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Rozprawy doktorskie na temat „Abiotic stress systems biology”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Kleinjan, Hetty. "The influence of bacteria on the adaptation to changing environments in Ectocarpus : a systems biology approach." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS267.

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Ectocarpus dépend de bactéries associées pour croitre en eau douce, ce qui souligne l'importance de l'holobionte lors de stress abiotique. Le but de ma thèse est d'élucider les mécanismes moléculaires qui sous-tendent ce phénomène. Les expériences de co-culture ciblées nécessitent des organismes cultivables. Par conséquent, j'ai caractérisé 388 bactéries associées à Ectocarpus, réparties en 33 genres. Aucune des bactéries cultivées testées n'a eu d'effet bénéfique sur la croissance des algues dans l'eau douce. J'ai continué à travailler avec des holobionts, traités aux antibiotiques doux, qui

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Abwao, Stephen Indieka. "Translational control of abiotic stress responses in Arabidopsis thaliana." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3502/.

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A detailed understanding of the mechanisms by which plants sense and respond to major environmental stress factors will significantly contribute towards the prospects of developing crops capable of yielding well over a wider geographical range, including marginalised lands. One of the important stress response mechanisms in eukaryotes is mediated through phosphorylation of the eIF2α-subunit (serine 51/56) by specific kinases, namely double stranded RNA activated protein kinase (PKR), General Control Non-repressible 2 protein kinase (GCN2), Pancreatic eIF2α kinase (PERK) and Heme-regulated inhi

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Weerathunga, Arachchilage Achira S. "A Novel Transcription Factor in Arabidopsis thaliana Abiotic Stress Response." ScholarWorks@UNO, 2015. http://scholarworks.uno.edu/td/2114.

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Plants respond to environmental stress by altering their gene expression. Under stress conditions some genes are activated and some genes are repressed. Even though a lot of work has been done to understand mechanisms of gene activation under abiotic stress very little information is available on how stress responsive genes are kept repressed under normal growth conditions. Recent work has revealed that plants use transcriptional repression as common mechanism of gene repression. Transcriptional repression is achieved by recruitment co-repressor complexes to the target genes. Recent studies ha

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Guragain, Bhuwan. "Transcriptional co-repressor response of Arabidopsis thaliana to different abiotic stress." ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/td/1738.

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Plants adapt to the complex environmental challenges by regulating their gene expression. Analyses of plant genomes have identified many genes that are either expressed or repressed during environmental stress. However we do not have much information on gene repression. Transcriptional repression in Arabidopsis thaliana is caused by co-repressors that lack the DNA binding domain and are recruited by transcription factors to regulate target gene expression. The Sridhar lab has identified co-repressors SLK1, SLK2, and LUH, which prevent the expression of stress response genes under non-stress co

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Davis, Emily. "Molecular characterization of ALDRXv4, an aldose reductase orthologue isolated from xerophyta viscosa, in response to abiotic stress." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/4254.

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Wu, Qingyu. "Improvement of abiotic stress tolerance and calcium-deficiency disorder resistance of tomato plants." Diss., Kansas State University, 2012. http://hdl.handle.net/2097/14033.

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Doctor of Philosophy<br>Department of Horticulture, Forestry, and Recreation Resources<br>Sunghun Park<br>Plants are continuously exposed to numerous abiotic stresses, which adversely affect plant growth, development, and yield. Plants have developed different signaling pathways to cope with abiotic stresses, and some of the pathways converge to help plants tolerate simultaneous stresses. Here, we report ectopic expression of an Arabidopsis glutaredoxin AtGRXS17 that confers tolerance to multiple abiotic stresses in tomato plants. In yeast assays, AtGRXS17 co-localized with yeast ScGrx3 in the

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John-Bejai, Carus Kristoff Joel. "Wheat floral biology : prospects for improving the efficiency of hybrid seed production and abiotic stress tolerance." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/49925/.

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The modification of floral characteristics will be beneficial in improving the efficiency of hybrid seed production and the breeding of more climate resilient varieties in bread wheat (Triticum aestivum). Methods for phenotyping floral traits were initially tested using small genotype panels under controlled conditions and in field trials. Low-tech phenotyping methods appropriate for use by breeders and researchers were developed and demonstrated to be accurate. A panel of 111 genotypes was subsequently assessed in field trials using these methods. A high level of genotypic variation was obser

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Modi, Sheetal. "Systems biology approaches to mechanisms of bacterial stress adaptation." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12822.

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Thesis (Ph.D.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Bacteria exhibit highly adaptive behaviors in the face of stress, which poses significant challenges for the eradication of infectious disease as well as for the success of biotechnology efforts to harness micr

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Fredén, Linnéa. "The Impact of Abiotic Stress on Alternative Splicing in Lipid Transfer Protein in Marchantia polymorpha." Thesis, Linköpings universitet, Biologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-148738.

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All plants have a protection against the surrounding environment called a cuticle coating. When this cuticle coating is constructed it is believed that the family of protein called lipid transfer proteins (LTPs) is involved. The LTPs are small and cysteine rich. In Marchantia polymorpha the groups of LTPs called LTPd and LTPg can be found. 8 and 4 in each group respectively. In the genes of LTPd there is an intron placed downstream of the start codon. Firstly, a sequence database search was performed and LTPd2 and LTPd3 were chosen for further experiments in this study. Secondly, a control tha

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Maaß, Victoria [Verfasser], Edgar [Gutachter] Peiter, and Yiyong [Gutachter] Zhu. "Establishment of a plant-based system for identifying phytoeffectors and analysis of phytoeffector targets under abiotic stress in Arabidopsis / Victoria Maaß ; Gutachter: Edgar Peiter, Yiyong Zhu." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://d-nb.info/1217251162/34.

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Peters, Shaun W. "XvGoIS, a galactinol synthase is transcriptionally upregulated under water deficit : the role of raffinosaccharides in abiotic stress tolerance in the resurrection plant Xerophyta viscosa (Baker)." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/4318.

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Includes bibliographical references (leaves 84-102).<br>As part of an ongoing project to genetically manipulate maize for increased abiotic stress tolerance, we have isolated and identified a number of genes from the resurrection plant Xerophyta viscosa (Baker) that are differentially expressed during water deficit. A cDNA was isolated from a library constructed from the leaves of water stressed X viscosa plants, which showed high identity to galactinol synthase (GoIS) enzymes from a variety of plant species. GolS is fundamental to the biosynthesis of raffinose family oligosachharides (RFOs),

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Ohneck, Emily Jean. "Interaction of Acinetobacter baumannii with abiotic and biotic environments." Miami University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=miami147937747636766.

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Nordstedt, Nathan P. "Isolation and characterization of novel bacterial strains to alleviate abiotic stress in greenhouse ornamental crops." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1617740819791342.

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Thomas, Elizabeth. "Expression Analysis of Plant Defense Responses during the Establishment of Biotrophy and Role of Abiotic Stress in the Infection of Dyer’s Woad (Isatis tinctoria) by Puccinia thlaspeos." DigitalCommons@USU, 2008. https://digitalcommons.usu.edu/etd/122.

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The kinetics and amplitude of the salicylic acid-responsive pathogenesis-related (PR) genes and the cytochrome P450 gene ItCYP79B2 in the compatible interaction between Puccinia thlaspeos and dyer’s woad (Isatis tinctoria) during the first 72 hours of inoculation were examined. Immediately following penetration of the host by the rust pathogen, there was a modest up-regulation of PR genes but a significant down-regulation of ItCYP79B2 expression. During haustoria formation, a significant pathogen-mediated suppression of PR genes was observed with a corresponding up-regulation of ItCYP79B2. Thi

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Madden, Robert T. "Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality." Scholar Commons, 2019. https://scholarcommons.usf.edu/etd/7853.

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Fresh fruits and vegetables (FFVs) are the most frequently wasted foods because of their perishability and handling requirements. However, there is a lack of information on how much each step of the supply chain impacts FFVs quality, particularly on tomatoes, and what measures need to be taken for an immediate and effective impact on waste reduction. There is also no information on how the supply chain affects the proteome of the tomato and what proteins are differentially regulated by the most impactful steps of the supply chain. The objectives of the work presented on this thesis were to eva

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Ahlsén, Hanna. "The Effects of Abiotic Stress on Alternative Splicing in Non-specific Lipid Transfer Proteins in Marchantia polymorpha." Thesis, Linköpings universitet, Biologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-148937.

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Due to global warming, our planet will experience more extreme weather conditions. Plants can protect themselves against these abiotic stress conditions with their stress response, which includes alternative splicing of certain genes. Alternative splicing is a post-transcriptional process where a single gene gives rise to different mRNAs, which in turn produces different proteins. In plants, this is usually done by intron retention. One type of protein that may be involved in this stress response are the non-specific lipid transfer proteins (LTPs). Indeed, evidence of intron retention has been

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Almazroue, Hanadi Abdulaali. "Identification, Cloning, and Expression of Tobacco Responsive to Dehydration like Protein (RD22), SBIP-355 and Its Role in SABP2 Mediated SA Pathway in Plant Defense." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etd/2456.

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Abscisic acid (ABA) induces RD22, responsive to dehydration stress gene. Salicylic acid (SA) has been the focus of research due to its role against pathogens and abiotic stress. Interaction between ABA and SA signaling pathways is still poorly understood. SA-Binding Protein 2 (SABP2) converts methyl salicylate to SA. An attempt was made to identify proteins that interact with SABP2 using a yeast 2-hybrid screening. Several interactors were identified. One of them, SA-Binding Protein 2 Interacting Protein-355 (SBIP-355), showed high homology to RD22. Bioinformatic approaches showed that SBIP-35

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Kelly, Katrina E. "Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7314.

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Plants inherently produce polyphenols (i.e., antioxidants) as a response to reduce oxidative stress caused by abusive environmental pre- and postharvest conditions. These antioxidants, as well as vitamin C, are present in considerable levels in strawberries; however, excessive oxidative stress brought on by improper postharvest handling conditions can reduce the levels of antioxidants in the fruit and shorten the shelf-life of strawberries. Nevertheless, it may be possible to utilize strawberry’s naturally occurring polyphenols to reduce postharvest stress and extend their shelf life. The poly

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Helman, Tessa J. "The Systems Biology of Chronic Stress in Mice: Integrated Neurobiological, Behavioural and Cardiovascular Outcomes." Thesis, Griffith University, 2022. http://hdl.handle.net/10072/412435.

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The demands of modern life are often challenging and require psychological efforts in order to be effectively met. Conserved through evolution, acute psychological stress (in response to an acute threat) activates physiological systems that are advantageous, exerting appropriately timed responses to promote survival. However, the advantageous outcomes of the acute stress response are reversed under prolonged conditions (chronic stress), detrimentally influencing biological processes and/or behaviours and increasing disease risks. This disease risk is imposed on virtually all organ systems, and

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Shrestha, Barsha. "Identification Of The Transcriptional Co-Repressor Complex And Its Functions In Arabidopsis thaliana." ScholarWorks@UNO, 2014. http://scholarworks.uno.edu/td/1833.

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McDonagh, Andrew N. "Comparative genomics and systems biology of environmental stress responses relevant to fungal virulence." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/11825.

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Serafini, Loredana. "The proteomic response of sea squirts (genus Ciona congeners) to heat stress: Evidence for differential thermal sensitivities." DigitalCommons@CalPoly, 2011. https://digitalcommons.calpoly.edu/theses/443.

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The sea squirts Ciona intestinalis and C. savignyi have disparate distribution patterns, which may result from differences in their thermal tolerance limits. Because C. intestinalis, an almost cosmopolitan species, has a more widespread distribution, it is thought that it is better adapted to endure a wide range of temperatures. In order to compare the heat stress response between these two congeners, we studied global changes in protein expression, using a proteomics approach. To characterize the response to extreme heat stress, animals of both species were exposed to temperatures of 22°C, 25

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Larkindale, Jane. "Cell signalling in response to heat shock in Arabidopsis thaliana." Thesis, University of Oxford, 2001. http://ora.ox.ac.uk/objects/uuid:dc24f743-a69b-4aa9-92a4-fbdcbcff2bef.

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Increases in temperature damage plant cells, and plants react to heat stress by inducing of a number of protective mechanisms. In this study, it has been shown that heat damages cells both directly while the plants are being heated, and indirectly through heat induced oxidative stress during recovery from heating. Different stress response pathways are induced in each case. Evidence implicates salicylic acid, abscisic acid, ACC (a precursor of ethylene), calcium ions and active oxygen species in pathways resulting in thermotolerance (i.e. increased survival at high temperature). Addition of th

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Bishop, Nichole Danielle. "The Effects of Multiple Abiotic Stressors on the Susceptibility of the Seagrass Thalassia Testudinum to Labyrinthula sp., the Causative Agent of Wasting Disease." UNF Digital Commons, 2013. http://digitalcommons.unf.edu/etd/471.

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In the past century, seagrasses have experienced massive die off episodes in what has been collectively referred to as “wasting disease.” Researchers generally agree that wasting disease is caused by a protist of the Labyrinthula genus, and that environmental stressors can make some populations of seagrasses more susceptible to infection. The purpose of this study was to examine the combined effects of elevated salinity, elevated temperature, elevated sulfide and night-time hypoxia on Thalassia testudinum health and its response to Labyrinthula sp. infection under controlled conditions. To tes

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Brock, Kelly Paige. "Protein structure and interaction under environmental stress : from quality control recognition to evolution of collective behavior." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104575.

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Thesis: Ph. D., Massachusetts Institute of Technology, Computational and Systems Biology Program, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>A protein's function in the cell depends on its structure, which in turn depends on the intracellular environment. Stress like heat shock or nutrient starvation can alter intracellular conditions, leading to protein misfolding - i.e. the inability of a protein to reach or maintain its native conformation. Since many proteins interact with each other, protein misfolding and cellular stress response must be exa

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Tuli, Leepika. "Proteome Profiling of Saccharomyces cerevisae stress response to Cumene Hydroperoxide (CHP)." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/28620.

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Oxidative stress, described as the state of disturbed intracellular redox balance, has been associated with several human conditions including ageing, apoptosis, cancer, autoimmune and neuro-degenerative diseases. Stress studies have shown that reactive oxygen species (ROS) and reactive nitrogen species (RNS) along with its intermediates can attack essential cell targets such as: DNA, proteins, lipids and carbohydrates, leaving behind dysfunctional biologic molecules. In effect, a cellâ s primary response is to involve several defense mechanisms that are under a complex and intricate regulato

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El-rami, Fadi. "A Systems Biology Approach For Predicting Essential Genes and Deciphering Their Dynamics Under Stress In Streptococcus sanguinis." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4925.

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Infectious diseases are the top leading cause of death worldwide. Identifying essential genes, genes indispensable for survival, has been proven indispensable in defining new therapeutic targets against pathogens, major elements of the minimal set genome to be harnessed in synthetic biology, and determinants of evolutionary relationships of phylogenetically distant species. Thus, essentiality studies promise valuable revenues that can decipher much of biological complexities. Taking advantage of the available microbial sequences and the essentiality studies conducted in various microbial model

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Hyder, Jennifer A. "An Investigation of the Effects of Increased Tidal Inundation, Competition, and Facilitation on Salt Marsh Systems." Thesis, University of South Florida, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3700275.

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<p> The low-lying topographic nature of salt marshes makes plants in these communities particularly vulnerable to increased salinity and inundation exposure associated with sea level rise. Both increased salinity and inundation have been cited as major causes of reduced plant performance and survival in marsh and areas fringing marsh. In addition to limitations imposed by physical stress, interspecific interactions have also been shown to mediate the performance and survival of salt marsh and salt marsh fringing species. The Stress Gradient Hypothesis (SGH) postulates that species interacti

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Surujon, Defne. "Computational approaches in infectious disease research: Towards improved diagnostic methods." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:109089.

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Thesis advisor: Kenneth Williams<br>Due to overuse and misuse of antibiotics, the global threat of antibiotic resistance is a growing crisis. Three critical issues surrounding antibiotic resistance are the lack of rapid testing, treatment failure, and evolution of resistance. However, with new technology facilitating data collection and powerful statistical learning advances, our understanding of the bacterial stress response to antibiotics is rapidly expanding. With a recent influx of omics data, it has become possible to develop powerful computational methods that make the best use of growin

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Penella, Casañ Consuelo. "SCREENING PEPPER GENOTYPES TO OBTAIN TOLERANT ROOTSTOCKS TO SALT AND WATER STRESS: PHYSIOLOGICAL AND AGRONOMICAL RESPONSES OF THE GRAFTED PLANTS." Doctoral thesis, Universitat Politècnica de València, 2015. http://hdl.handle.net/10251/58767.

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[EN] Pepper is a vegetable of extraordinary economic and social importance in our country. Unfortunately, the persistent exploitation of the land, the monoculture and the intensification of production processes, lead to the development of soil diseases. This coupled with the abiotic stress, mainly the salinity of waters and soil, suboptimal temperatures and water stress, can induce the appearance of physiological disorders in peppers as the Blossom-end rot (BER) and cracking or cracked, induce plant senescence and decrease not only production, but also the quality of the product. Salinity and

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Zhu, Zeyu. "Multi-Omics Stress Responses and Adaptive Evolution in Pathogenic Bacteria: From Characterization Towards Diagnostic Prediction." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:108912.

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Thesis advisor: Tim van Opijnen<br>Thesis advisor: Welkin Johnson<br>Pathogenic bacteria can experience various stress factors during an infection including antibiotics and the host immune system. Whether a pathogen will establish an infection largely depends on its survival-success while enduring these stress factors. We reasoned that the ability to predict whether a pathogen will survive under and/or adapt to a stressful condition will provide great diagnostic and prognostic value. However, it is unknown what information is needed to enable such predictions. We hypothesized that under a stre

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Salignon, Jérôme. "Genomics of fitness in periodic stress." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSEN055/document.

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Les organismes vivent dans des environnements dynamiques. Or la plupart des approches expérimentales étudient la fonction et la sélection des gènes dans des environnements statiques. De ce fait, la sélection naturelle agissant en environnements fluctuants reste mal comprise. L´objectif de mon projet a été de déterminer si certains gènes sont particulièrement importants pour la fitness (taux de croissance) de cellules de levures en environnements oscillants. Un crible génomique, basé sur une automatisation de micro-cultures et sur un multiplexage de banques de séquençage, m´a permis de mesurer

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Garland, Michael A. "Multi-stress proteomics: The global protein response to multiple environmental stressors in the porcelain crab Petrolisthes cinctipes." DigitalCommons@CalPoly, 2015. https://digitalcommons.calpoly.edu/theses/1441.

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Global climate change is increasing the number of hot days along the California coast as well as increasing the incidence of off-shore upwelling events that lower the pH of intertidal seawater; thus, intertidal organisms are experiencing an increase in more than one stress simultaneously. This study seeks to characterize the global protein response of the eurythermal porcelain crab Petrolisthes cinctipes to changes in thermal, pH, and tidal regime treatments, either combined or individually. The first experiment examined temperature stress alone and sought to determine the effect of chronic te

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Ertle, John Michael. "Effects of Short-term Chilling Stress on Seedling Quality and Post-transplanting Growth of Grafted and Nongrafted Watermelon." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1594742774066127.

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Imbert, Baptiste. "Application of translational research to the study of biological functions associated with stress resistance and adaptation to agroecological cropping systems in pulses." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2024. http://www.theses.fr/2024UBFCK085.

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L'insertion des légumineuses à graines dans les systèmes agricoles est un enjeu majeur de la transition alimentaire et écologique actuelle. En effet, ces cultures constituent une source durable de protéines et leur symbiose avec des bactéries du sol capables de fixer l'azote atmosphérique permet de réduire l’utilisation d’engrais azotés. Cependant, elles sont affectées par de nombreux stress biotiques et abiotiques impactant directement leur production, en particulier dans les systèmes agroécologiques. De nombreuses données sur la tolérance aux stress ont d'abord été acquises sur les espèces l

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Sautron, Valerie. "Biologie intégrative des réponses de stress et robustesse chez le porc." Thesis, Toulouse, INPT, 2016. http://www.theses.fr/2016INPT0086/document.

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Le travail de cette thèse s’inscrit dans le cadre du projet ANR SUSoSTRESS qui a pour objectif la compréhension des mécanismes moléculaireset génétiques sous-jacents à la variabilité individuelle de réponses de stress et a collecté des données longitudinales à plusieurs niveaux biologiquessur une population d’étude porcine (race Large White). La thèse est organisé en deux partie. La première partie s’articule autour de l’analyse de données cliniques et transcriptomiques collectées à plusieurs pas de temps avant et après application de deux types de stress : injection d’ACTH et de LPS. Dans cet

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Tyagi, Kshitiz. "A systems biology approach unravels the biological function of two tRNA wobble base modifications in fine-tuning translation and the response to environmental stress." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/32e734c5-198d-4c8a-9f56-7d5d19d1ef3d.

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tRNA molecules undergo extensive post-transcriptional modifications to produce several variations of the four canonical nucleotides. Despite the huge number of nucleotide modifications that have been identified in tRNAs, to date their biological roles and regulations continue to be poorly understood. The uridines at the wobble position of the eukaryotic cytoplasmic tRNAs tK<sup>UUU</sup>, tQ<sup>UUG</sup> and tE<sup>UUC</sup> are methoxycarbonylmethylated and thiolated to form mcm<sup>5</sup>s<sup>2</sup>U<sub>34</sub> by the <i>ELP</i>- and <i>URM1</i>-pathways, respectively. Several <i>in vi

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Tu, Nhan. "Characterization of Two Novel Gene Regulatory Systems in the Zoonotic Bacterium Bartonella henselae." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/6042.

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The genus Bartonella contains Gram-negative arthropod-borne bacteria that are found in many small animal reservoirs and are capable of causing human disease. Bacteria utilize a general stress response system to combat stresses from their surrounding environments. In α-proteobacteria, the general stress response system uses an alternate σ factor as the main regulator and incorporates it with a two-component system into a unique system. Our study identifies the general stress response system in the α-proteobacterium, Bartonella henselae, where the gene synteny is conserved and both the PhyR and

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Bourguignon, Marie. "Ecophysiological Responses of Tall Fescue Genotypes to Endophyte Infection and Climate Change." UKnowledge, 2013. http://uknowledge.uky.edu/pss_etds/28.

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Tall fescue is a widely used forage grass in the eastern USA and can form a symbiosis with a fungal endophyte, which can be beneficial for the plant but can cause livestock health issues. Little is known regarding the symbiotic response to predicted climate change. To address this knowledge gap, I analyzed tall fescue variety trial data collected throughout the U.S., exploring relationships between climate variables and yield for two different fescue cultivars that were either endophyte-free or infected. This study showed no endophyte or cultivar effect on fescue yield, but identified temperat

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Zgheib, Elias. "Bioinformatic and modelling approaches for a system-level understanding of oxidative stress toxicity." Thesis, Compiègne, 2018. http://www.theses.fr/2018COMP2464/document.

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Avec les nouvelles avancées en biologie et toxicologie, on constate de plus en plus la complexité des mécanismes et le grand nombre de voies de toxicité. Les concepts de ‘biologie systémique’ (SB) et de ‘voies des effets indésirables’ (adverse outcome pathway, AOP) pourraient être des outils appropriés pour l’étude de la toxicologie à ces niveaux de complexité élevés. Le point central du travail de cette thèse est le développement d’un modèle de SB du rôle de la voie de signalisation Nrf2 dans le contrôle du stress oxydant. Pour la calibration de ce modèle avec des données expérimentales (expo

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Lima, Daniel Chaves de. "Resposta de Chromobacterium Violaceum cultivada em alta concentra??o de ferro." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12595.

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Made available in DSpace on 2014-12-17T14:03:39Z (GMT). No. of bitstreams: 1 DanielCL_DISSERT.pdf: 3446622 bytes, checksum: 86a8ec4f8ed7a90274cc61a7f0f71422 (MD5) Previous issue date: 2012-09-25<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>The Chromobacterium violaceum is a β-proteobacterium Gram-negative widely found in tropical and subtropical regions, whose genome was sequenced in 2003 showing great metabolic versatility and biotechnological and pharmaceutical potential. Given the large number of ORFs related to iron metabolism described in the genome of C. viola

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Ratti, James A. "INVESTIGATING SMOKE EXPOSURE AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) WITH A CALIBRATED AGENT BASED MODEL (ABM) OF IN VITRO FIBROBLAST WOUND HEALING." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5441.

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COPD is characterized by tissue inflammation and impaired remodeling that suggests fibroblast maintenance of structural homeostasis is dysregulated. Thus, we performed in vitro wound healing experiments on normal and diseased human lung fibroblasts and developed an ABM of fibroblasts closing a scratched monolayer using NetLogo to evaluate differences due to COPD or cigarette smoke condensate exposure. This ABM consists of a rule-set governing the healing response, accounting for cell migration, proliferation, death, activation and senescence rates; along with the effects of heterogeneous activ

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Lavarenne, Jérémy. "Adaptation des céréales au déficit hydrique : recherche de gènes maîtres du développement racinaire par une approche de biologie des systèmes." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTG028.

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Dans cette these, nous identifions le réseau de régulation de gènes (RRG) agissant en aval de CROWN ROOTLESS1 (CRL1) et impliqué dans la formation des racines coronaires (RC) chez le riz, en vue d’identifier des gènes candidats pour moduler l’architecture du système racinaire (ASR) du riz et du maïs. Pour ce faire, nous avons généré une série temporelle transcriptomique, et l’avons utilisée pour inférer le RRG en jeu durant 45 heures après l’induction de CRL1, un intervalle couvrant les étapes précoces de l’initiation des RC. Nous avons partiellement validé ce réseau en utilisant des bases de

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Chambers, Andrea Marie. "Stressed and Strung Out: The Development and Testing of an In Vivo Like Bench-top Bioreactor for the Observation of Cells Under Shear Stress." University of Dayton / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1438218205.

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Carson, Rachel Danyetta. "Characterization of novel abiotic stress associated genes in Arabidopsis thaliana using a systems biology approach." 2008. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=772004&T=F.

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Pina, Maria Cecília Marques dos Santos Mousinho Almadanim da Câmara. "Os CPK17." Doctoral thesis, 2017. http://hdl.handle.net/10362/77052.

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"Rice is essential to feed the human population and is a key component in many food security programs. To meet the increasing food demand without further sacrificing natural areas, crop yields must be increased, which can be achieved by reducing losses due to biotic and abiotic stress conditions that compromise the production potential. Throughout evolution, plants have adapted to a diversity of new habitats, developing fascinating complex mechanisms to overcome adverse environmental conditions. The goal of this thesis was to explore rice natural genetic diversity potentially useful to

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Shortell, Robert R. "Genetic diversity of Kentucky bluegrass genotypes in morphological, agronomic, and abiotic stress tolerance characteristics." 2009. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051908.

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Molatudi, Mohohlo W. "A molecular study of y-Aminobutyric acid synthesis in Arabidopsis thaliana under abiotic stress." Thesis, 1997. http://hdl.handle.net/10413/10304.

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y-Aminonbutyric acid (GABA) is a ubiquitous non-protein amino acid found ill many plants and organisms. GABA accumulation in plants has previously been reported as result of stresses such as water deprivation, high salinity and temperature extremes. It is thought that GABA accumulates as a compatible solute in the cytoplasm where it becomes a major constituent of the free amino acid pool. GABA is synthesised from the decarboxylation of glutamate by glutamate decarboxylase (GDC). In some plants, GDC is activated by the lowering of the cytoplasmic pH and the presence of calmodulin and Ca²+ A c

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Szokoli, Franziska. "Endosymbiosis in Paramecium characterization of novel systems, transmission routes, and the influence of abiotic stress factors." 2016. https://tud.qucosa.de/id/qucosa%3A30405.

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Symbiosis between bacteria and single celled eukaryotes, such as ciliates and amoebae, is a widespread phenomenon. In the past years, the number of species characterizations of symbiotic bacteria, has constantly grown. Especially members of the order Rickettsiales (Alphaproteobacteria), which comprises obligate intracellular human and animal pathogens as well as other non-pathogenic intracellular species, got into the focus. However, biodiversity of both, protists and associated bacterial symbionts, is still largely underestimated. Thus, I hypothesised that different kind of bacteria occur nat

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BADIALI, CAMILLA. "Response of root cultures and in vitro-grown plantlets systems of Hypericum perforatum L. to biotic and abiotic stress." Doctoral thesis, 2020. http://hdl.handle.net/11573/1465947.

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Plants are sessile organisms in environments inhabited by living beings potentially dangerous to them (pathogens or phytophages) (biotic stress); moreover, they are subjected to stress caused by non-living factors depending on climate conditions (abiotic stress). For these reasons, they had to evolve specific mechanisms to detect and consequently act against complex stress combinations. In the present work, the effect of biotic and abiotic stress on Hypericum perforatum roots was evaluated, administering chitosan oligosaccharides (COS), methyl jasmonate (MeJA), salicylic acid (SA), hydrogen p

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