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Littérature scientifique sur le sujet « Discriminatory Dissolution »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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Articles de revues sur le sujet "Discriminatory Dissolution"

Amaral Silva, Daniela, Jozef Al-Gousous, Neal M. Davies, et al. "Biphasic Dissolution as an Exploratory Method during Early Drug Product Development." Pharmaceutics 12, no. 5 (2020): 420. http://dx.doi.org/10.3390/pharmaceutics12050420.

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Dissolution testing is a major tool used to assess a drug product’s performance and as a quality control test for solid oral dosage forms. However, compendial equipment and methods may lack discriminatory power and the ability to simulate aspects of in vivo dissolution. Using low buffer capacity media combined with an absorptive phase (biphasic dissolution) increases the physiologic relevance of in vitro testing. The purpose of this study was to use non-compendial and compendial dissolution test conditions to evaluate the in vitro performance of different formulations. The United States Pharma

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Ashokraj, Yasvanth, Atul Daroi, Raja Gupta, et al. "Discriminatory Dissolution Method Development and Validation of Etoricoxib Tablets." Dissolution Technologies 23, no. 2 (2016): 30–34. http://dx.doi.org/10.14227/dt230216p30.

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Kaur, Parmar, and Bansal. "Evaluation of Different Techniques for Size Determination of Drug Nanocrystals: A Case Study of Celecoxib Nanocrystalline Solid Dispersion." Pharmaceutics 11, no. 10 (2019): 516. http://dx.doi.org/10.3390/pharmaceutics11100516.

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Celecoxib (CEL) Nanocrystalline Solid Dispersion (CEL_NCSD) was generated by spray drying CEL, mannitol (MAN) and sodium lauryl sulfate (SLS) from a solvent mixture of methanol, acetone and water. The purpose of the work was to determine the size of CEL nanocrystals, investigate agglomeration and inspect dissolution of CEL_NCSD. Size determination was challenging as CEL nanocrystals are embedded in the matrix of MAN. Firstly, neat CEL_NCSD was analyzed using Scherrer equation. Secondly, MAN was dissolved in an aqueous stabilizer medium to selectively measure the size of CEL nanocrystals. Raman

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Singh, SachinK, KK Srinivasan, K. Gowthamarajan, and GB Narayan. "Development and validation of discriminatory dissolution procedure for poorly soluble glyburide." Asian Journal of Pharmaceutics 4, no. 4 (2010): 205. http://dx.doi.org/10.4103/0973-8398.76744.

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Singla, N., G. D. Gupta, K. Kohli, and A. K. Singla. "A Discriminatory and Biorelevant Dissolution Test Method for Simvastatin Drug Products." Dissolution Technologies 16, no. 4 (2009): 11–13. http://dx.doi.org/10.14227/dt160409p11.

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Silva, Ana Paula Cappra, Leonardo Zanchetti Meneghini, Lisiane Bajerski, et al. "Discriminatory Dissolution Test for Tablets Containing a- and b-Thalidomide Polymorphs." Dissolution Technologies 20, no. 1 (2013): 19–25. http://dx.doi.org/10.14227/dt200113p19.

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Dharani, Sathish, Sogra F. Barakh Ali, Hamideh Afrooz, Mansoor A. Khan, and Ziyaur Rahman. "Development and Validation of a Discriminatory Dissolution Method for Rifaximin Products." Journal of Pharmaceutical Sciences 108, no. 6 (2019): 2112–18. http://dx.doi.org/10.1016/j.xphs.2019.01.020.

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Kaur, Sharanpreet, Navreet Kaur, Gursimran Kaur, and Prabhat Kumar. "A Review on Fluconazole." Journal for Research in Applied Sciences and Biotechnology 2, no. 3 (2023): 41–43. http://dx.doi.org/10.55544/jrasb.2.3.6.

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The improvement of a significant dissolution manner for drug merchandise with restrained water solubility has been a project to the pharmaceutical industry. fluconazole (BCS Class 1 drug) is an anti-fungal drug. There isn't any reputable dissolution medium to be had withinside the literature. In the prevailing study, parameters inclusive of solubility, medium pH, surfactant type, dissolution behaviour of formulations, impact of sink situations, stability, and discriminatory impact of dissolution checking out had been studied for the choice of a right dissolution medium. Results of solubility f

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Anumolu, Panikumar Durga, Sirisha Neeli, Haripriya Anuganti, Sathesh Babu Puvvadi Ranganatham, and Subrahmanyam Chavali Venkata Satya. "Development of dissolution test method for a telmisartan/amlodipine besylate combination using synchronous derivative spectrofluorimetry." Brazilian Journal of Pharmaceutical Sciences 50, no. 2 (2014): 329–36. http://dx.doi.org/10.1590/s1984-82502014000200012.

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The dissolution process is considered an important in vitro tool to evaluate product quality and drug release behavior. Single dissolution methods for the analysis of combined dosage forms are preferred to simplify quality control testing. The objective of the present work was to develop and validate a single dissolution test for a telmisartan (TEL) and amlodipine besylate (AML) combined tablet dosage form. The sink conditions, stability and specificity of both drugs in different dissolution media were tested to choose a discriminatory dissolution method, which uses an USP type-II apparatus wi

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Mohammed Abdulzahra Hussein and Mohanad Naji Sahib. "The predictive power of biphasic dissolution approach using Class IV model drug." Al Mustansiriyah Journal of Pharmaceutical Sciences 23, no. 2 (2023): 221–30. http://dx.doi.org/10.32947/ajps.v23i2.1024.

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This study was aimed to evaluate biphasic dissolution system and its applicability to discriminate between different formulas. Two different tablet formulas of furosemide were prepared using dry compression (F1) and wet granulation (F2). The prepared formulas were evaluated for hardness, friability and disintegration. Thereafter, monophasic and biphasic dissolution systems were used to compare the dissolution profiles of the prepared formulas with a commercially available tablet. The results of the physical properties of the prepared tablets were within acceptable values. Moreover, there

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Thèses sur le sujet "Discriminatory Dissolution"

Neves, Maria Cristiana das. "Análise Quantitativa e Qualitativa da Dissolução de uma Formulação de Ibuprofeno." Master's thesis, 2018. http://hdl.handle.net/10316/86557.

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Dissertação de Mestrado em Química apresentada à Faculdade de Ciências e Tecnologia<br>O presente projeto de mestrado foi desenvolvido nos Laboratórios Basi e teve comoobjetivo principal o desenvolvimento de um método de dissolução de supositórios contendo ibuprofeno que melhor permita discriminar entre lotes, de forma a avaliar o poder discriminatório. Para se chegar ao objetivo final foram delineados vários objetivos específicos: 1) validação de um método analítico de quantificação do ibuprofeno em ensaios de dissolução por cromatografia líquida de alta eficiência (HPLC); 2) testar o poder d

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Britz, Chantal. "The discriminatory ability of analytical quality control test methods : a comparison of test results from different international monographs of quinine sulfate tablets / Chantal Britz." Thesis, 2013. http://hdl.handle.net/10394/10709.

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Malaria is a parasitic disease claiming one million lives worldwide annually. Unfortunately, malaria-endemic countries in need of good quality medicines are also overwhelmed with counterfeit or substandard medicine. This results in treatment inefficacy, resistance towards treatment and death. Counterfeit or substandard quinine sulfate tablets are known to have infiltrated the market, however at this point in time, treatment efficacy of quinine sulfate has fortunately not yet been significantly impaired by resistance, but immediate action is required to prevent it from becoming obsolete. Valida

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Chapitres de livres sur le sujet "Discriminatory Dissolution"

Stark, P., A. Kinahan, S. Cunningham, et al. "Determination of Critical Manufacturing and Formulation Variables for a Hydrophilic Matrix Tablet Formulation Using an in Vitro Discriminatory Dissolution Method." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4684-6036-0_11.

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Farrell, C., J. Butler, P. Stark, H. Madden, and J. Devane. "The Development of a Novel in Vitro Discriminatory Dissolution Method for a Class I Drug in a Matrix Tablet Formulation." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4684-6036-0_20.

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Kulinowski, P., and P. DoroŻyŃski. "Applications of MRI to Study Controlled Drug Release Formulations: From Model Formulations Toward the Understanding of Drug Products Behavior." In Magnetic Resonance and its Applications in Drug Formulation and Delivery. Royal Society of Chemistry, 2024. http://dx.doi.org/10.1039/9781788019996-00333.

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Magnetic resonance (MR) imaging is a flexible, multimodal technique with a plethora of imaging pulse sequences and their possible modifications. The goal of the chapter is to give researchers who work in the field of drug development, manufacturing, and formulation some hints concerning the applicability of MR imaging techniques to solve technological issues. Application of MR imaging (1) can give spatio-temporal characteristics of the controlled release formulations during hydration/dissolution; (2) can help to explain of mechanisms of matrix hydration and drug dissolution; (3) can explain so

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Mandpe, Pankaj. "Development of a Discriminatory Drug Dissolution Method for Estimation of Rivaroxaban from Rivaroxaban Tablets." In Current Aspects in Pharmaceutical Research and Development Vol. 2. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/caprd/v2/4632f.

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Schervenski da Silva, Tiago Luis, Paula Fernanda Failace Antunes de Oliveira, and Augusto Jobim do Amaral. "ALGORITMOS, CAPITALISMO DE PLATAFORMA E A INCESSANTE BUSCA PELO ESTAR." In ESTUDOS DE DIREITO, DESENVOLVIMENTO E ACESSO À JUSTIÇA, Vol. II. Iberojur Science Press, 2024. https://doi.org/10.62140/tspoaa6752024.

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This paper aims to offer initial reflections on the condition of being/existing and its relationship with techniques of control and surveillance, which take on new forms due to the intimate relationship between social control, algorithms, and data, and are thus subject to constant modulation. To better understand the problem, the study seeks to explore the foundations of algorithmic governmentality, that is, the practice of immanent and distributed surveillance that extracts and preserves massive amounts of data from individuals and exerts control through subtle correlations, conditioning and

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