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Rozprawy doktorskie na temat „Albino mice and rats”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Kamal, K. B. H. "Effects of experience and familiarity on social interactions of laboratory albino mice." Thesis, Swansea University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637750.

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The present thesis essentially applied detailed etho-logical techniques of videotaped records to assessing the impact of non-biological factors on social encounters in laboratory House mice. They generated a much more complete description of the effects of manipulations on behaviour. 'Isolated' male Swiss mice showed increased fighting after even short durations of such housing. Young mice showed more fighting after this procedure than did older animals. The grouped mice exhibited much less aggressive responsing when compared with the isolated counterparts. The age at testing for aggressive be

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2

Warren, C. E. "N-glycosylation in mice and rats." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315795.

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3

Sydorchuk, A. S., and L. I. Sydorchuk. "Microflora of the distal part of the small intestine cavity of splenectomized albino rats." Thesis, Збірник матеріалів науково-практичної конференції за участю міжнародних спеціалістів «Стратегія і тактика боротьби з інфекційними захворюваннями», присвяченої 125 - річчю Державної установи «Інститут мікробіології та імунології ім. І. І. Мечникова Національної академії медичних наук України» м.Харків, 17-18 жовтня 2012, 2012. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/5082.

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4

Armstrong, Stuart David. "The major urinary proteins of mice and rats." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526779.

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5

Todd, Dorothy A. "A study of pyretics in rats and mice." Thesis, University of Aberdeen, 1986. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU004772.

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In this study, the suitability of rodents for the detection and assay of microbial pyrogens was investigated and the pathophysiology of the 'yeast rat' model, currently used for screening antipyretic drugs, was documented. Mice do not consistently develop pyrexia following systemic injections of bacterial endotoxin (BE). These findings are in contrast to the dose-dependent hyperthermia observed in mice following intrahypothalamic injections of prostaglandin E2 (PGE2), a putative central mediator of pyrexia. Hyperthermia was associated with a decrease in skin temperature or an increase in oxyge

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6

Chandrasekar-Rao, Anjali. "Distribution and ecology of Hong Kong small mammals, with special reference to seasonality." Thesis, Hong Kong : University of Hong Kong, 1994. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17311950.

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7

Gould, Elaine M. "The molecular biology and biochemistry of resistance to rodenticides." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367721.

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8

Phillipson, Mia. "Acid transport through gastric mucus : A study in vivo in rats and mice." Doctoral thesis, Uppsala University, Department of Medical Cell Biology, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3368.

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<p>The gastric mucosa is frequently exposed to endogenously secreted hydrochloric acid of high acidity. Gastric mucosal defense mechanisms are arranged at different levels of the gastric mucosa and must work in unison to maintain its integrity. </p><p>In this thesis, several mechanisms underlying gastric mucosal resistance to strong acid were investigated in anesthetized rats and mice. The main findings were as follows:</p><p>Only when acid secretion occurred did the pH gradient in the mucus gel withstand back-diffusion of luminal acid (100 mM or 155 mM HCl), and keep the juxtamucosal pH (pH<s

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9

Sharp, Margaret. "Evaluation of DNA methods for differentiation of inbred strains of rats and mice." Thesis, Sharp, Margaret (2001) Evaluation of DNA methods for differentiation of inbred strains of rats and mice. Honours thesis, Murdoch University, 2001. https://researchrepository.murdoch.edu.au/id/eprint/41689/.

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DNA based technology offers improved differentiating methods in the laboratories of breeders of genetically uniform animals. This project examined four techniques and their application to differentiation of inbred strains of rats and mice. RAPD-PCR using 10mer primers of arbitrary sequence was evaluated as a method for differentiating strains. Although polymorphisms could be identified, it was not easy to detect these in the complex pattern produced. Attempts to simplify the pattern by reducing the level of dNTP's in the PCR reaction were unsuccessful. Restriction endonuclease digestion (i

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10

Borman, Sherri Lynn Mobley, and Sherri Lynn Mobley Borman. "Ovarian toxicity of 4-vinylcyclohexene diepoxide and polycyclic aromatic hydrocarbons in mice and rats." Diss., The University of Arizona, 1999. http://hdl.handle.net/10150/284020.

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Polycyclic aromatic hydrocarbons (PAHs) are environmental ovotoxicants commonly released in cigarette smoke and vehicle exhaust. PAHs have been shown to target small ovarian follicles (25-100 μm) after a single high dose. Once irreplaceable primordial follicles are depleted in the ovary, ovarian failure results. The occupational chemical, 4-vinylcyclohexene diepoxide (VCD), induces pre-mature ovarian failure in mice and rats. A direct comparison between the ovotoxicity caused by VCD and that of PAHs was made by calculating an initial ovotoxic index (OI = ED₅₀ x 15d) in ovarian follicles of mic

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11

Green, George A. "Studies on some aspects of the pathogenesis of Plasmodium berghei infection in mice and rats /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487684245467947.

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12

Pierce, Debra Ann. "Induction of ovotoxicity by 4-vinylcyclohexene and butadiene diepoxide in B6C3F₁ mice and F344 rats." Thesis, The University of Arizona, 2001. http://hdl.handle.net/10150/291744.

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The occupational chemicals 4-vinylcyclohexene (VCH) and butadiene diepoxide (BDE) have shown an ovarian effect in small pre-antral follicles in mice and rats (Flaws et al., 1994b; Doerr et al. , 1995). VCH exists as two enantiomers, S-VCH and R-VCH. Daily dosing with the enantiomers affected small primary follicles and wet tissue weights in B6C3F₁ mice. The S-enantiomer decreased small primary follicle numbers (P < 0.05) and both enantiomers reduced the weights of the ovary and uterus (p < 0.05). The results suggest the S-VCH enantiomer may have a greater ovotoxic effect as compared to the R-V

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13

Karper, Patrick Eugene. "Role of the Dopamine D₁-like receptor in amphetamine-induced behavioral sensitization: A study using Dopamine D₁A-receptor deficient mice." CSUSB ScholarWorks, 2000. https://scholarworks.lib.csusb.edu/etd-project/1682.

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The ability of the indirect dopamine agonist, amphetamine, to produce behavioral sensitization was assessed in adult D₁A-deficient and wild-type mice. It was originally predicted that : 1) dopamine (DA) D₁-like receptors are necessary for the occurrence of short- and long-term amphetamine-induced behavioral sensitization, 2) DA D₁-like receptors are necessary for environmental conditioning factors associated with amphetamine-induced behavioral sensitiazation, and 3) DA D₅ receptors are required for amphetamine-induced behavioral sensitization. Locomotor activity and sterotyped sniffing were as

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14

張朝雄 and Chiu-hung Cheung. "Molecular cloning and characterization of mouse testin complementary DNA." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31220563.

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15

Benmaamar, Ramla. "Role of neuropeptide Y and its receptors in the development of epileptogenesis in mice and rats." Université Louis Pasteur (Strasbourg) (1971-2008), 2003. http://www.theses.fr/2003STR13007.

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16

Takagishi, Yoshiko, Kouichi Hashimoto, Tetsuro Kayahara, et al. "Diminished climing fiber innervation of Purkinje cells in the cerebellum of myosin Va mutant mice and rats." Wiley, 2007. http://hdl.handle.net/2237/7904.

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17

Hasan, S. A. "Videotape analysis of the involvement of sex steroids in the social interactions in laboratory mice and rats." Thesis, Swansea University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637237.

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Ethoexperimental techniques were applied to reassess sex steroid influences on social encounters in laboratory rodents. Parallel investigations on Lister Hooded rats and TO strain albino mice were completed, with treatments being applied to individually-housed rodents. Same-sex rats and mice were paired in combinations here a) both members were surgically-manipulated/injected with active material, b) both rodents were sham-operated/injected with control solutions or c) the subjects were treated differently. All three kinds of pairing were videotaped (60 and 10 minutes for rats and mice, respec

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18

Kong, Wing-cheung Billy, and 江詠璋. "Age-related physiological and pathological changes in the regulation of endothelium-dependent relaxations in mice and rats." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46917305.

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19

Loonat, Firdows. "Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta Graveolens L. in mice and rats." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/4379.

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Magister Pharmaceuticae - MPharm<br>Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta graveolens L. in mice and rats FIRDOWS LOONAT M. Pharm. Pharmaceutical Sciences thesis: School of Pharmacy, University of the Western Cape Ruta graveolens (Rutaceae) L. is a medicinal plant that is commonly used to manage and treat essential events such as pain, inflammation and fever. Despite its popularity, particularly as a medicinal plant in the Calvinia district and Bredasdorp region of South Africa, scientific data to substantiate its widespread traditional use and

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20

Dockery, P. "Ultrastructural abnormalities of myelinated fibres in the peripheral nerves of streptozotocin induced diabetic rats and genetically diabetic (db/db) mice." Thesis, University of Aberdeen, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377611.

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Qualitative and quantitative ultrastructural observations have been made on myelinated fibres in the tibial and medial plantar nerves of genetically diabetic C57/BL/Ks(db/db) and age-matched nondiabetic (m/m) control mice at 9 and 15 months of age. The cross sectional area of myelinated fibres and their axons in both nerves was found to be significantly less in diabetic mice when compared with age-matched controls. No age related decrease in axon or fibre size was noted in the diabetic at either site. The number of myelin lamellae was found to be proportionate for axon size in the tibial nerve

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21

Li, Yuk-yin. "Adrenomedullin in the rat reproductive systems and the changes of the gene expression of adrenomedullin and its receptor components during ageing." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/HKUTO/record/B3955692X.

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22

Bahamonde, Azcuy Javiera del Pilar. "Short- and Long-Term Effects of Commercially Available Gold Nanoparticles in Rodents." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/54572.

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Gold nanoparticles (GNPs) are currently being intensely investigated for their potential use in biomedical applications. Nanotoxicity studies are urgently needed to validate their safety in clinical practice. The objective of this research was to assess the acute, subacute, and chronic effects of a single intravenous exposure to commercially available GNPs in two in vivo models, mice and rats. Gold nanoparticles were purchased and independently characterized. Animals were exposed to either 1000 mg GNPs/kg body weight (GNP group) or an equivalent volume of phosphate buffered saline (PBS group)

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23

Henriksnäs, Johanna. "Helicobacter pylori and Gastric Protection Mechanisms : An in vivo Study in Mice and Rats." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk cellbiologi, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5898.

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The stomach is frequently exposed to hazardous agents and to resist this harsh environment, several protective mechanisms exist. Of special interest is the gastric pathogen Helicobacter pylori which causes gastritis, ulcers and cancer but the mechanism leading to these diseases are still unclear. However it is very likely that H. pylori negatively influence the protection mechanisms that exist in the stomach. The aims of the present investigation were first to develop an in vivo mouse model in which different protection mechanisms could be studied, and second to investigate the influence of H

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24

Jing, Yan 1975. "Effects of pressurization on the digestibility and glutathione inducing property of whey protein isolates in rats and mice." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84100.

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Hydrostatic pressure has been demonstrated to induce major changes in secondary structure of whey proteins resulting in an increased digestibility in vitro, and possibly an improvement of the glutathione (GSH) inducing effect of whey proteins in vivo. Micro filtration and ion-exchange, two commonly used processing techniques in whey protein manufacture, generate whey proteins with different compositions. Two animal studies were designed to compare the digestibility and GSH inducing effects of whey protein isolates (WPIs) treated with three repeated pulse cycling of pressure (3-cycle) or

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25

Makley, Meghan Katherine. "NMR analyses show TCDD elicits differences in hepatic metabolism in female C57BL/6 mice and Sprague-Dawley rats." Wright State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=wright1230048333.

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Wassermann, Laura [Verfasser], Andre [Akademischer Betreuer] Bleich, and Christine [Akademischer Betreuer] Häger. "Telemetry-based severity assessment after surgical interventions in mice, rats, and sheep / Laura Wassermann ; Andre Bleich, Christine Häger." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2020. http://d-nb.info/1218073535/34.

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Salyers, Kevin Lyndon. "Disposition and metabolism of 4-vinyl-1-cyclohexene diepoxide in female Fischer 344 rats and B6C3F(1) mice." Diss., The University of Arizona, 1995. http://hdl.handle.net/10150/187076.

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4-Vinyl-1-cyclohexene diepoxide (VCD) is a known carcinogen, a direct acting mutagen, and an ovarian toxicant. Female B6C3F₁ mice are more susceptible to the ovarian toxicity of VCD than female Fischer 344 rats, a difference which may be explained by the disposition/metabolism of VCD. Following a single dose ¹⁴C-VCD was rapidly metabolized and excreted predominantly in the urine of both species. However, the excretion rate was higher in the female rats compared to female mice. The major metabolite present in rat urine was the 4-(1,2-dihydroxy) ethyl-1,2-dihydroxycyclohexane (tetrol). However,

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張曉暉 and Xiaohui Zhang. "Analysis of nitric oxide generation in various organs of animal modelsduring ischemia-reperfusion." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B3122216X.

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Zhang, Xiaohui. "Analysis of nitric oxide generation in various organs of animal models during ischemia-reperfusion /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21185426.

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Yuan, Jing Ting (Christine). "Sex Differences in Oxytocin and Vasopressin V1a Receptor Binding Densities in the Mouse Brain: Focus on the Social Behavior Neural Network." Thesis, Boston College, 2017. http://hdl.handle.net/2345/bc-ir:107419.

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Thesis advisor: Alexa Veenema<br>Thesis advisor: Nicholas Worley<br>Oxytocin (OT) and vasopressin (AVP) often regulate social behaviors in sex-specific ways. We hypothesized that this could be mediated by sex differences in the OT receptor (OTR) and AVP V1a receptor (V1aR) in the brain. Here, we determined whether there are sex differences in OTR and V1aR binding densities in nodes of the social behavior neural network in the mouse brain. We also compared sex differences int he OTR and V1aR in the mouse brain with those found previously in the rat brain. Although mice and rats are closely rela

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31

Janczyk, Pawel [Verfasser]. "Evaluation of nutritional value and activity of green microalgae Chlorella vulgaris in rats and mice / vorgelegt von Pawel Janczyk." Berlin : Mensch-und-Buch-Verl, 2006. http://d-nb.info/979243254/34.

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Lemoine, Alexandra. "The influence of environmental hypoxia in the physiological responses of laboratory rats and mice during postnatal life and adulthood." Doctoral thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/26665.

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Il existe chez les différentes espèces de rongeurs une importante variabilité dans les capacités à établir des colonies stables en haute altitude (HA). Par exemple, on trouve des souris (Mus) jusqu'à 4000m alors qu’il n’y a pas de rats (Rattus). La capacité des animaux à survivre et réaliser des activités physiques en HA dépend d’adaptations biologiques physiologiques (plasticité phénotypique) et génétiques ou épigénétiques. Des rats Sprague Dawley (SD) maintenus en HA dans des conditions de laboratoire survivent pendant plusieurs générations (La Paz, Bolivia – 3600m) mais présentent des signe

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33

李玉賢 and Yuk-yin Li. "Adrenomedullin in the rat reproductive systems and the changes of the gene expression of adrenomedullin and its receptor components duringageing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B3955692X.

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Fakurazi, Sharida. "The formation of hepatic protein adducts in the livers of rats and mice treated with non steroidal anti inflammatory drugs." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250712.

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Borecky, Lisa. "Hypoxia-inducible factor-1α and the Control of Hypoxic Ventilatory and Metabolic Responses in Mice and African Naked Mole Rats". Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37908.

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Hypoxia-inducible factors (HIFs) are a highly conserved group of transcriptional regulators responsible for cellular and systemic O2 homeostasis in animals. However, how HIFs are involved in basic adaptive ventilatory and metabolic responses to acute and chronic hypoxia remains incompletely characterized. Naked mole rats are among the most hypoxia tolerant mammals identified. As opposed to the typical hyperventilatory response of most adult mammals, naked mole rats exhibit a unique decline in ventilation, matching their substantial decrease in metabolic rate. Naked mole rats therefore provide

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36

Costanzo, Vincenzo <1990&gt. "In vivo evaluation of renal function using intravital multiphoton microscopy on rats and mice with induced or spontaneous renal injury." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9926/1/costanzo_vincenzo_tesi.pdf.

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Multiphoton microscopy is a powerful tool for the in vivo imaging of renal processes thanks to the improved tissue penetration and the high spatial and temporal resolution. Intravital imaging permits to evaluate dynamic processes and pathophysiological parameters in real time using non-invasive methods. This project aims to use existing multiphoton microscopy approaches to evaluate in vivo many renal parameters in our animal models and, at the same time, to develop an original application for the assessment of single nephron glomerular filtration rate. In addition, a method for detection and q

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Giblin, Kathryn Anne. "Is epilepsy a preventable disorder? New evidence from animal models." Yale University, 2010. http://ymtdl.med.yale.edu/theses/available/etd-03052010-144943/.

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Epilepsy accounts for 0.5% of the global burden of disease, and primary prevention of epilepsy represents one of the three 2007 NINDS Epilepsy Research Benchmarks. Efforts to understand and intervene in the process of epileptogenesis have yielded fruitful preventative strategies in animal models. This article reviews the current understanding of epileptogenesis, introduces the concept of a "critical period" for epileptogenesis, and examines strategies for epilepsy prevention in animal models of both acquired and genetic epilepsies. As proof of principle, we investigated whether early preventat

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38

Jacquet, Benoit Victor. "A comparative study of terminal disruption after partial denervation in slow- and fast-twitch muscles of neonatal CFP mice and Wistar rats." NCSU, 2005. http://www.lib.ncsu.edu/theses/available/etd-07132005-180536/.

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After partial denervation of mature muscle, the remaining motoneurons grow terminal sprouts, which reinnervate denervated muscle fibers. In neonatal rat soleus muscle however, not only do the remaining motoneurons fail to reinnervate nearby muscle fibers, but they also display clear morphological and physiological evidence of terminal disruption. My ultimate aim is to attain a better understanding of this disruption by performing repeated in vivo observations of individually identified terminals in transgenic mice expressing fluorescent proteins in their motoneurons. For technical reasons, the

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Bäckberg, Matilda. "Hypothalamic neuronal circuits involved in the regulation of food intake and body weight : histochemical studies in lean rats and obese mutant mice /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-794-0/.

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Monteiro, Karin Maia 1971. "Avaliação toxicologica e farmacologica do complemento nutricional "TK3"." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309826.

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Orientadores: João Ernesto de Carvalho, Ana Lucia Tasca Gois Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-09T11:07:54Z (GMT). No. of bitstreams: 1 Monteiro_KarinMaia_M.pdf: 2254231 bytes, checksum: 20b2ee4f5d5aaf0109e94552d1fec08d (MD5) Previous issue date: 2006<br>Resumo: O complemento nutricional ¿TK3¿ foi inicialmente estudado por um bioquímico alemão, Sr. Friedrich Lavitcshka, que desenvolveu uma formulação em 1969, inicialmente líquida, constituída basicamente pela associação de triptofano e timi

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41

Johnson, Allan Michael. "Distribution of lithium in untreated and lithium supplemented rats and mice : relevance to the potential use of lithium in the treatment of AIDS." Thesis, University of Wolverhampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338358.

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Ngomuo, Ahmed Juma. "Genotoxicity studies of the bracken fern constituents quercetin, shikimate and ptaquiloside in vitro in salmonella typhimurium and in vivo in rats and mice." Thesis, University of Surrey, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317326.

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McCaffery, Brian. "Studies of the roles of metabotropic glutamate receptors in synaptic transmission and plasticity in the perirhinal and hippocampal cortices of mice and rats." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300562.

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Agnelli, Silvia. "Regulation of amino acid catabolism in rats fed diets with different protein content." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/400005.

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Current lifestyle with high-energy diets and characterized by sedentary is triggering an alarming growth in obesity. Obesity along with metabolic syndrome- related co-morbidities (i.e. insulin resistance, atherosclerosis, sleep apnea, depression, asthma, hypertension and the alteration of blood lipid transport) are the most apparent consequence of the excess energy. Under conditions of excess dietary energy, the body cannot easily dispose of the excess amino-N against the evolutively-adapted schemes that prevent its wastage; thus ammonia and glutamine formation and urea excretion are decreased

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45

Li, Qiang [Verfasser], Harun [Akademischer Betreuer] Palar, Johannes Georg [Akademischer Betreuer] Filser, and M. [Akademischer Betreuer] Coelhan. "In Vitro Toxicokinetics of Ethylene and Ethylene Oxide in Mice, Rats, and Humans / Qiang Li. Gutachter: Johannes Georg Filser ; M. Coelhan. Betreuer: Harun Palar." München : Universitätsbibliothek der TU München, 2012. http://d-nb.info/1025150368/34.

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Pettersson, Ulrika. "Blood Flow Regulation and Inflammatory Response in Experimental Models of Diabetes." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk cellbiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-161807.

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Type 2 diabetes is caused by defect pancreatic islet β-cells together with peripheral insulin resistance. The disease is often accompanied by obesity with associated low-grade visceral adipose tissue inflammation, which contributes to insulin resistance. As a consequence of, and a possible compensation for the increased insulin demand, blood flow to the pancreatic islets is increased in animal models of diabetes. This increased blood perfusion might with time affect the vascular network as well as β-cells within the islets. This thesis investigates the role of changes of blood perfusion in pan

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Lamperti, Edward D. "Characterization of the Gene and Messages for Vasoactive Intestinal Polypeptide in Rat and Mouse: a Thesis." eScholarship@UMMS, 1989. http://escholarship.umassmed.edu/gsbs_diss/233.

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The organization and transcription of the gene for vasoactive intestinal polypeptide (VIP) in rats and mice was investigated using northern- and Southern-blot hybridizations, selective genomic cloning, Sl-nuclease protection assays, oligonucleotide-directed RNase H digestions, and genomic cloning by standard methods. The center of the rat VIP gene and the entire mouse gene were cloned and sequenced. Selective genomic cloning was used to isolate a strongly-hybridizing fragment of the rat VIP gene identified in Southern-blot hybridizations with an existing human VIP cDNA. This fragment

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Snow, Dallin R. "Dietary Milk Fat Globule Membrane Reduces the Incidence of Aberrant Crypt Foci in Fischer-344 Rats and Provides Protections Against Gastrointestinal Stress in Mice Treated with Lipopolysaccharide." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/831.

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Milk fat globule membrane surrounds the fat droplets of milk. It is a biopolymer containing primarily membrane glycoproteins and polar lipids which contribute to its properties as a possible neutraceutical. The aims of the studies were to determine if dietary milk fat globule membrane: (1) confers protection against colon carcinogenesis; and (2) promotes gut mucosal integrity while decreasing inflammation compared to diets containing corn oil or anhydrous milk fat. Aim 1. Three dietary treatments differing only in the fat source were formulated: (1) AIN-76A, corn oil; (2) AIN-76A, anhydrous mi

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Deliwe, Mzonke. "Pharmacological evaluation of antidiarrhoeal and antidiabetic activities of Syzygium Cordatum Hochst. ex C. Krauss." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_9985_1351170857.

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Syzygium cordatum is a medicinal plant indigenous to South Africa and Mozambique, commonly used to treat stomach aches, diabetes, respiratory problems and tuberculosis. In spite of the folklore use, adequate scientific data to credit its widespread traditional use is lacking. The objectives of this study were: to evaluate and validate scientifically the successful therapeutic claims by traditional medicine practitioners that Syzygium cordatum is effective in treating diarrhoea and diabetes<br>to determine the effects of the plant extract on gastrointestinal transit of a charcoal meal in mice<b

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May, Ulrike [Verfasser]. "Role of IL-6 trans-signalling for sleep-wake behaviour of rats : generation of brain-specific sgp130-Fc transgenic mice ; central blockade of IL-6 trans-signalling / Ulrike May." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1020003863/34.

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