Artykuły w czasopismach: „Anabolic drugs”

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Williamson, K. "Misuse of anabolic drugs." BMJ 306, no. 6875 (1993): 459. http://dx.doi.org/10.1136/bmj.306.6875.459-a.

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Corsini, Emanuela, Antonella Pinto, Valentina Galbiati, and Marco Racchi. "Immunomodulatory effects of anabolic drugs." Toxicology Letters 229 (September 2014): S20. http://dx.doi.org/10.1016/j.toxlet.2014.06.107.

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DuRant, Robert H., Luis G. Escobedo, and Gregory W. Heath. "Anabolic-Steroid Use, Strength Training, and Multiple Drug Use Among Adolescents in the United States." Pediatrics 96, no. 1 (1995): 23–28. http://dx.doi.org/10.1542/peds.96.1.23.

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Objective. This study examined the relationships between anabolic-steroid use and the use of other drugs, sports participation, strength training, and school performance among a nationally representative sample of US high school students. Design. Randomized survey data from the 1991 Centers for Disease Control and Prevention Youth Risk Behavior Survey. Setting. Public and private schools in the 50 United States and District of Columbia. Patients. A total of 12 272 9th through 12th grade students. Main Outcome Measured. Prevalence of anabolicsteroid use. Results. The frequency of anabolic-stero

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De Brabander, H. F., K. Verheyden, V. Mortier, et al. "Phytosterols and anabolic agents versus designer drugs." Analytica Chimica Acta 586, no. 1-2 (2007): 49–56. http://dx.doi.org/10.1016/j.aca.2006.07.031.

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Stanley, A., and M. Ward. "5. Anabolic Steroids — The Drugs That Give and Take Away Manhood. A Case with an Unusual Physical Sign." Medicine, Science and the Law 34, no. 1 (1994): 82–83. http://dx.doi.org/10.1177/002580249403400115.

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A case is presented in which the abuse of anabolic steroids by a body builder led to an unusual physical sign. The case discusses the effects that anabolic steroid abuse can have upon manhood. The frequency of anabolic steroid misuse is increasing. The implications of this with respect to psychiatric illness and violent crime are discussed. It is well known that the use of anabolic steroids among young men, body builders in particular, is growing apace (Perry and Littlepage, 1992), and they may be aware of the risks of impurity and contamination. There is a wide range of anabolic steroids in u

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Nikolic, Bozana, and Dusica Rakic. "The use of anabolic androgenic steroids: A focus on polypharmacy." Medical review 71, no. 11-12 (2018): 413–17. http://dx.doi.org/10.2298/mpns1812413n.

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Introduction. Anabolic androgenic steroids, such as testosterone and its synthetic analogue, nandrolone, have clear clinical indications. However, their abuse is practiced to enhance physical performance in professional, recreational and non-professional athletes; outside of sports, their nonmedical use is associated with different social groups (criminal activities, substance abuse). Polypharmacy. Testosterone and its synthetic analogues are also used for nonmedical purposes, mainly administered in supraphysiological doses in cycles lasting a few weeks. In order to potentiate the anabolic pro

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Salave, Sagar, Dhwani Rana, and Derajram Benival. "Peptide Functionalised Nanocarriers for Bone Specific Delivery of PTH (1-34) in Osteoporosis." Current Nanomedicine 11, no. 3 (2021): 142–48. http://dx.doi.org/10.2174/2468187312666211220112324.

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: Osteoporosis represents a major public health burden especially considering the aging population worldwide. Treatment modalities for osteoporosis are classified into two categories based on the effect on bone remodelling: anabolic drugs and antiresorptive drugs. Anabolic drugs are preferred as it stimulates new bone formation. Currently, PTH (1-34) is the only peptide-based drug approved as an anabolic agent for the treatment of osteoporosis by both USFDA as well as EMA. However, its non-specific delivery results in prolonged kidney exposure, causing hypercalcemia. Nanotechnology-based drug

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Shapiro, Jonathan, Joseph Christiana, and William H. Frishman. "Testosterone and Other Anabolic Steroids as Cardiovascular Drugs." American Journal of Therapeutics 6, no. 3 (1999): 167–74. http://dx.doi.org/10.1097/00045391-199905000-00008.

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Rizzoli, René. "Combined and sequential therapies with anabolic and antiresorptive drugs in the management of patients with postmenopausal osteoporosis." International Journal of Bone Fragility 3, no. 1 (2023): 7–15. http://dx.doi.org/10.57582/ijbf.230301.007.

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The aim of osteoporosis therapy is to reduce the increased fracture risk associated with osteoporosis-related bone fragility. Prevention of fragility fracture relies on balanced nutrition, weight-bearing and balance-improving physical exercises, and pharmacological therapies. Among the latter, the antiresorptive drugs are the most widely used. Bone formation stimulators (anabolics) are second line-therapy with reversible effects once discontinued. For patients at very high risk or imminent risk of fracture, the question arises of whether combining drugs with different modes of action, or using

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Dawson, RT. "Drugs in sport - the role of the physician." Journal of Endocrinology 170, no. 1 (2001): 55–61. http://dx.doi.org/10.1677/joe.0.1700055.

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Sportsmen have used anabolic steroids since the 1950s and yet it was not until the 1980s that we, as physicians, admitted that they could improve performance. We now find ourselves in the insidious position of being unable to predict convincingly either safety or major health risks with performance-enhancing drug use. The use of performance-enhancing drugs is no longer limited to the elite athlete. In 1993 the Canadian Center for Drug-free Sport estimated that 83 000 children between the ages of 11 and 18 had used anabolic steroids in the previous 12 months. Recent evidence suggests anabolic s

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Carolin, Ribka, Basuki Supartono, and Yanto Sandy Tjang. "Efficacy of Osteoporosis Drugs Anabolic and Antiresorptive Classes in Post Menopause Women." Saintika Medika 17, no. 2 (2021): 112–23. https://doi.org/10.22219/sm.vol17.smumm2.15595.

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Osteoporosis is a degenerative bone disease that affects many postmenopausal women. Antiosteoporosis drugs consist of antiresorptive and anabolic groups. So far, there is still controversy over the administration of antiosteoporosis drugs, therefore researchers conducted a systematic review study aimed at determining which one is more effective. This research was conducted by reviewing several studies through the PubMed and Science Direct databases. The results showed that abaloparatide, teriparatide, and SERM (Selective Estrogen Receptor Modulators) were more effective than bisphosphonates. I

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Cecoro, G., M. Paoletta, M. Annunziata, et al. "The role of bone anabolic drugs in the management of periodontitis: a scoping review." European Cells and Materials 41 (March 18, 2021): 316–31. http://dx.doi.org/10.22203/ecm.v041a20.

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The aim of this scoping review was to summarise current knowledge about the effects of bone anabolic drugs on periodontitis, in order to identify new therapeutic strategies for preventing disease progression and reducing tooth loss. A technical expert panel (TEP) was established of 11 medical specialists, including periodontists and bone specialists that followed the PRISMA-ScR model to perform the scoping review and considered for eligibility both pre-clinical and clinical studies published in the English language up to September 2020. 716 items were initially found. After duplicate removal a

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Amedovski, Haris, and Denis Arsovski. "Use of legal and illegal performance enhancing drugs and supplements in gym users." Hrvatski športskomedicinski vjesnik 40, no. 1 (2025): 50–58. https://doi.org/10.69589/hsv.40.1.5.

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The use of performance-enhancing substances such aslegal supplements and illegal anabolic agents has becomecommon among recreational athletes. This research aimedto assess the prevalence, satisfaction, motivations, andhealth risks associated with such substances among gymusers.A quantitative, cross-sectional study was conductedusing a structured, self-administered questionnaire. Twentyeightphysically active participants (78.6% male; 16–35years old) from a local gym were surveyed about their use oflegal supplements (creatine, caffeine) and illegal substances(anabolic-androgenic steroids, beta-2

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Casimiro-Lopes, Gustavo, and Gabriel Boaventura da Cunha. "Anabolic Androgenic Steroids Persistently Modify the User's Lipid Profile: a Case Report." Lecturas: Educación Física y Deportes 27, no. 290 (2022): 134–45. http://dx.doi.org/10.46642/efd.v27i290.2672.

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The aim of the study was to show a lasting modification of the lipid profile and atherogenic indices by the abuse of anabolic androgenic steroids (AAS) by a amateur bodybuilder. This study reports a case of a 27-year-old non-competitive bodybuilder with severe abnormalities in lipid profile and atherogenic indices. He used anabolic androgenic steroids and had no other risk factors for heart disease or associated risk factors. After some educational lectures, he decided to continue his training without using anabolic androgenic steroids or any illegal ergogenic drugs. Lipid profile and atheroge

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Ruan, Feng, Qiang Zheng, and Jinfu Wang. "Mechanisms of bone anabolism regulated by statins." Bioscience Reports 32, no. 6 (2012): 511–19. http://dx.doi.org/10.1042/bsr20110118.

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Osteoporosis is a common disease in the elderly population. The progress of this disease results in the reduction of bone mass and can increase the incidence of fractures. Drugs presently used clinically can block the aggravation of this disease. However, these drugs cannot increase the bone mass and may result in certain side effects. Statins, also known as HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, have been widely prescribed for CVD (cardiovascular disease) for decades. Nonetheless, several studies have demonstrated that statins exert bone anabolic effect and may be help

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Girotra, Monica, Mishaela R. Rubin, and John P. Bilezikian. "Anabolic skeletal therapy for osteoporosis." Arquivos Brasileiros de Endocrinologia & Metabologia 50, no. 4 (2006): 745–54. http://dx.doi.org/10.1590/s0004-27302006000400019.

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Antiresorptive agents for osteoporosis are a cornerstone of therapy, but anabolic drugs have recently widened our therapeutic options. By directly stimulating bone formation, anabolic agents reduce fracture incidence by improving bone qualities besides increasing bone mass. In this article, we review the role of anabolic treatment for osteoporosis. The only anabolic agent currently approved in the United States for osteoporosis, teriparatide [recombinant human parathyroid hormone(1-34)], has clearly emerged as a major approach to selected patients with osteoporosis. Teriparatide increases bone

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Ip, Eric J., Shadi Doroudgar, Bonnie Lau, and Mitchell J. Barnett. "Anabolic steroid users' misuse of non-traditional prescription drugs." Research in Social and Administrative Pharmacy 15, no. 8 (2019): 949–52. http://dx.doi.org/10.1016/j.sapharm.2018.07.003.

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Tauchen, Jan, Michal Jurášek, Lukáš Huml, and Silvie Rimpelová. "Medicinal Use of Testosterone and Related Steroids Revisited." Molecules 26, no. 4 (2021): 1032. http://dx.doi.org/10.3390/molecules26041032.

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Testosterone derivatives and related compounds (such as anabolic-androgenic steroids—AAS) are frequently misused by athletes (both professional and amateur) wishing to promote muscle development and strength or to cover AAS misuse. Even though these agents are vastly regarded as abusive material, they have important pharmacological activities that cannot be easily replaced by other drugs and have therapeutic potential in a range of conditions (e.g., wasting syndromes, severe burns, muscle and bone injuries, anemia, hereditary angioedema). Testosterone and related steroids have been in some cou

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Horn, Kate, Sophie Poore, and Arnold Fernandes. "P214 The use of anabolic steroids in males attending a sexual health clinic." Sexually Transmitted Infections 93, Suppl 1 (2017): A86.2—A86. http://dx.doi.org/10.1136/sextrans-2017-053232.256.

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IntroductionA 2013 study by Public Health England stated ‘Men who inject anabolic steroids (AS) and tanning drugs are at higher risk of HIV and viral hepatitis’. Injectors of AS are now the biggest client group at many needle and syringe programmes in the UK. The British Crime Survey on AS use among 16–59 year olds in England and Wales found in 2009/2010 0.7% had ever used and 0.2% had used in the last year. There have been no studies looking specifically at prevalence in sexual health clinic attendees and we wondered whether this might represent a different population.MethodsAll male attendee

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Semenov, V. V., V. A. Glumova, and V. V. Trusov. "Anabolic steroids in experimental and clinical medicine." Kazan medical journal 66, no. 1 (1985): 48–50. http://dx.doi.org/10.17816/kazmj60547.

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Drugs that affect metabolic processes in the body include anabolic steroid hormones, synthetic analogs of male sex hormones, devoid of sexual activity, but retaining a positive effect on growth, body weight, myotropic activity and nitrogen balance.

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Van der Merwe, PJ. "Drugs in sport — testing results from the South African Laboratory 1995 - 2002." South African Journal of Sports Medicine 16, no. 1 (2004): 29. http://dx.doi.org/10.17159/2413-3108/2004/v16i1a191.

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Objective. To summarise the results of the past 8 years obtained at the South African Doping Control Laboratory and to compare the results with international statistics. Method. Screening procedures were performed on 14 017 urine samples collected from competitors in 54 different sporting codes during the period 1995 - 2002. Samples were analysed using gas chromatography and gas chromatography/mass spectrometry for the presence of prohibited substances, which are listed by the International Olympic Committee (IOC). Results. The results obtained were compared with those of the IOC-accredited la

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Van der Merwe, PJ. "Drugs in sport — testing results from the South African Laboratory 1995 - 2002." South African Journal of Sports Medicine 16, no. 1 (2004): 29. http://dx.doi.org/10.17159/2078-516x/2004/v16i1a191.

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Objective. To summarise the results of the past 8 years obtained at the South African Doping Control Laboratory and to compare the results with international statistics. Method. Screening procedures were performed on 14 017 urine samples collected from competitors in 54 different sporting codes during the period 1995 - 2002. Samples were analysed using gas chromatography and gas chromatography/mass spectrometry for the presence of prohibited substances, which are listed by the International Olympic Committee (IOC). Results. The results obtained were compared with those of the IOC-accredited la

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Kicman, Andrew T., and D. B. Gower. "Anabolic steroids in sport: biochemical, clinical and analytical perspectives." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 40, no. 4 (2003): 321–56. http://dx.doi.org/10.1258/000456303766476977.

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International Olympic Committee accredited laboratories play a key role in upholding the principle of fair play and innate ability, as desired by the majority of sports competitors and spectators. Not only does doping damage the image of sport, but it can also be harmful to the individual. The great majority of samples test negative but, when an adverse finding is declared, the analytical data must be of a sufficiently high standard to withstand legal challenges by third parties. The most widely misused performance-enhancing drugs are the anabolic-androgenic steroids, commonly referred to as '

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Chyka, Peter A. "Health Risks of Selected Performance-Enhancing Drugs." Journal of Pharmacy Practice 16, no. 1 (2003): 37–44. http://dx.doi.org/10.1177/0897190002239631.

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This article reviews adverse effects of and the difficulty of attributing toxic effects to selected drugs and dietary supplements that purportedly enhance athletic performance. On surveys estimating the extent of performance-enhancing drug use, 5% of high school students indicated anabolic-adrenergic steroid use, and approximately 28% of collegiate athletes and 5.6% of middle and high school athletes admitted creatine use. Many adverse health effects from the abuse of androgenic-anabolic steroids and androstenedione (a prodrug) are exaggerations of excessive testosterone on hepatic, cardiovasc

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Schänzer, W. "Metabolism of anabolic androgenic steroids." Clinical Chemistry 42, no. 7 (1996): 1001–20. http://dx.doi.org/10.1093/clinchem/42.7.1001.

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Abstract Anabolic androgenic steroids (AAS) are misused to a high extent in sports by athletes to improve their physical performance. Sports federations consider the use of these drugs in sports as doping. The misuse of AAS is controlled by detection of the parent AAS (when excreted into urine) and (or) their metabolites in urine of athletes. I present a review of the metabolism of AAS. Testosterone is the principal androgenic steroid and its metabolism is compared with that of AAS. The review is divided into two parts: the general metabolism of AAS, which is separated into phase I and phase I

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Ebenhöh, Oliver, Josha Ebeling, Ronja Meyer, Fabian Pohlkotte, and Tim Nies. "Microbial Pathway Thermodynamics: Stoichiometric Models Unveil Anabolic and Catabolic Processes." Life 14, no. 2 (2024): 247. http://dx.doi.org/10.3390/life14020247.

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The biotechnological exploitation of microorganisms enables the use of metabolism for the production of economically valuable substances, such as drugs or food. It is, thus, unsurprising that the investigation of microbial metabolism and its regulation has been an active research field for many decades. As a result, several theories and techniques were developed that allow for the prediction of metabolic fluxes and yields as biotechnologically relevant output parameters. One important approach is to derive macrochemical equations that describe the overall metabolic conversion of an organism an

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Zalewa, Karolina, Joanna Olszak, Wojciech Kapłan, Dominika Orłowska, and Lidia Bartoszek. "Drugs and other substances aggravating acne vulgaris." Journal of Education, Health and Sport 70 (October 31, 2024): 55774. http://dx.doi.org/10.12775/jehs.2024.70.55774.

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Introduction and Purpose This review explores several factors exacerbating acne, including the supplementation of vitamins B6 and B12, the impact of red ginseng oil, dairy and whey product consumption, iodine association, anabolic-androgenic steroids, alcohol abuse, and the influence of progestin contraceptives. Material and methods This review is based on articles from the PubMed database, covering the years 2018-2023, using keywords: acne vulgaris, acne vulgaris aggravation, substances aggravating acne vulgaris. Results High doses of B6 and B12 have been reported to worsen acne, potentially

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Tkacheva, Olga N., Natalia V. Brailova, Ekaterina N. Dudinskaya, and Veronika A. Kuznesova. "Osteoporosis drug treatment after fracture." Osteoporosis and Bone Diseases 23, no. 4 (2021): 30–36. http://dx.doi.org/10.14341/osteo12694.

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The prevalence of osteoporosis, especially among the elderly, is increasing exponentially, leading to an increase in the number of fractures and disability. As a result, new requirements for anti-osteoporotic therapy appear, associated with its influence not only on the remodeling of healthy bone, but also on the acceleration of fracture consolidation. The article provides a brief overview of the effect of various anti-osteoporotic drugs on the healing of bone fractures. An assessment of the consolidating effect of antiresorptive drugs — bisphosphonates and denosumab, and anabolic drug — terip

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Ахмедов, М. Н., та А. А. Федоров. "Селективные модуляторы андрогенных рецепторов как предмет незаконного оборота сильнодействующих веществ." СОВРЕМЕННОЕ ПРАВО, № 7-8 (19 серпня 2019): 138–42. https://doi.org/10.25799/ni.2019.35.87.024.

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Анаболические стероиды уже длительное время находятся в запрещенном списке WADA и списке сильнодействующих веществ в Российской Федерации. Относительно недавно появилась новая группа препаратов, обладающая теми же эффектами, что и анаболические стероиды, но с гораздо менее ярко выраженным негативным воздействием. И если включение этой группы препаратов в список WADA выглядит оправданным, то присутствие их в списке сильнодействующих веществ вызывает определенные вопросы. Anabolic steroids have long been on the WADA ban list and the list of potent substances in the Russian Federation. Relatively

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Zahra, Naseem, Sabahat Mahnoor, Abdul Ahad, and Rida Ishfaq. "Preamble of Steroids Types and Presence of Androgenic Anabolic Steroids (AAS) in Humans and Animals." Lahore Garrison University Journal of Life Sciences 5, no. 02 (2021): 110–22. http://dx.doi.org/10.54692/lgujls.2021.0502153.

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ABSTRACT: Steroids are the hormones; the main source of which are Adrenal glands and Gonads. Human body produced them naturally in a balanced quantity.They have mainly two types i.e. corticosteroids and anabolic-androgenic steroids (or in short form “anabolic”). Now-a-days these are artificially synthesized as drugs which are given to humans and animals. Anabolic steroids are naturally produced in body 4.0–9.0 mg per day. They are also used artificially to treat testosterone level in human body while athletes are using them to build their muscles. Athletes misuse this drug 10 to 1000 times mor

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DuRant, Robert H., Vaughn I. Rickert, Carolyn Seymore Ashworth, Cheryl Newman, and Gregory Slavens. "Use of Multiple Drugs among Adolescents Who Use Anabolic Steroids." New England Journal of Medicine 328, no. 13 (1993): 922–26. http://dx.doi.org/10.1056/nejm199304013281304.

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Bahrke, Michael S., Charles E. Yesalis, and Kirk J. Brower. "Anabolic-Androgenic Steroid Abuse and Performance-Enhancing Drugs Among Adolescents." Child and Adolescent Psychiatric Clinics of North America 7, no. 4 (1998): 821–38. http://dx.doi.org/10.1016/s1056-4993(18)30214-1.

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Thanage, Ravi, Sanjay Chandnani, Vinay Zanwar, et al. "Unusual Case of Simultaneous Acute Hepatitis and Acute Pancreatitis in a Bodybuilder." Journal of Gastroenterology, Pancreatology & Liver Disorders 7, no. 1 (2019): 1–3. http://dx.doi.org/10.15226/2374-815x/7/1/001137.

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The use of anabolic steroids is widespread, particularly among bodybuilders. Most athletes have only a crude pharmacological knowledge regarding these drugs and warnings of steroid misuse are neglected. The illicit use of Androgenic Anabolic Steroids (AAS) to obtain an athletic, healthy looking body can lead to serious and often irreversible organ damage [1]. Anabolic steroids with 17 alpha carbon substitutions have been associated with a cholestatic injury with little hepatocellular injury. In the case of hepatoxicity and severe cholestasis the prompt withdrawal of the steroid and the adminis

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Goldberg, Linn, Robert Bents, Eric Bosworth, Louis Trevisan, and Diane L. Elliot. "Anabolic Steroid Education and Adolescents: Do Scare Tactics Work?" Pediatrics 87, no. 3 (1991): 283–86. http://dx.doi.org/10.1542/peds.87.3.283.

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The opinions (level of agreement) of high school varsity football players with regard to reported effects of anabolic steroids were assessed before and after two different education interventions. Lectures and handouts of a balanced education program (potential risks and benefits) were compared with a risks-only (negative or "scare tactics") presentation, in a controlled manner. Those receiving the balanced review significantly increased their agreement with 5 of 10 targeted adverse effects, while no change occurred for any risks among those taught by the negative intervention. A teaching mode

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Stoll, Anna, Michele Iannone, Giuseppina De Gregorio, et al. "Influence of Pain Killers on the Urinary Anabolic Steroid Profile." Journal of Analytical Toxicology 44, no. 8 (2020): 871–79. http://dx.doi.org/10.1093/jat/bkaa049.

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Abstract Anabolic androgenic steroids (AAS) are prohibited as performance-enhancing drugs in sports. Among them, testosterone and its precursors are often referred to as “pseudoendogenous” AAS, that is, endogenous steroids that are prohibited when administered exogenously. To detect their misuse, among other methods, the World Anti-Doping Agency-accredited laboratories monitor the steroid profile (concentrations and concentration ratios of endogenous steroids, precursors and metabolites) in urine samples collected from athletes in and out of competition. Alterations in steroid profile markers

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Heydari, Aghigh, Atefeh Asadmobini, and Feridoun Sabzi. "Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series." Oman Medical Journal 35, no. 5 (2020): e179-e179. http://dx.doi.org/10.5001/omj.2020.120.

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The use of anabolic steroids in supraphysiologic doses has grown in the last decade as doping drugs in athletes. The high dose of anabolic-androgenic steroids (AAS) causes cardiomyopathy, hypertension, thrombosis, myocardial infarction (MI), weakness of connective tissue, and its sequelae such as tendon injury and aortic dissection. Dissection of the ascending aorta is an uncommon injury that has been recognized with increasing frequency in bodybuilders in recent years. It has been proposed that such cases commonly accompany the weakening of connective tissue and must be actively evaluated in

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Anshel, Mark H., and Kenneth G. Russell. "Examining Athletes' Attitudes toward Using Anabolic Steroids and Their Knowledge of the Possible Effects." Journal of Drug Education 27, no. 2 (1997): 121–45. http://dx.doi.org/10.2190/714t-aum5-neul-8y0q.

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One goal of contemporary sports leaders is to eradicate the use of banned drugs in competitive sport. A common approach to achieving this outcome is to provide athletes with adequate education about the effects of drug use. Ostensibly, educational programs about the deleterious effects of using anabolic steroids are thought to discourage their intake. Thus, the purpose of this study was to examine the relationships between the athletes' knowledge about the long-term effects of anabolic steroids and their attitudes toward this type of drug. Multiple regression analyses indicated relatively low

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Coliță, Daniela, Cezar-Ivan Coliță, Dirk M. Hermann, et al. "Therapeutic Use and Chronic Abuse of CNS Stimulants and Anabolic Drugs." Current Issues in Molecular Biology 44, no. 10 (2022): 4902–20. http://dx.doi.org/10.3390/cimb44100333.

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The available evidence suggests that affective disorders, such as depression and anxiety, increase risk for accelerated cognitive decline and late-life dementia in aging individuals. Behavioral neuropsychology studies also showed that cognitive decline is a central feature of aging impacting the quality of life. Motor deficits are common after traumatic brain injuries and stroke, affect subjective well-being, and are linked with reduced quality of life. Currently, restorative therapies that target the brain directly to restore cognitive and motor tasks in aging and disease are available. Howev

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Lyublinskaya, Irina E. "How Fair Is the Drug Test?" Mathematics Teacher 98, no. 8 (2005): 536–43. http://dx.doi.org/10.5951/mt.98.8.0536.

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The non–medical use of anabolic/androgenic steroids among adolescents and young adults is of growing concern. As many as half a million Americans under age 18 may be abusing these drugs to improve athletic performance, appearance and self–image.

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M. Siddiqui, Atia-tul-Wahab, B. M. Kudaibergenova, Zh.A. Abilov, and M.I. Choudhary. "Biotransformation of anabolic drug Dianabol with Rizhopus oryzae." International Journal of Biology and Chemistry 17, no. 1 (2024): 108–11. http://dx.doi.org/10.26577/ijbch2024v17i1-a12.

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Microbial biotransformation technique is an excellent approach for the synthesis of stereo-, enantio-, chemo-, and regio-selective/specific analogues of existing steroidal and non-steroidal drugs by using bacteria, fungi, algae, actinomycetes, yeast, and plants and animals cell cultures. This technique is effectively used to synthesize compounds whose structures resemble to the substrates (parent drugs) without using protecting/deprotecting steps. In the current study, an anabolic-androgenic steroid (AAS) based drug, methandienone (dianabol) (1) was incubated with the filamentous fungi Rhizopu

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Currow, David, Matthew Maddocks, David Cella, and Maurizio Muscaritoli. "Efficacy of Anamorelin, a Novel Non-Peptide Ghrelin Analogue, in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) and Cachexia—Review and Expert Opinion." International Journal of Molecular Sciences 19, no. 11 (2018): 3471. http://dx.doi.org/10.3390/ijms19113471.

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Cancer cachexia is a multilayered syndrome consisting of the interaction between tumor cells and the host, at times modulated by the pharmacologic treatments used for tumor control. Key cellular and soluble mediators, activated because of this interaction, induce metabolic and nutritional alterations. This results in mass and functional changes systemically, and can lead to increased morbidity and reduced length and quality of life. For most solid malignancies, a cure remains an unrealistic goal, and targeting the key mediators is ineffective because of their heterogeneity/redundancy. The most

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Durgia, Harsh, Rajan Palui, Jayaprakash Sahoo, Sadishkumar Kamalanathan, and Dukhabandhu Naik. "Role of Anabolic Anti-Osteoporosis Therapy in Diabetes Subjects." Indian Journal of Endocrinology and Metabolism 29, no. 1 (2025): 32–38. https://doi.org/10.4103/ijem.ijem_81_24.

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Abstract Diabetes mellitus (DM) is a metabolic disorder that leads to the destruction of various tissues including bones. The pathogenesis of osteoporosis (OP) varies in DM due to many specific factors. DM increases the risk of fracture as well as post-fracture mortality. It is because of this fact that OP treatment should not be neglected in patients with DM. OP therapy comprises anabolic as well as anti-resorptive agents. Primary OP as observed in post-menopausal women is associated with high bone turnover, whereas OP in DM is a disease of low bone turnover. Therefore, anabolic agents seem t

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Johnson, Mimi D., M. Susan Jay, Brad Shoup, and Vaughn I. Rickert. "Anabolic Steroid Use by Male Adolescents." Pediatrics 83, no. 6 (1989): 921–24. http://dx.doi.org/10.1542/peds.83.6.921.

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Anabolic steroids have recently been used by professional and college athletes to improve athletic ability by increasing muscle size and strength. A study was done to determine the extent of steroid use and knowledge about these drugs in a population of high school male adolescents in a southern state. A self-report questionnaire, which allowed multiple answers for each question, was administered to 853 male students in six high schools. Results indicated that an average of 11% had used or were using anabolic steroids. The following were assessed: the reasons for steroid use, the sources from

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Kuril, Akhilesh Kumar, Krishna Moorthy Manchuri, and Swapnil Prakash Anand. "Emerging Protein and Peptide Therapeutics for Osteoporosis: Advances in Anabolic and Catabolic Treatments." Journal of Pharmaceutical Research International 36, no. 11 (2024): 85–102. http://dx.doi.org/10.9734/jpri/2024/v36i117603.

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Osteoporosis is a prevalent skeletal disorder characterized by reduced bone density and increased fracture risk, primarily affecting the elderly population. The pathophysiology of osteoporosis involves an imbalance between bone resorption and bone formation, with catabolic processes (bone breakdown) counteracting anabolic processes (bone formation). Treatment strategies for osteoporosis are categorized into anabolic and catabolic approaches, each targeting different aspects of bone metabolism. Catabolic treatments focus on inhibiting bone resorption. peptides, such as Calcitonin Salmon and mon

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