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Rozprawy doktorskie na temat „Allergic response”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 5 lutego 2022

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1

Buske-Kirschbaum, Angelika. "Cortisol Responses to Stress in Allergic Children: Interaction with the Immune Response." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-135731.

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Allergic manifestations are increasingly common in infants and children. Accumulating evidence suggests that the ‘epidemic’ increase of childhood allergy may be associated with environmental factors such as stress. Although the impact of stress on the manifestation and exacerbation of allergy has been demonstrated, the underlying mechanisms of stress-induced exacerbation are still obscure. A growing number of studies have suggested an altered hypothalamus-pituitary-adrenal (HPA) axis function to stress in allergic children. It is speculated that a dysfunctional HPA axis in response to stress m

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Buske-Kirschbaum, Angelika. "Cortisol Responses to Stress in Allergic Children: Interaction with the Immune Response." Karger, 2009. https://tud.qucosa.de/id/qucosa%3A27671.

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Allergic manifestations are increasingly common in infants and children. Accumulating evidence suggests that the ‘epidemic’ increase of childhood allergy may be associated with environmental factors such as stress. Although the impact of stress on the manifestation and exacerbation of allergy has been demonstrated, the underlying mechanisms of stress-induced exacerbation are still obscure. A growing number of studies have suggested an altered hypothalamus-pituitary-adrenal (HPA) axis function to stress in allergic children. It is speculated that a dysfunctional HPA axis in response to stress m

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3

Cameron, Elizabeth Anne. "Local isotype switching to IgE within allergic nasal mucosa in response to allergen exposure." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0035/NQ64528.pdf.

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4

Al, Hamdani A. "The measurement of muscle strength in allergic response." Thesis, University of Salford, 1990. http://usir.salford.ac.uk/14798/.

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The purpose of this thesis was to show a relationship between muscle strength and allergic reactions. Clinics have for many years relied on what have become traditional methods for testing for allergic reactions. These include such tests as the Patch test and the Skin-Prick test. Both these tests cause discomfort and irritation to sensitive patients. The historical development of allergies is outlined, showing that scientists and clinicians in the late 18th and early 19th century were aware of certain reactions which people showed to apparently normal non-reactive foods. The development of met

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5

Spada, Clayton Samuel. "Mediators of acute inflammation and their roles in modulating in vivo leukocyte infiltration and pathobiologic activity in the conjunctiva." Thesis, De Montfort University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278549.

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Elms, Joanne. "The immune functions of immunoglobulin D (IgD) and the allergic response." Thesis, University of Sheffield, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370051.

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7

Zhu, Yan [Verfasser]. "Impact of gram-negative bacteria on the allergic immune response in a mouse model of allergen-induced eczema / Yan Zhu." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2010. http://d-nb.info/1025087461/34.

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8

Wang, Junji. "Therapeutic vaccines based on myobacterium vaccae for the treatment of an IgE response to ovalbumin in BALB/c mice." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285207.

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9

McDermott, Jacqueline Ruth. "The influence of dendritic cells on the differentiation of T helper cells." Thesis, University of Surrey, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326509.

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10

Koprich, James B. "Ontogeny of the fetal immune response to maternal smoking in relation to allergic asthma." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ60854.pdf.

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11

Hartmann, Björn Verfasser], and Roland [Akademischer Betreuer] [Lauster. "Vitamin D receptor activation modulates the allergic immune response / Björn Hartmann. Betreuer: Roland Lauster." Berlin : Universitätsbibliothek der Technischen Universität Berlin, 2011. http://d-nb.info/101461953X/34.

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12

Banham, Stephen Walter. "Pigeon breeder's disease : the clinical spectrum and humoral response : an investigation of the nature and extent of extrinsic allergic alveolitis due to pigeon-derived antigens among pigeon fanciers continuing to pursue the pastime, with particular reference to early clinical and humoral-mediated responses following exposure." Thesis, University of Edinburgh, 1986. http://hdl.handle.net/1842/26216.

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13

Deb, Roona. "An investigation of the roles of lung surfactant proteins -A and -D in the pulmonary allergic response." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440148.

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14

Endoh, Ikuko Medical Sciences Faculty of Medicine UNSW. "New mechanisms of regulation of mast cell activation." Publisher:University of New South Wales. Medical Sciences, 2008. http://handle.unsw.edu.au/1959.4/42937.

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Mast cells (MCs) play a central role in inflammation by releasing mediators following activation. S100A8 and S100A9 are abundantly expressed in inflammatory sites such as asthmatic lung, sunburnt skin and atherosclerosis where MCs are involved in pathogenesis; roles of S100A8 in MC function are undetermined. The aims of this thesis were to determine effects of S100A8 on MC activation, particularly provoked by IgE and UVB. Initially, effects of UVB on MC activation were investigated as detailed functions were unclear. Cord blood-derived human mast cells (CBMCs) were treated in vitro with varyin

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15

Macfarlane, Trisha Victoria. "The effect of maternal atopy on chemokine production during pregnancy and at birth, and the production of and response to thymic stromal lymphopoietin in the adult and cord circulation." Thesis, Swansea University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678506.

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16

Sucharew, Heidi. "Item Response Theory and Transition Models Applied to Allergen Skin Prick Testing." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1258560557.

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17

Fan, Ying. "Role of the Axis Th-17/Th-22 in the regulation of the pulmonary immune response in allergic asthma." Thesis, Lille 2, 2013. http://www.theses.fr/2013LIL2S010.

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L'asthme allergique est caractérisé par une réponse prédominante de typeTh2, mais d'autres profils tels que Th17 et Th22 sont aussi observés dans l'asthme plus sévère. La pollution atmosphérique et notamment les hydrocarbures aromatiques polycycliques (HAP) contenus dans les particules d'échappement diesel (DEP) contribuent à l'augmentation de la prévalence de l'asthme et jouent un rôle adjuvant dans le développement et l'exacerbation de l'inflammation allergique en orientant la réponse immune vers un profil Th2Dans la première partie de la thèse, nous avons évalué les effets des HAP sur la po

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18

Bourke, Claire Deirdre. "Human cytokine responses during natural and experimental exposure to parasitic helminth infection." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/9434.

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Over one third of the human population is currently infected by one or more species of parasitic helminth, but the immune responses elicited by these infections remain poorly defined. Studies in helminth-exposed human populations and laboratory models suggest that helminth infection elicits a range of different effector cell types and that protective immunity and resistance to immune-mediated pathology depends on the balance between these responses. The aim of this thesis was to investigate how cytokines, the molecular mediators of the immune system, can be used to characterise human immune ph

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19

Mahay, Guillaume. "Etude de l'initiation de la tolérance de l'immunothérapie spécifique aux venins d'hyménoptères par ultra-rush Ultra-rush venom immunomotherapy induces basophils inhibition by a lower surface expression of FcεRI and leads to early change in innate and adaptive immune response". Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR091.

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L'immunothérapie spécifique (ou désensibilisation) aux venins d'hyménoptères est un traitement qui permet de prévenir la récidive d’une anaphylaxie chez les patients allergiques au venin de guêpe ou d’abeille. Une augmentation très rapide des doses est souvent utilisée lors de la phase initiale de ce traitement dont la bonne tolérance n’est pas bien expliquée. Le but de ce travail était de décrire les changements précoces du système immunitaire pendant l’initiation de l’immunothérapie aux venins d’hyménoptères pouvant expliquer cette bonne tolérance. Nous avons inclus 29 patients traités pour

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20

Kim, Eunsoo. "Epithelial Cells and Gut Microbiota: Role in Allergic Sensitization and Allergic Responses." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1532049862489282.

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21

Camporota, Luigi. "Regulation of inflammatory responses in allergic asthma." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432034.

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22

Brantschen, Stefan. "Hemopoiesis of effector cells involved in allergic responses /." [S.l.] : [s.n.], 1989. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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23

Fallata, Ghaith Mohammed. "Association of gut luminal metabolites and allergic responses." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright1515185113264117.

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24

Gajewska, Beata Urszula Jordana Manel. "Generation of immune responses in experimental allergic airway inflammation /." [Hamilton, Ont.] : McMaster University, 2004.

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25

Brown, Joanna Louise. "Airways inflammation in allergic subjects : responses to air pollution." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403850.

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26

Liu, Bo. "Regulation of Type 2 Immune Responses During Allergic Asthma." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406898945.

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27

Price, Megan. "Sphingosine-1-phosphate in mast cell-mediated allergic responses." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/254.

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Mast cells play a critical role in both acute and chronic inflammation and mature in peripheral tissues from bone marrow-derived progenitors that circulate in the blood as immature precursors. Mast cell progenitors are likely to encounter the serum-borne bioactive sphingolipid metabolite, sphingosine-1-phosphate (S1P), during migration to target tissues. Mast cells developed from human cord blood-derived progenitors cultured with stem cell factor (SCF) alone express intragranular tryptase (MCT), the phenotype predominant in the lung. S1P accelerated the development of cord blood-derived mast c

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28

Du, Tao. "Mechanisms of airway narrowing during allergic responses in the rat." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70170.

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The mechanisms of allergen induced airway narrowing, during allergen induced early (ER) and late (LR) responses, and airway hyperresponsiveness were investigated in vivo using the ovalbumin (OA) sensitized Brown Norway (BN) rat. ER and LR were induced by aerosolized OA. The lungs were fixed using a quick-freezing technique to maintain the pathological alterations as close as possible to their in vivo conditions. The results from both morphologic and morphometric studies showed that during the ER and LR, airway narrowing was mainly caused by airway smooth muscle contraction, but not by airway w

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29

Johansson, Maria A. "Infant gut microbiota, immune responses and allergic disease during childhood." Doctoral thesis, Stockholms universitet, Institutionen för molekylär biovetenskap, Wenner-Grens institut, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-108425.

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The early-life microbiota is important for postnatal immune maturation and implied in immune mediated diseases. The aim of this work was to study specific species of bacteria in the gut microbiota and relate them to immune function and allergic disease during childhood. In paper I we investigated gut bacteria in feces from infants included in a prospective allergy cohort. We found that children with non-allergic parents were more likely to be colonized with a group of lactobacilli. Further, lactobacilli colonization was more prevalent in children remaining non-allergic, regardless of allergic

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30

Salazar, F. "The role of indoleamine 2,3-dioxygenase in modulating allergic responses." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33071/.

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Dendritic cells (DCs) are key players in the induction and re-elicitation of T helper (Th) 2 immune responses to allergens. Recent data by our group have shown that different C-type lectin receptors (CLRs) on DCs play a major role in allergen recognition and uptake. Particularly, mannose receptor (MR), through modulation of Toll-like receptor (TLR) 4 signalling pathway, can regulate indoleamine 2,3 dioxygenase (IDO) activity favouring Th2 responses. IDO is the rate limiting enzyme involved in tryptophan (TRP) catabolism and it is well known for its role in modulating immune responses through T

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31

Minang, Jacob. "Cytokine responses in metal-induced allergic contact dermatitis : Relationship to in vivo responses and implication for in vitro diagnosis." Doctoral thesis, Stockholm : Dept. of Immunology, Wenner-Gren Institute, Stockholm University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-717.

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32

Tomičić, Sara. "Environmental and immunological factors associated with allergic disease in children." Doctoral thesis, Linköpings universitet, Pediatrik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11615.

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Background: Allergic diseases are characterised by dysregulated immune responses. The first manifestation of the atopic phenotype is often food allergy, with symptoms like eczema. Food allergy in children is generally outgrown before 3 years of age, but a temporary food elimination diet is often advocated. The prevalence of allergic diseases has increased in affluent countries during the last decades, possibly as a consequence of a changed lifestyle leading to decreased microbial load. Aim: To investigate humoral, mucosal and cell-mediated immunity in association to allergy and allergy develop

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33

Masjedi, Khosro. "In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy." Doctoral thesis, Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm university, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7685.

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34

Archila, Diaz Luis Diego. "Assessment of allergen specific response in humans." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/310215.

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Allergies are emerging as a major public health concern in the westernized world as they are increasing for reasons that remain poorly understood. Allergies involving polysensitization and multiple organ involvement result in decreased quality of life, increased morbidity and mortality. Allergic subjects can be poly-sensitized to different allergens due to phylogenetic relatedness; several species contain shared allergenic epitopes. This phenomenon occurs both at the IgE as the T cell level. While IgE cross-reactivity has been well documented, T-cell cross-reactivity has not been thoroughly st

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35

Gardner, Leanne M. (Leanne Margaret) 1977. "Modulation of the allergen-specific Tcell response." Monash University, Dept. of Pathology and Immunology, 2003. http://arrow.monash.edu.au/hdl/1959.1/5817.

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36

Hayes, Tristan Alonzo. "Characterizing the Innate Immune Response of Human Airway Cells to the Unique Fungal Allergen Alt a 1." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/85399.

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Allergic airway diseases such as rhinitis, asthma, and chronic rhinosinusitis are responsible for causing a huge economic burden on patients and society. Patients suffering from asthma often have allergies to pollen, dust mite, and mold. Interestingly, studies have shown that there is a correlation between severe asthma and sensitization to fungi including Aspergillus, Alternaria, Cladosporium, and Penicillium. This project has been focused on studying the innate immunomodulatory activities of the major allergen Alt a 1, from the ubiquitous airborne fungus, Alternaria alternata. In several stu

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37

Kirstein, Frank. "Investigations of immune responses in different mouse models of allergic asthma." Doctoral thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/3171.

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Johansson, Maria. "Early gut microbiota in relation to cytokine responses and allergic disease." Licentiate thesis, Stockholms universitet, Avdelningen för immunologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-56337.

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39

Koch, Christin. "Immunomodulation of the IgE dependent immune response by docosahexaenoic acid." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2009. http://dx.doi.org/10.18452/15927.

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Der globale Prävalenzanstieg allergischer Erkrankungen wird mit der westlichen Ernährung und einem sich ändernden Fettsäurespektrum assoziiert. Die omega-3 Fettsäure Docosahexaensäure (DHA) wurde bereits bei verschiedenen chronisch-entzündlichen Erkrankungen erfolgreich therapeutisch eingesetzt. Die dabei zugrunde liegenden Wirkmechanismen sind jedoch nicht vollständig geklärt. Deshalb wurde hier der molekulare Mechanismus der DHA-vermittelten Hemmung der IgE-Produktion in humanen B-Zellen sowie der verminderten Differenzierung IgE-produzierender Plasmazellen in vitro untersucht. Analysen der

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40

Sutherland, Michael F. (Michael Fraser) 1967. "The human immune response to the latex allergen Hev b 5." Monash University, Dept. of Pathology and Immunology, 2003. http://arrow.monash.edu.au/hdl/1959.1/7750.

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41

Warstedt, Kristina. "Polyunsaturated fatty acids, maternal and infant immune responses and allergic disease in infancy." Doctoral thesis, Linköpings universitet, Pediatrik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-56265.

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Background: The incidence of allergic diseases in industrialized countries has increased, and a relation between allergy and dietary fatty acids has been proposed. Modulation of the maternal immune function during pregnancy may have an impact on future clinical outcome in the child. Aim: The aim of this thesis was to add knowledge on the relationship between long chain polyunsaturated fatty acids, sensitization and allergic disease and possible immunological events regulating this. Subjects: The thesis is based on results obtained from two cohorts. The first, including 300 cord blood samples c

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42

Allakhverdieva, Zoulfia. "Modulation of airway responses to antigen in a rat model of allergic asthma." [Montréal] : Université de Montréal, 2002. http://wwwlib.umi.com/cr/umontreal/fullcit?pNQ73468.

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Thèse (Ph. D.)--Université de Montréal, 2002.<br>"NQ-73468." "Thèse présentée à la faculté des études supérieures en vue de l'obtention du grade de philosophiae doctor (Ph. D.) en sciences biomédicales." Version électronique également disponible sur Internet.

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43

Dzidic, Majda. "Microbiota development and mucosal IgA responses during childhood in health and allergic disease." Doctoral thesis, Universitat Politècnica de València, 2019. http://hdl.handle.net/10251/125479.

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[ES] Antecedentes: Los patrones de colonización microbiana alterados durante la infancia pueden ser en parte responsables del aumento de enfermedades alérgicas en los países desarrollados. La microbiota intestinal difiere en composición y diversidad durante los primeros meses de vida en niños que luego desarrollan o no una enfermedad alérgica. Sin embargo, poco se sabe sobre la importancia de las respuestas inmunitarias tempranas de la mucosa a la microbiota intestinal en el desarrollo de alergias infantiles. Además, los estudios con respecto al efecto protector de la microbiota de la leche ma

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44

Polosa, Riccardo. "The mechanism of bradykinin-induced bronchoconstriction in asthma." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295948.

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Barck, Charlotte. "Airway responses to NO₂ and allergen in asthmatics /." Stockholm : Karolinska University Press, 2005. http://diss.kib.ki.se/2005/91-7140-273-X/.

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46

Evans, David John. "Inflammatory mechanisms in late asthmatic responses to allergen challenge." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267694.

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Campbell, Emma Michelle. "The role of RANTES in guinea pig inflammatory responses." Thesis, University of Bath, 1996. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362252.

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Chowdhury, Pratiti Home. "PM2.5 components and respiratory allergy： a series of in vitro studies focusing Asian cities." Kyoto University, 2017. http://hdl.handle.net/2433/227613.

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Smith, Lance Malcolm. "An experimental investigation of the cutaneous late phase response in humans." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295707.

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Amoudruz, Petra. "Maternal immune characteristics and innate immune responses in the child in relation to allergic disease." Doctoral thesis, Stockholms universitet, Wenner-Grens institut, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7818.

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The mechanistic factors responsible for the increase in allergic diseases are still not fully understood, but a reduced microbial stimulation seems to be one of the key issues. Research is now aiming at investigating the relationship between the innate immune system, involving the toll-like receptors, and allergy development. Further, the maternal influence on the child, possibly through in utero effects, but also through the breast milk, has shown to be of great importance. This thesis aimed at understanding how the maternal immune system is influenced by early exposures and allergic disease,

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