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Littérature scientifique sur le sujet « Bioengineered skin substitute »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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Articles de revues sur le sujet "Bioengineered skin substitute"

Oualla-Bachiri, Wasima, Ana Fernández-González, María I. Quiñones-Vico, and Salvador Arias-Santiago. "From Grafts to Human Bioengineered Vascularized Skin Substitutes." International Journal of Molecular Sciences 21, no. 21 (2020): 8197. http://dx.doi.org/10.3390/ijms21218197.

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The skin plays an important role in the maintenance of the human’s body physiological homeostasis. It acts as a coverage that protects against infective microorganism or biomechanical impacts. Skin is also implied in thermal regulation and fluid balance. However, skin can suffer several damages that impede normal wound-healing responses and lead to chronic wounds. Since the use of autografts, allografts, and xenografts present source limitations and intense rejection associated problems, bioengineered artificial skin substitutes (BASS) have emerged as a promising solution to address these prob

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Tavakoli, Shima, and Agnes S. Klar. "Bioengineered Skin Substitutes: Advances and Future Trends." Applied Sciences 11, no. 4 (2021): 1493. http://dx.doi.org/10.3390/app11041493.

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As the largest organ in the human body, the skin has the function of maintaining balance and protecting from external factors such as bacteria, chemicals, and temperature. If the wound does not heal in time after skin damage, it may cause infection or life-threatening complications. In particular, medical treatment of large skin defects caused by burns or trauma remains challenging. Therefore, human bioengineered skin substitutes represent an alternative approach to treat such injuries. Based on the chemical composition and scaffold material, skin substitutes can be classified into acellular o

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Curran, Monique P., and Greg L. Plosker. "Bilayered Bioengineered Skin Substitute (Apligraf??*)." BioDrugs 16, no. 6 (2002): 439–55. http://dx.doi.org/10.2165/00063030-200216060-00005.

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Hirsch, Scott D., Jeremy M. Powers, and Jennifer L. Rhodes. "Neonatal Soft Tissue Reconstruction Using a Bioengineered Skin Substitute." Journal of Craniofacial Surgery 28, no. 2 (2017): 489–91. http://dx.doi.org/10.1097/scs.0000000000003346.

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Widgerow, Alan David. "Bioengineered Skin Substitute Considerations in the Diabetic Foot Ulcer." Annals of Plastic Surgery 73, no. 2 (2014): 239–44. http://dx.doi.org/10.1097/sap.0b013e31826eac22.

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Tobin, Micaela J., Audrey K. Mustoe, Sasha Nickman, et al. "Comparing Amniotic Membranes to Other Bioengineered Skin Substitutes in Wound Healing: A Propensity Score-Matched Analysis." Journal of Clinical Medicine 14, no. 12 (2025): 4272. https://doi.org/10.3390/jcm14124272.

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Background/Objectives: The amniotic membrane, which is widely available and inexpensive, has received recent attention for its potential applications in wound healing. This is the first study to use a large database to examine the efficacy of amniotic membrane grafting compared to other skin substitutes. Methods: The TriNetX electronic health database was queried in October 2024 for patients with burns or chronic skin ulcers. Patients were stratified by treatment with amniotic membrane grafts or another skin substitute. These patients were then 1:1 propensity score-matched based on age, demogr

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Haldar, Swati, Akriti Sharma, Sumeet Gupta, Samrat Chauhan, Partha Roy, and Debrupa Lahiri. "Bioengineered smart trilayer skin tissue substitute for efficient deep wound healing." Materials Science and Engineering: C 105 (December 2019): 110140. http://dx.doi.org/10.1016/j.msec.2019.110140.

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Nicoletti, Giovanni, Marco Mario Tresoldi, Alberto Malovini, Marco Visaggio, Angela Faga, and Silvia Scevola. "Versatile use of dermal substitutes: A retrospective survey of 127 consecutive cases." Indian Journal of Plastic Surgery 51, no. 01 (2018): 046–53. http://dx.doi.org/10.4103/ijps.ijps_217_17.

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ABSTRACT Background: Dermal substitutes are currently largely used for the treatment of huge skin loss in patients in critical general health conditions, for the treatment of severe burns and to promote the healing process in chronic wounds. Aims: The authors performed a retrospective assessment of their experience with bioengineered skin to possibly identify the most appropriate clinical indication and management for each substitute. Materials and Methods: The study involved 109 patients with 127 skin defects repaired with dermal substitutes over a 9 years period, from 2007 to 2016. Hyalomatr

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Mollapour Sisakht, Mahsa, Mohammad Ali Nilforoushzadeh, Javad Verdi, Hamid Reza Banafshe, Zahra Safaei Naraghi, and Seyed Abdolreza Mortazavi-Tabatabaei. "Fibrin-collagen hydrogel as a scaffold for dermoepidermal skin substitute, preparation and characterization." Journal of Contemporary Medical Sciences 5, no. 1 (2019): 8–13. http://dx.doi.org/10.22317/jcms.v5i1.519.

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Objective: Bioengineered skin substitutes were created to address wound healing problems. Skin substitutes contains live human cells seeded onto a matrix to provide cytokine, growth factor and other proteins from ECM required to decrease healing time. These products are classified based on their durability, the cells seeded on them and their originality. In this study, we aimed to investigate fibrin-collagen hydrogel as a new scaffold to design a bilayer temporary skin equivalent. Methods: Fibrin gel was prepared by crosslinking fibrinogen with thrombin and mixing it with collagen type 1

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Knox, Rebecca L., Allen R. Hunt, John C. Collins, Marie DeSmet, and Sara Barnes. "Platelet-Rich Plasma Combined With Skin Substitute for Chronic Wound Healing: A Case Report." Journal of ExtraCorporeal Technology 38, no. 3 (2006): 260–64. http://dx.doi.org/10.1051/ject/200638260.

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Contemporary management of chronic wounds focuses on improving natural healing and individualization of treatment. Incorporating multiple therapies has become increasingly common. Of interest are autologous growth factors, which are especially important in chronic wound healing and may contribute to tissue formation and epithelialization. Autologous platelet concentrate or platelet-rich plasma (PRP) is a concentration of at least five autologous growth factors and has been shown to accelerate wound healing and may have infection-fighting properties. Chronic wound healing is complicated by both

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Thèses sur le sujet "Bioengineered skin substitute"

Bush, Katie Ann. "Designing Bioengineered Skin Substitutes Containing Microfabricated Basal Lamina Analogs to Enhance Skin Regeneration." Digital WPI, 2009. https://digitalcommons.wpi.edu/etd-dissertations/50.

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Bioengineered skin substitutes have been developed to treat burn and non-healing wounds; however limitations still hinder their clinical success rates. Optimizing these current design strategies requires an understanding of how biochemical and topographical features of the native tissue modulate keratinocyte processes involved in tissue functionality. In this thesis, a novel bioengineered skin substitute was developed that contains a microfabricated basal lamina analog that recapitulates the native microenvironment found at the dermal-epidermal junction (DEJ). In native skin, this microenvir

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Chapitres de livres sur le sujet "Bioengineered skin substitute"

Ouellette, E. Anne, Melissa Diamond, and Anna-Lena Makowski. "Outcomes of Using Bioengineered Skin Substitute (Apligraf®) for Wound Coverage in Dupuytren’s Surgery." In Dupuytren’s Disease and Related Hyperproliferative Disorders. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-22697-7_45.

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Zidarič, Tanja, Karin Stana Kleinschek, Uroš Maver, and Tina Maver. "Bioengineered Skin Substitutes." In SpringerBriefs in Molecular Science. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-21298-7_3.

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Lei, Pedro, Hui You, and Stelios T. Andreadis. "Bioengineered Skin Substitutes." In Methods in Molecular Biology. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-363-3_22.

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Datarkar, Abhay, and Shikha Tayal. "Management of Soft Tissue Injuries in the Maxillofacial Region." In Oral and Maxillofacial Surgery for the Clinician. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_49.

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AbstractSoft tissue injuries of head and neck are the most common injuries encountered by the maxillofacial surgeons during their clinical practice. Therefore, one must have a sound knowledge of the various types, their mechanisms of injuries and most importantly, the management of the same. This chapter discusses the classification system of all types of soft tissue injuries, and focuses on the principles of management of different types of the injuries, with emphasis on their mechanism and healing process. Numerous figures, box diagrams and case scenarios are added to make the chapter intere

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Chehelgerdi, M., S. Yousefiasl, M. Chehelgerdi, T. Artimani, E. Sharifi, and S. Pourmotabed. "Safety, Regulation and Clinical Translation." In Carrier-mediated Gene and Drug Delivery for Dermal Wound Healing. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671540-00265.

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There is an urgent and challenging public health problem of repairing or replacing damaged skin. Getting the immune system to accept and tolerate the new skin is the main problem in grafting, since autografts are seldom possible. New therapeutic approaches, such as artificial skin substitutes, may eventually make transplants from donor skin less common. Research on skin graft transplantation and other forms of permanent skin repair has progressed significantly over the years. Alternative skin treatments range from stem cell therapies to bioengineered acellular or cellular skin substitutes to d

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Varghese, Treesa, Beegam L. Ramlath, M. Unnimaya, and Jenny Jacob. "Recent Advances in Biomaterials and Device Technologies for Chronic Wound Healing and Tissue Repair." In Innovations and Applications of Advanced Biomaterials in Healthcare and Engineering. IGI Global, 2025. https://doi.org/10.4018/979-8-3373-1305-4.ch008.

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Wound healing is a highly complicated event, involving re-vascularization, and re-epithelialization, followed by cellular proliferation, and tissue remodeling. Recent technological interventions have great potential in managing a healthy wound environment, thus reducing inflammation and healing time while promoting tissue repair. In addition, these inventions enhance the biocompatibility of wounds and improve the patient's quality of life. Major technological breakthroughs include self-healing hydrogels, hydrocolloids, hydro-fibers, surgical sutures, wearable wound monitoring systems, environm

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