Bibliografías temáticas / Lippia (Genus)

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Literatura académica sobre el tema "Lippia (Genus)"

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Publicado: 4 de junio de 2021
Última modificación: 5 de febrero de 2022

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Artículos de revistas sobre el tema "Lippia (Genus)"

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Viccini, L. F., P. M. O. Pierre, M. M. Praça, D. C. Souza da Costa, E. da Costa Romanel, S. M. de Sousa, P. H. Pereira Peixoto y F. R. Gonçalves Salimena. "Chromosome numbers in the genus Lippia (Verbenaceae)". Plant Systematics and Evolution 256, n.º 1-4 (20 de octubre de 2005): 171–78. http://dx.doi.org/10.1007/s00606-005-0351-3.

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Filho, José G. Sena, Jennifer M. Duringer, Daniel E. A. Uchoa, Haroudo S. Xavier, Jose M. Barbosa Filho y Raimundo Braz Filho. "Distribution of Iridoid Glucosides in Plants from the Genus Lippia (Verbenaceae): An investigation of Lippia alba (Mill.) N.E. Brown". Natural Product Communications 2, n.º 7 (julio de 2007): 1934578X0700200. http://dx.doi.org/10.1177/1934578x0700200701.

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The distribution of iridoid glucosides in plants from the genus Lippia (Verbenaceae) is described. In the present work, three known iridoids (theviridoside, mussaenoside and gardoside) were isolated from the roots of L. alba and were confirmed by NMR (1H and 13C) spectroscopic data. This information was combined with previous work on seven other Lippia species (obtained through a literature review) to give a thorough account of the iridoid glucosides currently found in this genus.
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Santos, Daiane Rodrigues, Lenaldo Muniz Oliveira, Angelica Maria Lucchese, Alexandre De Freitas Espeleta, Jucelho Dantas Da Cruz y Maurício Santana Lordelo. "Insecticidal activity of essential oils of species from the genus Lippia against Nasutitermes corniger (Motschulsky) (Isoptera: Termitidae)". Sociobiology 67, n.º 2 (30 de junio de 2020): 292. http://dx.doi.org/10.13102/sociobiology.v67i2.4992.

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Lippia is one of the main genera in the family Verbenaceae, with 200 species described. Despite its richness in bioactive molecules, with several scientifically proven applications, there is little information on the insecticidal potential of its species. This study aimed to assess the insecticidal potential of essential oils from the species Lippia thymoides (Martius & Schauer); Lippia lasiocalycina (Schauer) and Lippia insignis (Moldenk) against Nasutitermes corniger (Motschulsky) (Isoptera-Termitidae). Insecticidal activity was evaluated by exposure to a contaminated surface, whereby plastic pots were lined with filter paper and imbibed in 1.5 ml of solution containing essential oils (10 µl/ml), with 10 N. corniger specimens per pot. The mortality count was performed at 24 and 48 h. The LC50 was determined by diluting the essential oils to concentrations of 0, 0.625, 1.25, 2.5, 5.0 and 10 µl/ml, which were chemically analyzed by GC-FID and GC-MS. The data indicated high toxicity for the essential oils for the Lippia species tested. The lowest LC50 (0.46 µl/ml) was recorded for L. lasiocalycina. The most common constituents were β-myrcene and (E)-ocimenone in essential oil of L. lasiocalycina, β-myrcene and limonene for L. insignis, and (E)-caryophyllene and caryophyllene oxide for L. thymoides. The results demonstrate the viability of developing biopesticides for N. corniger control.
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Sousa, Saulo M., Giovana A. Torres y Lyderson F. Viccini. "Karyological studies in Brazilian species of Lippia L. (Verbenaceae)". Anais da Academia Brasileira de Ciências 84, n.º 4 (9 de noviembre de 2012): 1029–37. http://dx.doi.org/10.1590/s0001-37652012005000068.

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The genus Lippia (Verbenaceae) comprise around 160 species spread out mainly in South and Central Americas with few African species, some of them with potential medicinal use. Brazil is one the most important centers of diversity with approximately 75% of the species described so far. Innumerous species are endemic and poorly studied especially at a cytological level. Here, chromosomal length, karyomorphology and chromosome asymmetry of twelve Brazilian species of Lippia were evaluated [L. alba (Miller) N.E.Brown, L. diamantinensis Glaz., L. florida Cham., L. hermanioides Cham., L. lacunosa Mart. & Schauer, L. lupulina Cham., L. pohliana Schauer, L. pseudothea (St. Hil) Schauer, L. rosella Moldenke, L. rotundifolia Cham., L. rubella Moldenke and L. sidoides Cham.]. The analysis suggested that the genus has a variable chromosome number (from 2n = 20 to 2n = 56) originated by dysploidy and polyploidy. This is the first description of chromosome morphology for 11 of the 12 Lippia species studied.
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FUNARI, Cristiano S., Letícia de ALMEIDA, Thais G. PASSALACQUA, Isabel MARTINEZ, Daniela L. AMBRÓSIO, Regina Maria B. CICARELLI, Dulce Helena S. SILVA y Márcia A. S. GRAMINHA. "Oleanonic acid from Lippia lupulina (Verbenaceae) shows strong in vitro antileishmanial and antitrypanosomal activity". Acta Amazonica 46, n.º 4 (diciembre de 2016): 411–16. http://dx.doi.org/10.1590/1809-4392201600204.

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ABSTRACT Leishmaniasis and Chagas disease affect millions of people in tropical and subtropical regions. Drugs used currently to treat such diseases often present undesirable side effects and low efficiency. The aim of this work was to identify extracts and isolated compounds from the genus Lippia with leishmanicidal and trypanocidal activity. Fifteen extracts from different plant parts of Lippia species with partially known chemical compositions, four partition fractions, six compounds and a mixture of four interconverting flavanones previously isolated from Lippia salviaefolia and Lippia lupulina were assayed in vitro towards epimastigote forms of Trypanosoma cruzi and promastigote forms of Leishmania amazonensis. The root extract of L. lupulina had potent activity against T. cruzi and L. amazonensis (IC50 of 20.0 and 54.5 µg mL-1, respectively). The triterpenoid oleanonic acid showed the strongest activity against these protozoans (IC50 of 18.5 and 29.9 µM, respectively). Our results indicate that Lippia plants and their derivatives deserve further investigation in the search for new antiprotozoal drugs, particularly for the treatment of leishmaniasis and Chagas disease.
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Siqueira-Lima, Pollyana S., Fabiolla R. S. Passos, Angélica M. Lucchese, Irwin R. A. Menezes, Henrique D. M. Coutinho, Adley A. N. Lima, Gokhan Zengin, Jullyana S. S. Quintans y Lucindo J. Quintans-Júnior. "Central nervous system and analgesic profiles of Lippia genus". Revista Brasileira de Farmacognosia 29, n.º 1 (enero de 2019): 125–35. http://dx.doi.org/10.1016/j.bjp.2018.11.006.

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Oliveira, Ariana Reis Messias Fernandes de, Lenaldo Muniz Oliveira, José Floriano Barea Pastore, Tânia Regina dos Santos Silva y Larissa Correa do Bonfim Costa. "AGRONOMIC AND MORPHOLOGICAL CHARACTERIZATION OF LIPPIA (VERBENACEAE) SPECIES NATIVE FROM BRAZILIAN SEMIARID REGION". BRAZILIAN JOURNAL OF AGRICULTURE - Revista de Agricultura 92, n.º 2 (8 de agosto de 2017): 147. http://dx.doi.org/10.37856/bja.v92i2.3189.

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The genus Lippia L. is represented by several aromatic species, producing essential oils with biological activity, especially antimicrobial. The semiarid region of Bahia contains several Lippia species that could be economically exploited. This study aimed to characterize morphological and agronomic traits of four species of Lippia native of the semiarid region. The species were collected in a number of cities of the state of Bahia. The experimental design was performed in randomized blocks with four repetitions and four plants per repetition for each species. We conducted quantitative and qualitative morphological characterizations, and evaluated the characters of stem, leaf and inflorescence; in addition to the agronomic characterization, with the fresh and dry matter of inflorescences, we evaluated leaves and stem and essential oil content and yield. The results showed morphological differences between the species for all traits evaluated, except for the number of flowers per inflorescence. The agronomical characterization showed differences for all measured characters, and the species Lippia lasiocalycina was distinguished by the essential oil yield.
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Santos, C. P., D. S. Rocha, M. M. Bajay, F. R. C. Santos, J. B. Campos, J. B. Pinheiro, M. I. Zucchi, R. Silva-Mann, M. F. Arrigoni-Blank y A. F. Blank. "Cross-species transferability of microsatellite markers in the genus Lippia". Genetics and Molecular Research 13, n.º 4 (2014): 9846–50. http://dx.doi.org/10.4238/2014.november.27.11.

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de Campos, José Marcello Salabert, Saulo Marçal Sousa, Pâmela Souza Silva, Lucas Cézar Pinheiro, Fernanda Sampaio y Lyderson Facio Viccini. "Chromosome numbers and DNA C values in the genus Lippia (Verbenaceae)". Plant Systematics and Evolution 291, n.º 1-2 (11 de noviembre de 2010): 133–40. http://dx.doi.org/10.1007/s00606-010-0370-6.

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Sousa, Saulo M., Patrícia M. O. Pierre, Giovana A. Torres, Lisete C. Davide y Lyderson F. Viccini. "Relationship between pollen morphology and chromosome numbers in Brazilian species of Lippia L. (Verbenaceae)". Anais da Academia Brasileira de Ciências 85, n.º 1 (1 de marzo de 2013): 147–57. http://dx.doi.org/10.1590/s0001-37652013005000010.

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The pollen morphology and exine structure of 17 species of Lippia L. were investigated in this work using light and scanning electron microscopy. Among the species studied, 14 showed tricolporate pollen grains, two had tri- and tetracolporate pollen grains and a single species exhibited, only tetracolporate pollen. The amb ranged from triangular to square, and the shape varied from oblate-spheroidal to prolate-spheroidal. Three different types of exine ornamentation were observed: psilate, scabrate and perforate. In addition to morphological data, we found positive association between the chromosome numbers and size of pollen grains, and also between the length and width of the colpi. The results indicate that the characteristics of pollen grains in Lippia may be used as an additional taxonomic character of the genus.
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Tesis sobre el tema "Lippia (Genus)"

1

Terblanche, Francois Cornelius. "Die karakterisering, benutting en vervaardiging van produkte herwin vanuit Lippia scaberrima Sond". Pretoria : [s.n.], 2000. http://upetd.up.ac.za/thesis/available/etd-09062001-100658.

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Mpati, Kwena Winnie. "Response of fever tea (Lippia Javanica) to fertigation frequency, growth medium and propagation method". Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-02202007-113732.

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Bueno, Neto Cyro. "Expressão gênica diferencial na caracterização de espécies de Lippia /". Jaboticabal, 2014. http://hdl.handle.net/11449/122187.

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Orientador: Sonia Marli Zingaretti
Banca: Janete Apparecida Desidério
Banca: Bianca Waleria Bertoni
Resumo: A utilização de plantas na produção de medicamentos deve estar amparada na correta escolha das plantas de onde serão coletados os metabólitos vegetais, isso é de vital importância, posto que a utilização incorreta de uma espécie como provocar sérios danos a saúde do usuário. Em relação ao gênero Lippia, muitas espécies dentro do gênero, produzem metabolitos secundários de inegável importância farmacológica, no entanto apresentam muitas vezes características morfológicas muito similares o que tem concorrido para a identificação errônea da espécie. Nesse trabalho o objetivo foi utilizar técnicas moleculares (Differential Display - PCR e cDNA-AFLP) para auxiliar a identificação dessas espécies através de marcadores moleculares, também se buscou a identificação dos genes que participam nas vias de produção dos metabolitos secundários majoritários dessas espécies. Os resultados obtidos com o Differential Display não detectaram genes envolvidos com a síntese dos metabólitos, porém foram identificadas sequências de microssatèlites e tranposons que podem ser envolvidas na produção desses compostos. Com o cDNA-AFLP não foi possível separar as espécies em relação aos metabólitos secundários produzidos por ela, o que foi observado é uma grande influência do ambiente, bem como de fatores genéticos na produção desses compostos
Abstract: The use of plants in the production of drugs must be supported in the correct choice of plants from which the plant metabolites will be collected, it is of vital importance, since the misuse of a species can cause serious damage to the user's health. Regarding the genus Lippia, many species within the genus, producing secondary metabolites of undeniable pharmacological importance, however they present very similar morphological characteristics which have contributed to the misidentification of species. In this study the objective was to use molecular techniques (Differential Display - PCR and cDNA-AFLP) to assist in identification of these species using molecular markers, also sought to identify genes involved in production routes of the major secondary metabolites of these species. The results obtained by the Differential Display did not detect genes involved in the synthesis of metabolites, however tranposons and microsatellites sequences were identified that may be involved in the production of these compounds. The cDNA-AFLP could not separate the species in relation to secondary metabolites produced by the plants, what was observed is a great influence of the environment, as well as genetic factors in the production of these compounds
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4

Bueno, Neto Cyro [UNESP]. "Expressão gênica diferencial na caracterização de espécies de Lippia". Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/122187.

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A utilização de plantas na produção de medicamentos deve estar amparada na correta escolha das plantas de onde serão coletados os metabólitos vegetais, isso é de vital importância, posto que a utilização incorreta de uma espécie como provocar sérios danos a saúde do usuário. Em relação ao gênero Lippia, muitas espécies dentro do gênero, produzem metabolitos secundários de inegável importância farmacológica, no entanto apresentam muitas vezes características morfológicas muito similares o que tem concorrido para a identificação errônea da espécie. Nesse trabalho o objetivo foi utilizar técnicas moleculares (Differential Display – PCR e cDNA-AFLP) para auxiliar a identificação dessas espécies através de marcadores moleculares, também se buscou a identificação dos genes que participam nas vias de produção dos metabolitos secundários majoritários dessas espécies. Os resultados obtidos com o Differential Display não detectaram genes envolvidos com a síntese dos metabólitos, porém foram identificadas sequências de microssatèlites e tranposons que podem ser envolvidas na produção desses compostos. Com o cDNA-AFLP não foi possível separar as espécies em relação aos metabólitos secundários produzidos por ela, o que foi observado é uma grande influência do ambiente, bem como de fatores genéticos na produção desses compostos
The use of plants in the production of drugs must be supported in the correct choice of plants from which the plant metabolites will be collected, it is of vital importance, since the misuse of a species can cause serious damage to the user's health. Regarding the genus Lippia, many species within the genus, producing secondary metabolites of undeniable pharmacological importance, however they present very similar morphological characteristics which have contributed to the misidentification of species. In this study the objective was to use molecular techniques (Differential Display - PCR and cDNA-AFLP) to assist in identification of these species using molecular markers, also sought to identify genes involved in production routes of the major secondary metabolites of these species. The results obtained by the Differential Display did not detect genes involved in the synthesis of metabolites, however tranposons and microsatellites sequences were identified that may be involved in the production of these compounds. The cDNA-AFLP could not separate the species in relation to secondary metabolites produced by the plants, what was observed is a great influence of the environment, as well as genetic factors in the production of these compounds
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5

José, Diego Pandeló. "Clonagem e caracterização parcial de dois genes de enzimas da via de terpenos em Lippia alba (MILL) N.E. (Verbenaceae)". Universidade Federal de Juiz de Fora (UFJF), 2009. https://repositorio.ufjf.br/jspui/handle/ufjf/3964.

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CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
O gênero Lippia pertence à família Verbenaceae, inclusa no clado Asteridaee, ordem Lamiales, compreendendo aproximadamente 175 gêneros e 2800 espécies, onde muitos gêneros apresentam plantas com propriedades medicinais e ornamentais. A espécie Lippia alba, originária da América do Sul, também ocorre no Brasil e é uma das mais estudadas do gênero Lippia. Ela floresce durante o ano todo e recebe grande destaque no gênero, devido às suas inúmeras propriedades medicinais. O óleo essencial de Lippia alba é composto basicamente por sesqui e monoterpenos, que são as substâncias responsáveis por suas propriedades medicinais. O objetivo central do presente trabalho foi clonar e analisar a expressão de dois potenciais genes codificadores de terpeno sintases em Lippia alba. Através do alinhamento de genes codificadores de monoterpeno sintases caracterizadas, primers degenerados foram desenhados dentro de regiões conservadas e utilizados para se obter a clonagem de genes codificadores de terpeno sintases em Lippia alba. Dois potenciais genes codificadores de terpeno sintases foram clonados, LaTPS12 e LaTPS23. Após a clonagem, técnicas de RT-PCR semiquantitativo foram empregadas para análises de expressão desses dois genes em diferentes estágios foliares e em três diferentes quimiotipos de Lippia alba. Os resultados mostraram que em folhas situadas no quarto segmento nodal o gene LaTPS12 apresenta maior nível de expressão. A diferença na expressão do gene LaTPS23 foi menos acentuada nos três quimiotipos analisados em relação ao gene LaTPS12, que apresentou uma expressão diferencial. Análises filogenéticas foram realizadas comparando-se as seqüências desses dois genes com outros genes codificadores de terpeno sintases já caracterizadas de diferentes espécies de plantas. De acordo com essas análises, LaTPS12 e LaTPS23 pertencem à classe TPS-b, que é composta principalmente por monoterpeno sintases de angiospermas.
The genus Lippia belongs to Verbenaceae family, Asteridaee, order Lamiales. This family comprises about 175 genus and 2800 species, and many of them have medicals and ornamentals proprierties. Lippia alba is native from South America, and is also found in Brazil and is the most studied species of the genus Lippia. This plant blooms throughout the year and has great importance due to its medicinal properties. The Lippia alba essential oils are composed by sesquiterpenes and monoterpenes conferring its medicinal properties. The aim of this work was to clone and to analize gene expression of putative terpene synthases genes (TPS) in Lippia alba. Alignment of TPS genes was used to design degenerate primers into conserved domains for cloning of these genes in Lippia alba. We have cloned two putative TPS genes, LaTPS12 and LaTPS23. After cloning, semiquantitative RT-PCR was employed to expression analysis of these two genes in different leaf stages and among three different chemotypes of Lippia alba. The result of expression level showed that LaTPS12 occurred at higher level in leaves located in fourth nodal segment and showed a marked differential expression among the chemotypes. The difference of expression of the LaTPS23 was less prominent comparing the three studied chemotypes. We performed a phylogenetic analysis in order to compare the LaTPS12 and LaTPS23 to others TPS genes in different plant species. The results showed that these LaTPS12 and LaTPS23 belong to the class TPS-b, which comprises mainly angiosperms monoterpene synthases genes.
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Meidtner, Karina. "Analysis of lipid metabolism-related candidate genes in swine". kostenfrei, 2008. http://mediatum2.ub.tum.de/node?id=629093.

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Molina, Maria Isabel. "Enzymes and genes involved in biosynthesis of plant lipid polyesters". Diss., Connect to online resource - MSU authorized users, 2008.

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Zhang, Qiuping. "Genetic variants of lipid transport genes, dyslipidaemia and coronary heart disease". Thesis, Queen Mary, University of London, 1997. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1642.

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Coronary heart disease (CHD) is one of the most common causes of death in Western Countries. Genetic factors playa major role in the aetiology of CHD, however, the primary defects responsible for the disease have not been identified in most cases. With the application of recombinant DNA technology, it is possible to analyse the putative aetiological role of candidate genes. The role of the Lipoprotein Lipase (LPL) gene and the Apolipoprotein AI-CIII-AIV gene cluster were examined in German and Chinese controls, dyslipidaemics and arteriopaths (coronary artery disease and/or peripheral artery disease). Analyses of four allelic distributions (HindIlI-RFLP, Ser447_Ter, Asp9-Asn and Asn291_Ser mutations) of the LPL gene in German and Chinese populations with or without arterial disease did not show any significant frequency differences. In the German group, plasma triglycerides and VLDL-triglycerides were lower in subjects possessing the Ser447_Ter mutation (p=0.06 and < 0.05 respectively), this mutation was also significantly less frequent in the highest tertiles for triglycerides (p<0.02) and VLDL(P<0.04). The Ser447_Ter variant was found at lower frequencies in the Chinese lipaemic subjects. In addition, two disease related genetic variants (Asp9-Asn and Asn291 _Ser) in Europeans were not found in the Chinese group (P<0.03). Analyses of four genotypic distributions (the ApoAI PstI, MspI, XmnI RFLPs and the ApoCIII G3175_C variant) of the ApoAI-CIII-AIV gene cluster in German and Chinese populations with or without arterial disease did not show any significant differences. However, significant associations between high triglyceride, VLDL, TGIHDL ratio and the PstI RFLP at the ApoAI gene were shown in the German group (p=O.OOl, p<0.02 and p<0.04). In the Chinese group, the rare alleles of the Apo CIII G3175 -C variant and the Apo AI MspI polymorphic variant were both found more frequently in the upper tertile distributions for apo CIII levels and plasma triglyceride/HDL ratios (p<0.05 and p<0.04 respectively). The frequencies of two disease related RFLPs of the ApoAI gene (detected Pane 2 b with Mspl and Xmnl) and the ApoC1I1 G3175 -C variant were significantly different (p<0.0006, p<0.004 and p<0.003 respectively) between Chinese and German control groups. Out of eighteen French patients with diabetes m., obesity and severe hypertriglyceridaemia, eight subjects were found to possess mutations at the LPL gene locus by direct DNA sequencing. Three of these: Argl92_Ter (C829_ T); Phe351 _Leu (C1308_ G) and Thr361 -Thr (C1338 _ A) had not previously been described. Thr361_ Thr appears to be a common population polymorphism whose allele frequency in normolipidaemic diabetics was found to be 0.120 (162 chromosomes studied). The others are all rare at frequencies of <0.01 and may contribute to the phenotype by impairi~g clearance of plasma triglycerides. In eleven of the most lipaemic Chinese subjects, Thr361_Thr (C1338_A) was observed, additionally, the previously published mutations, Ala261_ Thr and Ser447 -Ter, were also noticed. Finally, a Finnish kindred, with premature coronary heart disease and decreased HDL cholesterol levels, was identified having an ApoAI variant (Lys107 ~~) by Single-Strand Conformation Polymorphisms (SSCP) and direct DNA sequencing. This variant was caused by a 3 bp deletion of nucleotides 1396 through 1398 in exon 4 of the ApoAI gene. Ten family members were heterozygous for this mutation. Mean serum apoAI and apoAII levels in heterozygotes were reduced by 18% and 220/0, and cholesteryl ester transfer protein activity (CETP) was reduced by 25% compared with unaffected family members (both p<0.05) respectively, while the plasma lecithin:cholesterol acyltransferase (LCAT) activity did not show any difference between heterozygotes and unaffected family members. The ability of the isolated apoAI variant to serve as a co-factor for LCAT in vitro did not differ from that of normal apoAI.
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Pandeirada, Ana Raquel Gonçalves. "Association between common lipid metabolism genes polymorphisms and sporadic colorectal adenocarcinoma risk". Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/16151.

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Mestrado em Biomedicina Molecular
Lipids can modulate the risk of developing sporadic colorectal adenocarcinoma (SCA), since alterations into lipid metabolism and transport pathways influence directly cholesterol and lipids absorption by colonic cells and indirectly reactive oxygen species (ROS) synthesis in rectum cells due to lipid accumulation. Lipid metabolism is regulated by several proteins APOA1, APOB, APOC3, APOE, CETP, NPY, PON1 and PPARG that could influence both metabolism and transport processes. Is been reported that several common single-nucleotide polymorphisms (SNPs) in these genes could influence their function and/or expression, changing lipid metabolism balance. Thus, genetic changes in those genes can influence SCA development, once the majority of them were never studied in this disease. Furthermore, there are contradictory results between some studied polymorphisms and SCA risk. Thus, the aim of this study was to explore and describe lipid metabolism-associated genes common polymorphisms (APOA1 -75 G>A; APOB R3500Q; APOC3 C3175G, APOC3 T3206G; APOE Cys112/158Arg; CETP G279A, CETP R451Q; NPY Leu7Pro; PON1 Q192R; PPARG Pro12Ala) status among SCA, and their relationship with SCA risk. Genotyping of common lipid metabolism genes polymorphisms (APOA1 75 G>A; APOB R3500Q; APOC3 C3175G, APOC3 T3206G; APOE Cys112/158Arg; CETP G279A, CETP R451Q; NPY Leu7Pro; PON1 Q192R; PPARG Pro12Ala) were done by PCR-SSP techniques, from formalin-fixed and paraffin-embedded biopsies of 100 healthy individuals and 68 SCA subjects. Mutant genotypes of APOA1 -75AA (32% vs 12%; p=0.001; OR=3.51; 95% CI 1.59-7.72); APOB 3500AA (7% vs 0%; p=0.01); APOC3 3175GG (19% vs 2%; p=0.0002; OR=11.58; 95% CI 2.52-53.22), APOC3 3206GG (19% vs 0%; p<0.0001); CETP 279AA (12% vs 1%; p=0.003; OR=13.20; 95% CI 1.61-108.17), CETP 451AA (16% vs 0%; p<0.0001); NPY 7CC (15% vs 0%; p<0.0001); PPARG 12GG (10% vs 0%; p=0.001); and heterozygote genotype PON1 192AG (56% vs 22%; p<0.0001; OR=4.49; 95% CI 2.298.80) were found associated with SCA prevalence. While, APOE E4/E4 (0% vs 8%; p=0.02) mutant haplotype seemed to have a protective effect on SCA. Moreover, it also been founded differences between APOB 3500GA, APOC3 3206TG, CETP 279AA genotypes and PPARG 12Ala allele prevalence and tissue localization (colon vs rectum). These findings suggest a positive association between most of common lipid metabolism genes polymorphisms studied and SCA prevalence. Dysregulation of APOA1, APOB, APOC3, CETP, NPY, PON1 and PPARG genes could be associated with lower cholesterol plasma levels and increase ROS among colon and rectum mucosa. Furthermore, these results also support the hypothesis that CRC is related with intestinal lipid absorption decrease and secondary bile acids production increase. Moreover, the polymorphisms studied may play an important role as biomarkers to SCA susceptibility.
Os lípidos podem modular o risco de desenvolver Adenocarcinoma Colorectal Esporádico (ACE), uma vez que alterações nas vias do metabolismo e do transporte lipídico podem influenciar diretamente a absorção do colesterol e dos lípidos pelas células do cólon e indiretamente a síntese de espécies reativas de oxigénio (ERO) no reto, devido à acumulação de lípidos. O metabolismo lipídico é regulado por várias proteínas (APOA1, APOB, APOC3, APOE, CETP, NPY, PON1, PPARG) que podem influenciar o metabolismo e o transporte de lípidos. Tem sido reportados nestes genes, vários polimorfismos comuns (SNP) que podem alterar a sua função e/ ou a expressão, causando um desequilíbrio no metabolismo dos lípidos. Estas alterações genéticas podem influenciar o desenvolvimento de ACE, no entanto a maioria dos polimorfismos nunca foram estudados nesta patologia. Além disso, existem resultados contraditórios entre alguns dos polimorfismos e o risco de ACE. Deste modo, o objetivo deste estudo foi explorar e descrever o efeito dos polimorfismos comuns de genes associados ao metabolismo lipídico (APOA1 -75 G>A; APOB R3500Q; APOC3 C3175G, APOC3 T3206G; APOE Cys112/158Arg; CETP G279A, CETP R451Q; NPY Leu7Pro; PON1 Q192R; PPARG Pro12Ala) no ACE e a sua relação com o risco de desenvolver ACE. A genotipagem dos polimorfismos comuns de genes associados ao metabolismo lipídico (APOA1 -75 G>A; APOB R3500Q; APOC3 C3175G, APOC3 T3206G; APOE Cys112/158Arg; CETP G279A, CETP R451Q; NPY Leu7Pro; PON1 Q192R; PPARG Pro12Ala) foi efetuada pela técnica de PCR-SSP, a partir de biópsias incluídas em parafina e fixadas em formol de 100 indivíduos saudáveis e de 68 indivíduos com ACE. Os genótipos mutantes APOA1 -75AA (32% vs 12%; p=0.001; OR=3.51; 95% CI 1.59-7.72); APOB 3500AA (7% vs 0%; p=0.01); APOC3 3175GG (19% vs 2%; p=0.0002; OR=11.58; 95% CI 2.52-53.22), APOC3 3206GG (19% vs 0%; p<0.0001); CETP 279AA (12% vs 1%; p=0.003; OR=13.20; 95% CI 1.61-108.17), CETP 451AA (16% vs 0%; p<0.0001); NPY 7CC (15% vs 0%; p<0.0001); PPARG 12GG (10% vs 0%; p=0.001); e o genótipo heterozigótico PON1 192AG (56% vs 22%; p<0.0001; OR=4.49; 95% CI 2.29-8.80) demonstraram estar associados à prevalência de ACE. Enquanto, o haplótipo mutante APOE E4/E4 (0% vs 8%; p=0.02) mostrou ter um efeito protetor no ACE. Adicionalmente, também foram encontradas diferenças entre a prevalência e a localização tumoral (cólon ou reto) para os genótipos APOB 3500GA, APOC3 3206TG, CETP 279AA e para o alelo PPARG 12Ala. Estes resultados sugerem uma associação positiva entre a maioria dos polimorfismos genéticos comuns estudados envolvidos no metabolismo lipídico e a prevalência de ACE. A desregulação dos genes APOA1, APOB, APOC3, CETP, NPY, PON1, PPARG poderá estar associada com a diminuição dos níveis plasmáticos de colesterol e o aumento de ERO na mucosa do colon e do reto. Para além disso, estes resultados também suportam a hipótese de que o CCR esta relacionado com a diminuição da absorção intestinal e com o aumento da produção de ácidos biliares secundários. Adicionalmente, os polimorfismos estudados podem desempenhar um importante papel como biomarcadores de suscetibilidade para ACE.
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Munroe, Patricia Bernadette. "Analysis of genes involved in glucose and lipid metabolism as candidates for essential hypertension". Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321735.

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Libros sobre el tema "Lippia (Genus)"

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Aston, Stephen, Geraint Davies y Nick Beeching. Mycobacterial infection other than tuberculosis. Editado por Patrick Davey y David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0311.

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Mycobacteria are aerobic bacilli with a lipid-rich cell wall and are widespread both in the environment and in animals. Many species within the genus cause disease in humans, most notably those of the Mycobacterium tuberculosis complex, which cause tuberculosis, and Mycobacterium leprae, the causative agent of leprosy. Several other species, termed non-tuberculous mycobacteria, can cause chronic cutaneous, pulmonary, and disseminated infections. This chapter will briefly review infection with non-tuberculous mycobacteria and Mycobacterium leprae.
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Fire in the Genes- Poly-MVA the Cancer Answer? (A Personal research on Cancer and Palladium Lipoic Complexes). Foundation for the Advancement of Med, 2000.

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Renton, Alan E. y Alison M. Goate. Genetics of Dementia. Editado por Dennis S. Charney, Eric J. Nestler, Pamela Sklar y Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0051.

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The genetic architecture of dementia is polygenic and complex, with risk alleles spanning frequency–effect size space. Despite significant progress, most genes influencing these disorders await discovery. Known risk loci implicate perturbed pathways that coalesce around recurring mechanistic themes, notably the autophagosome-lysosome system, the cytoskeleton, endocytosis, innate immunity, lipid metabolism, mitochondria, and the ubiquitin-proteasome system. Phenotypic and pathophysiological pleiotropy suggests some conditions form continuous clinicopathogenetic disease spectra blurring classical diagnoses. Future large-scale genome sequencing of global populations will significantly elucidate etiopathogenesis and is likely to reframe nosology. Furthermore integrative prospective cohort studies have the potential to revolutionize our understanding of dementia.
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Gifford-Gonzalez, Diane. Pastoralism in sub-Saharan Africa. Editado por Umberto Albarella, Mauro Rizzetto, Hannah Russ, Kim Vickers y Sarah Viner-Daniels. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199686476.013.27.

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African pastoralism is distinctive from that of Southwest Asia, focusing on dairy production with cattle, sheep, and goats. The latter were domesticated in Southwest Asia and introduced, but debate continues on whether indigenous African aurochs contributed genes to African domestic cattle. Pastoralism emerged in what was then a grassy Sahara and shifted south with the mid-Holocene aridification. Zooarchaeology and genetics show the donkey is a mid-Holocene African domesticate, emerging as an aid to pastoral mobility during increasing aridity. Pastoralism is the earliest form of domesticate-based food production in sub-Saharan Africa, with farming emerging millennia later. Human genetics and lipid analysis of Saharan ceramics shows an early reliance on dairying. With the emergence of pastoralism, new economies and social relations emerged that were carried by pastoralists across the whole of Africa.
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Capítulos de libros sobre el tema "Lippia (Genus)"

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Marchant, R. y I. M. Banat. "The Genus Geobacillus and Hydrocarbon Utilization". En Handbook of Hydrocarbon and Lipid Microbiology, 1887–96. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-77587-4_138.

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Gengenbach, Burle, Margaret Egli, Sheila Lutz, David Somers, John Gronwald y Don Wyse. "Maize Acetyl-CoEnzyme a Carboxylase Genes". En Plant Lipid Metabolism, 43–45. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8394-7_12.

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de Boer, Gert-Jan, Martin M. Kater, Alwin R. Wagenaar, Tony Fawcett, Toni R. Slabas, H. John, J. Nijkamp y Antoine R. Stuitje. "Structure of Plant Enoyl-ACP Reductase Genes". En Plant Lipid Metabolism, 467–69. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8394-7_127.

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Bossé, Yohan. "Genes, Exercise, and Lipid Metabolism". En Genetic and Molecular Aspects of Sport Performance, 227–39. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444327335.ch20.

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Parimoo, Satish y Pappas Apostolos. "Skin Stearoyl-CoA Desaturase Genes". En Stearoyl-CoA Desaturase Genes in Lipid Metabolism, 13–25. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7969-7_2.

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Breslow, Jan L. "Isolation and Characterization of the Apolipoprotein Genes". En Drugs Affecting Lipid Metabolism VIII, 121–24. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2459-1_10.

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Staley, J. T. "Cycloclasticus: A Genus of Marine Polycyclic Aromatic Hydrocarbon Degrading Bacteria". En Handbook of Hydrocarbon and Lipid Microbiology, 1781–86. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-77587-4_128.

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Nikolau, Basil J., Xiaojie Xu, Yiji Xia, Joel D. Hansen, Shane Heinen, Tsui-Jung Wen, Massimo Delledonne y Patrick S. Schnable. "Molecular Cloning and Characterization of Genes Involved in Cuticular Wax Biosynthesis". En Plant Lipid Metabolism, 127–30. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8394-7_37.

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Smith, Stephen B. "Functional Development of Stearoyl-CoA Desaturase Gene Expression in Livestock Species". En Stearoyl-CoA Desaturase Genes in Lipid Metabolism, 141–59. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7969-7_12.

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Bernlohr, David A. y M. Daniel Lane. "Early Studies on Role of Stearoyl-CoA Desaturase During Preadipocyte Differentiation". En Stearoyl-CoA Desaturase Genes in Lipid Metabolism, 1–11. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7969-7_1.

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Actas de conferencias sobre el tema "Lippia (Genus)"

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Moiseeva, E. V., L. P. Bobrikova, E. V. Karaseva, A. A. Khudokormov, A. A. Samkov y N. N. Volchenko. "Taxonomic diversity of lipolytic bacteria isolated at oil refineries in Krasnodar that is promising for bio-preparation". En 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.173.

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From the lipid-containing wastes, 20 strains of bacteria were isolated. According to MALDI, their taxonomic identity is established, the 13 most active lipolytic strains are classified as 8 genera, the dominant is the genus Pseudomonas.
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El-fadl, Rihab, Nasser Rizk, Amena Fadel y Abdelrahman El Gamal. "The Profile of Hepatic Gene Expression of Glucose Metabolism in Mice on High Fat Diet". En Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0213.

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Obesity is a growing problem worldwide, and recent data indicated that 20% of the populations would be obese. Obesity arises as a multifactorial disease caused by inherited traits that interact with lifestyle factors such as diet and physical activity. The liver plays an essential role in the gluco-regulation via regulating glucose, lipid and protein metabolism. The process of glucose metabolism is controlled by a range of molecular mechanisms and genes which affect the metabolism of the liver during intake of high fat diet (HFD). The objective of this research is to investigate the profile of hepatic gene expression of glucose metabolism in mice on HFD treated with leptin (5 mg/kg BW Ip injection). Ten wild type CD1 mice fed on HFD is used for this study, where groups are control (vehicle - leptin) and test group (vehicle + leptin). Body weight (BW) was measured, and blood chemistry, insulin and leptin were measured at the end of the experiments. Total RNA was isolated from the liver tissue, and RTPCR profiler array technology was used to evaluate the mRNA expression of 84 essential genes of hepatic glucose metabolism. The data of the BW and blood chemistry are not significantly different between the two groups. Leptin treatment enhanced the metabolic pathways and the candidate genes of the different metabolic pathway; glycogen metabolism such as Gys1, Gys2 and Pygm, pentose phosphate shunt such as Rpia and suppressed the glycolysis such as Aldob, and TCA cycle such as Mdh1b. In conclusion, this study has shown that leptin could affect the profile of the hepatic mouse genes of glucose metabolism in the early stages of HFD to induce obesity
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Liao, H., M. Monaghan, A. Dhundale, C. Rubin y S. Judex. "The expression of lipid metabolism genes in bone are altered by mechanical stimuli". En 2007 IEEE 33rd Annual Northeast Bioengineering Conference. IEEE, 2007. http://dx.doi.org/10.1109/nebc.2007.4413264.

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Li, J., S. Bevans-Fonti, LA Shimoda, GL Semenza y VY Polotsky. "Hypoxia Up-Regulates Genes of Lipid Biosynthesis Via Hypoxia Inducible Factor 1 (HIF-1)." En American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5333.

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Pavlenko, O. S., D. A. Evdokimov, N. S. Sadovskaya, O. N. Mustafayev, R. A. Sidorov y I. V. Goldenkova-Pavlova. "Transcriptome analysis of Euonymus europaeusat different stages of fetal development revealed key lipid metabolism genes". En IX Congress of society physiologists of plants of Russia "Plant physiology is the basis for creating plants of the future". Kazan University Press, 2019. http://dx.doi.org/10.26907/978-5-00130-204-9-2019-330.

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Silva, D. L., B. R. Carvalho, H. C. Ferreira Júnior, H. C. Oliveira, L. F. T. Albino, H. S. Rostagno, J. E. Pettigrew, S. E. F. Guimarães y M. I. Hannas. "Sources and levels of zinc affect the expression of genes involved in broiler lipid metabolism". En 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. The Netherlands: Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_100.

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Abdulnour, Raja-Elie E., Judie A. Howrylak, Tamas Dolinay, Lee Gazourian, Rebecca M. Baron, Laura E. Fredenburgh, Anthony F. Massaro, Augustine M. K. Choi y Bruce D. Levy. "ARDS In Patients With Sepsis Is Associated With Differential Expression Of Specific Lipid Signaling Genes". En American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1337.

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Sadik, Mohamed M., Jerry Shan, David Shreiber y Hao Lin. "Extreme Elongation of Vesicles Under DC Electric Fields". En ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193243.

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Motive . The motivation of the current study is to investigate the response of vesicles to applied electric fields, with potential applications in electroporation-mediated molecular delivery [3]. In this technique, an applied field transiently permeabilizes the cell membrane to gain access to the cytoplasm, and deliver active agents such as genes, RNA, proteins into the cell. Although widely applied in classical and emerging areas such as drug delivery and stem cell research, current electroporation techniques suffer from low efficiency and high cell death [4]. The present work is a step towards understanding the complex fundamental processes involved in electroporation, and possibly improving it via parametric optimization. For this purpose we use vesicular cellular mimics as our model to provide good controllability, and to focus on the dynamics of the lipid membrane. Our preliminary results show extreme elongation of the vesicles under high-strength, short-duration DC pulses. Such deformation may significantly affect electroporation, and hence the efficiency of molecular delivery.
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Al-Qeraiwi, Maha, Manar Al-Rashid, Nasser Rizk, Abdelrahman El Gamal y Amena Fadl. "Hepatic Gene Expression Profile of Lipid Metabolism of Obese Mice after treatment with Anti-obesity Drug". En Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0214.

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Obesity is a global disorder with multifactorial causes. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and causes fatty liver. High fat diet intake (HFD) to mice causes the development of dietinduced obesity (DIO). The study aimed to detect the effects of anti-obesity drugs (sulforaphane; SFN and leptin) on hepatic gene expression of fat metabolism in mice that were fed HFD during an early time of DIO. Twenty wild types (WT) CD1 male mice aged ten weeks were fed a high fat diet. The mice were treated with vehicle; Veh (control group), and SFN, then each group is treated with leptin or saline. Four groups of treatment were: control group (vehicle + saline), Group 2 (vehicle + leptin), group 3 (SFN + saline), and group 4 (SFN + leptin). Body weight and food intake were monitored during the treatment period. Following the treatments of leptin 24 hour, fasting blood samples and liver tissue was collected, and Total RNA was extracted then used to assess the gene expression of 84 genes involved in hepatic fat metabolism using RT-PCR profiler array technique. Leptin treatment upregulated fatty acid betaoxidation (Acsbg2, Acsm4) and fatty acyl-CoA biosynthesis (Acot6, Acsl6), and downregulated is fatty acid transport (Slc27a2). SFN upregulated acylCoA hydrolase (Acot3) and long chain fatty acid activation for lipids synthesis and beta oxidation (Acsl1). Leptin + SFN upregulated fatty acid beta oxidation (Acad11, Acam) and acyl-CoA hydrolase (Acot3, Acot7), and downregulated fatty acid elongation (Acot2). As a result, treatment of both SFN and leptin has more profound effects on ameliorating pathways involved in hepatic lipogenesis and TG accumulation and lipid profile of TG and TC than other types of intervention. We conclude that early intervention of obesity pa could ameliorate the metabolic changes of fat metabolism in liver as observed in WT mice on HFD in response to anti-obesity treatment.
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Wang, J., D. Scholtens, M. Holko, D. Ivancic, O. Lee, H. Hu, RT Chatterton y SA Khan. "Abstract P2-10-30: Expression of lipid metabolism genes in contralateral unaffected breast associated with estrogen receptor status of breast cancer". En Abstracts: Thirty-Fifth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 4‐8, 2012; San Antonio, TX. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/0008-5472.sabcs12-p2-10-30.

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