Bibliografías temáticas / Oligomers

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Literatura académica sobre el tema "Oligomers"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 25 de julio de 2025

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Artículos de revistas sobre el tema "Oligomers"

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Lucas, Lathan, Phoebe S. Tsoi, Josephine C. Ferreon, and Allan Chris M. Ferreon. "Tau Oligomers Resist Phase Separation." Biomolecules 15, no. 3 (2025): 336. https://doi.org/10.3390/biom15030336.

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Tau is a microtubule-associated protein that undergoes liquid–liquid phase separation (LLPS) to form condensates under physiological conditions, facilitating microtubule stabilization and intracellular transport. LLPS has also been implicated in pathological Tau aggregation, which contributes to tauopathies such as Alzheimer’s disease. While LLPS is known to promote Tau aggregation, the relationship between Tau’s structural states and its phase separation behavior remains poorly defined. Here, we examine how oligomerization modulates Tau LLPS and uncover key distinctions between monomeric, oli
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Vaikath, Nishant, Indulekha Sudhakaran, Ilham Abdi, et al. "Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers." International Journal of Molecular Sciences 23, no. 23 (2022): 14630. http://dx.doi.org/10.3390/ijms232314630.

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The aggregation of α-synuclein (α-syn) into neurotoxic oligomers and fibrils is an important pathogenic feature of synucleinopatheis, including Parkinson’s disease (PD). A further characteristic of PD is the oxidative stress that results in the formation of aldehydes by lipid peroxidation. It has been reported that the brains of deceased patients with PD contain high levels of protein oligomers that are cross-linked to these aldehydes. Increasing evidence also suggests that prefibrillar oligomeric species are more toxic than the mature amyloid fibrils. However, due to the heterogenous and meta
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Grewal, Annu, Deepak Sheokand, Vandana Saini та Ajit Kumar. "Molecular docking analysis of α-Synuclein aggregation with Anle138b". Bioinformation 20, № 3 (2024): 217–22. http://dx.doi.org/10.6026/973206300200217.

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α-Synuclein aggregation into toxic oligomeric species is central to Parkinson痴 disease pathogenesis. Anle138b is a recently identified inhibitor of α-synuclein oligomerization showing promise in preclinical studies. This study employed computational approaches to elucidate Anle138b痴 mechanism of oligomer-specific action. The inhibitory potential of Anle138b against α-synuclein oligomers was evaluated by performing molecular docking studies using AutoDock Tools, followed by their binding pocket analysis. Further, protein-protein docking studies were performed using Hex8.0 to validate the aggreg
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Wang, Yu, Karen S. L. Lam, Ming-hon Yau, and Aimin Xu. "Post-translational modifications of adiponectin: mechanisms and functional implications." Biochemical Journal 409, no. 3 (2008): 623–33. http://dx.doi.org/10.1042/bj20071492.

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Adiponectin is an insulin-sensitizing adipokine with anti-diabetic, anti-atherogenic, anti-inflammatory and cardioprotective properties. This adipokine is secreted from adipocytes into the circulation as three oligomeric isoforms, including trimeric, hexameric and the HMW (high-molecular-mass) oligomeric complex consisting of at least 18 protomers. Each oligomeric isoform of adiponectin exerts distinct biological properties in its various target tissues. The HMW oligomer is the major active form mediating the insulin-sensitizing effects of adiponectin, whereas the central actions of this adipo
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Liu, Guang-Hui, Jing Qu, Anne E. Carmack, et al. "Lipin proteins form homo- and hetero-oligomers." Biochemical Journal 432, no. 1 (2010): 65–76. http://dx.doi.org/10.1042/bj20100584.

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Lipin family members (lipin 1, 2 and 3) are bi-functional proteins that dephosphorylate PA (phosphatidic acid) to produce DAG (diacylglycerol) and act in the nucleus to regulate gene expression. Although other components of the triacylglycerol synthesis pathway can form oligomeric complexes, it is unknown whether lipin proteins also exist as oligomers. In the present study, using various approaches, we revealed that lipin 1 formed stable homo-oligomers with itself and hetero-oligomers with lipin 2/3. Both the N- and C-terminal regions of lipin 1 mediate its oligomerization in a head-to-head/ta
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Prots, Iryna, Janina Grosch, Razvan-Marius Brazdis та ін. "α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies". Proceedings of the National Academy of Sciences 115, № 30 (2018): 7813–18. http://dx.doi.org/10.1073/pnas.1713129115.

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α-Synuclein (α-Syn) aggregation, proceeding from oligomers to fibrils, is one central hallmark of neurodegeneration in synucleinopathies. α-Syn oligomers are toxic by triggering neurodegenerative processes in in vitro and in vivo models. However, the precise contribution of α-Syn oligomers to neurite pathology in human neurons and the underlying mechanisms remain unclear. Here, we demonstrate the formation of oligomeric α-Syn intermediates and reduced axonal mitochondrial transport in human neurons derived from induced pluripotent stem cells (iPSC) from a Parkinson’s disease patient carrying a
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Di Gennaro, Patrizia, Valentina Sabatini, Silvia Fallarini, Roberto Pagliarin, and Guido Sello. "Polyphenol Polymerization by an Alternative Oxidative Microbial Enzyme and Characterization of the Biological Activity of Oligomers." BioMed Research International 2018 (2018): 1–10. http://dx.doi.org/10.1155/2018/3828627.

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The recombinant catalase-peroxidase HPI from E. coli was used as an alternative enzyme in polymerization reactions for the production of (−) epicatechin oligomers and their biological activity was characterized. The enzyme was prepared in two forms: a purified and an immobilized form. Both were tested for their activity in oxidative polymerization reactions, and their stability and reusability were assessed. The polymerization reactions were followed by SEC-HPLC analyses, and the substrate was completely converted into one or more polymerization products depending on the reactions conditions.
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Bazaco, Raúl Blanco, José L. Segura, and Carlos Seoane. "Recent advances in the design, synthesis and study of covalent conjugated oligomer–C60 ensembles." Collection of Czechoslovak Chemical Communications 74, no. 6 (2009): 857–86. http://dx.doi.org/10.1135/cccc2008218.

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This review presents an overview of the most recent results in the field of conjugated oligomer covalently attached to the C60 sphere focusing mainly on donor–conjugated oligomer–C60 triads and conjugated oligomer–multifullerene materials. Well-defined monodisperse oligomers as new materials that exhibit interesting optoelectronic properties have been the subject of intense study during the last decade. In this regard, a huge amount of work has been devoted to the development of new synthetic strategies toward the synthesis of conjugated oligomeric materials with precise length and constitutio
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Burford, Neil T., Tom Wehrman, Daniel Bassoni та ін. "Identification of Selective Agonists and Positive Allosteric Modulators for µ- and δ-Opioid Receptors from a Single High-Throughput Screen". Journal of Biomolecular Screening 19, № 9 (2014): 1255–65. http://dx.doi.org/10.1177/1087057114542975.

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Hetero-oligomeric complexes of G protein–coupled receptors (GPCRs) may represent novel therapeutic targets exhibiting different pharmacology and tissue- or cell-specific site of action compared with receptor monomers or homo-oligomers. An ideal tool for validating this concept pharmacologically would be a hetero-oligomer selective ligand. We set out to develop and execute a 1536-well high-throughput screen of over 1 million compounds to detect potential hetero-oligomer selective ligands using a β-arrestin recruitment assay in U2OS cells coexpressing recombinant µ- and δ-opioid receptors. Heter
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Renaud, Justin, Abdulhrahman M. Alhazmi, and Paul M. Mayer. "Comparing the fragmentation chemistry of gas-phase adducts of poly(dimethylsiloxane) oligomers with metal and organic ions." Canadian Journal of Chemistry 87, no. 2 (2009): 453–59. http://dx.doi.org/10.1139/v08-184.

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Gas-phase ions of poly(dimethylsiloxane) oligomers were formed by electrospray ionization either by protonating them in solution with formic acid or by generating adducts of the oligomers with the metal ions Li+, Na+, K+, and Ag+ as well as with the organic cations NH4+, CH3CH2NH3+, and protonated glycine, aspartic acid, and 1,2-diphenylethylamine. The collision-induced fragmentation of the oligomeric ions was strongly dependent on the nature of the charging species. Ag+ adducts dissociated in a manner previously observed in secondary ion mass spectrometry experiments generating a series of li
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Tesis sobre el tema "Oligomers"

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Sun, Xiaohua. "Synthesis and properties of monodisperse oligomer-substituted calix[4]arene assemblies and related oligomers." HKBU Institutional Repository, 2006. http://repository.hkbu.edu.hk/etd_ra/706.

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Cerf, Emilie. "Unraveling Alzheimer's disease: insight into the influence of apolipoprotein E isoforms on Abeta aggregation." Doctoral thesis, Universite Libre de Bruxelles, 2011. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209880.

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Nowadays, the emerging role of amyloid-β peptide (Aβ) oligomers in Alzheimer’s disease (AD) is widely accepted, putting aside the old idea that fibrils are the primary entities responsible for the onset of the disease. Recent studies indeed show that the level of soluble Aβ oligomeric forms better correlates with the progression of the disease than the level of fibrillar forms. <p>Using conditions which yield characteristic Aβ42 oligomers or fibrils, we studied the secondary structure of these species by ATR (attenuated total reflection)-FTIR (Fourier transform infrared) spectroscopy. Whereas
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Lederer, Kay. "Crystalline assemblies of folded oligomers." [S.l. : s.n.], 1999. http://ArchiMeD.uni-mainz.de/pub/2000/0036/diss.pdf.

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Anderson, Sally. "Templated synthesis of porphyrin oligomers." Thesis, University of Cambridge, 1993. https://www.repository.cam.ac.uk/handle/1810/251546.

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Forrest, Martin J. "Characterisation of vinyl chloride oligomers." Thesis, Loughborough University, 1988. https://dspace.lboro.ac.uk/2134/27931.

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A low molecular weight fraction was obtained from a mass polymerised PVC resin by using diethyl ether Soxhlet extraction followed by either preparative gel filtration or solvent fractionation. A gas chromatography - mass spectroscopy (GC-MS) analysis of this fraction revealed that, in addition to vinyl chloride (VC) oligomers, it contained a large number of other compounds, in particular a large concentration of phthalates. By using adsorption liquid chromatography it was possible to remove the phthalates, along with other contaminants having a similar or greater polarity, from the low molecul
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Szczypiński, Filip Tomasz. "Ester-based synthetic information oligomers." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289396.

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Wahl, Markus C. "Crystal Structures of RNA Oligomers /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487933245536475.

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Doss, Raymond Michael Stoltz Brian M. Dervan Peter B. "Programmable oligomers for DNA recognition /." Diss., Pasadena, Calif. : California Institute of Technology, 2006. http://resolver.caltech.edu/CaltechETD:etd-09202008-110622.

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Stross, Alexander. "Synthetic H-bonding information oligomers." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/12365/.

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The nucleic acids contain chemical information in the form of a sequence of bases. This information content is expressed through sequence selective duplex formation and template directed synthesis. To date, the only programmable artificial information molecules that can truly rival the nucleic acids, in terms of their function, are structurally very similar to the nucleic acids. This thesis describes a synthetic approach to duplex forming hydrogen bonding oligomers that contain information in the form of a sequence of H-bond donor and acceptor groups, in the pursuit of a programmable material
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Deloule, Vivien. "Study on extraction and characterization of softwoods hemicelluloses oligomers and their influence on gut microbiota." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAI107.

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Libros sobre el tema "Oligomers"

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Uglea, Constantin V. Synthesis and characterization of oligomers. CRC Press, 1991.

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Uglea, Constantin V. Liquid chromatography of oligomers. M. Dekker, 1996.

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Moulton, Hong M., and Jon D. Moulton, eds. Morpholino Oligomers. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6817-6.

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Harris, Frank W., and Harry J. Spinelli, eds. Reactive Oligomers. American Chemical Society, 1985. http://dx.doi.org/10.1021/bk-1985-0282.

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1942-, Harris Frank Wayne, Spinelli Harry J. 1949-, American Chemical Society. Division of Polymer Chemistry., American Chemical Society. Division of Polymeric Materials: Science and Engineering., and American Chemical Society Meeting, eds. Reactive oligomers. American Chemical Society, 1985.

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Ėntelis, S. G. Reactive oligomers. VSP, 1989.

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A, Shagini͡an Sh, та Institut khimicheskoĭ fiziki im. N.N. Semenova, ред. Spinodalʹnyĭ raspad binarnykh smeseĭ oligomerov v uslovii͡akh khimicheskoĭ reakt͡sii. Tip. IKhFCh RAN, 1994.

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Francqui, Colloquium (4th 1998 Brussels Belgium). Conjugated oligomers, polymers, and dendrimers: From polyacetylene to DNA : proceedings of the Fourth Francqui Colloqium, 21-23 October 1998, Brussels. De Boeck Université, 1999.

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Mezhikovskiĭ, S. M. Fizikokhimii͡a︡ reakt͡s︡ionnosposobnykh oligomerov: Termodinamika, kinetika, struktura. Nauka, 1998.

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A, Krent͡s︡elʹ B., Borisova, N. A., kandidat khimicheskikh nauk. та Institut neftekhimicheskogo sinteza im. A.V. Topchieva., ред. Oligomerizat͡s︡ii͡a︡ nepredelʹnykh uglevodorodov. Akademii͡a︡ nauk SSSR, In-t neftekhimicheskogo sinteza im. A.V. Topchieva, 1987.

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Capítulos de libros sobre el tema "Oligomers"

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Mezhikovskii, Semjon M., P. Pozdeev, and A. V. Vakula. "Oligomers And Characteristics Of Oligomer Blends." In Physico-Chemical Principles for Processing of Oligomeric Blends. CRC Press, 2024. http://dx.doi.org/10.1201/9781003580751-1.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Synthesis of Reactive Oligomers and the Formation of Functionally-Defective Macromolecules." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-3.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Characteristic Features of Gel Permeation Chromatography of Oligomers with RFGs." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-12.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Liquid Chromatography of Functional Oligomers Near Critical Conditions." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-8.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Basic Experimental Regularities of Liquid Chromatography of Oligomers with RFGs." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-6.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Molecular Weight Distribution of Oligomers with RFGs." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-11.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Molecular Heterogeneity of Oligomers." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-15.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Methods for Determining the Average Functionalities." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-4.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "General Regularities of the Chromatography of Macromolecules under Critical and Near Critical Conditions." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-7.

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Entelis, S. G., V. V. Evreinov, A. I. Kuzaev, V. M. Divid, and Yu U. Rajabov. "Liquid Chromatography of Functional Oligomers under Critical Conditions." In Reactive Oligomers. CRC Press, 2023. http://dx.doi.org/10.1201/9780429087561-9.

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Actas de conferencias sobre el tema "Oligomers"

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Johnson, Kevin J., Auston C. Grant, Adam Trupp, et al. "NPLT-induced resilience of neural stem cells against tau oligomers." In Photons Plus Ultrasound: Imaging and Sensing 2025, edited by Alexander A. Oraevsky and Lihong V. Wang. SPIE, 2025. https://doi.org/10.1117/12.3049102.

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Shutikov, A. A., G. M. Arzumanyan, K. Z. Mamatkulov, E. Arynbek та D. S. Zakrytnaya. "ANALYSIS OF THE SECONDARY STRUCTURE OF AΒ (1-42) PEPTIDE IN THE AMIDE I REGION BY RAMAN SPECTROSCOPY". У X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-220.

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Amyloid fibrils found in plaques in Alzheimer’s disease (AD) brains are composed of amyloid-β peptides. Aβ peptides are formed from the transmembrane amyloid precursor protein (APP). They have pronounced fibrillogenic properties, and its oligomers are toxic to nerve cells, causing their degeneration and death. Oligomeric amyloid-β (1-42) is thought to play a critical role in neurodegeneration in AD. In this work, we analyzed the conformational transformation of Aβ (1-42) peptides embedded in membrane mimetics by Raman spectroscopy. The main goal of the scientific study was to investigate the s
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Hentschel, Mario, Martin Schäferling, Thomas Weiss, Hans-Georg Kuball, Na Liu, and Harald W. Giessen. "Three-dimensional Chiral Plasmonic Oligomers." In Quantum Electronics and Laser Science Conference. OSA, 2012. http://dx.doi.org/10.1364/qels.2012.qth4f.1.

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Kim, Y. H., F. Li, and H. Zimmer. "Charged states of thiophene oligomers." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.834786.

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Ozols, Andris O., Valdis Kampars, Mara Reinfelde, and Valdis Kokars. "Hologram recording in azobenzene oligomers." In SPIE Proceedings, edited by Janis Spigulis, Janis Teteris, Maris Ozolinsh, and Andrejs Lusis. SPIE, 2003. http://dx.doi.org/10.1117/12.517010.

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Ding, Y., S. Garland, M. Howland, A. Revzin, and T. Pan. "Universal nano-adhesive of PDMS oligomers." In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2012. http://dx.doi.org/10.1109/memsys.2012.6170210.

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Weber, Thorsten, Felix von Cube, Stephan Irsen, and Stefan Linden. "Near-field Study of Plasmonic Oligomers." In Quantum Electronics and Laser Science Conference. OSA, 2012. http://dx.doi.org/10.1364/qels.2012.qw1b.2.

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Kroychuk, M. K., E. V. Melik-Gaykazyan, A. S. Shorokhov, et al. "Nonlinear anisotropy in silicon nanoparticle oligomers." In ADVANCES IN ELECTRICAL AND ELECTRONIC ENGINEERING: FROM THEORY TO APPLICATIONS: Proceedings of the International Conference on Electrical and Electronic Engineering (IC3E 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.4998096.

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Fritsch, V., and E. Westhof. "Molecular Dynamics Simulations of DNA Oligomers." In Advances in biomolecular simulations. AIP, 1991. http://dx.doi.org/10.1063/1.41351.

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Poplawski, J., E. Ehrenfreund, R. Pugh, et al. "Photogeneration of polarons in sexithiophene oligomers." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.834699.

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Informes sobre el tema "Oligomers"

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Good, J. R., and Aileen Huang-Saad. Nucleotide Oligomers. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada407868.

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Hnatowich, DJ. Targeting Cancer with Antisense Oligomers. Office of Scientific and Technical Information (OSTI), 2008. http://dx.doi.org/10.2172/940005.

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Rajca, Andrzej. Polymers and Oligomers of Carbon-Sulfur Helicenes. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada421423.

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Reynolds, John R. Electroactive Reactive Oligomers and Polymers as Device Components. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada510609.

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Peterson, Rebecca A. Antagonistic Action of Hyaluronan Oligomers in Breast Cancer. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada377165.

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Toole, Bryan P., and Jeanine Ward. Antagonistic Action of Hyaluronan Oligomers in Breast Cancer. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada381536.

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Robert Perry, Teresa Grocela-Rocha, Michael O'Brien, et al. Novel High Capacity Oligomers for Low Cost CO2 Capture. Office of Scientific and Technical Information (OSTI), 2010. http://dx.doi.org/10.2172/1013258.

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Baker, Kenneth N., and Albert V. Fratini. Crystal Structures of Poly-Paraphenylene Oligomers Containing Pendant Phenyl Groups. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada218158.

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Koberstein, Jeffrey T. Molecular Engineering of Thin Polymer Films Prepared from Functionally-Terminated Oligomers. Defense Technical Information Center, 1995. http://dx.doi.org/10.21236/ada291681.

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Garcia, A. E., and G. Hummer. Theoretical studies of the interaction of water with DNA oligomers and proteins. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/212500.

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