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Artykuły w czasopismach na temat „AC stimulation”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 1 lutego 2022

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1

Ma, Xiaofeng, and Nobuo Suga. "Augmentation of Plasticity of the Central Auditory System by the Basal Forebrain and/or Somatosensory Cortex." Journal of Neurophysiology 89, no. 1 (January 1, 2003): 90–103. http://dx.doi.org/10.1152/jn.00968.2001.

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Auditory conditioning (associative learning) or focal electric stimulation of the primary auditory cortex (AC) evokes reorganization (plasticity) of the cochleotopic (frequency) map of the inferior colliculus (IC) as well as that of the AC. The reorganization results from shifts in the best frequencies (BFs) and frequency-tuning curves of single neurons. Since the importance of the cholinergic basal forebrain for cortical plasticity and the importance of the somatosensory cortex and the corticofugal auditory system for collicular and cortical plasticity have been demonstrated, Gao and Suga pro

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2

KNISLEY, STEPHEN B. "Exploring Cardiac Response to AC Stimulation." Journal of Cardiovascular Electrophysiology 12, no. 10 (October 2001): 1185–86. http://dx.doi.org/10.1046/j.1540-8167.2001.01185.x.

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3

Su, Chen-Ying, Tzan Fang, and Hsu-Wei Fang. "Effects of Electrostatic Field on Osteoblast Cells for Bone Regeneration Applications." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/7124817.

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Many external stimulations have been shown to promote bone regeneration. The effects of an alternating current (AC) electrostatic field, one of external stimulations, generated from a device with high voltage and low current output on human osteoblastic cell line have been investigated in this study. We investigated how human osteoblasts responded to an AC electrostatic field, and the output parameters were set as 1 kV and 160 μA. Our results showed that, under such condition, the AC electrostatic field had a downregulation effect on the production ability of alkaline phosphatase and type 1 co

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4

Ma, Xiaofeng, and Nobuo Suga. "Plasticity of Bat's Central Auditory System Evoked by Focal Electric Stimulation of Auditory and/or Somatosensory Cortices." Journal of Neurophysiology 85, no. 3 (March 1, 2001): 1078–87. http://dx.doi.org/10.1152/jn.2001.85.3.1078.

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Recent findings indicate that the corticofugal system would play an important role in cortical plasticity as well as collicular plasticity. To understand the role of the corticofugal system in plasticity, therefore, we studied the amount and the time course of plasticity in the inferior colliculus (IC) and auditory cortex (AC) evoked by focal electrical stimulation of the AC and also the effect of electrical stimulation of the somatosensory cortex on the plasticity evoked by the stimulation of the AC. In adult big brown bats ( Eptesicus fuscus), we made the following major findings. 1) Electri

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5

Chaudhry, A., and J. G. Granneman. "Effect of hypothyroidism on adenylyl cyclase activity and subtype gene expression in brown adipose tissue." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 273, no. 2 (August 1, 1997): R762—R767. http://dx.doi.org/10.1152/ajpregu.1997.273.2.r762.

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Brown adipose tissue (BAT) expresses several adenylyl cyclase (AC) subtypes, and adrenergic stimulation selectively upregulates AC-III gene expression. Previous studies have described synergistic interactions between the sympathetic nervous system (SNS) and 3,5,3'-triiodothyronine (T3) on the regulation of gene expression in BAT. Because adrenergic stimulation also increases the activity of BAT type II thyroxine 5'-deiodinase (DII) and local T3 generation is important for many functional responses in BAT, we examined the effects of thyroid hormone status on the expression of various AC subtype

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6

Ward, Alex R. "Electrical Stimulation Using Kilohertz-Frequency Alternating Current." Physical Therapy 89, no. 2 (February 1, 2009): 181–90. http://dx.doi.org/10.2522/ptj.20080060.

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Transcutaneous electrical stimulation using kilohertz-frequency alternating current (AC) became popular in the 1950s with the introduction of “interferential currents,” promoted as a means of producing depth-efficient stimulation of nerve and muscle. Later, “Russian current” was adopted as a means of muscle strengthening. This article reviews some clinically relevant, laboratory-based studies that offer an insight into the mechanism of action of kilohertz-frequency AC. It provides some answers to the question: “What are the optimal stimulus parameters for eliciting forceful, yet comfortable, e

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7

Raymaekers, S., Z. Van Duppen, K. Demyttenaere, L. Luyten, L. Gabriels, B. Nuttin, and C. Bervoets. "Deep brain stimulation and anterior capsulotomy: The question of autonomy." European Psychiatry 41, S1 (April 2017): S323. http://dx.doi.org/10.1016/j.eurpsy.2017.02.249.

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IntroductionIn carefully selected treatment-refractory patients with obsessive compulsive disorder (OCD), deep brain stimulation (DBS) or anterior capsulotomy (AC) might be considered as a possible treatment. However, the direct intervention in the brain can raise questions about autonomy. Do patients still feel like they are in control of their actions when their behavior is changed by a surgical intervention?Objective/aimsTo examine in both AC and DBS patients whether these intervention influenced perception of autonomy. We aimed to discover any differences in these perceptions when comparin

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8

Ma, Xiaofeng, and Nobuo Suga. "Lateral Inhibition for Center-Surround Reorganization of the Frequency Map of Bat Auditory Cortex." Journal of Neurophysiology 92, no. 6 (December 2004): 3192–99. http://dx.doi.org/10.1152/jn.00301.2004.

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Repetitive acoustic stimulation, auditory fear conditioning, and focal electric stimulation of the auditory cortex (AC) each evoke the reorganization of the central auditory system. Our current study of the big brown bat indicates that focal electric stimulation of the AC evokes center-surround reorganization of the frequency map of the AC. In the center, the neuron's best frequencies (BFs), together with their frequency–tuning curves, shift toward the BFs of electrically stimulated cortical neurons (centripetal BF shifts). In the surround, BFs shift away from the stimulated cortical BF (centr

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9

Kiritsy, Michael. "Burst Stimulation Could Be the Next Generation of Spinal Cord Stimulation." Topics in Pain Management 31, no. 11 (June 2016): 8–9. http://dx.doi.org/10.1097/01.tpm.0000484123.86649.ac.

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10

Surikova, Ekaterina Igorevna, Elena Frantsiyants, Irina A. Goroshinskaya, Yulia A. Pogorelova, Valeria A. Bandovkina, Irina Valerevna Neskubina, Andrey A. Maslov, et al. "Does signet-ring cell carcinoma of the stomach (SRCC) need stimulation of neoangiogenesis?" Journal of Clinical Oncology 36, no. 4_suppl (February 1, 2018): 33. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.33.

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33 Background: Tumor neoangiogenesis is a complex coordinated process involving various regulatory molecules. Vascular endothelial growth factors, in particular VEGF-A, are important effectors. A multipotent TGF-β1 cytokine can modulate stromal angiogenesis reactions promoting the tumor growth. Our purpose was to study the function of the system of pro-angiogenic cytokines in tissues of stomach tumors of various histological types - adenocarcinoma (AC) and signet-ring cell carcinoma (SRCC). Methods: The concentrations of VEGF-A, VEGF-R1 and TGF-β1 were studied by ELISA in tumors, peritumoral z

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11

Cohen, Jonathan E., Chiadi U. Onyike, Virginia L. McElroy, Allison H. Lin, and Thomas W. Abrams. "Pharmacological Characterization of an Adenylyl Cyclase-Coupled 5-HT Receptor in Aplysia: Comparison With Mammalian 5-HT Receptors." Journal of Neurophysiology 89, no. 3 (March 1, 2003): 1440–55. http://dx.doi.org/10.1152/jn.01004.2002.

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We attempted to identify compounds that are effective in blocking the serotonin (5-hydroxytryptamine, 5-HT) receptor(s) that activate adenylyl cyclase (AC) in Aplysia CNS. We call this class of receptor 5-HTapAC. Eight of the 14 antagonists tested were effective against 5-HTapAC in CNS membranes with the following rank order of potency: methiothepin > metergoline ∼ fluphenazine > clozapine > cyproheptadine ∼ risperidone ∼ ritanserin > NAN-190. GR-113808, olanzapine, Ro-04-6790, RS-102221, SB-204070, and spiperone were inactive. Methiothepin completely blocked 5-HT stimulation of AC

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12

Sridharan, Arati, Sanchit Chirania, Bruce Towe, and Jit Muthuswamy. "Remote Stimulation of Sciatic Nerve Using Cuff Electrodes and Implanted Diodes." Micromachines 9, no. 11 (November 14, 2018): 595. http://dx.doi.org/10.3390/mi9110595.

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We demonstrate a method of neurostimulation using implanted, free-floating, inter-neural diodes. They are activated by volume-conducted, high frequency, alternating current (AC) fields and address the issue of instability caused by interconnect wires in chronic nerve stimulation. The aim of this study is to optimize the set of AC electrical parameters and the diode features to achieve wireless neurostimulation. Three different packaged Schottky diodes (1.5 mm, 500 µm and 220 µm feature sizes) were tested in vivo (n = 17 rats). A careful assessment of sciatic nerve activation as a function of d

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13

Li, Ying, Chao Sun, Jiujie Kuang, Changchun Ji, and Jiangtao Wu. "The Effect of Moxibustion Stimulation on Local and Distal Skin Temperature in Healthy Subjects." Evidence-Based Complementary and Alternative Medicine 2019 (April 2, 2019): 1–10. http://dx.doi.org/10.1155/2019/3185987.

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The aim of this study is to investigate the response of local and distal skin temperature to moxibustion stimulation (MS) and explore the effects of MS on sympathetic nerve activity. The distal skin temperatures of fingertips, as an indicator for sympathetic reflex response, were recorded using infrared camera during resting period (10 min), MS period (10 min), and natural cooling period (15 min), respectively. The MS without ash cleaning (AC) was applied to acupoints Quze (PC3) (Group I) and Lao Gong (PC8) (Group II), respectively. In Group III, the MS with the operation of AC was performed o

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14

Su, Tzu-Rong, Wen-Shan Zei, Ching-Chyuan Su, George Hsiao, and Min-Jon Lin. "The Effects of the KCNQ Openers Retigabine and Flupirtine on Myotonia in Mammalian Skeletal Muscle Induced by a Chloride Channel Blocker." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/803082.

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The purpose of this study was to investigate the effect of KCNQ (potassium channel, voltage-gated, KQT-like subfamily) openers in preventing myotonia caused by anthracene-9-carboxylic acid (9-AC, a chloride channel blocker). An animal model of myotonia can be elicited in murine skeletal muscle by 9-AC treatment. KCNQ openers, such as retigabine and flupirtine, can inhibit the increased twitch amplitude (0.1 Hz stimulation) and reduce the tetanic fade (20 Hz stimulations) observed in the presence of 9-AC. Furthermore, the prolonged twitch duration of skeletal muscle was also inhibited by retiga

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15

Parenti, M., D. Cocchi, G. Ceresoli, C. Marcozzi, and E. E. Müller. "Age-related changes of growth hormone secretory mechanisms in the rat pituitary gland." Journal of Endocrinology 131, no. 2 (November 1991): 251–57. http://dx.doi.org/10.1677/joe.0.1310251.

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ABSTRACT The mechanisms underlying the age-related decrease and increase in somatotroph responsiveness to growth hormone-releasing factor (GHRF) and somatostatin respectively were studied in rat pituitary membranes in vitro. Basal adenylate cyclase (AC) activity was similar in pituitary membranes from rats of 8 days (either sex) and male rats of 3 months, but it was almost threefold higher in membranes from male rats of 21–23 months. GHRF induced a lower percentage stimulation of AC activity in membranes from infant and old than adult rats. Somatostatin inhibited stimulation of AC induced by f

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16

Frings, S. "Protein kinase C sensitizes olfactory adenylate cyclase." Journal of General Physiology 101, no. 2 (February 1, 1993): 183–205. http://dx.doi.org/10.1085/jgp.101.2.183.

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Effects of neurotransmitters on cAMP-mediated signal transduction in frog olfactory receptor cells (ORCs) were studied using in situ spike recordings and radioimmunoassays. Carbachol, applied to the mucosal side of olfactory epithelium, amplified the electrical response of ORCs to cAMP-generating odorants, but did not affect unstimulated cells. A similar augmentation of odorant response was observed in the presence of phorbol dibutyrate (PDBu), an activator of protein kinase C (PKC). The electrical response to forskolin, an activator of adenylate cyclase (AC), was also enhanced by PDBu, and it

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17

Shen, Jia X., and Dermot M. F. Cooper. "AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex." Biochemical Journal 455, no. 1 (September 13, 2013): 47–56. http://dx.doi.org/10.1042/bj20130359.

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This study shows that a key signalling molecule, AC (adenylate cyclase), binds a scaffolding molecule (AKAP) which a kinase recruits which can modulate AC activity in response to stimulation of a non-canonical signalling cascade.

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18

Tsigaridas, Nikolaos, Katerina Naka, Panagiotis Tsapogas, Eleft Herios Pelechas, and Dimitrios Damigos. "Spinal cord stimulation in refractory angina. A systematic review of randomized controlled trials." Acta Cardiologica 70, no. 2 (April 2015): 233–43. http://dx.doi.org/10.1080/ac.70.2.3073516.

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19

Durr, Jacques A., Johannes Hensen, Tobias Ehnis, and Mary S. Blankenship. "Chlorpropamide upregulates antidiuretic hormone receptors and unmasks constitutive receptor signaling." American Journal of Physiology-Renal Physiology 278, no. 5 (May 1, 2000): F799—F808. http://dx.doi.org/10.1152/ajprenal.2000.278.5.f799.

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The mechanism by which chlorpropamide (CP) treatment promotes antidiuresis is unknown. CP competitively inhibited antidiuretic hormone (ADH) binding and adenylyl cyclase (AC) stimulation (inhibition constants K i and K′i of 2.8 mM and 250 μM, respectively) in the LLC-PK1 cell line. CP (333 μM) increased the apparent K a of ADH for AC activation (0.31 vs. 0.08 nM) without affecting a maximal response, suggesting competitive antagonism. Because CP lowers “basal” AC activity and the AC activation-ADH receptor occupancy relationship (A-O plots), it is an ADH inverse agonist. Twenty-four-hour CP ex

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20

Shen, T., Y. Suzuki, M. Poyard, N. Miyamoto, N. Defer, and J. Hanoune. "Expression of adenylyl cyclase mRNAs in the adult, in developing, and in the Brattleboro rat kidney." American Journal of Physiology-Cell Physiology 273, no. 1 (July 1, 1997): C323—C330. http://dx.doi.org/10.1152/ajpcell.1997.273.1.c323.

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The activity and expression of adenylyl cyclases (AC) were examined in the adult rat renal cortex and medulla. Northern blot analysis and in situ hybridization demonstrated that AC-6 was the predominant isoform in the adult rat kidney, whereas AC-4, -5, and -9 had a lower expression. AC-4 expression was higher in the cortex, and AC-5 and AC-6 were higher in the medulla. AC-9 expression was at the same level in both regions. AC activity was high in the fetus and declined in the adult. At all stages, AC activity was sensitive to parathyroid hormone, whereas no stimulation by vasopressin and isop

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21

Pepper, Joshua, Marwan Hariz, and Ludvic Zrinzo. "Deep brain stimulation versus anterior capsulotomy for obsessive-compulsive disorder: a review of the literature." Journal of Neurosurgery 122, no. 5 (May 2015): 1028–37. http://dx.doi.org/10.3171/2014.11.jns132618.

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Obsessive-compulsive disorder (OCD) is a chronic and debilitating psychiatric condition. Traditionally, anterior capsulotomy (AC) was an established procedure for treatment of patients with refractory OCD. Over recent decades, deep brain stimulation (DBS) has gained popularity. In this paper the authors review the published literature and compare the outcome of AC and DBS targeting of the area of the ventral capsule/ventral striatum (VC/VS) and nucleus accumbens (NAcc). Patients in published cases were grouped according to whether they received AC or DBS and according to their preoperative sco

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22

Ronen, Ofri, Miriam Geal-Dor, Michal Kaufmann-Yehezkely, Ronen Perez, Shai Chordekar, Cahtia Adelman, and Haim Sohmer. "Inner Ear Excitation in Normal and Postmastoidectomy Participants by Fluid Stimulation in the Absence of Air- and Bone-Conduction Mechanisms." Journal of the American Academy of Audiology 28, no. 02 (February 2017): 152–60. http://dx.doi.org/10.3766/jaaa.16036.

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Background: Hearing can be induced not only by airborne sounds (air conduction [AC]) and by the induction of skull vibrations by a bone vibrator (osseous bone conduction [BC]), but also by inducing vibrations of the soft tissues of the head, neck, and thorax. This hearing mode is called soft tissue conduction (STC) or nonosseous BC. Purpose: This study was designed to gain insight into the mechanism of STC auditory stimulation. Research Design: Fluid was applied to the external auditory canal in normal participants and to the mastoidectomy common cavity in post–radical mastoidectomy patients.

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23

Patel, Sunil, Vibhor Krishna, Joyce Nicholas, Charles M. Welzig, and Cristian Vera. "Preliminary observations on the vasomotor responses to electrical stimulation of the ventrolateral surface of the human medulla." Journal of Neurosurgery 117, no. 1 (July 2012): 150–55. http://dx.doi.org/10.3171/2012.3.jns11973.

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Object Pulsatile arterial compression (AC) of the ventrolateral medulla (VLM) is hypothesized to produce the hypertension in a subset of patients with essential hypertension. In animals, a network of subpial neuronal aggregates in the VLM has been shown to control cardiovascular functions. Although histochemically similar, neurons have been identified in the retro-olivary sulcus (ROS) of the human VLM, but their function is unclear. Methods The authors recorded cardiovascular responses to electrical stimulation at various locations along the VLM surface, including the ROS, in patients who were

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24

Geibel, J., G. Giebisch, and W. F. Boron. "Effects of acetate on luminal acidification processes in the S3 segment of the rabbit proximal tubule." American Journal of Physiology-Renal Physiology 257, no. 4 (October 1, 1989): F586—F594. http://dx.doi.org/10.1152/ajprenal.1989.257.4.f586.

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We determined that, in the nominal absence of HCO-3, acetate (Ac-) doubles luminal acidification in the S3 segment of the rabbit proximal tubule. This stimulation had two components, one that was dependent on Na+ and luminal Ac- and a second that was independent of Na+ but dependent on basolateral Ac-. In the presence of 25 mM HCO-3, Ac- did not stimulate acid secretion (i.e., HCO-3 reabsorption), but actually inhibited it. The inhibition was 35% with bilateral Ac- and 15% with basolateral Ac-. The effects of Ac- were reversible both in the absence and presence of HCO-3, and are present at con

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25

Ping, P., T. Anzai, M. Gao, and H. K. Hammond. "Adenylyl cyclase and G protein receptor kinase expression during development of heart failure." American Journal of Physiology-Heart and Circulatory Physiology 273, no. 2 (August 1, 1997): H707—H717. http://dx.doi.org/10.1152/ajpheart.1997.273.2.h707.

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We examined alterations in left ventricular (LV) G protein receptor kinase (GRK) and adenylyl cyclase (AC) isoform expression during the development of pacing-induced congestive heart failure (CHF). AC isoform and GRK expression were assessed 4 (mild CHF) and 28 (severe CHF) days after initiation of pacing. LV beta-adrenergic receptor (beta-AR) number and G protein content were unchanged by mild CHF. LV AC isoform mRNA content was unaltered by mild CHF, but there were increases in total GRK activity (P < 0.01), total GRK5 protein content (P < 0.04), and GRK5 mRNA (P = 0.003); total GRK2

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Ohbu, K., and R. A. Felder. "DA1 dopamine receptors in renal cortical collecting duct." American Journal of Physiology-Renal Physiology 261, no. 5 (November 1, 1991): F890—F895. http://dx.doi.org/10.1152/ajprenal.1991.261.5.f890.

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Renal dopamine DA1 receptors are linked to the regulation of sodium transport. We have previously reported the presence of DA1 receptors in the proximal convoluted tubule (PCT) but not in the distal convoluted tubule. However, the DA1 receptor in the collecting duct, the final determinant of electrolyte transport, has not been studied. DA1 receptors were studied in the microdissected cortical collecting duct (CCD) of rats by autoradiography with use of the selective DA1 radioligand 125I-Sch 23982 and by measurement of adenylate cyclase (AC) activity. Specific binding of 125I-Sch 23982 to CCD w

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27

Schütte, Frank, Christof Burgdorf, Gert Richardt, and Thomas Kurz. "Adenosine A1 receptor-mediated inhibition of myocardial norepinephrine release involves neither phospholipase C nor protein kinase C but does involve adenylyl cyclase." Canadian Journal of Physiology and Pharmacology 84, no. 5 (May 2006): 573–77. http://dx.doi.org/10.1139/y06-007.

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Stimulation of adenosine A1 receptors in the heart exerts cardioprotective effects by inhibiting norepinephrine (NE) release from sympathetic nerve endings. The intraneuronal signal transduction triggered by presynaptic adenosine A1 receptors is still not completely understood. The objective of the present study was to determine whether phospholipase C (PLC), protein kinase C (PKC), and adenylyl cyclase (AC) are involved in the adenosine A1 receptor-mediated inhibition of endogenous (stimulation-induced) NE release in isolated Langendorff-perfused rat hearts as an approach to elucidate their r

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28

Adelman, Cahtia, Adi Cohen, Adi Regev-Cohen, Shai Chordekar, Rachel Fraenkel, and Haim Sohmer. "Air Conduction, Bone Conduction, and Soft Tissue Conduction Audiograms in Normal Hearing and Simulated Hearing Losses." Journal of the American Academy of Audiology 26, no. 01 (January 2015): 101–8. http://dx.doi.org/10.3766/jaaa.26.1.11.

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Background: In order to differentiate between a conductive hearing loss (CHL) and a sensorineural hearing loss (SNHL) in the hearing-impaired individual, we compared thresholds to air conduction (AC) and bone conduction (BC) auditory stimulation. The presence of a gap between these thresholds (an air-bone gap) is taken as a sign of a CHL, whereas similar threshold elevations reflect an SNHL. This is based on the assumption that BC stimulation directly excites the inner ear, bypassing the middle ear. However, several of the classic mechanisms of BC stimulation such as ossicular chain inertia an

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29

Torgan, C. E., and W. E. Kraus. "Regulation of type II adenylyl cyclase mRNA in rabbit skeletal muscle by chronic motor nerve pacing." American Journal of Physiology-Endocrinology and Metabolism 271, no. 2 (August 1, 1996): E253—E260. http://dx.doi.org/10.1152/ajpendo.1996.271.2.e253.

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Skeletal muscle exhibits a wide range in functional phenotype in response to changes in physiological demands. We have observed that, in response to changes in work patterns, alterations in gene expression of some proteins coincide with changes in adenylyl cyclase (AC) activity [Kraus, W.E., J.P. Longabaugh, and S. B. Liggett. Am. J. Physiol 263 (Endocrinol. Metab. 26): E266-E230, 1992]. We now examine AC isoform transcript prevalence in various rabbit skeletal muscles and in response to changing work demands. Using reverse transcriptase-polymerase chain reaction, we detected type II AC isofor

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30

Gordeladze, J. O., I. Jynge, P. C. Borchgrevink та O. F. M. Sellevold. "Enhanced Responsiveness of the Myocardial β-Adrenoceptor-Adenylate Cyclase System in the Perfused Rat Heart (I)". Bioscience Reports 18, № 5 (1 жовтня 1998): 229–50. http://dx.doi.org/10.1023/a:1020156931565.

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Crude myocardial sarcolemmal membrane fractions were prepared from rat hearts subjected to total global ischemia with and without normoxic reperfusion, or global anoxic (N2) perfusion with and without normoxic reperfusion. The direct effects on β-adrenenoceptor number, G-protein levels and stimulation of the adenylate cyclase (AC) complex were assessed. In terms of AC activation, ischemia led to a marked increase (4-fold) in sensitivity to terbutaline (β2-agonist) and phorbol ester (tetradecanoyl phorbal acetate = TPA) stimulation, whereas the dobutamine (β1) responsiveness and Gpp(NH)p activa

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31

Yamazaki, Yoko, Masahiro Umino, Haruhisa Fukayama, and Masahiko Shimada. "The Effect of Alternating Current Iontophoresis on Rats with the Chronic Constriction Injury to the Infraorbital Nerve." International Journal of Dentistry 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/405292.

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This study aimed to examine the effect of AC iontophoresis on rats with the chronic constriction injury (CCI) to the infraorbital nerve by animal experiments. CCI model rats were divided into four groups, namely, rats that received general anesthesia for 60 min except AC IOP (CCI:n=5), AC IOP with 0.9% physiological saline for 60 min (CCI + saline AC IOP:n=5), AC IOP with 4% lidocaine hydrochloride for 60 min (CCI + lidocaine AC IOP:n=5), and attachment of two electrodes soaked with 4% lidocaine hydrochloride to the facial skin for 60 min (CCI + attach lidocaine:n=5). In the CCI + lidocaine AC

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32

Kurtz, A., J. Pfeilschifter, C. D. Brown, and C. Bauer. "NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells." American Journal of Physiology-Cell Physiology 250, no. 5 (May 1, 1986): C676—C681. http://dx.doi.org/10.1152/ajpcell.1986.250.5.c676.

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Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or not the rate of NaCl transport has an influence on PG synthesis in renal tubular cells. For our studies we used cultures of so-called high-resistance MDCK cells, which were originally derived from canine kidney. This cell type has a loop diuretic- and ouabain-sensitive NaCl transport that can be enhanced by activation of the adenylate cyclase

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JUšKA, Alfonsas, and Richard W. FARNDALE. "Inhibition of human platelet adenylate cyclase activity by adrenaline, thrombin and collagen: analysis and reinterpretation of experimental data." Biochemical Journal 340, no. 1 (May 10, 1999): 245–53. http://dx.doi.org/10.1042/bj3400245.

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Mathematical models based on the current understanding of stimulation and inhibition of adenylate cyclase (AC) activity have been developed and used to analyse experimental data [Farndale, Winkler, Martin and Barnes (1992) Biochem. J. 282, 25-32] describing the inhibition of human platelet AC by collagen, thrombin and adrenaline. Here it has been demonstrated that neither affinities of receptors specific for adrenaline or thrombin nor the activity of cAMP phosphodiesterase are affected by collagen. Both collagen and thrombin at high doses act as effective inhibitors of AC activity. Inhibition

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Trimble, R. M., and Ashraf M. El-Sayed. "Effect of certain monounsaturated dodecene and tetradecene acetates and alcohols on electroantennogram response and pheromone-mediated trap catch of the obliquebanded leafroller." Canadian Entomologist 138, no. 2 (April 2006): 218–27. http://dx.doi.org/10.4039/n05-067.

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AbstractThe effect of certain monounsaturated dodecene and tetradecene acetates and alcohols on electroantennogram (EAG) response and pheromone-mediated trap catch was examined in male obliquebanded leafroller moths, Choristoneura rosaceana (Harris) (Lepidoptera: Tortricidae). The stimulation of antennae with 0.1 ng of (Z)-11-tetradecenyl acetate (Z11-14:Ac), the major pheromone compound of this species, elicited an EAG response. The use of 1 ng of (Z)-9-tetradecenyl acetate (Z9-14:Ac) or (E)-9-tetradecenyl acetate (E9-14:Ac) or 10 ng of (Z)-9-dodecenyl acetate (Z9-12:Ac) or (E)-9-dodecenyl ac

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Geal-Dor, Miriam, Shai Chordekar, Cahtia Adelman, Michal Kaufmann-Yehezkely, and Haim Sohmer. "Audiogram in Response to Stimulation Delivered to Fluid Applied to the External Meatus." Journal of Audiology and Otology 24, no. 2 (April 10, 2020): 79–84. http://dx.doi.org/10.7874/jao.2019.00388.

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Background and Objectives: Hearing can be elicited in response to vibratory stimuli delivered to fluid in the external auditory meatus. To obtain a complete audiogram in subjects with normal hearing in response to pure tone vibratory stimuli delivered to fluid applied to the external meatus.Subjects and Methods: Pure tone vibratory stimuli in the audiometric range from 0.25 to 6.0 kHz were delivered to fluid applied to the external meatus of eight participants with normal hearing (15 dB or better) using a rod attached to a standard clinical bone vibrator. The fluid thresholds obtained were com

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Izawa, T., T. Komabayashi, T. Mochizuki, K. Suda, and M. Tsuboi. "Enhanced coupling of adenylate cyclase to lipolysis in permeabilized adipocytes from trained rats." Journal of Applied Physiology 71, no. 1 (July 1, 1991): 23–29. http://dx.doi.org/10.1152/jappl.1991.71.1.23.

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Digitonin-permeabilized adipocytes were used to study the coupling of adenylate cyclase (AC) to lipolysis in exercise-trained rats. Isoproterenol-(IPR) stimulated lipolysis in permeabilized cells was significantly greater in trained than in control rats. Under essentially identical conditions, the dose-response curve for IPR stimulation of AC activity in the absence of 3-isobutyl-1-methylxanthine was similar in trained and control rats. However, the potency of stimulation by IPR as a percentage of the basal level was greater in trained rats. AC activity and lipolysis in the presence of 3-isobu

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37

Zhang, Zhuo, Chun-Hua Liu, Yan-Qin Yu, Kenji Fujimoto, Ying-Shing Chan, and Jufang He. "Corticofugal Projection Inhibits the Auditory Thalamus Through the Thalamic Reticular Nucleus." Journal of Neurophysiology 99, no. 6 (June 2008): 2938–45. http://dx.doi.org/10.1152/jn.00002.2008.

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Electrical stimulation of the auditory cortex (AC) causes both facilitatory and inhibitory effects on the medial geniculate body (MGB). The purpose of this study was to identify the corticofugal inhibitory pathway to the MGB. We assessed two potential circuits: 1) the cortico-colliculo-thalamic circuit and 2) cortico-reticulo-thalamic one. We compared intracellular responses of MGB neurons to electrical stimulation of the AC following bilateral ablation of the inferior colliculi (IC) or thalamic reticular nucleus (TRN) in anesthetized guinea pigs. Cortical stimulation with intact TRN could cau

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Zou, H., R. R. A. Syms, S. Mellon, and K. E. Tanner. "MEMS Dielectrophoresis Device for Osteoblast Cell Stimulation." Advanced Materials Research 60-61 (January 2009): 63–67. http://dx.doi.org/10.4028/www.scientific.net/amr.60-61.63.

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A fixed microelectrode device for cell stimulation has been designed and fabricated using micro-electromechanical systems (MEMS) technology. Dielectrophoretic forces obtained from non-uniform electric fields were used for manipulating and positioning osteoblasts. The experiments show that the osteoblasts experience positive dielectrophoresis (p-DEP) when suspended in iso-osmotic culture medium and exposed to AC fields at 5 MHz frequency. This work will help to investigate the mechanisms underlying Wolff’s law of bone growth dynamics at the cellular level. The methods used can also be developed

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Doucet, A., C. Barlet-Bas, S. Siaume-Perez, C. Khadouri, and S. Marsy. "Gluco- and mineralocorticoids control adenylate cyclase in specific nephron segments." American Journal of Physiology-Renal Physiology 258, no. 4 (April 1, 1990): F812—F820. http://dx.doi.org/10.1152/ajprenal.1990.258.4.f812.

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Adrenal insufficiency is associated with an impairment of kidney diluting and concentrating ability, defects that may result from alterations of vasopressin-induced adenosine 3',5'-cyclic monophosphate (cAMP) production. The purpose of this study were 1) to localize the sites of decreased vasopressin-stimulated adenylate cyclase (AC) activity along the nephron of adrenalectomized rats; 2) to determine whether the response of AC to other hormones is altered by adrenalectomy; 3) to evaluate whether changes in AC are due to the deficiency in mineralocorticoids and/or glucocorticoids; and 4) to ch

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Zhu, Zhi-ru, Fenglian Xu, Wei-gang Ji, Shuan-cheng Ren, Fang Chen, Peng-zhi Chen, Hui-hui Jiang, et al. "Synaptic mechanisms underlying thalamic activation-induced plasticity in the rat auditory cortex." Journal of Neurophysiology 111, no. 9 (May 1, 2014): 1746–58. http://dx.doi.org/10.1152/jn.00180.2013.

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Electrical stimulation of ventral division of medial geniculate body (MGBv) neurons evokes a shift of the frequency-tuning curves of auditory cortical (AC) neurons toward the best frequency (BF) of the stimulated MGBv neurons (frequency-specific plasticity). The shift of BF is induced by inhibition of responses at the BF of the recorded AC neuron, with coincident facilitation of responses at the BF of the stimulated MGBv neuron. However, the synaptic mechanisms are not yet understood. We hypothesize that activation of thalamocortical synaptic transmission and receptor function may contribute t

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Richardson, Mark. "Deep Brain Stimulation for Locomotor Recovery Following Spinal Cord Injury." Neurosurgery 74, no. 2 (February 2014): N18—N19. http://dx.doi.org/10.1227/01.neu.0000442979.07078.ac.

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Goddard, Ayana A., Carolyn S. Pierce, and Kenneth J. McLeod. "Reversal of Lower Limb Edema by Calf Muscle Pump Stimulation." Journal of Cardiopulmonary Rehabilitation and Prevention 28, no. 3 (May 2008): 174–79. http://dx.doi.org/10.1097/01.hcr.0000320067.58599.ac.

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Martínez, C., J. Modolell, and J. Garrell. "Regulation of the proneural gene achaete by helix-loop-helix proteins." Molecular and Cellular Biology 13, no. 6 (June 1993): 3514–21. http://dx.doi.org/10.1128/mcb.13.6.3514.

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The Achaete (Ac) protein, a transcriptional regulator of the basic-helix-loop-helix (bHLH) type, confers upon ectodermal cells the ability to become neural precursors. Its temporally and spatially regulated expression, together with that of the related Scute (Sc) protein, helps define the pattern of Drosophila melanogaster sensory organs. We have examined the transcriptional control of the ac gene and shown, using in vivo assays, that several E-boxes, putative interacting sites for bHLH proteins, present in the ac promoter are most important for ac regulation. They most likely mediate ac self-

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Martínez, C., J. Modolell, and J. Garrell. "Regulation of the proneural gene achaete by helix-loop-helix proteins." Molecular and Cellular Biology 13, no. 6 (June 1993): 3514–21. http://dx.doi.org/10.1128/mcb.13.6.3514-3521.1993.

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The Achaete (Ac) protein, a transcriptional regulator of the basic-helix-loop-helix (bHLH) type, confers upon ectodermal cells the ability to become neural precursors. Its temporally and spatially regulated expression, together with that of the related Scute (Sc) protein, helps define the pattern of Drosophila melanogaster sensory organs. We have examined the transcriptional control of the ac gene and shown, using in vivo assays, that several E-boxes, putative interacting sites for bHLH proteins, present in the ac promoter are most important for ac regulation. They most likely mediate ac self-

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Farrell, Diane M., Chih-Chang Wei, José Tallaj, Jeffrey L. Ardell, J. Andrew Armour, Gilbert R. Hageman, Wayne E. Bradley, and Louis J. Dell'Italia. "Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo." American Journal of Physiology-Heart and Circulatory Physiology 281, no. 2 (August 1, 2001): H813—H822. http://dx.doi.org/10.1152/ajpheart.2001.281.2.h813.

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This study tested the hypothesis that exogenous infusion of angiotensin II (ANG II) leads to the release of catecholamines [norepinephrine (NE) and epinephrine (EPI)] into the cardiac interstitial fluid (ISF) space of dogs with adrenals intact (AI) ( n = 7) and with adrenals clamped (AC) ( n = 5). LV ISF samples were collected at 3-min intervals during administration of ANG II (100 μM ANG II at 1 ml/min for 10 min) to right atrial neurons via their local arterial blood supply and during electrical stimulation of the stellate ganglia of open-chest anesthetized dogs. In AI dogs, ANG II caused IS

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Sun, Wei, Dalian Ding, Sam Reyes, and Richard J. Salvi. "Effects of AC and DC stimulation on chinchilla SOAE amplitude and frequency." Hearing Research 150, no. 1-2 (December 2000): 137–48. http://dx.doi.org/10.1016/s0378-5955(00)00195-7.

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Debleds, S., J. P. Rebrasse, L. Dantas de Morais, I. Frapreau, R. Perdreau, and B. Morillon. "Localization of sensitive areas of power AC switch under thermal laser stimulation." Microelectronics Reliability 47, no. 9-11 (September 2007): 1569–73. http://dx.doi.org/10.1016/j.microrel.2007.07.018.

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BOND, W., and PHILIPPA J. BURCH. "Stimulation of weed seed germination by 1–(3-chlorophthalirnido) cyclohexanecarboxamide (AC 94377)." Annals of Applied Biology 116, no. 1 (February 1990): 119–30. http://dx.doi.org/10.1111/j.1744-7348.1990.tb06591.x.

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Miyagi, Yasushi, Fumio Shima, and Tomio Sasaki. "Brain shift: an error factor during implantation of deep brain stimulation electrodes." Journal of Neurosurgery 107, no. 5 (November 2007): 989–97. http://dx.doi.org/10.3171/jns-07/11/0989.

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Object The goal of this study was to focus on the tendency of brain shift during stereotactic neurosurgery and the shift's impact on the unilateral and bilateral implantation of electrodes for deep brain stimulation (DBS). Methods Eight unilateral and 10 bilateral DBS electrodes at 10 nuclei ventrales intermedii and 18 subthalamic nuclei were implanted in patients at Kaizuka Hospital with the aid of magnetic resonance (MR) imaging–guided and microelectrode-guided methods. Brain shift was assessed as changes in the 3D coordinates of the anterior and posterior commissures (AC and PC) with MR ima

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Teitelbaum, I., and T. Berl. "Increased cytosolic Ca2+ inhibits AVP-stimulated adenylyl cyclase activity in rat IMCT cells by activation of PKC." American Journal of Physiology-Renal Physiology 266, no. 3 (March 1, 1994): F486—F490. http://dx.doi.org/10.1152/ajprenal.1994.266.3.f486.

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In rat inner medullary collecting tubule (RIMCT) cells increasing cytosolic Ca2+ with a calcium ionophore inhibits arginine vasopressin (AVP)-stimulated adenylyl cyclase (AC). Inhibition by Ca2+ is not observed in pertussis toxin (PT)-treated cells, indicating a role for the inhibitory G protein, Gi. The mechanism of activation of Gi remains to be determined. We examined the hypothesis that inhibition of AVP-stimulated AC by increased cytosolic Ca2+ is due to activation of protein kinase C (PKC). Preincubation of RIMCT cells with ionophore results in inhibition of AVP-stimulated adenosine 3',5

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