Bibliografías temáticas / Ring opening of azirine and aziridines

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Literatura académica sobre el tema "Ring opening of azirine and aziridines"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 13 de febrero de 2022

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Artículos de revistas sobre el tema "Ring opening of azirine and aziridines"

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Carramiñana, Victor, Ana M. Ochoa de Retana, Francisco Palacios y Jesús M. de los Santos. "Synthesis of α-Aminophosphonic Acid Derivatives Through the Addition of O- and S-Nucleophiles to 2H-Azirines and Their Antiproliferative Effect on A549 Human Lung Adenocarcinoma Cells". Molecules 25, n.º 15 (22 de julio de 2020): 3332. http://dx.doi.org/10.3390/molecules25153332.

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This work reports a straightforward regioselective synthetic methodology to prepare α-aminophosphine oxides and phosphonates through the addition of oxygen and sulfur nucleophiles to the C–N double bond of 2H-azirine derivatives. Determined by the nature of the nucleophile, different α-aminophosphorus compounds may be obtained. For instance, aliphatic alcohols such as methanol or ethanol afford α-aminophosphine oxide and phosphonate acetals after N–C3 ring opening of the intermediate aziridine. However, addition of 2,2,2-trifluoroethanol, phenols, substituted benzenthiols or ethanethiol to 2H-azirine phosphine oxides or phosphonates yields allylic α-aminophosphine oxides and phosphonates in good to high general yields. In some cases, the intermediate aziridine attained by the nucleophilic addition of O- or S-nucleophiles to the starting 2H-azirine may be isolated and characterized before ring opening. Additionally, the cytotoxic effect on cell lines derived from human lung adenocarcinoma (A549) and non-malignant cells (MCR-5) was also screened. Some α-aminophosphorus derivatives exhibited very good activity against the A549 cell line in vitro. Furthermore, selectivity towards cancer cell (A549) over non-malignant cells (MCR-5) has been detected in almost all compounds tested.
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Huck, Lena, Juan F. González, Elena de la Cuesta y J. Carlos Menéndez. "Three-component synthesis of highly functionalized aziridines containing a peptide side chain and their one-step transformation into β-functionalized α-ketoamides". Beilstein Journal of Organic Chemistry 12 (8 de agosto de 2016): 1772–77. http://dx.doi.org/10.3762/bjoc.12.166.

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A sequential three-component process is described, starting from 3-arylmethylene-2,5-piperazinediones and involving a one-pot sequence of reactions achieving regioselective opening of the 2,5-diketopiperazine ring and diastereoselective generation of an aziridine ring. This method allows the preparation of N-unprotected, trisubstituted aziridines bearing a peptide side chain under mild conditions. Their transformation into β-trifluoroacetamido-α-ketoamide and α,β-diketoamide frameworks was also achieved in a single step.
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Wosińska-Hrydczuk, Marzena, Przemysław J. Boratyński y Jacek Skarżewski. "Regioselective and Stereodivergent Synthesis of Enantiomerically Pure Vic-Diamines from Chiral β-Amino Alcohols with 2-Pyridyl and 6-(2,2′-Bipyridyl) Moieties". Molecules 25, n.º 3 (7 de febrero de 2020): 727. http://dx.doi.org/10.3390/molecules25030727.

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In this report, we describe the synthetic elaboration of the easily available enantiomerically pure β-amino alcohols. Attempted direct substitution of the hydroxyl group by azido-functionality in the Mitsunobu reaction with hydrazoic acid was inefficient or led to a diastereomeric mixture. These outcomes resulted from the participation of aziridines. Intentionally performed internal Mitsunobu reaction of β-amino alcohols gave eight chiral aziridines in 45–82% yield. The structural and configuration identity of products was confirmed by NMR data compared to the DFT calculated GIAO values. For 1,2,3-trisubstituted aziridines slow configurational inversion at the endocyclic nitrogen atom was observed by NMR at room temperature. Moreover, when aziridine was titrated with Zn(OAc)2 under NMR control, only one of two N-epimers directly participated in complexation. The aziridines underwent ring opening with HN3 to form the corresponding azido amines as single regio- and diastereomers in 90–97% yield. Different results were obtained for 1,2-disubstituted and 1,2,3-trisubstituted aziridines. For the later aziridines ring closure and ring opening occurred at different carbon stereocenters, thus yielding products with two inverted configurations, compared to the starting amino alcohol. The 1,2-disubstituted aziridines produced azido amines of the same configuration as the starting β-amino alcohols. To obtain a complete series of diastereomeric vic-diamines, we converted the amino alcohols into cyclic sulfamidates, which reacted with sodium azide in SN2 reaction (25–58% overall yield). The azides obtained either way underwent the Staudinger reduction, giving a series of six new chiral vic-diamines of defined stereochemistries.
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D’hooghe, Matthias, Hyun-Joon Ha y Lingamurthy Macha. "Deployment of Aziridines for the Synthesis of Alkaloids and Their Derivatives". Synthesis 51, n.º 07 (18 de febrero de 2019): 1491–515. http://dx.doi.org/10.1055/s-0037-1611715.

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Various (activated and non-activated) aziridines with diverse substitution patterns have been deployed successfully as starting materials for the synthesis of a wide variety of alkaloids via suitable functionalization and aziridine ring transformation. Alternatively, the preparation and interception of reactive aziridine intermediates has also been shown to constitute a valid approach toward alkaloid synthesis. This review summarizes aziridine-mediated syntheses of alkaloids, in which the aziridine is mobilized as either a substrate or an advanced synthetic intermediate.1 Introduction2 Alkaloids Synthesis from Aziridine Starting Materials2.1 (2R)- and (2S)-Hydroxymethyl-N-(1-phenylethyl)aziridines2.2 N-Benzylaziridine-2-carboxylates2.3 2-Substituted N-Tosyl- or N-Tritylaziridines2.4 2,3-Disubstituted N-Cbz- or N-Tosylaziridines2.5 N-DMB-aziridines3 Alkaloids Synthesis from Aziridines as Key Advanced Synthetic Intermediates3.1 Alkylative Aziridine Ring Opening3.2 Arylative Aziridine Ring Opening3.3 Ring Expansion3.4 Oxidative Aziridine Ring Opening3.5 Heteroatomic Nucleophilic Aziridine Ring Opening3.6 Reductive Aziridine Ring Opening4 Conclusion
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Cytlak, T., M. Saweliew, M. Kubicki y H. Koroniak. "Synthesis of trifluoromethyl γ-aminophosphonates by nucleophilic aziridine ring opening". Organic & Biomolecular Chemistry 13, n.º 39 (2015): 10050–59. http://dx.doi.org/10.1039/c5ob01411e.

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Gleede, Tassilo, Louis Reisman, Elisabeth Rieger, Pierre Canisius Mbarushimana, Paul A. Rupar y Frederik R. Wurm. "Aziridines and azetidines: building blocks for polyamines by anionic and cationic ring-opening polymerization". Polymer Chemistry 10, n.º 24 (2019): 3257–83. http://dx.doi.org/10.1039/c9py00278b.

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Chakraborty Ghosal, Nirnita, Sougata Santra, Sudarshan Das, Alakananda Hajra, Grigory V. Zyryanov y Adinath Majee. "Organocatalysis by an aprotic imidazolium zwitterion: regioselective ring-opening of aziridines and applicable to gram scale synthesis". Green Chemistry 18, n.º 2 (2016): 565–74. http://dx.doi.org/10.1039/c5gc01323b.

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Bhandari, Sonal, Sravani Sana, Vandana Lahoti, Ramya Tokala y Nagula Shankaraiah. "Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines". RSC Advances 10, n.º 27 (2020): 16101–9. http://dx.doi.org/10.1039/d0ra00684j.

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Herein, we report a facile tandem approach for the synthesis of both spiro-oxindole-fused pyrroloindolines and benzofurano-pyrrolidines via a Lewis acid-catalyzed domino ring-opening annulation using activated spiro-aziridines and heteroarenes.
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Keniche, Assia, Samia Bellifa, Hafida Hassaine y Joseph Kajima Mulengi. "Development of new antibacterial agents". Medical Technologies Journal 1, n.º 2 (8 de junio de 2017): 31–32. http://dx.doi.org/10.26415/2572-004x-vol1iss2p31-32.

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Background: Antibiotics, as miraculous drugs, have been used extensively to confront fatal infection, even without prescriptions. However, the inappropriate and disproportionate use of antibiotics have led to the emergence of new drug-resistant bacteria1, which causes a high risk of serious diseases and dramatically aggravates the clinical complications in hospitals. Methods: By using the peptide coupling protocol, a simple straightforward synthesis of functionalized aziridines has been developed. By means of this synthetic strategy from readily available N-phtaloyl acide and 2-methylbenzosulfonate aziridine using DCC as coupling agent, new tosylates aziridines could be obtained. The coupling reactions occurred without a ring opening of the three membered ring. Results: This work describes new results of our ongoing research targeting new derivatives of biological interests. All the compounds were screened for their antibacterial activity; they all showed comparable moderate to good growth inhibitory activity with reference to tetracyclin and gentamicin. Conclusion: In conclusion, we reported the synthesis and a preliminary antibacterial evaluation of novel functionalized tosylaziridines. The synthetic strategy relies on the coupling reactions between tosylaziridines and amino acids. Moreover, and besides showing interesting antibacterial activities, the series of novel compounds can be further improved to serve as potential drug against nosocomial diseases.
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Siebert, Matthew R., Andrei K. Yudin y Dean J. Tantillo. "Cycloaddition/Ring Opening Reaction Sequences ofN-Alkenyl Aziridines: Influence of the Aziridine Nitrogen on Stereoselectivity". Organic Letters 10, n.º 1 (enero de 2008): 57–60. http://dx.doi.org/10.1021/ol702623d.

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Tesis sobre el tema "Ring opening of azirine and aziridines"

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Pulipaka, Aravinda B. "Intramolecular Ring Opening Reactions of Aziridines by π-Nucleophiles". Ohio University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1205514895.

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Lake, Fredrik. "C2- and C3-symmetric ligands via ring-opening of aziridines". Doctoral thesis, KTH, Chemistry, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3424.

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This thesis deals with the design and synthesis of chiralenantiopure nitrogencontaining ligands and the use of theseligands in asymmetric catalysis. A modular synthetic approachto enantiopure nitrogen-containing ligands was developed. Thesynthetic method is based on the ring-opening of activatedchiral aziridines by nitrogen nucleophiles. The aziridines areconveniently prepared from amino alcohols. The structure oftheaziridine and of the nucleophile can be extensively varied andlibraries of ligands are easily prepared. The use of primaryamines affords C2-symmetric bis(sulfonamides), whereas the use ofammonia affords C3-symmetric tris(sulfonamides) that can beelaborated into the corresponding tetra-amines.

The C2- and C3-symmetric ligands were used in the asymmetrictitaniummediated addition of diethylzinc to benzaldehyderesulting in modest enantioselection, 76% ee. A thoroughinvestigation of the reaction conditions revealed that theamount of Ti(OiPr)4has a decisive effect on the reaction rate and thestereochemical outcome of the reaction. The reaction timedecreased from about 90 hours to 15 minutes and theenantioselectivity changed from 26% of the (R)- enantiomer to72% of the (S)-enantiomer when the Ti(OiPr)4:benzaldehyde ratio was increased from 0.125:1 to1.48:1. Moreover, the titanium-mediated addition of diethylzincto benzaldehyde was studied in the presence of chiraladditives. The bis(sulfonamides) were also used in thecyclopropanation of cinnamyl alcohol. However, only lowenantioselection was observed, 27% ee.

The C3-symmetric tetra-amines were reacted to formazaphosphatranes. These weak acids were only partiallydeprotonated by the strong base KOtBu to form the correspondingproazaphosphatranes. The unexpectedly strong basicity of theproazaphosphatranes was believed to be due to steric effects assuggested by DFT calculations. The tetra-amines and thesulfonamides were used for the preparation of metal complexesof Lewis acidic metals such as titanium(IV) andzirconium(IV).

Keywords:asymmetric catalysis, aziridine, benzaldehyde,diethylzinc, enantioselective, ligand, proazaphosphatrane,ring-opening, sulfonamide, symmetry, titanium, zirconium

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Kasthuri, Mahesh. "Nouveaux anti-viraux pour le traitement des affections associées aux virus émergents". Thesis, Montpellier 2, 2011. http://www.theses.fr/2011MON20085.

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Dans un premier chapitre, nous avons présenté un historique succinct de la chimiothérapie antivirale et l'utilisation d'analogues nucléos(t)idiques. Nous nous sommes focalisés en particulier sur les nucléosides phosphonates acycliques (ANP) en tant qu'antiviraux potentiels. Dans un second chapitre, nous avons décrit la synthèse de β-céto, β-hydroxylamino et β-O-(benzyl)hydroxylamino ANP dérivés de l'adénine et de la cytosine. Les isomèrs (R) et (S)-β-hydroxy-ANP ont été préparés par dédoublement du racémique correspondant avec le (S)-MPA et l'attribution des configurations absolues a été effectuée par RMN et calculs de modélisation moléculaire. Nous avons aussi développé une méthodologie de synthèse de β-azido-ANP, ces derniers étant utilisés pour la préparation de β-amino-ANP par hydrogénation catalytique. Dans un troisième chapitre, nous avons présenté la synthèse des 2H-azirine et cis-aziridne-ANP et examiné lʹ ouverture de cycle comme voie d'accès à des ANP α,β-fonctionnalisés. Les propriétés biologiques de ces nouveaux ANP ont été évaluées en culture cellulaire sur un certain nombre de virus à ADN et ARN
In the first chapter, we presented a brief history of antiviral chemotherapy and use of nucleos(t)ide analogues, especially acyclic nucleoside phosphonates as potential antiviral agents. In the chapter-II we have successfully synthesized ¦Â-keto, ¦Â-hydroxylamino and ¦Â-O-(benzyl)hydroxylamino ANPs of adenine and cytosine derivatives. Then (R) and (S)-¦Â-hydroxy-ANPs were prepared via chiral resolution of racemic ¦Â-hydroxy-ANPs with (S)-MPA and assignment of absolute configuration was achieved using NMR and molecular modeling studies. We also developed a methodology for the synthesis of ¦Â-azido-ANPs and those were used for the preparation of ¦Â-amino-ANPs by catalytic hydrogenation. In third chapter, we synthesized 2H-azirine and cis-aziridine-ANPs and explored their ring opening to functionalized ¦Á,¦Â-ANPs. The novel ANPs obtained during this study were evaluated for their inhibitory effect on a number of DNA and RNA viruses in cell culture experiments
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Pulipaka, Aravinda B. "Intramolecular ring opening reactions of aziridines by [pi]-nucleophiles /". View abstract, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3306530.

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Fang, Fang. "Synthesis of Bicyclic and Tricyclic Analogues of Oxazolidinone". Ohio University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1357312054.

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Moss, Thomas. "New Methods in Stereoselective Alkylation : Enantio- and Diastereoselective Ring Opening of Aziridines". Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516400.

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Ferguson, Alexandra. "Synthesis and ring-opening of NH-aziridine-2-carboxylates, and preparation of novel pyrazolo[3,4-d]pyrimidines for kinase-substrate identification". Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/11074.

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1: The ring-opening of aziridine-2-carboxylates dominates their reactivity, providing diverse, biologically relevant compounds. Less is known about the chemistry of NH-aziridine-2-carboxylates, owing to multi-step preparation, and lack of N-functionality to aid ring-opening. Building on the recent disclosure of an NH-aziridination methodology applicable to enones, the substrate scope was expanded to include enoates. Aziridination provided access to NH-aziridine-2-carboxylates in a single step from readily available starting materials. Treatment of the resulting aziridine-2-carboxylates with nucleophiles proceeded with high regio- and stereoselectivity, providing access to natural and unnatural amino acid derivatives (Scheme 1).[Molecular structure diagrams appear here. To view, please open pdf attachment] Scheme 1: The synthesis and ring-opening of aziridine-2-carboxylates 2: Identification of kinase protein-substrate sets is crucial to further understand cellular processes, but is challenging with known methodology. Previous study had proposed a new methodology, incorporating two known strategies, bump-hole inhibition and photo-affinity labelling. Novel C3-aryl pyrazolo[3,4-d]pyrimidines were designed for the purpose (Fig. 1), although preparation of the compounds had proved challenging, with several key steps in the synthesis of analogues low-yielding and lengthy. A new synthetic route was developed, using hydrazone allylation to establish the α-tertamine functionality of the pyrazolo[3,4-d]pyrimidines. A late-stage oxidative cleavage was used to re-connect with the original synthetic strategy, to provide access to the C3-hydro analogues. Application of the revised route to the synthesis of the target compounds, using an alternative enol ether for C3-aromatic installation, provided access to two novel pyrazolo[3,4-d]pyrimidines for testing. [Molecular structure diagrams appear here. To view, please open pdf attachment] Fig. 1: C3-aryl pyrazolo[3,4-d]pyrimidines
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Zhang, Jianbin. "Ring-opening of cycloalkane epoxides and aziridines with aromatic amines : toward the total synthesis of pactamycin". Thèse, 2009. http://hdl.handle.net/1866/3794.

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Résumé Cette thèse consiste en trois thèmes résumés dans les paragraphes ci-dessous. L’influence de différents groupements protecteurs du groupe hydroxyle lors des réactions d’ouverture des cis- et trans- 3-hydroxy-1,2-époxycycloalcanes a été étudiée. Il a été montré que Yb(OTf)3 constituait un catalyseur doux pour l’ouverture régiosélective de cycles afin d’obtenir les -anilino cycloalcanols correspondants avec de bons rendements. Le chauffage du milieu réactionnel dans le toluène comme solvant a permis d’augmenter la cinétique de la réaction, au dépend du rendement. La partie aniline a été régiosélectivement introduite en position vicinale du groupe hydroxyle ou éther afin d’obtenir un unique régioisomère. La même tendance a été observée avec les époxydes du 3-azidocyclohex-1-ène et du 3-carbamate correspondant. Le temps de réaction a été réduit lorsque Yb(OTf)3 a été dissous dans l’acétonitrile. Le triflate d’ytterbium (III) a également été utilisé comme catalyseur pour l’ouverture de cycle régiosélective d’aziridines non-activées sur des cyclohexanes portant des substituants azotures ou éthers de benzyle. L’ion azoture ou l’aniline forment les produits trans correspondants, donnant alors accès à des diamines vicinales avec de bons rendements. Un éther ω-alcoxy p-méthoxybenzylique racémique, inhibiteur de HDAC, a été ainsi préparé en huit étapes synthétiques (rendement total de 26%) à partir du 1-((tert-butyldiphénylsilyl)oxy)hept-6-èn-2-ol. Ceci représente un progrès par rapport à la précédente méthode (9 étapes, rendement total de 16%). La métathèse croisée se montre particulièrement efficace et pratique dans cette stratégie et l’alkylation par le trichloroacétimidate de p-méthoxybenzyle en présence de Sc(OTf)3 améliore le rendement global de la synthèse. Un aminoalcool présent dans la pactamycine et contenant le squelette carboné, les groupements fonctionnels et la stéréochimie requise a été synthétisé en 27 étapes à partir de la L-thréonine. La méthodologie décrite dans cette thèse permet la synthèse de cet intermédiaire clé à l’échelle multigramme.
Abstract Ring-opening reactions of epoxides and aziridines have been extensively studied. The influence of different protecting groups on the hydroxyl group in the ring-opening reactions of cis- and trans- 3-hydroxy-1,2-cycloalkane epoxides with aromatic amines was studied. It was shown that Yb(OTf)3 in toluene was a mild catalyst for regioselective ring-opening, to give -anilino cycloalkanols in good yields. Heating the reaction mixture accelerated the rate of the reaction, albeit at the expense of yield. The aniline moiety was regioselectively added at the carbon furthest from the hydroxyl or ether group to yield a single regioisomer. The same trend was also observed with 3-azidocyclohex-1-ene epoxides and the corresponding 3-carbamates. The reaction time became shorter when acetonitrile was used as solvent, possibly due to the homogeneous medium. Ytterbium(III) triflate has also been used as the catalyst for the regioselective ring-opening of unactivated aziridines in cyclohexanes having an azide or benzyl ether substituent. Azide ion or aniline forms the corresponding trans-products giving access to vicinal diamines in good yields. A racemic ω-alkoxy p-methoxy benzyl ether HDAC inhibitor has been prepared in 8 synthetic steps (26% overall yield) from 1-((tert-butyldiphenylsilyl)oxy)hept-6-en-2-ol. This is an improvement over the published method (9 steps, 16% overall yield). The cross-metathesis method proved to be efficient and practical in this strategy, and alkylation using p-methoxybenzyl trichloroacetimidate in the presence of Sc(OTf)3 improved the overall yield of the synthesis. An amino alcohol that contains all the core carbons, functional groups and the required stereochemistry present in pactamycin was obtained starting from L-threonine over 27 steps. The methodology described in this thesis allows for a synthesis of this key intermediate on a multigram scale.
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Vale, João Rafael Campos do. "Photochemical synthesis and functional transformations of bicyclic vinyl aziridines". Master's thesis, 2015. http://hdl.handle.net/10362/17045.

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Aziridines, a class of organic compounds containing a three membered heterocycle with a nitrogen atom, are extremely valuable molecules in organic and medicinal chemistry. They are frequently used as versatile precursors in the synthesis of natural products, and many biologically active molecules possess the aziridine moiety. The reactivity of aziridines has been studied, for example, in ring-opening reactions with thiols. However, not much interest seems to be given to reactions of aziridines in aqueous media, despite the numberless advantages of using water as solvent in organic chemistry. The nucleophilic ring-opening reaction of aziridines in aqueous media was here explored. Following the Kaplan aziridine synthetic methodology, in which pyridinium salts undergo a photochemical transformation to give bicyclic vinyl aziridines, new aziridines were synthetized. Their nucleophilic ring-opening reaction in water under physiological conditions was investigated and a range of sulphur, nitrogen, carbon and oxygen nucleophiles tested. Thiols, anilines and azide proved to be good nucleophiles to react with the aziridines, giving the ring-opening product in moderate to good yields. The best results were obtained with thiols, more specifically with cysteine-derived nucleophiles. Preliminary results show that these bicyclic vinyl aziridines can modify calcitonin, a peptide containing two cysteine amino acids residues, grating them the potential to be used in bioconjugation as ligands to cysteine-containing proteins, or even as enzyme inhibitors of, for example, cysteine proteases. Additionally, exploratory investigations suggest that the separation of both enantiomers of the bicyclic vinyl aziridine can be performed by taking advantage of an enzymatic methodology for the resolution of racemic secondary alcohols. Both enantiomers would be highly valuable as precursors in the synthesis of enantiomerically pure molecules, as no other method is currently reported for their separation.
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Alagiri, K. "Metal-Mediated And Metal-Free Organic Transformations : C-H Functionalization Of Tertiary Amines, Synthesis Of Carbonyl Compounds And Ring-Opening Of Aziridines". Thesis, 2011. http://hdl.handle.net/2005/2061.

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Libros sobre el tema "Ring opening of azirine and aziridines"

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Almas, Jasmine. Rhodium-catalyzed ring opening of vinyl epoxides and vinyl aziridines with aniline nucleophiles. 2002, 2002.

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Capítulos de libros sobre el tema "Ring opening of azirine and aziridines"

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Nielsen, Lars P. C. y Eric N. Jacobsen. "Catalytic Asymmetric Epoxide Ring-opening Chemistry". En Aziridines and Epoxides in Organic Synthesis, 229–69. Weinheim, FRG: Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/3527607862.ch7.

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Wolf, Thomas y Frederik R. Wurm. "Chapter 10. Organocatalytic Ring-opening Polymerization Towards Poly(cyclopropane)s, Poly(lactame)s, Poly(aziridine)s, Poly(siloxane)s, Poly(carbosiloxane)s, Poly(phosphate)s, Poly(phosphonate)s, Poly(thiolactone)s, Poly(thionolactone)s and Poly(thiirane)s". En Polymer Chemistry Series, 406–72. Cambridge: Royal Society of Chemistry, 2018. http://dx.doi.org/10.1039/9781788015738-00406.

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Araki, S. y T. Hirashita. "Aziridine Ring Opening". En Science of Synthesis Knowledge Updates KU 2010/4, 1. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-107-00204.

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Ogawa, C. y S. Kobayashi. "Aziridine Ring Opening with Oxygen Nucleophiles". En Water in Organic Synthesis, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-206-00447.

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Ogawa, C. y S. Kobayashi. "Aziridine Ring Opening with Nitrogen Nucleophiles". En Water in Organic Synthesis, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-206-00450.

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Ogawa, C. y S. Kobayashi. "Aziridine Ring Opening with Sulfur Nucleophiles". En Water in Organic Synthesis, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-206-00453.

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Ogawa, C. y S. Kobayashi. "Noncatalyzed Aziridine Ring Opening with Oxygen Nucleophiles". En Water in Organic Synthesis, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-206-00448.

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Ogawa, C. y S. Kobayashi. "Noncatalyzed Aziridine Ring Opening with Nitrogen Nucleophiles". En Water in Organic Synthesis, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-206-00451.

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Hof, K., K. M. Lippert y P. R. Schreiner. "Ring Opening of Aziridines". En Brønsted Base and Acid Catalysts, and Additional Topics, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00273.

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Inokuma, T. y Y. Takemoto. "Ring Opening of Aziridines". En Brønsted Base and Acid Catalysts, and Additional Topics, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00362.

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Actas de conferencias sobre el tema "Ring opening of azirine and aziridines"

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Braga, Antonio Luiz, Syed M. Salman, Sayyar Muhamamd, Oscar E. D. Rodrigues, Luciano Dornelles y Ricardo S. Schwab. "Copper Oxide Nanoparticles-Catalyzed Aziridine Ring Opening with Diaryl Diselenides Under Ionic Liquid as Reaction Medium". En 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0026-1.

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