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Rozprawy doktorskie na temat „Antihyperglycemia”

Autor: Grafiati
Data publikacji: 3 czerwca 2025
Data aktualizacji: 31 lipca 2025

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Sprawdź 38 najlepszych rozpraw doktorskich naukowych na temat „Antihyperglycemia”.

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1

MacKinnon, Lindsay M. "Self-adjusting doses of oral antihyperglycemic therapy using repaglinide or glyburide in type 2 diabetes : the soaring study." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98758.

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Cette etude pilote de six mois examinait si l'autogestion (AG) intensive par un agent secreteur d'insuline avait pour consequence une glycemie amelioree en comparaison avec une gestion standard (GS) chez les individus atteints de diabete de type 2. Des patients ont ete randomises soit a l'AG avec du repaglinide (n=8), ou du glyburide (n=6) ou a la GS (n=5). Des analyses biochimiques, alimentaires, comportementales, et d'activite physique ont ete effectuees. Les deux groupes de l'AG ont recu un enseignement d'autogestion en fonction du taux de glucose sanguin et une evaluation nutritionnelle qu
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PELE, TOUNIAN AGNES. "Etude pharmacologique et mecanistique chez le rat d'un derive imidazolinique antihyperglycemiant le s-22068 (pms 847)." Paris 7, 1998. http://www.theses.fr/1998PA077123.

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Le s-22068, un nouveau compose imidazolinique, s'est recemment avere tres efficace pour ameliorer la tolerance au glucose dans un modele experimental de rat fonde sur l'injection d'une faible dose de streptozotocine (35 mg/kg). Nous avons recherche les mecanismes d'action possibles a l'origine de son effet antihyperglycemiant. En utilisant la technique de perifusion d'ilots isoles nous avons retrouve, in vitro, la legere augmentation de la secretion d'insuline prealablement observee in vivo. Cette augmentation s'explique en partie par la capacite du s-22068 a induire directement la fermeture d
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Almarhoon, Zahra M. B. S. "Geographic Variation in the Utilization of Antihyperglycemic Therapies in the U.S. Medicaid Program at State-Level Using Geographic Information System." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1553618550167677.

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Bartmus, Thomas. "A systematic review and mixed treatment comparison assessing the comparative effectiveness and safety of oral antihyperglycemic drugs as monotherapy in patients with type 2 diabetes mellitus." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-171555.

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Bartmus, Thomas [Verfasser], and Ulrich [Akademischer Betreuer] Mansmann. "A systematic review and mixed treatment comparison assessing the comparative effectiveness and safety of oral antihyperglycemic drugs as monotherapy in patients with type 2 diabetes mellitus / Thomas Bartmus. Betreuer: Ulrich Mansmann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/105807671X/34.

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Alsadeg, Aborus Naji Elhadi. "Fitohemijske i funkcionalne karakteristike praškastih formi klijanaca pšenice, ovsa i ječma." Phd thesis, Univerzitet u Novom Sadu, Tehnološki fakultet Novi Sad, 2017. http://www.cris.uns.ac.rs/record.jsf?recordId=104607&source=NDLTD&language=en.

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U radu su ispitani fitohemijski profil, antioksida-tivna i in vitro biološka aktivnost ekstrakata klijanaca šest sorti žitarica: pšenica Spelt, Simonida, (WSSPE, WSSIM) ječam, hibrid “NS565” (Hordeum vulgare L. ssp distichum.) (BSNS) i ne-hibridni “Golozrni” (Hordeum vul-gare var nudum.) (BSG) i ovas Golozrni, Jadar (OSG, OSJ). U cilju poređenja šest istraživanih vrsta klijanaca ispitivanja su obuhvatila određivanje TPC, TFC, TChl, Chla, Chlb i TCX vrednosti i testiranje njihove biološke aktivnosti (antioksidativnog kapaciteta, redukci
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Aleksandra, Gavarić. "Savremene metode ekstrakcije očajnice (Marrubium vulgare L.) i sušenje odabranih ekstrakata, hemijski sastav i biološke aktivnosti." Phd thesis, Univerzitet u Novom Sadu, Tehnološki fakultet Novi Sad, 2020. https://www.cris.uns.ac.rs/record.jsf?recordId=114456&source=NDLTD&language=en.

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U okviru ove disertacije ispitane su mogućnosti primene savremenih metoda za dobijanje tečnih ekstrakata (ultrazvučna ekstrakcija, mikrotalasna ekstrakcija i ekstrakcija subkritičnom vodom) i lipofilnih ekstrakata (ekstrakcija superkritičnim ugljendioksidom) bogatih polifenolima iz nadzemnog dela očajnice (Marrubium vulgare L.). Tečni ekstrakti su optimizovani primenom eksperimentalnog dizajna i metode odzivne površine, i podvrgnuti su spray drying tehnici sušenja. Tečni i suvi ekstrakti su detaljno ispitani po pitanju hemijskog sastava i biološke aktivnosti, antimikrobne
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Miodrag, Jazić. "Hemijski sastav i biološki potencijal ploda, soka i tropa kultivisane i divlje kupine (Rubus fruticosus L.)." Phd thesis, Univerzitet u Novom Sadu, Tehnološki fakultet Novi Sad, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=111236&source=NDLTD&language=en.

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U okviru ove disertacije ispitan je hemijski, mineralni ipolifenolni sastav, kao i biološki potencijal četiri sortekupina sa dva različita lokaliteta sjeverozapadnog dijelaBosne i Hercegovine, sa lokaliteta Verići (divlja ikultivisana sorta Čačanska bestrna) i sa lokalitetaJavorani (divlja sorta i kultivisana sorta ChesterThornles). Određen je sadržaj suve materije, pepela,sirove celuloze, ukupnih šećera, ukupna kiselost i sadržajaskorbinske kiseline. Sadržaj mineralnih materijadetektovan je metodom optičke emisione spektrometrije(ICP-OES). Za izdvajanje ekstrakata je kori&scaron
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Niu, Ho-Shan, and 牛河山. "Antihyperglycemic action of syringin." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/05019971685134411930.

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博士<br>臺北醫學大學<br>藥學系(博士班)<br>98<br>In streptozotocin-induced diabetic rats (STZ-diabetic rats), the type-1 diabetes-like animal model, the mechanism(s) of antihyperglycemic action produced by syringin, an active principle purified from the rhizome part of Eleutherococcus senticosus (Araliaceae),was investigated . Bolus intravenous (i.v.) injection of syringin for 30 min dose-dependently decreased the plasma glucose of STZ-diabetic rats in a way parallel to the increase of plasma ??-endorphin-like immunoreactivity (BER). Syringin enhanced BER release from the isolated adrenal medulla of STZ-diab
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Ke, Ya-Fang, and 柯雅芳. "Antihyperglycemic Action of Catalpol." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/96111222974348780639.

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碩士<br>國立成功大學<br>藥理學研究所<br>91<br>Catalpol, a monoterpene compound ，was isolated from “Die-Huang”. Catalpol produced a dose-dependent hypoglycemic action in streptozotocin -induced diabetic rats after an intravenous injection (i.v.). Catalpol at the effective dose (0.1mg/kg) significantly attenuated the increase of plasma glucose induced by intravenous glucose challenge test in Wistar rats. In vitro, catalpol enhanced the uptake of 14C 2-deoxy-glucose (2-DG) into skeletal muscle in a concentration-dependent manner. In the hepatocytes isolated from diabetic rats, catalpol also increased the synth
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Shiao, Gan-Chao, and 蕭晏詔. "Antihyperglycemic Action of Myricetin." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/d596k8.

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碩士<br>國立成功大學<br>藥理學研究所<br>90<br>. Myricetin produced a dose-dependent hypoglycemic action in streptozotocin-induced diabetic rats after an intravenous injection (i.v.). Myricetin at the effective dose (1mg/kg) significantly attenuated the increase of plasma glucose induced by intravenous glucose challenge test in Wistar rats. In vitro, myrivetin enhanced the uptake of [14C] 2-deoxy-glucose (2-DG) into skeletal muscle in a concentration-dependent manner. In the hepatocytes isolated from diabetic rats, myricetin also increased the synthesis of glycogen. Myricetin enhanced the uptake of radioacti
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Yang, Tzyy-Lin, and 楊紫麟. "Antihyperglycemic Effect of Valsartan." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/pw76y3.

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碩士<br>國立成功大學<br>藥理學研究所<br>90<br>Valsartan is clinically used in the management of hypertension. In the present study, a dose-dependent lowering of plasma glucose level was observed in both fasting streptozotocin (STZ)-induced diabetic rats and Wistar rats after intravenous injection of valsartan at 30 min. Valsartan at effective dose (0.2mg/kg, i.v.) significantly attenuated the increase of plasma glucose induced by intravenous glucose challenge test in Wistar rats. Injection of valsartan at the effective dose increased plasma β-endorphin concentration in STZ-diabetic rats. Plasma glucose lowe
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Yu, Bu-chin, and 游步青. "Antihyperglycemic action of andrographolide." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/y5k76m.

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碩士<br>國立成功大學<br>藥理學研究所<br>90<br>In the present study, the antihyperglycemic action and possible mechanism of andrographolide were investigated. A dose-dependent lowering of plasma glucose was observed both in the streptozotocin (STZ)-induced diabetic rat and Wistar rats, after oral treatment (P.O.) of andrographolide. Andrographolide at an effective dose significantly attenuated the increase of plasma glucose induced by intravenous glucose challenge test in Wistar rats. Stimulatory effects of andrographolide on the glucose uptake and glycogen synthesis were also obtained in soleus muscles and
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Yun-WenLai and 賴韻文. "Antihyperglycemic action of sinapic acid." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/72297288035469936689.

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碩士<br>國立成功大學<br>藥理學研究所<br>98<br>Diabetes is a metabolic disorder associated with chronic inflammation and increased oxidative stress. Sinapic acid (SA) is a cinnamic acid derivative that has anti-inflammatory and anti-oxidative capacities. However, the effects of SA on diabetes remain unclear. In the present study, we found that oral administration of SA in streptozocin-induced diabetic rats exerted a blood glucose lowering effect while increased plasma β-endorphin was also observed. Previous studies have been demonstrated that activation of α1-adrenoceptor (α1-AR) in adrenal gland is responsi
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Yun-Chueh, Chen, and 陳韻玨. "Antihyperglycemic effect of caffeic acid." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/53005490032112453487.

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碩士<br>國立成功大學<br>藥理學研究所<br>87<br>Diabetes mellitus (DM) is one of the common diseases in clinics. In an attempt to develop the new compounds to treat DM, caffeic acid, the compound isolated from the stems of Xanthium sibiricum patrin (Composita), was investigated to know the antihyperglycemic mechanisms. Three types of rats were employed to screen the antihyperglycemic activity of caffeic acid. Wistar rats as normal control were compared with the streptozotocin(STZ)-induced diabetic rats which are similar to the patients with insulin-dependent DM (IDDM) and the rats with insulin-resistance (NID
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Huang, Ching-chiu, and 黃瀞萩. "Investigation of antihyperglycemic mechanism of Metformin." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/42072432099257467300.

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碩士<br>國立成功大學<br>藥理學研究所<br>91<br>In the present study, the antihyperglycemic action and possible mechanism of metformin were investigated. A dose-dependent lowering of plasma glucose was observed both in the diabetic rats lacking insulin and Wistar rats, after oral treatment of metformin. Metformin at an effective dose significantly attenuated the increase of plasma glucose induced by intravenous glucose challenge test in Wistar rats that indicated an increase of glucose utilization by metformin. In our previous study, we found that ?-endorphin is responsible for production of hypoglycemic effe
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Hsu, Sheng-Fa, and 許勝發. "Antihyperglycemic Action of Die-Huang-Wan." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/aa9fqj.

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碩士<br>國立成功大學<br>藥理學研究所<br>90<br>Die-Huang-Wan is prepared by a mixture of 6 herbs. In Chinese traditional medicine, Die-Huang-Wan is one of the prescriptions for handling of diabetic disorders and this herbal mixture has also been used for a long time in Japan and other Asian area. In an attempt to develop agents without side effect for good handling of diabetes mellitus, Die-Huang-Wan was investigated in the present study. Oral of Die-Huang-Wan produced a dose-dependent hypoglycemic action in Wistar rats. Atropine or scopolamine at an effective dose significantly attenuated the Die-Huang-Wan-
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Lai, Chih-Wei, and 賴致瑋. "The mechanisms of antihyperglycemic action of paeoniflorin." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/50790976494596402032.

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碩士<br>國立成功大學<br>藥理學研究所<br>85<br>In an attempt to develop the new compounds for the treatment of diabetes mel litus (DM), screen of antihyperglycemic activity is carried out from the extra cts of natural plants in three types of diabetic rats; the streptozotocin (STZ )-induced one and the genetic one (B.B. rats) which is similar to the patients with insulin-dependent DM (IDDM) and the NIDDM (non-insulin-dependent DM rats ) one . Paeoniflorin, the compound isolated from Paeoniae Radix, was found to have mo
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Huang, Lee-Wen, and 黃莉雯. "The Mechanisms of Antihyperglycemic Action of Tetrandrine." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/97088212470373456107.

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碩士<br>國立成功大學<br>藥理學研究所<br>89<br>Diabetes mellitus (DM) is one of the metabolic disorders due to the deficiency of insulin secretion and/or a reduction in the effectiveness of insulin. In order to have more drugs for handling of DM, the present study performed the development of active compounds from natural plants. Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the root of Stephania tetrandra S. Moore (Menispermaceae), was investigated. Tetrandrine produced a dose-dependent hypoglycemic action in streptozotocin-induced diabetic rats after an intravenous injection (i.v.). Tetrandri
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Su, Hui-Chen, and 蘇慧真. "Antihyperglycemic mechanisms of puerarin, a natural product." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/80684588096405786032.

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碩士<br>國立成功大學<br>藥理學研究所<br>89<br>Diabetes mellitus (DM ) is one of the metabolic disorders. It has been established that the patients of DM increased in the development of countries. However, drugs for the handling of DM seem not enough. Thus, R & D of new agent is required in recent. Puerarin is one of the active principles in the root of Pueraria lobata Willd.( Leguminosae ). In the present study, the antihyperglycemic mechanism of puerarin was investigated. A dose-dependent lowering of plasma glucose was observed in the both fasting streptozotocin (STZ)-induced diabetic rat and W
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Chen, Pei-Fen, and 陳佩芬. "Investigation of antihyperglycemic mechanism of Ginsenoside Rh2." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/18197519478733607480.

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碩士<br>國立成功大學<br>藥理學研究所<br>92<br>In an attempt to develop agent with less side for handling of diabsts mellitus, the antihyperglycemic action and possible mechanism of ginsenoside Rh2 (G-Rh2) from Panax ginseng C.A. Meyer, was investigated in the present study. Oral administration of ginseng powder produced a dose-dependent hypoglycemic action in Wistar rats, but failed to lower plasma glucose in streptozocin (STZ) –induced diabetic rats. Thus, release of insulin seems responsible for the lowering of plasma glucose in Wistar rats by ginseng powder. G-Rh2 also produced a dose-dependent hypoglyce
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Hsu, Chia-Chen, and 許家禎. "Antihyperglycemic Mechanism of Diosmin in Diabetic Rats." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/69dq34.

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博士<br>國立屏東科技大學<br>食品科學系所<br>106<br>Diosmin, a natural flavone glycoside, is widely contained in citrus and antihyperglycemic effect has been documented in animals although the action mechanism(s) remained unknown. The present study is aimed to investigate the potential mechanisms of diosmin in reduction of hyperglycemia. In streptozotocin (STZ)-induced type 1-like diabetic rats, an animal model unrelated to endogenous insulin, injection of diosmin induced a dose-dependent decrease of hyperglycemia. Also, plasma -endorphin was raised by diosmin in parallel. Antihyperglycemic effect of diosmin w
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I-Min, Liu, and 劉怡旻. "Antihyperglycemic Mechanisms of a Natural Product, Isoferulic Acid." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/08373696424902972693.

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博士<br>國立成功大學<br>基礎醫學研究所<br>89<br>Diabetes mellitus (DM) is one of the serious disorders around the world. Cimicifuga rhizoma is contained in the prescription of “Bu-Zhong-I-Chi-Tang”, a medication to be effective for the handling of DM in traditional Chinese medicine. Isoferulic acid is one of the active prinicles in Cimicifuga rhizoma. The present study is performed to investigate the antihyperglycemic action of isoferulic acid. A dose-dependent lowering of plasma glucose was obtained in the fasting rats with insulin dependent DM, both Bio—Breeding/Worcester rats and steptozotocin-
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Yu-HuaKuo and 郭玉華. "Antihyperglycemic action of allantoin in type 2 diabetes." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/72476692378490254842.

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SU, YI-CHUN, and 蘇宜君. "Antihyperglycemic effect of moraceae extract in diabetic mice." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/ukg59f.

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碩士<br>長榮大學<br>醫學研究所<br>107<br>Diabetes is a common metabolic disease. According to the World Health Organization, diabetes will become the seventh leading cause of death in the world in 2030. The regulation of blood glucose is an important factor in avoiding the complications of diabetes. To reduce the mortality rate of diabetes, many researchers have tried to use natural extract to improve the symptoms of hyperglycemia. This research is to explore whether the extracts of Moraceae can effectively improve the symptoms of hyperglycemia in diabetic mice. The experiment induced mice into two group
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Chen, Pei-Chi, and 陳佩琦. "Antihyperglycemic effect of 3-Hydroxy-3-methylglutaric acid (HMG)." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/68302562691570377299.

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碩士<br>國立成功大學<br>藥理學研究所<br>88<br>Diabetes mellitus (DM) is one of the chronic diseases in clinics. Many complications are accompanied by this disease, and decreased quality of life. Therefore, in an attempt to develop the new compounds for the treatment of DM, screen of antihyperglycemic activity is carried out from the extracts of natural plants in diabetic rats, that were induced by streptozotocin. On the other hand, Wistar rats as normal control. 3-Hydroxy-3-methylglutaric acid (HMG), the compound isolated from Tillandsia usneolides L. (Bromeliaceae). In vivo, HMG produced a dose-depnedent h
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Chi, Tzong-Cherng, and 紀宗呈. "Antihyperglycemic action of agmatine in streptozotocin-induced diabetic rats." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/67536745355311040310.

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碩士<br>國立成功大學<br>藥理學研究所<br>87<br>Agmatine, decarboxylated arginine, is an endogenous agonist for imidazoline receptors in brain. In streptozotocin (STZ)-induced diabetic rats (IDDM), the plasma glucose lowering action was produced dose-dependently after an intravenous injection of agmatine from 0.5 mg/kg to 3.0 mg/kg. However, agmatine did not affect the plasma triglycerides or cholesterol in these rats. Also, agmatine had no effect on the glucose uptake into isolated soleus mucle. Idazoxan, an antagonist of imidazoline receptor, reversed this antihyperglycemic action of agmatine in a dose-d
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Lin, Yi-Tzu, and 林怡慈. "Antihyperglycemic effects of the aqueous extracts from guava fruit." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/71340530855607872693.

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碩士<br>國立屏東科技大學<br>熱帶農業暨國際合作系所<br>98<br>The present study investigated the effect of guava fruit aqueous extracts on blood glucose regulation and carbohydrate metabolism in diabetic rats. The experiment comes to two parts which were antioxidant capacity of guava fruit aqueous extracts and animal model experiment. In the first part, guava fruits were extracted with hot water 80℃for 30 minutes by the way to boil tea; the extract powders were obtained to be our experimental samples by centrifugating and freeze-drying, and then analyzed its general composition and antioxidative activity. In the sec
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Liu, Pi-Yu, and 劉碧玉. "Antihyperglycemic Effect of Hydrolysate of Chlorella and Freshwater Clam." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/29311886720431019642.

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碩士<br>國立臺灣海洋大學<br>食品科學系<br>100<br>pulverized chlorella and freshwater clam were used as new material in this study. Pulverized chlorella were hydrolyzed by cellulase and protease at 50℃ for 3 hours. The freshwater clam muscle was extracted using hot water. The residual meat was first freeze-dried, then hydrolyzed at 50oC by protease to obtain freshwater clam hydrolysate. The inhibitory effect of Chlorella (CH) and freshwater clam hydrolysates (PX) on activity of α-glucosidase and DPP4 (dipepidy peptidase 4) were investigated, and the physiological effect on regulation of blood sugar was also e
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Liu, Ko-Yu, and 劉科佑. "Antihyperglycemic actions and Antihypertensive actions of Eleutherococcus senticosus and syringin." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/80634631129171852227.

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碩士<br>高雄醫學大學<br>天然藥物研究所碩士班<br>92<br>Xie-Wu-Jia is the Chinese of herb Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. It is also named as Siberian Ginseng because the same family (Araliaceae) as ginseng. In an attempt to develop the agent suitable for patients with diabetes and hypertension, Xie-Wu-Jia was investigated in the present study. Oral administration of Xie-Wu-Jia produced a dose-dependent decrease of plasma glucose in Wistar rats. Intravenous injection of syringin into Wistar rats, one of the active principles of Xie-Wu-Jia, resulted in a reduction of plasma glucose. Increase of
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Chao, Jingdong. "The relationship between depressive symptoms and oral antihyperglycemic medication adherence." 2004. http://books.google.com/books?id=RkZtAAAAMAAJ.

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Chiu, Lan Chi, and 邱嵐琪. "Antihyperglycemic and antioxidative potential of Psidium guajava in STZ-induced diabetic rats." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/23669297627376652603.

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碩士<br>亞洲大學<br>保健營養生技學系碩士班<br>98<br>Psidium guajava (PG) is an important tropical fruit, widely consumed fresh and also processed (beverages, syrup, and jams), and rich in vitamin C and flavonoids. Several studies suggested that the extract from PG leaves possesses antidiabetic effects in diabetic mice model and these effects are speculated to account its polyphenolic compounds. Oxidative stress play a crucial role in the development of diabetic complications The aims of this study were to investigate whether PG could reduce hyperglycaemic and ameliorate oxidative stress of the streptozotocin (
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Lin, Yen-Chu, and 林彥竹. "Antihyperglycemic Effect and Mechanism of KS-C370G on ICR Mice and Cultured Cell Lines." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/05299112912693855902.

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碩士<br>國立臺灣大學<br>藥理學研究所<br>97<br>KS-C370G is a derivative of caffeic acid phenethyl ester (CAPE), an active component of propolis, which has several biological and pharmacological properties similar to CAPE or even better. Our previous research has shown that KS-C370G has an antidiabetic effects in streptozotocin -induced diabetic mice and high-fat-induced type 2 diabetic mice. In acute treatment, KS-C370G can reduce fasting blood glucose in both STZ-induced diabetic mice and high-fat induced type 2 diabetic mice. In chronic treatment, KS-C370G can also lower the fasting blood glucose and rever
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su-lien, Kuo, and 郭素蓮. "Investigation of antihyperglycemic effect on diabetic rats and its mutagenicity of Pinus morrisonicola hayata." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/46403746976810209400.

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碩士<br>國立屏東科技大學<br>食品科學系<br>92<br>Abstract Pinus exhibits not only reducing the blood cholesterol but also lowering the blood glucose. The purpose of the current study is to investigate the function of Pinus morrisonicola hayata powder in modulating blood glucose by using Wistar rats as an animal model, and to evaluate the toxicity and mutagenicity of Pinus morrisonicola hayata powder and its extracts. In modulating of blood glucose, the Wisrar rats were employed and introduced nicotinamide (230mg/kg) and streptozotocin (65 mg/kg) for diabetic induction. After continuous 6 weeks feed
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Cheng, Ching-Hung, and 鄭景鴻. "Studies on the Antihyperglycemic Constituents of Hibiscus taiwanensis Hu and Flemingia philippinensis Merr. et Rolfe." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/50513577853306361181.

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Hung, Hsin-Jung, and 洪心容. "Studies on the Relationship between Antioxidant and Antihyperglycemic Activities of Nine Antidiabetic Medicinal Plants Originated from Taiwan." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/98317975762478221699.

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碩士<br>中國醫藥大學<br>中國藥學研究所<br>96<br>Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from defects in insulin secretion or insulin action. Recent papers indicated that oxidative stress played a central role in the onset of diabetes mellitus as well as in diabetes associated complications. α-Glucosidase is an enzyme that catalyses the final step of glucose absorption in the intestine during the digestive process of carbohydrates. α-Glucosidase inhibitor can retard the rapid utilization of dietary carbohydrates and suppress postprandial hyperglycemia. In the present
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Qi-yun, Huang, and 黃琦雲. "Evaluation of the Antihyperglycemic and Antihypertensive Bioactivities of Fruit Wastes From Different Pomelo Species by Cell Models." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/76kaju.

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碩士<br>弘光科技大學<br>食品科技所<br>106<br>According to the report issued by the International Diabetes Federation (IDF), 425 million people or more have been diagnosed with diabetes, while hypertension and type 2 diabetes are relevantly associated metabolic disorders. Sustained high blood pressure may cause stroke, heart disease, heart failure, chronic renal failure, and so on. Literature indicates that certain plant phenolic compounds can be directly uptaken into the blood, which can scavenge free radicals, chelate metallic ions, activating the antioxidant enzymes and at the same time inactivating the
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Kawa, Julianne Marie. "Characterization of urinary inositol excretion in diabetes mellitus and the antihyperglycemic effects of a buckwheat concentrate, containing D-chiro-inositol." 2005. http://hdl.handle.net/1993/20272.

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