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Thèses sur le sujet « PIMS model »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

Schawalder, Martin. "The various levels of importance of the five structural components of the Viable System Model (VSM) at different stages of a system's S-curve development regarding improvement of its viability." St. Gallen, 2007. http://www.biblio.unisg.ch/org/biblio/edoc.nsf/wwwDisplayIdentifier/01653666002/$FILE/01653666002.pdf.

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Nguyen, Phuong. "Aplikace teorií ekonomického růstu na Irsko a komparace s jižním křídlem eurozóny (země PIGS)." Master's thesis, Vysoká škola ekonomická v Praze, 2017. http://www.nusl.cz/ntk/nusl-360681.

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The Ireland´s recovery from the crisis that broke in the Irish economy was fast comparing to other eurozone nations so-called PIIGS. Therefore, the thesis identify sources and turning points that generate the inclusive growth of the Irish economy. Economic growth comes from the accumulation of labour and capital inputs combined with improvements in the productivity of labour associated with technological progress. There are clear signals that all these factors contribute to the economy growth in Ireland. Ireland benefits from large inflows of foreign direct investment that helps to spread tech

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3

Cortezi, Matheus Vasconcellos. "Observations of the South Atlantic Subtropical Mode Water using PIES data." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/21/21135/tde-23032018-141954/.

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Subtropical mode water is a voluminous body of water in the ocean whose main feature is the homogeneity in both vertical structure and horizontal extension. The subtropical mode water (STMW) of the southwest Atlantic is formed between the months of July and October near the Brazil-Malvinas confluence and along the Brazil Current recirculation gyre. The formation region extends on the order of 3000 km zonally, from 20°W to 50°W, and 1000 km meridionally, from 30°S to 40°S, and it is typically about 170 m thick. In situ data from pressure-equipped inverted echo sounders (PIES) installed in the

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4

Russell-Lodrigue, Kasi Elizabeth. "An inhalation model of acute Q fever in guinea pigs." [College Station, Tex. : Texas A&M University, 2006. http://hdl.handle.net/1969.1/ETD-TAMU-1209.

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Sobral, Júnior Mário Alves. "Proposta de modelo para analisar desempenho do Programa de CCQ de uma empresa de eletroeletrônico do PIM." Universidade Federal do Amazonas, 2013. http://tede.ufam.edu.br/handle/tede/3556.

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Made available in DSpace on 2015-04-22T22:10:56Z (GMT). No. of bitstreams: 1 mario sobral.pdf: 1031304 bytes, checksum: 17b78abcce30773ebc357d63a1e2c07b (MD5) Previous issue date: 2013-08-06<br>The Circle of Quality Control consists on a group of employees who volunteer to support a company, whose goal is to identify, analyze and propose improvements to problems detected in work, besides focusing on professional development and improving the work environment. The company studied has increased focus on financial return of the QCC, having no tools to evaluate the attendant performances and t

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Neef, N. A. "Porcine colitis syndrome : experimental models of disease and dietary influences." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241175.

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7

Cheetham, Sonia Maria. "Pathogenesis of human norovirus in gnotobiotic pigs." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1149018306.

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Hernandez, Gabriella Veronica, Victoria Alice Smith, Morgan Coffin, et al. "Development of a Pediatric Model of Nafld in Neonatal Iberian Pigs." DigitalCommons@CalPoly, 2019. https://digitalcommons.calpoly.edu/theses/2097.

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The prevalence of non-alcoholic fatty liver disease (NAFLD) in children has increased over the past decades, creating a need for animal models that recapitulate the features of the pediatric disease. Iberian pigs have a leptin-resistant phenotype characterized by hyperleptinemia, hyperphagia, and extreme adipogenesis. We hypothesized that neonatal Iberian pigs fed a high fat high-fructose (HFF) diet will develop a pattern of liver injury resembling pediatric NAFLD. In addition, we sought to determine if a mixture of probiotics would prevent the disease. Animals were fed 1 of 4 diets containing

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9

Parikh, Sanjiv D. "Computerized Ultrasonic Raytracing Model for C-scans of Solid Steel Bridge Pins." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/37054.

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This report describes the results of computerized ultrasonic C-scanning of solid steel bridge pins using a raytrace model. The raytrace model was developed to facilitate interpretation of data obtained from an ultrasonic C-scanning system for the Virginia Transportation Research Council (VTRC). The report discusses the reasons behind the development of the raytrace model, as well as specifications of the model, the input conditions, and the data output and visualization. The model uses as input, various "boundary" conditions of the solid steel pin with reduced diameter pin ends, as well as siz

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Lopes, Carlos Romeu Montes. "Impactos ambientais da agroindústria de suínos no sudoeste de Goiás: modelo para o alcance da sustentabilidade da atividade." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/4177.

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Vijay, Ajay Kumar Optometry &amp Vision Science Faculty of Science UNSW. "Effect of antibacterial contact lenses on inflammatory responses in a guinea pig model." Awarded by:University of New South Wales, 2007. http://handle.unsw.edu.au/1959.4/35219.

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Contact Lens Acute Red Eye (CLARE) and Infiltrative Keratitis (IK) are inflammatory responses of the eye associated with extended wear of soft contact lenses. Bacterial colonization of contact lenses with Gram-negative bacteria such as Pseudomonas aeruginosa is an important risk factor for the development of these adverse responses. Strategies that control the bacterial colonization of contact lenses may help prevent the occurrence of adverse responses. This thesis aimed to develop an animal model of CLARE/IK to test this hypothesis and to test the effectiveness of contact lenses containing an

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12

Jacobson, Magdalena. "Enteric diseases in pigs from weaning to slaughter /." Uppsala : Dept. of Large Animal Clinical Sciences, Swedish Univ. of Agricultural Sciences, 2003. http://epsilon.slu.se/v158.pdf.

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Carvalho, Silmara Cardoso de. "Índice da competitividade logística do PIM - modal aéreo." Universidade Federal do Amazonas, 2013. http://tede.ufam.edu.br/handle/tede/3567.

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Made available in DSpace on 2015-04-22T22:11:03Z (GMT). No. of bitstreams: 1 Silmara de C Marambio.pdf: 1355745 bytes, checksum: 6e74333ccdb0a8a2abd7e289ab2b776d (MD5) Previous issue date: 2013-12-27<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Globalization is a reality that affects all sectors of society, economic relations have changed dramatically since the conception of this borderless world. The industries that were established only in their home country , have joined industrial clusters around the world , aiming to make their products more competitive and mee

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14

Kocher, Jacob F. "Evaluation of the novel P particle vaccine candidate against human norovirus using the gnotobiotic pig challenge model." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/71305.

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Noroviruses (NoVs) are a cause of nonbacterial acute gastroenteritis affecting all ages. NoV infections result in over 200,000 pediatric deaths in developing countries annually. Vaccine development has been hindered by the lack of cell culture systems and small animal models; thus, vaccine development has relied upon recombinant VP1 capsid proteins, such as virus-like particles (VLPs) and P particles. P particles are a novel vaccine candidate derived from expression of the VP1 protruding (P) domain, while VLPs require expression of the full-length VP1. My studies utilize a gnotobiotic (Gn) pig

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15

Camp, Nicola J. "Methods for genealogical analysis, with particular reference to Type II diabetes in the Pima." Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364310.

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16

Bainbridge, Terry Cyril. "A practical model of bronchogenic carcinoma in Camm-Hartley guinea pigs and Golden Syrian hamsters." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/25843.

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Bronchogenic carcinoma (lung cancer) is a major source of morbidity and mortality in industrialized nations. Although bronchogenic carcinoma is largely a preventable neoplasm, it will undoubtedly remain a major medical concern throughout this century, and considerable effort needs to be directed towards its early detection, establishing effective treatment, and understanding the neoplastic process. The objective of this study was to develop a practical and reliable model of localized bronchogenic carcinoma in laboratory rodents. This was done by impregnating cotton threads with the potent car

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AQUINO, Renato Machado. "Modelo matem?tico para a simula??o da produ??o de mel em munic?pios do Rio de Janeiro." Universidade Federal Rural do Rio de Janeiro, 2015. https://tede.ufrrj.br/jspui/handle/jspui/2321.

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Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2018-05-18T18:24:16Z No. of bitstreams: 1 2015 - Renato Machado Aquino.pdf: 1434016 bytes, checksum: 3679650b2f036e3b85b93c090450ba7d (MD5)<br>Made available in DSpace on 2018-05-18T18:24:16Z (GMT). No. of bitstreams: 1 2015 - Renato Machado Aquino.pdf: 1434016 bytes, checksum: 3679650b2f036e3b85b93c090450ba7d (MD5) Previous issue date: 2015-04-29<br>Brazil and Argentina amongst the world?s ten leading countries in honey exports. The two countries share in this commodity exports was about US$ 220 million dollars in 2011. Argentina is on

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18

Caliari, Giuliano Luz Pigatti. "Transformações e mapeamentos da MDA e sua implementação em três ferramentas." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/3/3141/tde-08012008-103612/.

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As transformações de modelos são um ponto vital para os enfoques de desenvolvimento dirigido por modelos, incluindo a MDA. No presente trabalho apresenta-se alguns dos conceitos da MDA relacionados a transformações de modelos. São vistos os conceitos de PIM, PSM, transformações, mapeamentos e marcas. Estes conceitos são analisados no contexto de três ferramentas MDA, a OptimalJ, a AndroMDA e a ArcStyler, para verificar se as ferramentas os implementam de acordo com a MDA. Também é analisado como e quais transformações e mapeamentos de modelos estão sendo implementados pelas ferramentas, atravé

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19

Oliver, Gina. "Gene expression profiling in pigs : a comparison between social and maternal aggression models." Thesis, Anglia Ruskin University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490300.

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20

MacKenzie, Katrin. "Quantifying selection for resistance to infectious diseases in pigs using genetic epidemiological models." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/12516.

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The purpose of this thesis is to quantify the effect of selection for disease resistance on the epidemiology of microparasitic infection in pigs, combining quantitative genetics and epidemiology using computer simulation. Two methods of selection are investigated: continuous selection at an arbitrary rate of progress and resistance gene introgression Selection is simulated on a 500 sow farrow-to-finish farm with selection taking place in the sires used to provide semen. A discrete-time model is introduced which expands that of De Jong (1994) allowing reduced susceptibility to infection to be i

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21

Lizer, Joshua Thomas. "Development of a conventional pig model for Clostridium difficile infection and associated disease in neonatal pigs." [Ames, Iowa : Iowa State University], 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1476320.

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22

Schwerdtle, Hartwig. "Prozessintegriertes Management - PIM : ein Modell für effizientes Qualitäts-, Umwelt- und Arbeitsschutzmanagement /." Berlin : Springer, 1999. http://aleph.unisg.ch/hsgscan/hm00006710.pdf.

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23

Ramesh, Ashwin Kumar. "Study of enteric virus infection and parenteral vaccines in the gnotobiotic pig model." Diss., Virginia Tech, 2020. http://hdl.handle.net/10919/104356.

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Human rotavirus (HRV) and human norovirus (HuNoV) are the most common causative agents of acute gastroenteritis- (AGE) related morbidity and mortality around the world. Gnotobiotic (Gn) pigs are the ideal large-animal model that allows for accurate, and precise, preclinical evaluation of vaccine efficacy. Similarities in gastrointestinal anatomy, physiology, and immune system allows for direct translation of results from Gn pigs to humans. Commercially available HRV vaccines perform significantly poorer in low- and middle- income countries as compared with developed countries. Non-replicating

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24

McCourt, Shannon M. "Lactogenesis Induction in Transgenic Virgin Pigs as a Model for Identifying Transgene Expression and Recombinant Protein Production." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/46507.

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The porcine mammary gland can be used for the production of recombinant proteins by directing a transgene to the mammary gland with a milk protein gene promoter. In order to determine whether or not the protein will be expressed, the animals must be maintained at least through their first lactation. An experiment was performed to determine if hormonal induction of lactogenesis in transgenic virgin pigs could be used as a method for identifying those gilts that are likely to express the recombinant protein during a natural lactation. Mammary development and lactogenesis were induced by admin

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25

CINTI, ALESSANDRO. "Study of the role of protective genes against inflammatory stimuli in experimental in vitro and in vivo models." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50968.

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During my PhD program I addressed my attention on the characterization and possible regulation of the inflammatory response, induced by pro-inflammatory cytokines in vitro, and hypercholesterolemic diet in vivo. Thanks to the chance I had, to be primary involved in different projects in my PhD program, the study presented here embraces two aspects that at first may appear different, but share the property to act on the tissue as an “insult” to which the cells have to react. On one side, in our laboratory we performed in vitro studies characterizing the protective effects, against inflammatory

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Campideli, Thaiza da Silva. "Sensibilidade de valores gen?ticos de til?pias do Nilo, variedade tailandesa, aos n?veis de lisina digest?vel das dietas." UFVJM, 2017. http://acervo.ufvjm.edu.br/jspui/handle/1/1567.

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Incluir como ag?ncias financiadoras: Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG), Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES), Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq).<br>Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2018-01-05T18:15:19Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) thaiza_silva_campideli.pdf: 3972827 bytes, checksum: d46dcbd4e39c922c90034d3992c8ad54 (MD5)<br>Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.e

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Procházka, Tomáš. "Modelování protokolu PIM-SM v prostředí OMNeT++." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2013. http://www.nusl.cz/ntk/nusl-236166.

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In this master's thesis I deal with modelling and simulating of multicast routing protocol PIM Sparse Mode in OMNeT++. I also describe basic information about multicast, protocol PIM-SM, its configuration and multicast data streams visualization in computer networks. The thesis is especially focused on design and implementation of PIM-SM in OMNeT++ and extension of ANSAINET library.

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Plym, Forshell Linus. "Assessment of therapeutic targets in experimental models of Myc-induced lymphoma." Doctoral thesis, Umeå universitet, Institutionen för molekylärbiologi (Teknisk-naturvetenskaplig fakultet), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-46534.

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The Myc transcription factor activates expression of genes that promote cellular functions such as proliferation and cell growth. The deregulated Myc expression, characteristic for the tumor cell, also activates apoptosis, which selects for additional genetic changes deactivating the induced cell death. However, the continuous overexpression of Myc can also be a liability for a tumor, which can be taken advantage of in cancer treatment. In Paper I, we describe a new way of using the DNA methyltransferase inhibitor Decitabine, in treating Myc overexpressing tumors. We show that Decitabine trea

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Iguchi, Kota. "Chronological profiling of plasma native peptides after hepatectomy in pigs: Toward the discovery of human biomarkers for liver regeneration." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225465.

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Vanelli, A. "ISOLATION, CHARACTERIZATION AND DIFFERENTIATION POTENTIAL OF CARDIAC PROGENITOR CELLS IN ADULT PIGS." Doctoral thesis, Università degli Studi di Milano, 2011. http://hdl.handle.net/2434/169553.

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Cardiac progenitor cells have been recently identified in the post-natal heart. However, the experiments carried out so far were predominantly performed on mice and humans. Considering the potential future application of these cells for human cell therapy, we propose the pig as an intermediate preclinical model, due to the morphological and functional affinity of the porcine species with the human. Pig adult cardiac progenitors were isolated from explants of adult pig hearts and cultured in complete DMEM medium. Cells were analyzed for their expansion ability and for the expression of surface

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Djokic, Vitomir. "Prevalence and risk factors for toxoplasmosis in pigs and characterization of natural evolution of infection in a pig model." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066097/document.

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Dans le phylum des Apicomplexa le parasite Toxoplasma gondii est adapté à l'infection de tous les animaux à sang chaud y compris l'homme. L'infection se produit après la naissance par l'ingestion de kystes i) présents dans les muscles des animaux infectés, ou ii) des formes résistantes de l'environnement – les oocystes contaminants l'eau, les fruits et légumes, les coquillages. La maladie est généralement bénigne, mais l'infection peut avoir des conséquences graves pour le développement du fœtus dans le cas de l'infection maternelle pendant la grossesse et chez les individus immunodéprimés.Hor

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Djokic, Vitomir. "Prevalence and risk factors for toxoplasmosis in pigs and characterization of natural evolution of infection in a pig model." Electronic Thesis or Diss., Paris 6, 2016. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2016PA066097.pdf.

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Dans le phylum des Apicomplexa le parasite Toxoplasma gondii est adapté à l'infection de tous les animaux à sang chaud y compris l'homme. L'infection se produit après la naissance par l'ingestion de kystes i) présents dans les muscles des animaux infectés, ou ii) des formes résistantes de l'environnement – les oocystes contaminants l'eau, les fruits et légumes, les coquillages. La maladie est généralement bénigne, mais l'infection peut avoir des conséquences graves pour le développement du fœtus dans le cas de l'infection maternelle pendant la grossesse et chez les individus immunodéprimés.Hor

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SOUZA, ROBSON DE OLIVEIRA. "EXPERIMENTAL VALIDATION OF MODELS FOR PREDICTING THE FORCES FOR REMOVING WAX DEPOSITS IN PIPELINES USING PIGS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2005. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=7358@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>Pigs ainda são a ferramenta mais utilizada pela indústria para remover depósitos de parafina em linhas submarinas de petróleo. A passagem de Pigs é considerada uma operação de risco, pois existe a possibilidade do gradiente de pressão disponível para deslocar o Pig não ser suficiente para vencer as forças de contato entre o Pig e a parede do tubo e as forças necessárias para remoção do depósito de parafina. Neste trabalho realizou-se um estudo experimental visando o levantamento de dados de laboratório sobre as forças de contato Pig-

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Murgado, Amaury. "The Bay of Pigs Invasion: A Case Study in Foreign Policy Decision-Making." Master's thesis, Orlando, Fla. : University of Central Florida, 2009. http://purl.fcla.edu/fcla/etd/CFE0002522.

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Nascimento, Joel Castro do. "Avaliação dos resultados da análise de tomada de decisão em projetos de infraestrutura de transporte de carga por meio do AHP Fuzzy." Universidade Federal do Amazonas, 2012. http://tede.ufam.edu.br/handle/tede/3550.

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Made available in DSpace on 2015-04-22T22:10:52Z (GMT). No. of bitstreams: 1 joel.pdf: 1373421 bytes, checksum: 9493a0d93e7c7b57b98f34a2d9660992 (MD5) Previous issue date: 2012-04-13<br>Fundação de Amparo à Pesquisa do Estado do Amazonas<br>The transport infrastructure is essential to the socioeconomic development of a nation. In Brazil, the infrastructure is inefficient and does not meet the potential growth of its different regions. In the state of Amazonas, the situation is critical, because the peculiar characteristics of their climatic and environmental conditions hamper regional mobi

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Pelayo, García-Bustelo Begoña Cristina. "TALISMAN: desarrollo ágil de Software con Arquitecturas Dirigidas por Modelos." Doctoral thesis, Universidad de Oviedo, 2007. http://hdl.handle.net/10803/35683.

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La especificación Model Driven Architecture (MDA), es una especialización del desarrollo dirigido por modelos que separa la lógica del negocio del software y las plataformas tecnológicas. Para ello MDA define tres tipos de modelos. Los CIM, Computation Independent Model, asociados al dominio del negocio, los PIM, Platform Independent Model, asociados a modelos abstractos del software, y los PSM, Platform Specific Model, relacionados con modelos de software específicos de plataformas tecnológicas. Sin embargo MDA no detalla cómo deben ser los modelos CIM y tampoco describe cómo deben ser transf

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Mokrani, Cyril. "Impacts de vagues déferlantes sur un obstacle vertical. Modèle théorique et calcul numérique des pics de pression." Thesis, Pau, 2012. http://www.theses.fr/2012PAUU3004/document.

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Cette thèse étudie numériquement l'impact d'une onde déferlante à l'échelle de la vague. Dans un premier temps, le phénomène de percussion présent sur de faibles durées est décrit dans deux cas de lâcher de barrage. Les résultats montrent que la réduction du pas d'espace induit des changements locaux dans le profil d'interface avant l'impact. Ces changements influencent fortement les pics de pression, rendant ainsi leur estimation impossible. L'influence de lagéométrie locale de l'interface est théoriquement étudiée sur le cas d'un jet triangulaire. En développant deux lois semi-empiriques, no

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Oliveira, Filho João Xavier de. "Estudo da patogenia e desenvolvimento de métodos de Diagnóstico da pasteurelose pneumônica em suínos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/96985.

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Pasteurella multocida é um dos principais patógenos envolvidos nas broncopneumonias infecciosas em suínos. Apesar de ser considerada agente secundário à pneumonia enzoótica causada pelo Mycoplasma hyopneumoniae e por agentes virais como o vírus da influenza suína, há evidências do seu envolvimento como agente primário. Neste contexto, o primeiro estudo desenvolvido teve como objetivo desenvolver um método de reprodução experimental de pneumonia por P. multocida A cepa 11246 em suínos infectados com diferentes concentrações de inóculo. Um segundo estudo foi desenvolvido com o objetivo de demons

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Roan, Shii-Wen. "Bio-economic models for the simulation of the production and management of the growing pigs and sows." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/14290.

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This thesis was made to create a new version of the Edinburgh Model Pig computer program, to build a factorial computer model of nutrient utilisation by the breeding sow, to validate the Model Pig and the Model Sow, to expand the modelling function to economic aspects and to link with other packages relating to the feeding and management of pigs, and thereby to build a bio-economic model package of pig production systems. Chapter 1 describes the background of the use of models in pig science and production and indicates the purpose of the present work. Chapter 2 introduces the concepts of comp

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Nascimento, Wanessa da Costa, and 92-98403-5353. "Parque Eco-Industrial: uma análise de modelo conceitual para o Polo Industrial de Manaus - PIM." Universidade Federal do Amazonas, 2017. http://tede.ufam.edu.br/handle/tede/6035.

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Kemper, Daniella Aparecida Godoi. "Efeitos do sildenafil em modelo experimental de endotoxemia em suínos." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-15032016-120616/.

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INTRODUÇÃO: Apesar de todos os esforços, as taxas de mortalidade no choque séptico ainda são altas, e entre as diversas complicações deste quadro, a hipertensão pulmonar é considerada um fator agravante. O sildenafil é um fármaco com efeito vasodilatador arterial pulmonar que atua através da inibição da fosfodiesterase 5, aumentando o GMPcíclico e promovendo relaxamento da musculatura lisa. OBJETIVO: Avaliar se a administração de sildenafil atenua as alterações hemodinâmicas ocasionadas pelo choque endotoxêmico, bem como os parâmetros de ventilação e oxigenação em modelo experimental de endoto

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Castrillon, Jenny Paola Bravo. "An?lise wavelet e modelo de manchas em curvas de luz estelares dos telesc?pios espaciais Kepler e CoRoT." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br/handle/123456789/20102.

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Howell, Peter Mark. "Disruptive game design : a commercial design and development methodology for supporting player cognitive engagement in digital games." Thesis, University of Portsmouth, 2015. https://researchportal.port.ac.uk/portal/en/theses/disruptive-game-design(cac71c4d-74b4-491b-a7e2-cb28e1fac235).html.

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First-person games often support the player’s gradual accretion of knowledge of the game’s rules during gameplay. They thus focus on challenging and developing performative skills, which in turn supports the player in attaining feelings of achievement and skills mastery. However, an alternative disruptive game design approach is proposed as an approach that encourages players to engage in higher-order thinking, in addition to performative challenges. This requires players to cognitively engage with the game at a deeper level. This stems from the player’s expectations of game rules and behaviou

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Sant\'Ana, Alex Jader. "Avaliação da responsividade cardiovascular por meio da variação de pulso com diferentes fluídos em modelo experimental de hemodiluição normovolêmica aguda." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-23032010-104404/.

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Introdução: A variação da pressão de pulso (PP) tem se mostrado ser uma ferramenta indicadora da responsividade à terapia de fluídos em estudos clínicos e experimentais. Entretanto, esses parâmetros ainda não foram adequadamente estudados em situações de variação aguda da viscosidade sanguínea, como ocorre durante hemodiluição normovolêmica aguda (HNA). O propósito desse estudo é comparar o comportamento do PP em modelo experimental de HNA em suínos com reposição volêmica com solução salina ou colóide. Métodos: Vinte e um suínos de peso médio de 32kg foram anestesiados e randomizados em três g

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Klinger, Bernhard [Verfasser], and Eckhard [Akademischer Betreuer] Wolf. "Efficiency and safety of gene editing in pigs: Evaluated in an experimental and in a disease relevant model / Bernhard Klinger ; Betreuer: Eckhard Wolf." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2021. http://nbn-resolving.de/urn:nbn:de:bvb:19-285818.

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Jesus, Sâmia Regina Picanço de. "Análise de competitividade dos custos logísticos do modal aéreo: estudo no setor produtor de relógios do PIM." Universidade Federal do Amazonas, 2014. http://tede.ufam.edu.br/handle/tede/4076.

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Nogueira, Fernanda Alves, and 92-99264-0099. "Proposta de modelo de manufatura enxuta nas operações de serviço de uma empresa de bebidas do PIM." Universidade Federal do Amazonas, 2011. http://tede.ufam.edu.br/handle/tede/6203.

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Tijero, Esteve Verónica. "Regulación hormonal del crecimiento, maduración y sobremaduración en un modelo de fruto no climatérico: Prunus avium L var. Pime Giant." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668260.

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Las cerezas (Prunus avium L.) son frutos muy apreciados por el consumidor, alrededor del mundo, debido a sus características visuales y organolépticas. Como un fruto carnoso con hueso no climatérico, los cambios bioquímicos y físicos que ocurren durante su crecimiento, maduración y sobremaduración están regulados por las hormonas. Para comprender mejor la compleja interacción entre algunas fitohormonas durante estos procesos y cómo afectan a los parámetros de calidad, las cerezas se recolectaron de una finca comercial en diferentes etapas del desarrollo en árbol y, además, durante el período p

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Deng, Weikun. "Amélioration du diagnostic et du pronostic dans des conditions de données rares et de connaissances limitées par l'apprentissage automatique informé par la physique et auto-supervisé." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSEP107.

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Cette thèse aborde le défi des « données éparses et des connaissances rares » dans le développement d’un modèle générique de pronostic et de gestion de la santé (PHM). Elle met en lumière l'efficacité des modèles hybrides combinant la modélisation basée sur la physique (PBM) et l'apprentissage automatique (ML), notamment l'apprentissage automatique informé par la physique (PIML) et l'apprentissage auto-supervisé (SSL) pour apprendre à partir de données non étiquetées. La thèse apporte ainsi des contributions significatives aux théories PIML et SSL et à leurs applications pratiques dans le PHM.

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Nunes, Paula Santos. "Efeito de filmes de colágeno contendo ácido úsnico em queimaduras utilizando modelo suíno." Universidade Federal de Sergipe, 2013. https://ri.ufs.br/handle/riufs/3555.

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The search for products to treat wounds caused by burns is mainly increasing. Several products are developed and marketed with the purpose of act accelerating the scar dynamics, such as topical agents, solutions, grafts, and interactive dressings and biofilms. The gelatin has been one of the most studied materials for this purpose because it shows cellular architecture suitable to act as support in the construction of new tissues as well, allows the incorporation of active substances in its protein structure. The usnic acid (UA), a secondary metabolite of lichens, has shown promising biologi

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