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Rozprawy doktorskie na temat „Allogeneic hematopoietic cell transplantation”

Autor: Grafiati
Data publikacji: 2 czerwca 2025
Data aktualizacji: 31 lipca 2025

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1

Omazic, Brigitta. "Immune reconstitution after allogeneic hematopoietic stem cell transplantation /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-117-2/.

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Onda, Yoshiyuki. "Adenovirus infection after allogeneic hematopoietic stem cell transplantation." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/265191.

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京都大学<br>新制・課程博士<br>博士(医学)<br>甲第23419号<br>医博第4764号<br>新制||医||1052(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 滝田 順子, 教授 杉田 昌彦, 教授 朝長 啓造<br>学位規則第4条第1項該当<br>Doctor of Medical Science<br>Kyoto University<br>DFAM
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Aboalela, Ali Anwar. "Immune Reconstitution of B Cells Following Allogeneic Hematopoietic Cell Transplantation." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17331949.

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Objectives: Graft versus host disease (GVHD), infections and disease relapse continue to be major complications of allogeneic hematopoietic cell transplantation (HCT). B cell abnormalities have been associated with these complications, and the objective of these studies was to identify and quantify abnormalities of B cell recovery after allogeneic HCT. Methods: Flow cytometry was used to analyze peripheral blood from healthy donors (HD) and samples obtained at 1, 2, 3, 6, 9, 12, 18, 24, 30, and 36 months post HCT. A panel of 8 fluorophore-conjugated monoclonal antibodies specific for B cell su
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Okas, Mantas. "Novel immunotherapeutical strategies in allogeneic hematopoietic stem cell transplantation /." Stockholm : Department of laboratory medicine, Karolinska institutet, 2010. http://diss.kib.ki.se/2010/978-91-7409-934-8/.

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Wang, Fu-Zhang. "Human herpesvirus 6 infection after allogeneic stem cell transplantation /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3589-0/.

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Al-Ali, Haifa Kathrin. "The impact of the age of HLA-identical siblings on mobilization and collection of PBSCs for allogeneic hematopoietic cell transplantation." Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-171123.

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Through the recruitment of immunologic mechanisms, allogeneic hematopoeitic cell transplantation (HCT) has been establiched as a curative treatment for various hematologic diseases. The most convenient source to obtain hematopoietic progenitor cells are peripheral blood stem cells (PBSCs) which are harvested from the donor via leukapheresis after mobilization with granulocyte-colony stimulating factors. With the introduction of reduced intensity condition (RIC), the curative potential of allogeneic HCT became accessible to older and/or frail patients otherwise ineligible for HCT. However, new
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Rascon, Jelena. "Chimerism analysis in isolated cell populations after allogeneic hematopoietic stem cell transplantation in children." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090526_111155-01916.

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The doctoral thesis aimed to evaluate in a comparative way the benefit chimerism assessment in isolated cell populations (ICP) versus conventional monitoring in whole blood cells (WBC). The study was initiated in Pediatric Bone Marrow Transplant Service of Charité Children’s Hospital (Humboldt University, Berlin). Children suffered from: acute lymphoblastic leukemia (ALL), Fanconi anemia (FA) and adrenoleukodystrophy (ALD) were included into the study. Thereafter the doctoral thesis was accomplished at the Vilnius University where evaluation of the own experience of chimerism analysis in pedia
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Mattsson, Jonas. "Molecular monitoring of engraftment and leukemia relapse after allogeneic hematopoietic stem cell transplantation /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4757-0/.

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Thiede, Christian, Martin Bornhäuser, and Gerhard Ehninger. "Strategies and Clinical Implications of Chimerism Diagnostics after Allogeneic Hematopoietic Stem Cell Transplantation." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-137505.

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Analysis of donor chimerism has become a routine method for the documentation of engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years several groups have also focused on the application of this technique for the detection of relapsing disease after allogeneic HSCT. This review addresses technical issues (sensitivity, specificity) and discusses the advantages and limitations of methods currently used for chimerism analysis and their usefulness for the detection of MRD. In addition, the potential impact of novel procedures, e.g. subset chimerism or real-ti
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Thiede, Christian, Martin Bornhäuser, and Gerhard Ehninger. "Strategies and Clinical Implications of Chimerism Diagnostics after Allogeneic Hematopoietic Stem Cell Transplantation." Karger, 2004. https://tud.qucosa.de/id/qucosa%3A27736.

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Analysis of donor chimerism has become a routine method for the documentation of engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years several groups have also focused on the application of this technique for the detection of relapsing disease after allogeneic HSCT. This review addresses technical issues (sensitivity, specificity) and discusses the advantages and limitations of methods currently used for chimerism analysis and their usefulness for the detection of MRD. In addition, the potential impact of novel procedures, e.g. subset chimerism or real-ti
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11

GAMBACORTA, VALENTINA. "Novel Insights into the Immunobiology of Leukemia Relapse after Allogeneic Hematopoietic Cell Transplantation." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/259336.

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Il numero di pazienti affetti da leucemia mieloide acuta (LMA) trattati con trapianto di cellule ematopoietiche allogeniche (TCE-allo) è in costante aumento. L'efficacia terapeutica di questa procedura si basa principalmente sul trasferimento dal donatore al paziente di cellule immunitarie, in grado di riconoscere ed eliminare le cellule tumorali residue. Tuttavia, fino al 50% dei pazienti trapiantati con LMA va incontro a recidiva e la prognosi di questi pazienti rimane estremamente negativa. Pertanto, lo scopo del mio lavoro di tesi era quello di migliorare la comprensione attuale dell'immun
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Uzunel, Mehmet. "The methodology and significance of minimal residual disease detection after allogeneic stem cell transplantation /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-619-7.

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Hägglund, Hans. "Risk-factors, prevention and treatment of early complications after allogeneic haematopoietic stem cell transplantation /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-3034-1/.

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Karaesmen, Ezgi. "Genetic Associations with Survival Outcomes after Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1587686582370275.

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Shindo, Takero. "Growth and differentiation advantages of CD4[+]OX40[+] T cells from allogeneic hematopoietic stem cell transplantation recipients." Kyoto University, 2008. http://hdl.handle.net/2433/135836.

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Tay, Jason. "Donor selection for patients undergoing allogeneic hematopoietic stem cell transplantation: Assessment of the priorities of Canadian hematopoietic stem cell transplant physicians." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28202.

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Allogeneic Hematopoietic Stem Cell Transplantation is applied in the management of cancer. It involves myeloablative chemoradiotherapy followed by infusion of donor stem cells. The characteristics of the donor stern cells influences transplant outcomes which itself, is dependent on the donor characteristics. The purpose of this thesis was to explore preferences over donor characteristics. A systematic review was performed to identify all donor characteristics associated with outcome. Eight traditional and 5 non-traditional characteristics were identified. The results of the review were used to
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Rizvi, Abbas Ali. "Genetic Associations in Acute Leukemia Patients after Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555285409458706.

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18

Fu, Jianing. "Targeting T-bet for Prevention of Graft-Versus-Host Disease and Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5828.

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Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective therapeutic option for many malignant diseases. However, the efficacy of allo-HSCT is limited by the occurrence of destructive graft-versus-host disease (GVHD). Since allogeneic T cells are the driving force in the development of GVHD, their activation, proliferation, and differentiation are key factors to understanding GVHD pathogenesis. On the other hand, antigen-presenting cells (APCs) are essential for allogeneic T-cell priming and the development of GVHD. The T-box transcription factor T-bet is a master regulat
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19

Larsson, Kajsa. "Cytomegalovirus after allogeneic haematopoietic stem cell transplantation : complications in the era of CMV-specific antiviral treatment /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-735-5/.

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Jaksch, Marie. "Molecular monitoring of acute graft-versus-host disease after allogeneic stem cell transplantation /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-987-0/.

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Diedrich, Beatrice. "Storage and transfusion of platelets in vitro and in vivo studies in healthy volunteers and in allogeneic hematopoetic progenitor cell transplant recipients /." Stockholm : Karolinska institutet, 2009. http://diss.kib.ki.se/2009/978-91-7409-280-6/.

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Seung, Edward. "CD40-CD154 Blockade Facilitates Induction of Allogeneic Hematopoietic Chimerism and Transplantation Tolerance: A Dissertation." eScholarship@UMMS, 2003. https://escholarship.umassmed.edu/gsbs_diss/103.

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Allogeneic hematopoietic chimerism leading to central tolerance has significant therapeutic potential. Establishment of hematopoietic chimerism created by stem cell transplantation has been shown to prevent and cure a number of autoimmune diseases and induce the most robust and long-lasting form of transplantation tolerance known. However, the realization of the vast clinical potential of hematopoietic chimerism for induction of transplantation tolerance has been impeded by the toxicity of the host conditioning regimen and the development of graft-versus-host disease (GVHD). This thesis descri
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Hentschke, Patrik. "Anti-tumour effect in solid tumours, tolerance and immune reconstitution after allogeneic haematopoietic stem cell transplantation /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-800-9/.

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Robien, Kimberly Ziemer. "Folate status and risk of relapse following allogeneic hematopoietic cell transplant for chronic myelogenous leukemia /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/6598.

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Gustafsson, Jernberg Åsa. "Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-439-9/.

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Lesnoski, Bryant P. "The Role of Nutrition Assessment in the Indication of Gastrointestinal Complications in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1563525591746257.

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Kelly, Debra. "Symptoms, Cytokines, and Quality of Life of Patients with Chronic Graft-versus-Host Disease following Allogeneic Hematopoietic Stem Cell Transplantation." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3359.

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Introduction: Chronic graft-versus-host disease (cGVHD) is a serious complication following allo-HSCT characterized by immune dysregulation, organ dysfunction, risk for infection, and distressing symptoms. Complications may include scleroderma, hepatic dysfunction and bronchiolitis obliterans. Advances in allo-HSCT for many hematologic dyscrasias (e.g. acute and chronic leukemias, aplastic anemia, and myelodysplastic syndrome) have improved survival which has generated a renewed focus on survivorship issues. Distressing symptoms are noted as negatively impacting quality of life (QoL). The rela
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RAMBALDI, BENEDETTA. "Understanding T and NK cell reconstitution after allogeneic hematopoietic cell transplantation: a path to improve graft versus leukemia and minimize graft versus host disease." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2023. https://hdl.handle.net/10281/402375.

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Il trapianto di cellule ematopoietiche (HCT) rappresenta una terapia cardine per il trattamento delle neoplasie ematologiche altrimenti incurabili. Tuttavia, la procedura di trapianto può essere gravata dalla recidiva della malattia, dalla malattia del trapianto contro l'ospite (GVHD) e dalle infezioni. Le cellule T e NK che ricostituiscono dopo l'HCT proteggono da infezioni e recidive, ma sono anche coinvolte nella patogenesi della GVHD. Gli obiettivi del mio progetto di dottorato erano di migliorare la comprensione della ricostituzione delle cellule T e NK, utilizzando campioni di donatori s
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Fleischhauer, Katharina [Akademischer Betreuer]. "Innovative approaches to the detection of HLA immune escape in leukemia relapse after allogeneic hematopoietic stem cell transplantation / Betreuer: Katharina Fleischhauer." Duisburg, 2018. http://d-nb.info/1162056878/34.

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Torregrossa, Vinicius Rabelo 1987. "A influência do transplante de células-tronco hematopoéticas alogênico no fluxo salivar = The influence of allogeneic hematopoietic stem cell transplantation on salivary flow." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288069.

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Orientador: Maria Elvira Pizzigatti Corrêa<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-27T08:02:08Z (GMT). No. of bitstreams: 1 Torregrossa_ViniciusRabelo_M.pdf: 2074120 bytes, checksum: 7ac320774930da79cb9aea0a6c37ec73 (MD5) Previous issue date: 2015<br>Resumo: INTRODUÇÃO: Alterações salivares quantitativas e qualitativas são complicações comuns ao Transplante de Células-Tronco Hematopoiéticas alogênico (TCTHa). Essas alterações salivares são frequentemente relacionas à fase tardia do TCTHa, pri
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Tumino, Manuela Rossella. "Espressione genica e Profilo Fosfoproteomico nella Malattia del Trapianto contro l Ospite in bambini sottoposti a trapianto di cellule staminali ematopoietiche: confronto tra forma acuta e forma cronica." Doctoral thesis, Università di Catania, 2013. http://hdl.handle.net/10761/1375.

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La malattia del trapianto contro l ospite (Graft versus Host Disease, GvHD), principale complicanza del trapianto allogenico di cellule staminali ematopoietiche (alloTCSE), è un disordine immunologico scatenato dai linfociti T del donatore contro gli alloantigeni del ricevente; la gravità dipende dalle differenze HLA tra donatore e ricevente, con interessamento di diversi organi (cute, tratto gastrointestinale, fegato, polmoni). Si distinguono la forma acuta e cronica (aGvHD, cGvHD). Le conoscenze sulla patogenesi della forma acuta sono meglio conosciute rispetto a quelle sulla cGvHD, in cui
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Watanabe, Mizuki. "Analysis of factors that have impacts on various infectious diseases after allogenic hematopoietic stem cell transplantation." Kyoto University, 2020. http://hdl.handle.net/2433/253195.

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Manickam, Arun Kumar [Verfasser], and Michael [Akademischer Betreuer] Reth. "Development of a new mouse host for (syngeneic, allogeneic and xenogeneic) hematopoietic cell transplantations without lethal irradiation as preconditioning." Freiburg : Universität, 2018. http://d-nb.info/117907520X/34.

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VINCI, PAOLA. "From understanding the molecular basis of Graft-versus-Host Disease (GvHD), to new diagnostic tools and innovative treatments for improving the management of patients undergoing allogeneic Hematopoietic Stem Cell Transplantation (HSCT)." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50969.

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Allogeneic haematopoietic-stem-cell transplantation (HSCT) is the treatment of choice for many malignant and non-malignant disorders. The development of novel strategies such as donor leukocyte infusion, nonmyeloablative HSCT, and cord blood transplantation allowed expanding the indications for allogeneic HSCT over the last several years, especially among older patients. However, the major toxicity of allogeneic HSCT, Graft-versus-Host Disease (GvHD), remains a complication that limits its wider application. Despite advances in post-transplantation immunosuppressive therapy, GvHD remains a maj
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Araújo, Beatriz Stela Gomes de Souza Pitombeira. "Validação do escore de risco do EBMT (European Group for Blood and Marrow Transplantation) na população de pacientes submetidos ao transplante de células-tronco hematopoéticas no Hospital de Clínicas de Porto Alegre." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/48996.

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INTRODUÇÃO: O Transplante de Células-tronco Hematopoéticas (TCTH) alogênico é uma modalidade de tratamento com capacidade de curar várias doenças hematológicas benignas e malignas. Os progressos nesta área aumentaram o número e melhoraram os desfechos dos procedimentos realizados, porém sua morbimortalidade permanece elevada. Em 2009, o escore de risco do EBMT foi validado como um método simples para predizer, com dados pré-transplante, os desfechos de um paciente após o TCTH alogênico. OBJETIVOS: O objetivo deste estudo foi validar a aplicabilidade do escore de risco do EBMT em pacientes bras
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Costa, Brunno Câmara Lopes. "Pesquisa de bocavírus humano em pacientes submetidos a transplante alogênico de células progenitoras hematopoiéticas." Universidade Federal de Goiás, 2018. http://repositorio.bc.ufg.br/tede/handle/tede/8910.

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Al-Ali, Haifa Kathrin [Verfasser], Christoph [Gutachter] Baerwald, and Thomas [Gutachter] Berg. "The impact of the age of HLA-identical siblings on mobilization and collection of PBSCs for allogeneic hematopoietic cell transplantation : The impact of the age of HLA-identical siblings onmobilization and collection of PBSCs for allogeneichematopoietic cell transplantation / Haifa Kathrin Al-Ali ; Gutachter: Christoph Baerwald, Thomas Berg." Leipzig : Universitätsbibliothek Leipzig, 2015. http://d-nb.info/1239566492/34.

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Bäßler, Maya Thordis [Verfasser]. "Einfluss von Komorbiditäten, gemessen mit dem Hematopoietic cell transplantation-specific comorbidity index (HCT-CI), auf das Überleben nach allogener Stammzelltransplantation / Maya Thordis Bäßler." Köln : Deutsche Zentralbibliothek für Medizin, 2012. http://d-nb.info/1032265973/34.

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Lemes, Lucianna Gonçalves Nepomuceno. "Estudo prospectivo de infecção por calicivírus (norovírus e sapovírus) em pacientes submetidos a transplante alogênico de células progenitoras hematopoiéticas." Universidade Federal de Goiás, 2013. http://repositorio.bc.ufg.br/tede/handle/tede/3177.

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Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-09-25T17:34:38Z No. of bitstreams: 2 Dissertação_Lucianna G. N. Lemes.pdf: 2661301 bytes, checksum: c0238e41dfbe2adbd10e5ddcff7a139e (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2014-09-26T11:31:18Z (GMT) No. of bitstreams: 2 Dissertação_Lucianna G. N. Lemes.pdf: 2661301 bytes, checksum: c0238e41dfbe2adbd10e5ddcff7a139e (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Made availab
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Luiz, Ana Cláudia. "Alterações bucais em pacientes submetidos ao transplante de células tronco hematopoiéticas: estudo longitudinal." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/23/23141/tde-13092012-112209/.

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A boca é local de frequentes complicações relacionadas ao transplante de células tronco hematopoiéticas (TCTH) tais como xerostomia, disgeusia, disfagia, mucosite, infecções oportunistas e doença do enxerto contra hospedeiro (DECH). Sabe-se que estas complicações podem comprometer a qualidade de vida do paciente e interferir na morbidade pós-TCTH. O dentista é o profissional da saúde que deverá intervir no momento correto para tratar e minimizar esses efeitos secundários do TCTH. Para tanto é importante conhecermos o momento em que cada complicação ocorre para que a intervenção seja pronta e e
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Furlanetto, Marina de Almeida. "Transplante alogênico de medula óssea x terapia de consolidação com quimioterapia em pacientes portadores de leucemia mielóide aguda de risco intermediário em 1ª remissão completa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/139791.

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Introdução: O Transplante Alogênico de Célula Tronco Hematopoiética (TCTH alogênico) é um procedimento de alto potencial curativo para a Leucemia Mielóide Aguda (LMA), principalmente pelo efeito “graft versus leukemia” (GVL), que leva a redução do risco de recaída. Atualmente, os pacientes com LMA de risco intermediário são submetidos ao procedimento caso possuam doador aparentado. Pacientes sem doador aparentado disponível são submetidos a tratamento de consolidação com quimioterapia, com maior chance de recaída da doença. Acredita-se que os pacientes submetidos ao TCTH tenham maiores sobrevi
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Leclerc, Mathieu. "Modulation de l’effet des lymphocytes T régulateurs par la voie TNFα/TNFR2 : une nouvelle immunothérapie en allogreffe de cellules souches hématopoïétiques". Thesis, Paris Est, 2017. http://www.theses.fr/2017PESC0014/document.

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Les lymphocytes T régulateurs (Treg) jouent un rôle majeur dans la modulation de l’alloréactivité après allogreffe de cellules souches hématopoïétiques et permettent notamment de contrôler la réaction du greffon contre l’hôte (GVH) dans des modèles expérimentaux. Le potentiel thérapeutique des Treg est donc très important dans ce domaine, mais aussi dans l’auto-immunité ou en cancérologie. Cependant, de nombreuses barrières rendent difficile l’élaboration de stratégies thérapeutiques reposant sur le transfert adoptif de Treg chez l’homme et une meilleure compréhension des facteurs et mécanisme
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Cardozo, Daniela Maira 1984. "Importância das disparidades genéticas nos genes HLA e KIR na resposta de pacientes submetidos ao transplante alogênico de células progenitoras hematopoiéticas para o tratamento de doenças onco-hematologicas = Importance of genetic differences in HLA and KIR genes in the response of patients undergoing allogeneic hematopoietic stem cell transplantation for treatment of onco-hematological diseases." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308649.

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Orientadores: Cármino Antonio de Souza, Jeane Eliete Laguila Visentainer<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-22T17:20:39Z (GMT). No. of bitstreams: 1 Cardozo_DanielaMaira_D.pdf: 3033896 bytes, checksum: b4696b2dc5fc0ec422091c74289aed9f (MD5) Previous issue date: 2013<br>Resumo: No organismo humano, as moléculas HLA (Human Leukocyte Antigens) são proteínas expressas na superfície da maioria das células nucleadas e são codificadas por genes localizados no braço curto do cromossomo 6 na região do Complexo
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Nadal-Melsio, Elisabet. "Regulatory T cells after allogeneic stem cell transplantation." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523746.

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Ortí, Pascual Guillermo. "Analysis of Donor Lymphocyte Infusions after Allogeneic Hematopoietic Cell Transplant." Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/673246.

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El trasplantament al·logènic de cèl·lules hematopoètiques (AloTPH) és una estratègia terapèutica major per al tractament de neoplàsies malignes hematològiques. Mitjançant l’efecte d’empelt contra leucèmia que aporta el AloTPH s’aconsegueixen respostes completes mantingudes. No obstant, la recaiguda segueix sent la complicació més important després de l’AloTPH. En aquest context, l’ús d’infusions de limfòcits de donants (ILD) o un segon AlloHCT (TPH2) són estratègies essencials per millorar la supervivència. Diversos treballs han estudiat l’efectivitat i la toxicitat de les DLI, però la respost
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Barata, Badiella Anna. "Quality of life in hematopoietic cell transplantation." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/402219.

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El trasplantament al·logènic de progenitors hematopoètics (TPH) és la principal opció curativa per diverses neoplàsies hematològiques tot i que comporta una morbiditat física i psicològica significativa. L’objectiu de la tesi és avaluar la qualitat de vida, la depressió, les estratègies d’afrontament de problemes i les necessitats psicosocials en receptors de TPH al·logènic i els seus cuidadors. Els participants són receptors adults de TPH al·logènic que havien rebut un TPH en el Moffitt Cancer Center (Tampa, Estats Units) i els seus cuidadors. Els resultats s’han analitzat mitjançant
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Li, Pulin. "Chemical Genetics of Hematopoietic Stem Cell Transplantation." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10306.

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Hematopoietic stem and progenitor cells (HSPCs) repopulate the blood system upon transplantation. A large-scale genetic approach to understand the factors that participate in successful engraftment has not been undertaken. In this thesis, I present the development of a novel live imaging-based competitive marrow repopulation assay in adult zebrafish, which allows fast and quantitative measurement of HSPC engraftment capability. Using this assay, a transplantation-based chemical screen was performed, which led to the discovery of 10 compounds that can enhance the marrow engraftment capability i
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Fallen, Paul Raymond. "Reconstitution of the T-cell compartment post-allogeneic haematopoietic cell transplantation." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268750.

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Xiong, Ying. "Immuno-Magnetic T Cell Depletion For Allogeneic Hematological Stem Cell Transplantation." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1205852981.

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Remberger, Mats. "Cytokine production in allogeneic haematopoietic stem-cell transplantation patients /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3749-4/.

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