as substâncias inéditas 6'-metoxi 2, 5, 6-triidroxiisoindirubina, indigotina-3-O-β-D- glicopiranosídeo, dioxindol-3-O-β-D-glicopiranosídeo e quercetina 3-O-β-Dglicopiranosil-[( 4→1)-α-L-raminopiranosil]- (6→1)-α-L-apiofuranosídeo. O uso de FIA-ESI-ITMS possibilitou a identificação de glicerolipídeos, enquanto o emprego de HPLC-ESI-IT-MS permitiu...(Resumo completo, clicar acesso eletrônico abaixo)
Abstract: In this work we studied the chemical composition and pharmacological activities of the leaves of Alchornea glandulosa and A. triplinervia (Euphorbiaceae), as well as aerial parts of Indigofera truxillensis and I. suffruticosa (Fabaceae), used in Brazilian folk medicine against gastric problems. In the chloroform extracts of the Alchornea species we identified stigmasterol, campesterol, sitosterol, lupeol, friedelan-3-ol, friedelan-3-one and pterogynidine. The study of the methanolic extracts of the Alchornea species afforded gallic acid, methyl gallate, brevifolin carboxylic acid, amentoflavone, isocorilagin, miricetin 3-O-α-L-rhamnopyranoside, quercetin and four glycosilated derivatives. Analyses by FIA-ESI-IT-MS helped to detect the presence of galloylquinic acid derivatives, ellagitannins and proanthodicyanidins in A. triplinervia. The chloroform extract of both Indigofera species led to the identification of indigo (indigotin) and indirubin. The methanolic extract of I. truxillensis gave indigo, indirubin, indican, pinitol, sitosterol-3-O-β-D-glucopyranoside and five glycosilated kaempferol derivatives, among them the new substance kaempferol 3-O-[β-D-apiofuranosyl-(1→2)-α-L- arabinopyranoside]-7-O-α- L-rhamnopyranoside. The methanolic extract of I. suffruticosa contained the same substances described for I. truxillensis, except for kaempferol derivatives, besides gallic acid, allantoin and four quercetin derivatives, besides the new substances 6'-methoxy-2,5,6- trihydroxiisoindirubin, indigotin-3-O-β-D-glucopyranoside, dioxindol-3-O-β-D-glucopyranoside and quercetin-3-O-[α- L-rhamnopyranosyl-(1→4)-[β-D-apiofuranosyl-(1→6)]-β-D-glucoyranoside. The use of FIAESI- IT-MS led the identification of glicerolipids, whereas the use of HPLC-ESI-IT-MS allowed to establish the chemical fingerprint of these species. The Alchornea species presented ...(Complete abstract click electronic access below)
Doutor
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Andreazza, Nathalia Luiza 1984. "Prospecção de metabólitos secundários e fitoderivados bioativos em Guatteria blepharophylla (Annonaceae) e Indigofera truxillensis (Fabaceae) para aplicação em terapia fotodinâmica e desenvolvimento de procedimentos analíticos". [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/315309.
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Orientador: Marcos José SalvadorTese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: Neste trabalho realizou-se estudo físico, químico e biológico para a prospecção de metabólitos secundários e fitoderivados em Guatteria blepharophylla (Annonaceae) e Indigofera truxillensis (Fabaceae) para aplicação em Terapia Fotodinâmica (PDT). A caracterização fitoquímica dos extratos metanólicos das espécies estudadas resultou no isolamento de cinco alcaloides isoquinolínicos de G. blepharophylla e um alcaloide bis-indólico de I. truxillensis. A investigação fotofísica dos extratos, frações e das substâncias isomoschatolina e índigo, revelou perfis de absorção na região entre 600 a 800 nm. Nas análises fotoquímicas, os extratos e fração alcaloídica de G. blepharophylla apresentaram resultados sugestivos quanto a produção de oxigênio singleto, assim como a substância isomoschatolina. Já em ensaio microbiológico in vitro com o emprego de substâncias supressoras de espécies reativas de oxigênio, observou-se a prevalência do mecanismo fotoquímico do tipo II para a isomoschatolina e do tipo I para o índigo. Nos ensaios biológicos de PDT antimicrobiana e antitumoral com os extratos, frações e as substâncias isoladas isomoschatolina e índigo observaram-se, para todas as estas amostras-teste, resultados efetivos na inativação de algumas das cepas indicadoras com redução do crescimento microbiano (UFC/ml) superior a 90%, assim como diminuição da sobrevida celular para as linhagens humanas de fibroblasto (3T3) e melanoma (UACC-62), sendo observado efeito em menores concentrações somente para UACC-62 quando associado à irradiação laser (660nm). Em ensaio biológico na presença das substâncias CaCl2 e MgCl2, a ação biocida dos alcaloides isomoschatolina e índigo, na fotoinativação da cepa Escherichia coli ATCC 10799 foi intensificada se comparado aos grupos controles. Portanto o conjunto de resultados observados sugerem que os extratos brutos e frações alcaloídicas das duas plantas estudadas e os alcaloides isomoschatolina e índigo apresentaram fotoatividade frente a bactérias, leveduras e frente à cultura de células de melanoma em concentração subinibitória. Na análise da interação dos alcaloides fotossensibilizantes berberina e isomoschatolina com LDL em modelos celulares, a caracterização dos complexos alcaloide/LDL permitiu identificar uma primeira classe de fixação, denominada classe P, a partir de alterações na fluorescência da apoproteína B-100. Para berberina e isomoschatolina verificou-se que cerca de 250 e 135 moléculas se complexam a porção proteica da partícula de LDL e proximidades, apresentando constante de afinidade iguais a 1,05.108 M-1 e 5,06.107 M-1, respectivamente. Uma segunda classe de fixação, chamada de classe L, determinada somente para a berberina, foi caracterizada a partir de alterações na fluorescência deste alcaloide e correspondeu a fixação de cerca de 80 moléculas de berberina na porção lipídica da partícula de LDL, com uma constante de afinidade de 7,10.107 M-1. Estes valores revelam que o processo predominante de interação da berberina com o LDL é a fixação de classe P. Nos ensaios em nível celular, realizados com a berberina, verificou-se que a sua complexação com o LDL não prejudica o seu reconhecimento pelos receptores apoproteína B/E da superfície membranar das células U87MG e que a sua internalização pode ocorrer associada o LDL pela via de endocitose. No entanto, não foi verificado acumulo de berberina nos lisossomos, mas apenas nas mitocôndrias, o que sugere que após a internalização, o alcaloide rapidamente sofre um processo de redistribuição intracelular. Para células cultivas em Ultroserum G, observou-se aumento da produção de produtos da peroxidação lípidica nas células tratadas com berberina complexada em relação àquelas tratadas com o alcaloide livre, nas doses de irradiação de 50 e 100 J/cm2. Todas estas evidências revelam a possibilidade de complexação de ambos os alcaloides com o LDL como molécula carreadora para aplicação em PDT antitumoral, sendo que para berberina a associação não só aumenta sua incorporação celular, assim como sua efetividade como agente fotoativo
Abstract: In this work it was carried out chemical and biological studies for secondary metabolites and phyto-derivatives prospecting from Guatteria blepharophylla (Annonaceae) and Indigofera truxillensis (Leguminosae) for antimicrobial and antitumor photodynamic therapy (PDT) application. The phytochemical characterization of the methanol extracts from both species resulted in the isolation of five isoquinoline alkaloids from G. blepharophylla, isomoschatoline, O-methylmoschatoline, liriodenine, subsessiline and lysicamine, and one bis-indole alkaloid, indigo, from I. truxillensis. Photophysical characterization of crude extracts, fractions and the substances isomoschatoline and indigo showed absorption profiles in the region between 600 to 800 nm and fluorescence emission when excited at their absorption wavelenght. In photochemical analysis, at 1,3-DPBF probe assay, crude extracts and alkaloidal fraction from G. blepharophylla showed positive results regarding singlet oxygen production, as well as isomoschatoline. At in vitro microbiological assay with reactive oxygen species suppressors, it was observed the prevalence of type II photochemical mechanism for isomoschatoline and type I for indigo, as also suggested by 1,3- DPBF assay results. In the antimicrobial and antitumor PDT biological assays, with crude extracts, fractions, isomoschatoline and indigo, effective results for microbial strains inactivation were found with microbial growth reduction (CFU/mL) superior to 90%, as well as decreased cell survival of human fibroblast (3T3) and melanoma (UACC-62) cell lines, in which this effect for the latter, was observed at lower concentrations when combined with laser irradiation. It was also found that both isomoschatoline and indigo exhibit enhanced photodynamic antimicrobial activity against Gram-negative bacteria (Escherichia coli ATCC 10799 strain) in comparison to control groups, when CaCl2 and MgCl2 additives were employed. Therefore, in light of all assays results it is suggested that crude extracts and alkaloid fractions from both plant species and the alkaloids isomoschatoline and indigo showed photoactivity against bacteria and yeasts strains and against melanoma human cell line at sub-inhibitory concentration when associated with laser irradiation at 660 nm. At interaction studies between photosensitizing alkaloids berberine and isomoschatoline with LDL and cellular models, changes in LDL¿s Apoprotein B-100 fluorescence allowed the identification of a first class of substances fixation in this particle called, P fixation class. For berberine and isomoschatoline it was found that about 250 and 135 molecules, respectively complexes to LDL¿s protein portion and its vicinity, leading to affinities constants equals to 1,05.108 M-1 and 5,06.107 M-1, respectively. A second fixation class, the L fixation class, accessed only for berberine, was obtained by changes in the alkaloid fluorescence and correspond to 80 molecules attached to LDL¿s lipid portion, leading to affinity constant equal to 7,10.107 M-1. These results reveal that the predominant process of berberine interaction with LDL is by P fixation class. At cellular level assays, performed only with berberine, it was found that the alkaloid complexation with LDL did not affect LDL recognition by apoprotein B/E membrane surface receptors of U87MG cells and that berberine internalization may occur associated with the particle via LDL endocytosis. However, there was no accumulation of berberine found in lysosomes. Mitochondria accumulation was observed suggesting that, after internalization, this alkaloid undergoes rapid intracellular redistribution process. At cells cultured with Ultroserum G and treated with complexed berberine it was also observed an increase in lipid peroxidation in comparison with cells incubated with free BBR, under irradiation doses of 50 to 100 J/cm2. All these evidences indicate the possibility of both alkaloids complexation with LDL as a carrier molecule for antitumor PDT application and, for berberine, this association not only increases its cellular uptake, as well as its effectiveness as photoactive agent
Doutorado
Biologia Vegetal
Doutora em Biologia Vegetal
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Ferreira, Fernanda Peres. "Gêneros tóxicos da nossa flora: química e biologia". Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/60/60138/tde-02102012-102327/.
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O conhecimento de plantas tóxicas tem apresentado um grande papel para a sociedade. Seus estudos são importantes desde que são responsáveis por diferentes enfermidades, e até mesmo mortes por envenenamento, assim como por tornar possível o conhecimento de moléculas bioativas, as quais muitas delas se tornaram importantes na terapêutica atual. Vários são os exemplos de fármacos que estão no mercado, provenientes da observação humana de sinais de intoxicação após a ingestão de plantas capazes de metabolizar essas estruturas. Portanto, o estudo de plantas tóxicas está intimamente relacionado com a saúde de homens e de animais. Todavia, estão envolvidas também em aspectos econômicos, se for considerado os milhões de ruminantes que morrem a cada ano pelas suas ingestões. O envenenamento do gado, ocasionado por essas espécies é um sério problema, principalmente no Brasil, onde aproximadamente um milhão de animais morre por ano, devido à ingestão dessas plantas. Após avaliação de diversas plantas, consideradas tóxicas ou potencialmente tóxicas para o gado, observouse a presença de poucos estudos referentes à composição dos metabólitos secundários para várias espécies. Este trabalho apresentou como objetivos realizar um screening químico das espécies tóxicas Riedeliella graciliflora, Indigofera truxillensis e Crotalaria micans, além das espécies pertencentes a gêneros tóxicos Senna pendula, Senna splendida, Senna aculeata e Ipomoea chiliantha, envolvendo estudos farmacognósticos, além de análises espectroscópicas (RMN de 1H) e observação do perfil químico em CLAE-UV-DAD, CG-EM. Tal screening permitiu selecionar as espécies para a realização de estudo químico mais detalhado. Também foram propostas as avaliações da atividade citotóxica dos extratos e frações, a partir de ensaios utilizando Artemia salina, e das atividades antimicrobianas, antitumorais, anti-alérgica e tripanocida. Quanto aos ensaios de citotoxicidade dos extratos para Artemia salina, apesar destes não se apresentarem muito ativos, observou-se maior toxicidade de Crotalaria micans, Senna splendida e Indigofera truxillensis, nas quais todos os microcrustáceos apresentaram comprometimento da motilidade ou morte nas concentrações 500 e 1000 ?g/ml. No estudo químico de I. chiliantha foram identificados triterpenos, alcoóis, ácidos e ésteres graxos, derivados fenilpropanoides, flavonoide, além de calisteginas, as quais são alcaloides nortropânicos, e uma resina glicosídica ainda não descrita na literatura. As calisteginas são inibidoras de glicosidases, sendo tal atividade atribuída à toxicidade apresentada pelas espécies do gênero Ipomoea, ao gado. Já as resinas glicosídicas têm apresentado efeito catártico drástico, além de citotoxicidade, podendo contribuir para a toxicidade das espécies do gênero. No estudo químico de R. graciliflora, foram identificados triterpenos, esteroides, ácidos graxos, tocoferol, flavonoides C-glicosídeos e O-glicosídeos, benzenoide, além de quatro isoflavanas, sendo três inéditas na literatura e a outra inédita como produto natural. A fração diclorometânica de R. graciliflora, a partir da qual foram isolados os isoflavanóis descritos, apresentou-se muito ativa contra as linhagens celulares tumorais SP-295, HCT-8 e MDA-MB-435. No estudo químico de I. truxillensis, foram identificados triterpeno, esteroides, ácidos e ésteres graxos, benzenoides, flavonoides O-glicosídeos, e o alcaloide indoxil-?-glicopiranosídeo, ao qual ii têm sido atribuído ser o responsável por toxicidade urêmica, em ratos, devido ao seu produto de biotransformação, indoxil (3-hidroxindol) sulfato, ser uma toxina urêmica. Devido os sintomas de intoxicação apresentados pelo gado que ingeriram esta planta estarem relacionados à toxicidade nos rins, a presença deste alcaloide parece ter um importante papel em sua toxicidade. No estudo químico de S. splendida e S. pendula, foram identificados ácidos e ésteres graxos, tocoferóis, triterpeno, esteroides, flavonóis e antraquinona. Nenhuma destas substâncias parece estar relacionada à toxicidez. Quanto aos ensaios de atividade citotóxica frente às linhagens celulares tumorais, o extrato bruto de C. micans apresentou atividade moderada frente à linhagem celular SF-295. Quanto aos ensaios antimicrobianos, nenhum dos extratos brutos apresentou-se ativo. Porém, as frações de S. splendida provenientes das partições apresentaram atividade contra as bactérias Klebsiela pneumoniae/13883 e Proteus mirabilis/29906. Quanto aos ensaios para avaliação da atividade anti-alérgica, os derivados fenilpropanoides isolados de I. chiliantha apresentaram-se ativos. Quanto aos ensaios para avaliação da atividade tripanocida, apresentaram atividade o extrato etanólico bruto de R. graciliflora e a fração em acetato de etila de S. splendida.Knowledge about toxic plants has played a fundamental role in our society. Investigation of such plants is important, because they are responsible for a wide range of malaise and even death by poisoning. Moreover, gaining insight into active biomolecules is paramount, since many of these compounds have become extremely relevant in current therapeutics. There are various examples of commercially available drugs originated from the human observation of signs of intoxication following ingestion of plants capable of metabolizing these structures. Therefore, the study of toxic plants is closely related to human and animal health. Economic issues are also involved, if one considers the millions of ruminants that die every year due to toxic plant ingestion. Cattle poisoning owing to these species is a serious matter, especially in Brazil, where approximately a million animals die due to poisoning by ingested plants every year. After evaluation of several plants deemed toxic or potentially toxic to cattle, we have observed that there are few works on the composition of secondary metabolites from these species. Therefore, the present investigation aimed at the chemical screening of the toxic species Riedeliella graciliflora, Indigofera truxillensis, and Crotalaria micans, and of species belonging to the toxic genera Senna pendula, Senna splendida, Senna aculeate, and Ipomoea chiliantha, by means of pharmacodiagnostic studies , spectroscopic analysis (1H NMR), and examination of the chemical profile by HPLC-UV-DAD, GC-MS. Such screening allowed for selection of the species to be used in a more detailed chemical study. Assessment of the cytotoxic activity of the extracts and fractions was proposed on the basis of assays employing Artemia salina and evaluating its antimicrobial, antitumor, anti-allergic, and trypanocidal activities. Although the extracts from Artemia salina did not exhibit pronounced cytotoxicity, larger toxicity was detected for Crotalaria micans, Senna splendida, and Indigofera truxillensis, in the presence of which all the crustraceans presented reduced motility or death at concentrations of 500 and 1000 ?g/ml. The chemical investigation of I. chiliantha enabled identification of triterpenes, alcohols, fatty acids and esters, phenylpropanoid derivatives, flavonoids, as well as calystegines, which are nortropane alkaloids, and a resin glycosidic not yet described in the literature. Calystegines are inhibitors of glycosidases, and this action is attributed to the toxicity displayed by species of the genus Ipomoea against cattle. As for resins glycosidic, besides cytotoxicity they also present a drastic cathartic effect, thereby contributing to the toxicity inherent to the species of this genus. The chemical study of R. graciliflora allowed for identification of triterpenes, steroids, fatty acids, tocopherol, flavonoids, C-glycosides and O-glycosides, benzenoids, in addition to four isoflavans, three of which have not been reported in the literature yet and one of which is novel as natural product. The dichloromethane fraction of R. graciliflora, from which the described isoflavanols were isolated, was very active against the tumor cell strains SP-295, HCT-8, and MDA-MB- 435. The chemical investigation of I. truxillensis revealed the existence of triterpene, steroids, fatty acids and esters, benzenoids, flavonoid O-glycosides, and the alkaloid indoxyl-?-glucopiranoside, to which uremic toxicity in rats has been attributed. This is because of its biotransformation product indoxyl (3-hydroxindol) sulfate, which is known to be a uremic toxin. Because the intoxication symptoms detected in the cattle that have ingest this plant are related to kidney toxicity, the presence of this alkaloid seems to play iv an important part in the toxicity of this species. The chemical screening of S. splendida and S. pendula demonstrated the existence of fatty acid and esters, flavonols, and anthraquinone. None of these compounds seem to be related to toxicity. As for the assays regarding the cytotoxic activity against tumor cell strains, the crude extract of C. micans was moderately active against the cell strain SF-295. With respect to the antimicrobial assays, none of the crude extracts displayed activity. Nevertheless, S. splendida fractions originated from partitions presented activity against the bacteria Klebsiela pneumoniae/13883 and Proteus mirabilis/29906. Concerning the assays evaluating the anti-allergic action, the phenylpropanoid derivatives isolated from I. chiliantha exhibited interesting properties. When it comes to the trypanocidal activity, the crude ethanolic extract from R. graciliflora and the acetyl acetate fraction of S. splendida were active.
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Raphael, Cardoso Vieira Jeymesson. "Indigofera suffruticosa Mill: um meio terapêutico alternativo anti-câncer". Universidade Federal de Pernambuco, 2007. https://repositorio.ufpe.br/handle/123456789/9068.
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Previous issue date: 2007Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Indigofera suffruticosa Mill (Fabeceae) ocorre em abundância no nordeste brasileiro e tem intenso uso popular no tratamento de infecções, inflamações e outros processos. Para explorar o potencial desta planta e dar uma base científica a sua utilização, este trabalho experimental foi desenvolvido investigando-se a presença de compostos químicos majoritários em extratos de folhas de I. suffruticosa obtidos por infusão e os efeitos citotóxico e antitumoral dos extratos de folhas de I. suffruticosa obtidos por infusão e maceração. O material utilizado foi obtido a partir de um screening fitoquímico de folhas onde foram evidenciados protocolos extrativos de identificação de moléculas majoritárias presentes nas folhas. As moléculas majoritárias identificadas foram: alcalóides, polifenóis, terpenóides, açúcares e índigo. O extrato aquoso não exibiu citotoxicidade contra células HEp-2 (Human Larynx Epidermoid Carcinoma Cells) pelo método MTT. A atividade antitumoral dos extratos aquosos por infusão (64,53%) e maceração (62,62%) frente ao Sarcoma 180 em camundongos na dose de 50 mg/kg i.p., baseada na baixa ordem de toxicidade, foi comparada com o grupo controle que mostrou desenvolvimento tumoral de 100%. Os referidos extratos produziram reações comportamentais nos sistemas nervosos central e periférico sem apresentar alteração de massa muscular. Considerando a baixa ordem de toxicidade e a alta efetividade na inibição do crescimento de tumor sólido, o extrato aquoso de folhas de I. suffruticosa pode ser usado como agente terapêutico alternativo anticâncer
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SILVA, Cleideana Bezerra da. "Avaliação da atividade antitumoral em extrato de Indigofera suffruticosa Mill". Universidade Federal de Pernambuco, 2008. https://repositorio.ufpe.br/handle/123456789/1309.
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Previous issue date: 2008Indigofera suffruticosa Mill é uma arbusto da família Fabaceae conhecido popularmente como anil. É uma planta distribuída mundialmente, sendo utilizada na medicina popular contra diversos problemas de saúde. Este estudo avaliou a ação toxicológica do extrato aquoso de folhas de I. suffruticosa, bem como a atividade antitumoral sobre células de carcinoma de Ehrlich (EC) e a influência desse extrato sobre os níveis séricos de colesterol total e triglicerídeos em camundongos. Foram realizados ensaios de toxicidade aguda por via oral e via intraperitoneal em camundongos machos, onde se verificou efeitos estimulantes seguidos de efeitos depressores, após a administração do extrato. As doses utilizadas foram de 490 a 850 mg/kg por via intraperitoneal, onde foi estimado o valor da DL50 em 750,6 mg/kg e 1000 a 5000 mg/kg por via oral, entretanto, nenhuma morte foi notificada por esta via de administração, somente alguns sinais tóxicos. A toxicidade do extrato também foi testada frente à Artemia salina, que mostrou uma CL50 de 127μg/mL. Tratamento de camundongos albinos suíços normais (n = 5) com extrato de I. suffruticosa com dose de 50 e 100 mg/kg, administrada intraperitonealmente, não apresentou diferença significante nos níveis séricos de colesterol total e triglicerídeos. Após o tratamento com I. suffruticosa por via intraperitoneal, notou-se uma redução significativa (p < 0,001) no tamanho dos tumores ( 75,5% e 63,9%), quando utilizou-se doses de 50 e 100 mg/kg, respectivamente. A I. suffruticosa possui moderada toxicidade e exibiu uma significante atividade antitumoral em camundongos portadores de EC, indicando que a mesma possui propriedades medicinais
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NASCIMENTO, Weber Melo. "Potencial antioxidante de extrato e proteína de folhas de Indigofera suffructicosa". Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/26642.
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CNPq
Plantas são importantes fontes de moléculas bioativas com potencial antioxidante. Indigofera suffruticosa é uma leguminosa encontrada na região do Semi-Árido e Agreste Pernambucano, sendo utilizada popularmente como antiespasmódico, sedativo e diurético. O objetivo deste estudo foi avaliar o efeito antioxidante do extrato e de proteína de folhas de I. suffruticosa. O extrato aquoso foi obtido a partir da homogeneização constante do pó de folhas secas com água destilada, o qual foi liofilizado. Alíquotas do liofilizado foram submetidas à cromatografia de afinidade para isolamento de material proteico ligado a matriz cromatográfica. A massa molecular aparente bem como o ponto isoelétrico da proteína foi avaliada por eletroforese bidimensional. A análise fitoquímica do extrato e da proteína foi realizada utilizando cromatografia em camada delgada. A atividade antioxidante in vitro do extrato e da proteína foi avaliada pelo método do 2,2-difenil-1-picrilhidrazil (DPPH), bem como foi investigado o conteúdo fenólico total tanto no extrato quanto na proteína. Os resultados demonstraram que a proteína isolada possui massas molecular aparente de 31,7 KDa e ponto isoelétrico 8,13. A triagem fitoquímica da proteína demonstrou ausência em metabolitos secundários e do extrato revelou a presença de flavanóides e ácido gálico. Tanto o extrato quanto a proteína exibiram a presença de conteúdo fenólico, o qual foi considerado moderado. Extrato e proteína (1 mg/mL) exibiram potencial antioxidante. A proteína mostrou maior atividade (52,52 %) que o extrato (35,21 %) e foi moderada em relação ao padrão antioxidante (71,48 %). A atividade antioxidante contra o DPPH pela proteína obtida de extrato aquoso de folhas de I. suffruticosa é de interesse, pois se trata de um produto de origem vegetal com promissora aplicacação biotecnológica.
Plants are important sources of bioactive molecules with antioxidant potential. Indigofera suffruticosa is a legume found in the semiarid region and Agreste Pernambucano, is popularly used as an antispasmodic, sedative and diuretic. The aim of this study was to evaluate the antioxidant potential of the extract and protein leaves of I. suffruticosa. The aqueous extract was obtained from the homogenization contained in dried powder with distilled water, which was lyophilized. Lyophilized aliquots were subjected to affinity chromatography for isolation of proteins material bound to the chromatographic matrix. The apparent molecular weight as well as the isoelectric point of the protein was assessed by two-dimensional electrophoresis. The phytochemical analysis of the extract and the protein was performed using thin layer chromatography. Antioxidant activity in vitro of the extract and the protein was evaluated by the methods of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) as well as was investigated the total phenolic content both in the extract and in the protein. The results showed that the isolated protein has apparent molecular mass of 31.7 KDa and isoelectric point 8.13. Phytochemical screening of the protein showed absence of secondary metabolites and the extract showed the presence of flavonoids and gallic acid. Both the extract and the protein showed the presence of phenolic content, which was considered moderate. Extract and protein (1 mg/mL) exhibited antioxidant potential. The protein showed higher activity (52.52%) than the extract (35.21%) and was moderate in relation to the antioxidant standard (71.48%). The antioxidant activity against DPPH from protein obtained of the aqueous extract of I. suffruticosa leaves is of interest because it is a product of plant origin , with promising biotechnological application.
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ANDRADE, Suanni Lemos de. "Produção de nitrosamina por leveduras isoladas em neoplasia maligna bucal e atividade antifúngica do fluconazol e extrato de Indigofera suffruticosa". Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/25640.
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FAPEAM
Neoplasia maligna bucal se desenvolve a partir do revestimento epitelial da mucosa da boca. De acordo com a Organização Mundial de Saúde, ocorrem 640.000 casos de câncer oral por ano, sendo o sexto tipo mais incidente e responsável por 10% de todos os tumores malignos no mundo. Diversos fatores estão envolvidos na carcinogênese, incluindo as infecções por micro-organismos. As leveduras podem desencadear mecanismos cancerígenos por metabolizar substâncias cancerígenas, como as nitrosaminas. Infecções fúngicas em pacientes portadores de câncer bucal são induzidas pelo desequilíbrio imunológico devido à terapia antineoplásica, assim como pela virulência do agente etiológico. A virulência das espécies de Candida pode ser determinada pela capacidade de aderência, proliferação, produção de enzimas como a protease, formação de tubo germinativo e resistência a drogas antifúngicas, o que torna importante a busca de novas alternativas terapêuticas, como a planta Indigoffera suffruticosa. O objetivo deste trabalho é estudar a relação da produção de nitrosamina, testar a susceptibilidade antifúngica in vitro de drogas convencionais e do extrato de I. suffruticosa em leveduras isoladas de neoplasia maligna bucal. Amostras foram isoladas de lesões malignas bucais através de biópsia, em seguida processadas para a realização de exame direto e cultura. As leveduras isoladas foram purificadas e posteriormente identificadas através da taxonomia clássica e automação. Em seguida, foram verificados fatores de virulência das leveduras quanto à produção de tubo germinativo, aderência às células epiteliais orais, detecção de protease e sensibilidade a antifúngicos (anfotericiana B, fluconazol, nistatina e o extrato de I. suffruticosa). Foram coletadas 68 amostras clínicas em pacientes que apresentavam tumores bucais. Ocorreu o predomínio do gênero masculino, da tumoração na língua e do tipo histológico Carcinoma escamocelular. Um paciente apresentou paracoccidioidomicose que simulava clinicamente lesões neoplásicas. Das amostras clínicas obtidas em tumores bucais, foram isoladas 14 espécies de leveduras, sendo Candida albicans (7), C. famata (2), C. tropicalis (3), C. lusitanie (1), C. parapsilosis (1). Destas apenas os isolados C. famata (7085) e C. tropicalis (7090) não formaram tubo germinativo. Todos os isolados foram capazes de aderir às células epiteliais orais, sendo que 57% apresentaram forte aderência, 14% moderada e 29% fraca aderência. C. famata (7085), C. tropicalis (7092) e C. albicans (7098) não apresentaram atividade proteásica. Com relação ao teste de susceptibilidade a antifúngicos, todas as leveduras foram sensíveis às drogas nistatina e anfotericina B. Os isolados C. albicans (7094) e C. famata (7096) apresentaram resistência ao fluconazol. A proteína inibe o crescimento de C. albicans, C. krusei, C. parapsilosis e C. tropicalis com CIM de 64, 32, 8 e 16 μg.mL⁻¹, respectivamente. Leveduras isoladas em tumores bucais apresentam perfis diversos quanto a patogenicidade e susceptibilidade a drogas antifúngicas. Anfotericina B, nistatina e fluconazol podem ser utilizadas no tratamento de infecções fúngicas da mucosa oral ou sistêmicas em pacientes com câncer de boca. Contudo, se faz importante o diagnóstico micológico em pacientes com suspeita de câncer oral, devido ao perfil clínico que pode simular o câncer e as de infecções associadas.
Malignant oral neoplasm develops from the epithelial lining of the mucosa of the mouth. According to the World Health Organization, there are 640,000 cases of oral cancer, the sixth type being more accessible and responsible for 10% of all malignancies in the world. Several factors are involved in carcinogenesis, including microorganism infections. Yeasts can initiate cancer mechanisms by metabolizing carcinogens, such as nitrosamines. Fungal infections in patients with oral cancer are induced by immunological imbalance due to antineoplastic therapy, as by virulence of the etiological agent. The virulence of Candida species can be determined by the ability of adhesion, proliferation, production of enzymes such as protease, formation of germ tubes and resistance to antifungal drugs, which makes it important to search for new therapeutic alternatives, such as the Indigoffera suffruticosa. The objective of this work is to study the relationship of nitrosamine production, to test the in vitro antifungal susceptibility of conventional drugs and I. suffruticosa extract in yeast isolated from oral malignant neoplasia. Samples were isolated from oral malignant lesions by biopsy, then processed for direct examination and culture. The isolated yeasts were purified and later identified through classical taxonomy and automation. Afterwards, yeast virulence factors were verified for germ tube production, adhesion to oral epithelial cells, protease detection and antifungal sensitivity (amphotericin B, fluconazole, nystatin and I. suffruticosa extract). A total of 68 clinical samples were collected in patients with oral tumors. The predominance of the male gender, of the tumor in the tongue and of the histological type squamous cellular Carcinoma. One patient had paracoccidioidomycosis that clinically mimicked neoplastic lesions. From the clinical samples obtained in oral tumors, 14 yeast species were isolated, being Candida albicans (7), C. famata (2), C. tropicalis (3), C. lusitanie (1) and C. parapsilosis (1). Of these, only C. famata (7085) and C. tropicalis (7090) isolates did not form germ tubes. All isolates were able to adhere to oral epithelial cells, with 57% showing strong adhesion, 14% moderate and 29% poor adherence. C. famata (7085), C. tropicalis (7092) and C. albicans (7098) showed no protease activity. Regarding the antifungal susceptibility test, all yeasts were sensitive to the drugs nystatin and amphotericin B. Isolates C. albicans (7094) and C. famata (7096) showed resistance to fluconazole. The protein inhibits the growth of C. albicans, C. krusei, C. parapsilosis and C. tropicalis with CIM of 64, 32, 8 and 16 μg.mL⁻¹, respectively. Yeasts isolated from oral tumors have different profiles regarding pathogenicity and susceptibility to antifungal drugs. Amphotericin B, nystatin and fluconazole may be used in the treatment of fungal infections of the oral or systemic mucosa in patients with oral cancer. However, the mycological diagnosis is important in patients with suspected oral cancer, due to the clinical profile that can simulate the cancer and the associated infections.
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CAMPOS, Janaina Karin de Lima. "Avaliação da atividade anti-inflamatória, antinociceptiva, antipirética e antioxidante de substâncias isoladas de sementes de Indigofera suffruticosa Mill". Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/26881.
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FACEPE
Conhecida popularmente como “anil” ou “anileira, a Indigofera suffruticosa, é empregada na medicina popular para tratamento de processos inflamatórios e infeccioso, porém poucos estudos foram realizados com o objetivo de estabelecer suas possíveis atividades farmacológicas. Com isto, o presente estudo avaliou as possíveis ações antinociceptiva, anti-inflamatória, antipirética, antidiarréica e antioxidante de extratos orgânicos das vagens secas de I. suffruticosa e ações antinociceptiva, anti-inflamatória, antipirética e antioxidante de uma fração semipurificada de extrato metanólico de vagens secas de I. suffruticosa. Investigações dos metabólitos secundários produzidos por I. suffruticosa foram realizados através do método de cromatografia de camada delgada (CCD). A atividade antinociceptiva foi investigada pelos modelos de contorção abdominal e placa quente. A atividade anti-inflamatória foi avaliada pelos modelos de edema de pata e peritonite (20 e 40 mg/kg, fração). A atividade antidiarreica dos extratos metanólicos (200 e 400 mg/kg) foi investigada através de diferentes metodologias utilizando óleo de Rícino com agente indutor de diarréia. A atividade antipirética do extrato metanólico (200 e 400 mg/kg) foi investigada pelo modelo de Yeast Breath. A atividade antioxidante in vitro dos extratos orgânicos (50 – 500 μg/ml) foi analisado pelo método de DPPH. No modelo de contorções induzidas por ácido acético todos os extratos (éter, clorofórmio, acetona e metanol – 400 mg/kg) apresentaram excelente inibição das contorções quando comparado com o controle. A fração rica em açúcar de I. suffruticosa (20 e 40 mg/kg) também foi capaz de inibir as contorções abdominais. Assim como no modelo de nocicepção de placa quente, apenas os extratos clorofórmio, acetona e metanol (400 mg/kg) se destacaram aumentando o tempo de latência, e também a fração isolada de I. suffruticosa na dose mas elevada, apresentando ação duradoura de até 3 horas. No modelo de edema de pata induzida por carragenina observou-se uma diminuição significativa do edema nos animais tratados com os extratos acetônico e metanólico (dose 400 mg/kg - 60,1 e 58,7%, respectivamente), além também da fração nas doses 20 e 40 mg/kg (70,2 e 73,2%, respectivamente) de I. suffruticosa num período de 5 horas. Na indução da inflamação no modelo de peritonite induzida por carragenina, ambos os extratos (400 mg/kg) promoveram significativamente uma redução na migração leucocitária e também as doses testada da fração (20 e 40 mg/kg) foram capazes de diminuir o acúmulo de neutrófilos na cavidade peritoneal dos camundongos no tempo de 4 horas. No modelo de diarreia induzida em todas as metodologias aplicadas foi possível observar atividade antidiarréica significativa do extrato. Na indução de febre por yeast breath, ambas as doses do extrato metanólico promoveu significativamente a redução da pirexia no animal. Todos os extratos orgânicos testados no modelo de DPPH apresentaram atividade antioxidante (variação de 59,8 – 73 %). O conjunto de resultados sustenta a hipótese popular que a Indigofera suffruticosa possui ações antinociceptivas e anti-inflamatórias, como também atividade antidiarréica, além de contribuir para o acervo científica, destaca também sua potencialidade e utilidade para desenvolvimento de novos fármacos.
Popularly known as "indigo" or "anileira the Indigofera suffruticosa, is used in folk medicine for treating inflammatory and infectious processes, but few studies have been conducted in order to establish the possible pharmacological activities. With this, the present study evaluated the possible antinociceptive actions, anti-inflammatory, antipyretic, antidiarrheal and antioxidant organic extracts of the dried pods of I. suffruticosa and antinociceptive actions, anti-inflammatory, antipyretic and antioxidant of a semipurified fraction of methanol extract of dried pods of I. suffruticosa. Investigations of secondary metabolites produced by I. suffruticosa were performed using the chromatographic method of thin layer (TLC). The antinociceptive activity was investigated by the models of writhing and hot plate. The anti-inflammatory activity was evaluated by the models of peritonitis and paw swelling (20 and 40 mg/kg fraction). The antidiarrheal activity of methanolic extracts (200 and 400 mg/kg) was investigated through different methodologies using Castor oil with diarrhea-inducing agent. The antipyretic activity of the methanol extract (200 and 400 mg/kg) was investigated by the yeast breath model. The in vitro antioxidant activity of organic extracts (50-500 mg/ml) was analyzed by DPPH method. In the writhing model induced by acetic acid extracts all (ether, chloroform, acetone and methanol - 400 mg/kg) showed excellent inhibition of writhings compared with the control. The sugar rich fraction I. suffruticosa (20 and 40 mg / kg) was also able to inhibit writhing. As in the model of nociception hot plate, only the chloroform extracts, acetone and methanol (400 mg/kg) is highlighted by increasing the lag time, and also the isolated fraction I. suffruticosa but at a dose high, with long lasting action to 3 hours. In the carrageenan-induced paw was observed a significant reduction of edema model of edema in animals treated with acetone and methanol extracts (dose 400 mg / kg - 60.1 and 58.7%, respectively), and also in the fraction doses 20 and 40 mg / kg (70.2 and 73.2%, respectively) of I. suffruticosa a period of 5 hours. In the induction of inflammation in the model of peritonitis induced by carrageenan, both extracts (400 mg / kg) significantly promoted a reduction in leukocyte migration and also the doses tested fraction (20 and 40 mg/kg) were able to decrease the accumulation of neutrophils into the peritoneal cavity of mice the time of 4 hours. In diarrhea model induced in all the applied methodologies it observed significant antidiarrheal activity of the extract. In the induction of fever by yeast breath, both doses of the methanol extract significantly promoted the reduction of pyrexia to the animal. All organic extracts tested in the model presented DPPH antioxidant activity (range 59.8 - 73%). The result set supports the popular hypothesis that Indigofera suffruticosa has antinociceptive and anti-inflammatory actions, as well as antidiarrheal activity, and contribute to the scientific collection also highlights its potential and usefulness for development of new drugs.
Libros sobre el tema "Indigofera"
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Thīanklam, ʻAngkhanā. Rāingān wičhai rư̄ang kānkhatlư̄ak phan khrām læ phư̄t thī hai sī khrām: Selection of indigo plant varieties and other plants that give indigo dye. Sakon Nakhon]: Khana Thēknōlōyī Kānkasēt, Mahāwitthayālai Rātchaphat Sakon Nakhō̜n, 2009.
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Tivārī, Rākeśa Kumāra. Unnīsavī śatabdī meṃ nīla saṃskr̥ti kā vikāsa. Naī Dillī, Bhārata: Satyam Pabliśiṅga Hāūsa, 2015.
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Bismarck Plant Materials Center (U.S.). Survivor germplasm false indigo and Silver Sands germplasm sandbar willow. Bismarck, N.D: U.S. Dept. of Agriculture, Natural Resources Conservation Service, Plant Materials Center, 2005.
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Hŏ, Puk-ku. Kŭndae Naju ŭi tchok munhwa wa tchongmul yŏmsaek. Sŏul-si: P'ŏbŭ P'ŭllaen, 2011.
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Gillett, J. B. Indigofera (Microcharis) in Tropical Africa. Kew Publishing, 1989.
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S, Sarada y Reghunath B. R. Evaluation of Indigofera tinctoria L. for yield and glycoside content: Under open and shaded conditions. LAP Lambert Academic Publishing, 2013.
Buscar texto completoCapítulos de libros sobre el tema "Indigofera"
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Evans, P. K. "Indigofera spp." En Biotechnology in Agriculture and Forestry, 645–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74448-8_30.
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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Indigofera glandulosa". En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 582. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_1896.
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Bährle-Rapp, Marina. "Indigofera Tinctoria". En Springer Lexikon Kosmetik und Körperpflege, 279. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_5182.
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Khare, C. P. "Indigofera arrecta Hochst." En Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_782.
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Khare, C. P. "Indigofera enneaphylla Linn." En Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_785.
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Khare, C. P. "Indigofera oblongifolia Forsk." En Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_786.
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Khare, C. P. "Indigofera tinctoria Linn." En Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_788.
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Khare, C. P. "Indigofera trifoliata Linn." En Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_789.
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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Indigofera hirsuta L." En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 582. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_1897.
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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Indigofera trifoliate L." En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 582–83. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_1898.
Texto completoActas de conferencias sobre el tema "Indigofera"
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Muzzazinah, Yanti Sulistyana, Nurmiyati y Kristiandi. "Morphology characterization of pollen Indigofera longeracemosa". En THE 3RD INTERNATIONAL CONFERENCE ON SCIENCE, MATHEMATICS, ENVIRONMENT, AND EDUCATION: Flexibility in Research and Innovation on Science, Mathematics, Environment, and education for sustainable development. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0106462.
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Ali, A., M. Tarmizi y D. Febrina. "Fraksi Serat Pelet Silase Pelepah Kelapa Sawit (Elaeis guineensis) dan Indigofera (Indigofera zollingeriana) dengan Komposisi yang Berbeda". En Prosiding Seminar Nasional Teknologi Peternakan dan Veteriner. Pusat Penelitian dan Pengembangan Peternakan, 2017. http://dx.doi.org/10.14334/pros.semnas.tpv-2017-p.650-657.
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Hutasoit, R., Riyadi Riyadi y SP Ginting. "Pengaruh Suhu Perendaman terhadap Pertumbuhan Kecambah Benih Indigofera zollingeriana". En Prosiding Seminar Nasional Teknologi Peternakan dan Veteriner. Pusat Penelitian dan Pengembangan Peternakan, 2017. http://dx.doi.org/10.14334/pros.semnas.tpv-2017-p.533-540.
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"Efektivitas Pemberian Pelet Indigofera terhadap Pertumbuhan dan Kualitas Daging Kambing Boerka". En Teknologi Peternakan dan Veteriner Mendukung Kemandirian Pangan di Era Industri 4.0. Pusat Penelitian dan Pengembangan Peternakan, 2019. http://dx.doi.org/10.14334/pros.semnas.tpv-2019-p.409-415.
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Fariani, Armina, Gatot Muslim y Anggriawan Naidilah Tetra Pratama. "Comparison of Sorghum Straw (Sorghum bicolor (L.) Moench) Digestible Quality With and Without Indigofera (Indigofera sp) By In Vitro Technique". En 6th International Seminar of Animal Nutrition and Feed Science (ISANFS 2021). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/absr.k.220401.003.
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Muzzazinah, Dwika Sarnia Putri, Alysa Nur Chasanah Alam Majid, Nurmiyati y Kristiandi. "Analysis of phytochemical compounds in Indigofera longeracemosa at Magelang, Trisik and Srandakan". En THE 3RD INTERNATIONAL CONFERENCE ON SCIENCE, MATHEMATICS, ENVIRONMENT, AND EDUCATION: Flexibility in Research and Innovation on Science, Mathematics, Environment, and education for sustainable development. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0106468.
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"Pemanfaatan Fosfat Alam, Pupuk Hayati dan Pupuk Organik Terhadap Produktivitas Benih Indigofera zollinggeriana". En Teknologi Peternakan dan Veteriner Mendukung Kemandirian Pangan di Era Industri 4.0. Pusat Penelitian dan Pengembangan Peternakan, 2019. http://dx.doi.org/10.14334/pros.semnas.tpv-2019-p.779-790.
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Purnama, Herry, Nur Hidayati, Dyah S. Safitri y Sofia Rahmawati. "Effect of initial treatment in the preparation of natural indigo dye from Indigofera tinctoria". En GREEN PROCESS, MATERIAL, AND ENERGY: A SUSTAINABLE SOLUTION FOR CLIMATE CHANGE: Proceedings of the 3rd International Conference on Engineering, Technology, and Industrial Application (ICETIA 2016). Author(s), 2017. http://dx.doi.org/10.1063/1.4985467.
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Yuniati, Yuyun, Achmad Qodim Syafaatullah y Mahfud Mahfud. "Optimization using Box Behnken design for ultrasound assisted extraction natural dyes from Indigofera tinctoria L." En THE 3RD FACULTY OF INDUSTRIAL TECHNOLOGY INTERNATIONAL CONGRESS 2021 INTERNATIONAL CONFERENCE: Enriching Engineering Science through Collaboration of Multidisciplinary Fields. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0117477.
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Ramadhan, Rizky, Idat Galih Permana, Anuraga Jayanegara, Muhamad Nasir Rofiq y Dimar Sari Wahyuni. "Supplementation effectivity of cassava and Indigofera zollingeriana leaves extraction on rumen fermentation system of in vitro". En INTERNATIONAL CONFERENCE ON BIOLOGY AND APPLIED SCIENCE (ICOBAS). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5115730.
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