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Artykuły w czasopismach na temat „Albino mice”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Brown, Robert T. "Exercise Demonstrating a Genetic-Environment Interaction." Teaching of Psychology 16, no. 3 (1989): 131–32. http://dx.doi.org/10.1207/s15328023top1603_7.

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Using inexpensive equipment and a limited number of subjects, this exercise demonstrates, through a factorial design, an interaction between genetics and environment. It also provides experience in direct observation of behavior. Inbred albino and pigmented mice are individually observed in a bright or dim open field; students record activity and defecation. Under dim light, albino and pigmented mice both show high levels of activity; under bright light, the activity of albino mice is suppressed but that of pigmented mice is little affected. Albinos defecate more than pigmented under both ligh

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2

Guillery, R. W., G. Jeffery, and B. M. Cattanach. "Abnormally high variability in the uncrossed retinofugal pathway of mice with albino mosaicism." Development 101, no. 4 (1987): 857–67. http://dx.doi.org/10.1242/dev.101.4.857.

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Female mice showing albino mosaicism due to an X-autosome translocation [Is(In7;X)Ct] have been studied in order to investigate the relationship between the distribution of melanin and the formation, early in development, of the abnormally small uncrossed retinofugal pathway characteristically found in all albino mammals. Earlier evidence indicates that cells normally bearing melanin play a role in producing the abnormality. In the mosaic mice, the albino gene is expressed in only about half of the cells due to random X-inactivation and the patches of normal and albino cells are extremely smal

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3

Vohra, Prerna, and Navneet Kumar Gupta. "Carbontetrachloride induced toxicity in liver of albino mice." Indian Journal of Applied Research 3, no. 9 (2011): 273–75. http://dx.doi.org/10.15373/2249555x/sept2013/80.

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4

Gillani, Q., M. Ali, and F. Iqbal. "CGP 35348, GABABReceptor Antagonist, Has a Potential to Improve Neuromuscular Coordination and Spatial Learning in Albino Mouse following Neonatal Brain Damage." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/295215.

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To study the effect of CGP 35348 on learning and memory in albino mice following hypoxia ischemia insult, 10 days old albino mice were subjected to right common carotid artery ligation followed by 8% hypoxia for 25 minutes. Following brain damage, mice were fed on normal rodent diet till they were 13 week old. At this time point, mice were divided into two groups. Group 1 received saline and group 2 intrapertoneally CGP 35348 (1 mg/mL solvent/Kg body weight) for 12 days. A battery of tests used to assess long term neurofunction (Morris water maze, Rota rod and open field) along with brain infa

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5

VICENTE TEJEDOR, J., L. RAMIREZ, C. TORETS, S. CARRALERO, P. DE LA VILLA, and C. SANCHEZ-RAMOS. "Visual capacity in albino mice. Are albino mice good for every neuroscience’s experiment?" Acta Ophthalmologica 90 (August 6, 2012): 0. http://dx.doi.org/10.1111/j.1755-3768.2012.f065.x.

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6

DALY, GERARD H., JESSICA M. DILEONARDO, NATALIE R. BALKEMA, and GRANT W. BALKEMA. "The relationship between ambient lighting conditions, absolute dark-adapted thresholds, and rhodopsin in black and hypopigmented mice." Visual Neuroscience 21, no. 6 (2004): 925–34. http://dx.doi.org/10.1017/s0952523804216121.

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Significant variation in absolute dark-adapted thresholds is observed both within and between strains of mice with differing ocular pigmentation levels. Differences in threshold within a single strain are related to the Williams' photostasis effect, that is, photoreceptor rhodopsin levels are dependent upon ambient lighting conditions. To examine threshold differences among strains, we equalized rhodopsin levels by maintaining albino mice (c2J/c2J) at 2 × 10−4 cd/m2 (dim light) and black mice at 2 × 102 cd/m2 (bright light). This resulted in ocular rhodopsin levels for albino mice (albino—dim)

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7

Ekelund, MC, R. Carstam, C. Hansson, H. Rorsman, and E. Rosengren. "Urinary excretion of 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid: differences between pigmented and albino mice." Acta Dermato-Venereologica 65, no. 5 (1985): 437–39. http://dx.doi.org/10.2340/0001555565437439.

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Urinary excretion of the phaeomelanin precursor 5-S-cysteinyldopa (5-S-CD) and the eumelanin metabolite 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI-2-C) was studied in black and albino mice. The urinary concentration of 5-S-CD was 31.7 ng/ml in black and 16.1 ng/ml in albino mice. The concentration of 6H5MI-2-C was 21.0 ng/ml in the urine of black mice. The compound could not be demonstrated in the urine of albino mice.

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8

Taubitz, Tatjana, Alexander V. Tschulakow, Marina Tikhonovich, et al. "Ultrastructural alterations in the retinal pigment epithelium and photoreceptors of a Stargardt patient and three Stargardt mouse models: indication for the central role of RPE melanin in oxidative stress." PeerJ 6 (July 19, 2018): e5215. http://dx.doi.org/10.7717/peerj.5215.

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Background Stargardt disease (SD) is characterized by the accumulation of the age-pigment lipofuscin in the retinal pigment epithelium (RPE) and subsequent neuroretinal degeneration. The disease leads to vision loss early in life. Here, we investigate age-dependent ultrastructural changes in three SD mouse models: albino Abca4-/- and pigmented Abca4-/- and Abca4-/-.Rdh8-/- mice. Since we found indications for oxidative stress primarily in albino SD mice, we tested RPE melanin for its antioxidative capabilities. Methods SD mouse eyes were investigated by light, fluorescence and electron microsc

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9

Kelsey, Gavin, and Günther Schütz. "Lessons from lethal albino mice." Current Opinion in Genetics & Development 3, no. 2 (1993): 259–64. http://dx.doi.org/10.1016/0959-437x(93)90032-k.

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10

Diniz, Daniel G., Jhonnathan H. P. de Oliveira, Luma C. F. Guerreiro, et al. "Contrasting Disease Progression, Microglia Reactivity, Tolerance, and Resistance to Toxoplasma gondii Infection in Two Mouse Strains." Biomedicines 12, no. 7 (2024): 1420. http://dx.doi.org/10.3390/biomedicines12071420.

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Our study investigated the innate immune response to Toxoplasma gondii infection by assessing microglial phenotypic changes and sickness behavior as inflammatory response markers post-ocular tachyzoite instillation. Disease progression in Swiss albino mice was compared with the previously documented outcomes in BALB/c mice using an identical ocular route and parasite burden (2 × 105 tachyzoites), with saline as the control. Contrary to expectations, the Swiss albino mice displayed rapid, lethal disease progression, marked by pronounced sickness behaviors and mortality within 11–12 days post-in

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11

CH, Ashoka, and Mohammed S. Mustak. "Genotoxic Study of Chewing Leaf Tobacco in Swiss Albino Mice." International Journal of Life-Sciences Scientific Research 4, no. 1 (2018): 1620–26. http://dx.doi.org/10.21276/ijlssr.2018.4.1.19.

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BALKEMA, GRANT W., KATHLEEN CUSICK, and TRI-HUNG NGUYEN. "Diurnal variation in synaptic ribbon length and visual threshold." Visual Neuroscience 18, no. 5 (2001): 789–97. http://dx.doi.org/10.1017/s0952523801185123.

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Previous work suggests that photoreceptor synaptic ribbon length and absolute dark-adapted threshold may vary during a 24-h diurnal cycle. To test this hypothesis, we examined the length of photoreceptor synaptic ribbons and the dark-adapted threshold in black (+/+) and albino (c2J/c2J) C57BL/6J mice at six times over a 24-h period. Testing began 2 h after light onset (ZT 2:00) and continued at successive 4-h intervals (12 h:12 h light:dark). We determined the length of the synaptic ribbons in frozen sections by labeling them with an antibody specific for synaptic ribbons. Synaptic ribbons var

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13

Ngongeh, L.A, I.W Onyenwe, D.A Oche, G.A Musongong, and B.B. Fakae. "PREVALENCE OF CESTODE INFECTIONS IN ALBINO MICE AND RATST EASTERN: A PUBLIC HEALTH THREAT." Continental J. Animal and Veterinary Research 3, no. 2 (2011): 16–20. https://doi.org/10.5281/zenodo.818060.

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Cestode infections are known to be common in man and rodents all over the world. Cestodes of rodents (<em>Hymenolepis spp</em>) are also known to infect man. The number of mice and rats used for experimental studies are on the increase. The prevalence of cestode infections in albino mice and rats in Michael Okpara University of agriculture, Umudike and University of Nigeria, Nsukka and their environs was investigated. Faeces were collected from 350 albino mice and rats each and screened for the presence of cestode eggs by flotation and McMaster techniques. Sixty six percent and fifty percent o

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14

Donnelly, Harry, and Palle Saibaba. "Light intensity and the oestrous cycle in albino and normally pigmented mice." Laboratory Animals 27, no. 4 (1993): 385–90. http://dx.doi.org/10.1258/002367793780745598.

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The effects of light intensity (15-20 lux & 220-290 lux) on the oestrous cycle of albino and normally pigmented mice were examined. The oestrous cycle of both types of mice was shorter at the lower intensity but the difference was significant only with the black mice. The proportion of albino mice from which embryos were recovered was significantly smaller than the proportion of black mice at 15-20 lux but not at 220-290 lux. No significant differences due to strain or light intensity were found in the number of embryos recovered. We conclude that pigmented mice respond in the same way as

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15

Marcus, R. C., L. C. Wang, and C. A. Mason. "Retinal axon divergence in the optic chiasm: midline cells are unaffected by the albino mutation." Development 122, no. 3 (1996): 859–68. http://dx.doi.org/10.1242/dev.122.3.859.

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The visual pathway in albino animals is abnormal in that there is a smaller number of ipsilaterally projecting retinal ganglion cells. There are two possible sites of gene action that could result in such a defect. The first site is the retina where the amount of pigmentation in the retinal pigment epithelium is correlated with the degree of ipsilateral innervation (La Vail et al. (1978) J. Comp. Neurol. 182, 399–422). The second site is the optic chiasm, the site of retinal axon divergence. We investigated these two possibilities through a combination of in vivo and in vitro techniques. Our r

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16

ABDEL-KADER, MOHAMED R., ABDELMAWGOD A. ASRAN, AHMED A. AL-GENDY, and KAMAL E. KALEAL. "FOOD PREFERENCE FOR ALBINO RATS AND ALBINO MICE UNDER LABORATORY CONDITIONS." Egyptian Journal of Agricultural Research 92, no. 4 (2014): 1279–90. http://dx.doi.org/10.21608/ejar.2014.156762.

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SUNDAR, S. T. BINO, T. J. HARIKRISHNAN, BHASKARAN RAVI LATHA, et al. "Prevalence of syphaciosis in laboratory rodents with emphasis on species identification, treatment and Th2 cytokine response." Indian Journal of Animal Sciences 88, no. 7 (2018): 765–70. http://dx.doi.org/10.56093/ijans.v88i7.81404.

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Prevalence of syphaciosis (pinworm infection) in laboratory rats and mice, species identification, chemotherapy with ivermectin and its effect on pinworm infection, and Th2 cytokine response was studied. Using perianal tape test examination, the highest rate of pinworm infection was found in male Wistar rats (69.44%) followed by female Wistar rats (62.50%), male Balb C mice (60.60%), female Swiss Albino mice (51.42%), male Swiss Albino mice (33.33%) and female Balb C mice (32.69%). Wistar rats had maximum infection (65.97%) followed by Balb C mice (46.64%) and Swiss albino mice (42.37%). Overa

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18

Suriyakumari, K. V. P., R. Udayakumar, and T. Ruba. "HISTOLOGICAL INVESTIGATIONS ON KIDNEY OF SILDENAFIL CITRATE (EDEGRA) TREATED ALBINO MICE." International Journal of Anatomy and Research 4, no. 1 (2016): 1977–80. http://dx.doi.org/10.16965/ijar.2016.124.

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19

Qureshi, Fariha, and Mohammad Tahir. "ANTIOXIDANTS PREVENTED THE FETAL RESORPTIONSINDUCED BY SODIUM ARSENATE IN ALBINO MICE." Journal of Akhtar Saeed Medical & Dental College 01, no. 04 (2019): 135–41. https://doi.org/10.51127/jamdcv01i04oa02.

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Background andObjectives:Epidemiological studies have revealed the increased prevalenceof spontaneous abortion, stillbirth,and premature babies among women who were exposed to high levels of arsenic in consumablewater during their reproductive years. Thestudy exploredthe fetal toxicity in albino mice inoculatedby sodium arsenate and its preventionby Vitamins C& E. MaterialandMethods:Gravidalbino mice of BALB/c strain twenty-four in number were randomly distributedinto 4 groups containing6 animals in eachgroup.Control group 1was injected with distilled water 0.1ml/kg/day I/P for 18 days. A

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20

Kharat, Amol, Yogita Tarkasband, and Kiran Ramesh Kharat. "Antinociceptive, Anti-Inflammatory and Antidepressant potential of methanolic extract of Celosia argentea Linn." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 291–95. http://dx.doi.org/10.22270/jddt.v9i2-s.2700.

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The present study was done to determine the antinociceptive, anti-inflammatory and antidepressant activity of methanolic extract of leaves of Celosaia argentea (MECA) by oral administration at doses of 100, 200 and 400 mg/kg/day of body weight to healthy swiss albino mice. The MECA was studied for antinociceptive effect using Eddy’s hot plate method and tail flick method in albino mice and anti-inflammatory effect by using carrageenan-induced hind paw edema in mice and the mean increase in paw volume and % inhibition in paw volume was measured plethysmometer at different time intervals after c

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21

Balkema, Grant W., and Ursula C. Dräger. "Origins of uncrossed retinofugal projections in normal and hypopigmented mice." Visual Neuroscience 4, no. 6 (1990): 595–604. http://dx.doi.org/10.1017/s0952523800005794.

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AbstractIn albinos, the retinofugal projections to the ipsilateral side of the brain are reduced (e.g., see Guillery, 1969; LaVail et al., 1978; Lund, 1965). Although all ganglion cell types are affected, in mice the displaced ganglion cell population is the main target of the albino mutation (Dräger & Olsen, 1980). Here we tested whether this preferential effect on displaced ganglion cells is a general consequence of the melanin reduction or a pleiotropic effect unique to the albino locus, retrogradely tracing tracing retinal ganglion cells in normal C57BL/6J mice and in several non-allel

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22

Hayes, Jennifer M., and Grant W. Balkema. "Visual thresholds in mice: Comparison of retinal light damage and hypopigmentation." Visual Neuroscience 10, no. 5 (1993): 931–38. http://dx.doi.org/10.1017/s0952523800006143.

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AbstractIn previous electrophysiological experiments from hypopigmented animals (mice, rats, rabbits), single-unit recordings from both retinal ganglion axons and cells in the superior colliculus have demonstrated an increase in threshold in the dark-adapted state which is roughly proportional to the animal's ocular melanin concentration. We have examined the thresholds in hypopigmented mice by using a behavioral water maze screening test and found similar threshold elevations to the electrophysiology. In the present study, we investigated the contribution of retinal light damage to the thresh

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23

Yılmaz, Osman, Yeşim Ayırtır Başdinç, and Hüseyin Karadağ. "Comparative Investigation of Tongue and Esophagus Morphometry in Swiss Albino and Balb-c Mice." Turkish Journal of Agriculture - Food Science and Technology 12, no. 6 (2024): 999–1004. http://dx.doi.org/10.24925/turjaf.v12i6.999-1004.6787.

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This study was carried out to obtain morphometric measurement values of tongue and esophagus in Swiss Albino and Balb-c mice, to examine the biometric differences of these measurements between sexes and groups. Thirty-two mice, 16 Swiss Albino (8 males, 8 females) and 16 Balb-c (8 males, 8 females), were used for this study. Mice anesthetized with the ketamine-xylazine combination were fixed by the technique. The tongue and esophagus of the mice were carefully dissected and removed. Then, morphometric measurements of the dissected organs were taken, and statistical analysis was performed. When

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Ma, Yu’e, Lei He, Lijie Xiang, et al. "Efficiency comparison of B6(Cg)-Tyrc−2j /J and C57BL/6NTac embryos as hosts for the generation of knockout mice." Transgenic Research 30, no. 3 (2021): 275–81. http://dx.doi.org/10.1007/s11248-021-00248-9.

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AbstractCareful selection of the host embryo is critical to the efficient production of knockout (KO) mice when injecting mouse embryonic stem (mES) cells into blastocysts. B6(Cg)-Tyrc−2j/J (B6 albino) and C57BL/6NTac (B6NTac) strains of mice are widely used to produce host blastocysts for such procedures. Here, we tested these two strains to identify an appropriate match for modified agouti C57BL/6N (JM8A3.N1) mES cells. When comparing blastocyst yield, super-ovulated B6NTac mice produced more injectable blastocysts per female than B6 albino mice (8.2 vs. 5.4). There was no significant differ

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25

Gammal, Alaa. "Comparative Study on the Gross Anatomy of Some Abdominal Organs in Albino Rat (Rattus norvegicus) and Albino Mouse (Mus musculus)." Alexandria Journal of Veterinary Sciences 80, no. 1 (2024): 1. http://dx.doi.org/10.5455/ajvs.183386.

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A comparative gross anatomical study was carried out on six apparently healthy adult male albino rats (Rattus norvegicus) and albino mice (Mus musculus) (Three rats and three mice) The aim of the current work is to demonstrate the gross anatomical topography, morphology and fixation of (liver, kidney, spleen, stomach and pancreas) in order to highlight similarities and differences between both species. The animals were brought from local animal markets and delivered to the anatomy laboratory of the Faculty of Veterinary Medicine Cairo University, Egypt. After euthanasia, animals were anatomica

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S, PRAYLIN, and Bakthasingh Lazarus. Y. "INVIVO SCREENING OF THE LEAF EXTRACTS OF PITHECELLOBIUM DULCE (Roxb.)Benth● AGAINST DIABETIC SWISS ALBINOMICE." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 03 (2024): 1–13. http://dx.doi.org/10.55041/ijsrem29054.

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In India, the prevalence of diabetes mellitus is on increase and needs to be addressed appropriately. In this study area, herbal remedies are considered convenient for management of type 2 diabetes with postprandial hyperglycemia due to their traditional acceptability and availability, low costs and lesser side effects. The present study involves screening of LEAF EXTRACTS OF PITHECELLOBIUM DULCE (Roxb.) Benth for anti-diabetic activity on alloxan induced diabetic Swiss albino mice using glibenclamide as standard. Ethanol and aqueous extracts (200mg/kg b.w.) of leaves of PITHECELLOBIUM DULCE (

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Shahatha, S. S., M. O. Mousa, I. M. Ayyed, et al. "Effect of Alcoholic Extract of the Plant Conyza bonariensis on the Parasite Hymenolepis nana in Albino Mice Infected with it Experimentally." IOP Conference Series: Earth and Environmental Science 1325, no. 1 (2024): 012026. http://dx.doi.org/10.1088/1755-1315/1325/1/012026.

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Abstract This study was conducted to investigate the effect of an alcoholic extract of the Mountain grass plant Conyza bonariensis on adults of the dwarf tapeworm Hymenolepis nana in albino mice infected with it experimentally, where Albino mice of the strain Balb/C were infected with these worms experimentally, it was divided into 5 groups, each group consisting of 6 rats, where the first group (control) was given distilled water only. As for the other groups, they were dosed with different concentrations of the alcoholic extract of the plant 50, 100, and 200 mg/kg, The last group was given 1

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Gosavi, Devesh D., Amit S. Kamdi, Suvarna M. Kalambe, and Pankaj N. Bohra. "The spontaneous motor activity of aqueous extract of Withania coagulans fruits in Swiss albino mice by actophotometer." International Journal of Basic & Clinical Pharmacology 9, no. 9 (2020): 1440. http://dx.doi.org/10.18203/2319-2003.ijbcp20203633.

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Background: People spend about one third of their time in sleep every day. The various sedative and hypnotic medications used today have numerous side effects. In the late seventies a very little work was done on the Withania coagulans - a vulnerable species that is found scattered in the world. Therefore, it was essential to discover the CNS depressant activities of aqueous extract of Withania coagulans fruits in swiss albino mice by using actophotometer.Methods: The spontaneous locomotor activity was evaluated by using the actophotometer. The CNS depressant drugs decrease the locomotor activ

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T, Nageshwara Rao Bharatha Ambadasu S. Vijay Prasad A. Srinivas V. Yakaiah. "EFFECT OF NICORANDIL ON PENTYLENETETRAZOLE (PTZ) INDUCED CONVULSIONS IN MICE." International Journal of Clinical and Biomedical Research 1, no. 2 (2015): 99–101. https://doi.org/10.5281/zenodo.2532100.

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Aims & Objectives: To evaluate or screen the anticonvulsant effect of Nicorandil a potassium channel opener in Pentylenetetrazole(PTZ) induced convusions in albino mice. Materials & Methods: Mice of either sex weighing 20-25gms were selected for the present study. The animals were divided into 6 groups with each group consisting of 6 albino mice. Group 1 mice received placebo (0.2ml of distilled water) intraperitoneally (i.p), group 2 received sodium valproate 200 mg/kg/i.p. as positive control, while groups 3,4, 5 and 6 were administered Nicorandil 5, 10, 20 and 40 mg/kg i.p respectiv

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Meda, Naga Prasanna, and V. Viveka Vardhani. "Imidacloprid Induced Histopathological Alterations in the Kidneys of Male Swiss Albino Mice." Indian Journal of Applied Research 4, no. 2 (2011): 23–26. http://dx.doi.org/10.15373/2249555x/feb2014/187.

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Bhattacharya, Sanjib, and Pallab Haldar. "Trichosanthes dioica root extract induces tumor proliferation and attenuation of antioxidant system in albino mice bearing Ehrlich ascites carcinoma." Interdisciplinary Toxicology 4, no. 4 (2011): 184–90. http://dx.doi.org/10.2478/v10102-011-0028-4.

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Trichosanthes dioicaroot extract induces tumor proliferation and attenuation of antioxidant system in albino mice bearing Ehrlich ascites carcinomaTrichosanthes dioicaRoxb. (Cucurbitaceae), called pointed gourd in English, is a dioecious climber grown widely in the Indian subcontinent. The present study assessed the influence of treatment of hydroalcoholic extract ofTrichosanthes dioicaroot (TDA) on Ehrlich ascites carcinoma (EAC) in Swiss albino mice with effects on antioxidant systems. Twenty-four hours after intraperitoneal inoculation of tumor (EAC) cells in mice, TDA was administered at 2

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., Nada H. A. Al-Twaty. "Mutagenic Effects of Ethephon on Albino Mice." Journal of Biological Sciences 6, no. 6 (2006): 1041–46. http://dx.doi.org/10.3923/jbs.2006.1041.1046.

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Sharma, Suman. "Nephrotoxic Effects of Arsenic in Albino Mice." American Journal of BioScience 4, no. 3 (2016): 1. http://dx.doi.org/10.11648/j.ajbio.s.2016040301.11.

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Muralidhara and K. Narasimhamurthy. "Non-mutagenicity of capsaicin in Albino mice." Food and Chemical Toxicology 26, no. 11-12 (1988): 955–58. http://dx.doi.org/10.1016/0278-6915(88)90094-4.

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Toppozada, H., and H. Gaafar. "Experimental Inoculation ofKlebsiella rhinoscleromatisBacilli in Albino Mice." ORL 49, no. 4 (1987): 214–17. http://dx.doi.org/10.1159/000275938.

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Singh, Inder, Abhilasha Sharma, Vandana Nunia, and P. K. Goyal. "Radioprotection of Swiss albino mice byEmblica officinalis." Phytotherapy Research 19, no. 5 (2005): 444–46. http://dx.doi.org/10.1002/ptr.1600.

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Journal, Baghdad Science. "The effect of Nitrofurantoin on liver on Albino mice." Baghdad Science Journal 11, no. 2 (2014): 913–19. http://dx.doi.org/10.21123/bsj.11.2.913-919.

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the current study Included, evaluation the impact of Nitrofurantoin drug on liver in albino mice, 128 male albino mice have been used . Animals treared with (150,200 Mg/Kg) for 8 weeks . NFI caused histological changes in liver represented by , swelling of hepatocytes, disappearance of radial arrangement , vaculation of liver cells , increasing of kupffer cells and appearance of giant cells. NFT caused Congestion of blood vessels and infiltration of inflammatory cells in liver in all used concentrations.

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Chotai, Tanvi M., and Sarita M. Kapgate. "Standardization of ethanol addiction model in Swiss albino Mice." International Journal of Basic & Clinical Pharmacology 7, no. 7 (2018): 1365. http://dx.doi.org/10.18203/2319-2003.ijbcp20182683.

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Background: Addiction is compulsive need for use of a habit-forming substance. World Health Organization (WHO) reported that worldwide 3.3 million people died due to alcohol addiction in 2012-13 and 11% of the population in India indulged in heavy drinking in 2014. Addiction is a prime socio-economical problem of society. Studying alcohol dependence in humans involved many ethical issues and experimental difficulties. Hence nonhuman animal experimental model has been used for a research on the topic of alcohol intoxication and dependence. Ethanol dependence has been preferred to develop in gen

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Akhter, Rumana, Md Aminul Haque, Mohiuddin Ahmed Bhuiyan, and Mohamad Shahriar. "In vivo Pharmacological investigation of leaf of Polygonum hydropiper (L.)." Dhaka University Journal of Pharmaceutical Sciences 12, no. 2 (2014): 165–69. http://dx.doi.org/10.3329/dujps.v12i2.17619.

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The present study was planned to evaluate the anti-nociceptive, gastro intestinal motility, anti-pyretic and acute toxicity studies of leaf extract of Polygonum hydropiper leaves in albino mice following oral administration. The results showed that the anti-nociceptive activity in the scale of ethanol > n-hexane > petroleum ether > chloroform > methanol extract showed a significant result compared to diclofenac sodium. Chloroform extract showed significant results on gastro intestinal motility test. Ethanol & chloroform extracts showed considerable reduction of temperature at h

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Kumar, Ashish, Gyan Vardhan, and Ambika Sharma. "Ulcerative Dermatitis Lesions in Swiss Albino Mice: A Case Report." Advances in Research 26, no. 3 (2025): 422–25. https://doi.org/10.9734/air/2025/v26i31359.

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Aim: Ulcerative dermatitis (UD) is a common, multifactorial skin condition in laboratory mice, typically reported in C57BL/6 strains. This report documents the first known occurrence of UD in Swiss Albino mice and evaluates the response to standard topical therapy. Presentation of the Case: Four Swiss Albino mice at the Laboratory Animal Facility, AIIMS Rishikesh, presented with alopecia, pruritus, ulcerations, anorexia, and debility. Lesions appeared on the outer pinna, dorsal thorax, and caudal areas. The mice were isolated and treated with a topical cream containing Clobetasol, Neomycin, an

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Maha A. Gathwan and Zahraa H. M. Kadri. "Histological Changes in the Lung Tissues of male albino mice Exposed to Mospilan 20SG insecticide." journal of the college of basic education 22, no. 96 (2022): 121–28. http://dx.doi.org/10.35950/cbej.v22i96.9021.

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Oral administration of (20 mg/ml), of Acetamidine the active ingradiant of mospilan 20SG , the neonicotinoid insecticide that is effective against both soil and plant insects (LD50=200mg\kg), for 30 days in male albino mice aged (6-7weeks), resulted Histopathologically significant alterations in the lungs included marked. Haemorrhage and inflammatory cells infiltration and thickening in connective tissue stroma. The oral toxicity study of Acetamidine revealed that this neonicotinoid insecticide is of highly risk in albino mice.

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Sayyed, Mateen, Khan Mohib, N. Devanna, and Aziz-ur-Rahman. "Role of methanolic extract of Hemidesmus indicus in haloperidol-induced parkinsonism in albino mice-A preliminary study." International Journal of Advances in Pharmacy Medicine and Bioallied Sciences 1, no. 1 (2013): 2–6. https://doi.org/10.5281/zenodo.6982860.

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Objective: To evaluate & establish the antiparkinsonian activity of methanolic extract of Hemidesmus indicus (MEHI) against haloperidol-induced parkinsonism in Swiss albino mice. Materials & Methods: In the present study the MEHI was prepared by successive solvent extraction (Soxhlet apparatus). Two doses i.e. 75 & 100 mg/kg of MEHI were evaluated for antiparkinsonian activity in haloperidol-induced parkinsonism (catalepsy) in albino mice. Benzhexol was used as standard drug (positive control). Results: Pre-treatment of test animals with Hemidesmus indicus (75 & 100 mg/kg i.p)

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Erjon, Erjon, Yenni Sriwahyuni, Nilda Lely, and Ema Ratna Sari. "The Effect Javanese Chili Extract (Piper Retrofractum Vahl) Administration On The Increase Of Albino Male Mice Libido." FITOFARMAKA: Jurnal Ilmiah Farmasi 10, no. 2 (2020): 132–38. http://dx.doi.org/10.33751/jf.v10i2.2176.

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Libido is a sexual desire that is an important part of adult human life. The main active compound of Javanese chili is piperine. Javanese chili is reported to cause increased libido. The study aimed to evaluate the effect of administration Javanese chili extract (Piper retrofractum Vahl) to increase libido in albino male mice. The doses of Javanese chili extract used is 50 mg/kgbw; 100 mg/kgbw; and 200 mg/kg bw given as a single dose for 9 days. The parameters observed were kissing, mounting latency, and mounting frequency of albino male mice. The results showed that the administration of Java

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Balkema, Grant W., and Ursula C. Dräger. "Impaired visual thresholds in hypopigmented animals." Visual Neuroscience 6, no. 6 (1991): 577–85. http://dx.doi.org/10.1017/s095252380000256x.

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AbstractOcular hypopigmentation is associated with neurological defects in structure and function. This paper investigates the ab/Fute visual thresholds in dark-adapted hypopigmented animals compared to their normally pigmented controls. Here we asked (1) whether the threshold elevation found in hypopigmented animals is a general consequence of the reduction in melanin content; (2) if so, which melanin components in the eye are likely to influence visual thresholds; and (3) whether similar threshold defects can be detected in orders other than rodents. By single-unit recordings from the superi

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Keservani, Raj K., and Surya Prakash Gautam. "Skeletal muscle relaxant activity of different formulation of span 60 niosomes." Ars Pharmaceutica (Internet) 63, no. 1 (2021): 32–44. http://dx.doi.org/10.30827/ars.v63i1.22264.

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Introduction: Spasticity is a disease of motor neurons that manifests as accelerated muscle tone and stiffness. The niosomes can be formulated with the aid of proper adjustment of process parameters to enhance baclofen entrapment and sustaining the drug release. Method: The main purpose of this study is to compare different formulations of span 60 niosomes containing baclofen for skeletal muscle relaxant activity on mice (Swiss albino mice) by rota rod method. Results: The particle size of formulated niosomes was in the range of 3.62±0.54-4.08±0.64 µm and these were smooth, circula

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Okafor, Ugochukwu Chisom, Chijioke Christian Aniekwu, Nzube Victor Anene, and Vitus Ikechi Onyeneho. "The Pathogenicity of Aspergillus Fumigatus and Aspergillus Niger Isolated from Accumulated Poultry and Goat Droppings in Immuno-Competent Albino Mice." International Journal of Research and Scientific Innovation XI, no. XV (2024): 363–71. http://dx.doi.org/10.51244/ijrsi.2024.11150027p.

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The pathogenicity of Aspergillus fumigatus and Aspergillus niger isolated from poultry and goat droppings in immuno competent albino mice was investigated. A total of 12 soil samples of both poultry and goat droppings were collected and screened for the presence of Aspergillus fumigatus and Aspergillus niger using microbiological standard method. The pathogenicity of the isolates on immuno-competent albino mice were investigated by challenging the mice subcutaneously using 0.5 ml of the inoculum. All mice were kept under complete observation for four (4) weeks for pathological signs and sympto

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Zulfiqar, Asma, Sitwat Amna, Asma Siddique, et al. "Decrease in Body Weight and Liver Weight of Pups in Swiss Albino Mice by Spearmint Leaves Extract." Pakistan Journal of Medical and Health Sciences 16, no. 11 (2022): 290–92. http://dx.doi.org/10.53350/pjmhs20221611290.

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Objective: To evaluate the effects of spearmint leaves extract on body weight, liver weight and RTWI of pups in Swiss albino mice. Study Design: Experimental study Place and Duration of Study: Anatomy Department, Shaikh Zayed PGMI, Lahore from 1st March 2014 to 30th June 2014. Methodology: Seven male and 21 female mice were used. After conception female mice were divided into control (A), low dose (B) and high dose (C) experimental groups. There were7 mice in each group. Group A was given distilled water where as group B was given 3g/kg/day and group C were given 6g/kg/day spearmint leaves ext

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Khalid, Sumbal. "ANTIOXIDANT ROLE OF MENTHA (MINT) AGAINST CHLOROQUINE-INDUCED OXIDATIVE STRESS IN MALE ALBINO MICE." Journal of Akhtar Saeed Medical & Dental College 05, no. 04 (2023): 221–25. https://doi.org/10.51127/jamdc5i4oa04.

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Background: Many drugs, in the world, have been found to induce oxidative stress when these are given at larger doses or for longer periods. Worldwide research work is being carried out to find the antioxidant role of many herbs and plants so that these can be given prophylactically to prevent oxidative damage, done by free radicals. The objective of the study was to determine the antioxidant role of mint against chloroquine induced oxidative stress. Material and Methods: In this randomisedcontrolled study, ninety male albino mice were divided into three groups randomly. Each of the three grou

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Tabassum, Saima, Hamid Javaid Qureshi, Ambreen Anjum, Sobia Manzoor, Hafiza Hina Pasha, and Wardah Toseef. "EFFECT OF ETHANOLIC EXTRACT OF CLOVE (Eugenia Caryophyllata) ON PAIN IN MICE." Journal of Akhtar Saeed Medical & Dental College 01, no. 04 (2019): 146–50. https://doi.org/10.51127/jamdcv01i04oa04.

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Background:Pain is a natural phenomenon. There are several pharmacological medicines available in the market for pain relief. Ethanolic extract of clove is a natural ingredient and can be as beneficial as a pharmacological drug for pain relief.Objective:To determine the effectof Eugenia caryophyllata flower buds ethanolic extract on experimentally induced pain in albino mice.Material and Methods: This randomized trial was done on 90male albino mice. An intraperitoneal injection of 0.6% acetic acidwasinduced for the writhing test as a chemical model of nociception. Mice were divided randomly in

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Krishna, Kant Nirala, and Kumar Singh Rohit. "Effect of Aqueous Extract of Terminalia Bellirica Fruit Pulp: An Animal Experimental Study." International Journal of Pharmaceutical and Clinical Research 14, no. 1 (2022): 219–22. https://doi.org/10.5281/zenodo.13863515.

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<strong>Aim:</strong> Effect of aqueous Extract of Terminalia bellirica fruit pulp on Alcohol affected learning in swiss albino mice. <strong>Methods: </strong>This study was conducted in the Department of Pharmacology, ANMMCH Gaya, Bihar, India for 1 year. 64 Swiss albino mice of either sex weighing 20-30 grams bred and maintained under standard conditions in the central animal house in AJIMS and RC were used. The standard drug Piracetam was obtained from micro labs. The dried fruit of Terminalia bellirica was obtained by Ayurvedic Dispensary, BIHAR. Aqueous Extract of Terminal

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