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Książki na temat „Antagonistic potential”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Sirinathsinghji, Dalip J. S., and Ray G. Hill, eds. NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5.

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2

Rayat, Harnak Singh. The synthesis of potential steroid receptor antagonists. typescript, 1995.

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3

1943-, Greenwald Robert A., Golub Lorne M, and New York Academy of Sciences., eds. Inhibition of matrix metalloproteinases: Therapeutic potential. New York Academy of Sciences, 1994.

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4

1930-, Smith H. J., and Simons Claire, eds. Proteinase and peptidase inhibition: Recent potential targets for drug development. Taylor & Francis, 2002.

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5

Divya, Vohora, ed. The third histamine receptor: Selective ligands as potential therapeutic agents in CNS disorders. CRC Press, 2009.

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6

Athanasius, Anagostou, Dainiak Nicholas, Najman Albert, and International Conference on Negative Regulators of Hematopoiesis, (2nd : 1990 : Providence, R.I.), eds. Negative regulators of hematopoiesis: Studies of their nature, action, and potential role in cancer therapy. New York Academy of Sciences, 1991.

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7

Hill, Ray G. NMDA Antagonists As Potential Analgesic Drugs. Birkhauser Verlag, 2012.

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8

Sirinathsinghji, Dalip J. S. NMDA Antagonists as Potential Analgesic Drugs. Springer, 2012.

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9

Woods, Matthew. Insomnia Treatments: Therapeutic Potential of Orexin Antagonist. American Medical Publishers, 2021.

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10

Kanduč, M., A. Schlaich, E. Schneck, and R. R. Netz. Interactions between biological membranes: theoretical concepts. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198789352.003.0012.

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In this chapter we review the various types of generic (non-specific) forces acting between lipid membranes in an aqueous environment and discuss the underlying mechanisms, with particular focus on the competing roles of enthalpic and entropic contributions. The interaction free energy (or interaction potential) is typically the result of a subtle interplay of several, often antagonistic contributions with comparable magnitude. First, we will briefly introduce the underlying physics of various kinds of surface–surface interactions, starting with theories of van der Waals and undulation interac

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11

Dalip J.S. Sirinathsinghji (Editor) and Ray G. Hill (Editor), eds. NMDA antagonists as potential analgesic drugs (Progress in Inflammation Research). Birkhäuser Basel, 2002.

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12

Steiner, Michel Alexander. Insomnia and beyond - Exploring the therapeutic potential of orexin receptor antagonists. Edited by Christopher J. Winrow. Frontiers SA Media, 2014. http://dx.doi.org/10.3389/978-2-88919-330-1.

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13

Singha, Prasad, Dharnendra Reang, and Mayanglabambam Ranjana Devi. In-Vitro Evaluation of Antagonistic Potentials of Some Yeast Isolates Against Different Plant Pathogenic Fungi. GRIN Verlag GmbH, 2017.

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14

Henter, Ioline D., and Rodrigo Machado-Vieira. Novel therapeutic targets for bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0030.

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The long-term course of bipolar disorder (BD) comprises recurrent depressive episodes and persistent residual symptoms for which standard therapeutic options are scarce and often ineffective. Glutamate is the major excitatory neurotransmitter in the central nervous system, and glutamate and its cognate receptors have consistently been implicated in the pathophysiology of mood disorders and in the development of novel therapeutics for these disorders. Since the rapid and robust antidepressant effects of the N-methyl-D-aspartate (NMDA) antagonist ketamine were first observed in 2000, other NMDA

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15

Hummer, Hans. Visions of Kinship in Medieval Europe. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198797609.001.0001.

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What meaning did human kinship possess in a world regulated by biblical time, committed to the primacy of spiritual relationships, and bound by the sinews of divine love? In the process of exploring that question, this book offers a searching re-examination of kinship in Europe between late Roman times and the high Middle Ages, the period bridging Europe’s primitive past and its modern present. It critiques the modernist and Western bio-genealogical and functionalist assumptions that have shaped kinship studies since their inception in the nineteenth century, when biblical time collapsed and k

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16

Simons, Claire, and H. John Smith. Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development. Taylor & Francis Group, 2002.

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17

Simons, Claire, and H. John Smith. Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development. Taylor & Francis Group, 2002.

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18

Spindler, Edeltraut. Einfluss des physiologischen Ca2+-Antagonisten Mg2+ und des pharmakologischen Ca2+-Antagonisten Nifedipin auf die potential- bzw. rezeptorgesteuerte transsarkolemmale Ca2+-Aufnahme in glatte Gefässmuskelzellen von Schweinekoronararterien. 2000.

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19

Design of caspase inhibitors as potential clinical agents. Taylor & Francis, 2009.

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20

Simons, Claire, H. John Smith, and Steven D. Linton. Design of Caspase Inhibitors As Potential Clinical Agents. Taylor & Francis Group, 2008.

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21

Kiel, Universität, ed. Die Potential-Abhängigkeit der Bindung und Wirkung des Dihydropyridin-Kalzium-Antagonisten Isradipin an der Taenia coli des Meerschweinchens. 1990.

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22

Rao, Shilpa, and Jerrold Lerman. Postoperative Nausea and Vomiting in Patients with Prolonged QTc. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0070.

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A panoply of pharmacological and nonpharmacological strategies are currently employed to attenuate the risk of postoperative nausea and vomiting (PONV) in children, including 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists. 5-HT3 receptor antagonists can prolong the QT interval, which can be a precursor of torsades de pointes (TdP), particularly in children with congenital or acquired prolonged QT interval. This chapter summarizes the causes of prolonged QT interval, the potential interactions of prolonged QT interval with antiemetics and anesthetics, and strategies to prevent PONV.

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23

Kurachi, Y., M. Mishina, and M. Endo. Pharmacology of Ionic Channel Function: Activators and Inhibitors. Springer London, Limited, 2012.

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24

Kurachi, Y., Masayoshi Mishina, and M. Endo. Pharmacology of Ionic Channel Function: Activators and Inhibitors. Springer Berlin / Heidelberg, 2012.

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25

(Editor), M. Endo, Y. Kurachi (Editor), and M. Mishina (Editor), eds. Pharmacology of Ionic Channel Function: Activators and Inhibitors (Handbook of Experimental Pharmacology). Springer, 2000.

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26

Simons, Claire, and H. John Smith. Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development. Taylor & Francis Group, 2002.

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27

Simons, Claire, and H. John Smith. Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development. Taylor & Francis Group, 2002.

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28

Simons, Claire, and H. John Smith. Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development. Taylor & Francis Group, 2002.

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29

(Editor), H. John Smith, and Claire Simons (Editor), eds. Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development. CRC, 2002.

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30

Numerof, R., Charles A. Dinarello, and Khusru Asadullah. Cytokines As Potential Therapeutic Targets for Inflammatory Skin Diseases. Springer Berlin / Heidelberg, 2014.

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31

Linton, Steven D., and Tom O'Brien. Design of Caspase Inhibitors As Potential Clinical Agents. Taylor & Francis Group, 2019.

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32

Linton, Steven D., and Tom O'Brien. Design of Caspase Inhibitors As Potential Clinical Agents. Taylor & Francis Group, 2008.

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33

Linton, Steven D., and Tom O'Brien. Design of Caspase Inhibitors As Potential Clinical Agents. Taylor & Francis Group, 2008.

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34

Vohora, Divya. Third Histamine Receptor: Selective Ligands As Potential Therapeutic Agents in CNS Disorders. Taylor & Francis Group, 2008.

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35

Vohora, Divya. Third Histamine Receptor: Selective Ligands As Potential Therapeutic Agents in CNS Disorders. Taylor & Francis Group, 2008.

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36

Vohora, Divya. Third Histamine Receptor: Selective Ligands As Potential Therapeutic Agents in CNS Disorders. Taylor & Francis Group, 2008.

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37

Vohora, Divya. Third Histamine Receptor: Selective Ligands As Potential Therapeutic Agents in Cns Disorders. Taylor & Francis Group, 2008.

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38

Vohora, Divya. Third Histamine Receptor: Selective Ligands As Potential Therapeutic Agents in CNS Disorders. Taylor & Francis Group, 2008.

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39

The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders. CRC, 2008.

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40

Design of Caspase Inhibitors as Potential Clinical Agents (Enzyme Inhibitors). CRC, 2008.

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41

Negative regulators of hematopoiesis: Studies on their nature, action, and potential role in cancer therapy. New York Academy of Sciences, 1991.

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42

Najman, Albert, Athanasius Anagnostou, and Nicholas Dainiak. Negative regulators of hematopoiesis : Studies on their nature, action, and potential role in cancer therapy. New York Academy of Sciences, 1991.

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43

(Editor), Robert A. Greenwald, New York Academy of Sciences (Corporate Author), and Lorne M. Golub (Editor), eds. Inhibition of Matrix Metalloproteinases: Therapeutic Potential (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1994.

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44

Lameire, Norbert. Prevention of acute kidney injury. Edited by Norbert Lameire. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0226_update_001.

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This chapter summarizes the pharmacological interventions that can be used in the prevention of acute kidney injury (AKI). These following interventions are discussed: the use and selection of vasopressors; the administration of loop diuretics and mannitol; vasodilating drugs including dopamine, atrial natriuretic peptide, nesiritide, fenoldopam, and adenosine antagonists. The role of N-acetylcysteine in the prevention of contrast-induced AKI and cardiac surgery is discussed. The chapter concludes with a summary of the potential role of insulin-like growth factor and erythropoietin in the prev

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45

(Editor), Robert A. Greenwald, New York Academy of Sciences (Corporate Author), and Lorne M. Golub (Editor), eds. Inhibition of Matrix Metalloproteinases: Therapeutic Potential (Annals of the New York Academy of Sciences, Vol 732). New York Academy of Sciences, 1994.

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46

Anagnostou, Athanasius, and Nicholas Dainiak. Negative Regulators of Hematopoiesis: Studies on Their Nature, Action, and Potential Role in Cancer Therapy (Annals of the New York Academy of Scien). New York Academy of Sciences, 1991.

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47

Scheipers, Sibylle. Clausewitz and the Eighteenth-Century Context of Partisan Warfare. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198799047.003.0002.

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Clausewitz was an ardent analyst of partisan warfare. In 1810 and 1811, he lectured at the Berlin Kriegsschule, the war academy, on the subject of small wars. Clausewitz’s lectures focused on the tactical nature of small wars. However, the eighteenth-century context was by no means irrelevant for Clausewitz’s further intellectual development. On the contrary, he extrapolated from his analysis of the tactical nature of small wars their strategic potential, as well as their exemplary nature for the study of war as such. The partisan, in Clausewitz’s eyes, possessed exemplary qualities in that he

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48

Nutt, David J., and Liam J. Nestor. The opioid system and addiction. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198797746.003.0010.

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The opioid system of the brain is the major target for opiate drugs such as morphine and heroin, and has been implicated in processes such as pain, stress and reward. Many of these effects take place at the mu opioid receptor (mOR), which is distributed throughout the brain. Significantly, genetic polymorphisms at the mOR may confer a greater dopamine response to the reinforcing effects of alcohol, and it has been suggested that addiction per se may be associated with alterations to the opioid system. There is evidence for the potential efficacy of mOR antagonists (e.g. naltrexone) in reducing

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49

Ren, Ke, and Ronald Dubner. The first crystal structure of an ionotropic glutamate receptor ligand-binding core. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0032.

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The known functional ionotropic glutamate receptors (iGluRs) are composed of three major subtypes: AMPA, NMDA, and kainate. In 1998, in the landmark paper discussed in this chapter, Armstrong et al. provided the first crystal structure of an iGluR-subunit ligand-binding core, the S1S2 region of the rat GluA2 ‘flop’ isoform. They solved its structure with X-ray crystallography from selenomethonine crystals. They also identified residues involved in kainate binding, analysed allosteric sites that regulate affinity and specificity of the agonist, and mapped potential subunit–subunit interaction s

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50

Adler, Adam C., and Mehernoor Watcha. Postoperative Nausea and Vomiting in Patients with Prolonged QTc. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0067.

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Postoperative nausea and vomiting (PONV) is a very common complication after a general anesthetic. In some cases the feeling of nausea has been accredited to being worse than the actual pain. There are a number of medications that can be utilized to combat PONV. Of note, some of these agents can lead to cardiac arrhythmias. It is imperative to know which drugs may predispose patients to arrhythmias such as prolonged QT intervals as well as how to prevent or treat PONV in the patient with prolonged QT interval. This chapter discusses the basics of cardiac electrophysiology regarding the QT inte

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