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Letteratura scientifica selezionata sul tema "Bones – Molecular aspects"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 agosto 2024

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Articoli di riviste sul tema "Bones – Molecular aspects"

Safarova, S. S. "Pathogenetic aspects of bone metabolism in diabetes mellitus." Clinical Medicine (Russian Journal) 96, no. 8 (December 20, 2018): 707–12. http://dx.doi.org/10.18821/0023-2149-2018-96-8-707-712.

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Metabolic disorders caused by diabetes affect bone remodeling, alter the structure and reduce the strength of bone tissue, leading to the development of diabetic osteopathy. However, between diabetes mellitus (DM) type 1 and 2 there are noticeable differences in the effect on the bone structure, which is obviously due to the different cellular and molecular mechanisms of these processes. The density of bone tissue with DM typel decreases, which leads to an increase in the risk of fractures by 7 times. With DM type 2, bone mineral density is moderately elevated, which is expected to lead to a d

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Wang, Yen-Hsiang, Kuan-Chieh Lee, Wen-Chun Wei, Chung-Huang Wang, Hao-Jie Liu, Jia-Rong Hou, Tien-Chen Hsieh, et al. "Hybrid Vibration and UV Fluorescence Technology for Rapid Imaging and Guidance for Manual Removal of Fish Bones from Fish Floss." Sensors 22, no. 22 (November 20, 2022): 8978. http://dx.doi.org/10.3390/s22228978.

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The objective of the proposed human–machine cooperation (HMC) workstation is to both rapidly detect calcium-based fish bones in masses of minced fish floss and visually guide operators in approaching and removing the detected fish bones by hand based on the detection of fingernails or plastic-based gloves. Because vibration is a separation mechanism that can prevent absorption or scattering in thick fish floss for UV fluorescence detection, the design of the HMC workstation included a vibration unit together with an optical box and display screens. The system was tested with commonly used fish

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Maltsev, S. V., A. I. Safina та T. V. Mihajlova. "Гипофосфатемический рахит у детей — клинические и генетические аспекты, подходы к терапии". Practical medicine 19, № 1 (2021): 38–49. http://dx.doi.org/10.32000/2072-1757-2021-1-38-49.

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Hypophosphatemic rickets (phosphate-diabetes) is a group of diseases associated with a defect in the reabsorption of phosphates in the proximal tubules, manifested by phosphaturia, hypophosphatemia and rickets deformities of the skeleton bones. Phosphate-diabetes has different genetic variants that determine the nature and severity of clinical manifestations. X-linked dominant hypophosphatemic rickets occurs most often (in 50-90% of cases). For the diagnosis, along with clinical characteristics, an important role is assigned to the study of partial renal functions, with the determination of cl

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Kushchayev, Sergiy V., Yevgeniya S. Kushchayeva, Sri Harsha Tella, Tetiana Glushko, Karel Pacak, and Oleg M. Teytelboym. "Medullary Thyroid Carcinoma: An Update on Imaging." Journal of Thyroid Research 2019 (July 7, 2019): 1–17. http://dx.doi.org/10.1155/2019/1893047.

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Medullary thyroid carcinoma (MTC), arising from the parafollicular C cells of the thyroid, accounts for 1–2% of thyroid cancers. MTC is frequently aggressive and metastasizes to cervical and mediastinal lymph nodes, lungs, liver, and bones. Although a number of new imaging modalities for directing the management of oncologic patients evolved over the last two decades, the clinical application of these novel techniques is limited in MTC. In this article, we review the biology and molecular aspects of MTC as an important background for the use of current imaging modalities and approaches for thi

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Rice, Ritva, Aki Kallonen, Judith Cebra-Thomas, and Scott F. Gilbert. "Development of the turtle plastron, the order-defining skeletal structure." Proceedings of the National Academy of Sciences 113, no. 19 (April 25, 2016): 5317–22. http://dx.doi.org/10.1073/pnas.1600958113.

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The dorsal and ventral aspects of the turtle shell, the carapace and the plastron, are developmentally different entities. The carapace contains axial endochondral skeletal elements and exoskeletal dermal bones. The exoskeletal plastron is found in all extant and extinct species of crown turtles found to date and is synaptomorphic of the order Testudines. However, paleontological reconstructed transition forms lack a fully developed carapace and show a progression of bony elements ancestral to the plastron. To understand the evolutionary development of the plastron, it is essential to know how

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Krupa, Robert, Małgorzata Suchanecka, Andrzej Mrożek, and Katarzyna Siwek. "Features of the flexor retinaculum and its individual variation in carpal tunnel syndrome predisposition - a systematic review." Medical Journal of Cell Biology 10, no. 3 (September 1, 2022): 97–101. http://dx.doi.org/10.2478/acb-2022-0015.

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Abstract The flexor retinaculum is a structure located in the wrist, which spreads between the bones forming the carpal tunnel. Its task is to maintain the relative stabilization and protection of incorporated structures. It is also an attachment for the thenar muscles, causing biomechanical interactions in the wrist. Pathologies occurring in the carpal tunnel structures often cause pressure increase, leading to compression of the median nerve, causing carpal tunnel syndrome (CTS). This work aims to review literature knowledge and compile research outcomes in the PubMED and Google scholar data

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Abe, Shinichi, and Masahito Yamamoto. "Factors Involved in Morphogenesis in the Muscle–Tendon–Bone Complex." International Journal of Molecular Sciences 22, no. 12 (June 14, 2021): 6365. http://dx.doi.org/10.3390/ijms22126365.

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A decline in the body’s motor functions has been linked to decreased muscle mass and function in the oral cavity and throat; however, aging of the junctions of the muscles and bones has also been identified as an associated factor. Basic and clinical studies on the muscles, tendons and bones, each considered independently, have been published. In recent years, however, research has focused on muscle attachment as the muscle–tendon–bone complex from various perspectives, and there is a growing body of knowledge on SRY-box9 (Sox9) and Mohawk(Mkx), which has been identified as a common controllin

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Poryadin, G. V., A. N. Zakhvatov, and D. V. Samarina. "Pathogenetic mechanisms of postmenopausal osteoporosis formation and their relationship with cardiovascular pathology." Bulletin of Siberian Medicine 21, no. 1 (April 15, 2022): 144–51. http://dx.doi.org/10.20538/1682-0363-2022-1-144-151.

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Involutional hormonal processes characteristic of the postmenopause are accompanied by disorders that deteriorate the quality of life in the female population and lead to an increased risk of developing metabolic diseases of the bones and cardiovascular system. In modern medicine, it is extremely important to understand the pathogenesis of postmenopausal osteoporosis (PMO) in association with cardiovascular diseases, which are the main causes of mortality in the population.This review is devoted to determining the key aspects of the pathogenesis of PMO and identifying their relationships with

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Jentgen-Ceschino, Benjamin, Koen Stein, and Valentin Fischer. "Case study of radial fibrolamellar bone tissues in the outer cortex of basal sauropods." Philosophical Transactions of the Royal Society B: Biological Sciences 375, no. 1793 (January 13, 2020): 20190143. http://dx.doi.org/10.1098/rstb.2019.0143.

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The histology of sauropod long bones often appears uniform and conservative along their evolutionary tree. One of the main aspects of their bone histology is to exhibit a fibrolamellar complex in the cortex of their long bones. Here, we report another bone tissue, the radial fibrolamellar bone (RFB), in the outer cortex of the humeri of a young adult cf. Isanosaurus (Early to Late Jurassic, Thailand) and an adult Spinophorosaurus nigerensis (Early to Middle Jurassic, Niger) that do not exhibit any pathological feature on the bone surface. Its location within the cortex is unexpected, because R

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Richardson, Jo, Takanori Shono, Masataka Okabe, and Anthony Graham. "The presence of an embryonic opercular flap in amniotes." Proceedings of the Royal Society B: Biological Sciences 279, no. 1727 (June 2011): 224–29. http://dx.doi.org/10.1098/rspb.2011.0740.

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The operculum is a large flap consisting of several flat bones found on the side of the head of bony fish. During development, the opercular bones form within the second pharyngeal arch, which expands posteriorly and comes to cover the gill-bearing arches. With the evolution of the tetrapods and the assumption of a terrestrial lifestyle, it was believed that the operculum was lost. Here, we demonstrate that an embryonic operculum persists in amniotes and that its early development is homologous with that of teleosts. As in zebrafish, the second pharyngeal arch of the chick embryo grows disprop

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Tesi sul tema "Bones – Molecular aspects"

Cheng, Tak Sum. "Molecular identification and characterization of novel osteoclast V-ATPase subunits." University of Western Australia. School of Surgery and Pathology, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0068.

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[Truncated abstract] Osteoclasts are multinucleated giant cells responsible for the resorption of the mineralized bone matrix during the process of bone remodelling. During activation towards bone resorption, polarization of the osteoclast results in the formation of a unique plasma membrane, the ruffled border, the actual resorptive organelle of the osteoclast. Through this domain protons are actively pumped into the resorption lacuna creating an acidic microenvironment that favours the dissolution of the mineralized bone matrix. The polarised secretion of protons is carried out by the action

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Dai, Zhijie, and 戴志洁. "The role of sodium/myo-inositol cotransporter 1 and myo-inositol in osteogenesis and bone formation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43783533.

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Chan, Cheuk-wing Wilson, and 陳卓榮. "ER stress in the pathogenesis of osteochondrodysplasia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085192.

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Wang, Cathy Ting-Peng. "Molecular dissection of RANKL signaling pathways in osteoclasts." University of Western Australia. School of Surgery and Pathology, 2007. http://theses.library.uwa.edu.au/adt-WU2008.0037.

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[Truncated abstract] Bone remodeling is intricately regulated by osteoclast-mediated bone resorption and osteoblast-mediated bone formation. The elevation in osteoclast number and/or activity is a major hallmark of several common pathological bone disorders including post-menopausal osteoporosis, osteoarthritis, Paget's disease, and tumour-mediated osteolysis. Receptor activator of nuclear factor kappa B ligand (RANKL) is a key cytokine for osteoclast differentiation and activation. The association of RANKL to its cognate receptor, RANK, which is expressed on osteoclast precursors and mature o

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Cheng, Yin-wo, and 鄭燕和. "Molecular basis for the increased osteoblast activity in a mouse modelwith hyperostosis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B34612981.

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Lee, B. C. Bob, and 李卜駿. "Probing the molecular mechanisms of how polymorphisms in Cerberus-likeresult in low bone mineral density." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39793771.

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Cestari, Tania Mary. "Aspectos celulares, teciduais e moleculares da osteogênese ectópica e ortotópica induzida pela matriz alogênica óssea e dentinária." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/25/25142/tde-02062009-111408/.

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O objetivo do atual trabalho, foi correlacionar os eventos celulares e teciduais com a expressão das proteínas VEGF, BMP-7, RANKL e OPG durante a osteogênese ectópica e ortotópica, induzida pela matriz óssea (MO) e dentinária (MD) alogênica. Matrizes alogênicas desmineralizada em HCl a 0,6N, obtidas de fêmur e incisivo de ratos, fori implantada entre as fáscias musculares da coxa e em defeito trans-ósseo de 8mm de diâmetro nos ossos parietais. As análises radiográfica e histomorfométrica da neoformação óssea e, a imunohistoquímica e o western blotting para as proteínas VEGF, BMP, RANKL e OPG,

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Albuquerque, Dulcinéia Martins de. "Aspectos moleculares do citomegalovirus humano durante infecção ativa em pacientes submetidos ao transplante de medula ossea." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311935.

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Orientador: Sandra Cecilia Botelho Costa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-08T16:11:05Z (GMT). No. of bitstreams: 1 Albuquerque_DulcineiaMartinsde_D.pdf: 3473302 bytes, checksum: daa8d0ff76ca0850d748389f7bb2ea56 (MD5) Previous issue date: 2006<br>Resumo: O Citomegalovírus Humano (HCMV) continua sendo uma causa significante de morbidade em pacientes imunocomprometidos, especialmente em transplantados de medula óssea, e pode manifestar diversas complicações que incluem hepatite, doença gastrointestinal

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PEREIRA, Andrea de Castro. "Sítios implantáveis da maxila e mandíbula: correlação entre aspectos clínico-radiográficos e histomorfométrico-moleculares." Universidade Federal de Goiás, 2011. http://repositorio.bc.ufg.br/tede/handle/tde/1367.

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Made available in DSpace on 2014-07-29T15:21:57Z (GMT). No. of bitstreams: 1 Dissertacao_AndreaCastroPereira.pdf: 2370466 bytes, checksum: f8365afb8c90d3f08e392b9f49411d3e (MD5) Previous issue date: 2011-03-04<br>The study of bone microarchitecture and its molecular aspects may provide new information for better understanding of "bone quality". Histomorphometry is a recommended reference method for bone-dimensional analysis. At the molecular level, possible changes in the process of resorption and bone formation has not been studied in different patterns of bone "normal." Objective: To analy

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Irani, Dilshad Minocher. "Role of the surface associated material of Eikenella corrodens in bone resorption associated with periodontal disease : a research thesis submitted in fulfilment of the requirements for the degree of Master of Science in Dentistry." Title page, contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09DSM/09dsmi65.pdf.

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Libri sul tema "Bones – Molecular aspects"

Masaki, Noda, ed. Cellular and molecular biology of bone. San Diego: Academic Press, 1993.

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Hong-wen, Deng, and Liu Yao-zhong, eds. Current topics in bone biology. Singapore: World Scientific, 2005.

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Dietz, Georg. Calcium hydroxide and bone regeneration: Odontological aspects of induced osteogenesis in experiment and clinical practice. München: G. Dietz, 1998.

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R, Arnett Timothy, and Henderson Brian, eds. Methods in bone biology. London: Chapman & Hall, 1998.

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Rosen, Vicki. The cellular and molecular basis of bone formation and repair. New York: Springer, 1995.

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Cardew, Gail. The molecular basis of skeletogenesis. Chichester: Wiley, 2001.

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F, Liebman Joel, and Greenberg Arthur, eds. Biophysical aspects. Deerfield Beach, Fla: VCH, 1987.

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Wackym, Phillip A. Molecular temporal bone pathology, parts III and IV. Philadelphia, PA: Lippincott-Raven, 1998.

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Keith, Lierre. The vegetarian myth: Food, justice and sustainability. Crescent City, Ca: Flashpoint Press, 2009.

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Noda, Masaki. Cellular and Molecular Biology of Bone. Elsevier Science & Technology Books, 2014.

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Capitoli di libri sul tema "Bones – Molecular aspects"

Bab, Itai A., and Jona J. Sela. "Cellular and Molecular Aspects of Bone Repair." In Principles of Bone Regeneration, 11–41. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-2059-0_2.

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Hendry, Robin Findlay. "Mechanisms in Chemistry." In History, Philosophy and Theory of the Life Sciences, 139–60. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-46917-6_7.

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AbstractMechanisms are the how of chemical reactions. Substances are individuated by their structures at the molecular scale, so a chemical reaction is just the transformation of reagent structures into product structures. Explaining a chemical reaction must therefore involve different hypotheses about how this might happen: proposing, investigating and sometimes eliminating different possible pathways from reagents to products. One distinctive aspect of mechanisms in chemistry is that they are broken down into a few basic kinds of step involving the breaking and making of bonds between atoms. This is necessary for chemical kinetics, the study of how fast reactions happen, and what affects it. It draws on G.N. Lewis’ identification of the chemical bond as involving shared electrons, which from the 1920s achieved the commensuration of chemistry and physics. The breaking or making of a bond just is the transfer of electrons, so a chemical bond on one side of an equation might be balanced on the other side by the appearance of a corresponding quantity of excess charge. A bond is understood to have been exchanged for a pair of electrons. Since reaction mechanisms rely on identities, doesn’t the establishment of a reaction mechanism explain away the chemical phenomena, showing that they are no more than the movement of charges and masses? In one sense yes: these mechanisms seem to involve a conserved-quantity conception of causation. But in another sense no: the ‘lower-level’ entities can do what they do only when embedded in higher-level organisation or structure. There need be no threat of reduction.

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Okuyama, Tadashi, and Howard Maskill. "Conformation and Strain in Molecules." In Organic Chemistry. Oxford University Press, 2013. http://dx.doi.org/10.1093/hesc/9780199693276.003.0004.

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This chapter explores how internal rotations about single bonds cause some molecules to be flexible rather than to have single fixed shapes. It recalls that four single bonds radiate in tetrahedral directions from a saturated (sp3-hybridized) carbon atom, which leads to organic molecules having three-dimensional structures. The chapter then argues that molecules are not rigid because molecular vibrations cause bond lengths and bond angles to be oscillating constantly about their average values. The chapter then shifts to examine what causes strain in a molecule, and how molecular strain affects the three-dimensional shape of a molecule. It employs several methods to represent the three-dimensional structures of organic molecules in two dimensions, which help us to generate mental images of three-dimensional shapes of organic molecules, and hence better understand stereochemical aspects of organic chemistry. The chapter concludes by discussing conformations of alkanes and cycloalkanes, as well as cis-trans Isomerism in cycloalkanes.

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Tirode, Franck, and Thomas G. P. Grünewald. "Molecular aspects of Ewing's sarcomas." In Bone Cancer, 617–30. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-12-821666-8.00022-0.

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"Cellular and Molecular Aspects." In Stem Cells and Bone Tissue, 123. CRC Press, 2013. http://dx.doi.org/10.1201/b14590-9.

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Mithal, Ambrish. "Skeletal Fluorosis: Molecular Aspects." In Molecular and Cellular Biology of Bone, 797–808. Elsevier, 1998. http://dx.doi.org/10.1016/s1569-2590(08)60152-4.

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Okuyama, Tadashi, and Howard Maskill. "Organic Reactions and the Concept of Mechanism." In Organic Chemistry. Oxford University Press, 2013. http://dx.doi.org/10.1093/hesc/9780199693276.003.0007.

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This chapter shows how the reorganization of chemical bonds as an organic molecule reacts can be related to transformations of the molecular orbitals involved. Chemical transformations involve the redistribution of valence electrons of the reactant molecules. The chapter looks at how this happens, arguing that this is a major aspect of what is called the reaction mechanism. The chapter also illustrates how the redistribution of valence electrons associated with a chemical transformation can be represented by curly arrows. It argues that the reorganization of bonds associated with an organic chemical reaction is not instantaneous. The chapter then describes the reaction profile which includes a representation of the rate of the reaction (the Gibbs energy of activation) and the feasibility of the reaction (the Gibbs energy of reaction). It concludes by investigating organic reaction mechanisms and the reversibility of reactions and equilibrium.

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Bader, Richard F. W. "Atoms In Chemistry." In Atoms in Molecules, 1–12. Oxford University PressOxford, 1990. http://dx.doi.org/10.1093/oso/9780198551683.003.0001.

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Abstract Chemistry is the study of the properties of substances and their transformations. Since substances are identified and distinguished one from another by the elements they contain and since the properties of each element are determined by the atoms unique to that element, chemistry is the study of matter at the atomic level. The realization of this fact by Dalton in 1807 marked the birth of chemistry as a branch of science. Dalton’s atomic hypothesis accounted for the existence of the observed relative combining weights of the elements and predicted a new relationship among them, the law of multiple proportions. Dalton did not simply resurrect the Greek idea of atoms; he postulated that atoms retained their identity even when in chemical combination with other atoms—that atoms exist in molecules. As a result of the work of van’t Hoff and Le Bel in 1874 the geometrical aspect of molecular structure was incorporated into the hypothesis by postulating the existence of preferred geometrical arrangements of bonds terminating at a single atom. Before the close of his century, there had evolved from Dalton’s atomic hypothesis the concept of molecular structure—that a molecule is a collection of atoms linked by a network of bonds, the bonds imparting the structure.

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Mirza, Nasir Saeed, and Munir Pirmohamed. "Molecular medicine and genetics." In Medicine for MRCP, 37–56. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198779506.003.0002.

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This chapter outlines the basic science and theory of molecular medicine and genetics required for MRCP Part 1, before addressing the clinical aspects of molecular medicine and genetics for MRCP Part 2. To ensure effective revision, material is presented in short sections with bullet lists, tables, and boxes to highlight key facts.

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Dewey, T. Gregory. "Fractal Aspects of Protein Structure." In Fractals In Molecular Biophysics, 30–58. Oxford University PressNew York, NY, 1998. http://dx.doi.org/10.1093/oso/9780195084474.003.0002.

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Abstract Proteins are individually sculpted molecules the three-dimensional structure of which is dictated by their amino acid sequence. They are heteropolymers with a variable composition of 20 different amino acids. The amino acid sequence is referred to as the primary structure. For most proteins, the information contained in the primary structure is sufficient to dictate the three-dimensional folding of the protein. The peptide linkages that join the amino acid residues are planar and have two characteristic dihedral angles associated with them. These bond rotations are referred to as the and ‘I’ angles. For steric reasons, the bond angles of proteins fall in localized regions of space. These regions can be used to classify the secondary structural units. Commonly discussed secondary structural units are the alpha helix, beta sheet, beta tum, and random coil. The specification of the folded configuration of the chain is called the tertiary structure. The varied composition and nature of amino acid side-groups result in a range of possible interactions within the polymer. Because of the compact structure of most proteins, amino acid residues that are at distant points in the sequence can be in close proximity in the folded state. These distant residues can be linked by disulfide bridges, salt bridges (electrostatic), or hydrogen bonds. These long-range interactions help dictate the final three-dimensional structure of the molecule.

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Atti di convegni sul tema "Bones – Molecular aspects"

Tarasenko, Oleh. "FEATURES OF BONE REMODELING MECHANISMS: CELLULAR AND MOLECULAR ASPECTS." In EDUCATION AND SCIENCE OF TODAY: INTERSECTORAL ISSUES AND DEVELOPMENT OF SCIENCES, chair Viacheslav Zaborovskyi, Ihor Horishnyi, and Bohdan Zarytov. European Scientific Platform, 2021. http://dx.doi.org/10.36074/logos-29.10.2021.v2.24.

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Asadi, Ehsan, Ali Karimzade, and Mehrdad Farid. "Investigation of the Fundamental Frequency of Double Walled Carbon Nanotubes Using Molecular Mechanics Approach by an Averaging Van Der Waals Forces Modeling." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62962.

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Carbon nanotubes have received a lot of attention since their introduction in 1991 because of novel properties that show substantial promises for use in many applications. Their usage depends on the strength of our knowledge of their properties. In this work, molecular mechanics approach is used to study the mechanical properties of multi-wall carbon nanotubes. In particular this paper investigates fundamental frequency of double walled carbon nanotubes. Carbon nanotubes are big and long molecules that can be regarded as mechanical structures. In modeling of multi-walled carbon nanotubes, two

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Ungur, Petru, Elisabeta Patcas, Petru A. Pop, Silviu Corbu, and Florin M. Marcu. "Theoretical and Practical Aspects About Bio-Lubrication of Synovial Joints by Radioactive Molecular Treatment." In ASME 2008 9th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2008. http://dx.doi.org/10.1115/esda2008-59160.

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The paper has presented the result of tests and researches realized at our university and Oncology Clinical Hospital from Oradea, Radiotherapy Section, about improving of biolubrication between cartilages in relative moving of synovial joints with osteoarthritis, having slow evolution under non-conventional treatment of irradiation with gamma ray. By radioactive molecular treatment of synovial joints with gamma ray, type hinge of knee and spheres of disorder hip (gon-arthrosis and cox-arthrosis), changed molecular structures of porous cartilages and of synovial fluid in contact. All these due

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Silva, Tarcisio Rubens da, Marina Monteiro Navarro, Mylena Mendes Hóstio, and Catherine Sonaly Ferreira Martins. "Case report - Ataxia-telangiectasia: innate error of immunity and neurological aspects." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.233.

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Introduction: Among more than 350 immunological deficiencies, 25% have neurological manifestations. Thus, Ataxia-telangiectasia stands out, being considered a combined immunodeficiency. In childhood, cerebellar motor findings and recurrent sinopulmonary infections, signaling early cerebellar degeneration and deficit in the combined immune response. It has an autosomal recessive inheritance pattern. Case report: She describes herself as a female patient, 9 years old, daughter of consanguineous parents and born in Sousa, Paraíba. In the child’s neuropsychomotor development, she sat down at 5 mon

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van de Ven, T. G. M. "Physiocochemical and Hydrodynamic Aspects of Fines and Fillers Retention." In Fundamentals of Papermaking, edited by C. F. Baker and V. Punton. Fundamental Research Committee (FRC), Manchester, 1989. http://dx.doi.org/10.15376/frc.1989.1.471.

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From the results of model studies on well-characterized systems, valuable conclusions can be drawn regarding several phenomena occurring in papermaking suspensions relevant to fines and fillers retention. We have shown that long range hydrodynamic interactions are operating between small particles (such as fillers) and spheroids (such as fibers) subjected to simple shear, preventing small particles from approaching large ones to within distances where colloidal forces become important. We can expect similar effects in papermaking suspensions, resulting in very low efficiencies for the depositi

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Hirn, U., and R. Schennach. "Fiber-Fiber Bond Formation and Failure: Mechanisms and Analytical Techniques." In Advances in Pulp and Paper Research, Oxford 2017, edited by W. Batchelor and D. Söderberg. Fundamental Research Committee (FRC), Manchester, 2017. http://dx.doi.org/10.15376/frc.2017.2.839.

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In this paper we give a literature overview on three different aspects of pulp fiber-fiber bonding. First we are reviewing how the adhesion between the pulp fibers is created by the capillary pressure during drying of a sheet. Second we are discussing the individual mechanisms relevant for fiber-fiber bonding. They can be grouped in three different groups: (a) The area in molecular contact, which also includes interdiffusion; (b) the intermolecular bonding mechanisms hydrogen bonding, Van der Waals forces and Coulomb interaction; (c) the mechanical bonding mechanisms which are capillary bridge

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Gurskaya, N. A., and K. V. Kobets. "THE RELATIONSHIP OF POLYMORPHIC VARIANTS OF ESTROGEN RECEPTOR GENES WITH THE DEVELOPMENT OF OSTEOPOROSIS IN THE BELARUSIAN POPULATION." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute, 2021. http://dx.doi.org/10.46646/sakh-2021-1-245-248.

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A violation of the hormonal balance is considered one of the factors affecting the development of osteoporosis (OP). The study of the molecular and genetic aspects of this fact will allow us to select a more effective course of OP therapy in the future. Sex hormones, as activators of the expression of a number of genes that regulate bone metabolism, act indirectly through specific receptors. We considered polymorphic variants of the estrogen receptor genes ESR1 and ESR2, encoding the a and в subunits of the estrogen receptor, respectively. Among the studied polymorphic variants of ESR1 (rs9340

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Du, Wenjie, Shuai Zhang, Di Wu, Jun Xia, Ziyuan Zhao, Junfeng Fang, and Yang Wang. "MMGNN: A Molecular Merged Graph Neural Network for Explainable Solvation Free Energy Prediction." In Thirty-Third International Joint Conference on Artificial Intelligence {IJCAI-24}. California: International Joint Conferences on Artificial Intelligence Organization, 2024. http://dx.doi.org/10.24963/ijcai.2024/642.

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In this paper, we address the challenge of accurately modeling and predicting Gibbs free energy in solute-solvent interactions, a pivotal yet complex aspect in the field of chemical modeling. Traditional approaches, primarily relying on deep learning models, face limitations in capturing the intricate dynamics of these interactions. To overcome these constraints, we introduce a novel framework, molecular modeling graph neural network (MMGNN), which more closely mirrors real-world chemical processes.Specifically, MMGNN explicitly models atomic interactions such as hydrogen bonds by initially fo

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Milovanović, Milan R., Jelena M. Živković, Ivana M. Stanković, Dragan B. Ninković, and Snežana D. Zarić. "Repulsive water-water contacts from Cambridge Structural Database." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.637m.

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Water is one of the most important molecules on the Earth. Since water plays a crucial role in many life processes, it is of great importance to understand every aspect of its behavior and interactions with itself and its surroundings. It is known that water molecules can interact via classical hydrogen bonds and antiparallel interactions, with interaction energies of – 5.02 kcal/mol and -4.22 kcal/mol, respectively. Besides these attractive interactions, repulsive interactions were also noticed. In this work, we analyzed repulsive water-water contacts from the Cambridge Structural Database. A

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Ouzounian, Miray, and Travis Shihao Hu. "Nano-Scale Wettability of Free-Standing Capped Carbon Nanotube Arrays." In ASME 2020 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/imece2020-23695.

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Abstract Countless organisms in nature have adapted high-aspect-ratio micro-/nano-fibrillar arrays on their functional surfaces for achieving special and often optimized functionalities using earthly abundant materials. At the core of nanoscience and nanotechnology, rationally mimicking nature offers a promising route to create multifunctional superstructures that capture organisms and biological materials’ intriguing responsive and self-adjusting properties. Prior work has demonstrated that hierarchical vertically aligned multi-walled carbon nanotube (VA-MCNT) arrays can achieve ten folds of

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