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Littérature scientifique sur le sujet « Sustained Release Matrix Tablet »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Sustained Release Matrix Tablet"

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Nooreen, Hari kiriti varma G, and Vijayakuchana. "Formulation and in vitro evaluation of sustained release matrix tablets of Rimopride Citrate Dihydrate." Frontier Journal of Pharmaceutical Sciences and Research 7, no. 1 (2024): 1–5. https://doi.org/10.5281/zenodo.10575985.

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Drugs are most frequently administered by oral route. Although a few drugs taken orally are intended to be dissolved in the mouth, nearly all drugs taken orally are swallowed. A few drugs such as antacids are swallowed for their local action in the gastrointestinal tracts. Hence the above study demonstrated that combination of HPMC K4M and HPMC K15M can be used to formulate sustained release matrix tablets of Rimopride Citrate Dihydrate. This can sustain the drug release up to 24 hours as per standard dissolution profile. This can be expected to reduce the frequency of administration and decre

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Rajesh, Kuma, and Sharma Vijay. "A Review on Sustained Release Matrix Tablet." International Journal of Current Pharmaceutical Review and Research 15, no. 04 (2023): 205–20. https://doi.org/10.5281/zenodo.12635940.

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AbstractThe objective of the study was to explore the objectives, advantages and disadvantages ofsustained release matrix tablet. Different types of sustained release matrix tablet have beenexplained briefly along with various types of polymers that are used during the formulation.Various preparation methods are discussed here. There are certain physicochemical factorsand biological factors which affect the release of drug from the matrix are also discussedbriefly. These matrix tablets also have to go through many evaluation tests like thickness,hardness of tablet, friability, weight variation

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Bhowmick, Argha, Arup Manna, Sanat Kumar Mandal, et al. "Formulation Development, Evaluation and Statistical Optimization of the Release Rate of Oral Sustained Release Matrix Tablet of Aceclofena." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 15, no. 4 (2022): 6026–33. http://dx.doi.org/10.37285/ijpsn.2022.15.4.2.

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Aim: This work aimed to develop a sustained released hydrophilic matrix tablet of Aceclofenac for better therapeutic action.  Background: Conventional dosage form didn't provide the desired level of drug release. Even many-marketed sustained-release tablets didn't always meet the satisfactory level of drug release. It was a challenging job for pharmaceutical scientists to develop a well-sustained release formulation. Keeping this perspective in mind a robust sustained release formulation was designed, developed and optimized with nontoxic, inert viscoelastic, semisynthetic polymers which

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K., Rekha Rani* Y. Navya Reddy R. Mohana Priya. "FORMULATION AND EVALUATION OF SUSTAINED RELEASE DOSAGE FORM OF KETOPROFEN." indo American Journal of Pharmaceutical Sciences 04, no. 05 (2017): 1384–90. https://doi.org/10.5281/zenodo.804916.

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Sustained release Ketoprofen matrix tablets were prepared by direct compression method. The nature of the polymer influences the physical and release characteristics of the matrix tablet. The hydrophobic polymer, Ethyl cellulose has retarded the drug release from the tablet and the hydrophilic polymer, HPMC (15 cps) has release the drug. While making the combination of both hydrophilic and hydrophobic polymers i.e HPMC and Ethylcellulose with optimized ratio (F7) leads to sustained release of drug from matrix tablet for 12 hours was observed Key words: Ketoprofen, HPMC (15 cps), Ethyl cellulos

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Kanke, Pralhad K., Pankaj Sawant, Ajit Jadhav, and Md Rageeb Md Usman. "A REVIEW ON DISINTEGRATION CONTROL MATRIX TABLETS." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 19–22. http://dx.doi.org/10.22270/jddt.v8i5.1852.

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A number of sustained release formulations are available in the market which successfully sustained the drug release over a prolonged period of time by different mechanisms. The new approach for sustaining the drug release is disintegration control matrix tablet which sustained the drug release up to 24hrs by controlling the disintegration rate of tablet. Disintegration control matrix tablet (DCMT) mainly forms the granules containing drug and disintegrating agent such as low substituted hydroxyl propyl cellulose by various methods such as solid dispersion technique. The sustained release of d

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Das, Urmi, and Mohammad Salim Hossain. "Effects of release modifier on Carvedilol release from Kollidon SR based matrix." International Current Pharmaceutical Journal 1, no. 8 (2012): 186–92. http://dx.doi.org/10.3329/icpj.v1i8.11248.

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Sustained release Carvedilol matrix tablets constituting Kollidon SR were developed in this study in an attempt to investigate the effect of release modifiers on the release profile of Carvedilol from matrix. Three matrix tablet formulations were prepared by direct compression of Kollidon SR in combination with release modifier (HPMC and Microcrystalline Cellulose) and magnesium stearate. Tablets containing only Kollidon SR with the active ingredient demonstrated a rapid rate of drug release. Incorporation of HPMC in the matrix tablet prolonged the release of drug but incorporation of Microcry

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Dr., N. Sandeepthi *and Dr. L. Satyanarayana. "FORMULATION AND EVALUATION OF NAPROXEN SUSTAINED RELEASE MATRIX TABLET." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1498–510. https://doi.org/10.5281/zenodo.1204477.

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The present investigation is concerned with development and evaluation of Sustained release matrix tablets containing Naproxen using the hydrophilic polymer hydroxy propyl methyl cellulose (HPMC K100M & HPMC K4M).Preformulation study was done initially which include characterization of polymers, drug identification, FTIR compatibility and result directed for the further course of formulation. The tablets were prepared by direct compression method and evaluation done. Tablets were compressed by tablet compression machine (Karnavati Rimek Mini press1)and evaluated with different parameters l

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Singh, Neha, Durga Pandey, Nilesh Jain, and Surendra Jain. "Formulation and In Vitro Evaluation of Bilayer Tablets of Lansoprazole and Amoxycillin Trihydrate for the Treatment of Peptic Ulcer." Journal of Drug Delivery and Therapeutics 11, no. 1 (2021): 23–31. http://dx.doi.org/10.22270/jddt.v11i1.4481.

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The present work involves the formulation development, optimization and In-vitro evaluation of bilayer tablet containing Lansoprazole in the immediate release layer and Amoxycillin in the sustained release layer, using sodium starch glycolate as a super disintegrant for the immediate release layer and the hydrophilic matrix HPMC K100M, hydrophobic matrix Ethyl cellulose are used in the sustained release layer. Bilayer tablet showed as initial burst effect to provide dose of immediate release layer Lansoprazole to control the acid secretion level and the sustained release of Amoxycillin for 24

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Pralhad, Kanke. "DEVELOPMENT OF DISINTEGRATION CONTROL MATRIX TABLETS OF FEBUXOSTAT." Asian Journal of Pharmaceutical Research and Development 6, no. 4 (2018): 12–20. http://dx.doi.org/10.22270/ajprd.v6i4.392.

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Disintegration control matrix tablet (DCMT) is a new approach for poorly water soluble drugs which successfully sustain the release up to 24hrs by controlling the disintegration rate of tablet. DCMT mainly forms the granules containing drug febuxostat and disintegrant sodium alginate which controls the release of febuxostat by controlling the rate of disintegration in wax coating plays an important role. The sustained release of drug is maintained by increasing the wax coating or decreasing the amount of disintegrant. The release of drug from tablet is uniform throughout till all the drug rele

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Das, Urmi, and Mohammad Salim Hossain. "Effects of release modifier on Carvedilol release from Kollidon SR based matrix." International Current Pharmaceutical Journal 1, no. 8 (2012): 186. http://dx.doi.org/10.3329/icpj.v1i8.11095.

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<p>Sustained release Carvedilol matrix tablets constituting Kollidon SR were developed in this study in an attempt to investigate the effect of release modifiers on the release profile of Carvedilol from matrix. Three matrix tablet formulations were prepared by direct compression of Kollidon SR in combination with release modifier (HPMC and Microcrystalline Cellulose) and magnesium stearate. Tablets containing only Kollidon SR with the active ingredient demonstrated a rapid rate of drug release. Incorporation of HPMC in the matrix tablet prolonged the release of drug but incorporation of

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Thèses sur le sujet "Sustained Release Matrix Tablet"

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Hodsdon, Alison Claire. "Xanthan gum and sodium alginate as sustained-release carriers in hydrophilic matrix tablets." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259859.

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Gallardo, Alvarez Diego. "Manufacturing of matrix tablets by combining countercharged poly(meth)acrylate polymers to provide sustained release of highly soluble drugs." Göttingen Cuvillier, 2009. http://d-nb.info/993590594/04.

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Lee, Jobina J. N. "Investigations into sustained-release hydrophobic matrix pellet formulations." Thesis, University of Strathclyde, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275167.

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Kanematsu, Akihiro. "Bladder regeneration by bladder acellular matrix combined with sustained release of exogenous growth factor." Kyoto University, 2004. http://hdl.handle.net/2433/147452.

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Draganoiu, Elena Simona. "Evaluation Of Kollidon® SR for Ph-Independent Extended Release Matrix Systems." University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1054756192.

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RAJBHANDARI, SANGITA. "THE EFFECTS OF POLYMER BLENDS ON THE RELEASE OF PROPRANOLOL HYDROCHLORIDE." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1005161908.

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TILLOTSON, JOHN KING. "DEVELOPMENT AND EVALUATION OF EXTENDED-RELEASE BUMETANIDE TABLETS." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1085067185.

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Pather, Sathasivan Indiran. "An investigation of the production of non-coated sustained release beads by extrusion and Spheronization." University of the Western Cape, 1995. http://hdl.handle.net/11394/8457.

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Doctor Pharmaceuticae - DPharm<br>The popularity and increasing complexity of sustained release dosage forms has resulted in increased costs to the patient. One approach to achieve cheaper, yet effective, sustained release medication is through the simplification of production processes. Matrix tablets have been used to sustain the release of numerous drugs and are cheap to prepare. Since they are single-unit dosage forms, however, they display less predictable transit through the gastrointestinal tract. Hence, they provide less reliable blood levels of the drug in comparison with multi partic

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Elgaied-Lamouchi, Dhouha. "Découverte de nouveaux excipients pharmaceutiques à base d'amidons modifiés pour une libération prolongée d'une substance active." Thesis, Lille, 2020. https://pepite-depot.univ-lille.fr/.

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Les comprimés matriciels hydrophiles sont fréquemment utilisés pour contrôler la libération d’actif dans les formes galéniques à usage oral. Les amidons représentent un choix intéressant pour cette application. En effet, ce sont des matériaux biocompatibles, biodégradables et disponibles à partir de différentes sources végétales. En plus des amidons natifs, les amidons modifiés (AM) ont été beaucoup étudiés pour la formulation des comprimés matriciels à libération prolongée. Les modifications physico-chimiques peuvent être ajustées de manière à correspondre aux propriétés souhaitées pour une a

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Tolia, Gaurav. "Use of Silicone Adhesive for Improving Oral Controlled Delivery." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1521190743860228.

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Livres sur le sujet "Sustained Release Matrix Tablet"

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Bhadra, Subrata. Nitroglycerin Sustained Release Tablet. Formulation Design and Evaluation. GRIN Verlag GmbH, 2013.

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Chapitres de livres sur le sujet "Sustained Release Matrix Tablet"

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Awate, Pravin B., Mahesh K. Gupta, Dipak P. Kardile, Vishwas C. Bhagat, and Rajkumar V. Shete. "Design, In Vitro Evaluation of Sustained Release Matrix Tablet of Enalapril Maleate Employing Natural Polymer-Olibanum Gum and Its Resin Component." In Techno-Societal 2022. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-34648-4_47.

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Ulmius, J., Z. G. Wagner, O. Borgå, and P. Wollmer. "Simultaneous Pharmacokinetic and in vivo Gamma Scintigraphic Monitoring in the Development of an Enprofylline-Sustained Release Tablet." In Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse. Vieweg+Teubner Verlag, 1987. http://dx.doi.org/10.1007/978-3-322-91091-2_3.

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Deshpande, A. H., and D. D. Wasule. "Design and Evaluation of Gastroretentive Ranitidine HCL Sustained Release Bilayer Tablet Using Wax Matrix: A Recent Study." In Highlights on Medicine and Medical Research Vol. 6. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/hmmr/v6/2373e.

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Ram, Darshit, Santosh Kirtane, Rukhshar Khilji, Priyanka Miniya, and Jagruti Bheda. "Sustained Release Matrix Tablet of Cisapride Drug to Treats Heartburn Caused by Gastroesophageal Reflux Disease (Gerd): A Detail Study Including Formulation, Evaluation and Optimization Aspects." In Novel Aspects on Pharmaceutical Research Vol. 8. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/napr/v8/6129b.

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Chandra, S. Nigama, A. Anka Rao, and Amareswarapu V. Surendra. "Formulation and Evaluation of Minocycline Using Multiple Polymers." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00621.

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The present study was aimed at formulating and evaluating of controlled release tablets of Minocycline HCl using different polymers (guar gum, Xanthun gum and HPMC K100) at different proportions. The formulated controlled release tablets were evaluated for organoleptic properties and in vitro dissolution rate and then compared for optimum drug releasing formulation. The results of the in vitro drug release showed that the formulation containing Xanthun gum (1:1.5) has a zero-order drug release over a period of 24 h. In case of formulations containing guar gum and HPMCK100 the release of drug w

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Latha, S. Madhavi, and P. Bharghava Bhushan. "Statistical Optimization and in Vitro Evaluation of Nizatidine Floating Tablets." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00586.

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Nizatidine is a histamine (H2) receptor antagonist that is indicated in the management of Gastric Esophageal Reflux Disorder, Peptic Ulcer Disease, gastric and duodenal ulcer. The bioavailabilty of Nizatidine is around 70% and the drug suffers from low permeability issues due to its hydrophilic nature. The aim of this work was to formulate and develop non effervescent floating matrix tablets of Nizatidine to increase the bioavailability of the drug by increasing gastric residence time. NEGFMT of Nizatidine were prepared using Glyceryl Laurate (GL), lactose, aerosol and magnesium stearate. 32 f

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Mariette, B., M. Vert, and J. Coudane. "STEREOCOPOLYMERS FOR PARENTERAL SUSTAINED-RELEASE OF PEPTIDES: RELEASE OF GRF29NH2 FROM A PLA/GA MATRIX." In Advances in Drug Delivery Systems, 6. Elsevier, 1994. http://dx.doi.org/10.1016/b978-0-444-82027-3.50045-6.

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Chandel, Arvind Kumar Singh. "Devices for Controlled Release Advancements and Effectiveness." In Advances in Medical Technologies and Clinical Practice. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-4969-7.ch005.

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The term control release means the release of the molecules from any reservoir in very precise and constant amounts and following zero-order or near-to-zero-order release kinetics. This type of formulation and device has a huge market over the medical world. The basic foundation of sustained release drug delivery system enhances the biopharmaceutical and pharmacodynamics pharmacokinetic properties of a drug in such a way that its usefulness is exploited, side-effects are reduced, and cure of the disease is attained easily. The international controlled-release drug delivery technology market ha

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Davis, Mellar P. "Oxycodone." In Opioids in Cancer Pain. Oxford University PressOxford, 2005. http://dx.doi.org/10.1093/oso/9780198529439.003.0010.

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Abstract Oxycodone (14-hydroxy-7,8-di-hydrocodeinone) is a semisynthetic thebaine derivative that has been in clinical use since 1917. Oxycodone was originally formulated with non-steroidal anti-inflammatory agents. In 1981 oxycodone became available in the USA as a single agent and, by 1996, a sustained-release (SR) double matrix product became commercially available. The total dose of oxycodone was limited by the non-steroidal anti-inflammatory drug in the original formulation and, as a result, oxycodone classified as a step II or weak opioid. The availability of immediate release oxycodone

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Chen, Yashu, Hongjian Chen, Qianchun Deng, Long Chen, and David Julian McClements. "Lipophilic Nutraceuticals." In Bioactive Delivery Systems for Lipophilic Nutraceuticals. The Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781839165566-00012.

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Nutraceuticals are considered as components originating from foods, which are publicized to have health promoting effects beyond normal nutritional function due to their specific molecular structures. Certain therapeutic claims still lack further validation using controlled human trials or other long-term efficacy tests, which needs further research. Lipophilic nutraceuticals, which have poor water solubility, instability, etc., reveal the challenges of encapsulating them into the food matrix with improved bioavailability. Several kinds of delivery systems with delicate design can achieve cont

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Actes de conférences sur le sujet "Sustained Release Matrix Tablet"

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Lefnaoui, Sonia, Samia Rebouh, Mounir Bouhedda, and M. Madiha Yahoum. "ANN Optimization Using Ant Colony Algorithm for Predicting the Valsartan Sustained Release from Polyelectrolyte Complexes Matrix Tablets." In 2019 International Conference on Applied Automation and Industrial Diagnostics (ICAAID). IEEE, 2019. http://dx.doi.org/10.1109/icaaid.2019.8934995.

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Surini, Silvia, Dina Risma Wati, and Rezi Riadhi Syahdi. "Preparation and characterization of cross-linked excipient of coprocessed xanthan gum-acacia gum as matrix for sustained release tablets." In 2ND BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2017. Author(s), 2018. http://dx.doi.org/10.1063/1.5023956.

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Li, Zao-hui, and Jiao Wang. "Studies on preparation of matrine solid dispersion sustained-release tablets." In 2017 2nd International Conference on Materials Science, Machinery and Energy Engineering (MSMEE 2017). Atlantis Press, 2017. http://dx.doi.org/10.2991/msmee-17.2017.40.

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Laera, Davide, Kevin Prieur, Daniel Durox, Thierry Schuller, Sergio M. Camporeale, and Sébastien Candel. "Impact of Heat Release Distribution on the Spinning Modes of an Annular Combustor With Multiple Matrix Burners." In ASME Turbo Expo 2016: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/gt2016-56309.

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Annular combustors of aero-engines and gas turbine are often affected by thermo-acoustic combustion instabilities coupled by azimuthal modes. Previous experiments as well as theoretical and numerical investigations indicate that the coupling modes involved in this process may be standing or spinning but they provide diverse interpretations of the occurrence of these two types of oscillations. The present article reports a numerical analysis of instability coupled by a spinning mode in an annular combustor. This corresponds to experiments carried out on the MICCA test facility equipped with 16

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Stow, Simon R., and Ann P. Dowling. "Thermoacoustic Oscillations in an Annular Combustor." In ASME Turbo Expo 2001: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/2001-gt-0037.

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Lean premixed prevaporised (LPP) combustion can reduce NOx emissions from gas turbines, but often leads to combustion instability. Acoustic waves produce fluctuations in heat release, for instance by perturbing the fuel–air ratio or flame shape. These heat fluctuations will in turn generate more acoustic waves and in some situations self-sustained oscillations can result. A linear model for thermoacoustic oscillations in LPP combustors is described. A thin annular combustor is assumed and so circumferential modes are included but radial dependence is ignored. The geometry consists of straight

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Laera, Davide, Giovanni Campa, Sergio M. Camporeale, et al. "Modelling of Thermoacoustic Combustion Instabilities Phenomena: Application to an Experimental Rig for Testing Full Scale Burners." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-25273.

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This paper concerns the acoustic analysis of self–sustained thermoacoustic pressure oscillations that occur in a test rig equipped with full scale lean premixed burner. The experimental work is conducted by Ansaldo Energia and CCA (Centro Combustione Ambiente) at the Ansaldo Caldaie facility in Gioia del Colle (Italy), in cooperation with Politecnico di Bari. The test rig is characterized by a longitudinal development with two acoustic volumes, plenum and combustion chamber, coupled by the burner. The length of both chambers can be varied with continuity in order to obtain instability at diffe

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