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Littérature scientifique sur le sujet « Cats as laboratory animals »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 24 février 2023

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Articles de revues sur le sujet "Cats as laboratory animals"

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Lobova, D., V. Kleinova, J. Konvalinova, P. Cerna, and D. Molinkova. "Laboratory diagnostics of selected feline respiratory pathogens and their prevalence in the Czech Republic." Veterinární Medicína 64, No. 1 (January 23, 2019): 25–32. http://dx.doi.org/10.17221/93/2017-vetmed.

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Respiratory problems in cats have a multifactorial character. Therapy without the detection of pathogen is often ineffective. Our study was therefore focused on the detection of important feline respiratory bacterial pathogens such as Mycoplasma felis, Chlamydia felis and Bordetella bronchiseptica and viral pathogens such as Felid alphaherpesvirus-1 and feline calicivirus. The goal of this study was to map the occurrence of these pathogens in cat populations in the Czech Republic with the aim of introducing rapid and highly sensitive methods into routine diagnostics and to provide consulting s

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de Rivera, Christina, Jacqui Ley, Bill Milgram, and Gary Landsberg. "Development of a laboratory model to assess fear and anxiety in cats." Journal of Feline Medicine and Surgery 19, no. 6 (April 18, 2016): 586–93. http://dx.doi.org/10.1177/1098612x16643121.

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Objectives The objectives of this study were: (1) to develop a laboratory-based model to assess fear and anxiety in cats using the feline open-field test (OFT) and the feline human interaction test (HIT); and (2) to validate the model using diazepam, a known anxiolytic. Methods Laboratory-housed cats (n = 41) were first classified as fearful, mildly fearful or non-fearful by a technician familiar with the cats and also by veterinary behaviorists (GL, JL), by assessing the cats’ behavior in their home rooms. In experiment 1, each cat’s behavior was assessed in an OFT and an HIT. In experiment 2

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Fischer, Amy, Valerie AW Benka, Joyce R. Briggs, Joanne Maki, Kevin N. Morris, Kayla A. Myers, Linda Rhodes, George Robert Weedon, and Julie K. Levy. "Hybrid model intermediate between a laboratory and field study: A humane paradigm shift in feline research." Journal of Feline Medicine and Surgery 20, no. 9 (July 19, 2018): 803–10. http://dx.doi.org/10.1177/1098612x18791872.

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Objectives: Non-surgical contraceptives are under development to provide accessible, affordable and humane alternatives for the management of free-roaming cat populations. The objective of this project was to develop a research approach for promising non-surgical contraceptives using outbred cats in a simulated free-roaming setting, meeting high standards for both animal welfare and scientific rigor. Methods: A facility, specially constructed with indoor and outdoor living areas, was approved and regulated as both an animal shelter and a United States Department of Agriculture research facilit

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Ujwala Ashokrao Jadhao, Chatraguna Eknathrao Lagad, and Rajesh Kundlikrao Ingole. "Laboratory animal handling techniques, basic facilities and care: A review." World Journal of Biology Pharmacy and Health Sciences 12, no. 3 (December 30, 2022): 170–82. http://dx.doi.org/10.30574/wjbphs.2022.12.3.0239.

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Animals have been utilized in pharmaceutical scientific research and development for more than 300 years. Pharmaceutical items are a must in order to treat illnesses caused by viruses, bacteria, or homeostatic imbalance, among other causes. Pharmaceuticals must be thoroughly characterized via in vitro, in vivo, and clinical trial investigations in order to be used in humans. It is essential to quantify organism's in vivo using animals whose physiology and genetics are most similar to those of humans. Common animals used for laboratory experimental research are Cats, Rats, Dogs, Mice, Guinea pi

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Ruthrauff, Cassandra M., Julie Smith, and Leigh Glerum. "Primary Bacterial Septic Peritonitis in Cats: 13 Cases." Journal of the American Animal Hospital Association 45, no. 6 (November 1, 2009): 268–76. http://dx.doi.org/10.5326/0450268.

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The purpose of this paper is to describe the signalment, clinical signs, laboratory results, culture results, and response to treatment for primary septic peritonitis in cats. This is a retrospective study of 12 client-owned animals. Medical records were reviewed for clinical findings, laboratory results, microbial culture results, radiographic findings, diagnosis, treatment, and outcome. The overall mortality rate for this group of cats was 31%, consistent with previous reports of septic peritonitis in cats. All cats that were both bradycardic and hypothermic on presentation did not survive.

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Cossaboom, Caitlin M., Alexandra M. Medley, Jessica R. Spengler, Esther A. Kukielka, Grace W. Goryoka, Tiffany Baird, Swity Bhavsar, et al. "Low SARS-CoV-2 Seroprevalence and No Active Infections among Dogs and Cats in Animal Shelters with Laboratory-Confirmed COVID-19 Human Cases among Employees." Biology 10, no. 9 (September 11, 2021): 898. http://dx.doi.org/10.3390/biology10090898.

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Human-to-animal and animal-to-animal transmission of SARS-CoV-2 has been documented; however, investigations into SARS-CoV-2 transmission in congregate animal settings are lacking. We investigated four animal shelters in the United States that had identified animals with exposure to shelter employees with laboratory-confirmed COVID-19. Of the 96 cats and dogs with specimens collected, only one dog had detectable SARS-CoV-2 neutralizing antibodies; no animal specimens had detectable viral RNA. These data indicate a low probability of human-to-animal transmission events in cats and dogs in shelt

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Calvet, Guilherme Amaral, Sandro Antonio Pereira, Maria Ogrzewalska, Alex Pauvolid-Corrêa, Paola Cristina Resende, Wagner de Souza Tassinari, Anielle de Pina Costa, et al. "Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil." PLOS ONE 16, no. 4 (April 28, 2021): e0250853. http://dx.doi.org/10.1371/journal.pone.0250853.

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Background Infection by SARS-CoV-2 in domestic animals has been related to close contact with humans diagnosed with COVID-19. Objectives: To assess the exposure, infection, and persistence by SARS-CoV-2 of dogs and cats living in the same households of humans that tested positive for SARS-CoV-2, and to investigate clinical and laboratory alterations associated with animal infection. Methods Animals living with COVID-19 patients were longitudinally followed and had nasopharyngeal/oropharyngeal and rectal swabs collected and tested for SARS-CoV-2. Additionally, blood samples were collected for l

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Grotheer, Maike, Johannes Hirschberger, Katrin Hartmann, Noemi Castelletti, and Bianka Schulz. "Comparison of signalment, clinical, laboratory and radiographic parameters in cats with feline asthma and chronic bronchitis." Journal of Feline Medicine and Surgery 22, no. 7 (September 4, 2019): 649–55. http://dx.doi.org/10.1177/1098612x19872428.

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Objectives Feline asthma (FA) and feline chronic bronchitis (CB) are common respiratory conditions in cats, frequently referred to as ‘feline lower airway disease’. However, the aetiologies of both inflammatory airway diseases are probably different. Little is known about the differences in signalment, clinical signs, laboratory abnormalities and radiographic features between cats with these two airway diseases. The aim of the study was to investigate whether certain parameters can help in differentiating between both diseases, as distinguished by airway cytology. Methods Seventy-three cats wi

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Carlstead, Kathy, Janine L. Brown, and William Strawn. "Behavioral and physiological correlates of stress in laboratory cats." Applied Animal Behaviour Science 38, no. 2 (November 1993): 143–58. http://dx.doi.org/10.1016/0168-1591(93)90062-t.

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Platto, Sara, Agathe Serres, and Ai Jingyi. "Chinese College Students’ Attitudes towards Animal Welfare." Animals 12, no. 2 (January 10, 2022): 156. http://dx.doi.org/10.3390/ani12020156.

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Understanding the attitude of stakeholders towards animals is critical for the development and improvement of animal welfare in a country. College students from veterinary, animal, and life sciences majors represent future key stakeholders that will interact with professionals from animal industries. Therefore, it is critical to understand these college students’ attitudes towards animals and their knowledge about animal welfare. The present survey aimed to investigate Chinese college students’ concerns towards different animal classes (i.e., pets, farm, laboratory, and wild animals) through t

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Thèses sur le sujet "Cats as laboratory animals"

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Crawley, Allison Catherine. "Enzyme replacement therapy in a feline model of mucopolysaccharidosis type VI /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phc9107.pdf.

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Yogalingam, Gouri. "Molecular characterisation of feline MPS VI and evaluation of gene therapy /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phy54.pdf.

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Zarrinkalam, Krystyna. "Characterisation of osteoblast function in a feline model of mucopolysaccharidosis type VI." Title page, contents and introduction only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phz38.pdf.

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Addenda slip inserted in back. Includes bibliographical references (leaves 178-231). To further the understanding of the molecular mechanisms that contribute to the skeletal pathology of mucopolysaccharidosis type VI and to investigate the production of organic matrix by mucopolysaccharidosis VI osteoblasts

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Rose, Heidi Huffman. "SURVIVIN AND p53 EXPRESSION IN FELINE ORAL SQUAMOUS CELL CARCINOMA AND CORRELATION WITH PROGNOSIS." MSSTATE, 2008. http://sun.library.msstate.edu/ETD-db/theses/available/etd-03252008-191425/.

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Squamous cell carcinoma (SCC), the most common oral neoplasm of cats, demonstrates aggressive local invasion and has a poor prognosis. In humans, mutation of the p53 gene, crucial in cell cycle arrest and induction of apoptosis in damaged cells, is common in neoplasms. Survivin, an inhibitor of apoptosis, is frequently overexpressed in many types of human cancer. Studies suggest that wild-type p53 inhibits survivin expression, while mutated p53 does not. The purposes of this study included immunohistochemical examination of survivin and p53 expression in feline oral SCC and determination of a

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Rochlitz, Irene. "The welfare of cats kept in confined environments." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271003.

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Kirk, Robert George William. "Reliable animals, responsible scientists : constructing standard laboratory animals in Britain c.1919-1976." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1445731/.

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This thesis explores the attempt to construct a national supply of standard laboratory- animals in Britain between 1919 and 1976. The demand for a national supply of standard laboratory-animals is located in the formation during the interwar period of the discipline of biological standardization. In contrast to other disciplines within the sciences biological standardization placed great emphasis upon the routine replication of experimental results. In consequence the field of biological standardization problematized the laboratory-animal and sought its standardization in order to construct it

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Lazenby, Billie Theresa. "Do feral cats affect small animals? : a case study from the forests of southern Tasmania." Phd thesis, School of Biological Sciences, 2012. http://hdl.handle.net/2123/9990.

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Shapiro, Amanda June. "Australian companion animals and Coxiella burnetii (Q fever)." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15780.

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Introduction: Outbreaks of Q fever, an emerging worldwide zoonosis caused by Coxiella burnetii, were associated with periparturient companion animals in veterinary hospitals in Australia. These outbreaks initiated feline and canine seroprevalence studies, a national cat breeder survey, a molecular study looking for C. burnetii within food sources, and a canine vector-borne diseases study in dogs from Aboriginal communities, with the aim of increasing our understanding of the epidemiology of C. burnetii infection in companion animals. Method: Seroprevalence studies evaluated three methodologi

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Agarwal, Rajat. "A model for minimizing cost for housing laboratory mice." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0001241.

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Delpire, Veronique Charline. "Ethical schemes for the use of transgenic laboratory animals." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324118.

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Livres sur le sujet "Cats as laboratory animals"

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A, Suckow Mark, ed. The laboratory cat. Boca Raton, Fla: CRC Press, 1998.

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Scientific and humane issues in the use of random source dogs and cats in research. Washington, D.C: National Academies Press, 2009.

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Donnersberger, Anne B. A manual of anatomy and physiology: Laboratory animal, the cat. 3rd ed. Lexington, Mass: D.C. Heath, 1985.

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Willard, Michael D., and Harold Tvedten. Small animal clinical diagnosis by laboratory methods. 5th ed. St. Louis, Mo: Elsevier, 2012.

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Sodikoff, Charles. Laboratory profiles of small animal diseases: A guide to laboratory diagnosis. 2nd ed. St. Louis: Mosby, 1995.

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Laboratory profiles of small animal diseases: A guide to laboratory diagnosis. 3rd ed. St. Louis: Mosby, 2001.

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Bush, B. M. Interpretation of laboratory results for small animal clinicians. Oxford: Blackwell Scientific Publications, 1991.

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D, Willard Michael, Tvedten Harold, and Turnwald Grant H, eds. Small animal clinical diagnosis by laboratory methods. 2nd ed. Philadelphia: W.B. Saunders, 1994.

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Kustritz, Margaret V. Root. Clinical canine and feline reproduction: Evidence-based answers. Ames, Iowa: Wiley-Blackwell, 2010.

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Amemiya, T. Retinal and choroidal vascular changes and systemic diseases in rats: Corrosion cast and scanning electron microscopy. New York: Springer, 2003.

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Chapitres de livres sur le sujet "Cats as laboratory animals"

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Gaskell, R. M. "Herpesvirus of Cats." In Virus Diseases in Laboratory and Captive Animals, 219–32. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-2091-3_13.

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Blenden, Donald C., Manuel J. Torres-Anjel, and F. T. Satalowich. "Applications of Laboratory Technology in the Evaluation of the Risk of Rabies Transmissions by Biting Dogs and Cats." In Advances in Animal Welfare Science 1985, 221–46. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4247-9_12.

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Lakshmanan, Mageshwaran. "Laboratory Animals." In Introduction to Basics of Pharmacology and Toxicology, 13–36. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-5343-9_2.

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Gunn-Moore, Danièlle, and Kerry Simpson. "Pheochromocytoma in Cats." In Clinical Endocrinology of Companion Animals, 137–42. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch14.

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Gunn-Moore, Danièlle, and Kerry Simpson. "Hypoadrenocorticism in Cats." In Clinical Endocrinology of Companion Animals, 22–27. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch2.

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Gunn-Moore, Danièlle, and Kerry Simpson. "Insulinoma in Cats." In Clinical Endocrinology of Companion Animals, 240–44. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch22.

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Gunn-Moore, Danièlle. "Hypothyroidism in Cats." In Clinical Endocrinology of Companion Animals, 273–77. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch26.

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Peterson, Mark E. "Hyperthyroidism in Cats." In Clinical Endocrinology of Companion Animals, 295–310. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch29.

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Schenck, Patricia A., and Dennis Chew. "Hypocalcemia in Cats." In Clinical Endocrinology of Companion Animals, 326–34. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch32.

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Chew, Dennis, and Patricia A. Schenck. "Hypercalcemia in Cats." In Clinical Endocrinology of Companion Animals, 373–84. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997093.ch35.

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Actes de conférences sur le sujet "Cats as laboratory animals"

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Kulmakova, N. I. "PREVALENCE AND FEATURE OF OTODEKTOSIS IN CATS." In DIGEST OF ARTICLES ALL-RUSSIAN (NATIONAL) SCIENTIFIC AND PRACTICAL CONFERENCE "CURRENT ISSUES OF VETERINARY MEDICINE: EDUCATION, SCIENCE, PRACTICE", DEDICATED TO THE 190TH ANNIVERSARY FROM THE BIRTH OF A.P. Stepanova. Publishing house of RGAU - MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1853-9-2021-45.

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The prevalence and peculiarities of the course of otodectosis in cats in the conditions of the Vysota veterinary clinic (Moscow) have been studied. Animals of both sexes are at risk for the incidence of otodectosis; outbred and belonging to breeds (for example, Scottish); crossbred cats in a mixed way of keeping; cats under 6 years old; animals that have a lot of contacts with other animals. Otodectosis in the population of the city of Moscow is especially pronounced in the autumn-spring period.

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Veretnikov, A. A., O. N. Konyaeva, and V. A. Tolkachѐv. "Age-related incidence of calculus diagnosis in purebreds dogs and cats at home." In SCIENCE OF RUSSIA: GOALS AND OBJECTIVES. L-Journal, 2020. http://dx.doi.org/10.18411/sr-10-12-2020-42.

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A study of the age-related incidence of calculus diagnosis in certain breeds of dogs and cats was carried out. Because of the research, it was found that at all ages taken into account; dogs are most susceptible to animals of the Chihuahua Hua, Cocker Spaniel and Spitz breeds, and in cats - animals of the Scottish, British and Siamese breeds.

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Monteiro, B., C. Otis, L. Arendt-Nielsen, and E. Troncy. "Quantitative Sensory Testing in Dogs and Cats with Osteoarthritis-Related Pain: A Systematic Review." In Pain in Animals Workshop 2017: Abstracts. Schattauer GmbH, 2018. http://dx.doi.org/10.1055/s-0038-1660885.

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Koniar, Dusan, Libor Hargas, Zuzana Loncova, Frantisek Duchon, and Peter Beno. "Laboratory animals tracking in videosequences." In 2016 ELEKTRO. IEEE, 2016. http://dx.doi.org/10.1109/elektro.2016.7512134.

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Naida, Christopher G. "Construction Vibration Mitigation for Laboratory Animals." In Geotechnical Earthquake Engineering and Soil Dynamics V. Reston, VA: American Society of Civil Engineers, 2018. http://dx.doi.org/10.1061/9780784481462.030.

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Krasnikov, A. V. "SOME ASPECTS OF MAXILLOFACIAL SURGERY OF SMALL NONPRODUCTIVE ANIMALS." In DIGEST OF ARTICLES ALL-RUSSIAN (NATIONAL) SCIENTIFIC AND PRACTICAL CONFERENCE "CURRENT ISSUES OF VETERINARY MEDICINE: EDUCATION, SCIENCE, PRACTICE", DEDICATED TO THE 190TH ANNIVERSARY FROM THE BIRTH OF A.P. Stepanova. Publishing house of RGAU - MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1853-9-2021-42.

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An analytical review is presented, the purpose of which is todetermine the most important vectors when choosing approaches to reparative osteogenesis in dogs and cats with fractures of the bones of the upper and / or lower jaw. Medical care for all types of fractures should rely on such vectors of functionally stable osteosynthesis as adequate rigid fixation, minimally invasiveness, structural stability, safety and effectiveness of the new product's effect on bone regeneration and on the whole organism as a whole.

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Lukanc, Barbara, and Vladimira Erjavec. "Treating Burns in Cats and Dogs Using Medical Honey." In Socratic Lectures 7. University of Lubljana Press, 2022. http://dx.doi.org/10.55295/psl.2022.d11.

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Common causes of burns in small animals are household accidents or iatrogenic burns in veterinary clinics (electric heating pads…). Burns are usually treated as open wounds, where honey can be used as a dressing, that creates a moist healing environment, promotes tissue debridement, eliminates infections, has a deodorizing effect, and reduces inflammation, edema, and exudation. Honey also stimulates angiogenesis, promotes granulation tissue and epithelialization, and reduces scarring. It is important to minimise the potential contamination of burns. The high viscosity of honey acts as a physic

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Noble, C., E. Scott, A. Nolan, and J. Reid. "Initial Evidence to Support the Use of a Generic Health-Related Quality of Life Instrument to Measure Chronic Pain in Cats with Osteoarthritis." In Pain in Animals Workshop 2017: Abstracts. Schattauer GmbH, 2018. http://dx.doi.org/10.1055/s-0038-1660887.

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Dyulger, G. P. "UTERINE STROKE PIOMETER IN A DOG ASSOCIATED WITH OVARIOREMINANT SYNDROME (CLINICAL CASE)." In DIGEST OF ARTICLES ALL-RUSSIAN (NATIONAL) SCIENTIFIC AND PRACTICAL CONFERENCE "CURRENT ISSUES OF VETERINARY MEDICINE: EDUCATION, SCIENCE, PRACTICE", DEDICATED TO THE 190TH ANNIVERSARY FROM THE BIRTH OF A.P. Stepanova. Publishing house of RGAU - MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1853-9-2021-35.

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Pyometra of the uterine stump associated with the ovarian remnant syndrome is quite rare found in veterinary practice of small domestic animals (dogs and cats) and therefore the description of its particular case in a dog is undoubtedly of some interest to practicing doctors.

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Maxwell, Paul, Howard Jay Siegel, and Jerry Potter. "The ISTeC People-Animals-Robots laboratory: Robust resource allocation." In Rescue Robotics (SSRR). IEEE, 2009. http://dx.doi.org/10.1109/ssrr.2009.5424142.

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Rapports d'organisations sur le sujet "Cats as laboratory animals"

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Zurlo, Joanne. Institute of Laboratory Animals Research (ILAR). Fort Belvoir, VA: Defense Technical Information Center, March 2003. http://dx.doi.org/10.21236/ada416653.

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Shantyz, A. K., P. V. Miroshnichenko, E. S. Sadikova, and V. V. Menshenin. Changes in hematological and biochemical blood parameters in laboratory animals with experimental escherichiosis. Краснодарский научный центр по зоотехнии и ветеринарии, 2018. http://dx.doi.org/10.18411/88sh-e5337.

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Corscadden, Louise, and Arpaporn Sutipatanasomboon. What Is Operant Behavior And How To Study It. Maze Engineers, December 2022. http://dx.doi.org/10.55157/me2022127.

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Operant behavior describes a type of voluntary goal-directed actions in animals based on the repercussions of previous occurrences. It develops when animals learn to specifically respond to recurring situations based on the outcome of their past experience. American psychologist B.F. Skinner was the first to use operant to describe the behaviors he observed in his landmark experiments in laboratory animals. Operant behavior and conditioning refine the nuance between conscious and unconscious behavioral responses, which influence psychology, and applied behavior analysis, and improve our unders

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Corscadden, Louise, and Arpaporn Sutipatanasomboon. Rodent Tagging And Identification. ConductScience, January 2023. http://dx.doi.org/10.55157/cs20230109.

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Animal tagging is a means to identify and distinguish all the individual animals of interest, which applies to wildlife, farm, or laboratory animals. It involves attaching a tag to a specific animal part that contains a unique identifier for each animal. The identifier can be numbers, alphabets, or a combination of both that distinguish and track the animals throughout their lifespans. In rodents, tagging is the most popular identification approach. Typically, tags are made from metals and attached to the outer part of rodent ears, or the ear pinna. In rare circumstances, metal tags can also b

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Matthew, Gray. Data from "Winter is Coming – Temperature Affects Immune Defenses and Susceptibility to Batrachochytrium salamandrivorans". University of Tennessee, Knoxville Libraries, January 2021. http://dx.doi.org/10.7290/t7sallfxxe.

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Environmental temperature is a key factor driving various biological processes, including immune defenses and host-pathogen interactions. Here, we evaluated the effects of environmental temperature on the pathogenicity of the emerging fungus, Batrachochytrium salamandrivorans (Bsal), using controlled laboratory experiments, and measured components of host immune defense to identify regulating mechanisms. We found that adult and juvenile Notophthalmus viridescens died faster due to Bsal chytridiomycosis at 14 ºC than at 6 and 22 ºC. Pathogen replication rates, total available proteins on the sk

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Jung, Carina, Matthew Carr, Denise Lindsay, Eric Fleischman, and Chandler Roesch. Microbiome perturbations during domestication of the green June beetle (Cotinis nitida). Engineer Research and Development Center (U.S.), February 2022. http://dx.doi.org/10.21079/11681/43342.

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Animal-associated microbiomes are critical to the well-being and proper functioning of the animal host, but only limited studies have examined in-sect microbiomes across different developmental stages. These studies revealed large shifts in microbiome communities, often because of significant shifts in diet during insects’ life cycle. Establishing insect colonies as model laboratory organisms and understanding how to properly feed and care for animals with complex and dynamic life cycles requires improved data. This study examined laboratory raised green June beetles (Cotinis nitida) captured

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Shpigel, Nahum, Raul Barletta, Ilan Rosenshine, and Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7696510.bard.

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Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of a severe inflammatory bowel disease (IBD) in ruminants, known as Johne’s disease or paratuberculosis. Johne’s disease is considered to be one of the most serious diseases affecting dairy cattle both in Israel and worldwide. Heavy economic losses are incurred by dairy farmers due to the severe effect of subclinical infection on milk production, fertility, lower disease resistance and early culling. Its influence in the United States alone is staggering, causing an estimated loss of $1.5 billion to the agriculture indu

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Cahaner, Avigdor, Susan J. Lamont, E. Dan Heller, and Jossi Hillel. Molecular Genetic Dissection of Complex Immunocompetence Traits in Broilers. United States Department of Agriculture, August 2003. http://dx.doi.org/10.32747/2003.7586461.bard.

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Objectives: (1) Evaluate Immunocompetence-OTL-containing Chromosomal Regions (ICRs), marked by microsatellites or candidate genes, for magnitude of direct effect and for contribution to relationships among multiple immunocompetence, disease-resistance, and growth traits, in order to estimate epistatic and pleiotropic effects and to predict the potential breeding applications of such markers. (2) Evaluate the interaction of the ICRs with genetic backgrounds from multiple sources and of multiple levels of genetic variation, in order to predict the general applicability of molecular genetic marke

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Boisclair, Yves R., and Arieh Gertler. Development and Use of Leptin Receptor Antagonists to Increase Appetite and Adaptive Metabolism in Ruminants. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7697120.bard.

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Objectives The original project had 2 major objectives: (1) To determine the effects of centrally administered leptin antagonist on appetite and adaptive metabolism in the sheep; (2) To develop and prepare second-generation leptin antagonists combining high binding affinity and prolonged in vivo half-life. Background Periods of suboptimal nutrition or exaggerated metabolic activity demands lead to a state of chronic energy insufficiency. Ruminants remain productive for a surprisingly long period of time under these circumstances by evoking adaptations sparing available energy and nutrients. Th

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Morrison, Mark, and Joshuah Miron. Molecular-Based Analysis of Cellulose Binding Proteins Involved with Adherence to Cellulose by Ruminococcus albus. United States Department of Agriculture, November 2000. http://dx.doi.org/10.32747/2000.7695844.bard.

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At the beginning of this project, it was clear that R. albus adhered tightly to cellulose and its efficient degradation of this polysaccharide was dependent on micromolar concentrations of phenylacetic acid (PAA) and phenylpropionic acid (PPA). The objectives for our research were: i) to identify how many different kinds of cellulose binding proteins are produced by Ruminococcus albus; ii) to isolate and clone the genes encoding some of these proteins from the same bacterium; iii) to determine where these various proteins were located and; iv) quantify the relative importance of these proteins

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