Literatura académica sobre el tema "Solid-state nanopore"

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Artículos de revistas sobre el tema "Solid-state nanopore"

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Liu, Zewen, Yifan Wang, Tao Deng, and Qi Chen. "Solid-State Nanopore-Based DNA Sequencing Technology." Journal of Nanomaterials 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/5284786.

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The solid-state nanopore-based DNA sequencing technology is becoming more and more attractive for its brand new future in gene detection field. The challenges that need to be addressed are diverse: the effective methods to detect base-specific signatures, the control of the nanopore’s size and surface properties, and the modulation of translocation velocity and behavior of the DNA molecules. Among these challenges, the realization of the high-quality nanopores with the help of modern micro/nanofabrication technologies is a crucial one. In this paper, typical technologies applied in the field o
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Fried, Jasper P., Jacob L. Swett, Binoy Paulose Nadappuram, et al. "In situ solid-state nanopore fabrication." Chemical Society Reviews 50, no. 8 (2021): 4974–92. http://dx.doi.org/10.1039/d0cs00924e.

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This review summarises the development of in situ solid-state nanopore fabrication techniques. These techniques are democratising solid-state nanopore research by providing rapid and accessible methods to fabricate nanopores.
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Ma, Aorui. "Application and Development of Biomimetic Solid-State Nanopore in Biosensing Technique." Transactions on Materials, Biotechnology and Life Sciences 7 (December 24, 2024): 303–7. https://doi.org/10.62051/zqn14b37.

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Biomimetic solid-state nanopore is a nano-level technology, which can be effectively used for many detection work, including DNA sequencing. The design of biomimetic solid-state nanopore is inspired by biological ion channels. Biomimetic solid-state nanopore displays many advantages. It can increase the processing characteristics while it can also ensure the performance of similar biological ion channels. It also exhibits controllable surface chemical properties, making biomimetic solid nanopores have more application space. When compared with traditional biosensors, biomimetic solid nanopores
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Wu, Kaiyan. "Solid-State Nanopores Used for the Detection of DNA Molecules." Highlights in Science, Engineering and Technology 73 (November 29, 2023): 302–6. http://dx.doi.org/10.54097/hset.v73i.12996.

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Solid-state nanopore is crucial in dection of DNA molescules. DNA is made up of two antiparallel strands of polynucleotides. They are joined together by hydrogen bonds between complementary base pairs. The DNA structures are essential for the ability of genetic carrier to control gene expression, promote DNA recombination, and enhance mutagenesis. There are many ways to do DNA testing. Among these methods, nanopore have relatively small size which allows single-molecule detection. It is also less expensive. There are two kinds of nanopores, which are solid-state nanopore and biological nanopor
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Lei, Xin, Jiayan Zhang, Hao Hong, Zhishan Yuan, and Zewen Liu. "Controllable Shrinking Fabrication of Solid-State Nanopores." Micromachines 13, no. 6 (2022): 923. http://dx.doi.org/10.3390/mi13060923.

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Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy. Despite the most use of naturally biological nanopores before, solid-state nanopores are widely developed with strong robustness, controllable sizes and geometries, a wide range of materials available, as well as flexible manufacturing. Therefore, various techniques typically based on focused ion beam or electron beam have been explored to drill nanopores directly on free-standing nanofilms. To further reduce and sculpt the pore size and sh
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Eggenberger, Olivia M., Cuifeng Ying, and Michael Mayer. "Surface coatings for solid-state nanopores." Nanoscale 11, no. 42 (2019): 19636–57. http://dx.doi.org/10.1039/c9nr05367k.

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Takai, Natsumi, Kan Shoji, Tei Maki, and Ryuji Kawano. "Simple Fabrication of Solid-State Nanopores on a Carbon Film." Micromachines 12, no. 9 (2021): 1135. http://dx.doi.org/10.3390/mi12091135.

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Solid-state nanopores are widely used as a platform for stochastic nanopore sensing because they can provide better robustness, controllable pore size, and higher integrability than biological nanopores. However, the fabrication procedures, including thin film preparation and nanopore formation, require advanced micro-and nano-fabrication techniques. Here, we describe the simple fabrication of solid-state nanopores in a commercially available material: a flat thin carbon film-coated micro-grid for a transmission electron microscope (TEM). We attempted two general methods for nanopore fabricati
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Liu, Li Ping, Hong Wen Wu, Yang Xuan, et al. "Study on the Size Shrinking and Shape Changing of Solid-State Nanopores." Advanced Materials Research 189-193 (February 2011): 3218–21. http://dx.doi.org/10.4028/www.scientific.net/amr.189-193.3218.

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Nanopores etched in the solid-state membranes have become the hotpot of nanotechnology research. Various methods for fabricating solid-state nanopores have been developed and reported, but the fabrication of nanopore is also a difficult challenge. In this paper, we milled nanopores of different sizes in the free-stand and low-stress solid-state membranes. And then the area around nanopores were scanned with the diffused ion beam, we found that the sediment around will melt and the shape of the nanopore becomes circular.
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Cheng, Peng, Candong Zhao, Qinjie Pan, et al. "Detection of Biomolecules Using Solid-State Nanopores Fabricated by Controlled Dielectric Breakdown." Sensors 24, no. 8 (2024): 2420. http://dx.doi.org/10.3390/s24082420.

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Nanopore sensor technology is widely used in biomolecular detection due to its advantages of low cost and easy operation. In a variety of nanopore manufacturing methods, controlled dielectric breakdown has the advantages of a simple manufacturing process and low cost under the premise of ensuring detection performance. In this paper, we have made enhancements to the applied pulses in controlled dielectric breakdown and utilized the improved dielectric breakdown technique to fabricate silicon nitride nanopores with diameters of 5 to 15 nm. Our improved fabrication method offers the advantage of
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Soni, Gautam V., and Amit Meller. "Progress toward Ultrafast DNA Sequencing Using Solid-State Nanopores." Clinical Chemistry 53, no. 11 (2007): 1996–2001. http://dx.doi.org/10.1373/clinchem.2007.091231.

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Abstract Background: Measurements of the ionic current flowing through nanometer-scale pores (nanopores) have been used to analyze single DNA and RNA molecules, with the ultimate goal of achieving ultrafast DNA sequencing. However, attempts at purely electronic measurements have not achieved the signal contrast required for single nucleotide differentiation. In this report we propose a novel method of optical detection of DNA sequence translocating through a nanopore. Methods: Each base of the target DNA sequence is 1st mapped onto a 2-unit code, 2 10-bp nucleotide sequence, by biochemical con
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Tesis sobre el tema "Solid-state nanopore"

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Vlassarev, Dimitar. "DNA Characterization with Solid-State Nanopores and Combined Carbon Nanotube across Solid-State Nanopore Sensors." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10310.

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A DNA molecule passing through a nanopore in a liner and sequential fashion allows for unprecedented interrogation of the polymer. Adding transverse electrodes that are comparable in size and sensitive to the DNA molecule, can further the attempts to rapidly sequence DNA. Carbon nanotubes are comparable in size and interact strongly with the DNA molecule. This makes them an excellent choice for integration with nanopores. Only the section of the carbon nanotube in immediate proximity to the nanopore should be sensitive to the DNA molecules. Atomic layer deposition of metal-oxides passivates th
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Tumati, Raghu. "Solid-State Nanopore Characterization and Low noise Transimpedance Amplifier for Nanopore-Based Gene Sequencer." Fogler Library, University of Maine, 2008. http://www.library.umaine.edu/theses/pdf/TumatiR2008.pdf.

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Singer, Alon. "A solid-state nanopore-based platform for molecular diagnostics." Thesis, Boston University, 2012. https://hdl.handle.net/2144/32064.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>The ability to identify and characterize infectious pathogens is essential for proper diagnosis, treatment and disease management. Many pathogens display similar pathophysiological traits, but respond to diff
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Briggs, Kyle. "Solid-State Nanopores: Fabrication, Application, and Analysis." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38541.

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The work presented in this thesis is divided loosely into three main areas of interest: development of a novel method of solid-state nanopore fabrication; applications of this method to some of the open problems in the field; and analysis of nanopore data. The first of these occupies the majority of the research presented in this thesis, covering research dedicated to the development and characterization of a novel method of solid-state nanopore fabrication which achieves nanometer scale control over matter using simple and low cost circuitry. Termed controlled breakdown (CBD), this techniqu
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Zhang, Yuning. "Combined nanochannel-nanopore device for single- molecule DNA analysis and manipulation." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110722.

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Nanofluidic devices, containing features with dimensions of 1-100 nm, allow for the direct detection, analysis and manipulation of single molecule analytes. In particular, over the past ten years, there has been increasing interest in developing nanofluidic devices capable of analyzing DNA at the single-molecule level, with the goal of developing high throughput mapping and eventually sequencing technology. Part of this thesis will be focusing on single-molecular DNA detection using solid state nanopores. The nanopore fabrication technique via electron beam ablation will be presented. Noise re
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Kwok, Wing Hei Harold. "New Approach in Fabrication of Solid-State Nanopore for Bio-Sensing Applications." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32210.

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The 21st century marks the defining point of human history in terms of technological advancement. In 2014, we were at the edge of acquiring a complete understanding of the fundamental construct to all life forms. The capability to manipulate and recreate lives as desired will soon be at our hands and will eventually lead to the redefinition of life and humanity. This brave new world, for better or worse, will be stitched together by scientific breakthroughs in many disciplines. Nanopore fluidic system – and microfluidic in general – might be one of the key puzzles towards the future. It is
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Levine, Edlyn Victoria. "Extreme Liquid Superheating and Homogeneous Bubble Nucleation in a Solid State Nanopore." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493497.

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This thesis explains how extreme superheating and single bubble nucleation can be achieved in an electrolytic solution within a solid state nanopore. A highly focused ionic current, induced to flow through the pore by modest voltage biases, leads to rapid Joule heating of the electrolyte in the nanopore. At sufficiently high current densities, temperatures near the thermodynamic limit of superheat are achieved, ultimately leading to nucleation of a vapor bubble within the nanopore. A mathematical model for Joule heating of an electrolytic solution within a nanopore is presented. This model c
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Beamish, Eric. "Biomarker Assay Development and Sensing with Solid-State Nanopores." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39687.

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Broadly speaking, the work herein discussed encompasses the development of biomolecular assays for biomarker detection. Specific to the assays in this thesis is the design of reaction schemes that consider the unique requirements of one class of single-molecule sensors in particular: solid-state nanopores formed using a novel fabrication and conditioning technique discovered during this research at the University of Ottawa. We present three unique assays for the detection of different biomolecular targets. The first uses a class of DNA origami structures termed nanoswitches to translate
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Tahvildari, Radin. "Integrating Solid-State Nanopore Sensors within Various Microfluidic Arrays for Single-Molecule Detection." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35829.

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The miniaturization afforded by the integration of microfluidic technologies within lab-on-a-chip devices has greatly enhanced analytical capabilities in several key applications. Microfluidics has been utilized in a wide range of areas including sample preparation and analysis, DNA microarrays, cell detection, as well as environmental monitoring. The use of microfluidics in these applications offer many unique advantages: reduction in the required sample size, reduction in analysis time, lowered cost through batch fabrication, potentially higher throughput and the vision of having such device
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Jain, Tarun (Tarun Kumar). "Membrane transfer process for the creation of low-noise solid state nanopore devices." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/67619.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 81-83).<br>Nanopore sensors are an emerging technology whereby the modulation of a current trace upon passage of the analyte through the nanopore is used to infer the properties of the analyte. This technology is particularly attractive because it is label-free, rapid, and intrinsically single molecule. However, the ability to infer molecular properties with nanometer precision, either in size or sequencing, is obscured
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Libros sobre el tema "Solid-state nanopore"

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Leburton, Jean-Pierre, ed. Solid State Nanopores. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42336-9.

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Gershow, Marc Herman. Trapping single molecules with a solid state nanopore. 2008.

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Solid State Nanopores: From Fabrication to Biosensing. Springer International Publishing AG, 2023.

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Capítulos de libros sobre el tema "Solid-state nanopore"

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Zhao, Yuanzhe, Jie Zhang, Zepeng Sun, Zheqi Cao, Liqun Xu, and Jian Li. "Scheme Design and Challenges of DNA Sequencing Terminal Equipment Based on Solid-State Nanopore Sequencing." In Lecture Notes in Mechanical Engineering. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-97-7887-4_13.

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Abstract Nanopore sequencing has become the primary technology for modern DNA sequencing. Solid nanopores are favored for their cost-effectiveness, stability, and scalability, particularly for portable applications. This paper presents a new design for a portable solid-state nanopore sequencing device based on the Linux platform. It employs a cutting-edge biological sequencing chip with a nanopore channel to capture through-hole data. Electrical signals from the chip are processed to create DNA sequence data files. The Linux-based Raspbian OS serves as the control terminal, facilitating seamle
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Yu, Ru-Jia, Shaochuang Liu, Yi-Lun Ying, and Yi-Tao Long. "Protein Profiling by a Confined Nanopore." In Solid State Nanopores. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42336-9_5.

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Kim, Kyung Hoon, Min Jung Lee, Chul Kyu Kim, et al. "Nano-Imprinted Ultrahigh-Density Nanopore Arrays." In Solid State Phenomena. Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/3-908451-31-0.1269.

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Chen, Kaikai, and Ulrich F. Keyser. "Solid-State Nanopore Sensing Enhanced by Designed DNA Nanostructures." In Solid State Nanopores. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42336-9_4.

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Venkatesan, Bala Murali, and Rashid Bashir. "Solid-State Nanopore Sensors for Nucleic Acid Analysis." In Nanopores. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-8252-0_1.

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Fu, Jian Zhong, Xiao Bing Mi, Yong He, and Zi Chen Chen. "Modeling of the Ionized Fluid Flow through a Cone-Shaped Nanopore." In Solid State Phenomena. Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/3-908451-30-2.1089.

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Oh, Han Jun, Kyung Wook Jang, Jong Ho Lee, et al. "Effects of Annealing Treatment of Aluminum Substrate on Nanopore Arrangements in Anodic Alumina." In Solid State Phenomena. Trans Tech Publications Ltd., 2006. http://dx.doi.org/10.4028/3-908451-25-6.549.

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Li, Jiali, and Jene A. Golovchenko. "Solid-State Nanopore for Detecting Individual Biopolymers." In Micro and Nano Technologies in Bioanalysis. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-483-4_7.

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Lin, Yao, Qiao Li, Shao-Chuang Liu, Si-Min Lu, Yi-Lun Ying, and Yi-Tao Long. "Chapter 4. Solid-state Nanopore Confinement for Single Molecule Detection." In Confining Electrochemistry to Nanopores. Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781788013260-00118.

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Zahid, Osama K., and Adam R. Hall. "Helium Ion Microscope Fabrication of Solid-State Nanopore Devices for Biomolecule Analysis." In Helium Ion Microscopy. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-41990-9_18.

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Actas de conferencias sobre el tema "Solid-state nanopore"

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Liu, Shulei, and Yin Zhang. "Controlling the Solid-state Nanopore Size Using Electric Fields." In 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2024. http://dx.doi.org/10.1109/nems60219.2024.10639901.

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Liu, Shulei, and Yin Zhang. "Controlling the Solid-State Nanopore Size Using Electric Fields." In 2024 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO). IEEE, 2024. https://doi.org/10.1109/3m-nano61605.2024.10769661.

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Akkan, Nihat, Koen Martens, Georges Gielen, Pol Van Dorpe, and Anne S. Verhulst. "Detectability limits of single proteins with nanopore-based voltage and ionic-current sensing." In 2024 IEEE European Solid-State Electronics Research Conference (ESSERC). IEEE, 2024. http://dx.doi.org/10.1109/esserc62670.2024.10719530.

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Das, Aurojyoti, Qiuyang Lin, Yixiong Hu та ін. "A 376μW per-channel, Drift-tolerant Translocation Recording Frontend with Event Detection for Nanopore Sensor Arrays". У 2024 IEEE European Solid-State Electronics Research Conference (ESSERC). IEEE, 2024. http://dx.doi.org/10.1109/esserc62670.2024.10719545.

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Wang, Luda, Ruiyang Song, and Ningran Wu. "Atomically Thin Graphene Nanopore Based MEMS Iontronic Devices for Sensing, Separation, and Energy Applications." In 2024 IEEE 17th International Conference on Solid-State & Integrated Circuit Technology (ICSICT). IEEE, 2024. https://doi.org/10.1109/icsict62049.2024.10831631.

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Sankman, Joey. "Tutorial: Fundamental Circuits for Nanopower and Energy-Harvesting Applications." In 2025 IEEE International Solid-State Circuits Conference (ISSCC). IEEE, 2025. https://doi.org/10.1109/isscc49661.2025.11076116.

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Hu, Xiaojing, and Yin Zhang. "Distinguishing between dsDNA and DNA with a single-base mismatch using solid-state nanopores." In 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2024. http://dx.doi.org/10.1109/nems60219.2024.10639548.

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Zhao, Xiaojing, Deqiang Wang, Xiaojing Zhao, et al. "DNA translocation through solid-state nanopore." In 2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO). IEEE, 2017. http://dx.doi.org/10.1109/3m-nano.2017.8286280.

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Saharia, Jugal, Y. M. Nuwan D. Y. Bandara, and Lokesh Saharan. "Molybdenum Disulfide Solid-State Nanopores for Single-Molecule Biosensing." In ASME 2023 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/imece2023-116801.

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Abstract Solid-state nanopore (SSN) is a propitious class of sensors delivering single-molecule level readouts with advantages such as high-throughput and label-free detection. While biological nanopores have shown great promise as a tool for fast and low-cost DNA/RNA sequencing, their artificial counterparts — SSNs — are yet to achieve the base-to-base signal resolution required for such high-precision genomic applications. Silicon nitride is the ubiquitous membrane material for SSNs and even the thinnest silicon nitride membranes are still a few nm thick (housing several bases at a given tim
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Ma, Jian, Weiwei Zhao, Lei Liu, Jingjie Sha, and Yunfei Chen. "Shrinking Graphene Nanopore Using Electron-Beam-Induced Deposition for Single Molecule Detection." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-50246.

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Solid-state nanopore has already shown success of single molecule detection and graphene nanopore is potential for successful DNA sequencing. Here, we present a fast and controllable way to fabricate sub-5 nm nanopore on graphene membrane. The process includes two steps: sputtering a large size nanopore using a conventional focused ion beam (FIB) and shrinking the large nanopore to a few nanometers using scanning electron microscope (SEM). We also demonstrated the ability of the graphene nanopores fabricated in this manner to detect individual 48Kbp λ-DNA molecules.
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Informes sobre el tema "Solid-state nanopore"

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Golovchenko, Jene A., and Daniel Branton. Electrical Properties of Solid-State Nanopore Sensors. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada417079.

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