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Artykuły w czasopismach na temat „Anti-coagulation therapy”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

SOEJIMA, Hirofumi, Koichi KAIKITA, Seiji HOKIMOTO, Kenichi TSUJITA, and Hisao OGAWA. "Anti-coagulation and anti-platelet therapy for heart disease." Japanese Journal of Thrombosis and Hemostasis 23, no. 1 (2012): 25–32. http://dx.doi.org/10.2491/jjsth.23.25.

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Miyazaki, Yusuke, Kazuhiro Sase, Koji Hasegawa, and Tatsuya Morimoto. "VTE and anti-coagulation therapy in cancer patients." European Heart Journal - Cardiovascular Pharmacotherapy 5, no. 4 (2019): 189–91. http://dx.doi.org/10.1093/ehjcvp/pvz027.

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Eguchi, Y. "EFFICACY OF ANTI-COAGULATION AND ANTI-INFLAMATORY THERAPY FOR SEVERE SEPSIS." Journal of Thrombosis and Haemostasis 5 (July 2007): P—M—223—P—M—223. http://dx.doi.org/10.1111/j.1538-7836.2007.tb01158.x.

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Nasreen, Noor Suhail Ahmed Almani Shafaq Nazia Muhammad Iqbal Shah* Aatir H. Rajput Muhammad Muneeb Syed Jehangir and Shahrukh Shaikh. "CROSS-SECTIONAL ANALYSIS OF DANGERS INHERENT WITH PRE AND POST PARTUM USE OF ANTICOAGULATION THERAPY." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1422–25. https://doi.org/10.5281/zenodo.817584.

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Background:The rate of thrombotic mal-events is three-fold to five-fold greater during pre-partum and post-partum phases than at any other time in a women’s life and thus many women receive anticoagulant therapy during pregnancy and puerperium, despite evidence suggesting that this therapy may pose grave danger to the well-being of the fetus and the mother. Objective: This research hopes to highlight the dangers inherent (to the mother and fetus) with the pre-partum and post-partum use of anti-coagulation therapy. Methodology This retrospective analysis is built upon the primary data, availabl

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Ikura, Yoshihiro. "Changing common sense: Anti-platelet/coagulation therapy against cirrhosis." World Journal of Hepatology 7, no. 13 (2015): 1730. http://dx.doi.org/10.4254/wjh.v7.i13.1730.

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Harky, Amer, Perry Maskell, and Mika Burgess. "Anti-platelet and anti-coagulant therapy in peripheral arterial disease prior to surgical intervention." Vascular 27, no. 3 (2018): 299–311. http://dx.doi.org/10.1177/1708538118818622.

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Objective Peripheral artery disease is a major clinical co-morbidity that can significantly affect quality of life, especially in the presence of diabetes mellitus and older age. The focus of this literature review is on medical management, through anti-platelet and anti-coagulation, of peripheral artery disease prior to undergoing surgical or endovascular management. Method Extensive electronic literature search performed in four major databases (PubMed, SCOPUD, Embase and Ovid) to identify the published randomized and non-randomized studies that compared and discussed the management of perip

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Katargina, L. A., and E. N. Demchenko. "New opportunities in management of patients with retinopathy prematurity (literature review and analysis of own data)." Russian Ophthalmological Journal 13, no. 4 (2020): 70–74. http://dx.doi.org/10.21516/2072-0076-2020-13-4-70-74.

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Insufficient effectiveness of laser coagulation of the avascular retinal areas in retinopathy of prematurity (ROP) plus-disease in zone I and aggressive posterior retinopathy of prematurity (APROP) requires new treatment approaches, based on the regulation of retinal angiogenesis and anti-VEGF drugs use. The BEAT-RAP study, which was the first major randomized study of anti-VEGF therapy in ROP, revealed a higher effectiveness of bevacizumab compared to retinal laser coagulation in stage 3 plus-disease of zone I. A prospective randomized trial, RAINBOW, demonstrated the effectiveness of ranibiz

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Valaitienė, Julija. "IMPACT OF CONTACT SYSTEM ON CARDIOVASCULAR DISEASES." Health Sciences 34, no. 3 (2024): 164–68. http://dx.doi.org/10.35988/sm-hs.2024.126.

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Contact and intrinsic coagulation pathway components are involved in pathological thrombus formation. In addition to coagulation, contact system activation is involved in anti/profibrinolytic and inflammatory processes that can contribute to the atherosclerotic and thrombotic environment, leading to cardiovascular diseases. This literature review concerns the role of the contact system on cardiovascular diseases and accentuates the potential of coagulation factors FXII (FXII) and FXI (FXI) as targets for antithrombotic therapy.

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Wallace, John L. "Novel Targets for Anti-Inflammatory Therapy in Inflammatory Bowel Disease." Canadian Journal of Gastroenterology 8, no. 6 (1994): 373–78. http://dx.doi.org/10.1155/1994/765272.

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Until the cause(s) of inflammatory bowel disease are identified, improvements in therapy will likely come from improved anti-inflammatory therapy or improved drug delivery systems. There are many potential targets for anti-inflammatory therapy, including the synthesis of specific inflammatory mediators. This review focuses on the potential for developing therapy aimed at three targets: nerves and neuropeptides; coagulation and thrombosis; and adhesion molecules. In each case, evidence is presented from clinical and/or experimental studies that supports the hypothesis that these are rational ta

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Lim, Cheryl XQ, Priscella Shirley Chia, and Eng Soo Yap. "Asian Experience of Treating Venous Thromboembolism in Patients with Acute Leukaemia." Blood 134, Supplement_1 (2019): 1161. http://dx.doi.org/10.1182/blood-2019-130041.

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Background Cancer is a known risk factor for venous thromboembolic (VTE) events. Thromboembolism occurs frequently during acute leukemia and the reported incidence of VTE in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are 5% and 6% respectively. However, majority of studies are conducted in Western population and data on VTE events in Asians with acute leukemia is scarce with only 1 published study. Objectives We aim to retrospectively evaluate the risk of thrombosis in Asian patients with acute leukemia and share our experience treating them. Patients and Methods This

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11

Göbel, Sebastian, Jürgen Prochaska, Lisa Eggebrecht, et al. "Management of Oral Anti-Coagulation in Patients with Heart Failure—Insights from the ThrombEVAL Study." Thrombosis and Haemostasis 118, no. 11 (2018): 1930–39. http://dx.doi.org/10.1055/s-0038-1673380.

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AbstractPatients with heart failure (HF) are frequently anti-coagulated with vitamin K-antagonists (VKAs). The use of long-acting VKA may be preferable for HF patients due to higher stability of plasma concentrations. However, evidence on phenprocoumon-based oral anti-coagulation (OAC) therapy in HF is scarce. The aim of this study was to assess the impact of the presence of HF on quality of phenprocoumon-based OAC and the subsequent clinical outcome. Quality of OAC therapy and the incidence of adverse events were analysed in a cohort of regular care (n = 2,011) from the multi-centre thrombEVA

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12

Hassan, Taha F., Merry Mathew, Sai Pranathi Bingi, et al. "786 Decreased Coagulation Activity in Burn Shock Patients Administered Albumin Supplementation." Journal of Burn Care & Research 45, Supplement_1 (2024): 251. http://dx.doi.org/10.1093/jbcr/irae036.326.

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Abstract Introduction Burn shock is a systemic inflammatory response and potentially fatal complication of severe burns. Traditional management of burn shock utilizes fluid resuscitation, which involves the administration of crystalloid or colloid solutions. Commonly used colloid solutions include albumin and plasma. Albumin has recently gained traction as a component of this fluid resuscitation; however, it has demonstrated anti-coagulant activity. It is imperative that we study potential coagulation changes as burn patients are already at risk for various other complications. Methods This st

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13

Akhzari, Amir, Vladimir Sabayev, and Amreen Dinani. "EFFECT OF ANTI-PLATELET/ANTI-COAGULATION (AC) THERAPY IN PATIENTS WITH GIB REQUIRING ICU ADMISSION." Chest 136, no. 4 (2009): 26S. http://dx.doi.org/10.1378/chest.136.4_meetingabstracts.26s-a.

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Gamidov, A. A., Z. V. Surnina, I. V. Andreeva та I. A. Velieva. "Сombined (anti-VEGF and laser) treatment for operated secondary refractory neovascular glaucoma". POINT OF VIEW. EAST – WEST, № 4 (2 листопада 2021): 24–26. http://dx.doi.org/10.25276/2410-1257-2021-4-24-26.

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Purpose. To develop an optimal algorithm for the management of patients with operated neovascular uncompensated glaucoma. Material and methods. 2 patients with operated secondary neovascular glaucoma of stage III-c. In the combined sequential therapy, the anti-VEGF medication Ranibizumab (0.5 mg) was used, laser coagulation of residual newly formed vessels, laser reconstruction in the surgical area, contact transcleral cyclolazercoagulation, and laser coagulation of the peripheral parts of the retina were performed. Results. The combined sequential treatment, combined with the appointment of a

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15

Kodama, Rich, Amardeep Kalsi, Angelica Singh, et al. "Outcomes in COVID-19 Patients on Treatment Dose Anti-Coagulation Compared to Prophylactic Dose Anti-Coagulation." Blood 136, Supplement 1 (2020): 40–41. http://dx.doi.org/10.1182/blood-2020-142552.

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Introduction The outcomes related to different anticoagulation doses in Coronavirus disease 2019 (COVID-19) patients are not well established. COVID-19 is associated with increased thrombotic events and early coagulopathy as reported by a large New York City health system. Initial studies on patients in Wuhan, China showed anticoagulant therapy mainly with low molecular weight heparin was reported to be associated with better prognosis in severe COVID-19 patients meeting sepsis-induced coagulopathy criteria or with markedly elevated D-dimer. These studies fueled the need for anticoagulation pr

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Stratton, Tyler W., Guangheng Zhu, Yiming Wang та ін. "Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone". Blood 132, Supplement 1 (2018): 1246. http://dx.doi.org/10.1182/blood-2018-99-119964.

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Abstract Integrin αIIbβ3 plays key roles in thrombosis and hemostasis primarily through mediating platelet adhesion and aggregation. We recently reported that the active site of thiol-isomerase enzymes, CXXC motif, is expressed twice within the plexin-semaphorin-integrin (PSI) domain across all integrins and species, and the PSI domain of β3 integrin possesses endogenous thiol-isomerase activity, which may be a novel target for anti-thrombotic therapy (Blood, 2017). We developed four mouse anti-mouse β3 integrin PSI domain monoclonal antibodies (mAbs). These mAbs cross-react with β3 PSI domain

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Aamer, Nasrullah, Muhammad Nouman, Shahid Hussain Memon, Zaheer Hussain Memon, Shazia Ahmed, and Hira Saeed. "Prevalence of Ischemic Versus Hemorrhagic Stroke in Patients Taking Anti-Coagulation Therapy." Journal of Islamabad Medical & Dental College 13, no. 2 (2024): 289–94. http://dx.doi.org/10.35787/jimdc.v13i2.1224.

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OBJECTIVE: To evaluate the prevalence of ischemic versus hemorrhagic stroke in patients taking anti-coagulation therapy. PATIENTS AND METHODS: This cross-sectional prospective study was conducted at medicine Departments of Peoples University of Medical & Health Sciences (PUMHS), for a period of 18 months from September 2021 to January 2023. All the patients taking anti-thrombotic therapy (warfarin, rivaroxaban, dabigatran, or apixaban) were included in this study and their baseline and clinical data were collected. Statistical package for the social sciences version (SPSS v. 26) was used f

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18

Landis, Clive. "Pharmacologic Strategies for Combating the Inflammatory Response." Journal of ExtraCorporeal Technology 39, no. 4 (2007): 291–95. http://dx.doi.org/10.1051/ject/200739291.

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The “systemic inflammatory response” is a multifaceted defensive reaction of the body to surgical trauma and cardiopulmonary bypass (CPB), characterized by systemic activation of fibrinolysis, coagulation, complement, immune cells, platelets, and oxidative pathways, all overlaid onto localized trauma to the grafted vessel or vascular beds susceptible to ischemia/reperfusion. There is going to be no single magic bullet to diminish such a broad host defense response to surgery. The best chance lies with combinatorial—or promiscuous—pharmacotherapy. Combinations of anti-fibrinolytics, anti-coagul

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Brinza, Melen, Valentina Uscatescu, Mihai Hemcinschi, Elisabeta Chiriac, Georgiana Gherghe, and Daniel Coriu. "Challenges in prophylactic therapy with Emicizumab in patients with hemophilia A: Focus on monitoring tests." Revista Romana de Medicina de Laborator 32, no. 1 (2024): 93–100. http://dx.doi.org/10.2478/rrlm-2024-0003.

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Abstract This study presents a transversal investigation that we performed at Fundeni hospital (Bucharest, Romania) into the therapeutic benefits and efficacy of Emicizumab, a non-factor therapy, in the context of hemophilia A. Ten patients diagnosed with hemophilia A were closely monitored using clinical and laboratory resources during Emicizumab treatment, with an average of 12.8 months. Among these patients, six exhibited anti-factor VIII inhibitors, changing the medical strategy and adding complexity to their clinical profiles. A comprehensive approach was adopted to assess the coagulation

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Silva, Vanessa M., Maurício Scanavacca, Francisco Darrieux, Cyrillo Cavalheiro, and Celia C. Strunz. "Routine Coagulation Tests in Patients With Nonvalvular Atrial Fibrillation Under Dabigatran and Rivaroxaban Therapy: An Affordable and Reliable Strategy?" Clinical and Applied Thrombosis/Hemostasis 25 (January 1, 2019): 107602961983505. http://dx.doi.org/10.1177/1076029619835053.

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Dabigatran and rivaroxaban, direct oral anticoagulants (DOACs), affect coagulation tests, and knowledge of their effects is important for therapeutic monitoring. Our aim was to examine the association between DOAC levels and routine coagulation tests in patients with nonvalvular atrial fibrillation. Samples from patients receiving dabigatran (150 mg) and patients receiving rivaroxaban (20 mg) were collected 2 hours after drug intake. Direct oral anticoagulant concentrations were determined using direct Hemoclot thrombin inhibitor (HTI) assay (HTI test) and a direct Xa inhibitor (Anti Xa-Riva).

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Lombardo, R., F. Cepparrone, G. Di Pietro, C. Franco, G. Graziani, and G. Avanzi. "Plasma Exchange in Systemic Lupus Erythematosus. Experience in Thirty-seven Patients." International Journal of Artificial Organs 16, no. 5_suppl (1993): 177–79. http://dx.doi.org/10.1177/039139889301605s38.

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Thirty-seven (37) SLE patients submitted to therapeutic plasmapheresis were examined. The results were good in the active stage of the disease. Various types of antibody, anti-DNA, anti nucleus, anti-cardiolipine, I.C. (Clq and C3d) were removed. The values of IgG, coagulation factors, creatinine and proteinuria were assessed. Close collaboration with the clinicians is urged, with the aim of applying immunosuppressive therapy immediately after P.E. to consolidate the results obtained.

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Saja, Khalid. "Addendum to the guideline on the peri‐operative management of anti‐coagulation and anti‐platelet therapy." British Journal of Haematology 197, no. 2 (2022): 188–89. http://dx.doi.org/10.1111/bjh.18114.

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Wyld, Melanie LR, Philip A. Clayton, Rachael L. Morton, and Steven J. Chadban. "Anti-coagulation, anti-platelets or no therapy in haemodialysis patients with atrial fibrillation: A decision analysis." Nephrology 18, no. 12 (2013): 783–89. http://dx.doi.org/10.1111/nep.12170.

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Chekhonin, E. S., and O. A. Pavlovskiy. "ANTI-VEGF THERAPY FOR DIABETIC RETINOPATHY." Bulletin of Pirogov National Medical & Surgical Center 19, no. 4 (2024): 119–23. http://dx.doi.org/10.25881/20728255_2024_19_4_s1_119.

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Diabetic retinopathy is one of the most severe complications of diabetes mellitus, requiring the participation of doctors of various specialties: endocrinologists, diabetologists, therapists, cardiologists, surgeons, anesthesiologists and others.The task of an ophthalmologist is to identify pathological changes in the eye associated with diabetes mellitus and prescribe appropriate treatment.There are three main methods for treating diabetic retinopathy: laser coagulation of the retina;intravitreal injections of anti-VEGF and glucocorticoids;vitreoretinal surgery.This literature review examines

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Fedoruk, N. A., and R. T. Usmanova. "Management tactics for patients with neovascular glaucoma." Modern technologies in ophtalmology 60, no. 2 (2025): 152–53. https://doi.org/10.25276/2312-4911-2025-2-152-153.

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Relevance Secondary neovascular glaucoma (NVG) is characterized by the most severe course and requires a systematic approach to treatment [1]. Objective To evaluate modern approaches to the treatment of NVG, allowing to achieve the maximum possible effect. Material and methods More than 50 scientific papers have been analyzed from 2007 to the present. Data on the pathogenesis, modern diagnostic methods and new technologies in the treatment of NVG have been studied. Results Multiple studies confirm the crucial importance of the formation of retinal ischemia and pathological angiogenesis as the

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Cerenzia, Eric Gaetano, Tyler W. Stratton, Daniel Mackeigan та ін. "Thiol Isomerase Activity of β 3 Integrin Psi Domain and L33P Polymorphism: Implications in Blood Coagulation and Anti-Thrombotic Therapy". Blood 138, Supplement 1 (2021): 1052. http://dx.doi.org/10.1182/blood-2021-151294.

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Abstract Background: Integrins are α and β subunit heterodimeric receptors expressed ubiquitously on metazoan cells that play key roles in cell adhesion, movement, and signaling. The αIIbβ3 integrin on platelets is essential for thrombosis and hemostasis through its binding of fibrinogen and other ligands to mediate platelet adhesion and aggregation. The plexin-semaphorin-integrin (PSI) domain is an approximately 54 amino acid sequence at the N-terminus of the β3 subunit located in close proximity to the "knee" region. Our lab recently discovered that two "CXXC" motifs within PSI domains in th

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Hawes, Emily M., Allison M. Deal, Dorothy M. Adcock, et al. "Performance of coagulation tests in patients on therapeutic doses of rivaroxaban." Thrombosis and Haemostasis 111, no. 06 (2014): 1133–40. http://dx.doi.org/10.1160/th13-10-0871.

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SummaryKnowledge of anticoagulation status during rivaroxaban therapy is desirable in certain clinical situations. It was the study objective to determine coagulation tests most useful for assessing rivaroxaban’s anticoagulant effect. Peak and trough blood samples from 29 patients taking rivaroxaban 20 mg daily were collected. Mass spectrometry and various coagulation assays were performed. “On-therapy range” was defined as the rivaroxaban concentrations determined by LC-MS/ MS. A “misprediction percentage” was calculated based on how often results of each coagulation assay were in the normal

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Nesti, Martina, Fabiana Lucà, David Duncker, et al. "Antiplatelet and Anti-Coagulation Therapy for Left-Sided Catheter Ablations: What Is beyond Atrial Fibrillation?" Journal of Clinical Medicine 12, no. 19 (2023): 6183. http://dx.doi.org/10.3390/jcm12196183.

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Aim: International guidelines on the use of anti-thrombotic therapies in left-sided ablations other than atrial fibrillation (AF) are lacking. The data regarding antiplatelet or anticoagulation strategies after catheter ablation (CA) procedures mainly derive from AF, whereas for the other arrhythmic substrates, the anti-thrombotic approach remains unclear. This survey aims to explore the current practices regarding antithrombotic management before, during, and after left-sided endocardial ablation, not including atrial fibrillation (AF), in patients without other indications for anti-thromboti

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Boross, Peter, Cafer Yildiz, Kamran Bakhtiari, Joost C. M. Meijers, and C. Erik Hack. "Towards Restoring Coagulation in Hemophilia By Antibody-Mediated Inhibition of Antithrombin." Blood 126, no. 23 (2015): 550. http://dx.doi.org/10.1182/blood.v126.23.550.550.

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Abstract Currently hemophilia A is mainly treated with factor VIII (FVIII). However, 20-25% of the hemophiliacs develop inhibiting antibodies (inhibitors) against FVIII. Hemophiliacs with inhibitors are treated with high dose FVIII or with therapies that bypass the need for FVIII such as activated FVII (rFVIIa, NovoSeven) or activated prothrombin concentrate. These have some disadvantages including rapid clearance, price and a risk of thrombo-embolism. In hemophilia, the balance between coagulation and anticoagulation is shifted towards the latter. This balance can be restored by administratio

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Crosby, Jeff, Dacao Gao, Chenguang Zhao, et al. "Systematic Evaluation of Coagulation Factors as Targets for Anti-Thrombotic Therapy Using Antisense Technology." Blood 114, no. 22 (2009): 4181. http://dx.doi.org/10.1182/blood.v114.22.4181.4181.

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Abstract Abstract 4181 Human clinical efficacy has been demonstrated with antisense oligonucleotides (ASOs) in several disease indications, including dyslipidemia, cancer, diabetes and multiple sclerosis. Second generation ASOs show potent pharmacology in many tissues, with liver being one of the most sensitive to ASO action. As the liver is responsible for production of many of the factors involved in blood coagulation we systematically designed and evaluated ASOs selective for several members of the coagulation cascade. ASOs targeting coagulation cascade members of both the intrinsic and ext

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Cate, Hugo ten, Henri M. H. Spronk, and Sarah T. B. G. Loubele. "Anticoagulant therapy in critical organ ischaemia/reperfusion injury." Thrombosis and Haemostasis 104, no. 07 (2010): 136–42. http://dx.doi.org/10.1160/th09-08-0582.

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SummaryIschaemia/reperfusion (I/R) injury is central to a number of pathologies including myocardial infarction and stroke. Several cellular processes are involved in the progress of I/R injury, involving complex interactions between coagulation and inflammatory or apoptotic processes. Besides for their anti-coagulant function, anticoagulant proteins such as activated protein C (APC), active site inhibited factor VIIa (ASIS), tissue factor pathway inhibitor (TFPI), and antithrombin (AT) are also known for their anti-inflammatory or cell protective effects. This review gives an overview of the

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Butar, Yosua Butar, Yetti Hernaningsih, and Narazah Mohd Yusoff. "The Role of Thromboelastography in Heparin Therapy for COVID-19 Patients." Jurnal Respirasi 8, no. 2 (2022): 119–25. http://dx.doi.org/10.20473/jr.v8-i.2.2022.119-125.

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The 2019 coronavirus disease (COVID-19)-associated coagulopathy one of the significant complications often found in hospitalized COVID-19 patients. A hypercoagulable and prothrombotic state characterize coagulopathy with an increased risk of thrombotic events. Abnormal coagulation tests could predict bleeding risk, thrombosis, and disease severity. In addition to increasing the D-dimer, prolonged prothrombin time has decreased survival and increased treatment requirements. Based on laboratory findings, it was reported that 70% of patients with COVID-19 had disseminated intravascular coagulatio

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Bondar, M. V., M. M. Pylypenko, and O. A. Loskutov. "COVID-19: cytokine storm and anticytokine therapy." EMERGENCY MEDICINE 17, no. 2 (2021): 6–13. http://dx.doi.org/10.22141/2224-0586.17.2.2021.230629.

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This review describes in detail one of the key links in the pathogenesis of COVID-19 — the overproduction of pro-inflammatory cytokines that play a key role in the formation of acute respiratory distress syndrome, disseminated intravascular coagulation, multiple organ dysfunction syndromes, and causes high mortality among patients infected with COVID-19. The article deals with the basic directions of intensive therapy for the prevention of development as well as the treatment of cytokine storm and drugs for anti-cytokine therapy. Among drugs with anti-cytokine and anti-inflammatory properties,

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Chen-yang, Jiang, Zhao Li-li, Wang Jian-an, San Jiang, and Mohammod Balgaith. "Anticoagulation therapy in intra-aortic balloon counterpulsation: Does IABP really need anti-coagulation?" Journal of Zhejiang University-SCIENCE A 4, no. 5 (2003): 607–11. http://dx.doi.org/10.1631/jzus.2003.0607.

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Alcock, R., C. Naoum, B. Aliprandi-Costa, F. Davidson, S. Chandar, and D. Brieger. "The Management of Anti-coagulation Therapy in Patients Undergoing Elective Non-cardiac Surgery." Heart, Lung and Circulation 19 (January 2010): S227. http://dx.doi.org/10.1016/j.hlc.2010.06.551.

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Muthiah, Aravind, Shabarini Srikumar, PraveenBharath Saravanan, and Shridharan Perumal. "Anti-coagulation therapy on COVID-19 patients: A systematic review and meta-analysis." Lung India 39, no. 6 (2022): 562. http://dx.doi.org/10.4103/lungindia.lungindia_114_22.

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Allan, Jennifer, and Richard Thompson. "Does Pre-Operative Anti-Coagulation Therapy Impact Morbidity Following Regional Lymph Node Dissection?" European Journal of Surgical Oncology 45, no. 11 (2019): 2197. http://dx.doi.org/10.1016/j.ejso.2019.09.012.

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Thomas, D. E., Z. Yousef, and R. A. Anderson. "Novel Pharmacological Interventions to Maintain Sinus Rhythm after DC Cardioversion." ISRN Cardiology 2011 (July 12, 2011): 1–7. http://dx.doi.org/10.5402/2011/176834.

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Despite the availability of potentially curative interventions for atrial fibrillation, there remains an important role for conventional anti-arrhythmic therapy and anti-coagulation combined with direct current cardioversion. Unfortunately, the latter approach is disturbed by high recurrence rates of atrial fibrillation. In recent years, several adjunctive therapies have emerged which may facilitate the maintenance of sinus rhythm. These novel therapies and their potential mechanisms of action are reviewed in this article.

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Alzahrani, Azzah, Nada Othman, Tahani Bin-Ali, et al. "Routine Preoperative Coagulation Tests in Children Undergoing Elective Surgery or Invasive Procedures: Are They Still Necessary?" Clinical Medicine Insights: Blood Disorders 12 (January 2019): 1179545X1882115. http://dx.doi.org/10.1177/1179545x18821158.

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Introduction: Preoperative coagulation screening tests in pediatric patients was once routine clinical practice globally and still used as standard practice in some countries before surgical procedures to assess of perioperative bleeding risk. Objective: The study aimed to evaluate unselected routine preoperative coagulation testing in children undergoing elective or invasive surgery to predict abnormal perioperative bleeding. The study also aimed to provide a rational approach of determining bleeding and family history of coagulation disorders as a predictive risk for bleeding. Methods: This

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Ozawa, K., K. Tazawa, D. Kishida, K. Fukushima, M. Matsuda, and S. Ikeda. "Transient pulmonary edema following Adrenal Infarction in a patient with primary Anti-phospholipid syndrome." Clinical Medicine Insights: Case Reports 5 (January 2012): CCRep.S10808. http://dx.doi.org/10.4137/ccrep.s10808.

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We report a patient with primary anti-phospholipid syndrome (APS) who developed pulmonary edema following sudden-onset pain in the left, lower back of the chest. Radiological examinations demonstrated fresh infarction of the left adrenal gland but no obvious thrombi in pulmonary arteries. The patient quickly recovered from pulmonary edema with anti-coagulation therapy alone. Primary APS may have caused adrenal infarction in the patient, leading to transient pulmonary edema via microthrombosis and/or excessive release of catecholamine.

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Alsaikhan, Bader, and Sero Andonian. "Shock wave lithotripsy in patients requiring anticoagulation or antiplatelet agents." Canadian Urological Association Journal 5, no. 1 (2013): 53. http://dx.doi.org/10.5489/cuaj.566.

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Extracorporeal shockwave lithotripsy (SWL) remains the only trulyminimally invasive procedure for the treatment of upper tract nephrolithiasis.Recently, there has been a recent rise in the patientson antiplatelet agents. Therefore, the aim of the present study isto review the literature available regarding SWL in these high-riskpatients requiring anti-coagulation therapy. Alternative therapiesto SWL are also presented.

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Ng, Charles Jun Han, Cheng Boon Poh, Sreekanth Koduri, et al. "Regional citrate anti-coagulation dose titration: impact on dose of continuous renal replacement therapy." Clinical and Experimental Nephrology 25, no. 9 (2021): 963–69. http://dx.doi.org/10.1007/s10157-021-02064-1.

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Post, Michał, Dorota Polakowska, Karolina Bonińska, and Jacek P. Szaflik. "Sulodexide Therapy for the Treatment of Diabetic Retinopathy." Ophthalmology, no. 3 (December 30, 2023): 43–45. http://dx.doi.org/10.5114/oku/178043.

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Diabetes mellitus is causing dysfunction of the vascular endothelial cells, which results in various pathologies within the microvascular and macrovascular system including retinopathy, neuropathy, nephropathy, and angiopathy. Endothelial dysfunction is caused by hyperglycemia via different mechanisms, such as damage to the glycocalyx, activation of the inflammation, oxidative stress, stimulation of cellular senescence, induction of imbalance between coagulation and fibrinolysis. Many studies suggests that inhibition of retinal endothelial dysfunction may be an effective way of slowing the pro

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Jarczak, Dominik, Stefan Kluge, and Axel Nierhaus. "Use of Intravenous Immunoglobulins in Sepsis Therapy—A Clinical View." International Journal of Molecular Sciences 21, no. 15 (2020): 5543. http://dx.doi.org/10.3390/ijms21155543.

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Sepsis is a life-threatening organ dysfunction, defined by a dysregulated host immune response to infection. During sepsis, the finely tuned system of immunity, inflammation and anti-inflammation is disturbed in a variety of ways. Both pro-inflammatory and anti-inflammatory pathways are upregulated, activation of the coagulation cascade and complement and sepsis-induced lymphopenia occur. Due to the manifold interactions in this network, the use of IgM-enriched intravenous immunoglobulins seems to be a promising therapeutic approach. Unfortunately, there is still a lack of evidence-based data

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Nozaki, Miho, Ryota Ando, Toshiya Kimura, Fusae Kato, and Tsutomu Yasukawa. "The Role of Laser Photocoagulation in Treating Diabetic Macular Edema in the Era of Intravitreal Drug Administration: A Descriptive Review." Medicina 59, no. 7 (2023): 1319. http://dx.doi.org/10.3390/medicina59071319.

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Background and Objectives: This study aimed to elucidate the role of laser photocoagulation therapy in the treatment of diabetic macular edema (DME) as an alternative to, or in conjunction with, the first-line treatment, anti-vascular endothelial growth factor (VEGF). Materials and Methods: A comprehensive literature search to identify studies that evaluated the efficacy of laser photocoagulation therapy in the management of DME was performed. The relevant findings of the efficacy of focal/grid laser therapy from data in randomized, controlled trials were synthesized, and the potential of new

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Spence, J. David, Tilo Grosser, and Garret A. FitzGerald. "Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension." Hypertension 79, no. 9 (2022): 1922–26. http://dx.doi.org/10.1161/hypertensionaha.122.19315.

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Acetaminophen is widely regarded as a safe therapy for pain and fever in patients with cardiovascular disease and those taking anticoagulants. However, recent studies report that acetaminophen, like most other nonsteroidal anti-inflammatory drugs, increases blood pressure, and a formulation containing sodium increases cardiovascular risk. Those findings call into question guidelines recommending acetaminophen for patients with cardiovascular disease and pain, and those taking anticoagulants. We review evidence that acetaminophen has effects in common with nonsteroidal anti-inflammatory drugs,

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Oliver, Jeremie D., Emma P. DeLoughery, Nikita Gupta, et al. "Local Pro- and Anti-Coagulation Therapy in the Plastic Surgical Patient: A Literature Review of the Evidence and Clinical Applications." Medicina 55, no. 5 (2019): 208. http://dx.doi.org/10.3390/medicina55050208.

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The risks of systemic anti-coagulation or its reversal are well known but accepted as necessary under certain circumstances. However, particularly in the plastic surgical patient, systemic alteration to hemostasis is often unnecessary when local therapy could provide the needed adjustments. The aim of this review was to provide a summarized overview of the clinical applications of topical anti- and pro-coagulant therapy in plastic and reconstructive surgery. While not a robust field as of yet, local tranexamic acid (TXA) has shown promise in achieving hemostasis under various circumstances, he

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Kaiko, Gerard E., Feidi Chen, Chin-Wen Lai, et al. "PAI-1 augments mucosal damage in colitis." Science Translational Medicine 11, no. 482 (2019): eaat0852. http://dx.doi.org/10.1126/scitranslmed.aat0852.

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There is a major unmet clinical need to identify pathways in inflammatory bowel disease (IBD) to classify patient disease activity, stratify patients that will benefit from targeted therapies such as anti–tumor necrosis factor (TNF), and identify new therapeutic targets. In this study, we conducted global transcriptome analysis to identify IBD-related pathways using colon biopsies, which highlighted the coagulation gene pathway as one of the most enriched gene sets in patients with IBD. Using this gene-network analysis across 14 independent cohorts and 1800 intestinal biopsies, we found that,

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Pisaryuk, Alexandra S., Nikita M. Povalyaev, Alexander V. Poletaev, and Alexey M. Shibeko. "Systems Biology Approach for Personalized Hemostasis Correction." Journal of Personalized Medicine 12, no. 11 (2022): 1903. http://dx.doi.org/10.3390/jpm12111903.

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The correction of blood coagulation impairments of a bleeding or thrombotic nature employs standard protocols where the type of drug, its dose and the administration regime are stated. However, for a group of patients, such an approach may be ineffective, and personalized therapy adjustment is needed. Laboratory hemostasis tests are used to control the efficacy of therapy, which is expensive and time-consuming. Computer simulations may become an inexpensive and fast alternative to real blood tests. In this work, we propose a procedure to numerically define the individual hemostasis profile of

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Permana, Septian Adi, and Muhammad Markam Shalihin. "The use of antivenom serum, fresh frozen plasma, and platelet concentrate for management strategy of snakebite related coagulopathy: a case series." Anaesthesia, Pain & Intensive Care 27, no. 6 (2023): 750–56. http://dx.doi.org/10.35975/apic.v27i6.2250.

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Snakebite is a medical emergency. It can cause local and systemic effects in humans. Different venomous snakes produce different types of venom, which can cause a variety of symptoms and complications. The scarcity of anti-snake venom serum (SABU) in Indonesia encourages alternative administration strategies to patients, namely suboptimal doses or subdose. Three cases of adult patients with a history of snakebite and diagnosed with snakebite grade III were reported. The patient underwent initial antivenom therapy using suboptimal doses of anti-snake venom serum (SABU) due to the scarcity

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