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1

Bhatta, Sabita, Manoj Pradhan, Alina Singh, Raina Chaudhary, and Yankpam Ibotomba Singh. "Antimicrobial Sensitivity Pattern of Pseudomonas Aeruginosa Isolated from a Tertiary Care Hospital." Medical Journal of Shree Birendra Hospital 19, no. 2 (2020): 70–74. http://dx.doi.org/10.3126/mjsbh.v19i2.28380.

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Introduction: Pseudomonas aeruginosa (P. aeruginosa) is one of the major cause of nosocomial infection. Multi-drug-resistant P. aeruginosa (MDR PA) are increasingly encountered in clinical samples .Therefore, this study was undertaken to know the sensitivity pattern of P. aeruginosa and to detect MDR PA from clinical samples.
 Methods: This was a laboratory based retrospective-cross sectional study conducted at Department of Microbiology at a tertiary care referral centre in Kathmandu, Nepal from December 2018 to December 2019. Total of 200 isolates of P. aeruginosa were isolated from cli
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Shahriar, M., and S. Akter. "A Survey on Antimicrobial Sensitivity Pattern of Different Antibiotics on Clinical Isolates of Pseudomonas aeruginosa Collected from Dhaka City of Bangladesh." Journal of Scientific Research 3, no. 1 (2010): 187. http://dx.doi.org/10.3329/jsr.v3i1.6014.

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A study of antimicrobial sensitivity of Pseudomonas aeruginosa isolated from clinical sources from different diagnostic centers, Dhaka, Bangladesh was carried out to facilitate the preference of drug in the management of Pseudomonas aeruginosa induced symptoms. Very low sensitivity of P. aeruginosa towards co-trimoxazole (45%), azithromycin (30%) and erythromycin (35%) was observed. Higher sensitivity pattern was observed for cefuroxime (57.5%). and only imipenem (100%) has shown sensitivity pattern possibly susceptible enough to consider for the management of P. aeruginosa induced cases in th
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Sieswerda, Elske, Thijs Bosch, Jacqueline M. Lankelma, Leo M. Schouls, and Karin van Dijk. "Vitek® 2 MICs as first-line phenotypic screening method for carbapenemase-producing Pseudomonas aeruginosa." Future Microbiology 16, no. 11 (2021): 777–81. http://dx.doi.org/10.2217/fmb-2020-0024.

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Aim: To define sensitivity and specificity of Vitek® 2 MICs as phenotypic screening method for carbapenemase-producing Pseudomonas aeruginosa. Materials & methods: We determined Vitek® 2 MICs of antipseudomonal antimicrobials in 130 unrelated carbapenemase-producing P. aeruginosa and 129 carbapenemase-negative P. aeruginosa isolates within a Dutch carbapenemase-surveillance database. We calculated test characteristics of single and combined antimicrobial MICs for carbapenemase production. Results: Vitek® 2 MIC above epidemiological cutoff of both imipenem and tobramycin or ciprofloxacin an
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Khare, Anubhuti, Saroj Kothari, and Vaibhav Misra. "Incidence and sensitivity pattern of Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa in a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 6, no. 2 (2017): 329. http://dx.doi.org/10.18203/2319-2003.ijbcp20170324.

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Background: Antimicrobial resistance is a serious problem worldwide and differs from region to region. This study was planned to determine the incidence and sensitivity pattern of Klebsiella pneumoniae (K. pneumoniae), Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa) in our region and discuss the general issues related to antimicrobial resistance.Methods: Prospective study was carried out between March to October 2015. Samples of urine, blood, pus, CSF and miscellaneous samples (fluids, swabs, sputum and stool) were collected from indoor and outdoor patients for isolation
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WAHYUDI, MARIANA, and Antonius Adji Prayitno Setiadi. "PENGOLEKSIAN ISOLAT- ISOLAT Pseudomonas aeruginosa DARI PASIEN DI SURABAYA DAN PEMETAAN KEPEKAANNYA TERHADAP BERBAGAI MACAM ANTIBIOTIKA." Sains & Teknologi 1, no. 3 (2019): 35. http://dx.doi.org/10.24123/jst.v1i3.2236.

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The investigation about collectivity and sensitivity test of Pseudomonas aeruginosa from patient in Surabaya have been done. The aim of this research is to collect the bacteria from patient and to know the profile of their sensitivity toward the variety of antimicrobial agents. P. aeruginosa isolates were collected from two microbiological laboratory in Surabaya. Then, each isolate was purified and reconfirmed of few of its properties. Purified P. aeruginosa collections were then store in –70oC . Sensitivity test for each isolate was done toward 13 kinds of antimicrobial agents. The conclusion
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Reece, Emma, Pedro H. de Almeida Bettio, and Julie Renwick. "Polymicrobial Interactions in the Cystic Fibrosis Airway Microbiome Impact the Antimicrobial Susceptibility of Pseudomonas aeruginosa." Antibiotics 10, no. 7 (2021): 827. http://dx.doi.org/10.3390/antibiotics10070827.

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Pseudomonas aeruginosa is one of the most dominant pathogens in cystic fibrosis (CF) airway disease and contributes to significant inflammation, airway damage, and poorer disease outcomes. The CF airway is now known to be host to a complex community of microorganisms, and polymicrobial interactions have been shown to play an important role in shaping P. aeruginosa pathogenicity and resistance. P. aeruginosa can cause chronic infections that once established are almost impossible to eradicate with antibiotics. CF patients that develop chronic P. aeruginosa infection have poorer lung function, h
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Parveen, Nighat, Vineeta Khare, Sarah Hassan, and Syed Abid Asghar. "PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF PSEUDOMONAS AERUGINOSA ISOLATED FROM VARIOUS CLINICAL SAMPLES AT ELMC&H." Era's Journal of Medical Research 10, no. 01 (2023): 25–28. http://dx.doi.org/10.24041/ejmr2023.4.

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To identify P. aeruginosa prevalence in different clinical samples along with to. Evaluate its antibiotic sensitivity method isolated from variety of clinical. Over the course of the six- month trial period, 1200 samples in total were analyzed. To identify and isolate P. aeruginosa, each of them underwent direct microscopy and culture. In this study 63 P. aeruginosa were isolated and identified out of 1200 clinical samples. Pus and urine were where the majority of P. aeruginosa were isolated from specimens. There found sensitivity to Piperacilin- tazobactam (10µg) 35% and Gentamycin (10µg) 38%
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Deecken, B. P., F. Freitas, K. V. Bassetto, A. G. Strider, and B. G. Castro. "Fracture exposed in Blue-yellow-macaw (Ara ararauna, L., 1758) infected with multiresistant Pseudomonas aeruginosa - Case Report." Scientific Electronic Archives 13, no. 11 (2020): 56. http://dx.doi.org/10.36560/131120201081.

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Antibiotics are used to prevent or treat bacterial infections; however, the emergence of antimicrobial resistance is one of the major problems in human and veterinary medicine. Little is known about the prevalence of bacterial antimicrobial resistant associated with wild animals. Moreover, birds are susceptible to several bacterial pathogens common to man. In this sense, Pseudomonas aeruginosa has great relevance, causing infections when the host's defense mechanisms are reduced. The objective of this study was to report a case of isolation of a multidrug-resistant strain of P. aeruginosa in a
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AL-Sabagh, Fadi S. H., Kais K. Ghaima, and Alhan H. Sh.AL-Dabbagh. "The antibacterial activity of LL-37 peptide against multidrug-resistant Pseudomonas aeruginosa isolated from burn infections." Bionatura 8, no. 1 (2023): 1–5. http://dx.doi.org/10.21931/rb/2023.08.01.69.

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Multidrug-resistant Pseudomonas aeruginosa has emerged as a significant problem worldwide, posing a severe hazard to burn-infected patients. Antimicrobial peptides produced from humans or animals and synthetic peptides have received interest as antibiotic options for treating resistant bacteria, particularly those obtained from burn patients. The current work evaluated the role of antimicrobial peptide LL-37 as an antibacterial agent against multidrug P. aeruginosa isolates from burn infections. The study samples were collected between November 2021 and the end of February 2022 and included 15
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Ameen, Syed S., Shanmukananda Prakash, Laxminarayana Bairy K., and Shahabuddin Soherwardi. "Antimicrobial drug sensitivity pattern of Pseudomonas aeruginosa in respiratory infections." International Journal of Basic & Clinical Pharmacology 6, no. 7 (2017): 1591. http://dx.doi.org/10.18203/2319-2003.ijbcp20172635.

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Background: Pseudomonas aeruginosa, a gram-negative pathogen commonly associated with nosocomial infections is the most widespread multidrug-resistant pathogen causing pneumonia in hospitalized patients. Inadequate empirical therapy has been associated with high mortality and morbidity. Objective: To evaluate and analyze the antimicrobial susceptibility pattern of P. aeruginosa in respiratory infections in a tertiary care hospital.Methods: The study was carried out at Kasturba Hospital, Manipal from Jan 2011 to Dec 2011. Specimens of 63 in-patients were analyzed who were culture positive for P
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Epifanova, Natalia Yu. "Modern approaches to the treatment of infections caused by Pseudomonas aeruginosa with multiple antimicrobial resistance. What a practicing physician should know." Supportive Therapy in Oncology 2, no. 2 (2025): 44–60. https://doi.org/10.17650/3034-2473-2025-2-2-44-60.

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The rise of antimicrobial resistance is a pressing problem worldwide. Oncology patients are at risk of developing infections caused by multidrug-resistant bacteria. This is associated with frequent visits of patients to hospitals for chemotherapy courses, long periods of neutropenia in oncohematologic patients and after hematopoietic stem cell transplantation, repeated courses of antibiotic therapy, surgical interventions, etc.Aim of this work – to familiarize physicians with the mechanisms of antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa), the possibilities and limitations
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Morsy, MM, HK Sorour, ZS Abdel Razek, and AG Shalaby. "Genetic profiling of virulence genes among Pseudomonas Aeruginosa isolates recovered from diseased chickens." Journal of the Hellenic Veterinary Medical Society 75, no. 3 (2024): 8055–64. http://dx.doi.org/10.12681/jhvms.36434.

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Pseudomonas aeruginosa (P. aeruginosa) is regarded as an opportunistic organism for bird species. Also is one can be mentioned as an example of an environment-associated infection that results in severe disease in poultry farms, Indeed, we detected the incidence of P. aeruginosa in chickens and also discovered the implicated virulence genes and antibiotic-resistant mechanism. Two hundred cases were collected from broiler and layer chicken organs (heart blood, heart, and lungs) that suffered from some respiratory manifestation and septicemia in addition to yolk sacs from one-day-old chicks, whi
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de Souza, Paula Araujo, Milena Cristina Silva dos Santos, Rebeca Vitória da Silva Lage de Miranda, et al. "Evaluation of Antimicrobial Resistance Patterns of Pseudomonas aeruginosa Strains Isolated among COVID-19 Patients in Brazil Typed by Fourier-Transform Infrared Spectroscopy." Life 14, no. 9 (2024): 1079. http://dx.doi.org/10.3390/life14091079.

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This study aimed to characterize Pseudomonas aeruginosa strains isolated from hospitalized patients during the COVID-19 pandemic. This was achieved using phenotypic and molecular techniques, including their antimicrobial resistance profile and biofilm formation. Eighteen strains were isolated from a hospital in Rio de Janeiro, Brazil, and identified by VITEK®2, MALDI-TOF/MS (VITEK MS® and MALDI Biotyper®), and 16S rRNA sequencing. Fourier-transform infrared (FTIR) spectroscopy, antimicrobial susceptibility testing, and biofilm formation and disinfectant tolerance tests were applied to evaluate
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Berdeu, Ion. "Antimicrobial resistance profile of Pseudomonas aeruginosa strains." Public Health, Economy and Management in Medicine, no. 4(101) (October 2024): 63–79. https://doi.org/10.52556/2587-3873.2024.4(101).10.

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Antimicrobial resistance is one of the most serious threats facing humanity today. Th e majority of pathogens on the WHO list with high resistance to antibiotics are Gram-negative bacteria, including Pseudomonas. Data on the etiological structure of septico-purulent infections (SPIs), multiple antibiotic resistance of microorganisms isolated from patients hospitalized at the Institute of Emergency Medicine were analyzed. Gram-positive bacteria accounted for 40,15% among the isolated strains, with a predominance of Enterococcus faecalis, Staphylococcus aureus and Staphylococcus epidermidis spec
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Ishchenko, O. V., and D. O. Stepanskyi. "Microbiological features of Pseudomonas aeruginosa in children with Cystic Fibrosis." Medicni perspektivi (Medical perspectives) 26, no. 3 (2021): 131–38. http://dx.doi.org/10.26641/2307-0404.2021.3.242130.

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The purpose of the study was to determine the frequency rate of Pseudomonas aeruginosa infection among children with cystic fibrosis (CF) in Dnipro region and to provide microbiological characteristics of the obtained isolates. The study was conducting from January 2019 to December 2020. Children with genetically confirmed CF diagnosis were enrolled. The main research method was bacteriological with identification of microorganisms by biochemical properties; antimicrobial susceptibility was determined by disk-diffusion method. Biological material: mucus from a deep smear from the posterior pha
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Ishchenko, O.V., and D.O. Stepanskiy. "Microbiological features of Pseudomonas aeruginosa in children with Cystic Fibrosis." Medicni perspektivi 26, no. 3 (2021): 131–38. https://doi.org/10.26641/2307-0404.2021.3.242130.

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<strong>&nbsp;</strong>The purpose of the study was to determine the frequency rate of Pseudomonas aeruginosa infection among children with cystic fibrosis (CF) in Dnipro region and to provide microbiological characteristics of the obtained isolates. The study was conducting from January 2019 to December 2020. Children with genetically confirmed CF diagnosis were enrolled. The main research method was bacteriological with identification of microorganisms by biochemical properties; antimicrobial susceptibility was determined by disk-diffusion method. Biological material: mucus from a deep smear
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Dr., Muhammad Ihtisham Javed Dr. Hadiqa Javed Dr. Maham Bashir. "A PROSPECTIVE DESCRIPTIVE RESEARCH TO ASSESS THE P. AERUGINOSA FREQUENCY & ANTIMICROBIAL RESISTANT STRAINS IN BRONCHIECTASIS CASES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 10506–12. https://doi.org/10.5281/zenodo.1467719.

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<strong><em>Objective: </em></strong><em>We aimed to discover the presence and frequency of Pseudomonas aeruginosa multiple antimicrobial resistant strains (P. aeruginosa) in Post tuberculosis (TB) bronchiectasis patients.</em> <strong><em>Methodology: </em></strong><em>We carried out this prospective descriptive research at TB OPD of Sir Ganga Ram Hospital, Lahore from October 2016 to May 2017. Patients gave their consent and samples before research commencement. The total sixty patients were in the age bracket of more than forty years, with </em><em>bronchiectasis (suspected). These patients
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Gondal, Aamir Jamal, Nakhshab Choudhry, Ammara Niaz, and Nighat Yasmin. "Molecular Analysis of Carbapenem and Aminoglycoside Resistance Genes in Carbapenem-Resistant Pseudomonas aeruginosa Clinical Strains: A Challenge for Tertiary Care Hospitals." Antibiotics 13, no. 2 (2024): 191. http://dx.doi.org/10.3390/antibiotics13020191.

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Carbapenem-resistant Pseudomonas aeruginosa (P. aeruginosa) strains have become a global threat due to their remarkable capability to survive and disseminate successfully by the acquisition of resistance genes. As a result, the treatment strategies have been severely compromised. Due to the insufficient available data regarding P. aeruginosa resistance from Pakistan, we aimed to investigate the resistance mechanisms of 249 P. aeruginosa strains by antimicrobial susceptibility testing, polymerase chain reaction for the detection of carbapenemases, aminoglycoside resistance genes, extended-spect
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Bahniuk, N., M. Faustova, K. Riesbeck, et al. "THE CORRESPONDENCE OF THE CARBAPENEMASE GENOTYPE AND PHENOTYPIC ANTIMICROBIAL PROFILES OF PSEUDOMONAS AERUGINOSA." Medical and Ecological Problems 27, no. 5-6 (2023): 45–50. http://dx.doi.org/10.31718/mep.2023.27.5-6.06.

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The aim of the study was to determine the correspondence between the carbapenemase genotype and the phenotypic antimicrobial profiles of P. aeruginosa. Materials and methods. The study included 51 clinical isolates of P. aeruginosa, isolated from the patients with post-operative complications of the respiratory organs. The final identification of the obtained isolates was performed in the Riesbeck laboratory using MALDI-ToF (Bruker), followed by the determination of their sensitivity to antimicrobial drugs at the EUCAST Development Laboratory (Växjö, Sweden). Determination of the resistance ge
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Hakim, Ashraf S., Sohad M. Dorgham, Hussein A. Abuelhag, et al. "Isolation and identification of Pseudomonas aeruginosa obtained from dogs and cats in Great Cairo regarding status of phenotypic antimicrobial resistance pattern." Egyptian Pharmaceutical Journal 23, no. 3 (2024): 525–31. http://dx.doi.org/10.4103/epj.epj_340_23.

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Background Companion animals; dog and cat are closely associated with the daily life of humans and may be implemented in the transmission of many microorganisms to their adopters. Pseudomonas aeruginosa (P. aeruginosa) is a suited opportunistic and harsh to treat pathogen due to its rife environmental distribution, unique intrinsic and acquired resistance to numerous antimicrobials’ categories. Objective The current study targeted to survey the existence of P. aeruginosa in laboratory samples obtained from diseased dogs and cats. The study also investigated the susceptibility and resistance of
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Ahmed Hamdy Badr, Mohamed Sherif, Ahmed Abdelaziz Sayed, and Mostafa Mohamed Elnakib. "Effects of extremely low-frequency electromagnetic fields on the susceptibility and resistance mechanisms of multi-drug resistant Pseudomonas aeruginosa." GSC Advanced Research and Reviews 12, no. 1 (2022): 091–100. http://dx.doi.org/10.30574/gscarr.2022.12.1.0187.

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The purpose of this study is to assess the impact of low-frequency electromagnetic fields (LF-EMFs = 0.5 MHz) on the phenotypic and genotypic levels concerning the antibiotic resistance, antimicrobial-resistant (AMR) genes, and resistance mechanisms of Pseudomonas aeruginosa (P. aeruginosa). In this study, the bacterial isolates were exposed to 0.5 MHz and then inoculated to a new medium for the assessment of their antibiotic sensitivity. The results showed that there were statistically significant changes in the antibiotic sensitivity upon exposure to extremely low-frequency waves along with
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Ahmed, Hamdy Badr, Sherif Mohamed, Abdelaziz Sayed Ahmed, and Mohamed Elnakib Mostafa. "Effects of extremely low-frequency electromagnetic fields on the susceptibility and resistance mechanisms of multi-drug resistant Pseudomonas aeruginosa." GSC Advanced Research and Reviews 12, no. 1 (2022): 091–100. https://doi.org/10.5281/zenodo.7151362.

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The purpose of this study is to assess the impact of low-frequency electromagnetic fields (LF-EMFs = 0.5 MHz) on the phenotypic and genotypic levels concerning the antibiotic resistance, antimicrobial-resistant (AMR) genes, and resistance mechanisms of&nbsp;<em>Pseudomonas aeruginosa (P. aeruginosa)</em>. In this study, the bacterial isolates were exposed to 0.5 MHz and then inoculated to a new medium for the assessment of their antibiotic sensitivity. The results showed that there were statistically significant changes in the antibiotic sensitivity upon exposure to extremely low-frequency wav
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С.А., Кишилова, та Рожкова И.В. "Оценка эффективности действия синегнойного бактериофага к штаммам Pseudomonas aeruginosa". Food processing industry, № 11 (29 жовтня 2024): 77–81. http://dx.doi.org/10.52653/ppi.2024.11.11.014.

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Устойчивость микроорганизмов к различным антимикробным веществам резко возросла за последние десятилетия, а вместе с ней и опасность проникновения резистентных бактерий в пищевые цепочки человека. Существенную проблему для эффективной санитарной обработки на предприятиях пищевой, в том числе молочной, отрасли создает способность микроорганизмов к образованию биопленок, удаление которых стандартными методами, как правило, нерезультативно. Особое значение в связи с этим имеет условно-патогенная бактерия Pseudomonas aeruginosa, как чрезвычайно активный биопленкообразователь и микроорганизм, спосо
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Pourmohammadi, Naser, Reza Shapouri, Mohammadreza Nahaei, and Mojtaba Mohammadi Roknabadi. "Genotypic Investigation of Antibiotic Resistance: Presence of BlaOXA-48 Gene in Clinical Isolates of Pseudomonas aeruginosa." Avicenna Journal of Clinical Microbiology and Infection 11, no. 2 (2024): 62–67. http://dx.doi.org/10.34172/ajcmi.3508.

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Background: Identifying antimicrobial resistance patterns and antibiotic resistance genes in clinical isolates of Pseudomonas aeruginosa is an important strategy for effectively combating infections. This study aimed to identify the antimicrobial resistance patterns and the presence of blaOXA-48 beta-lactamase gene in P. aeruginosa isolated from clinical samples. Methods: We collected 100 isolates of P. aeruginosa from different clinical samples, including urine, tracheal tube, blood, and burn wounds. The antimicrobial resistance patterns of the isolates were investigated using the disk diffus
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Daji, Morumda, Tolulope Iorwuese Ade, Hyelnaya Shamdama Cletus, Aisha Muhammad Bello, and Panshak Joseph. "Antimicrobial Resistance Pattern of Clinical Isolates of Pseudomonas aeruginosa from Urinary Tract Infections in Wukari, Taraba state, Nigeria." Journal of Biochemistry, Microbiology and Biotechnology 10, no. 2 (2022): 25–28. http://dx.doi.org/10.54987/jobimb.v10i2.753.

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Pseudomonas aeruginosa is a potent nosocomial pathogen of immunocompromised individuals, causing several infections while also resisting chemotherapy with conventional antimicrobial agents. Hence, this study was carried out to determine the antimicrobial resistance pattern of P. aeruginosa associated with urinary tract infections (UTIs) in Wukari, Taraba State. Thirty (30) voided midstream urine were collected from clinically diagnosed UTI patients attending Wukari general hospital and cultured aerobically on MacConkey agar and cysteine-lactose-electrolyte-deficient (CLED) agar. Bacterial isol
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Mohsin, Yusra Mb, Huda Zuheir Majeed, Ali Murtatha Hasan, and Enaam Hamed Bataah. "SUSCEPTIBILITY PATTERN OF PSEUDOMONAS AERUGINOSA PRODUCING ENZYMES AGAINST ANTIMICROBIAL AGENT CELL FREE SUPERNATANT OF LACTOCOCCUS WITH THE FOCUS ON ITS DETERMINING QUANTITATIVELY BY OD (ENZYME LINKED IMMUNE SORBENT ASSAY)." Asian Journal of Pharmaceutical and Clinical Research 10, no. 3 (2017): 291. http://dx.doi.org/10.22159/ajpcr.2017.v10i3.16188.

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ABSTRACTObjective: The present work was conducted to explore the prevalence of Pseudomonas aeruginosa that produce lipase and protease enzymes in40 samples, as well as detection of quality and quantity production and determine its susceptibility to antimicrobial.Methods: The antimicrobial activity of Lactococcus cell free supernatant (CFS) on P. aeruginosa growth and quantity production of enzymes by twomethods (special media and OD) were also studied.Results: A total of 8(20%) and 13(32%) isolates were found to be positive to P. aeruginosa producing lipase and protease, respectively. The in v
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ULLAH, G., F. AHSAN, S. FARRUKH, MA QAISRANI, M. YASIN, and M. AKHTAR. "ANTIMICROBIAL SENSITIVITY PATTERN OF PEDIATRIC CYSTIC FIBROSIS PATIENTS IN PAKISTAN." Biological and Clinical Sciences Research Journal 2023, no. 1 (2023): 492. http://dx.doi.org/10.54112/bcsrj.v2023i1.492.

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Cystic fibrosis (CF) is a complex genetic disorder affecting the respiratory and digestive systems, causing recurrent infections. This study aimed to evaluate the microbiological cultures and identify the patterns of antimicrobial sensitivity among young CF patients in Pakistan. This prospective observational study was conducted at the Pakistan Institute of Medical Sciences (PIMS) from December 2021 to November 2022, involving comprehensive assessments, interviews, clinical tests, MTs, CBCs, CXRs, sputum cultures, RBS measurements, microbiological analysis of sputum and oropharyngeal swabs, an
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Lyamin, A. V., M. O. Zolotov, O. V. Kondratenko, E. A. Maksimova, D. D. Ismatullin, and P. V. Bochkareva. "Prevalence of antimicrobial-resistant Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis." Meditsinskiy sovet = Medical Council, no. 20 (November 17, 2023): 114–20. http://dx.doi.org/10.21518/ms2023-346.

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Introduction. Violation of sputum evacuation in patients with cystic fibrosis leads to the persistence of microorganisms. Most often, the microorganisms are isolated from sputum in patients with cystic fibrosis: Staphylococcus aureus, Pseudomonas aeruginosa, Burkholderia cepacia complex, etc. For the treatment of infections caused by P. aeruginosa, the following groups of antibiotics are used: aminoglycosides, carbapenems, polymyxins, cephalosporins, fluoroquinolones, inhibitor-protected penicillins and fosfomycin.Aim. To the study is to determine antimicrobial resistance in P. aeruginosa isol
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Maesum Ali, Saleh Khurshied, Altaf Hussain, Muhammad Ali, and Ali Khurshid. "Comparison of Current Bacteriological Profile and Antibiotic Sensitivity Pattern in Tubotympanic Type of Chronic Suppurative Otitis Meida between Adult and Pediatric Patients Presenting at Tertiary Care Hospital in Islamabad Pakistan." Indus Journal of Bioscience Research 3, no. 5 (2025): 613–17. https://doi.org/10.70749/ijbr.v3i5.1353.

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Background: CSOM, in its tubotympanic variety, continues to be one of the most common causes of a preventable cause of a hearing loss in developing countries, among both children and adults. Appreciating the prevailing bacteriological trends as well as antibiotic sensitivity patterns is crucial to the intervention as an increasing antimicrobial resistance loom over the horizon. Aim: To compare the present bacteriology and sensitivity of the antibiotics of adult and pediatric cases of tubotympanic type of CSOM attending a tertiary care hospital in Islamabad Pakistan. Methods: This comparative c
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Popova, T. P., and I. Ignatov. "In vitro antimicrobial activity of colloidal nano silver." BULGARIAN JOURNAL OF VETERINARY MEDICINE 26, no. 2 (2023): 168–81. http://dx.doi.org/10.15547/bjvm.2411.

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The antimicrobial effect of colloidal nanosilver (AgNPs) at concentrations of 20 and 30 ppm against reference Esherichia coli, Salmonella enterica, Staphylococcus aureus, Clostridium perfringens, Candida albicans strains and two clinical isolates (Pseudominas aeruginosa and Streptococcus pyogenes) was tested. The classical agar diffusion method, determination of the minimum inhibitory concentrations (MIC) and the time of antimicrobial action of AgNPs were used. In the studies performed by the agar diffusion method, a very good inhibitory effect of AgNPs 30 ppm and to a much lesser extent of Ag
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AL-Khikani, Falah, and Alae Ayit. "The Antibacterial Action of Safranin and Gentian Violet." Rambam Maimonides Medical Journal 13, no. 3 (2022): e0018. http://dx.doi.org/10.5041/rmmj.10475.

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Background: The increasing resistance of many bacterial pathogens against antibiotic measures urgently requires new or repurposing therapeutic strategies. Gentian violet is a triarylmethane dye used as a histological stain and for Gram’s method of classifying bacteria. It also exerts an antimicrobial effect against certain pathogens, especially dermatological infections. Safranin is the most popular counterstain used in medical laboratories due to its low cost and safe laboratory usage. However, few studies have been conducted on the antimicrobial activity of safranin. Objective: With the grow
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Omer, Thweaba Hassan Salih, Samia Ali Mohammed Mustafa та Sagad Omer Obeid Mohamed. "Extended Spectrum β-Lactamase-Mediated Resistance and Antibiogram of Pseudomonas aeruginosa Isolates from Patients Attending Two Public Hospitals in Khartoum, Sudan". International Journal of Microbiology 2020 (23 жовтня 2020): 1–5. http://dx.doi.org/10.1155/2020/2313504.

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Treating infections caused by Pseudomonas aeruginosa is challenging. In addition to its intrinsic ability to develop resistance to multiple classes of antibiotics, it also produces extended-spectrum β-lactamase (ESBL). Continuous update of the antibiograms is required to cope with the rate of the emergence of antibiotic resistance. This study aimed to determine the antimicrobial susceptibility pattern and to determine the frequency of ESBL production among the P. aeruginosa isolates from patients at two public military hospitals in Khartoum, Sudan. A total of 34 isolates of P. aeruginosa obtai
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33

Aboyadak, Ibrahim, and Nadia Gabr Ali. "Enrofloxacin, Effective Treatment of Pseudomonas aeruginosa and Enterococcus faecalis Infection in Oreochromis niloticus." Microorganisms 12, no. 5 (2024): 901. http://dx.doi.org/10.3390/microorganisms12050901.

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Enrofloxacin is a broad-spectrum synthetic antimicrobial drug widely used in veterinary medicine. The present study aimed to determine the effective enrofloxacin dose for treating Pseudomonas aeruginosa and Enterococcus faecalis infection in Oreochromis niloticus. P. aeruginosa and E. faecalis isolates were verified using selective differential media and biochemically using the Vitek 2 test. Bacterial isolates were virulent for O. niloticus with LD50 equal to 2.03 × 106 and 2.22 × 107 CFU fish−1 for P. aeruginosa and E. faecalis, respectively. Infected fish suffered from decreased feed intake
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Aghamiri, Samira, Nour Amirmozafari, Jalil Fallah Mehrabadi, Babak Fouladtan, and Hossein Samadi Kafil. "Antibiotic Resistance Pattern and Evaluation of Metallo-Beta Lactamase Genes Including bla-IMP and bla-VIM Types in Pseudomonas aeruginosa Isolated from Patients in Tehran Hospitals." ISRN Microbiology 2014 (April 23, 2014): 1–6. http://dx.doi.org/10.1155/2014/941507.

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Beta-lactamase producing strains of Pseudomonas aeruginosa are important etiological agents of hospital infections. Carbapenems are among the most effective antibiotics used against Pseudomonas infections, but they can be rendered infective by group B β-lactamase, commonly called metallo-beta lactamase. In this study, the antimicrobial sensitivity patterns of P. aeruginosa strains isolated from 9 different hospitals in Tehran, Iran, as well as the prevalence of MBLs genes (bla-VIM and bla-IMP) were determined. A total of 212 strains of P. aeruginosa recovered from patients in hospitals in Tehr
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35

Deslouches, Berthony, Kazi Islam, Jodi K. Craigo, Shruti M. Paranjape, Ronald C. Montelaro, and Timothy A. Mietzner. "Activity of the De Novo Engineered Antimicrobial Peptide WLBU2 against Pseudomonas aeruginosa in Human Serum and Whole Blood: Implications for Systemic Applications." Antimicrobial Agents and Chemotherapy 49, no. 8 (2005): 3208–16. http://dx.doi.org/10.1128/aac.49.8.3208-3216.2005.

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ABSTRACT Cationic amphipathic peptides have been extensively investigated as a potential source of new antimicrobials that can complement current antibiotic regimens in the face of emerging drug-resistant bacteria. However, the suppression of antimicrobial activity under certain biologically relevant conditions (e.g., serum and physiological salt concentrations) has hampered efforts to develop safe and effective antimicrobial peptides for clinical use. We have analyzed the activity and selectivity of the human peptide LL37 and the de novo engineered antimicrobial peptide WLBU2 in several biolo
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36

Taha, Selwan M., Norhan K. Abd El-Aziz, Adel Abdelkhalek, Ioan Pet, Mirela Ahmadi, and Sameh M. El-Nabtity. "Chitosan-Loaded Lagenaria siceraria and Thymus vulgaris Potentiate Antibacterial, Antioxidant, and Immunomodulatory Activities against Extensive Drug-Resistant Pseudomonas aeruginosa and Vancomycin-Resistant Staphylococcus aureus: In Vitro and In Vivo Approaches." Antioxidants 13, no. 4 (2024): 428. http://dx.doi.org/10.3390/antiox13040428.

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Antimicrobial resistance poses considerable issues for current clinical care, so the modified use of antimicrobial agents and public health initiatives, coupled with new antimicrobial approaches, may help to minimize the impact of multidrug-resistant (MDR) bacteria in the future. This study aimed to evaluate the antimicrobial, antioxidant, and immunomodulatory activities of Lagenaria siceraria, Thymus vulgaris, and their chitosan nanocomposites against extensive drug-resistant (XDR) Pseudomonas aeruginosa and vancomycin-resistant Staphylococcus aureus (VRSA) using both in vitro and in vivo ass
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37

Tronza, T. V., A. Yu Voronkova, I. R. Fatkhullina, A. A. Ploskireva, and E. I. Kondratyeva. "Characteristics of the frequency and sensitivity to antimicrobial drugs of Staphylococcus aureus and Pseudomonas aeruginosa isolates of the lower respiratory tract of pediatric patients with cystic fibrosis in the Moscow region." Archives of Pediatrics and Pediatric Surgery 1, no. 2 (2024): 12–23. http://dx.doi.org/10.31146/2949-4664-apps-2-2-12-23.

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Chronic lung infection is the leading cause of death in patients with cystic fibrosis. The article highlights the data of a microbiological examination of children and adolescents with cystic fibrosis living in the Moscow region and the results of determining the antibiotic susceptibility of the main isolated pathogens. The purpose of the study was to study the spectrum of the microflora of the respiratory tract of children and adolescents with cystic fibrosis with the determination of the antibiotic sensitivity of the isolated strains of S. aureus and P. aeruginosa. Material and methods. A st
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Chaudhary, Jitendra Kumar. "A Clinical-Bacteriological Profile of Multidrug Resistant Pseudomonas aeruginosa at Tertiary Care Hospital Shahjahanpur, Uttar Pradesh." International Journal of Current Microbiology and Applied Sciences 10, no. 9 (2021): 301–13. http://dx.doi.org/10.20546/ijcmas.2021.1009.035.

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The Pseudomonas aeruginosa is predominant agent causing nosocomial infections. In recent time, it develops resistance continuously to the antibiotics becomes Multidrug-resistant P. aeruginosa. So, in cystic fibrosis patents it difficult to eradicate P. aeruginosa infections with antimicrobial treatment. Therefore, focus on alternative mechanisms for treating P. aeruginosa infections. On the basis of growth, morphological and biochemical characteristics, P. aeruginosa strains were isolated from the clinical samples in this work. After that the antibiotic sensitivity was performed and the Multid
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39

Dapgh, A. N., A. S. Hakim, H. A. Abouelhag, A. M. Abdou, and E. A. Elgabry. "Detection of virulence and multidrug resistance operons in Pseudomonas aeruginosa isolated from Egyptian Baladi sheep and goat." October-2019 12, no. 10 (2019): 1524–28. http://dx.doi.org/10.14202/vetworld.2019.1524-1528.

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Background: Pseudomonas aeruginosa is a pit of an enormous group of free-living bacteria that are able to live everywhere and suggested to be the causative agent of great scope of acute and chronic animal infections. Aim: The current study was carried out to illustrate the prevalence of P. aeruginosa in small ruminants and existence of some virulence operons as well as its antimicrobial resistance. Materials and Methods: A total of 155 samples from sheep and 105 samples from goats (mouth abscesses, fecal swabs, nasal, tracheal swabs, and lung tissue) were collected for bacteriological study, e
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40

Lavryk, G., I. Tymchuk, T. Rumynska, et al. "Infection with klebsiella and pseudomonas in mine-blast wounds: frequency of their isolation at the third stage of evacuation; spectrum of their resistance; sensitivity to antimicrobial drugs; general rules of military medical care." Lviv clinical bulletin 3-4, no. 43-44 (2024): 29–36. http://dx.doi.org/10.25040/lkv2023.03-04.029.

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Introduction. During the war that has been going on in Ukraine for two years, the number of patients with mine-blast injuries has increased dramatically. The issue of wound colonization by resistant microorganisms and modification of their species spectrum, which increases during the evacuation of victims to various medical facilities, is of great importance. At the third stage of wounded military personnel evacuation 87.7 % of wounds were occupied by gram-negative bacteria in the form of monoculture, including strains of Pseudomonas aeruginosa and Klebsiella pneumoniae with multidrug resistan
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de Sousa, Telma, Catarina Silva, Olimpia Alves, et al. "Determination of Antimicrobial Resistance and the Impact of Imipenem + Cilastatin Synergy with Tetracycline in Pseudomonas aeruginosa Isolates from Sepsis." Microorganisms 11, no. 11 (2023): 2687. http://dx.doi.org/10.3390/microorganisms11112687.

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Pseudomonas aeruginosa is among the most ubiquitous bacteria in the natural world, exhibiting metabolic and physiological versatility, which makes it highly adaptable. Imipenem + cilastatin and tetracycline are antibiotic combinations commonly used to treat infections caused by P. aeruginosa, including serious infections such as sepsis. In the context of bacterial infections, biofilm, formed by bacterial cells surrounded by extracellular substances forming a matrix, plays a pivotal role in the resistance of P. aeruginosa to antibiotics. This study aimed to characterize a representative panel o
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42

Antunes, Bernardo, Caroline Zanchi, Paul R. Johnston, et al. "The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures." PLOS Biology 22, no. 7 (2024): e3002692. http://dx.doi.org/10.1371/journal.pbio.3002692.

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The prevalence of antibiotic-resistant pathogens has become a major threat to public health, requiring swift initiatives for discovering new strategies to control bacterial infections. Hence, antibiotic stewardship and rapid diagnostics, but also the development, and prudent use, of novel effective antimicrobial agents are paramount. Ideally, these agents should be less likely to select for resistance in pathogens than currently available conventional antimicrobials. The usage of antimicrobial peptides (AMPs), key components of the innate immune response, and combination therapies, have been p
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43

Chauhan, P. B., and P. B. Desai. "Antipseudomonal property of honey and aminoglycosides." Journal of Applied and Natural Science 5, no. 2 (2013): 338–41. http://dx.doi.org/10.31018/jans.v5i2.328.

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Pseudomonas aeruginosa has an ability to rapidly develop resistance to most antimicrobial compounds, and to check this ability. The isolates were collected from different pathological human sources and tested for their sensitivity to aminoglycoside antibiotic and to honey, a natural product that is generating renewed interest for its therapeutic application using Kirby Bauer disc diffusion technique. Aminoglycoside antibiotic which is normally active against gram-negative bacteria was used alongside honey. The 29 isolates of P. aeruginosa showed 100%sensitivity to honey tested in their undilut
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A, Kazmi. "Frequency and Antimicrobial Susceptibility Pattern of Pseudomonas Aeruginosa in Human Pus Samples at Holy Family Hospital Rawalpindi." Open Access Journal of Microbiology & Biotechnology 6, no. 1 (2021): 1–8. http://dx.doi.org/10.23880/oajmb-16000189.

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Background: Nosocomial infections are great threat for hospitalized patients and Pseudomonas aeruginosa has emerged as one of the most potent nosocomial pathogens along with its diverse mechanisms to counter the various antimicrobial agents such as aminoglycosides, fluoroquinolones, monobactems, third generation cephalosporins, carbapenams and broad- spectrum penicillins. P. aeruginosa is one of the well-known pyogenic bacteria and is 3rd leading cause of pyogenic infections with the variable frequency depending on geographical region and clinical setting. P. aeruginosa is intimately associate
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45

Braide, W., L.C. Madu, S.A. Adeleye, M.C. Korie, and C.I. Akobondu. "Prevalence of Extended Spectrum Beta Lactamase Producing Escherichia coli and Pseudomonas aeruginosa Isolated from Clinical Samples." International Journal of Sciences Volume 7, no. 2018-02 (2018): 89–93. https://doi.org/10.5281/zenodo.3350233.

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There has been an increasing attention globally over the rising treatment failures caused by Extended Spectrum Beta-Lactamase (ESBL) producing organisms when new generation antibiotics are used. This study was carried out to investigate the prevalence of ESBL producing Escherichia coli and Pseudomonas aeruginosa isolates from the Federal Medical Centre (FMC) Owerri, Imo State, Nigeria. Two hundred and fifty clinical isolates comprising, E. coli (136) and P. aeruginosa (114) was used for the study. Antimicrobial susceptibility testing of isolates was determined using the disc diffusion method.
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Mohammed, Nebras Rada. "Antimicrobial Sensitivity of Pseudomonas aeruginosa to Aztreonam, Amoxicillin, Erythromycin, Carbenicillin, Norfloxacin, Chloramphenicol, Gentamycin and Azithromycin after Exposure to Radiation Emitted from Radioactive Sources, Lasers and Exposure to Magn." European Journal of Theoretical and Applied Sciences 2, no. 4 (2024): 471–81. http://dx.doi.org/10.59324/ejtas.2024.2(4).40.

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Objective: The aim of this study to assess the sensitivity of P. aeruginosa for ATM, AML, E, CAR, NOR, CL, CN and AZM after exposure to radiation emitted from radioactive sources, Lasers and exposure to magnetized water. Study design: Cross-sectional in descriptive study design with case–control in analytical study design Backgrounds: P. aeruginosa gram negative bacteria occasion distinct kinds of contagion including epidermis, optics, ears, respiratory tract, urinary tract, intestines derived sepsis, soft tissues, skeleton and joint contagion. Radiation including ionizing and non-ionization d
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Farhana, Tanzila, Salahuddin Mahmud, Farhana Tasneem, et al. "The burden of antimicrobial resistance among cystic fibrosis patients: an emerging public health concern in tertiary care hospital." Gastroenterology & Hepatology: Open access 16, no. 2 (2025): 67–71. https://doi.org/10.15406/ghoa.2025.16.00610.

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Background: Although Cystic fibrosis (CF), though rare in Bangladesh but it poses significant morbidity due to recurrent respiratory infections and progressive lung damage to the patients. Understanding the microbiological colonization patterns and antimicrobial resistance in Bangladeshi children with CF is important for optimizing the clinical management. Methods: This cross-sectional study was conducted in a period of 12-months at a tertiary pediatric hospital in Bangladesh. Sputum or oropharyngeal swab samples were collected from clinically stable CF patients for microbiological culture and
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48

Leng, Jing, and Jie Yang. "Distribution and antimicrobial susceptibility of pathogenic micro-organisms in pediatric urinary tract infections." Tropical Journal of Pharmaceutical Research 23, no. 7 (2024): 1119–25. http://dx.doi.org/10.4314/tjpr.v23i7.10.

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Purpose: To investigate the prevalence and distribution of pathogenic microorganisms and antimicrobial susceptibility in pediatric urinary tract infections (UTIs). Methods: 150 pediatric patients with UTI diagnosed and treated in Danyang People’s Hospital of Jiangsu Province, China between January 2020 and December 2022 were enrolled. The distribution of pathogenic microorganisms was analyzed using microbial culture and antimicrobial susceptibility test results obtained for major gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumonia). Based on adherence to
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Iqbal, Asif, Iftikhar Ahmad, Sohail Ali, and Rabia Khattak. "Antibiotics resistance pattern of Pseudomonas aeruginosa isolated from different hospitals in Nowshera KPK Pakistan." Journal of Bacteriology & Mycology: Open Access 11, no. 1 (2023): 62–66. http://dx.doi.org/10.15406/jbmoa.2023.11.00345.

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Pseudomonas aeruginosa is an invasive nosocomial pathogen of immunocompromised individuals that mainly affects the respiratory system, urinary tract, burns, and wounds, as well as blood diseases. In this investigation, samples from pus, wound swabs, sputum, blood, and urine were collected to examine the isolation, biochemical identification, and antibiotic resistance pattern against antibiotics of Pseudomonas aeruginosa in Qazi Medical Complex (QMC) and District Headquarter Hospital (DHQ) Nowshera, KPK Pakistan. For biochemical identification, the catalase, oxidase, triple sugar iron, and citr
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Muhammad Aetesam, Nasir, Sher Falak, Saroosh Ifrah, et al. "Antibiotic sensitivity of catheter-associated bacterial pathogens in pediatrics patients." Journal of Clinical Microbiology and Biochemical Technology 9, no. 1 (2023): 014–21. http://dx.doi.org/10.17352/jcmbt.000054.

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Antimicrobial-resistant (AMR) pathogens causing Urinary Tract infection is a serious public health concern in our clinical setting. A total of 200 catheter tips were collected from the different wards (medical, surgical, urology) at the Children’s Hospital Faisalabad. Samples were streaked on nutrient agar plates and the positivity of the samples was noted after 24 hours. Positive samples were processed further for the identification of K. pneumoniae, P. aeruginosa, S. aureus, and E. coli using culture identification, microscopy, and biochemical profiling on the basis of culture characterizati
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