Zaloguj się

Gotowe bibliografie tematyczne / Β-amyloid structures / Rozprawy doktorskie

Kliknij ten link, aby zobaczyć inne rodzaje publikacji na ten temat: Β-amyloid structures.

Rozprawy doktorskie na temat „Β-amyloid structures”

Autor: Grafiati

Data publikacji: 23 listopada 2024

Data aktualizacji: 31 lipca 2025

Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych

Wybierz rodzaj źródła:

Sprawdź 25 najlepszych rozpraw doktorskich naukowych na temat „Β-amyloid structures”.

Przycisk „Dodaj do bibliografii” jest dostępny obok każdej pracy w bibliografii. Użyj go – a my automatycznie utworzymy odniesienie bibliograficzne do wybranej pracy w stylu cytowania, którego potrzebujesz: APA, MLA, Harvard, Chicago, Vancouver itp.

Możesz również pobrać pełny tekst publikacji naukowej w formacie „.pdf” i przeczytać adnotację do pracy online, jeśli odpowiednie parametry są dostępne w metadanych.

Przeglądaj rozprawy doktorskie z różnych dziedzin i twórz odpowiednie bibliografie.

1

Newby, Francisco Nicolas. "Structural studies of the Alzheimer's amyloid β peptide". Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607712.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

2

Siegemund, Thomas. "Structure and properties of drug-loaded polymeric nanoparticles targeting β-amyloid". Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-70212.

Pełny tekst źródła

Streszczenie:

Polymere Nanopartikel sind ein vielversprechender Ansatz für die Diagnose und Therapie von Krankheiten. Sie ermöglichen den Einsatz von schwerlöslichen oder instabilen Wirkstoffen. Ein weiterer Vorteil ist die Möglichkeit das Targetings, durch gezielte Modifikationen des Nanopartikels wird der Wirkstoff zum Zielort transportiert und kann dort in der gewünschten Form freigesetzt werden; dadurch könnten bei erhöhter Wirksamkeit die Nebenwirkungen von Medikamenten reduziert werden. Ziel dieser Arbeit war die Untersuchung von physikalischen und biochemischen Eigenschaften von Nanopartikeln besteh

Style APA, Harvard, Vancouver, ISO itp.

3

Daou, Dania. "Intégration de moteurs moléculaires photoactivables dans des gels supramoléculaires." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAF021.

Pełny tekst źródła

Streszczenie:

Cette thèse a exploré l'intégration de moteurs moléculaires synthétiques photoactivables dans des réseaux de gels supramoléculaires. L'objectif principal était d'obtenir un mouvement macroscopique réversible en exploitant à la fois la rotation unidirectionnelle des moteurs moléculaires et la nature réversible des interactions supramoléculaires. Des moteurs moléculaires hautement fonctionnalisés ont été synthétisés et intégrés comme unités de réticulation dans des réseaux de gel supramoléculaire de peptides de diphénylalanine et de poly(γ-benzyl-L-glutamate) et d'oligonucléotides d'ADN. L'activ

Style APA, Harvard, Vancouver, ISO itp.

4

Zhu, Maximillian. "Computational studies of the Alzheimer's amyloid-β peptide : from structural ensembles to therapeutic leads". Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608056.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

5

Cozma, Claudia [Verfasser]. "Determination of Primary Structure and Affinity Characterization of Naturally Occurring β-Amyloid Autoantibodies / Claudia Cozma". Konstanz : Bibliothek der Universität Konstanz, 2014. http://d-nb.info/1079910271/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

6

Wißbrock, Amelie [Verfasser]. "Transient Heme-Protein Interactions: Structural and Functional Studies on Interleukin-36α and Amyloid-β / Amelie Wißbrock". Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1224270444/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

7

Paraschiv, Gabriela Ioana [Verfasser]. "Structural identification and quantification of β-amyloid polypeptide-ligand interactions using affinity-mass spectrometric methods / Gabriela Ioana Paraschiv". Konstanz : Bibliothek der Universität Konstanz, 2012. http://d-nb.info/1025637240/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

8

Cerda, Muñoz Fabian Esteban [Verfasser], Wolfgang [Akademischer Betreuer] Baumeister, Bernd [Gutachter] Reif та Wolfgang [Gutachter] Baumeister. "Structural study of the Amyloid β cytotoxicity / Fabian Esteban Cerda Muñoz ; Gutachter: Bernd Reif, Wolfgang Baumeister ; Betreuer: Wolfgang Baumeister". München : Universitätsbibliothek der TU München, 2021. http://d-nb.info/1230552790/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

9

Dammers, Christina [Verfasser], Dieter [Gutachter] Willbold та Henrike [Gutachter] Heise. "Structural analysis and aggregation of Alzheimer’s disease related pyroglutamate-modified amyloid-β / Christina Dammers ; Gutachter: Dieter Willbold, Henrike Heise". Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2017. http://d-nb.info/1132771757/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

10

Dammers, Christina Verfasser], Dieter [Gutachter] [Willbold та Henrike [Gutachter] Heise. "Structural analysis and aggregation of Alzheimer’s disease related pyroglutamate-modified amyloid-β / Christina Dammers ; Gutachter: Dieter Willbold, Henrike Heise". Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2017. http://d-nb.info/1132771757/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

11

RIZZA, FABIO. "Structural modelling of biological macromolecules: the cases of neurofibromin, bifurcating Electron Transferring Flavoprotein and Amyloid-β (1-16) peptide". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/310480.

Pełny tekst źródła

Streszczenie:

In questa tesi sono stati affrontati tre progetti indipendenti, accomunati dall’uso della modellistica molecolare e in particolare della dinamica molecolare. Nel primo progetto è stato studiato il dominio Sec14-PH della neurofibromina (NF1). I domini sec14 sono stati scoperti in numerose proteine dai procarioti all’uomo come scambiatori di lipidi tra membrane, per mezzo di una tasca la cui apertura è legata al movimento di una specifica alpha-elica (elica lid). La struttura cristallina del dominio Sec14 di NF1 (sia del wild type sia di mutanti associati all’insorgenza della patologia neurofib

Style APA, Harvard, Vancouver, ISO itp.

12

Mohammadi, Azadeh. "Apolipoprotein E isoform specific differences on their tertiary structure and on their interaction with amyloid-β peptide: Structural and dynamics studies by cross-linking mass spectrometry and in silico modeling". Doctoral thesis, Universite Libre de Bruxelles, 2017. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/257269.

Pełny tekst źródła

Streszczenie:

La maladie d’Alzheimer (MA) est un désordre neuro-dégénératif chronique fatal et la forme la plus répandue des démences chez l’adulte qui touchent plus de 28 millions de personnes dans le monde. En absence de traitement pour les démences neurodégénérative dont la maladie d’Alzheimer, le coût de celles-ci est estimé à 1 trillion d’USD en 2018 ce qui représente des enjeux économiques et sociétaux majeurs au niveau national et mondial. La MA est une forme d’amylose qui est caractérisée par l’agrégation du peptide amyloïde beta (Aβ) dans le cerveau des patients. Le facteur de risque génétique prin

Style APA, Harvard, Vancouver, ISO itp.

13

Siegemund, Thomas [Verfasser], Josef [Akademischer Betreuer] Käs, Josef [Gutachter] Käs, Wolfgang [Akademischer Betreuer] Härtig, Herbert [Akademischer Betreuer] Schmiedel та Mathias [Gutachter] Winterhalter. "Structure and properties of drug-loaded polymeric nanoparticles targeting β-amyloid / Thomas Siegemund ; Gutachter: Josef Käs, Mathias Winterhalter ; Josef Käs, Wolfgang Härtig, Herbert Schmiedel". Leipzig : Universitätsbibliothek Leipzig, 2011. http://d-nb.info/1237894417/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

14

Diez, Lisa [Verfasser]. "Structure-based discovery of small molecule inhibitors of seeding activity in Alzheimer's disease biosamples using a fluorescence polarization-based amyloid-β aggregation assay / Lisa Diez". Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1196802955/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

15

Palmblad, Magnus. "Identification and Characterization of Peptides and Proteins using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry." Doctoral thesis, Uppsala universitet, Institutionen för materialvetenskap, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1999.

Pełny tekst źródła

Streszczenie:

Mass spectrometry has in recent years been established as the standard method for protein identification and characterization in proteomics with excellent intrinsic sensitivity and specificity. Fourier transform ion cyclotron resonance is the mass spectrometric technique that provides the highest resolving power and mass accuracy, increasing the amount of information that can be obtained from complex samples. This thesis concerns how useful information on proteins of interest can be extracted from mass spectrometric data on different levels of protein structure and how to obtain this data expe

Style APA, Harvard, Vancouver, ISO itp.

16

Siegemund, Thomas. "Structure and properties of drug-loaded polymeric nanoparticles targeting β-amyloid". Doctoral thesis, 2010. https://ul.qucosa.de/id/qucosa%3A11216.

Pełny tekst źródła

Streszczenie:

Polymere Nanopartikel sind ein vielversprechender Ansatz für die Diagnose und Therapie von Krankheiten. Sie ermöglichen den Einsatz von schwerlöslichen oder instabilen Wirkstoffen. Ein weiterer Vorteil ist die Möglichkeit das Targetings, durch gezielte Modifikationen des Nanopartikels wird der Wirkstoff zum Zielort transportiert und kann dort in der gewünschten Form freigesetzt werden; dadurch könnten bei erhöhter Wirksamkeit die Nebenwirkungen von Medikamenten reduziert werden. Ziel dieser Arbeit war die Untersuchung von physikalischen und biochemischen Eigenschaften von Nanopartikeln besteh

Style APA, Harvard, Vancouver, ISO itp.

17

Chang, Yu-Ning, та 張右檸. "Structural characterization of Iowa-type β-amyloid peptide in LMPG micelles". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/40465982589620525630.

Pełny tekst źródła

Streszczenie:

碩士<br>國立陽明大學<br>生化暨分子生物研究所<br>104<br>Alzheimer’s disease (AD) is the most common cause of dementia in elderly people. It is a chronic neurodegenerative disease. Currently, the hypothesis for the pathogenic mechanism of AD is amyloid cascade hypothesis. It states that the aggregation of β-amyloid (Aβ) is the primary cause of AD. Aβ contains 39-42 residues amino acid. It was a proteolytic product derived fromβ-amyloid precursor protein (βAPP). The aggregation process of Aβ involves conformational changes and self-assembly, indicating that the structural property plays an important role in Aβ agg

Style APA, Harvard, Vancouver, ISO itp.

18

Ssu-HanWu та 吳思翰. "Structure-neurotoxicity relationship of soluble amyloid-β globulomer using molecular dynamics simulations". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/21293149558259265894.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

19

Chang, Han-Chen, та 張翰珍. "Expression and purification 13C- and 15N-labeled β-amyloid peptide and β-amyloid precursor protein 672-731(APP 672-731) for NMR structural analysis and study". Thesis, 2006. http://ndltd.ncl.edu.tw/handle/24635368587136075858.

Pełny tekst źródła

Streszczenie:

碩士<br>國立中正大學<br>分子生物研究所<br>94<br>Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the progressive deposition of the aggregated amyloid β-peptide (Aβ) on the cell surfaces and in the walls of cerebral blood vessels. Aβ is a 39-43 amino acid polypeptide derived from proteolytic cleavages of the β-amyloid precursor protein (APP) by β- and γ-secretase. There are three groups of mutation sites in APP found in AD patients. These mutation sites locate near the ?, β- and γ-secretase cutting sites. It is believed that mutations near the β- and γ-secretase cutting sites induce a

Style APA, Harvard, Vancouver, ISO itp.

20

Huang, Wei, та 黃瑋. "Study of the structure and aggregative behavior of Dutch-type β-amyloid in LMPG micelles". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/3ebh4f.

Pełny tekst źródła

Streszczenie:

碩士<br>國立陽明大學<br>生命科學系暨基因體科學研究所<br>104<br>Alzheimer's disease (AD) a chronic neurodegenerative disease. It is the main cause of dementia in the elderly people. β-amyloid peptide (Aβ) is the main component of neuritic plaques which are a pathological hallmark of AD. β-amyloid peptide (Aβ) contains 39~42 amino acid residues. It was a proteolytic product derived from β-amyloid precursor protein (βAPP). Currently, the leading theory for explaining the etiology and pathogenesis of AD is the “Amyloid cascade hypothesis” which stated that Aβ aggregation resulted in brain cell death and dementia. Studi

Style APA, Harvard, Vancouver, ISO itp.

21

Mendoza, Vanessa Leah C. "Structural characterization of the pre-amyloid oligomers of β-2-microglobulin using covalent labeling and mass spectrometry". 2010. https://scholarworks.umass.edu/dissertations/AAI3427594.

Pełny tekst źródła

Streszczenie:

The initial steps involved in the assembly of normally soluble proteins into amyloid fibrils remain unclear, yet over 20 human diseases are associated with proteins that aggregate in this manner. Protein surface modification is a potential means of mapping the interaction sites in early oligomers that precede amyloid formation. This dissertation focuses on the use of covalent labeling combined with mass spectrometry to elucidate the structural features of Cu(II)-induced β-2-microglobulin (β2m) amyloid formation. An improved covalent modification and MS-based approach for protein surface mappin

Style APA, Harvard, Vancouver, ISO itp.

22

Mendoza, Vanessa Leah Castillo. "Structural Characterization of the Pre-Amyloid Oligomers of β-2-Microglobulin Using Covalent Labeling and Mass Spectrometry". 2010. https://scholarworks.umass.edu/open_access_dissertations/293.

Pełny tekst źródła

Streszczenie:

The initial steps involved in the assembly of normally soluble proteins into amyloid fibrils remain unclear, yet over 20 human diseases are associated with proteins that aggregate in this manner. Protein surface modification is a potential means of mapping the interaction sites in early oligomers that precede amyloid formation. This dissertation focuses on the use of covalent labeling combined with mass spectrometry to elucidate the structural features of Cu(II)-induced β-2-microglobulin (β2m) amyloid formation. An improved covalent modification and MS-based approach for protein surface mappin

Style APA, Harvard, Vancouver, ISO itp.

23

Wang, Hsiang-Ling, та 王翔翎. "A theoretical study on the structure of copper-binding peptides :Implications in the aggregation of β-amyloid (Aβ) peptide". Thesis, 2008. http://ndltd.ncl.edu.tw/handle/73544984220527092657.

Pełny tekst źródła

Streszczenie:

碩士<br>國立中興大學<br>化學系所<br>96<br>Amyloid-β peptide (Aβ) is the principal constituent of plaques and fibrils associated with Alzheimer’s disease (AD) and is thought to be responsible for the neurotoxicity associated with the disease. Copper binding to Aβ has been hypothesized to play an important role in the neruotoxicity of Aβ. However, many properties of copper binding to Aβ have not been elucidated clearly, and the location of copper binding sites on Aβ is also in controversy. In this work, several possible models containing copper(II) coordinating with His residues of Aβ related to fibril form

Style APA, Harvard, Vancouver, ISO itp.

24

Chang, Liang-Kai, та 張量凱. "Molecular Dynamics Simulations to Investigate the Structural Stability and Aggregation Behavior of the GGVVIA and MVGGVV Oligomers Derived from Amyloid β Peptide". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/pd56ur.

Pełny tekst źródła

Streszczenie:

碩士<br>國立臺北科技大學<br>生物科技研究所<br>97<br>Several neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, are associated with amyloid fibrils formed by different polypeptides. Recently, the atomic structure of the amyloid-forming peptides GGVVIA and MVGGVV from the C-terminal hydrophobic segment of amyloid-β (Aβ) peptide has been determined and revealed a dry, tightly self-complementing structure between two β-sheets, termed as “steric zipper”. In this study, several all-atom molecular dynamics simulations with explicit water were conducted to investigate the structur

Style APA, Harvard, Vancouver, ISO itp.

25

Guerreiro, Marta Lúcia Amaro. "Structural characterization and comparative analysis of human and piscine cartilage acidic protein (CRTAC1/CRTAC2)." Master's thesis, 2014. http://hdl.handle.net/10400.1/8345.

Pełny tekst źródła

Streszczenie:

Dissertação de mestrado, Biotecnologia, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2014<br>CRTAC (Cartilage Acidic Protein) firstly identified as a chondrocyte marker in humans and implicated in a number of diseases. This ancient protein is present from prokaryotes to vertebrates and the teleost are the only group that contain duplicates (CRTAC1/CRTAC2). The structure of CRTACs is poorly characterized and was the starting point of the present study. To establish the molecular and structural characterization of CRTAC, three recombinant proteins [human (h) CRTAC1 and sea

Style APA, Harvard, Vancouver, ISO itp.

Oferujemy zniżki na wszystkie plany premium dla autorów, których prace zostały uwzględnione w tematycznych zestawieniach literatury. Skontaktuj się z nami, aby uzyskać unikalny kod promocyjny!