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Artykuły w czasopismach na temat „Antimicrobial susceptibility of S. marcescens”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Mayank Gangwar, and Snehasis Jana. "Assessment of Antibiogram of Biofield Energy Treated Serratia marcescens." European Journal of Preventive Medicine 3, no. 6 (2015): 201–8. https://doi.org/10.11648/j.ejpm.20150306.18.

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Serratia marcescens (S. marcescens) has become an important nosocomial pathogens and increased resistant isolates were reported. The current study evaluates the impact of an alternate energy medicine i.e. Mr. Trivedi’s biofield energy treatment on S. marcescens for changes in sensitivity pattern of antimicrobial, biochemical characteristics, and biotype number. S. marcescens cells were procured from MicroBioLogics Inc., USA in sealed pack bearing the American Type Culture Collection (ATCC 13880) number and divided into two groups, Group (Gr.) I: control and Gr. II: treated. Gr. II was fu

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Mayank Gangwar, and Snehasis Jana. "Assessment of Antibiogram of Biofield Energy Treated Serratia marcescens." European Journal of Preventive Medicine 3, no. 6 (2015): 201–8. https://doi.org/10.5281/zenodo.192898.

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Serratia marcescens (S. marcescens) has become an important nosocomial pathogens and increased resistant isolates were reported. The current study evaluates the impact of an alternate energy medicine i.e. Mr. Trivedi’s biofield energy treatment on S. marcescens for changes in sensitivity pattern of antimicrobial, biochemical characteristics, and biotype number. S. marcescens cells were procured from MicroBioLogics Inc., USA in sealed pack bearing the American Type Culture Collection (ATCC 13880) number and divided into two groups, Group (Gr.) I: control

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Álvaro, Bustos González, Ortiz Girón José, Diaz Cornejo Nohra, Galván Garces Olga, and Ruiz Garcés Luis. "Resistance profiles of bacterial pathogens isolated in a hospital institution in Montería - Córdoba, 2018." Indian Journal of Science and Technology 13, no. 46 (2020): 4564–72. https://doi.org/10.17485/IJST/v13i46.1897.

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Abstract <strong>Objective:</strong> To determine the resistance profiles of bacterial pathogens isolated in a hospital institution in Montería – Córdoba. <strong>Methodology:</strong> An observational study was carried out, during the months of January to December 2018; 344 samples were evaluated. Mention about the source of study samples. The identification and susceptibility of the bacteria were determined through the VITEK system. <strong>Findings:</strong> Among the Gram-negative bacteria identified were Klebsiella pneumoniae, Pseudomonas aerug

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N. Agrawal, Gopal, Neha S. Bawankar, Priyanka Kalbhor, Sunita Gajbhiye, and S. S. Zodpey (Shrikhande). "SERRATIA MARCESCENSBACTERAEMIA IN PRETERM NEONATE - A CASE REPORT." International Journal of Advanced Research 11, no. 01 (2023): 1658–61. http://dx.doi.org/10.21474/ijar01/16189.

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Background: Serratia marcescenshas emerged as opportunist in increasing number of hospital-associated infections in neonatal intensive care unit (NICUs), particularly as bloodstream infections. It is known to cause outbreaks in the NICUs, with high mortality rate in the vulnerable preterm population. Case presentation: We present a case of one and half month-old preterm neonate who had complaints of intolerance to feeding and failure to thrive. Clinical investigation revealed anaemia and increased inflammatory markers. Blood culture showed growth ofS marcescens.In antimicrobial susceptibility

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Cosimato, Ilaria, Biagio Santella, Sandra Rufolo, et al. "Current Epidemiological Status and Antibiotic Resistance Profile of Serratia marcescens." Antibiotics 13, no. 4 (2024): 323. http://dx.doi.org/10.3390/antibiotics13040323.

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The spread of antibiotic resistance represents a serious worldwide public health issue, underscoring the importance of epidemiology research in determining antimicrobial strategies. The purpose of this research was to investigate antibiotic resistance in Serratia marcescens isolates from clinical samples over seven years at the University Hospital “San Giovanni di Dio e Ruggi d’Aragona” in Salerno, Italy. S. marcescens is an important opportunistic pathogen associated with a wide spectrum of clinical diseases, including pneumonia, keratitis, meningitis, and urinary tract and wound infections.

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Darby, Andrea M., Destiny O. Okoro, Sophia Aredas, et al. "High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster." PLOS Pathogens 20, no. 8 (2024): e1012447. http://dx.doi.org/10.1371/journal.ppat.1012447.

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Overnutrition with dietary sugar can worsen infection outcomes in diverse organisms including insects and humans, through generally unknown mechanisms. In the present study, we show that adult Drosophila melanogaster fed high-sugar diets became more susceptible to infection by the Gram-negative bacteria Providencia rettgeri and Serratia marcescens. We found that P. rettgeri and S. marcescens proliferate more rapidly in D. melanogaster fed a high-sugar diet, resulting in increased probability of host death. D. melanogaster become hyperglycemic on the high-sugar diet, and we find evidence that t

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Ivanchenko, D. A., and L. M. Hrytsenko. "In vitro synergy testing of prodigiosin in combination with inhibitors of cell wall synthesis against Mycobacterium smegmatis." Regulatory Mechanisms in Biosystems 11, no. 1 (2020): 127–32. http://dx.doi.org/10.15421/022019.

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The cell wall is not a target of currently used therapeutics as Mycobacterium are considered naturally resistant to most β-lactam antibiotics. Therefore, combinations of conventional antibiotics with antibiotic activity-enhancing compounds offer a productive treatment strategy and address the widespread emergence of antibiotic-resistant strains. The first area of research was the study of a comparative analysis of disk diffusion testing and the broth dilution method for evaluating the susceptibility of M. smegmatis to antimicrobial agents. A comparative analysis of the susceptibility to antimi

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Zhong, Yuxia, Wanting Liu, Peibo Yuan, Ling Yang, Zhenbo Xu, and Dingqiang Chen. "Occurrence of Serratia marcescens Carrying blaIMP-26 and mcr-9 in Southern China: New Insights in the Evolution of Megaplasmid IMP-26." Antibiotics 11, no. 7 (2022): 869. http://dx.doi.org/10.3390/antibiotics11070869.

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The spread of multidrug-resistant enterobacteria strains has posed a significant concern in public health, especially when the strain harbors metallo-beta-lactamase (MBL)-encoding and mobilized colistin resistance (mcr) genes as such genetic components potentially mediate multidrug resistance. Here we report an IncHI2/2A plasmid carrying blaIMP-26 and mcr-9 in multidrug-resistant Serratia marcescens human isolates YL4. Antimicrobial susceptibility testing was performed by the broth microdilution method. According to the results, S. marcescens YL4 was resistant to several antimicrobials, includ

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Garza-González, Elvira, Sandra Iveth Mendoza Ibarra, Jorge M. Llaca-Díaz та Gloria M. Gonzalez. "Molecular characterization and antimicrobial susceptibility of extended-spectrum β-lactamase-producing Enterobacteriaceae isolates at a tertiary-care centre in Monterrey, Mexico". Journal of Medical Microbiology 60, № 1 (2011): 84–90. http://dx.doi.org/10.1099/jmm.0.022970-0.

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Our objective was to analyse phenotypic and genetic data of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae, Enterobacter cloacae, Escherichia coli and Serratia marcescens that cause infections in our hospital. Over a 3 year period, 342 randomly selected clinical Enterobacteriaceae isolates were tested for ESBL production and evaluated for the presence of the β-lactamase genes bla SHV, bla TEM, bla CTX-M and bla TLA-1. The antibiotic susceptibilities of these isolates were also determined, and the clonality of the isolates was assessed by PFGE. Based on our analyses, 33/92

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Jung, Ji-A., Aeran Kim, Byoung Joo Seo, et al. "Specific Detection of Serratia marcescens Based on a PCR Assay and Antimicrobial Susceptibility of S. marcescens Isolated from Boar Semen." Journal of Life Science 23, no. 9 (2013): 1133–39. http://dx.doi.org/10.5352/jls.2013.23.9.1133.

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Mulinganya, Guy M., Maud Claeys, Serge Z. Balolebwami, et al. "Etiology of Early-Onset Neonatal Sepsis and Antibiotic Resistance in Bukavu, Democratic Republic of the Congo." Clinical Infectious Diseases 73, no. 4 (2021): e976-e980. http://dx.doi.org/10.1093/cid/ciab114.

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Abstract Background The Democratic Republic of the Congo (DRC) has one of the highest neonatal death rates (between 14% and 28%) in the world. In the DRC, neonatal sepsis causes 15.6% of this mortality, but data on the bacterial etiology and associated drug susceptibility are lacking. Methods Hemocultures of 150 neonates with possible early-onset neonatal sepsis (pEOS) were obtained at the Hôpital Provincial Général de Référence de Bukavu (Bukavu, DRC). The newborns with pEOS received an empirical first-line antimicrobial treatment (ampicillin, cefotaxime, and gentamicin) based on the synopsis

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Wenzel, Richard P., Daniel F. Sahm, Clyde Thornsberry, Deborah C. Draghi, Mark E. Jones, and James A. Karlowsky. "In Vitro Susceptibilities of Gram-Negative Bacteria Isolated from Hospitalized Patients in Four European Countries, Canada, and the United States in 2000-2001 to Expanded-Spectrum Cephalosporins and Comparator Antimicrobials: Implications for Therapy." Antimicrobial Agents and Chemotherapy 47, no. 10 (2003): 3089–98. http://dx.doi.org/10.1128/aac.47.10.3089-3098.2003.

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ABSTRACT Access to current antimicrobial agent surveillance data is an important prerequisite for the optimal management of patients with hospital-acquired infections. The present study used data collected in 2000 to 2001 from 670 laboratories in Europe (France, Germany, Italy, and Spain), Canada, and the United States to report on the in vitro activities of ceftriaxone, cefotaxime, and comparative agents against >125,000 isolates of gram-negative bacteria from hospitalized patients. All but two isolates of Enterobacteriaceae (one isolate of Proteus mirabilis from France and one isolate of

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Shakurfow, Fathi Abdullah, Abdel-kareem Bashir Abdallah, Asma Ownallah Elgaed, Najia Khalid Altarhouni, Fatma Abd-Elsalam Alfaqih, and Osama Mohamed Shakurfo. "Distribution of Pathogenic Bacterial Causing Urinary Tract Infection and their Sensitivity and Resistant to Antibiotics." Libyan Journal of Medical Research 17, no. 1 (2023): 146–54. http://dx.doi.org/10.54361/ljmr.17-15.

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Background, Urinary tract infection is one of the common infections in the Libya community. Distribution and susceptibility of causing pathogens change rendering to period and place. UTI are difficult infections, because UTI sick of children, men and pregnant women. The aims of this study are determine the relationship between UTI and gender and age by determine the prevalence of UTI in children, men and women, and observe the more common pathogenic bacteria in UTI. Also, to determine the antimicrobial susceptibility of pathogenic bacteria. Study area, The data of the present article had taken

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Mohapi, Dineo Attela, Tsepo Ramatla, Oriel Thekisoe, Zenzile Peter Khetsha, and Jane Nkhebenyane. "Antimicrobial Resistance Profiles of Bacteria Isolated from Fresh Vegetables in Free State Province, South Africa." Foods 14, no. 12 (2025): 2139. https://doi.org/10.3390/foods14122139.

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The important role of antibiotics cannot be overestimated, as human health relies heavily on them for the treatment of infectious diseases. In this study, the antimicrobial susceptibility profiles of pathogens isolated from spinach (Spinacia oleracea) and cabbage (Brassica oleracea) collected from Free State Province were investigated. A total of 38 isolates representing 10 species, Enterobacter cloacae (5.3%), Staphylococcus aureus (13.2%), Micrococcus luteus (5.3%), Staphylococcus sciuri (5.3%), Acinetobacter haemolyticus (5.3%), Burkholderia cepacia (15.8%), Pseudomonas luteola (15.8%), Esc

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Abid, Suhad Abbas, Israa M. S. Al-Kadmy, Sarah Naji Aziz, and Israa H. Hamzah. "The predominance of virulence genes associated with multidrug-resistant Serratia marcescens isolated from urinary tract infections." Reviews and Research in Medical Microbiology 35, no. 3 (2023): 160–66. http://dx.doi.org/10.1097/mrm.0000000000000343.

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Purpose: Serratia marcescens owns different virulence factors that contribute to their pathogenesis and result in bacterial invasion and resistance. Moreover, patients who suffer from urinary tract infections (UTIs) are at an increased risk of contracting different bacterial infections. This study aimed to detect and verify the occurrence of virulence genes in S. marcescens isolated from patients with UTIs in some hospitals in Iraq. Methodology: After bacterial collection, the identification was achieved by busing phenotypic and genotypic methods. The antibiotic susceptibility patterns were do

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Tapia-Arreola, Ana K., Daniel A. Ruiz-Garcia, Hectorina Rodulfo, Ashutosh Sharma, and Marcos De Donato. "High Frequency of Antibiotic Resistance Genes (ARGs) in the Lerma River Basin, Mexico." International Journal of Environmental Research and Public Health 19, no. 21 (2022): 13988. http://dx.doi.org/10.3390/ijerph192113988.

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The spread of beta-lactamase-producing bacteria is of great concern and the environment has been found to be a main source of contamination. Herein, it was proposed to determine the frequency of antimicrobial-resistant-Gram-negative bacteria throughout the Lerma River basin using phenotypic and molecular methods. Resistant bacteria were isolated with chromogenic media and antimicrobial susceptibility tests were used to characterize their resistance. ARGs for beta-lactams, aminoglycosides, and quinolones were detected by PCR. Species were identified by Sanger sequencing the 16S rRNA gene and th

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Vásquez-García, Andrea, Thaysa dos Santos Silva, Sabrina R. de Almeida-Queiroz, et al. "Species identification and antimicrobial susceptibility profile of bacteria causing subclinical mastitis in buffalo." Pesquisa Veterinária Brasileira 37, no. 5 (2017): 447–52. http://dx.doi.org/10.1590/s0100-736x2017000500004.

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ABSTRACT: Microorganisms causing subclinical mastitis in water buffalo were isolated from 20 buffalo milk samples at four dairy farms located in central region of São Paulo State, Brazil, through testing of somatic cell count (SCC), standard plate count (SPC), biochemical, PCR assays and antimicrobial profile. The SCC showed average of 721,000 cells/mL in the milk, indicating the presence of subclinical mastitis. The overall average for SPC was 1.8 x 104 CFU/mL. The microorganism most frequently isolation according to biochemical tests were: Staphylococcus epidermidis (17%), Staphylococcus aur

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Mbehang Nguema, Pierre Philippe, Richard Onanga, Guy Roger Ndong Atome, et al. "High level of intrinsic phenotypic antimicrobial resistance in enterobacteria from terrestrial wildlife in Gabonese national parks." PLOS ONE 16, no. 10 (2021): e0257994. http://dx.doi.org/10.1371/journal.pone.0257994.

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Data on the prevalence of antibiotic resistance in Enterobacteriaceae in African wildlife are still relatively limited. The aim of this study was to estimate the prevalence of phenotypic intrinsic and acquired antimicrobial resistance of enterobacteria from several species of terrestrial wild mammals in national parks of Gabon. Colony culture and isolation were done using MacConkey agar. Isolates were identified using the VITEK 2 and MALDI-TOF methods. Antibiotic susceptibility was analysed and interpreted according to the European Committee on Antimicrobial Susceptibility Testing guidelines.

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Daniel, Sakyi Agyirifo, Abonyi Mensah Theophilus, Seyenam Yao Senya Andrews, Assan Meshach, and Plas Otwe Emmanuel. "Antimicrobial susceptibility and resistance genes profiles in gram negative isolates from automated teller machines in Cape Coast, Ghana." African Journal of Biological Sciences 4, no. 3 (2022): 92–102. https://doi.org/10.33472/AFJBS.4.3.2022.92-102.

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The prevalence and type of microorganisms present on surfaces is an important factor to consider in infection outbreaks. The study identified bacterial isolates from Automated Teller Machines (ATMs) and screened the isolates against antibiotics of aminoglycosides, penicillins, tetracyclines, and phenicols classes for efficacy. The isolates were further tested for presence of genes that encodes for aminoglycosides, tetracyclines, glycopeptides, penicillins, and betalactamases. The bacterial isolates were identified as clinical isolates of Enterobacteriaceae and Pseudomonadaceae and frequently c

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Kadoom, Aram, Daniel Lockhart, Yassar Kadoom, et al. "306. Rapid Detection Of Bloodstream Infections, Including Molecular Characterization, From Whole Blood." Open Forum Infectious Diseases 7, Supplement_1 (2020): S150—S151. http://dx.doi.org/10.1093/ofid/ofaa439.349.

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Abstract Background Diagnosis of bloodstream infections (BSI) and treatment with appropriate antimicrobials is dependent upon fast and accurate information about the microorganism(s). The long time taken for a blood culture result, microbial identification and antimicrobial susceptibility testing (AST), can lead to poor antimicrobial stewardship. Many antimicrobial change decisions are based on the results of a Gram stain, with this being the first result available. Having results from a rapid test, direct from blood, which can confirm BSI and characterize the causative pathogen(s) would provi

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Patel, Pooja, Chinmayi Joshi, and Vijay Kothari. "The Anti-infective Potential of Hydroalcoholic Extract of Phyllanthus emblica Seeds Against Selected Human-pathogenic Bacteria." Infectious Disorders - Drug Targets 20, no. 5 (2020): 672–92. http://dx.doi.org/10.2174/1871526519666190821154926.

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Introduction: In the context of the global threat of antimicrobial resistance (AMR) among bacterial pathogens against conventional bactericidal antibiotics, investigation on complementary/ alternative approaches to manage bacterial infections is warranted. The present study aimed at investigating the anti-pathogenic potential of Phyllanthus emblica seed extract (PESE) against four different pathogenic bacteria. Methods: Hydroalcoholic extract of P. emblica seeds was tested for its possible in vitro quorummodulatory potential against Chromobacterium violaceum, Serratia marcescens, Pseudomonas a

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Kosilova, I. S., L. V. Domotenko, N. K. Fursova, S. V. Dentovskaya, M. G. Ershova, and A. P. Shepelin. "TRIALS OF THE DOMESTICALLY PRODUCED NUTRIENT MEDIUM «AGAR MULLER-HINTON II - OBOLENSK»." Russian Clinical Laboratory Diagnostics 64, no. 6 (2019): 360–67. http://dx.doi.org/10.18821/0869-2084-2019-64-6-360-367.

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The results of the comparative tests of the «Agar Muller-Hinton II - Obolensk» nutrient medium developed in SRCAMB, Obolensk, and the control nutrient medium imported «Mueller Hinton II Agar» are presented in the study. The susceptibility of bacterial clinical strains to antimicrobial agents (AMP) was determined by the disc diffusion method and the method of gradient diffusion (E-test). The carbapenemase activity of the strains carrying the carbapenemase genes was determined by CIM-test. Total 173 characterized bacterial strains of species Klebsiella pneumoniae, Pseudomonas aeruginosa, Acineto

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Sader, Helio S., Michael D. Huband, Cecilia G. Carvalhaes, and Mariana Castanheira. "2217. Frequency and Antimicrobial Susceptibility of Bacteria Isolated from Patients Hospitalized with Pneumonia in US Medical Centers During 2018." Open Forum Infectious Diseases 6, Supplement_2 (2019): S756. http://dx.doi.org/10.1093/ofid/ofz360.1895.

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Abstract Background Rapidly introducing appropriate antimicrobial therapy is crucial to reduce morbidity and mortality of patients hospitalized with pneumonia (PHP), and therapy is determined mostly by understanding causative pathogens. Ceftazidime–avibactam (CAZ-AVI) was recently approved and ceftolozane–tazobactam (C-T) is in late-stage clinical development for treating nosocomial pneumonia, including ventilator-associated. Methods Bacterial isolates were consecutively collected from PHP (1/patient) in 67 US medical centers in 2018 and the Gram-negative bacilli (GNB) were tested by reference

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Kohira, Naoki, Joshua West, Akinobu Ito, et al. "In VitroAntimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains." Antimicrobial Agents and Chemotherapy 60, no. 2 (2015): 729–34. http://dx.doi.org/10.1128/aac.01695-15.

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ABSTRACTS-649266 is a novel siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. Two sets of clinical isolate collections were used to evaluate the antimicrobial activity of S-649266 againstEnterobacteriaceae. These sets included 617 global isolates collected between 2009 and 2011 and 233 β-lactamase-identified isolates, including 47 KPC-, 49 NDM-, 12 VIM-, and 8 IMP-producers. The MIC90values of S-649266 against the first set ofEscherichia coli,Klebsiella pneumoniae,Serratia marcescens,Citrobacter freundii,Enterobacter aerogenes, andEnterobacter cloacaeiso

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Krishnaveni, M. K., Anil Kumar Bilolikar, and Sister Mariyamma Thomas. "Potential Reservoirs of Nosocomial Pathogens in a Hospital: An Investigational Study." International Journal of Current Microbiology and Applied Sciences 12, no. 8 (2023): 267–74. http://dx.doi.org/10.20546/ijcmas.2023.1208.028.

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The transmission of nosocomial pathogens in a hospital is a serious and growing concern worldwide. Environmental reservoirs could be playing a larger role in transmission than was first realized. This study evaluated environmental surveillance for nosocomial pathogens isolated from patients with hospital acquired infections. All the samples collected from the patients and environment were inoculated onto Mac Conkey Agar and 5% Sheep Blood Agar. These culture media were incubated overnight for 37°C. The growths obtained on the culture media were further processed for identification and antimicr

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Castañeda-Méndez, Paulo, Maria Lorena Cabrera-Ruiz, Armando Barragán-Reyes, et al. "388. Epidemiologic and Microbiologic Characteristics of Hospital-acquired Infections in Patients with COVID-19 at Intensive Care Unit, Mexico City." Open Forum Infectious Diseases 8, Supplement_1 (2021): S296. http://dx.doi.org/10.1093/ofid/ofab466.589.

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Abstract Background Patients with severe SARS-CoV-2 infection are at high risk of complications due to the intensive care unit stay. Hospital-acquired infections (HAI) are one of the most common complication and cause of death in this group of patients, it is important to know the epidemiology and microbiology of this hospital-acquired infections in order to begin to the patients a proper empirical treatment. We describe the epidemiologic and microbiologic characteristics of HAI in patients with COVID-19 hospitalized at intensive care unit (ICU) in a tertiary level private hospital in Mexico C

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Vagge, Aldo, Filippo Lixi, Diego Ponzin, et al. "Characterization of Conjunctival Microflora and Antibiotic Sensitivity Patterns in Patients Undergoing Cataract Surgery." Microorganisms 13, no. 2 (2025): 227. https://doi.org/10.3390/microorganisms13020227.

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This study aims to characterize the conjunctival flora of patients scheduled for cataract surgery and determine the susceptibility profile of isolated bacteria to several commonly used topical antibiotics. Conjunctival swabs were taken from 44 consecutive patients (25 males, 19 females; mean age of 75.0 ± 12.6 years) who were scheduled for senile cataract surgery at two Italian centers before starting any prophylactic preoperative treatment. Swabs were processed for the detection of the microbial growth and for species identification. Selective culture media were used, and bacteria were identi

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Yona, Yusto J., Kauke B. Zimbwe, Miguela A. Caniza, Maysam Homsi, and Sheena Mukkada. "Surveillance on antimicrobial Resistance pattern of Third Generation Cephalosporins at the Benjamin Mkapa Tertiary Hospital in Tanzania." Journal of the Pediatric Infectious Diseases Society 13, Supplement_4 (2024): 17–18. http://dx.doi.org/10.1093/jpids/piae093.048.

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Abstract Background Antimicrobial resistance is a burden in Tanzania and the world economy, resulting in financial losses from lower production brought on by illness due to greater treatment expenses and death. Second- and third-line antibiotics like third generations of cephalosporins should be used rather than first-line, which is an expensive option, due to AMR. The direct effects of AMR include severe prolonged illnesses, prolonged hospital stays death, and (Global Action Plan on Antimicrobial Resistance., 2015) Methodology The retrospective study design was used to review AST to assess th

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Sader, H. S., M. Castanheira, J. M. Streit, C. G. Carvalhaes, and R. E. Mendes. "#9: Frequency and Antimicrobial Susceptibility of Gram-Negative Organisms Causing Bloodstream Infections in Pediatric Patients from United States (US) Medical Centers (2014–2018)." Journal of the Pediatric Infectious Diseases Society 10, Supplement_1 (2021): S5. http://dx.doi.org/10.1093/jpids/piaa170.015.

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Abstract Background Ceftazidime–avibactam is US FDA approved for the treatment of pneumonia and complicated intra-abdominal and urinary tract infections in adults, and it is in late-stage clinical development for the treatment of pediatric patients. Methods Organisms were consecutively collected from pediatric patients (≤17 years old) with bloodstream infections in 33 US medical centers in 2014–2018. Enterobacterales, P. aeruginosa, and H. influenzae isolates (n = 976) were susceptibility (S) tested against ceftazidime–avibactam and comparators by reference broth microdilution methods; 42.9% o

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HARADA, TETSUYA, MASUMI TAGUCHI, RYUJI KAWAHARA, MASASHI KANKI, and KENTARO KAWATSU. "Prevalence and Antimicrobial Susceptibility of Bacterial Pathogens in Ready-to-Eat Foods Retailed in Osaka Prefecture, Japan." Journal of Food Protection 81, no. 9 (2018): 1450–58. http://dx.doi.org/10.4315/0362-028x.jfp-18-035.

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ABSTRACT The potential human health risk of Japanese ready-to-eat (RTE) foods was investigated by determining the contamination by foodborne bacterial pathogens, the prevalence of opportunistic and nosocomial pathogens, and the antibiotic susceptibility of the isolates recovered from 96 samples of lightly pickled vegetables, 88 samples of Western-style desserts, and 98 samples of RTE fish and seafood products sold at retail in Osaka, Japan. Staphylococcus aureus, including isolates producing staphylococcal enterotoxin (SE), were isolated from six lightly pickled vegetable products, seven Weste

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Anueyiagu, Kenneth Nnamdi, Solomon Kadiya Audu, Bature Davou Joshua, Olorungbemi Elijah Pelumi, and Shehu Abdulazeez Haji. "Prevalence and antibiogram of coliform bacteria, and occurrence of fungi in subclinical mastitis in small ruminants in Plateau State, Nigeria." Journal of Animal Science and Veterinary Medicine 5, no. 3 (2020): 81–91. http://dx.doi.org/10.31248/jasvm2020.206.

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This study was conducted to determine the prevalence of coliform bacteria and fungi in ovine and caprine raw milk in Plateau State of Nigeria. In a cross sectional study, a total of 412 milk samples were collected aseptically and 206 questionnaires form where data such as breed, age, parity, lactation stage, floor type, and husbandry system were analyzed. Ewes and does without clinical mastitis were subjected to California Mastitis Test (CMT) to determine the presence of subclinical mastitis. Bacteriological assays and antibiotic susceptibility tests were performed according to standard guidel

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Ahmed, Dalia, Laith Yaaqoob, and Sehand Arif. "Biosynthesis of TiO2 nanoparticles using prodigiosin and evaluating its antibacterial activity against biofilm producing MDR- Acinetobacter baumannii." Al-Anbar Journal of Veterinary Sciences 13, no. 2 (2020): 137–51. http://dx.doi.org/10.37940/ajvs.2020.13.2.13.

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A rising number of hospital infections were caused by multi drug resistant A.baumannii. This microorganism has become a big global concern for clinicians. This study aimed to evaluate the antimicrobial activity of biosynthesized TiO2 nanoparticles against biofilm producing multi drug resistant A. baumannii. Bacteria were isolated from burn wounds. The selected isolate was identified using the routine biochemical assays, viteck 2, and confirmed by PCR technique, targeting the 16S rRNA and blaOXA-51 genes. Antimicrobial susceptibility tests were performed using Viteck 2 system and the biofilm pr

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Muñoz-Ibarra, Eleonora, Rafael A. Molina-López, Inma Durán, Biel Garcias, Marga Martín, and Laila Darwich. "Antimicrobial Resistance in Bacteria Isolated from Exotic Pets: The Situation in the Iberian Peninsula." Animals 12, no. 15 (2022): 1912. http://dx.doi.org/10.3390/ani12151912.

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Literature related to antimicrobial resistant (AMR) bacteria in exotic pets is minimal, being essential to report objective data on this topic, which represents a therapeutic challenge for veterinary medicine and public health. Between 2016 and 2020, laboratory records of 3156 exotic pet specimens’ microbiological diagnoses and antibiotic susceptibility testing (AST) results were examined. The samples were classified into three animal classes: birds (n = 412), mammalia (n = 2399), and reptilian (n = 345). The most prevalent bacteria in birds and mammals were Staphylococcus spp. (15% and 16%),

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Shamsheyeva, Alena, Niels Oppermann, Aimee Taku, et al. "2144. Performance of 2019 CLSI Ciprofloxacin Breakpoint Antimicrobial Susceptibility Testing Algorithms for Enterobacteriaceae and Pseudomonas aeruginosa Directly from Positive Blood Culture on the Accelerate Pheno™ System." Open Forum Infectious Diseases 6, Supplement_2 (2019): S726—S727. http://dx.doi.org/10.1093/ofid/ofz360.1824.

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Abstract Background The Clinical and Laboratory Standards Institute (CLSI) updated fluoroquinolone breakpoints in 2019 in response to evolving resistance and new outcome data. The performance of updated antimicrobial susceptibility testing (AST) algorithms for ciprofloxacin with the 2019 breakpoints for Enterobacteriaceae and Pseudomonas aeruginosa was evaluated using the Accelerate Pheno™ system with contrived positive blood culture samples compared with broth microdilution (BMD). Methods A total of 294 clinical isolates (100 P. aeruginosa, 82 Klebsiella spp., 56 E. coli, 24 Citrobacter spp.,

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Shortridge, Dee, Leonard R. Duncan, Michael A. Pfaller, and Robert K. Flamm. "Antimicrobial Activity of Ceftolozane–Tazobactam Tested against Contemporary (2012–2016) Enterobacteriaceae and Pseudomonas aeruginosa from ICU vs. non-ICU Isolates Collected in US Medical Centers." Open Forum Infectious Diseases 4, suppl_1 (2017): S366. http://dx.doi.org/10.1093/ofid/ofx163.894.

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Abstract Background Ceftolozane-tazobactam (C-T) is a combination of a novel antipseudomonal cephalosporin and a well-described β-lactamase inhibitor. C-T was approved by the United States (US) Food and Drug Administration in 2014 for complicated urinary tract infections, including acute pyelonephritis and complicated intra-abdominal infections. C-T is currently in clinical trials for the treatment of hospital-acquired pneumonia. The Program to Assess Ceftolozane-Tazobactam Susceptibility (PACTS) monitors C-T resistance to gram-negative (GN) isolates worldwide. This study compares the activiti

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Tomanić, Dragana, Biljana Božin, Nebojša Kladar, et al. "Environmental Bovine Mastitis Pathogens: Prevalence, Antimicrobial Susceptibility, and Sensitivity to Thymus vulgaris L., Thymus serpyllum L., and Origanum vulgare L. Essential Oils." Antibiotics 11, no. 8 (2022): 1077. http://dx.doi.org/10.3390/antibiotics11081077.

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Mastitis is considered to be one of the most important diseases of dairy cows in terms of health, production, and economy. Being the most common cause of antibiotic consumption in dairy cows, treatment of this disease is one of the biggest challenges in the veterinary profession as an increasing number of pathogens develop resistance to antibiotics used in the treatment. Therefore, new alternative approaches for limiting the use of antibiotics in livestock are required. For this reason, our study aimed to investigate prevalence of environmental mastitis associated bacterial strains, as well as

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Aidoo, N. B. "Bacterial Contamination of Donor Blood Units in a Ghanaian Blood Bank: A Critical Concern for Transfusion Safety." American Journal of Clinical Pathology 162, Supplement_1 (2024): S147—S148. http://dx.doi.org/10.1093/ajcp/aqae129.328.

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Abstract Introduction/Objective Background: Blood transfusions, while life-saving, pose a significant risk to patient safety, with transfusion-associated bacterial sepsis emerging as a persistent and potentially fatal threat. The prevalence and severity of bacterial contamination in donor blood units necessitate regular surveillance to ensure safe and effective transfusion therapy. Aim This study aimed to identify and assess the susceptibility of bacterial isolates in whole blood donor units at the blood bank of Cape Coast Teaching Hospital in the Central Region of Ghana. Methods/Case Report M

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Bilal Ahmad, Muhammad Saqib Ishaq, Qurban Ali, Muhammad Atif Khan, and Muhammad Ishfaq Khan. "MICROBIOLOGICAL ANALYSIS AND ANTIBIOTIC SUSCEPTIBILITY FOR SPONTANEOUS BACTERIAL PERITONITIS IN HOSPITALIZED PATIENTS WITH AND WITHOUT HEPATITIS C." JOURNAL OF MICROBIOLOGY AND MOLECULAR GENETICS 4, no. 3 (2023): 86–94. http://dx.doi.org/10.52700/jmmg.v4i3.137.

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In individuals with cirrhosis, spontaneous bacterial peritonitis (SBP) is a common and often fatal bacterial infection with ascites. The Pathological accumulation and collection of fluid in the peritoneal cavity is known as ascites. Ascites can be a challenging diagnosis. Individuals with or without underlying hepatitis C may have varying SBP. Antimicrobials are used to treat SBP, however because MDR organisms are present, initial empirical treatment may not be effective. The aim of the present study was to investigate the causative agents of ascites in SBP and to check antibiotic susceptibili

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Sader, Helio S., Cecilia G. Carvalhaes, Rodrigo E. Mendes, Mariana Castanheira, and Robert K. Flamm. "2214. Comparison of Cefepime–Zidebactam (WCK 5222), Ceftazidime–Avibactam, and Ceftolozane–Tazobactam Tested Against Gram-Negative Organisms Causing Pneumonia in United States Hospitals in 2018." Open Forum Infectious Diseases 6, Supplement_2 (2019): S755. http://dx.doi.org/10.1093/ofid/ofz360.1892.

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Abstract Background Zidebactam (ZID) is a bicyclo-acyl hydrazide antibiotic with a dual mechanism of action: selective Gram-negative PBP2 binding and β-lactamase inhibition. We evaluated the frequency and antimicrobial susceptibility (S) of Gram-negative bacilli (GNB) isolated from patients with pneumonia in US hospitals. Methods All 3,086 clinical isolates were consecutively collected from patients hospitalized with pneumonia (1/patient) in 29 US medical centers in 2018, and the GNB (n = 2,171) were S tested against cefepime (FEP)-ZID (1:1 ratio) and comparators by reference broth microdiluti

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Khalil, Nadim, Eleanor Powell, and Joel Mortensen. "663. Improved Detection of ESBL and AmpC Beta-Lactamase Producing Isolates of Enterobacteriaceae in Pediatric Patients with Bloodstream Infections Using Combined Genotypic and Phenotypic Antimicrobial Susceptibility Testing." Open Forum Infectious Diseases 7, Supplement_1 (2020): S387. http://dx.doi.org/10.1093/ofid/ofaa439.856.

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Abstract Background Infections secondary to pathogens resistant to third-generation cephalosporins (3GC), such as extended-spectrum (ESBL) and AmpC β-lactamase (AmpC) producing Enterobacteriaceae, are increasing. Currently, there are no recommendations regarding identification of AmpC in Citrobacter, Enterobacter, Morganella and Serratia spp. (CEMS organisms). This study’s aim was to increase the detection of AmpC and ESBL producing Enterobacteriaceae in blood cultures from pediatric population by combining genotypic with phenotypic antimicrobial susceptibility testing (AST). Methods All first

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Appel, Tobias M., Maria F. Mojica, Elsa De La Cadena, Christian Pallares, and Maria Virginia Villegas. "616. Evaluation of In Vitro Susceptibility to Ceftazidime/Avibactam of Clinical Isolates of Carbapenem Nonsusceptible Gram-Negative Bacilli from Colombia." Open Forum Infectious Diseases 6, Supplement_2 (2019): S287. http://dx.doi.org/10.1093/ofid/ofz360.684.

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Abstract Background Ceftazidime/avibactam (CZA) is a combination of a third-generation cephalosporin and a diazabicyclooctane β-lactamase inhibitor, which is active against a broad range of class A, C and D β-lactamases. In Colombia, high rates of multidrug-resistant Enterobacteriaceae (Ent)and P. aeruginosa (Pae) have been reported. Of special concern are KPC enzymes endemic in Ent and found in Pae, which are associated with higher mortality and healthcare costs, as well as limited therapeutic options. Herein, we evaluate the susceptibility of clinical isolates of carbapenem nonsusceptible En

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Castanheira, Mariana, Rodrigo E. Mendes, Leonard R. Duncan, Leah N. Woosley, and Robert K. Flamm. "Activity of Meropenem-Vaborbactam Against Enterobacteriaceae Isolates Carrying blaKPC Collected Worldwide." Open Forum Infectious Diseases 4, suppl_1 (2017): S377. http://dx.doi.org/10.1093/ofid/ofx163.930.

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Abstract Background Meropenem-vaborbactam (MER-VAB) is a carbapenem-β-lactamase inhibitor combination with enhanced activity against KPC-producing Enterobacteriaceae recently evaluated in a phase 3 clinical trials for cUTIs and infections due to CRE. We analyzed the activity of MER-VAB against 517 isolates carrying blaKPC collected worldwide during 2014–16. Methods Enterobacteriaceae isolates (n = 34,069) from 34 countries were susceptibility (S) tested by reference broth microdilution method for MER-VAB (at fixed 8 µg/mL) and comparators. Carbapenem-resistant Enterobacteriaceae (CRE; CLSI cri

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Sader, Helio S., Cecilia G. Carvalhaes, Rodrigo E. Mendes, Mariana Castanheira, and Mariana Castanheira. "200. Antimicrobial Activity of Ceftazidime-Avibactam and Comparators against AmpC Hyperproducing Enterobacterales and P. aeruginosa Collected from United States (US) Medical Centers (2016-2020)." Open Forum Infectious Diseases 8, Supplement_1 (2021): S122—S123. http://dx.doi.org/10.1093/ofid/ofab466.200.

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Abstract Background E. cloacae species complex (ECL), S. marcescens (SM), C. freundii species complex (CF), and P. aeruginosa (PSA) are common pathogens in a variety of clinical infections. These organisms can overexpress the chromosomal AmpC that encodes resistance to several β-lactams. We evaluated the activity of ceftazidime-avibactam (CAZ-AVI) and comparators against these organisms. Methods 17,650 isolates, including 4,400 ECL, 2,074 SM, 1,644 CF, and 9,532 PSA, were consecutively collected from 88 US medical centers in 2016-2020. Among these isolates, 3,127 were ceftazidime-nonsusceptibl

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Kumar, Ayush, and Elizabeth A. Worobec. "HasF, a TolC-homolog of Serratia marcescens, is involved in energy-dependent efflux." Canadian Journal of Microbiology 51, no. 6 (2005): 497–500. http://dx.doi.org/10.1139/w05-029.

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A tolC-like gene (hasF) was identified upon scanning the incomplete database of the S. marcescens genome. This gene was amplified using PCR and cloned in the pUC18 vector to yield pUCHF. Sequencing of the S. marcescens tolC-like hasF gene and subsequent amino acid sequence prediction revealed approximately 80% amino acid homology with the Escherichia coli TolC. A tolC-deficient strain of E. coli (BL923) containing pUCHF/hasF was analyzed for susceptibility to fluoroquinolones (ciprofloxacin, norfloxacin, and ofloxacin), chloramphenicol, sodium dodecyl sulfate (SDS), and ethidium bromide. Antib

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Piccirilli, Alessandra, Sabrina Cherubini, Fabrizia Brisdelli, et al. "Molecular Characterization by Whole-Genome Sequencing of Clinical and Environmental Serratia marcescens Strains Isolated during an Outbreak in a Neonatal Intensive Care Unit (NICU)." Diagnostics 12, no. 9 (2022): 2180. http://dx.doi.org/10.3390/diagnostics12092180.

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The whole-genome sequencing (WGS) of eighteen S. marcescens clinical strains isolated from 18 newborns hospitalized in the Neonatal Intensive Care Unit (NICU) at Pescara Public Hospital, Italy, was compared with that of S. marcescens isolated from cradles surfaces in the same ward. The identical antibiotic resistance genes (ARGs) and virulence factors were found in both clinical and environmental S. marcescens strains. The aac(6′)-Ic, tetA(41), blaSRT-3, adeFGH, rsmA, and PBP3 (D350N) genes were identified in all strains. The SRT-3 enzyme, which exhibited 10 amino acid substitutions with respe

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Parya, karbaschi Bahareh Rahimian Zarif *. and Zahra Houshmandi. "EVALUATION OF ANTIBACTERIAL EFFECT OF PRODIGIOSIN PIGMENT PRODUCED BY SERRATIA MARCESCENS AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI ISOLATED FROM PROCESSED FOOD." Indo American Journal of Pharmaceutical Sciences 04, no. 05 (2017): 1348–53. https://doi.org/10.5281/zenodo.804040.

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prodigiosin pigment is three Pyrrole that is secondary metabolite produced by some bacterial species like Serratia marcescens . prodigiosin activities and frequent drug shown to inhibit bacterial And has attracted the attention of many researchers in the field of medicine and pharmacy should be.The aim of this study was Evaluation of antibacterial effect of prodigiosin pigment produced by Serratia marcescens against Staphylococcus aureus and Escherichia coli isolated from processed food. Method:Standard strains of Serratia marcescens PTCC 1111 were prepared from collection of microbial strains

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Parente, Ticiana Mont Alverne Lopes, Emanuela de Lima Rebouças, Vitor Coutinho Vieira dos Santos, Francisco Cesar Barroso Barbosa, and Iriana Carla Junqueira Zanin. "Serratia marcescens resistance profile and its susceptibility to photodynamic antimicrobial chemotherapy." Photodiagnosis and Photodynamic Therapy 14 (June 2016): 185–90. http://dx.doi.org/10.1016/j.pdpdt.2016.04.007.

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Roy, Sayani, Jayalaxmi Wangkheimayum, Sanchari Choudhury, Bhaskar Das, Pranab Mazumder, and Amitabha Bhattacharjee. "Occurrence of virulent Serratia marcescens with co-existing antibiotic resistance determinants in ready-to-eat food samples." Journal of Microbiology and Infectious Diseases 13, no. 3 (2023): 118. http://dx.doi.org/10.5455/jmid.2023.v13.i3.3.

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Background: Foodborne illness is a global concern and identification of pathogens that cause foodborne disease is a public health priority. Serratia marcescens is an opportunistic pathogen responsible for food poisoning due to its ability to colonize the gastrointestinal surfaces. S. marcescens is also responsible for causing a wide range of extraintestinal infections like pneumonia, urinary tract infection, keratitis, etc. Aim: The current study investigated the presence of antibiotic resistant virulent S. marcescens from street food samples. Methods: Two pigmented S. marcescens were recovere

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Begic, Sanela, and Elizabeth A. Worobec. "Characterization of the Serratia marcescens SdeCDE multidrug efflux pump studied via gene knockout mutagenesis." Canadian Journal of Microbiology 54, no. 5 (2008): 411–16. http://dx.doi.org/10.1139/w08-019.

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Serratia marcescens is an important nosocomial agent having high antibiotic resistance. A major mechanism for S. marcescens antibiotic resistance is active efflux. To ascertain the substrate specificity of the S. marcescens SdeCDE efflux pump, we constructed pump gene deletion mutants. sdeCDE knockout strains showed no change in antibiotic susceptibility in comparison with the parental strains for any of the substrates, with the exception of novobiocin. In addition, novobiocin was the only antibiotic to be accumulated by sdeCDE-deficient strains. Based on the substrates used in our study, we c

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Singh, Gagandeep, Akanksha Singh Parihar, Vishakha Sharma, et al. "Evaluation of antibacterial activity of selected plant extracts against Serratia marcescens." Journal of Drug Research in Ayurvedic Sciences 9, no. 3 (2024): 166–72. http://dx.doi.org/10.4103/jdras.jdras_173_23.

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Abstract BACKGROUND: Serratia marcescens is a well-known Gram-negative, rod-shaped bacterium commonly found in soil, animal skin, hospital environment, and plant-based raw materials. It is an opportunistic pathogen that causes serious infections, including pneumonia, bloodstream infection, wound infection, meningitis, and respiratory and urinary tract infections. Due to multiple resistant strains of S. marcescens being identified, new and effective plant-based antimicrobial compounds/drugs against S. marcescens must be searched. The present study is focused to explore the Stem of Neem (Azadira

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