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Artykuły w czasopismach na temat „Albino mice and rats”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

SUNDAR, S. T. BINO, T. J. HARIKRISHNAN, BHASKARAN RAVI LATHA, et al. "Prevalence of syphaciosis in laboratory rodents with emphasis on species identification, treatment and Th2 cytokine response." Indian Journal of Animal Sciences 88, no. 7 (2018): 765–70. http://dx.doi.org/10.56093/ijans.v88i7.81404.

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Prevalence of syphaciosis (pinworm infection) in laboratory rats and mice, species identification, chemotherapy with ivermectin and its effect on pinworm infection, and Th2 cytokine response was studied. Using perianal tape test examination, the highest rate of pinworm infection was found in male Wistar rats (69.44%) followed by female Wistar rats (62.50%), male Balb C mice (60.60%), female Swiss Albino mice (51.42%), male Swiss Albino mice (33.33%) and female Balb C mice (32.69%). Wistar rats had maximum infection (65.97%) followed by Balb C mice (46.64%) and Swiss albino mice (42.37%). Overa

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Ngongeh, L.A, I.W Onyenwe, D.A Oche, G.A Musongong, and B.B. Fakae. "PREVALENCE OF CESTODE INFECTIONS IN ALBINO MICE AND RATST EASTERN: A PUBLIC HEALTH THREAT." Continental J. Animal and Veterinary Research 3, no. 2 (2011): 16–20. https://doi.org/10.5281/zenodo.818060.

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Cestode infections are known to be common in man and rodents all over the world. Cestodes of rodents (<em>Hymenolepis spp</em>) are also known to infect man. The number of mice and rats used for experimental studies are on the increase. The prevalence of cestode infections in albino mice and rats in Michael Okpara University of agriculture, Umudike and University of Nigeria, Nsukka and their environs was investigated. Faeces were collected from 350 albino mice and rats each and screened for the presence of cestode eggs by flotation and McMaster techniques. Sixty six percent and fifty percent o

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3

Allam, Ahmed A., and Rasha E. Abo‐Eleneen. "The development of sensorimotor reflexes in albino mice; albino rats and black‐hooded rats." International Journal of Developmental Neuroscience 30, no. 7 (2012): 545–53. http://dx.doi.org/10.1016/j.ijdevneu.2012.08.005.

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ABDEL-KADER, MOHAMED R., ABDELMAWGOD A. ASRAN, AHMED A. AL-GENDY, and KAMAL E. KALEAL. "FOOD PREFERENCE FOR ALBINO RATS AND ALBINO MICE UNDER LABORATORY CONDITIONS." Egyptian Journal of Agricultural Research 92, no. 4 (2014): 1279–90. http://dx.doi.org/10.21608/ejar.2014.156762.

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Gammal, Alaa. "Comparative Study on the Gross Anatomy of Some Abdominal Organs in Albino Rat (Rattus norvegicus) and Albino Mouse (Mus musculus)." Alexandria Journal of Veterinary Sciences 80, no. 1 (2024): 1. http://dx.doi.org/10.5455/ajvs.183386.

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A comparative gross anatomical study was carried out on six apparently healthy adult male albino rats (Rattus norvegicus) and albino mice (Mus musculus) (Three rats and three mice) The aim of the current work is to demonstrate the gross anatomical topography, morphology and fixation of (liver, kidney, spleen, stomach and pancreas) in order to highlight similarities and differences between both species. The animals were brought from local animal markets and delivered to the anatomy laboratory of the Faculty of Veterinary Medicine Cairo University, Egypt. After euthanasia, animals were anatomica

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6

Green, Daniel G., Pilar Herreros De Tejada, and Marilyn J. Glover. "Electrophysiological estimates of visual sensitivity in albino and pigmented mice." Visual Neuroscience 11, no. 5 (1994): 919–25. http://dx.doi.org/10.1017/s0952523800003874.

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AbstractWe have estimated the absolute threshold of congenic albino and pigmented mice (C57) using ERG, pupillary light reflex, and VHP. We are unable to detect strain differences using ERGs or VEPs, but pupillary thresholds appear to be different. In addition, as we have previously reported for rats, VEP thresholds are considerably lower than the ERG b−wave thresholds. The VEP thresholds agree with behavioral data from pigmented mice made by others. The mouse VEP thresholds are close to the VEP thresholds in rats and the psychophysical thresholds of two human observers.

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Baidya, Moushumi, Anbu Jayaraman, Himangshu Sekhar Maji, Ramya Krishna P S, and Dibya Das. "Evaluation of acute and sub-acute toxicity of sivanar amirtham in albino mice and wistar albino rats." Journal of medical pharmaceutical and allied sciences 11, no. 1 (2022): 4196–204. http://dx.doi.org/10.55522/jmpas.v11i1.2217.

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The objective of present study is to evaluate the acute and sub-acute toxicity of Sivanar Amirtham in Swiss albino mice and Wistar albino rats. A single dose of extract (2000 mg/kg) was given orally to the animals in the acute study, and they were observed for 14 days. In the sub-acute investigation, biochemical, haematological, and histological parameters were assessed after successive doses of Sivanar Amirtham (100, 200, and 400 mg/kg/day) were given for 28 days. After a single or repeated dosage of Sivanar Amirtham, there was no evidence of toxicity or mortality. Sivanar Amirtham median let

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8

Saxena, J. K., S. Khare, A. K. Srivastava, A. B. Sen, and S. Ghatak. "Hepatic acid hydrolases of albino rats,Mastomys natalensis and albino mice duringPlasmodium berghei infection." Experientia 41, no. 4 (1985): 472–74. http://dx.doi.org/10.1007/bf01966153.

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Santosh Kumar, Rada, and Sahithi Mudili. "ACUTE AND SUB-ACUTE TOXICITY STUDIES OF STARCH GLUTAMATE - A NOVEL SUPERDISINTEGRANT." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 307–10. http://dx.doi.org/10.22270/jddt.v9i4.3163.

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Starch glutamate was a novel superdisintegrant which was synthesized from the native potato starch and glutamic acid by esterification process. The prepared starch glutamate toxicity was evaluated by performing acute and sub-acute toxicity studies on the Wister rats and Swiss albino mice. Acute toxicity studies were conducted on the Swiss albino mice by dividing them randomly into 10 groups (6 rats in each group) and treated with starch glutamate up to the concentration of 2000mg/Kg body weight, and then they were closely observed for 12 hrs for any toxic symptoms. Sub –acute toxicity studies

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10

Balkema, Grant W., and Ursula C. Dräger. "Impaired visual thresholds in hypopigmented animals." Visual Neuroscience 6, no. 6 (1991): 577–85. http://dx.doi.org/10.1017/s095252380000256x.

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AbstractOcular hypopigmentation is associated with neurological defects in structure and function. This paper investigates the ab/Fute visual thresholds in dark-adapted hypopigmented animals compared to their normally pigmented controls. Here we asked (1) whether the threshold elevation found in hypopigmented animals is a general consequence of the reduction in melanin content; (2) if so, which melanin components in the eye are likely to influence visual thresholds; and (3) whether similar threshold defects can be detected in orders other than rodents. By single-unit recordings from the superi

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11

Pramestuti, Nova, Corry Laura Junita Sianturi, Eva Lestari, and Siwi Pratama Mars Wijayanti. "EFEK RODENTISIDA NABATI PAPAIN PEPAYA (CARICA PAPAYA L.) TERHADAP PERUBAHAN HISTOPATOLOGI ORGAN MENCIT ALBINO." Kesmas Indonesia 11, no. 2 (2019): 178. http://dx.doi.org/10.20884/1.ki.2019.11.2.1636.

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Reports on the rodenticide effect of papain papaya to control rats and mice is scarce. The aim of this study was to determine pathological changes in albino mice internal organs (gaster, kidney, liver and intestine) associated with toxicity effect of papain papaya (Carica papaya L.). Seventy-eight adult BALB/c mice of both sexes were divided into 5 groups: 1 control group and 4 treatment groups that were given papain feeding block. Feed intake and mortalities have been monitored in previous study. At the end of the experimental period, tissues of mice were harvested for necropsy and histopatho

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12

Shahatha, S. S., M. O. Mousa, I. M. Ayyed, et al. "Effect of Alcoholic Extract of the Plant Conyza bonariensis on the Parasite Hymenolepis nana in Albino Mice Infected with it Experimentally." IOP Conference Series: Earth and Environmental Science 1325, no. 1 (2024): 012026. http://dx.doi.org/10.1088/1755-1315/1325/1/012026.

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Abstract This study was conducted to investigate the effect of an alcoholic extract of the Mountain grass plant Conyza bonariensis on adults of the dwarf tapeworm Hymenolepis nana in albino mice infected with it experimentally, where Albino mice of the strain Balb/C were infected with these worms experimentally, it was divided into 5 groups, each group consisting of 6 rats, where the first group (control) was given distilled water only. As for the other groups, they were dosed with different concentrations of the alcoholic extract of the plant 50, 100, and 200 mg/kg, The last group was given 1

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13

Panchal, Radhika, and Nutanbala N. Goswami. "Evaluation of antidepressant activity of hydro-alcoholic extract of rhizomes of Nardostachys jatamansi DC per se and in combination with fluoxetine in wistar albino rats and swiss albino mice." International Journal of Basic & Clinical Pharmacology 9, no. 1 (2019): 32. http://dx.doi.org/10.18203/2319-2003.ijbcp20195761.

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Background: Depression is a common mental disorder results due to deficiency of neurotransmitter in the brain. Various medicinal properties of jatamansi are mentioned in Ayurveda. This study evaluated effect of hydro-alcoholic extract of rhizomes of Nordostachys jatamansi DC per se and in combination with fluoxetine in wistar albino rats and swiss albino mice.Methods: Animals of either sex were selected and randomly divided in test group. Jatamansi extract 10:1 and fluoxetine hydrochloride dissolved in distilled water were used. Animals were tested for forced swimming test, tail suspension tes

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Pandey, Alok, R. Rajavel, Sandeep Chandraker, and Deepak Dash. "Synthesis of Schiff Bases of 2-amino-5-aryl-1,3,4-thiadiazole and Its Analgesic, Anti-Inflammatory and Anti-Bacterial Activity." E-Journal of Chemistry 9, no. 4 (2012): 2524–31. http://dx.doi.org/10.1155/2012/145028.

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Schiff Bases of 2-amino-5-aryl-1,3,4-thiadiazole derivatives have been synthesized with different aromatic aldehyde. 1,3,4-thiadiazole derivatives were prepared by the reaction of thiosemicarbazide, sodium acetate and aromatic aldehyde. The structures of the titled Schiff bases were elucidated by IR and1H NMR spectral measurements. All the compounds were evaluated for their analgesic activity against swiss albino mice, anti-inflammatory activity against Wister albino rats. The compounds showed significant antibacterial activity againstStaphylococcus aureus(gram-positive) bacteria andE. coli(gr

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15

Hayes, Jennifer M., and Grant W. Balkema. "Visual thresholds in mice: Comparison of retinal light damage and hypopigmentation." Visual Neuroscience 10, no. 5 (1993): 931–38. http://dx.doi.org/10.1017/s0952523800006143.

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AbstractIn previous electrophysiological experiments from hypopigmented animals (mice, rats, rabbits), single-unit recordings from both retinal ganglion axons and cells in the superior colliculus have demonstrated an increase in threshold in the dark-adapted state which is roughly proportional to the animal's ocular melanin concentration. We have examined the thresholds in hypopigmented mice by using a behavioral water maze screening test and found similar threshold elevations to the electrophysiology. In the present study, we investigated the contribution of retinal light damage to the thresh

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16

Rabo, J. S., A. B. Wakil, and H. C. C. Maduka. "EFFECTS OF BERENIL ON THE PATHOGENESIS OF TRYPANOSOMIASIS IN Trypanosoma brucei INFECTED RATS." Nigerian Journal of Animal Production 21 (January 3, 2021): 142–45. http://dx.doi.org/10.51791/njap.v21i1.1165.

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Ten Albino rats were each infected intraperitoneally with 0.5 million Trypanosoma strain 8/18 organisms. Cerebral lesions were absent in all rats and mice injected with brain tissue and choroid plexus homogenates from group A rats were aparasitaemic over anobservation period of 30 days. However, infected rats developed intermittent (parasitaemia, lost weight progressively and became anaemic with death intervening in one case. We conclude that T. bricci strain 8/18 infection in rats produces moderate to severe disease which may lead to death; but the organism is is not pushed across the blood-b

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Grigoryan, Lilit N., Yuliya V. Bataeva, and Yuliya V. Bataeva, Jamilya M. Bratilova. "SAFETY STUDY OF ACTINOBACTERIA OF THE GENUS STREPTOMYCES FOR COMPLIANCE WITH INDUSTRIAL MICROORGANISMS FOR AGRICULTURAL PURPOSE." Problems of veterinary sanitation, hygiene and ecology 1, no. 45 (2023): 84–88. http://dx.doi.org/10.36871/vet.san.hyg.ecol.202301012.

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The safety of the Streptomyces carpaticus RCAM04697 strain on daphnia (Daphnia magna Straus), albino rats and albino mice was assessed for compliance with industrial microorganisms for agricultural purposes. Studies have shown that the suspension and aqueous solutions of the S. carpaticus RCAM04697 strain do not have a depressing effect on the survival of D. magna individuals, which allows them to be classified as non-toxic substances for aquatic organisms. In terms of virulence, dissemination, toxicity and toxigenicity, the S. carpaticus RCAM04697 strain is not pathogenic for warm-blooded ani

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Fatma Hassan Boshahma, Ali H. Mahmoud Masoud, Nisreen Hassan Alferjani, et al. "Olive Oil's protective potential against cyclophosphamide-induced nephrotoxicity in Swiss albino rats." Open Access Research Journal of Life Sciences 8, no. 2 (2024): 001–7. http://dx.doi.org/10.53022/oarjls.2024.8.2.0031.

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Background: Cyclophosphamide is a widely used chemotherapy drug, known for its cytotoxic and mutagenic effects on mammalian tissues and cells. Olive oil, rich in antioxidants, has potential protective effects against drug-induced organ damage. This study investigates the protective role of olive oil against cyclophosphamide-induced toxicity in mice. Objective: To evaluate the protective effects of olive oil against cyclophosphamide-induced kidney toxicity in rats. Material and Method: Male albino mice (n=9) were divided into three groups: Control, Cyclophosphamide (150 mg/kg), and Cyclophospha

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Menezes, Cylma, Kunal G, Reema N, Satyanarayana D, and Jagadish K. "Analgesic and Anti-inflammatory Activity of Ficus glomerata in Experimental Animal Models." International Journal of Pharmaceutical Sciences and Nanotechnology 4, no. 3 (2011): 1501–5. http://dx.doi.org/10.37285/ijpsn.2011.4.3.10.

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 The anti-inflammatory and analgesic activity of various extracts of Ficus glomerata Roxb. were evaluated in experimental animals. We have determined the anti-inflammatory and analgesic activity of various extracts of the dried fruits of Ficus glomerata by oral administration at doses of 200 and 400 mg/kg of body weight to healthy animals. The extracts were studied for their anti-inflammatory activity in carageenan induced hind paw edema in rats and the paw volume was measured plethysmometrically after 3 hours of injection. The extracts were also evaluated for analgesic activity using Ed

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Revathi, Sundaramoorthy, V. Gopal, and G. Jeyabalan. "ACUTE TOXICITY AND IN-VIVO LAXATIVE STUDIES OF THE TRIPHALA EXTRACT IN EXPERIMENTAL ANIMALS." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 341–47. http://dx.doi.org/10.22270/jddt.v9i4.3170.

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Triphala has been extensively used in traditional medicine for laxative, antidiabetic, expectorant, astringent, anti-aging etc. The acute toxicity of methanolic extracts of Triphala in 300 mg, 600 mg, and 1000 mg/kg has not yet been studied. The current studies were done by employing Swiss Albino mice as experimental animal. The methanolic extracts of Triphala were considered safe up to a dose of 1000 mg/kg when evaluated for acute oral toxicity in accordance with the OECD (Organization for Economic Cooperation and Development) guidelines. The results of acute toxicity showed no signs of toxic

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Kapgate, Sarita M., and Abhijit B. Patil. "STANDARDIZATION OF MODEL OF INDUCTION OF HEPATOTOXICITY WITH ANTI-TUBERCULOSIS DRUGS IN WISTAR ALBINO RATS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 6 (2017): 150. http://dx.doi.org/10.22159/ajpcr.2017.v10i6.11971.

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Objective: The objective of the study to standardize the model of hepatotoxicity induced by ATT drugs in Wistar Albino rats. Isoniazid (INH), rifampicin (RMP), pyrazinamide (PZA), the first line drugs used in the treatment of tuberculosis (TB) associated with the potential adverse effect. Numerous animal studies were reported endeavoring induction and cure of anti-TB (ATT) drug-induced hepatotoxicity using herbal and chemical drugs. However, the previous reported study failed to replicate where Wistar albino rats were treated with INH, RMP, and PZA and had shown the significant development of

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Goswami, Praveen, Shilpi Damor, and Utkarsh Kaushik. "Mitigating of Paracetamol-induced Hepatotoxicity in Albino Mice Using Boerhaavia diffusa Extracts." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 15 (2024): 103–9. http://dx.doi.org/10.56557/upjoz/2024/v45i154225.

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Boerhaavia diffusa, renowned for its therapeutic efficacy in chronic liver diseases, operates through multifaceted mechanisms to uphold internal homeostasis. Its pivotal roles encompass modulation of intermediary metabolism of macromolecules, synthesis of crucial plasma proteins, enzymatic activities, and bile excretion.In this investigation, we aimed to evaluate the hepatoprotective potential of Boerhaavia diffusa against paracetamol-induced hepatotoxicity in rats. Our study revealed promising outcomes as the extracts obtained from Boerhaavia diffusa demonstrated a significant hepatoprotectiv

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Sidhoum, Rekia, Mostapha Bachir bey, Latifa Halli, Othmane Yalaoui, and Asma Belkadi. "Phenolic profile, Anti-inflammatory and Diuretic properties of Asplenium ceterach tested on Albino mice and Wistar albino rats." Asian Journal Of Research in Chemistry 13, no. 6 (2020): 449–54. http://dx.doi.org/10.5958/0974-4150.2020.00080.2.

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Raju, Sama, Narra Venkata Subbaiah, Kandukuri Sreeramulu Reddy, Amit Das, and Krishnan Bala Murugan. "Potential of Pandanus odoratissimus as a CNS depressant in Swiss albino mice." Brazilian Journal of Pharmaceutical Sciences 47, no. 3 (2011): 629–34. http://dx.doi.org/10.1590/s1984-82502011000300022.

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In this study, several neuropharmacological effects of methanolic leaf extract of Pandanus odoratissimus (PO) (family; Pandanaceae) were studied in albino mice using various experimental models. The effect of PO on the CNS was studied by using different neuropharmacological paradigms including spontaneous motor activity, rota-rod performance and potentiation of Pentobarbital sodium sleeping time in albino mice. Preliminary phytochemical evaluation and acute toxicity studies were also carried out where LD50 >2000 mg/kg was considered non-toxic through acute exposure in rats by the oral route

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Aby Mathew Jose and Akhila Vinod. "An experimental evaluation of Anti-Inflammatory and Analgesic Activity of Allium Cepa Linn. and Allium Ascalonicum Linn. - A comparative study." Journal of Ayurveda and Integrated Medical Sciences 9, no. 5 (2024): 35–39. http://dx.doi.org/10.21760/jaims.9.5.7.

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Introduction: The drugs possessing Vataghna property are much indicated in classics for managing Shotha and Vedana. Cost-effective, widely available, and potent drugs should be encouraged over costly ones. The present study was undertaken based on this, focusing on the bulb of Allium cepa Linn. & Allium ascalonicum Linn. to evaluate the anti-inflammatory and analgesic activities employing carrageenan induced paw oedema in wistar albino rats and hotplate tests in mice, respectively. Materials and Methods: Fresh juice of Allium cepa Linn. and Allium ascaloncum Linn. was given to rats and mic

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Putri, Tetra Anestasia. "PENGARUH PEMBERIAN BISPENOL-A (BPA) TERHADAP JUMLAH SPERMATOZOA PADA Rattus norvegicus GALUR WISTAR ALBINO." JURNAL KESEHATAN PERINTIS (Perintis's Health Journal) 6, no. 1 (2019): 9–13. http://dx.doi.org/10.33653/jkp.v6i1.210.

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Bispenol-a (BPA) has an esterogen hormone activity while it enters the body, it can become endocrine disruptor. The objetive of this study was to purpose to prove that bispenol a can decrease spermatozoa cell count in male wistar albino strain rats (rattus novergicus).This research is an experimental design with post-only control group by using 20 male wistar albino strain rats (rattus Novergicus). Those sample aged 2-3 months which divided into four groups for 5 rats each. Control group (K) without bispenol-a adduction. The first (P1), second (P2), and third (P3) group treatment was given wit

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Nmezi, S. N., M. C. Nwachukwu, and M. C. Igbomezie. "Effects Of A. Congensis Extract On Heamatology Of Albino Rat." European Journal of Medical and Health Sciences 4, no. 1 (2022): 93–96. http://dx.doi.org/10.24018/ejmed.2022.4.1.1083.

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Purpose: The study was conducted to investigate the possible effects of Alstonia congensis (leaf, bark and root) extracts on heamatology of albino rat. Is the extract poisonous? What is the LD50 of the extract? Is the heamatology of the test animals affected by the extract? Is the effect dangerous for the animal? Method: The study was carried out between February 2019 to October 2020. A. congensis was collected from Emekuku area of Imo State. The albino rats were purchased from the Animal Science and Production Department of Michael Okpara University of Agriculture, Umudike, Umuahia. Acute tox

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Uche Emmanuel Olunkwa, Kizito Munachiso Enyereibenyem Iheanacho, Chidi Uzoma Igwe, and Linus Ahuwaraeze Nwaogu. "Lactation suppression effect of aqueous seed extract of Aframomum melengueta on female albino rats." International Journal of Biological and Pharmaceutical Sciences Archive 7, no. 1 (2024): 101–14. http://dx.doi.org/10.53771/ijbpsa.2024.7.1.0024.

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Background and aims: Alligator pepper, a dietary spice used as food flavor enhancer is a common ingredient in pepper soup, a spicy delight in most parts of West Africa and possesses both medicinal and nutritive properties. Despite the well documented benefits of breastfeeding for mothers and infants, there are a variety of medical situations for which breastfeeding is contraindicated. Therefore, lactation suppression might be indicated for the best interest of the mother and/or infant. This study was undertaken to investigate the Lactation suppression effect of aqueous seed extract of Aframomu

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Chinnasamy, Velmurugan, Vetriselvan Subramaniyan, Sarath Chandiran, et al. "Antiarthritic Activity of Achyranthes Aspera on Formaldehyde - Induced Arthritis in Rats." Open Access Macedonian Journal of Medical Sciences 7, no. 17 (2019): 2709–14. http://dx.doi.org/10.3889/oamjms.2019.559.

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AIM: To determine the ameliorative potential of aqueous extract of Achyranthesaspera(AEAA) against arthritis using swiss albino mice and Wistar rats, and its possible mechanism of action. METHODS: Swiss albino mice (25-30 g) and Wistar rats (150-180 g) under standard controlled conditions (24 ± 2°C, 50-70 humidity and 12 h light/dark cycle). The groups were divided into 6 groups (n = 6/group) and assigned as control, negative control, standard and, formaldehyde supplemented with two different test dose groups of A. aspera for 4 weeks. Arthritis induced by subplantar administration of 0.1

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Onyeabo, Chimaraoke, and Polycarp Nnacheta. "Toxicological implications of Margaritaria discoidea aqueous seed extract on Na+, K+-ATPase specific activity, glucose and serum electrolytes level in wistar rats." International Journal of Pharmacology and Toxicology 4, no. 2 (2016): 210. http://dx.doi.org/10.14419/ijpt.v4i2.6660.

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The effect of aqueous seed extract of Margaritaria discoidea on Na+ K+ ATPase activity and toxicity studies of its seed extract were investigated in albino rats. The study involved oral administration of different doses of the aqueous extract to groups of male albino rats at 25, 50,100, and 200mg/kg body weight resulted in significant (p<0.05) decrease in sodium, potassium and glucose levels while chloride and calcium ions showed a significant (p<0.05) increase relative to control. The seed extract also showed significant (p<0.05) decrease in Na+ K+ ATPase specific activity in a dose

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Ande, Shailaja, Khadar Shaik, Ravi Dharmoji, Nisa Firdouse, Anjum Mohd, and Sowmya Yelwarthi. "Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities." International Journal of Pharmacology and Toxicology 4, no. 2 (2016): 111. http://dx.doi.org/10.14419/ijpt.v4i2.6123.

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Oxazine heterocyclic compound containing one oxygen and one nitrogen atom. They possess different pharmacological activities like anticancer, anti-ulcer, antifungal, antithrombotic, antihypertensive, analgesic, anti-inflammatory etc. Oxazine Sulphonamide derivatives were investigated for anti-inflammatory, analgesic and anti-pyretic activities. It was evaluated for anti-inflammatory activity by carrageenan induced paw edema in rats using Plethysmometer and it also shows significant analgesic effect in male Albino mice. Antipyretic activity was also investigated.

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Joy Ogugua Igwe, Harrison Odera Abone, Moses Chukwuemeka Ezea, Chika Peter Ejikeugwu, and Charles Okechukwu Esimone. "Acute and chronic toxicity evaluation of methanol leaf extract of Psidium guajava (Myrtaceae)." GSC Biological and Pharmaceutical Sciences 16, no. 3 (2021): 120–28. http://dx.doi.org/10.30574/gscbps.2021.16.3.0270.

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The medicinal value of herbal plants have been widely described in a number of studies, this has resulted in their increased usage. This study aimed to evaluate the safety of methanolic leaf extract of Psidium guajava extract in albino rats using biochemical, hematological and histological parameters. In acute toxicity, the extract was administered orally up to 5,000 mg/kg body weight once to male albino mice. While in chronic toxicity, twenty four adult male albino rats were randomly divided into four groups of six rats for each group. The control group received 10 ml/kg body weight distilled

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Joy, Ogugua Igwe, Odera Abone Harrison, Chukwuemeka Ezea Moses, Peter Ejikeugwu Chika, and Okechukwu Esimone Charles. "Acute and chronic toxicity evaluation of methanol leaf extract of Psidium guajava (Myrtaceae)." GSC Biological and Pharmaceutical Sciences 16, no. 3 (2021): 120–28. https://doi.org/10.5281/zenodo.5542915.

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The medicinal value of herbal plants have been widely described in a number of studies, this has resulted in their increased usage. This study aimed to evaluate the safety of methanolic leaf extract of <em>Psidium guajava</em> extract in albino rats using biochemical, hematological and histological parameters. In acute toxicity, the extract was administered orally up to 5,000 mg/kg body weight once to male albino mice. While in chronic toxicity, twenty four adult male albino rats were randomly divided into four groups of six rats for each group. The control group received 10 ml/kg bo

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Sonu and Chauhan Renu. "The Effect of Cypermethrin on the Fertility Index of Adult Albino Rats." International Journal of Pharmaceutical and Clinical Research 15, no. 2 (2023): 988–95. https://doi.org/10.5281/zenodo.12823594.

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<strong>Background:</strong> When given orally to male mice, cypermethrin significantly increased the weights of the testicles, seminal vesicles, prostate gland, and epididymis. Interstitial edoema, vacuolation in the early stages of the germ cell layer, thickening of the basal membrane, Leydig cell atrophy and Sertoli cells with dense residual bodies were all visible under the microscope in the testicular tissue that had been exposed to cypermethrin. <strong>Aim:</strong> This study was conducted to analyze the effect of cypermethrin on thé fertility index of adult albin

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BALKEMA, GRANT W., and SHANNON MacDONALD. "Increased absolute light sensitivity in Himalayan mice with cold-induced ocular pigmentation." Visual Neuroscience 15, no. 5 (1998): 841–49. http://dx.doi.org/10.1017/s0952523898155062.

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Controversy over the relationship between ocular pigmentation and absolute dark-adapted light sensitivity has persisted for over two decades. Previous electrophysiological experiments in hypopigmented mammals (mice, rats, rabbits) show increased thresholds in the dark-adapted state proportional to the deficit in ocular melanin. Animals with the least amount of ocular melanin have the most elevated thresholds. Dark-adapted thresholds in hypopigmented mice show similar threshold elevations in behavioral tests. The present study extends these findings to show that a specific increase in ocular pi

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Salema Lafta Hassan, Sura Ayed Radam, and Bushra Ibrahim Mustafa. "Toxopathological and Biochemical Impacts of Albino Mice Treated with Lanxess." Academic International Journal of Veterinary Medicine 3, no. 1 (2025): 35–43. https://doi.org/10.59675/v315.

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Background: Lanxess (1,3-benzene dicarboxylic acid) is a safe food ingredient found in various foods and soft drinks. On the other hand, it has antifungal and antibacterial activity and is employed in the management of certain medical disorders. Additionally, it acts as an antioxidant, anti-ozonant, and anti-degradant, protecting vulcanizates against damaging external influences. This research aims to estimate the toxicity of Lanxess in the liver by measuring alkaline phosphatase (ALP) and alanine aminotransferase (AST) levels.Materials and Methods: 20 albino mice were subdivided into two grou

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Samia Elzwi. "Analgesic and Anti- Inflammatory Effect of Zingiber Officinale in Albino Mice." Scientific Journal of University of Benghazi 33, no. 1 (2020): 5. http://dx.doi.org/10.37376/sjuob.v33i1.297.

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Zingiber officinale (ginger) is common part of the diet in many parts of the world, Recent research has found ginger to have various pharmacological properties due to a variety of active constituents, including shogoals and gingerols. It is a member of zingiberaceae family originated in Southeast Asia and has been introduced to many parts of the globe where it proliferates in suitable environment. Ginger contain constituents with anti-inflammatory properties. The fresh and dried ginger both contains active 6 – gingerol and gingerdion along with other resinous pungent principle, extracted with

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Omoirri MA, Madubogwu NU, Iloh SE, Adejumo SA, and Ojiako CM. "Renal architectural changes in Plasmodium berghei inoculated mice." GSC Biological and Pharmaceutical Sciences 13, no. 3 (2020): 222–27. http://dx.doi.org/10.30574/gscbps.2020.13.3.0409.

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Plasmodium falciparum (P. falciparum) is a specie of Plasmodium parasite responsible for the pathogenicity of malaria, a disease with several complications reported as the leading cause of over 1 million deaths worldwide. In this study, the effects of malaria on the kidney (Renal) histo-architecture was studied ex-vivo in albino mice rats. Twenty one (21) albino mice rats of between 30 – 35g weights were procured, acclimatized for two weeks in the animal unit of the Ambrose Alli University, Ekpoma, Edo State. They were then grouped into three (3) of seven (7) mice each, following which group I

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Omoirri, MA, NU Madubogwu, SE Iloh, SA Adejumo, and CM Ojiako. "Renal architectural changes in Plasmodium berghei inoculated mice." GSC Biological and Pharmaceutical Sciences 13, no. 3 (2020): 222–27. https://doi.org/10.5281/zenodo.4415234.

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<em>Plasmodium falciparum </em>(<em>P. falciparum</em>) is a specie of <em>Plasmodium</em> parasite responsible for the pathogenicity of malaria, a disease with several complications reported as the leading cause of over 1 million deaths worldwide. In this study, the effects of malaria on the kidney (Renal) histo-architecture was studied ex-vivo in albino mice rats. Twenty one (21) albino mice rats of between 30 – 35g weights were procured, acclimatized for two weeks in the animal unit of the Ambrose Alli University, Ekpoma, Edo State. They were then grouped into three (3)

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Madhuri, D., and Vardhani V. Viveka. "GST level in the abdominal muscles of mice treated with Immunex DS and GeneVac B vaccine." Biolife 3, no. 1 (2022): 26–30. https://doi.org/10.5281/zenodo.7262881.

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<strong>ABSTRACT</strong> The effect of immunostimulant, Immunex DS (IDS) and Gen Vac B vaccine was tested against GST in the abdominal muscle of male Swiss albino mice (6 - 8 weeks old; 23 - 26g wt) at different days of experiment. Six groups of experimental mice (A, B, C, D, E and F), one control group (U) and another IDS treated group (I) were selected. IDS was orally administered @ 150mg/mouse on 0 day (group I). To all the mice of groups A to F, IDS was orally administered (@ 150mg/mouse) on 0 day and Gen Vac B vaccine was inoculated on day 4 of experiment (0.07 ml/mouse in group A, 0.1ml

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Surwase, Ulhas Shrimant, and Shivanand Malkappa Patil. "SCREENING FOR ANALGESIC AND ANTI INFLAMMATORY ACTIVITIES OF ETHANOLIC EXTRACT OF JUSTICIA GENDARUSSA BURM LEAVES." Journal of Advanced Scientific Research 13, no. 03 (2022): 141–45. http://dx.doi.org/10.55218/jasr.202213322.

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Ethanol extract of the leaves of Justicia gendarussa Burm was subjected to analgesic and anti-inflammatory activities in animal models. Albino Wistar rats and mice were the experimental animals respectively. Different CNS depressant paradigms like analgesic (determined via Eddy's hot plate approach and acetic acid writhing approach) and antiinflammatory activity (determined via carrageenan induced paw edema using plethysmometer in albino rats) were carried out, following the intra-peritoneal administration of ethanol extract of formulation Justicia gendarussa Burm leaves (EEJG) at the dose lev

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Sinha, Chaitali, and Girja S. Shukla. "Species variation in pesticide-induced blood-brain barrier dysfunction." Human & Experimental Toxicology 22, no. 12 (2003): 647–52. http://dx.doi.org/10.1191/0960327103ht405oa.

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Neurological disorders following acute or chronic exposure to pesticides have been reported in a number of human cases. However, the mechanism(s) by which pesticides produce central nervous system dysfunction is not clear. The objective of the present study was to examine the functional status of blood-brain barrier (BBB) in rats and mice exposed to selected pesticides of different chemical groups. Adult male albino rats and mice were exposed (1/10 of LD50) daily to dichlorvos (organophosphate), lindane (organochlorine) and carbofuran (carbamate) through oral intubation for 3 days. The status

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ABDEL-RAHIM, Emam, Hossam S. EL-BELTAGI, Rehab F. M. ALI, Abeer A. AMER, and Somia M. MOUSA. "The Effects of Using Synthetic and Natural Color Foods on Lipid Profile and Liver Function in Rats." Notulae Scientia Biologicae 11, no. 4 (2019): 363–67. http://dx.doi.org/10.15835/nsb11410504.

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Today synthetic food dyes are being used most commonly as food colorant in confectionaries for children. Present study was designed to evaluate effect of tartrazine and chocolate brown as a synthetic color and turmeric, cocoa as a natural color on Swiss albino mice. The rats have been fed on color biscuits and after the acclimation period, rats were divided into 7 groups (5 rats each one). Rats treated with dose level 7.5 mg/kg /day (ADI) in tartrazine and turmeric and 0.15 mg/kg /day (ADI) in chocolate brown and cocoa. The study revealed a highly noticeable decrease in the body weight gain, f

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Jasmin, Gold V., and Vardhani V. Viveka. "Changes in testicular DNA in mice against immunostimulation and hepatitis." Biolife 5, no. 1 (2022): 33–37. https://doi.org/10.5281/zenodo.7356735.

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<strong>ABSTRACT</strong> Male swiss albino mice were treated with immunostimulant (@ 150 mg/mouse) (group I), and immunostimulant (@ 150 mg/mouse) + antigen (@ 0.007 ml to 1 ml) (groups A to F).   One group (N) of mice was kept as controls (untreated) for comparison.  Estimation of testicular DNA was done on day 1,2,3,4 and 5 (on day 11 to 15 of experimental design) of experimental period after immunostimulation and/or antigenation.  Mice treated with immunostimulant alone showed significant increase of testicular DNA when compared with controls.  However, experimenta

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Anosike, Chizoba J., Emenike B. Amadi, Parker E. Joshua, Rita O. Asomadu, and Jachike R. Aneke. "Evaluation of Analgesic Potential of Shumanniophyton magnificum Extract on Albino Rats." Nigerian Journal of Biochemistry and Molecular Biology 39, no. 3 (2024): 141–45. https://doi.org/10.4314/njbmb.v39i3.4.

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Shumaniophyton magnificum is usually used in African folk medication to treat various diseases, especially fever, malaria, and pain. Pain is a well-known indicator of illness, and the medications used to treat pain are called analgesics. The primary issue with these medications continues to be their side effects. Natural herbs are safer substitutes. This study explored the analgesic potentials of the methanol extract of S. magnificum leaf using three distinct in vivo analgesic models: the Acetic Acid-Induced Writhing, Hot Plate, and Tail Flick Response Assessments. When compared to aspirin-tre

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Raymond, Michel, and Jean-Marie Bergeron. "Sélection des proies par l'hermine en captivité." Canadian Journal of Zoology 64, no. 9 (1986): 1973–80. http://dx.doi.org/10.1139/z86-297.

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Certain aspects of prey selection were studied in ermines (Mustela erminea) kept in an enclosed arena that simulated a temporary meadow. Four males and eight females were involved in the 12-h experiments. Four types of prey were used: (i) meadow voles (Microtus pennsylvanicus), (ii) deer mice (Peromyscus maniculatus), (iii) short-tailed shrews (Blarina brevicauda), and (iv) young albino rats (Rattus norvegicus). Males were more efficient at catching prey than females, both in number of individuals and number of species captured. Meadow voles and rats were the prey captured most regularly and r

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Herve, Tchoumbou Tadjoua, Ateufack Gilbert, Laure Matafack Dongmo Olivette, et al. "Oral Acute and Sub-Chronic Toxicity Studies of the Aqueous and Methanol Leaves Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Balb/c Mice and Wistar Rats." International Journal of Toxicological and Pharmacological Research 10, no. 1 (2018): 10–24. https://doi.org/10.5281/zenodo.12679900.

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In Africa, especially in Cameroon, the aqueous extract of the leaves of <em>Dissotis thollonii</em> has been used as folk medicine for thousands of years for the diarrhoeal and inflammatory diseases. However, there is no scientific evidence to verify the safety of its use. The aim of this study was to evaluate the toxicological potential of <em>Dissotis thollonii</em> through the acute and sub-chronic toxicity tests. Acute and sub-chronic toxicity studies with <em>Dissotis thollonii</em> was done on Balb/c mice and wistar albino rats respectively. Anthropometric,

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Uysal, Murat, Serdar Savaş Gül, Serhat Karaman, et al. "Caecum location in laboratory rats and mice: an anatomical and radiological study." Laboratory Animals 51, no. 3 (2016): 245–55. http://dx.doi.org/10.1177/0023677216658916.

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Intraperitoneal (i.p.) injection is the most frequently used method for implementing parenteral therapies in rats and mice. Whether the caecum is located in the right caudal quadrant or left caudal quadrant in the abdominal cavity is not clear. For that reason, we have developed a method for identifying the location of the caecum in rats and mice and thus revealed the most reliable location for i.p. injection in these animals. Two hundred Wistar albino rats and 100 BALB/c mice were used. The location of the caecum was determined by revealing the intra-abdominal organs immediately following eut

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Abbood, Alaa Saadi, Anwer Jaber Faisal, and Mokhtar jawad Al-Imam. "Effect of Artemisia Vulgaris on Liver of Albino Mice Exposed to Cisplatin." Biomedical and Pharmacology Journal 17, no. 2 (2024): 1341–46. http://dx.doi.org/10.13005/bpj/2948.

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The herb Arte(also known as Artemisia V.) is widely used to treat a variety of illnesses, including gastrointestinal disorders, infections, and fungal infections. The antibacterial component that makes this ingredient so beneficial and essential for treating septicemia is the prebiotic. This study looked at how Artemisia vulgaris L. protected rats' livers from the toxic treatment cisplatin. In virtual medicine, cisplatin is frequently employed. Numerous forms of human cancer, such as advanced cancer, uterine cancer, esophageal cancer, advanced privacy, and ovarian cancer, have been successfull

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Mani, Vellingiri Manon, Arockiam Jeyasundar Parimala Gnana Soundari, Balamuralikrishnan Balasubramanian, et al. "Evaluation of Dimer of Epicatechin from an Endophytic Fungus Curvularia australiensis FC2AP on Acute Toxicity Levels, Anti-Inflammatory and Anti-Cervical Cancer Activity in Animal Models." Molecules 26, no. 3 (2021): 654. http://dx.doi.org/10.3390/molecules26030654.

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Cervical cancer, as the most frequent cancer in women globally and accounts almost 14% in India. It can be prevented or treated with vaccines, radiation, chemotherapy, and brachytherapy. The chemotherapeutic agents cause adverse post effects by the destruction of the neighboring normal cells or altering the properties of the cells. In order to reduce the severity of the side effects caused by the chemically synthesized therapeutic agents, the current research developed an anti-cancer agent dimer of epicatechin (DoE), a natural bioactive secondary metabolite (BSM) mediated from an endophytic fu

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