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1

V, Manoj Narayan, Murugan M, Prerna Jane J, and s. stevenson. "Assessing Allergen Sensitization Patterns in Allergic Rhinitis Patients." Journal of Chemical Health Risks 13, no. 6 (2023): 306–9. https://doi.org/10.52783/jchr.v13.i6.1571.

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https://jchr.org/index.php/JCHR/article/view/1571 This research aims to provide insights into the diverse allergenic triggers that contribute to the development and exacerbation of allergic rhinitis, shedding light on the significance of personalized approaches to diagnosis and management. The study begins by delving into the epidemiology of allergic rhinitis, highlighting its increasing prevalence worldwide and the associated healthcare burden. Subsequently, it elucidates the various allergens that are commonly implicated in the development of allergic rhinitis, encompassing both indoor and o
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Lei, Dawn K., and Carol Saltoun. "Allergen immunotherapy: definition, indications, and reactions." Allergy and Asthma Proceedings 40, no. 6 (2019): 369–71. http://dx.doi.org/10.2500/aap.2019.40.4249.

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Specific allergen immunotherapy is the administration of increasing amounts of specific allergens to which the patient has type I immediate hypersensitivity. It is a disease-modifying therapy, indicated for the treatment of allergic rhinitis, allergic conjunctivitis, allergic asthma, and Hymenoptera hypersensitivity. Specific immunoglobulin E (IgE) antibodies for appropriate allergens for immunotherapy must be documented. Indications for allergen immunotherapy include (1) inadequate symptom control despite pharmacotherapy and avoidance measures; (2) a desire to reduce the morbidity from allerg
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Oshikata, Chiyako, Maiko Watanabe, Kazuhiro Hashimoto, et al. "Mite allergen avoidance decreases allergic symptoms in children in Ishinomaki city of Japan after natural disasters." Allergologia et Immunopathologia 50, no. 2 (2022): 23–32. http://dx.doi.org/10.15586/aei.v50i2.483.

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Objective: We investigated the prevalence of asthma, rhinitis, and atopic dermatitis in children, evaluated the mite allergen levels in their bedding after the Great East Japan Earthquake, and assessed changes in allergic symptoms in children and their families after allergen avoidance practices. Methods: We performed a survey for the International Study of Asthma and Allergies in Childhood (ISAAC) comprising 1109 children, aged 7–8 years, living in Ishinomaki, Japan. We collected responses from 464 children, and in 2016, measured the level of Dermatophagoides group 1 (Der 1) in the bedding of
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Parikhal, Lauren, Hillary Abraham, Alea Mehler, et al. "These Labels are Nuts: Challenges to Safe Product Identification for Nut-Allergic Consumers." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 62, no. 1 (2018): 987–91. http://dx.doi.org/10.1177/1541931218621228.

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Allergen information on food labels is not standardized, making allergen avoidance difficult for consumers. This study investigated the speed and accuracy of allergen identification on commercial packaging across different types of warning labels. The results identified packaging label characteristics significantly correlated with faster and more accurate identification of allergens. Standardizing warning and safe-to-consume labels may reduce risk of accidental allergen exposure for consumers managing food allergies.
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Gowda, G., S. Lakshmi, B. G. Parasuramalu, C. Nagaraj, B. V. C. Gowda, and K. G. Somashekara. "A study on allergen sensitivity in patients with allergic rhinitis in Bangalore, India." Journal of Laryngology & Otology 128, no. 10 (2014): 892–96. http://dx.doi.org/10.1017/s0022215114001984.

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AbstractBackground:Allergic rhinitis is the most common form of non-infectious rhinitis, affecting 500 million people worldwide, with one-fifth of those affected living in the Indian subcontinent. The skin prick test is the most valuable test for detecting offending allergens, and can be helpful for patient education, allergen avoidance and immunotherapy planning.Method:The skin prick test was performed with 49 allergens in 486 patients who presented with symptoms of allergic rhinitis, and the allergen profile was studied.Results:Of the 486 allergic rhinitis patients, 335 (68.93 per cent) show
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Volpicella, Mariateresa, Claudia Leoni, Maria C. G. Dileo, and Luigi R. Ceci. "Progress in the Analysis of Food Allergens through Molecular Biology Approaches." Cells 8, no. 9 (2019): 1073. http://dx.doi.org/10.3390/cells8091073.

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Food allergies associated with class E immunoglobulins (IgE) are a serious health problem that affects between 1% and 10% of the population of developing countries, with a variability that depends on the geographical area and age range considered. These allergies are caused by a cross-link reaction between a specific food protein (the allergen) and the host IgE. Allergic reactions can range from mild itching to anaphylactic shock and there are no clues to predict the effects of an allergen. Strict avoidance of allergenic food is the only way to avoid possible serious allergic reactions. In the
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Gupta, Ruchi S., Steve L. Taylor, Joseph L. Baumert, Lauren M. Kao, Erik Schuster, and Bridget M. Smith. "Economic Factors Impacting Food Allergen Management: Perspectives from the Food Industry." Journal of Food Protection 80, no. 10 (2017): 1719–25. http://dx.doi.org/10.4315/0362-028x.jfp-17-060.

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ABSTRACT Food allergies affect up to 8% of children in the United States and may occasionally lead to severe life-threatening reactions. Because there is currently no cure for food allergies, strict avoidance of the allergen-containing foods is the only means of preventing an allergic reaction. Consumers rely on food manufacturers to reliably track and declare the presence of food allergens in products. Over the past 10 to 20 years, the food industry has increasingly adopted allergen control approaches in its processing facilities. However, the major industry costs related to food allergen man
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Heine, Ralf G. "Dietary strategies for early immune modulation in primary food allergy prevention." BMJ Nutrition, Prevention & Health 6, Suppl 3 (2023): s8—s19. http://dx.doi.org/10.1136/bmjnph-2023-000678.

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As the global incidence of food allergies continues to rise, effective primary prevention strategies remain a public health priority. Eczema in early infancy is a major risk factor for IgE-mediated food allergies. Exposure to food allergens via inflamed skin promotes a cascade of allergic immune responses and increases the risk of IgE-mediated food allergies. By contrast, early exposure to food allergens via the gut is likely to induce oral tolerance. Landmark studies have demonstrated a significant reduction in the incidence of egg and peanut allergy in response to the early dietary introduct
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Toader, Stefan Vasile, Oana Mihaela Condurache Hritcu, Cristina Popa, Ana Maria Sciuca, George Maftei, and Mihaela Paula Toader. "HYPERSENSITIVITY REACTIONS AFFECTING ORAL MUCOSA: DIAGNOSTIC AND THERAPEUTIC CHALLENGES." Romanian Journal of Oral Rehabilitation 16, no. 3 (2024): 163–71. https://doi.org/10.62610/rjor.2024.3.16.17.

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Hypersensitivity reactions affecting the oral mucosa present a significant clinical challenge due to their diverse manifestations and the wide range of potential allergens involved. This article explores the types of allergic reactions commonly observed in the oral cavity, including contact allergies and systemic allergic reactions, emphasising their clinical presentations and diagnostic approaches. Common allergens such as metals and resin-based dental materials are highlighted, discussing their impact on oral health. Diagnostic strategies, including clinical examination, history taking, cuta
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Sakshi, Sakshi, Rupa Mazumder, Monika Monika, Neha Singh, and Bimlesh Kumar. "Novel approaches for allergen-specific immunotherapy—An overview." Trends in Immunotherapy 7, no. 1 (2023): 2026. http://dx.doi.org/10.24294/ti.v7.i1.2026.

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Allergen-specific immunotherapy (AIT) is an allergen-specific treatment for people with IgE-related allergies. Allergen-specific immunotherapy (AIT) is used to treat allergic disorders when symptoms persist despite medication and allergen avoidance. The therapy is presumed effective if it reduces the use of medications, improves the quality of life even after discontinuation of treatment, as well as prevents the conversion of one type of allergy to the other and the development of new sensitization. The allergen-specific immunotherapeutic agents can be administered sublingually, subcutaneously
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Cunico, Daniela, Giuliana Giannì, Sara Scavone, Enrico Vito Buono, and Carlo Caffarelli. "The Relationship Between Asthma and Food Allergies in Children." Children 11, no. 11 (2024): 1295. http://dx.doi.org/10.3390/children11111295.

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Asthma and food allergy are two complex allergic diseases with an increasing prevalence in childhood. They share risk factors, including atopic family history, atopic dermatitis, allergen sensitization, and T2 inflammatory pathways. Several studies have shown that in children with a food allergy, the risk of developing asthma, particularly in early childhood, is high. Food allergen intake or the inhalation of aerosolized allergens can induce respiratory symptoms such as bronchospasm. Patients with both conditions have an increased risk of severe asthma exacerbations, hospitalization, and morta
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Tovey, Euan. "Allergen avoidance." Mediators of Inflammation 10, no. 6 (2001): 298–301. http://dx.doi.org/10.1080/09629350152700957.

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Platts-Mills, Thomas A. E. "Allergen avoidance." Journal of Allergy and Clinical Immunology 113, no. 3 (2004): 388–91. http://dx.doi.org/10.1016/j.jaci.2003.12.027.

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Tovey, Euan R. "Allergen avoidance." Current Allergy and Asthma Reports 8, no. 2 (2008): 126–32. http://dx.doi.org/10.1007/s11882-008-0022-x.

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de Leon, Maria P., Jennifer M. Rolland, and Robyn E. O'Hehir. "The peanut allergy epidemic: allergen molecular characterisation and prospects for specific therapy." Expert Reviews in Molecular Medicine 9, no. 1 (2007): 1–18. http://dx.doi.org/10.1017/s1462399407000208.

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AbstractPeanut (Arachis hypogaea) allergy is a major cause of food-induced anaphylaxis, with increasing prevalence worldwide. To date, there is no cure for peanut allergy, and, unlike many other food allergies, it usually persists through to adulthood. Prevention of exposure to peanuts is managed through strict avoidance, which can be compromised by the frequent use of peanuts and peanut products in food preparations. Conventional subcutaneous-injection allergen immunotherapy using crude peanut extract is not a recommended treatment because of the risk of severe side effects, largely as a resu
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Schmitt, David A., Hsiaopo Cheng, Soheila J. Maleki, and A. Wesley Burks. "Competitive Inhibition ELISA for Quantification of Ara h 1 and Ara h 2, the Major Allergens of Peanuts." Journal of AOAC INTERNATIONAL 87, no. 6 (2004): 1492–97. http://dx.doi.org/10.1093/jaoac/87.6.1492.

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Abstract Allergies to peanuts are becoming an increasingly important health problem as a result of the persistence and severity of the reaction in allergic individuals. Because no treatment currently is available, avoidance is the only option for peanut-allergic individuals. Avoidance of an abundant and often disguised food such as peanuts, however, is very difficult; therefore, competitive inhibition ELISAs were developed to detect and quantitate each of the major peanut allergens, Ara h 1 and Ara h 2. Under optimal conditions for each assay, the sensitivity of the Ara h 1 and Ara h 2 detecti
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Tomé, Miguel, and Olga Lourenço. "Avoidance Measures for Patients with Allergic Rhinitis: A Scoping Review." Children 10, no. 2 (2023): 300. http://dx.doi.org/10.3390/children10020300.

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Environmental allergen control is recommended as an essential part of allergic rhinitis (AR) management guidelines. In this scoping review, our objective is to identify measures of allergen avoidance and to evaluate their effectiveness in the management of AR. We conducted systematic searches for randomized controlled trials and observational studies in PubMed, the Cochrane Central Register of Controlled Trials, and the Web of Science databases. We included all types of control measures based on allergen eviction or reduction in exposure. Overall, 18 studies satisfied our criteria and were thu
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Marinovic, María Angélica. "ENVIRONMENTAL ALLERGENS AND ASTHMA." Neumología Pediátrica 18, no. 4 (2023): 108–11. http://dx.doi.org/10.51451/1zqrvz35.

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Exposure to inhalant allergens is associated with allergen-specific sensitization, a risk factor for the development of bronchial asthma, along with genetic and environmental factors. Early life exposure to mites increases the risk of sensitization and development of asthma in high-risk children. The same would occur with cat allergen levels inside the house and increased risk of sensitization in preschool and school. On the other hand, early contact with multiple microorganisms contributes to preventive immunomodulation by inducing tolerance to allergens. Climate change has been shown to incr
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Durham, S. R. "Allergen avoidance measures." Respiratory Medicine 90, no. 8 (1996): 441–45. http://dx.doi.org/10.1016/s0954-6111(96)90168-7.

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Takaoka, Yuri, Akihiro Maeta, Atsuko Nakano, et al. "Pediatric allergies in Japan: Coronavirus disease pandemic-related risk factors." Asia Pacific Allergy 13, no. 3 (2023): 114–20. http://dx.doi.org/10.5415/apallergy.0000000000000116.

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Background: The coronavirus disease 2019 (COVID-19) pandemic impacted various parts of society, including Japanese children with allergies. Objective: This study investigated risk factors for pediatric allergic diseases associated with the state of emergency owing to the COVID-19 pandemic in Japan, including during school closures. Methods: Parents of pediatric patients (0–15 years) with allergies were enrolled and queried regarding the impact of school closure on pediatric allergies compared to that before the COVID-19 pandemic. Results: A valid response was obtained from 2302 parents; 1740 o
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Nakamatsu, Bernardo Yassunobu, Archangelo Padreca Fernandes, Débora da Silva, Ludimila Souza Santos, Thamires Rodrigues de Sousa, and Jefferson Russo Victor. "Suitable Interpretation of Skin Prick Test and Biomedical Guidance Leads to a Better Clinical State in Atopic Individuals with High Indoor Permanence: Possible Therapeutic Implications." Biologics 1, no. 2 (2021): 222–30. http://dx.doi.org/10.3390/biologics1020014.

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Indoor conditions contribute to allergen sensitization and multiple allergens reactivity, mainly for inhaled allergens. This study analyzes if Skin Prick Test (SPT) combined with efficient individual biomedical guidance about allergy development’s social, biological, and environmental aspects can yield a better clinical state with therapeutic implications for atopic individuals with high indoor permanence. We recruited atopic and non-atopic volunteers (clinically and in vitro diagnosed) with indoor permanence above 15 h per day and without previous SPT evaluation. The SPT and serum anti-allerg
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Tomei, Leonardo, Antonella Muraro, Mattia Giovannini, et al. "Hidden and Rare Food Allergens in Pediatric Age." Nutrients 15, no. 6 (2023): 1386. http://dx.doi.org/10.3390/nu15061386.

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In food allergy management, the avoidance of the allergen that caused the reaction plays a fundamental role. Nevertheless, that can be thwarted in case of accidental exposure to a rare or hidden allergen, causing the adoption of a monotonous diet and a consequent reduction in the quality of life of the patient and their family. The identification of a rare and hidden allergen is an important diagnostic challenge, taking into account that a significant proportion of all food reactions is in reality due to them. The aim of the present review is to provide the pediatric allergist an overview of t
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Dhaliwal, Amandeep Kaur. "Role of Abiotic Factors on House Dust Mite Population: Control and Allergen Avoidance - A Review Article." Journal of Scientific Research 66, no. 04 (2022): 58–67. http://dx.doi.org/10.37398/jsr.2022.660409.

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House dust mites (HDM’s) are an important source of indoor allergens in the house dust and cause various kinds of allergies. They are strongly influenced by abiotic factors such as temperature, relative humidity and seasonal variations. HDM’s are present in houses all over the year but their number varies in different seasons and habitats. The moderate environmental temperature, high relative humidity and adequate food sources are the key factors for their proliferation. The season has a great effect on the mite population. In the rainy season, moderate temperature and high relative humidity a
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Papapostolou, Niki, and Michael Makris. "Allergic Asthma in the Era of Personalized Medicine." Journal of Personalized Medicine 12, no. 7 (2022): 1162. http://dx.doi.org/10.3390/jpm12071162.

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Allergic asthma is the most common asthma phenotype and is characterized by IgE sensitization to airborne allergens and subsequent typical asthmatic symptoms after exposure. A form of type 2 (T2) airway inflammation underlies allergic asthma. It usually arises in childhood and is accompanied by multimorbidity presenting with the occurrence of other atopic diseases, such as atopic dermatitis and allergic rhinitis. Diagnosis of the allergic endotype is based on in vivo (skin prick tests) and/or in vitro (allergen-specific IgE levels, component-resolved diagnosis (CRD)) documentation of allergic
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Bustamante Hernandez, Leslie. "Food allergies as a promoter of transient anxiety-like behavior." Journal of Immunology 212, no. 1_Supplement (2024): 0621_4164. http://dx.doi.org/10.4049/jimmunol.212.supp.0621.4164.

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Abstract Food allergies impact human health, including mood. Allergen challenges in mice promote central amygdala activation, the integrative hub for anxiety and other mood disorders. Indeed, food allergic individuals show higher prevalence of anxiety. We hypothesize that food allergies induce anxiety. Female BALB/c mice received OVA/alum sensitization (or PBS/alum for control) subcutaneously on days 0 and 7, followed by five OVA oral challenges every three days from days 14 to 28. Behaviors were assessed using standard anxiety tests (open field test, OFT, elevated plus maze, EPM). Development
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Mirmakhmudovna, Mirkhamidova Sevara, Jenifer Alat Stephen, Karimbayev Shakhrambay Dexkanbayevich, and Abdurashitova Sharafat Abdumajidovna. "IMPLEMENTATION AND RESULTS OF SURVEY HELD IN THE AWARENESS OF PUBLIC ON ALLERGIC CONTACT DERMATITIS." International Journal of Medical Sciences And Clinical Research 03, no. 03 (2023): 78–86. http://dx.doi.org/10.37547/ijmscr/volume03issue03-11.

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Allergic Contact Dermatitis due to cosmetic products is a common dermatologic complaint that considerably affects the quality of life. Most cases are caused by skin hygiene and moisturizing products followed by cosmetic hair and nail products. Fragrances are the most cause of allergy to cosmetics, followed by hair dyes and preservative [1]. Patch Testing remains the gold standard for identification of causative allergens [5]. Careful determination of allergen avoidance can result in dramatic clinical improvement.
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Lariou, Maria Stella, Stavroula Dikalioti, Nick Dessypris, et al. "Country specific serum IgE reactivity profile and concordance with allergic history among acute lymphoblastic leukemia children and controls." Journal of Clinical Oncology 30, no. 15_suppl (2012): e20002-e20002. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e20002.

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e20002 Background: Allergy has been studied as a risk factor for several malignancies, including childhood leukemia; yet, the tentative etiological nature of this association needs to be further explored. Published studies suffer inappropriate study design and accuracy of exposure variables. In response to the latter need, this study aims to use country specific biological markers, namely levels of the most prevalent allergen-specific immunoglobulin E (IgE) antibodies in Greece as an alternative exposure measurement to history of allergy and compare their concordance with allergic history. Met
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Lee, Mey-Fann, Chu-Hui Chiang, Shyh-Jye Lin, Chi-Sheng Wu, and Yi-Hsing Chen. "Effectiveness and safety of oral lactococci-based vaccine encoding triple common allergens to prevent airway allergy in mice." PLOS ONE 16, no. 12 (2021): e0261333. http://dx.doi.org/10.1371/journal.pone.0261333.

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Allergic airway disease is the most common chronic airway inflammatory disorder in developed countries. House dust mite, cockroach, and mold are the leading allergens in most tropical and subtropical countries, including Taiwan. As allergen avoidance is difficult for patients allergic to these perennial indoor allergens, allergen-specific immunotherapy (ASIT) is the only available allergen-specific and disease-modifying treatment. However, for patients sensitized to multiple allergens, ASIT using each corresponding allergen is cumbersome. In the present study, we developed a recombinant L. lac
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Gore, R. B., and A. Custovic. "Is allergen avoidance effective?*." Clinical & Experimental Allergy 32, no. 5 (2002): 662–66. http://dx.doi.org/10.1046/j.1365-2222.2002.01366.x.

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Fawcett IV, William A. "ALLERGEN IMMUNOTHERAPY AND AVOIDANCE." Primary Care: Clinics in Office Practice 25, no. 4 (1998): 869–83. http://dx.doi.org/10.1016/s0095-4543(05)70093-2.

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Bush, Robert K. "Does Allergen Avoidance Work?" Immunology and Allergy Clinics of North America 31, no. 3 (2011): 493–507. http://dx.doi.org/10.1016/j.iac.2011.05.005.

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Upton, Julia E. M. "Efficacy, effectiveness and other patient-centered outcomes of oral immunotherapy." Journal of Food Allergy 4, no. 2 (2022): 28–33. http://dx.doi.org/10.2500/jfa.2022.4.220017.

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Oral immunotherapy (OIT) is the medically supervised ingestion of a food allergen. Understanding of the expected outcomes of OIT allow for risk-benefit assessments for patient-centered decisions. The efficacy of OIT to achieve desensitization in children has been confirmed in multiple meta-analyses, even with vastly disparate study populations and methodologies. Most children initiated on OIT will achieve the ability to eat more allergen before experiencing an allergic reaction than if they continue to avoid their allergen. This effect is diminished without regular ingestion. Previous meta-ana
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Mahler, Vera. "Präventionskonzepte für Nahrungsmittelallergien im Wandel." Kompass Dermatologie 7, no. 3 (2019): 123–25. http://dx.doi.org/10.1159/000501010.

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In view of the dramatic rise in the prevalence of food allergy globally, effective prevention strategies have become a public health priority. Several models have emerged around the etiology of food allergy, including the hygiene hypothesis, dual allergen exposure hypothesis, and vitamin D hypothesis. These form the basis for current and potential prevention strategies. Breastfeeding remains a key pillar of primary allergy prevention. Other nutritional interventions, including the use of whey-based, partially hydrolyzed formula in non-breastfed infants, also play an important role. In recent y
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Heine, Ralf G. "Food Allergy Prevention and Treatment by Targeted Nutrition." Annals of Nutrition and Metabolism 72, Suppl. 3 (2018): 33–45. http://dx.doi.org/10.1159/000487380.

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In view of the dramatic rise in the prevalence of food allergy globally, effective prevention strategies have become a public health priority. Several models have emerged around the etiology of food allergy, including the hygiene hypothesis, dual allergen exposure hypothesis, and vitamin D hypothesis. These form the basis for current and potential prevention strategies. Breastfeeding remains a key pillar of primary allergy prevention. Other nutritional interventions, including the use of whey-based, partially hydrolyzed formula in non-breastfed infants, also play an important role. In recent y
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Paris, Juan L., Paz de la Torre, and Ana I. Flores. "New Therapeutic Approaches for Allergy: A Review of Cell Therapy and Bio- or Nano-Material-Based Strategies." Pharmaceutics 13, no. 12 (2021): 2149. http://dx.doi.org/10.3390/pharmaceutics13122149.

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Allergy constitutes a major health issue due to its large prevalence. The established therapeutic approaches (allergen avoidance, antihistamines, and corticosteroids) do not address the underlying causes of the pathology, highlighting the need for other long-term treatment options. Antigen-specific immunotherapy enables the long-term control of allergic diseases by promoting immunological tolerance to the allergen. However, efficacious immunotherapies are not available for all possible allergens, and the risk of undesired reactions during therapy remains a concern, especially in patients with
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Farooque, Sophie. "Diagnosis, allergen avoidance and treatment of allergic rhinitis." Prescriber 20, no. 10 (2009): 38–48. http://dx.doi.org/10.1002/psb.516.

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Terada, Tetsuya, and Ryo Kawata. "Early Intervention is Important to Prevent Sensitization to New Allergens." Medical Sciences 6, no. 4 (2018): 114. http://dx.doi.org/10.3390/medsci6040114.

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We review current management for allergic rhinitis and possible new treatments for this condition. Management of allergic rhinitis includes promotion of protective factors, avoidance of allergens, and possibly immunotherapy. In recent years, the incidence of allergic rhinitis has increased in many countries. Early intervention at different stages is an important part of management. Allergic disease in infants has been described as the allergic march, commencing with atopic dermatitis accompanied by infantile asthma and progressing to perennial allergic rhinitis induced by house dust mite aller
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Lin, Shang-Hung, and Yin-Cheng Chao. "Clinical Characteristics and Patch Test Results in 57 Patients with Contact Dermatitis in Southern Taiwan." Journal of Clinical Medicine 14, no. 7 (2025): 2291. https://doi.org/10.3390/jcm14072291.

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Background/Objectives: Patch testing is a valuable clinical tool for identifying the causes of allergic contact dermatitis (ACD). This study aimed to identify common allergens in southern Taiwan. Methods: A retrospective review of patch test data from April 2019 to August 2023 was conducted at a tertiary medical center. The European Baseline Series of allergens was utilized to evaluate and identify the causes of dermatitis. The prevalence rates of contact sensitization to each allergen were calculated. Results: A total of 57 patients (mean age 41.8 years) with contact dermatitis who underwent
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Warner, John O. "Use of temperature-controlled laminar airflow in the management of atopic asthma: clinical evidence and experience." Therapeutic Advances in Respiratory Disease 11, no. 4 (2017): 181–88. http://dx.doi.org/10.1177/1753465817690505.

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Avoidance of allergens in the treatment of asthma has hitherto not achieved significant benefit despite the strong evidence that allergy both increases severity and contributes to exacerbations of asthma. House dust mite, cat and dog allergens are the most common perennial allergic triggers and most avoidance strategies have focused on reducing exposures in bedrooms. Cochrane reviews have suggested that they neither significantly reduce allergen levels nor improve asthma. While the lack of efficacy may be assumed to be a consequence of exposures occurring outside the bedroom, prolonged sleep i
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Chandra b c, Smitha, Rashmi Ramashesh, and Mohan G. "Study to Assess the Efficacy of Different Concentration of Nasal Douching on Symptoms and Mucociliary Clearance in Persistent Allergic Rhinitis." Bengal Journal of Otolaryngology and Head Neck Surgery 30, no. 2 (2023): 156–61. http://dx.doi.org/10.47210/bjohns.2022.v30i2.680.

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Introduction: Allergic rhinitis (AR) is acknowledged as a significant health challenge on a global scale affecting 08 – 39.7% of total population. The management of Allergic rhinitis encompasses patient education on avoidance of allergens as well as the use of pharmacotherapy and allergen- specific immunotherapy. Avoidance of allergen may not be practically applicable always and the pharmacological treatment has side effects on long term use. Hence an alternate treatment modality is required to alleviate the symptom for long duration with less side effects. Materials and Methods: we conducted
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Terada, Tetsuya, and Ryo Kawata. "Diagnosis and Treatment of Local Allergic Rhinitis." Pathogens 11, no. 1 (2022): 80. http://dx.doi.org/10.3390/pathogens11010080.

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Some patients with chronic rhinitis have a positive nasal allergen provocation test (NAPT) without systemic IgE sensitization by skin prick tests or serum allergen-specific IgE (sIgE). This novel concept is called local allergic rhinitis (LAR) and affects children and adults worldwide, but is underdiagnosed. LAR is not just the initial state of allergic rhinitis (AR), it is a unique form of chronic rhinitis that is neither classical AR nor non-AR. Many of the features of AR and LAR are similar, such as a positive NAPT, positive type 2 inflammatory markers, including the nasal discharge of sIgE
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Abdelwahab, Heba W., Amina A. El-Maksoud, Mahmoud M. Elhosiny, and Dina A. Abdalla. "Allergen sensitization patterns concerning different governorates in Egypt: a retrospective study." Egyptian Journal of Chest Diseases and Tuberculosis 73, no. 4 (2024): 377–81. http://dx.doi.org/10.4103/ecdt.ecdt_25_24.

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Background Allergic disorders afflict 22% of the world’s population. Treatment and prevention of allergic diseases are dependent on correctly identifying the causal allergens and implementing appropriate avoidance approaches. We aimed to assess the variation in patterns of allergen sensitization among patients with allergic disorders in different Egyptian governorates. Methods This retrospective study included patients with allergic disorders attending an allergen immunotherapy outpatient clinic. Demographic data, diagnosis of allergic disorders, and skin prick test results of enrolled patient
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Putra Rio, Yugo Berri, and Dwitya Elvira. "The Role of Immunotherapy in the Management of Food Allergy." International Journal of Research and Review 11, no. 12 (2024): 14–24. https://doi.org/10.52403/ijrr.20241203.

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Food allergy is a health disorder that results from a specific immune response to food. According to the World Allergy Organisation (WAO), 22% of the world's population suffers from allergies, and this number is increasing every year. The increasing morbidity and mortality rates of food allergy cases highlight the need for accurate diagnosis and appropriate treatment. Advances in science and technology have enabled a paradigm shift in allergy prevention, moving from allergen avoidance to desensitisation and active induction of immunological tolerance (immunotherapy). Immunotherapy for food all
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Sachs, Martin I. "INDOOR ALLERGEN LEVELS IN DAY NURSERIES." Pediatrics 98, no. 2 (1996): 319. http://dx.doi.org/10.1542/peds.98.2.319.

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The level of indoor allergens were lower in day nurseries than in most houses. Most samples contain allergen levels below threshold levels for sensitization. The risk of sensitization to indoor allergens in day nurseries for infants appears to be less than in their own homes. It also appears that the efficacy of avoidance measures such as the use of synthetic protective mattress covers and frequent washing of sheets and toys is effective.
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Lieberman, Jay Adam. "Identifying thresholds of reaction for different foods." Journal of Food Allergy 6, no. 1 (2024): 21–25. http://dx.doi.org/10.2500/jfa.2024.6.240006.

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Current food allergy management universally treats all patients with food allergy as being at risk for anaphylaxis (with the exception perhaps of pollen food allergy syndrome). Thus, patients are told to avoid the allergenic food in all potentially allergic forms and amounts. However, research over the past 2 decades has shown that many patients will tolerate small amounts of the allergen without any allergic reaction. Thus, if one were able to identify the threshold of reactivity, this could change management. At the population level, establishing levels at which the vast majority of patients
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Sun, Wai Y., and Claudine S. Bonder. "Sphingolipids: A Potential Molecular Approach to Treat Allergic Inflammation." Journal of Allergy 2012 (December 18, 2012): 1–14. http://dx.doi.org/10.1155/2012/154174.

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Allergic inflammation is an immune response to foreign antigens, which begins within minutes of exposure to the allergen followed by a late phase leading to chronic inflammation. Prolonged allergic inflammation manifests in diseases such as urticaria and rhino-conjunctivitis, as well as chronic asthma and life-threatening anaphylaxis. The prevalence of allergic diseases is profound with 25% of the worldwide population affected and a rising trend across all ages, gender, and racial groups. The identification and avoidance of allergens can manage this disease, but this is not always possible wit
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Cebolla-Verdugo, Marta, Juan Pablo Velasco-Amador, and Francisco José Navarro-Triviño. "Contact Dermatitis Due to Hair Care Products: A Comprehensive Review." Cosmetics 11, no. 3 (2024): 78. http://dx.doi.org/10.3390/cosmetics11030078.

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Hair cosmetics are in fashion. Numerous products are commonly used in combination. Frequent allergens are present in hair cosmetics, which, with almost daily use, increase the risk of sensitization. Familiarity with the clinical distribution of the eczematous rash is necessary to seriously consider patch testing. Not all the products on the market are haptens. It is necessary to know how to patch your own products. When avoidance of the allergen is not possible, new treatments are evaluated to combat allergic contact dermatitis, mainly of the occupational type. In this manuscript, a complete a
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van Eeden, Megan E., Aida I. Vientós-Plotts, Leah A. Cohn, and Carol R. Reinero. "Serum allergen-specific IgE reactivity: is there an association with clinical severity and airway eosinophilia in asthmatic cats?" Journal of Feline Medicine and Surgery 22, no. 12 (2020): 1129–36. http://dx.doi.org/10.1177/1098612x20907178.

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Objectives The aim of this study was to evaluate the results of serum allergen-specific IgE testing in cats with a clinical diagnosis of asthma and to determine if the number of allergens with positive IgE reactivity and magnitude of positive IgE responses would be associated with the severity of clinical signs or airway eosinophilia. Methods Medical records from 2008 to 2018 were retrospectively reviewed. Inclusion required a diagnosis of feline asthma based on consistent clinicopathologic features and bronchoalveolar lavage (BAL) cytology with >10% eosinophils; additionally, cats needed t
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Lester, M. "Allergen Avoidance "Mite" Be Preventive." AAP Grand Rounds 9, no. 2 (2003): 22–23. http://dx.doi.org/10.1542/gr.9-2-22.

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Howarth, Peter H. "ALLERGEN AVOIDANCE AND CLINICAL PRACTICE." Clinical Experimental Allergy 23, s1 (1993): 7. http://dx.doi.org/10.1111/j.1365-2222.1993.tb02923.x.

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