Bibliografías temáticas / Myo-inositol 1

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Literatura académica sobre el tema "Myo-inositol 1"

Autor: Grafiati
Publicado: 6 de septiembre de 2023
Última modificación: 31 de julio de 2025

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Artículos de revistas sobre el tema "Myo-inositol 1"

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Rodrigues, Marta V., Nuno Borges, Mafalda Henriques, et al. "Bifunctional CTP:Inositol-1-Phosphate Cytidylyltransferase/CDP-Inositol:Inositol-1-Phosphate Transferase, the Key Enzyme for Di-myo-Inositol-Phosphate Synthesis in Several (Hyper)thermophiles." Journal of Bacteriology 189, no. 15 (2007): 5405–12. http://dx.doi.org/10.1128/jb.00465-07.

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ABSTRACT The pathway for the synthesis of di-myo-inositol-phosphate (DIP) was recently elucidated on the basis of the detection of the relevant activities in cell extracts of Archaeoglobus fulgidus and structural characterization of products by nuclear magnetic resonance (NMR) (N. Borges, L. G. Gonçalves, M. V. Rodrigues, F. Siopa, R. Ventura, C. Maycock, P. Lamosa, and H. Santos, J. Bacteriol. 188:8128-8135, 2006). Here, a genomic approach was used to identify the genes involved in the synthesis of DIP. Cloning and expression in Escherichia coli of the putative genes for CTP:l-myo-inositol-1
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Stephens, L. R., R. R. Kay, and R. F. Irvine. "A myo-inositol d-3 hydroxykinase activity in Dictyostelium." Biochemical Journal 272, no. 1 (1990): 201–10. http://dx.doi.org/10.1042/bj2720201.

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A soluble ATP-dependent enzyme which phosphorylates myo-inositol has been characterized in Dictyostelium. The myo-inositol kinase activity was partially purified from amoebae by chromatography on DEAE-Sepharose and phenyl-Sepharose columns. The product of both the partially purified activity and of a crude cytosolic fraction was myo-inositol 3-phosphate. The partially purified preparations of myo-inositol kinase (a) possessed a Km for myo-inositol of 120 microM (in the presence of 5 mM-ATP) and for ATP of 125 microM (in the presence of 1 microM-myo-inositol), (b) did not recognize allo-, epi-,
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Burtle, G. J., and R. T. Lovell. "Lack of Response of Channel Catfish (Ictalurus punctatus) to Dietary Myo-inositol." Canadian Journal of Fisheries and Aquatic Sciences 46, no. 2 (1989): 218–22. http://dx.doi.org/10.1139/f89-030.

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Channel catfish (Ictalurus punctatus) fingerlings were fed for 28 wk in aquaria (28 ± 1 °C) on semipurified diets with supplemental myo-inositol (400 mg∙kg diet−1), without myo-inositol, and without myo-inositol but with succinylsulfathiazole to suppress intestinal bacteria synthesis. Omission of myo-inositol from the diet, with or without the antibiotic, did not reduce growth rate, produce overt signs of myo-inositol deficiency, or cause a decrease in tissue (muscle, liver, and brain) concentration of myo-inositol. No lipid accumulation occurred in liver or kidney when myoinositol was deleted
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Stephens, L. R., P. T. Hawkins, A. F. Stanley, et al. "myo-inositol pentakisphosphates. Structure, biological occurrence and phosphorylation to myo-inositol hexakisphosphate." Biochemical Journal 275, no. 2 (1991): 485–99. http://dx.doi.org/10.1042/bj2750485.

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1. Standard and high-performance anion-exchange-chromatographic techniques have been used to purify myo-[3H]inositol pentakisphosphates from various myo-[3H]inositol-prelabelled cells. Slime mould (Dictyostelium discoideum) contained 8 microM-myo-[3H]inositol 1,3,4,5,6-pentakisphosphate, 16 microM-myo-[3H]inositol 1,2,3,4,6-pentakisphosphate and 36 microM-D-myo-[3H]inositol 1,2,4,5,6-pentakisphosphate [calculated intracellular concentrations; Stephens & Irvine (1990) Nature (London) 346, 580-583]; germinating mung-bean (Phaseolus aureus) seedlings contained both D- and L-myo-[3H]inositol 1
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Offer, J., J. C. Metcalfe, and G. A. Smith. "The uptake of 3H-labelled monodeoxyfluoro-myo-inositols into thymocytes and their incorporation into phospholipid in permeabilized cells." Biochemical Journal 291, no. 2 (1993): 553–60. http://dx.doi.org/10.1042/bj2910553.

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Monodeoxyfluoro-myo-inositols were applied to electropermeabilized and intact thymocyte preparations to study their metabolism and uptake in order to investigate their suitability as potential inhibitors of phosphoinositide-mediated cellular responses. Only three of the monodeoxyfluoro-myo-inositols were incorporated into the phospholipids of thymocytes: 1D-3-deoxy-3-fluoro-myo-inositol, 5-deoxy-5-fluoro-myo-inositol and 1D-6-deoxy-6-fluoro-myo-inositol, all of which were weaker substrates for phosphatidylinositol synthase than was myo-inositol. The 3-, 5- and 6-fluoro analogues also behaved a
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Lamosa, Pedro, Lu�s G. Gon�alves, Marta V. Rodrigues, L�gia O. Martins, Neil D. H. Raven, and Helena Santos. "Occurrence of 1-Glyceryl-1-myo-Inosityl Phosphate in Hyperthermophiles." Applied and Environmental Microbiology 72, no. 9 (2006): 6169–73. http://dx.doi.org/10.1128/aem.00852-06.

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ABSTRACT The accumulation of compatible solutes was studied in the hyperthermophilic bacterium Aquifex pyrophilus as a function of the temperature and the NaCl concentration of the growth medium. Nuclear magnetic resonance analysis of cell extracts revealed the presence of α- and β-glutamate, di-mannosyl-di-myo-inositol phosphate, di-myo-inositol phosphate, and an additional compound here identified as 1-glyceryl-1-myo-inosityl phosphate. All solutes accumulated by A. pyrophilus are negatively charged at physiological pH. The intracellular levels of di-myo-inositol phosphate increased in respo
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Biffen, M., and D. E. Hanke. "Reduction in the level of intracellular myo-inositol in cultured soybean (Glycine max) cells inhibits cell division." Biochemical Journal 265, no. 3 (1990): 809–14. http://dx.doi.org/10.1042/bj2650809.

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Although myo-inositol is included in media for the successful growth of plant tissues, the actual requirement of most tissues, including soybean (Glycine max) callus in suspension culture, for myo-inositol has not been demonstrated. We have made use of deoxyglucose to reduce intracellular levels of myo-inositol. Deoxyglucose is phosphorylated to deoxyglucose 6-phosphate, which inhibits L-myo-inositol 1-phosphate synthase, an important enzyme in the synthesis of myo-inositol. Addition of deoxyglucose to the medium resulted in a decrease in the intracellular level of myo-inositol that correspond
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SIU, TEVA, and GREGORY A. AHEARN. "Inositol Transport by Hepatopancreatic Brush-Border Membrane Vesicles of the Lobster Homarus Americanus." Journal of Experimental Biology 140, no. 1 (1988): 107–21. http://dx.doi.org/10.1242/jeb.140.1.107.

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The mechanism of [3H]myo-inositol transport by the lobster hepatopancreas was examined using purified brush-border membrane vesicles. Transport was stimulated by a 100 mmoll−1 inward Na+ gradient, but other cation gradients were ineffective, suggesting a Na+-dependent transfer mechanism. The transport system was most efficient at pH7.0 (both sides), rather than in the presence of a pH gradient (pHin = 7.0; pHout = 5.5) or at bilaterally low pH (pHin = pHout = 5.5). The system was shown to be electrogenic in two different ways. First, myo-inositol uptake was stimulated by anions of increasing p
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Martin, K. L., and T. K. Smith. "The myo-inositol-1-phosphate synthase gene is essential in Trypanosoma brucei." Biochemical Society Transactions 33, no. 5 (2005): 983–85. http://dx.doi.org/10.1042/bst0330983.

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The de novo synthesis of myo-inositol occurs via a two-step process: first, glucose 6-phosphate is converted into inositol 1-phosphate by an INO1 (myo-inositol-1-phosphate synthase; EC 5.5.1.4); then, it is dephosphorylated by an inositol monophosphatase. The myo-inositol can then be incorporated into PI (phosphatidylinositol), which is utilized in a variety of cellular functions, including the biosynthesis of GPI (glycosylphosphatidylinositol) anchors. A putative INO1 was identified in the Trypanosoma brucei genome database and, by recombinant expression in Escherichia coli, was shown to be a
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Borges, Nuno, Luís G. Gonçalves, Marta V. Rodrigues, et al. "Biosynthetic Pathways of Inositol and Glycerol Phosphodiesters Used by the Hyperthermophile Archaeoglobus fulgidus in Stress Adaptation." Journal of Bacteriology 188, no. 23 (2006): 8128–35. http://dx.doi.org/10.1128/jb.01129-06.

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ABSTRACT Archaeoglobus fulgidus accumulates di-myo-inositol phosphate (DIP) and diglycerol phosphate (DGP) in response to heat and osmotic stresses, respectively, and the level of glycero-phospho-myo-inositol (GPI) increases primarily when the two stresses are combined. In this work, the pathways for the biosynthesis of these three compatible solutes were established based on the detection of the relevant enzymatic activities and characterization of the intermediate metabolites by nuclear magnetic resonance analysis. The synthesis of DIP proceeds from glucose-6-phosphate via four steps: (i) gl
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Tesis sobre el tema "Myo-inositol 1"

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Dai, Zhijie, and 戴志洁. "The role of sodium/myo-inositol cotransporter 1 and myo-inositol in osteogenesis and bone formation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43783533.

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Dai, Zhijie. "The role of sodium/myo-inositol cotransporter 1 and myo-inositol in osteogenesis and bone formation." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43783533.

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Chau, Fung-ling Jenny. "Developmental and physiological consequences of sodium/myo-inositol co-transporter 1 deficiency." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B3549606X.

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Ananieva-Stoyanova, Elitsa Antonova. "Identification and Functional Role of Myo-Inositol Polyphosphate 5-Phosphatase Protein Complexes." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/28028.

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To survive, an organism must constantly adjust its internal state to changes in the environment from which it receives signals. The signals set off a chain of events referred to signal transduction. Signal transduction systems are especially important in multicellular organisms, such as plants and animals, because of the need to coordinate the activities of hundreds to trillions of cells. Plants, in particular, have a special need for perceiving signals from their environment because of their static nature. As in the animal cell, the first steps in perception of a signal include signal interac
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Le, Calvez Pierre-Benoit. "Synthesis of novel multisubstrate adducts : putative inhibitors of myo-inositol 1-phosphate synthase." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527923.

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Alves, Karla Shangela da Silva. "Estudo dos nÃveis salivares de mioinositol e quiroinositol em crianÃas saudÃveis e portadores de diabetes infanto- juvenil." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7224.

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CoordenaÃÃo de AperfeiÃoamento de NÃvel Superior<br>A Diabetes mellitus à uma doenÃa de causa mÃltipla, ocorrendo quando hà falta de insulina ou quando a mesma nÃo atua de forma eficaz, causando um aumento da taxa de glicose no sangue (hiperglicemia). Ainda nÃo se sabe precisamente o mecanismo de aÃÃo da insulina, alguns trabalhos sugerem que pode ser possivelmente mediado atravÃs do fosfoglicano inositol (IPGs), cujas algumas formas foram identificadas como: mioinositol e D-quiroinositol. Hà estudos que relacionam a reduÃÃo da glicemia em indivÃduos diabÃticos com o aparecimento desses inosit
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Sayer, Lloyd. "A novel approach towards the stereoselective synthesis of inositols and its application in the synthesis of biologically important molecules." Thesis, University of St Andrews, 2016. http://hdl.handle.net/10023/15658.

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Myo-inositol is ubiquitous in nature and is found at the structural core of a diverse range of biologically important derivatives, including phosphatidylinositols, inositol phosphates and mycothiol. The synthesis of myo-inositol derivatives is notoriously difficult due to the need to control both regio- and enantioselectivity. As a result, synthetic routes to derivatives of this type are often lengthy and low yielding. The first biosynthetic step in the production of all myo-inositol metabolites is the isomerisation of D-glucose 6- phosphate to L-myo-inositol 1-phosphate as mediated by L-myo-i
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Chopera, Denis Rutendo. "Molecular characterization of XvlNO1, a myo-inositol 1-phosphate synthase gene from Xerophyta viscosa." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/4249.

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Includes bibliographical references.<br>Myo-inositol I-phosphate synthase (INO 1) catalyses the conversion of glucose-6-phosphate to myo-inositol I-phosphate, which is subsequently dephosphorylated to myo-inositol. Myo-inositol is a precursor for a number of important metabolites that include membrane components, storage molecules, phytohormones and a variety of osmoprotectants. Xerophyta viscosa Baker (Family Velloziaceae) is a monocotyledonous angiosperm which has the ability to resume full physiological function after desiccation. The full-length cDNA for INO1 from X viscosa was isolated us
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Duthu, Brigitte. "Phosphoranylation de polyols : nouvelle voie d'acces aux myo-inositol phosphates." Toulouse 3, 1988. http://www.theses.fr/1988TOU30129.

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Un procede original de syntheses de myo-inositol phosphates a ete mis au point permettant d'obtenir en une seule preparation plusieurs myo-inositol phosphates a la fois. On fait reagir le myo-inositol avec un dioxa-2,8 aza-5 phospha-1 bicyclo(3. 3. 0) octane. Quand la phosphoranylation est totale on obtient les myo-inositol mono, bis, tris, tetrakis phosphates
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Hegeman, Carla Elizabeth. "Isolation and Characterization of Soybean Genes Involved in Phytic Acid Metabolism: Phytase and 1-L-myo-Inositol-1-Phosphate Synthase." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/29906.

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The objective of this research was to isolate and characterize soybean genes involved in phytic acid metabolism for use in genetic engineering strategies to improve phosphorus utilization. A soybean phytase from germinated cotyledons was purified 28,000-fold to apparent homogeneity and was determined to be a glycosylated homodimer with 70 kD subunits. Soybean phytase preferred phytate as substrate (Km = 60 mM) and was capable of removing of all six phosphate groups from phytate. The pH and temperature optima for soybean phytase activity were 4.5 and 58*C, respectively. The N-terminus and fo
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Libros sobre el tema "Myo-inositol 1"

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Biswas, B. B., and Susweta Biswas, eds. myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5.

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Healy, Christopher. Synthetic studies on the inhibition of L-myo-inositol 1-phosphate synthase. University of Birmingham, 1991.

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Tan, Chui Heong. Synthetic studies on the inhibition of L-myo-inositol-1-phosphate synthase. University of Birmingham, 1994.

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Capítulos de libros sobre el tema "Myo-inositol 1"

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Schomburg, Dietmar, and Dörte Stephan. "myo-Inositol 1-kinase." In Enzyme Handbook 13. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-59176-1_174.

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Schomburg, Dietmar, and Dörte Stephan. "myo-Inositol 1-O-methyltransferase." In Enzyme Handbook 11. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61030-1_37.

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Schomburg, Dietmar, and Margit Salzmann. "1L-Myo-inositol-1-phosphatase." In Enzyme Handbook 3. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76463-9_86.

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Schomburg, Dietmar, and Dörte Stephan. "1D-myo-Inositol-tetrakisphosphate 1-kinase." In Enzyme Handbook. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-59025-2_29.

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Murthy, Pushpalatha P. N. "Inositol Phosphates and Their Metabolism in Plants." In myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5_8.

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Raboy, Victor, and Paolo Gerbasi. "Genetics of myo-Inositol Phosphate Synthesis and Accumulation." In myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5_9.

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Sopory, Sudhir K., and Meena R. Chandok. "Light-Induced Signal Transduction Pathway Involving Inositol Phosphates." In myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5_12.

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Schultz, Carsten, Anne Burmester, and Christoph Stadler. "Synthesis, Separation, and Identification of Different Inositol Phosphates." In myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5_13.

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Hokin, Lowell E. "History of Phosphoinositide Research." In myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5_1.

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Biswas, Susweta, and B. B. Biswas. "Metabolism of myo-Inositol Phosphates and the Alternative Pathway in Generation of myo-Inositol Trisphosphate Involved in Calcium Mobilization in Plants." In myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0343-5_10.

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Actas de conferencias sobre el tema "Myo-inositol 1"

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Sajja, Sujith, Shane A. Perrine, Farhad Ghoddoussi, Matthew P. Galloway, and Pamela J. VandeVord. "Increased Levels of Myo-Inositol are Associated With Impaired Working Memory and Active Avoidance in Blast Neurotrauma Animals." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80466.

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Impaired working memory and anxiety are major clinical symptoms commonly associated with subjects exposed to blast overpressure [1–4]. Despite this association, there remains a vital need for biomarkers to help effectively diagnosis blast-induced neurotrauma (BINT). Clinically, elevated myo-inositol has been associated with several neurodegenerative disorders including dementia and elevated levels may reflect activation of microglia. In the present study, we evaluated the cognitive and behavioral changes in blast exposed animals using the novel object recognition (working memory paradigm) and
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Medini, L., P. Maderna, E. Tremoli, and C. Galli. "PLATELETS FROM TYPE IIA HYPERCHOLESTEROLEMIC PATIENTS GENERATE MORE INOSITOLPHOSPHATES AFTER THROMBIN STIMULATION IN COMPARISON WITH THOSE OF NORMAL SUBJECTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643415.

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Functional and biochemical responses of platelets to stimulating agents have been reported to be amplified in several pathological conditions, including hyperlipidemia. Enhanced aggregation and thromboxane formation are, e.g. frequently observed in the presence of high plasma cholesterol levels (type Ila hypercholesterolemia). Stimulation of phosphoinositides breakdown through specific phosphohydrolases (phospholipase C) resulting in the formation of inositolphosphates (IPs), is one of the early events in platelet activation. A study was thus designed in order to investigate IPs generation in
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Novais, Aurea Maria Lago, and Renan Carvalho Castello Branco. "Mechanisms of Neuroplasticity After Pediatric Stroke: A Review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.241.

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Introduction: Stroke in childhood constitute a rare event and its incidence is increasing due to advances in neuroimaging.This study clarifies anatomic and molecular mechanisms involved in neuroplasticity after children stroke, demonstrating its specificities in motor,somatosensory and language habilities. Methods: We used database, from 2000 to march 2021,of SpringerLink,NEJM,PubMed, AHA (Stroke),Scielo,VHL and JAMA.The research was based in the keywords “neuplasticity”, “stroke” and “children”; 57 were selected including original articles, case reports and reviews, considering abstract accor
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