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Artykuły w czasopismach na temat "616.079 202 8557"

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Özdemir Işik, Ö., S. Şan, A. Yazici, and A. Cefle. "AB0356 VENOUS INVOLVEMENT IN BEHÇET’S DISEASE." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1202.1–1203. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1144.

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Background:Behçet’s disease (BD) is a vasculitic multisystem inflammatory disorder. It may also involve the skin, mucosa, eyes, blood vessels, joints, gastrointestinal system, and central nervous system.Objectives:In this study, we aimed to present venous involvement data in patients followed up with a diagnosis of BD.Methods:The clinical, demographic, laboratory and medication data of 394 patients who were followed up with a diagnosis of BD in our rheumatology outpatient clinic between 2000 and 2020 were retrospectively evaluated.Results:Venous involvement was detected in 17.6% (n:76) patient
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Monosi, B., I. Cristiano, E. Capparelli, et al. "POS0872 CHARACTERIZATION AND RISK FACTORS FOR LUNG INVOLVEMENT IN PSORIATIC ARTHRITIS: DATA FROM A SINGLE RHEUMATOLOGIC CENTRE." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 742.1–742. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3339.

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BackgroundPsoriatic arthritis (PsA) is a chronic inflammatory systemic disease associated with several comorbidities. Few data are available concerning the association between psoriasis (PsO) and lung disease (LD), such as chronic obstructive pulmonary disease (COPD)[1]and interstitial lung disease (ILD)[2]. This association has also been hypothesized in PsA. Therefore, evaluating distinct lung manifestations in PsA could be an important driver to improve patients’ management.ObjectivesTo assess the prevalence and clinical features of PsA, to examine the co-occurrence of different LDs patterns
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Scotté, Florian, Kamel Laribi, Christian Gisselbrecht, et al. "Treatment of Chemotherapy-Induced Anemia Using Epoetin Alfa Biosimilar for Patients with Lymphoma and Myeloma: The Synergy Study." Blood 126, no. 23 (2015): 952. http://dx.doi.org/10.1182/blood.v126.23.952.952.

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Background Recommendations on erythropoiesis-stimulating agents for the management of chemotherapy-induced anemia (CIA) are well established (Schrijvers D et al. Ann Oncol 2010;21[suppl 5]:v244-7). Iron supplementation can further improve treatment response of CIA, particularly in the case of iron deficiency (Pedrazzoli P et al. J Clin Oncol 2008;26:1619-25; Auerbach M et al. J Clin Oncol 2004;22:1301-7), but is under-used. Objective To evaluate the effect of epoetin alfa biosimilar, with or without iron, on CIA in current oncology and hematology practice. Methods SYNERGY was an observational,
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Gogate, Anagha, Amanda Crosbie, Trong Kim Le, Ying Zhang, Rolee Das, and Catherine Davis. "Abstract P3-12-15: Clinical characteristics, treatment patterns, and survival outcomes in women with early triple-negative (TN) or hormone receptor-positive/human epidermal growth factor receptor-2 negative (HR+/HER2−) breast cancer (BC) in the real-world (RW) setting." Cancer Research 82, no. 4_Supplement (2022): P3–12–15—P3–12–15. http://dx.doi.org/10.1158/1538-7445.sabcs21-p3-12-15.

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Abstract Background: BC remains the most commonly diagnosed cancer for women. TNBC is an aggressive form with a poorer prognosis compared with other subtypes. Neoadjuvant therapy (NAT) is the standard-of-care approach to shrink tumors in the breast and axilla and to improve patient outcomes. Few RW studies exist of US patients with early BC (eBC); this study aimed to describe clinical parameters by receipt of systemic therapy and to assess overall survival (OS) and progression-free survival (PFS) after NAT and adjuvant therapy (AT) in women with early HR+/HER2− or TNBC using RW evidence in the
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Fenske, Timothy S., Xin Victoria Wang, Brian G. Till, et al. "Lack of Benefit of Autologous Hematopoietic Cell Transplantation (auto-HCT) in Mantle Cell Lymphoma (MCL) Patients (pts) in First Complete Remission (CR) with Undetectable Minimal Residual Disease (uMRD): Initial Report from the ECOG-ACRIN EA4151 Phase 3 Randomized Trial." Blood 144, Supplement 2 (2024): LBA—6—LBA—6. https://doi.org/10.1182/blood-2024-212973.

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Abstract Background: MCL is a B-cell non-Hodgkin lymphoma for which auto-HCT is often employed in first CR, based on non-randomized phase 2 trials, and a randomized trial (Dreyling et al, Blood 2005) conducted before the advent of more effective induction and maintenance regimens. The TRIANGLE trial (Dreyling et al, Lancet 2024) suggested that auto-HCT may not add benefit to more effective induction and maintenance regimens containing high-dose cytarabine, rituximab and BTK inhibitors. E4151 explored whether auto-HCT benefits pts achieving deep first remission, as measured by a highly sensitiv
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Hosing, Chitra, Zachary Braunstein, Alaa M. Ali, et al. "Romidepsin in Conditioning and Maintenance Mitigates Relapse Risk and Enhances NK-Cell Cytotoxicity in Patients Receiving Allogeneic Stem Cell Transplant for Aggressive T-Cell Malignancies: Results of a Phase I/II Clinical Trial." Blood 138, Supplement 1 (2021): 553. http://dx.doi.org/10.1182/blood-2021-152833.

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Abstract Background: Allo-SCT is the only curative option for patients with high risk and relapsed/refractory T-cell malignancies. Even among allo-SCT recipients, survival is less than 50% and relapse rates are 55-60%. We developed a clinical trial to decrease relapse after allo-SCT for these patients using romidepsin (rom), a histone deacetylase inhibitor approved for the treatment of relapsed T-cell lymphomas. Based on pre-clinical data demonstrating enhanced and synergistic cell killing with the addition of rom to busulfan (Bu) and fludarabine (Flu) in malignant T-cells, we created a novel
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Hardwick, Josephine L., Benjamin J. Ahern, Kylie L. Crawford, et al. "Yearling laryngeal function grades II.2 and below are not associated with reduced performance." Equine Veterinary Journal, January 21, 2025. https://doi.org/10.1111/evj.14452.

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AbstractBackgroundThe relationship between Thoroughbred yearling laryngeal function (YLF) grade and race performance is unclear.ObjectivesTo determine the effect of YLF on future race performance.Study designRetrospective cohort study.MethodsPost‐sale endoscopic recordings were reviewed from Australian yearling sales in 2018–2019. Race performance was evaluated for career and as 2‐, 3‐ and ≥4‐year‐olds. Multivariable generalised linear modelling examined the association between YLF and performance, with risk estimates presented as coefficients (95% CI).ResultsThe YLF in 5175 examinations was g
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Bomans, Leandro, Arianis Tatiana Ramirez, Peter Hillemanns, Murat Gultekin, and Marc Arbyn. "Prediction of Treatment Failure After Excisional Treatment of Cervical Precancer." Obstetrics & Gynecology, July 10, 2025. https://doi.org/10.1097/aog.0000000000005997.

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OBJECTIVE: To evaluate the diagnostic accuracy and clinical utility of posttreatment tests to predict treatment failure after excisional treatment of cervical intraepithelial neoplasia grade 2 or worse (CIN 2+). DATA SOURCES: Electronic databases (EMBASE, PubMed MEDLINE) were searched for studies published from January 1975 to August 2024 assessing the occurrence of treatment failure in women who underwent excisional treatment for histologically confirmed CIN 2+ lesion. METHODS OF STUDY SELECTION: Previously published meta-analyses were extended and updated. A total of 1,802 studies were revie
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Yang, Teng, Jiawei Wang, Jing Huang, Frank J. Kelly, and Guoxing Li. "Long-term Exposure to Multiple Ambient Air Pollutants and Association With Incident Depression and Anxiety." JAMA Psychiatry, February 1, 2023. http://dx.doi.org/10.1001/jamapsychiatry.2022.4812.

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ImportanceAir pollution is increasingly recognized as an important environmental risk factor for mental health. However, epidemiologic evidence on long-term exposure to low levels of air pollutants with incident depression and anxiety is still very limited.ObjectivesTo investigate the association of long-term joint exposure to multiple air pollutants with incident depression and anxiety.Design, Setting, and ParticipantsThis prospective, population-based cohort study used data from the UK Biobank. The participants were recruited between March 13, 2006, and October 1, 2010, and included individu
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Colaneri, M., G. Montrucchio, G. Scaglione, et al. "P01. The IMPACT-VAP study: incidence and mortality of ventilator-associated pneumonia in critically ill patients: results from the PROSAFE project." JAC-Antimicrobial Resistance 7, Supplement_2 (2025). https://doi.org/10.1093/jacamr/dlaf046.001.

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Abstract Background Despite preventive measures, ventilator-associated pneumonia (VAP) persists as the most frequent healthcare-associated infection in intensive care units (ICUs),1 with high incidence and mortality rates.2,3 Here, we wanted to study the incidence of VAP in 192 Italian ICUs in the last decade. Secondly, we wanted to describe the clinical and microbiological characteristics. Finally, we wanted to assess the variables associated with their intra-ICU mortality. Methods In this multicentric observational study, data from 192 Italian ICUs were retrieved from the PROSAFE project, a
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