Bibliografías temáticas / Receptors

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Literatura académica sobre el tema "Receptors"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 25 de julio de 2025

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Artículos de revistas sobre el tema "Receptors"

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Tibrewal, Richa, Reynoldly Kharsyntiew, Farida Dawood, and Archana Sharma. "A REVIEW ON G-PROTEIN COUPLED RECEPTOR." International Journal of Current Pharmaceutical Review and Research 13, no. 04 (2021): 01–09. https://doi.org/10.5281/zenodo.12664417.

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AbstractG protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domainreceptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linkedreceptors (GPLR), constitute a large protein family of receptors that detect molecules outsidethe cell and activate internal signal transduction pathways and, ultimately, cellular responses.Coupling with G proteins, they are called seven-transmembrane receptors because they passthrough the cell membrane seven times. G protein–coupled receptors are found only ineukaryotes, including yeast, choanof
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Jaremko, William J., Zhen Huang, Wei Wen, Andrew Wu, Nicholas Karl, and Li Niu. "Identification and characterization of RNA aptamers: A long aptamer blocks the AMPA receptor and a short aptamer blocks both AMPA and kainate receptors." Journal of Biological Chemistry 292, no. 18 (2017): 7338–47. http://dx.doi.org/10.1074/jbc.m116.774752.

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AMPA and kainate receptors, along with NMDA receptors, represent different subtypes of glutamate ion channels. AMPA and kainate receptors share a high degree of sequence and structural similarities, and excessive activity of these receptors has been implicated in neurological diseases such as epilepsy. Therefore, blocking detrimental activity of both receptor types could be therapeutically beneficial. Here, we report the use of an in vitro evolution approach involving systematic evolution of ligands by exponential enrichment with a single AMPA receptor target (i.e. GluA1/2R) to isolate RNA apt
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Santiago, Luis, and Ravinder Abrol. "Understanding G Protein Selectivity of Muscarinic Acetylcholine Receptors Using Computational Methods." International Journal of Molecular Sciences 20, no. 21 (2019): 5290. http://dx.doi.org/10.3390/ijms20215290.

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The neurotransmitter molecule acetylcholine is capable of activating five muscarinic acetylcholine receptors, M1 through M5, which belong to the superfamily of G-protein-coupled receptors (GPCRs). These five receptors share high sequence and structure homology; however, the M1, M3, and M5 receptor subtypes signal preferentially through the Gαq/11 subset of G proteins, whereas the M2 and M4 receptor subtypes signal through the Gαi/o subset of G proteins, resulting in very different intracellular signaling cascades and physiological effects. The structural basis for this innate ability of the M1
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Steverding, Dietmar. "Cycle Numbers of Cell Surface Recycling Receptors." Receptors 2, no. 2 (2023): 160–65. http://dx.doi.org/10.3390/receptors2020010.

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The cycle number (nc) of a recycling receptor is defined as the average number of round trips (cell surface–endosome–cell surface) the receptor can make before it is degraded. This characteristic parameter of recycling receptors can be easily determined from the receptor’s half-life (t½, the time in which 50% of the receptor is degraded) and cycling time (Tc, the time a receptor needs to complete a round trip). Relationship analyses revealed that nc increases linearly with increasing t½ and decreases exponentially with increasing Tc. For commonly observed t½ and Tc values, it was calculated th
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Melkes, Barbora, Vendula Markova, Lucie Hejnova та Jiri Novotny. "β-Arrestin 2 and ERK1/2 Are Important Mediators Engaged in Close Cooperation between TRPV1 and µ-Opioid Receptors in the Plasma Membrane". International Journal of Molecular Sciences 21, № 13 (2020): 4626. http://dx.doi.org/10.3390/ijms21134626.

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The interactions between TRPV1 and µ-opioid receptors (MOR) have recently attracted much attention because these two receptors play important roles in pain pathways and can apparently modulate each other’s functioning. However, the knowledge about signaling interactions and crosstalk between these two receptors is still limited. In this study, we investigated the mutual interactions between MOR and TRPV1 shortly after their activation in HEK293 cells expressing these two receptors. After activation of one receptor we observed significant changes in the other receptor’s lateral mobility and vic
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Jia, Huilin, Xingli He, Tengfei Jiang, and Fanzhi Kong. "Roles of Bile Acid-Activated Receptors in Monocytes-Macrophages and Dendritic Cells." Cells 14, no. 12 (2025): 920. https://doi.org/10.3390/cells14120920.

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Bile acids (BAs), essential for lipid metabolism and fat-soluble vitamin absorption, also act as signaling molecules that regulate immune homeostasis. This review focuses on the roles of four key BA-activated receptors, farnesoid X receptor (FXR), G protein-coupled bile acid receptor 1 (GPBAR1), liver X receptors (LXRs), and vitamin D receptor (VDR), in modulating the functions of monocytes-macrophages, and dendritic cells (DCs). The biological synthesis, transport, and metabolism of BAs were discussed and highlighted the feedback mechanisms regulating the synthesis and enterohepatic circulati
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Roddey, J. C., and G. A. Jacobs. "Information theoretic analysis of dynamical encoding by filiform mechanoreceptors in the cricket cercal system." Journal of Neurophysiology 75, no. 4 (1996): 1365–76. http://dx.doi.org/10.1152/jn.1996.75.4.1365.

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1. The stimulus/response properties of 20 mechanosensory receptors in the cricket cercal sensory system were studied using electrophysiological techniques. These receptors innervated filiform hairs of various lengths and directional selectivities. Previous studies have characterized the sensitivity of such cells to the direction of air currents and to the amplitude of sinusoidal stimuli. In the experiments reported here, the quantity and quality of information encoded in the receptors' elicited responses about the dynamics of more complex air current waveforms were characterized. 2. Based on a
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Xie, Peng, Junjie Zhang, Baiyu Chen, et al. "Computational Methods for Understanding the Selectivity and Signal Transduction Mechanism of Aminomethyl Tetrahydronaphthalene to Opioid Receptors." Molecules 27, no. 7 (2022): 2173. http://dx.doi.org/10.3390/molecules27072173.

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Opioid receptors are members of the group of G protein-couple receptors, which have been proven to be effective targets for treating severe pain. The interactions between the opioid receptors and corresponding ligands and the receptor’s activation by different agonists have been among the most important fields in opioid research. In this study, with compound M1, an active metabolite of tramadol, as the clue compound, several aminomethyl tetrahydronaphthalenes were designed, synthesized and assayed upon opioid receptors. With the resultant compounds FW-AII-OH-1 (Ki = 141.2 nM for the κ opioid r
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Wicher, Dieter, and Fabio Miazzi. "Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors." Cell and Tissue Research 383, no. 1 (2021): 7–19. http://dx.doi.org/10.1007/s00441-020-03363-x.

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AbstractThe majority of insect olfactory receptors belong to two distinct protein families, the ionotropic receptors (IRs), which are related to the ionotropic glutamate receptor family, and the odorant receptors (ORs), which evolved from the gustatory receptor family. Both receptor types assemble to heteromeric ligand-gated cation channels composed of odor-specific receptor proteins and co-receptor proteins. We here present in short the current view on evolution, function, and regulation of IRs and ORs. Special attention is given on how their functional properties can meet the environmental a
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Wajant, Harald. "Death receptors." Essays in Biochemistry 39 (October 1, 2003): 53–71. http://dx.doi.org/10.1042/bse0390053.

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Death receptors [Fas/Apo-1/CD95, TNF-R1 [tumour necrosis factor (TNF) receptor 1], DR3 [death receptor 3], TRAIL-R1 [TNF-related apoptosis-inducing ligand receptor 1], TRAIL-R2, DR6, p75-NGFR [p75-nerve growth factor receptor], EDAR [ectodermal dysplasia receptor]] form a subgroup of the TNF-R superfamily that can induce apoptosis (programmed cell death) via a conserved cytoplasmic signalling module termed the death domain. Although death receptors have been recognized mainly as apoptosis inducers, there is growing evidence that these receptors also fulfil a variety of nonapoptotic functions.
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Tesis sobre el tema "Receptors"

1

Chu, Kwun Pok. "Computational studies of nuclear receptors : estrogen receptors, glucocorticoid receptors, and farnesoid X receptor." HKBU Institutional Repository, 2009. http://repository.hkbu.edu.hk/etd_ra/1058.

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Ott, Thomas Ruthard. "Receptor activation in GNRH receptors." Doctoral thesis, University of Cape Town, 2000. http://hdl.handle.net/11427/2700.

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Pettersson, Katarina. "Signal transduction via estrogen receptors (ERs) and estrogen receptor-related receptors (ERRs) /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4184-X/.

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Sokolovski, Alexandra. "Sigma-1 Receptors Modulate NMDA Receptor Function." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23652.

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The sigma-1 receptor (σ-1R) is an endoplasmic reticulum (ER) protein that modulates a number of ion channels. It is hypothesized that σ-1Rs activated with agonist translocate to the plasma membrane. The σ-1R potentiates N-methyl-D-aspartate Receptors (NMDARs), important constituents of synaptic plasticity. NMDARs are anchored in the plasma membrane by Postsynaptic Density Protein-95 (PSD-95). The mechanism behind σ-1R modulation of NMDARs is not known. The results of my investigation confirm that σ-1Rs localize extrasomatically. Following σ-1R activation, σ-1R localization to dendrites and pos
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Weaver, Richard Emyr. "Ligand-receptor interactions at the parathyroid hormone receptors." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531595.

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ZHANG, SHENGWEN. "THE OPIOID RECEPTOR-LIKE RECEPTOR ORL1: SIGNALING AND INTERACTION WITH OPIOID RECEPTORS." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1029419843.

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Zhang, Shengwen. "The opioid receptor-like receptor ORL1 signaling and interaction with opioid receptors /." Cincinnati, Ohio : University of Cincinnati, 2002. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=ucin1029419843.

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Meira, Guilherme Louzada Silva. "Analíse da expressão do receptor olfativo M93 em sistemas heterólogos." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-31082016-115408/.

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O sistema olfatório de mamífero pode discriminar milhares de odores presentes no meio ambiente. Aproximadamente 1000 diferentes receptores olfatórios (ORs) são expressos no epitélio olfatório (OE) do nariz, Os ORs detectam os odores e transmitem os sinais resultantes para o bulbo olfatório (OB) no cérebro. Os ORs pertencem a super família dos receptores acoplados a proteína G (GPCR) e apresentam sete domínios transmembrânicos putativos. Por razões desconhecidas, os ORs são retidos no retículo endoplasmático quando expressos em linhagens de células de mamíferos heterólogas. Provavelmente, prote
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Carvalhosa, Artur Aburad de. ""Pesquisa dos receptores de estrógeno (RE) e do receptor da progesterona (RP) in vivo e verificação da influência destes hormônios in vitro em duas linhagens de adenomas pelomórficos"." Universidade de São Paulo, 2001. http://www.teses.usp.br/teses/disponiveis/23/23141/tde-02042004-115521/.

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RESUMO A similaridade entre o tecido da mama e o da glândula salivar está bem estabelecida. A porção das estruturas acinares e ductais destes órgãos são basicamente semelhantes. Estes aspectos, associados ao fato de que uma coexistência de carcinomas da mama e de glândula salivar, têm sido relatados em uma incidência maior do que a esperada. Guiaram estudos tentando determinar a importância dos receptores de estrógeno e progesterona em adenomas pleomórficos (AP). A neoplasia é mais freqüente nas glândulas salivares e exibe uma predileção para o sexo feminino. Recentemente a presença do rece
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Tchetchelnitski, V. "Regulation of neurotrophin receptors by receptor-type protein tyrosine phosphatases." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1310477/.

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Reversible protein phosphorylation plays a key role in cell signalling during neural development and thus controls cell proliferation, survival, differentiation and function. Kinases and their counter-partners the phosphatases tightly regulate protein phosphorylation. In the developing nervous system the neurotrophin receptor family of protein tyrosine kinases (TrkA, B and C) are major players in this signalling network during normal neuron development and also in several diseases such as neuropathies, degenerative disorders and cancers. Recently, receptor-type protein tyrosine phosphatases (R
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Libros sobre el tema "Receptors"

1

Ronald, Kahn C., and Harrison Len C, eds. Insulin receptors. Liss, 1988.

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Renato, Lauro, and Pirro Roberto De, eds. Handbook on receptor research: Insulin receptors. Field Educational Italia, Acta Medica, 1985.

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1928-, Thompson James C., and Galveston International Symposium on Gastrointestinal Endocrinology: Receptors and Post-Receptor Mechanisms (2nd : 1989), eds. Gastrointestinal endocrinology: Receptors and post-receptor mechanisms. Academic Press, 1990.

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Michael, Conn P., ed. Receptors: Model systems and specific receptors. Academic Press, 1993.

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Reggio, Patricia H. The cannabinoid receptors. Humana, 2009.

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Reggio, Patricia H. The cannabinoid receptors. Humana, 2009.

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Björklund, Anders, Remi Quirion, and Tomas Hökfelt. Peptide receptors. Elsevier, 2003.

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Badr, Mostafa Z., ed. Nuclear Receptors. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78315-0.

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Rast, Jonathan, and Katherine Buckley, eds. Immune Receptors. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1944-5.

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Eyster, Kathleen M., ed. Estrogen Receptors. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1920-9.

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Capítulos de libros sobre el tema "Receptors"

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Müller, Judith M., and Roland Schüle. "Sex Steroid Receptors: Androgen Receptor, Estrogen Receptors, Progesterone Receptor." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_163.

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Müller, Judith M., and Roland Schüle. "Sex Steroid Receptors: Androgen Receptor, Estrogen Receptors, Progesterone Receptor." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-21573-6_163-1.

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Tasker, Andrew S., and David M. Pollock. "Endothelin Receptors and Receptor Antagonists." In Endothelin Receptors and Signaling Mechanisms. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-11672-2_2.

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Siess, W. "Platelet Receptors: The Thrombin Receptor." In Platelets and Their Factors. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60639-7_5.

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Miyazaki, Hitoshi, Motohiro Kondoh, Yasushi Masuda, Hirotoshi Watanabe, and Kazuo Murakami. "Endothelin Receptors and Receptor Subtypes." In Endothelin. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4614-7514-9_5.

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Oosterkamp, H. M., and R. Bernards. "Androgen Receptor and Estrogen Receptors." In Cancer Drug Discovery and Development. Humana Press, 2002. https://doi.org/10.1007/978-1-59259-153-4_16.

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Levitzki, Alexander. "Receptors." In Endocytosis. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-6904-6_2.

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Kapoor, B. G., and Bhavna Khanna. "Receptors." In Ichthyology Handbook. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-07844-0_15.

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Robertson, David, Yelena Parfyonova, Mikhail Menshikov, and Alan S. Hollister. "Receptors." In Handbook of Research Methods in Cardiovascular Behavioral Medicine. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4899-0906-0_14.

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Li, Guideng, and Jinxu Fang. "Receptors." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-27841-9_7092-4.

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Actas de conferencias sobre el tema "Receptors"

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Brill, Michael H., Doreen W. Bergeron, and William W. Stoner. "Trichromatic retinal model with adaptive contrast sensitivity and resolution." In OSA Annual Meeting. Optica Publishing Group, 1987. http://dx.doi.org/10.1364/oam.1987.thc4.

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A computer-simulated retina called IRIS is described which discriminates small differences in reflected light when these differences occur in a restricted domain of space and time and maintains sensitivity to these differences for a wide range of light environments. As prevailing light levels de crease and photon noise becomes significant, IRIS automatically reduces its spatiotemporal resolution to provide greater redundancy. The temporal resolution depends on light intensity because each receptor’s response is governed by photopigment kinetics whose rate increases with light level. The spatia
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Srinivasan, Visvanathan, Nayan Reddy, Adriana Brasoava, and David L. Wells. "Micro-Embossing of Polymeric Substrates for Fluidic Self-Assembly." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-14817.

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Fluidic Self-Assembly™ (FSA)™ has become a routine manufacturing process in the production of radio-frequency identification tags. FSA operates through the self-positioning of micro-devices into pre-prepared matching receptor sites in a substrate. Research at North Dakota State University has focused on extending the applications of FSA well-beyond the current production routine. This pursuit requires, among other modifications, substantive extrapolation of the size, depth, configuration, spacing and spatial density of receptor sites. Three different test wafer patterns (see Figure 5 for patte
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Watson, Andrew B. "Constraints on sensitivity of linear visual neurons." In OSA Annual Meeting. Optica Publishing Group, 1988. http://dx.doi.org/10.1364/oam.1988.tuh4.

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Many visual neurons linearly combine signals from the receptors or from other cells which themselves form linear combinations of receptor signals. In both cases, if the noise that limits cell performance is confined to the receptors, the peak sensitivity of the cell is entirely determined by the magnitude of the receptor noise and the normalized shape of the cells’ receptive field. This simple result may be used to estimate the receptor noise from the sensitivity of retinal or geniculate cells as well as to predict sensitivity of higher-order cells from that of lower-order cells. Consequences
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Hood, Donald C., and David G. Birch. "Adaptation of human cone receptors: Recordings of cone a-waves." In Advances in Color Vision. Optica Publishing Group, 1992. http://dx.doi.org/10.1364/acv.1992.fa4.

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Boynton and Whitten1 were the first to attempt a quantitative description of the physiology of of primate cone adaptation. Using Brown's technique2 to isolate the summed receptor potential responsible for the cone a-wave of the monkey's ERG, they concluded that substantial adaptation occurred at the level of the cone receptor. The amount of adaptation and the mechanisms involved, however, are still open to debate. Here we focus on the mechanisms of adaptation of human cone receptors.
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Chesla, Scott E., Bryan T. Marshall, and Cheng Zhu. "Measuring the Probability of Receptor Extraction From the Cell Membrane." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0262.

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Abstract Recently, there has been an increasing interest in measuring the interaction forces between cell adhesion receptors and their ligands [1–3]. These molecules are either anchored on the membrane of a cell or coated on the surface of a substratum. The two surfaces are joined together as a result of the formation of non-covalent bonds between the receptors and ligands. The forces are measured when the two surfaces are separated. In a theoretical paper published nineteen years ago, George Bell estimated the force required to break a receptor-ligand bond and that required to uproot the rece
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Nuzzo, G. "Fractional diffusion of membrane receptors in endocytosis pathway." In AIMETA 2022. Materials Research Forum LLC, 2023. http://dx.doi.org/10.21741/9781644902431-50.

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Abstract. In this paper the diffusion model representing the motion of membrane receptors with respect to virus endocytosis is considered in the context of applied mechanics. The unexpected behaviour of the receptor density that moves from higher concentrations in the unbound phase to lower concentration at the right of the virus surface is accounted for introducing a mechanical drift term in the governing equation so that the difference of concentrations, higher in the bounded phase and lower in the unbounded phase is accounted for in the receptor motion. Additionally, a non-gaussian model of
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Sadova, A. A., D. A. Dmitrieva, N. A. Safronova, et al. "PREPARATION OF GPCR ANTIBODY COMPLEX SAMPLES FOR CRYO-ELECTRON MICROSCOPY." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-211.

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G-protein-coupled receptors are extremely important therapeutic targets, and their study represents the primary task of modern structural biology. Obtaining GPCR structures is fraught with many difficulties, which can be overcome by the formation of receptor and antibody fragments complexes. In this work, we obtained 4 antibody fragments, previously successfully used for the determination of GPCR structures, which we plan to use in the future to solve structures of the receptors studied in our laboratory.
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Batista, Victor de Sousa, Lourival Rodrigues de Sousa Neto, Roberto Ribeiro Faria, Keli Cristina Barbosa dos Reis та Nailton Monteiro do Nascimento Júnior. "Post-processing of docking results through docking-based comparative intermolecular contacts analysis (dbCICA) of the α4β2 and α7 nicotinic acetylcholine receptors (nAChRs)". У VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020146.

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The nAChRs are pentameric ligand-gated ionic channels that respond to the endogenous neurotransmitter acetylcholine, with the α4β2 and α7 subtypes being highly expressed in human brain. Those receptors are involved in many neurologic disorders such as Alzheimer’s disease and Schizophrenia, as well as in nicotine addiction. In this context, molecular modelling is a powerful tool for designing novel ligands targeting those receptors. In the present work, we applied dbCICA1 to identify optimal docking conditions for these two receptors. The methodology and results are summarized bellow. Briefly,
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Karnik, Rohit, Seungpyo Hong, Suman Bose, et al. "Microfluidic Separation of Cells by Rolling on Patterned Receptors." In ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2008. http://dx.doi.org/10.1115/icnmm2008-62217.

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Cell separation based on markers present on the cell surface has extensive biological applications. However, current separation methods involve labeling and label removal steps which are often slow and intrusive. We envisioned that the ability to control the direction of transport of cells based on specific receptors on the cell surface without labeling and label removal steps would enable simple continuous-flow microfluidic cell separation systems with minimal processing steps and active components. We therefore explored whether receptor patterning could be used to direct the transport of cel
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Safronova, N. A., T. S. Kurkin, M. B. Shevtsov, et al. "SAMPLE PREPARATION OF A RECEPTOR ASSOCIATED WITH MULTIPLE SCLEROSIS PATHOGENESIS FOR STRUCTURAL STUDIES USING CRYOELECTRON MICROSCOPY." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-370.

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In this work, we study the GPCR class A receptor (rhodopsin-like) which is phylogenetically close to cysteinyl leukotriene and purine receptors. It is expressed in oligodendrocyte progenitor cells and regulates formation of the myelin sheath of neurons. To determine the structure of this receptor by cryoelectron microscopy, we created a stable and monomeric protein sample.
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Informes sobre el tema "Receptors"

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Rafaeli, Ada, and Russell Jurenka. Molecular Characterization of PBAN G-protein Coupled Receptors in Moth Pest Species: Design of Antagonists. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7593390.bard.

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The proposed research was directed at determining the activation/binding domains and gene regulation of the PBAN-R’s thereby providing information for the design and screening of potential PBAN-R-blockers and to indicate possible ways of preventing the process from proceeding to its completion. Our specific aims included: (1) The identification of the PBAN-R binding domain by a combination of: (a) in silico modeling studies for identifying specific amino-acid side chains that are likely to be involved in binding PBAN with the receptor and; (b) bioassays to verify the modeling studies using mut
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Rafaeli, Ada, Russell Jurenka, and Daniel Segal. Isolation, Purification and Sequence Determination of Pheromonotropic-Receptors. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7695850.bard.

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Moths constitute a major group of pest insects in agriculture. Pheromone blends are utilised by a variety of moth species to attract conspecific mates, which is under circadian control by the neurohormone, PBAN (pheromone-biosynthesis-activating neuropeptide). Our working hypothesis was that, since the emission of sex-pheromone is necessary to attract a mate, then failure to produce and emit pheromone is a potential strategy for manipulating adult moth behavior. The project aimed at identifying, characterising and determining the sequence of specific receptors responsible for the interaction w
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Lubahn, Dennis B. Breast Cancer Associated Estrogen Receptors: Catechol Estrogen Receptors in ER-Minus Mice. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada396453.

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Lubahn, Dennis B. Breast Cancer Associated Estrogen Receptors: Catechol Estrogen Receptors in ER-Minus Mice. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada391322.

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Czekay, Ralf-Pater, and Marilyn Farquhar. Relationship Between Scavenger Receptors and uPA:PAI-l and uPA Receptors in Breast Cancer. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada338927.

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Czekay, Ralf-Peter, and Marilyn Farquhar. Relationship Between Scavenger Receptors and uPA:PAI-1 and uPA Receptors in Breast Cancer. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/adb241037.

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DiRenzo, James. Inhibition of Estrogen Receptor Action by the Orphan Receptors, SHP and DAX-1. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada403608.

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DiRenzo, James. Inhibition of Estrogen Receptor Action by the Orphan Receptors, SHP and DAX-1. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412765.

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DiRenzo, James. Inhibition of Estrogen Receptor Action by the Orphan Receptors, SHP and DAX-1. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada419517.

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Direnzo, James. Inhibition of Estrogen Receptor Action by the Orphan Receptors, SHP and DAX-1. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada393316.

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