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1

Eaton, Simon. "The biochemical basis of antioxidant therapy in critical illness." Proceedings of the Nutrition Society 65, no. 3 (August 2006): 242–49. http://dx.doi.org/10.1079/pns2006501.

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During critical illness free radical production may increase as a result of, for example, sepsis or tissue trauma. In addition, because of a potential for increased losses, and the possibility of inadequate nutrition, the antioxidant defences of the body may become compromised. Thus, the delicate balance between free radicals and antioxidants may be disturbed. Various nutritional and pharmacological strategies to enhance antioxidant defences have been proposed, which aim either to maintain or enhance endogenous antioxidant stores or to provide alternative antioxidant agents. Trace elements and
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Viña, Jose, Mari-Carmen Gomez-Cabrera, and Consuelo Borras. "Fostering antioxidant defences: up-regulation of antioxidant genes or antioxidant supplementation?" British Journal of Nutrition 98, S1 (October 2007): S36—S40. http://dx.doi.org/10.1017/s0007114507839596.

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Vitamins have traditionally been considered as food components that are required in the normal diet to prevent deficiencies. However, a newer concept of the function of vitamins in nutrition has taken them beyond simply prevention of deficiency symptoms. This concept considers that many vitamins, when taken in relatively larges doses, have important functions beyond preventing deficiencies. Linus Pauling was instrumental in putting forward this concept, particularly for vitamin C. Thus, relatively high intakes of vitamins, and in particular vitamins C and E which are antioxidants, are consider
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Vanacker, H., J. Harbinson, J. Ruisch, T. L. W. Carver, and C. H. Foyer. "Antioxidant defences of the apoplast." Protoplasma 205, no. 1-4 (March 1998): 129–40. http://dx.doi.org/10.1007/bf01279303.

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Sevcikova, M., H. Modra, A. Slaninova, and Z. Svobodova. " Metals as a cause of oxidative stress in fish: a review." Veterinární Medicína 56, No. 11 (December 12, 2011): 537–46. http://dx.doi.org/10.17221/4272-vetmed.

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This review summarizes the current knowledge on the contribution of metals to the development of oxidative stress in fish. Metals are important inducers of oxidative stress in aquatic organisms, promoting formation of reactive oxygen species through two mechanisms. Redox active metals generate reactive oxygen species through redox cycling, while metals without redox potential impair antioxidant defences, especially that of thiol-containing antioxidants and enzymes. Elevated levels of reactive oxygen species lead to oxidative damage including lipid peroxidation, protein and DNA oxidation, and e
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Felicijan, Mateja, Metka Novak, Nada Kraševec, and Andreja Urbanek Krajnc. "Antioxidant defences of Norway spruce bark against bark beetles and its associated blue-stain fungus." Agricultura 12, no. 1-2 (December 1, 2015): 9–18. http://dx.doi.org/10.1515/agricultura-2016-0002.

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Abstract Bark beetles and their fungal associates are integral parts of forest ecosystems, the European spruce bark beetle (Ips typographus Linnaeus, 1758) and the associated pathogenic blue stain fungus Ceratocystis polonica (SIEM.) C. MOREAU, are the most devastating pests regarding Norway spruce [Picea abies (L.) H. KARST.]. Bark beetles commonly inhabit weakened and felled trees as well as vital trees. They cause physiological disorders in trees by destroying a phloem and cambium or interrupt the transpiration -ow in the xylem. Conifers have a wide range of effective defence mechanisms tha
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Chainy, Gagan Bihari Nityananda, Biswaranjan Paital, and Jagneswar Dandapat. "An Overview of Seasonal Changes in Oxidative Stress and Antioxidant Defence Parameters in Some Invertebrate and Vertebrate Species." Scientifica 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/6126570.

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Antioxidant defence system, a highly conserved biochemical mechanism, protects organisms from harmful effects of reactive oxygen species (ROS), a by-product of metabolism. Both invertebrates and vertebrates are unable to modify environmental physical factors such as photoperiod, temperature, salinity, humidity, oxygen content, and food availability as per their requirement. Therefore, they have evolved mechanisms to modulate their metabolic pathways to cope their physiology with changing environmental challenges for survival. Antioxidant defences are one of such biochemical mechanisms. At low
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Kusumaningrum, Amalia Ratna. "Antioxidant supplementation during in vitro maturation." Journal of Midwifery 4, no. 2 (June 7, 2020): 1. http://dx.doi.org/10.25077/jom.4.2.1-7.2019.

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During in vitro maturation (IVM), oocytes are exposed to different situations from in vivo which may cause oxidative stress. Supplementation of antioxidants to the culture media is effective in as antioxidant defences against reactive oxygen species (ROS). Antioxidant is safe, it has some side effects. This is reviewed in this paper. Studies reported, supplementation antioxidant with different dose showed different effects. Double-edged effects of exogenous antioxidants on cellular responses during in vitro maturation depending potentially on their concentrations. Physiologic doses leading to b
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8

Surai, Kochish, Fisinin, and Kidd. "Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update." Antioxidants 8, no. 7 (July 22, 2019): 235. http://dx.doi.org/10.3390/antiox8070235.

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Poultry in commercial settings are exposed to a range of stressors. A growing body of information clearly indicates that excess ROS/RNS production and oxidative stress are major detrimental consequences of the most common commercial stressors in poultry production. During evolution, antioxidant defence systems were developed in poultry to survive in an oxygenated atmosphere. They include a complex network of internally synthesised (e.g., antioxidant enzymes, (glutathione) GSH, (coenzyme Q) CoQ) and externally supplied (vitamin E, carotenoids, etc.) antioxidants. In fact, all antioxidants in th
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9

Lenaz, G., C. Bovina, G. Formiggini, and G. Parenti Castelli. "Mitochondria, oxidative stress, and antioxidant defences." Acta Biochimica Polonica 46, no. 1 (March 31, 1999): 1–21. http://dx.doi.org/10.18388/abp.1999_4179.

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Mitochondria are strongly involved in production of reactive oxygen species, considered today as the main pathogenic agent of many diseases. A vicious circle of oxidative stress and damage to cellular structures can lead to either cell death by apoptosis or to a cellular energetic decline and ageing. The early involvement of mitochondria in apoptosis includes expression of pro-apoptotic factors, release of cytochrome c from the inter-membrane space and opening of the permeability transition pore: cytochrome c release appears to precede pore opening. The mitochondrial theory of ageing considers
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10

Lenaz, Giorgio, Marika Cavazzoni, Maria Luisa Genova, Marilena D'Aurelio, Milena Merlo Pich, Francesco Pallotti, Gabriella Formiggini, Mario Marchetti, Giovanna Parenti Castelli, and Carla Bovina. "Oxidative stress, antioxidant defences and aging." BioFactors 8, no. 3-4 (1998): 195–204. http://dx.doi.org/10.1002/biof.5520080305.

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Colominas-Ciuró, R., M. Bertellotti, VL D’Amico, E. Carabajal, J. Benzal, V. Vidal, M. Motas, M. Santos, N. Coria, and A. Barbosa. "Diet, antioxidants and oxidative status in pygoscelid penguins." Marine Ecology Progress Series 665 (April 29, 2021): 201–16. http://dx.doi.org/10.3354/meps13651.

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Ecologically similar marine species inhabiting the same areas compete for food resources. Such competition is reduced by resource-partitioning strategies that may affect physiology. For instance, diet and feeding strategies may affect the antioxidant defences or the production of reactive oxygen species. Oxidative stress is defined as the imbalance between pro-oxidants and antioxidant defences. If such an imbalance favours the former, this can lead to oxidative damage, and oxidative stress increases. However, to our knowledge, how free-ranging animals adjust their oxidative status in relation
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12

Drury, Josephine A., Julie A. Nycyk, Malcolm Baines, and Richard W. I. Cooke. "Does Total Antioxidant Status Relate to Outcome in Very Preterm Infants?" Clinical Science 94, no. 2 (February 1, 1998): 197–201. http://dx.doi.org/10.1042/cs0940197.

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1. In healthy humans, a balance exists between oxygen-derived free-radical production and their removal by antioxidants. In preterm infants inadequate antioxidant defences may contribute to the pathogenesis of some of the complications of prematurity. 2. Plasma total antioxidant status and malondialdehyde concentration were measured during the first 11 days of life in 25 infants to determine whether increased lipid peroxidation is associated with low extracellular antioxidant status. In a second group of infants, total antioxidant status was quantified within 12 h of birth, and subsequently on
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13

Roveri, A., R. Bruni, A. Baritussio, M. Coassin, M. Benevento, M. Maiorino, and F. Ursini. "Antioxidant Defences of Rabbit Alveolar Lining Fluid." Respiration 55, no. 1 (1989): 68–73. http://dx.doi.org/10.1159/000195754.

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14

Filho, Danilo Wilhelm, Cecilia Giulivi, and Alberto Boveris. "Antioxidant defences in marine fish—I. Teleosts." Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 106, no. 2 (October 1993): 409–13. http://dx.doi.org/10.1016/0742-8413(93)90154-d.

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Filho, Danilo Wilhelm, and Alberto Boveris. "Antioxidant defences in marine fish—II. Elasmobranchs." Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 106, no. 2 (October 1993): 415–18. http://dx.doi.org/10.1016/0742-8413(93)90155-e.

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16

Gariballa, SE, and AJ Sinclair. "Cerebrovascular disease and oxidative stress." Reviews in Clinical Gerontology 9, no. 3 (August 1999): 197–206. http://dx.doi.org/10.1017/s0959259899009314.

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There is strong indirect evidence that free radical production appears to be an important mechanism of brain injury after exposure to ischaemia and reperfusion. Although significant brain damage occurs during an ischaemic episode, new cerebral damage can occur after reperfusion. One proposed mechanism for the brain damage that occurs during reperfusion involves generation of free radicals. Body defences against free radicals depends on the balance between free radical generation and the antioxidant protective defence system. Many of these protective antioxidants are essential nutrients or have
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17

Beaulieu, Michaël, Ines Bischofberger, Isabel Lorenz, Lucie Scheelen, and Klaus Fischer. "Reproducing butterflies do not increase intake of antioxidants when they could benefit from them." Biology Letters 12, no. 2 (February 2016): 20150941. http://dx.doi.org/10.1098/rsbl.2015.0941.

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The significance of dietary antioxidants may be limited by the ability of animals to exploit them. However, past studies have focused on the effects of dietary antioxidants after ‘antioxidant forced-feeding’, and have overlooked spontaneous antioxidant intake. Here, we found that reproducing female Bicyclus anynana butterflies had higher antioxidant defences and enhanced fecundity when forced to consume antioxidants (polyphenols). Interestingly, these positive effects were not constant across the oviposition period. When given the choice between food resources with and without antioxidants, re
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18

Fraternale, Daniele, Roberta De Bellis, Cinzia Calcabrini, Lucia Potenza, Luigi Cucchiarini, Umberto Mancini, Marina Dachà, and Donata Ricci. "Aqueous Extract from Vitis vinifera Tendrils is Able to Enrich Keratinocyte Antioxidant Defences." Natural Product Communications 6, no. 9 (September 2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600925.

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An aqueous extract of V. vinifera L. tendrils was evaluated for its ability to enrich the antioxidant capacity of cultured cells. The long-time antioxidant capability of the extract was measured by in vitro chemical methods, and its influence on reduced glutathione levels and plasma membrane oxido reductase activity was determined in cultured human keratinocytes (NCTC 2544). Keratinocytes are cells normally exposed to oxidative stress, and for this reason adequately equipped with antioxidant defences. However, it has long been suggested that exogenous antioxidants may play an important role in
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Gopalakrishnan, Singaram, Fang-Yi Chen, Harikrishnan Thilagam, Kun Qiao, Wan-Fang Xu, and Ke-Jian Wang. "Modulation and Interaction of Immune-Associated Parameters with Antioxidant in the Immunocytes of CrabScylla paramamosainChallenged with Lipopolysaccharides." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/824962.

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Invertebrates are dependent on cellular and humoral immune defences against microbial infection.Scylla paramamosainis an important commercial species, but the fundamental knowledge on its immune defense related to the antioxidant and immune-associated reactions is still lacking. The study was to differentiate the responses of immune-associated parameters of haemolymph components inS. paramamosainwhen challenged with bacterial lipopolysaccharides (LPSs). The immunostimulating effects of LPS in crab by triggering various immune parameters (phagocytosis, lysozyme, antibacterial activity, phenolox
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Rana, Mashidur, Sudhir C. Roy, and Bannur C. Divyashree. "Sperm antioxidant defences decrease during epididymal transit from caput to cauda in parallel with increases in epididymal fluid in the goat (Capra hircus)." Reproduction, Fertility and Development 29, no. 9 (2017): 1708. http://dx.doi.org/10.1071/rd16269.

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The status of antioxidant defences of both spermatozoa and their associated fluids during epididymal transit from the caput to cauda have not been studied so far in any species. Herein we report for the first time that sperm antioxidant defences, namely Cu,Zn-superoxide dismutase (Cu,Zn-SOD) and catalase activity, decrease significantly (P < 0.05) from the caput to cauda during epididymal transit in parallel with increases in Cu,Zn-SOD, total SOD and total glutathione peroxidase (GPx) activity in the luminal fluid of the respective segments. However, levels of GPX1 and GPX3 in epididymal fl
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Rajkumar S, Sambathkumar R, Gomathi Swaminathan, Vijayabaskaran M, and Kannan C. "Evaluation of Fluoride-Induced Neuro Degenerative Defences in Cyclea Peltata Lam Roots." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 21, 2020): 8034–41. http://dx.doi.org/10.26452/ijrps.v11i4.4756.

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Many diseases have become easier to diagnose and treat as a result of advancements in medical science and technology, but strokes, which have multiple etiologies and mechanisms, continue to be difficult to treat. Synthetic drugs are notorious for causing a slew of unavoidable side effects. Herbal drugs have a wide range of mechanisms of action and are typically free of side effects, making them excellent alternatives to synthetic drugs for stroke treatment. Cyclea peltata (Lam) Hook f. Thoms roots were studied for their neuroprotective properties against fluoride-induced neurodegeneration in r
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Fangyu, Wang, Yang Hongsheng Yang, Wang Xiaoyu, Xing Kun, and Gao Fei. "Antioxidant enzymes in sea cucumber Apostichopus japonicus (Selenka) during aestivation." Journal of the Marine Biological Association of the United Kingdom 91, no. 1 (July 5, 2010): 209–14. http://dx.doi.org/10.1017/s0025315410000779.

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To evaluate the effect of antioxidant defence in coelomic fluid of sea cucumber, Apostichopus japonicus in aestivation was studied in the field from July to November 2006 in Qingdao. During the sampling period, activities of superoxide dismutase and catalase increased significantly in August and November. Activities of glutathione reductase and glutathione decreased significantly in August and increased significantly in November and activities of Se-glutathione peroxidase increased significantly in August. There were no significant differences in total glutathione peroxidase. In relation to th
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Benavídes, María P., Patricia L. Marconi, Susana M. Gallego, María E. Comba, and María L. Tomaro. "Relationship between antioxidant defence systems and salt tolerance in Solanum tuberosum." Functional Plant Biology 27, no. 3 (2000): 273. http://dx.doi.org/10.1071/pp99138.

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A relationship between the antioxidant defence system and salt tolerance in two clones of potato (Solanum tuberosum L.) differing in salt sensitivity was studied. The antioxidant defence system of the sensitive clone responded differently to 100 and 150 mM NaCl. At 100 mM NaCl, growth, dehydroascorbate reductase and catalase activities remained unaltered, but chlorophyll and reduced glutathione content decreased (23% and 35%, respectively), while ascorbate content and superoxide dismutase activity were increased 34% and 63%, with respect to the control (0 mM NaCl). The superoxide dismutase inc
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Camus, Lionel, Bjørn Gulliksen, Michael H. Depledge, and Malcolm B. Jones. "Polar bivalves are characterized by high antioxidant defences." Polar Research 24, no. 1-2 (July 2005): 111–18. http://dx.doi.org/10.3402/polar.v24i1.6257.

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Fernandes, Ana Sofia, Matilde Castro, and Nuno Guerreiro Oliveira. "Oxidative stress and antioxidant defences – a pedagogical review." Journal Biomedical and Biopharmaceutical Research 8, no. 1 (June 2011): 97–108. http://dx.doi.org/10.19277/bbr.8.1.8.

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Frank, Lee. "Development of the antioxidant defences in fetal life." Seminars in Neonatology 3, no. 3 (August 1998): 173–82. http://dx.doi.org/10.1016/s1084-2756(98)80002-x.

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Camus, Lionel, Bjørn Gulliksen, Michael H. Depledge, and Malcolm B. Jones. "Polar bivalves are characterized by high antioxidant defences." Polar Research 24, no. 1-2 (July 2004): 111–18. http://dx.doi.org/10.1111/j.1751-8369.2004.tb00018.x.

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Camus, Lionel, Bjørn Gulliksen, Michael H. Depledge, and Malcolm B. Jones. "Polar bivalves are characterized by high antioxidant defences." Polar Research 24, no. 1-2 (July 2005): 111–18. http://dx.doi.org/10.1111/j.1751-8369.2005.tb00144.x.

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Tappia, Paramjit S., Kerry L. Troughton, Simon C. Langley-Evans, and Robert F. Grimble. "Cigarette Smoking Influences Cytokine Production and Antioxidant Defences." Clinical Science 88, no. 4 (April 1, 1995): 485–89. http://dx.doi.org/10.1042/cs0880485.

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1. Smoking exerts an inflammatory stimulus on lung macrophages, and smokers generally have low intakes of antioxidant micronutrients. This study was performed to investigate the relationship between whole-blood tumour necrosis factor production, plasma interleukin-6 and acute-phase protein concentration and antioxidant vitamins in smokers and non-smokers. 2. Measurement of tumour necrosis factor was conducted in whole blood stimulated with endotoxin (lipopolysaccharide), and interleukin-6 concentrations were measured in the plasma of smokers and non-smokers. Enzyme and dietary antioxidant conc
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Buffinton, Gary D., and William F. Doe. "Depleted mucosal antioxidant defences in inflammatory bowel disease." Free Radical Biology and Medicine 19, no. 6 (December 1995): 911–18. http://dx.doi.org/10.1016/0891-5849(95)94362-h.

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Bolton, Colin H., Alison A. Leaf, and Leonie G. Downs. "Antioxidant defences and lipid peroxidation in preterm infants." Biochemical Society Transactions 25, no. 3 (August 1, 1997): 522S. http://dx.doi.org/10.1042/bst025522s.

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Oso, Babatunde Joseph, Olufunke Temiloluwa Oso, and Adenike Temidayo Oladiji. "Redox balance: A probable target in the management of immune dysfunction." Brazilian Journal of Biological Sciences 5, no. 10 (2018): 259–64. http://dx.doi.org/10.21472/bjbs.051006.

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Activation of cell-mediated immune is usually interconnected with the generation of oxidative species. The objective of this review was to concisely discuss the interplay between redox balance and immune functions. A qualitative review of peer reviewed papers published in journals and other publications was conducted. The review showed that cellular oxidants which act as signalling molecules could drive biological responses such as those that modulate the productions of pro- and anti-inflammatory cytokines and immune function. Moreover, beneficial effects of these cellular oxidants could be ma
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Berzosa, C., I. Cebrián, L. Fuentes-Broto, E. Gómez-Trullén, E. Piedrafita, E. Martínez-Ballarín, L. López-Pingarrón, R. J. Reiter, and J. J. García. "Acute Exercise Increases Plasma Total Antioxidant Status and Antioxidant Enzyme Activities in Untrained Men." Journal of Biomedicine and Biotechnology 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/540458.

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Antioxidant defences are essential for cellular redox regulation. Since free-radical production may be enhanced by physical activity, herein, we evaluated the effect of acute exercise on total antioxidant status (TAS) and the plasma activities of catalase, glutathione reductase, glutathione peroxidase, and superoxide dismutase and its possible relation to oxidative stress resulting from exercise. Healthy untrained male subjects () performed three cycloergometric tests, including maximal and submaximal episodes. Venous blood samples were collected before and immediately after each different exe
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P, Sushma, Bindu Jacob, and Narendhirakannan R.T. "Evaluation Of Antioxidant And Cytotoxicity Properties Of Amygdalin Extracted From Prunus Dulcis." Kongunadu Research Journal 6, no. 2 (December 30, 2019): 8–12. http://dx.doi.org/10.26524/krj295.

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Free-radical reactions have been implicated in the pathology of many human diseases like atherosclerosis, ischemic heart disease, aging process, inflammation, diabetes, immuno-suppression,neurodegenerative disease etc. Radicals and other reactive oxygen species are formed constantly in the human body and are removed by the enzymatic and non-enzymatic antioxidant defence. The disturbance in ‘redox homeostasis’ that occurs when antioxidant defences are inadequate can damage lipids, proteins,carbohydrates and DNA. Drugs with multiple protective mechanisms, including antioxidant activity, may be o
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Mullineaux, Philip, Louise Ball, Carolina Escobar, Barbara Karpinska, Gary Creissen, and Stanislaw Karpinski. "Are diverse signalling pathways integrated in the regulation of Arabidopsis antioxidant defence gene expression in response to excess excitation energy?" Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 355, no. 1402 (October 29, 2000): 1531–40. http://dx.doi.org/10.1098/rstb.2000.0713.

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When low–light–grown Arabidopsis rosettes are partially exposed to excess light (EL), the unexposed leaves become acclimated to excess excitation energy (EEE) and consequent photo–oxidative stress. This phenomenon, termed systemic acquired acclimation (SAA), is associated with redox changes in the proximity of photosystem II, changes in foliar H 2 O 2 content and induction of antioxidant defences. The induction of extra–plastidial antioxidant systems is important in the protection of the chloroplast under EL conditions. A larger range of transcripts encoding different antioxidant defence enzym
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Marchioli, Roberto. "Vitamin E and Cardiovascular Disease." Thrombosis and Haemostasis 85, no. 05 (2001): 758–60. http://dx.doi.org/10.1055/s-0037-1615713.

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SummaryInterest in the use of antioxidants for the treatment of human disease, and in the role of dietary antioxidants in the prevention of disease development, has been sustained for at least two decades. Several anti-oxidant protective mechanisms exist and constitute a primary defensive system including enzymatic defences (glutathione peroxidase and superoxide dismutase, which depend on the presence of ions such as selenium, zinc, copper, and manganese) and naturally occurring vita-mins such as vitamin E, vitamin A, beta-carotene, and vitamin C. The most important natural antioxidants are vi
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Pablo Hernando, Marcelo, Gabriela Fabiana Malanga, and Gustavo Adolfo Ferreyra. "Oxidative stress and antioxidant defences generated by solar UV in a Subantarctic marine phytoflagellate." Scientia Marina 69, S2 (December 30, 2005): 287–95. http://dx.doi.org/10.3989/scimar.2005.69s2287.

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Babin, A., C. Saciat, M. Teixeira, J. P. Troussard, S. Motreuil, J. Moreau, and Y. Moret. "Limiting immunopathology: Interaction between carotenoids and enzymatic antioxidant defences." Developmental & Comparative Immunology 49, no. 2 (April 2015): 278–81. http://dx.doi.org/10.1016/j.dci.2014.12.007.

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Mougeot, Francois, Jesuús Martínez-Padilla, Lucy M. I. Webster, Jonathan D. Blount, Lorenzo Pérez-Rodríguez, and Stuart B. Piertney. "Honest sexual signalling mediated by parasite and testosterone effects on oxidative balance." Proceedings of the Royal Society B: Biological Sciences 276, no. 1659 (December 2, 2008): 1093–100. http://dx.doi.org/10.1098/rspb.2008.1570.

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Extravagant ornaments evolved to advertise their bearers' quality, the honesty of the signal being ensured by the cost paid to produce or maintain it. The oxidation handicap hypothesis (OHH) proposes that a main cost of testosterone-dependent ornamentation is oxidative stress, a condition whereby the production of reactive oxygen and nitrogen species (ROS/RNS) overwhelms the capacity of antioxidant defences. ROS/RNS are unstable, very reactive by-products of normal metabolic processes that can cause extensive damage to key biomolecules (cellular proteins, lipids and DNA). Oxidative stress has
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Wood, Lisa G., and Peter G. Gibson. "Reduced circulating antioxidant defences are associated with airway hyper-responsiveness, poor control and severe disease pattern in asthma." British Journal of Nutrition 103, no. 5 (October 29, 2009): 735–41. http://dx.doi.org/10.1017/s0007114509992376.

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Dietary antioxidants are important in protecting against oxidative stress. We have previously demonstrated that circulating dietary antioxidant levels are reduced in asthma. The present study examined the variation in dietary antioxidant levels in asthma, according to airway responsiveness, asthma control and clinical asthma pattern. Peripheral blood was collected from forty-one subjects with stable, persistent asthma. Airway responsiveness was assessed by hypertonic saline challenge. Asthma control was assessed using the Asthma Control Questionnaire. Clinical asthma pattern was determined usi
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Abdel Hamid, Enas R., Walaa H. Ali, Ashraf Azmy, Hanaa H. Ahmed, Lobna S. Sherif, and Maysa T. Saleh. "Oxidative Stress and Anti-Oxidant Markers in Premature Infants with Respiratory Distress Syndrome." Open Access Macedonian Journal of Medical Sciences 7, no. 17 (August 30, 2019): 2858–63. http://dx.doi.org/10.3889/oamjms.2019.534.

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BACKGROUND: Neonatal respiratory distress syndrome (RDS) caused by decreased surfactant and structural lung immaturity. The imbalance between oxidative status and antioxidant defence system was suggested to be an important trigger for lung affection with RDS.
 AIM: The goal of the current research was to elucidate the significance of the oxidant/ antioxidant status in the pathogenesis of RDS in preterm infants.
 PATIENTS AND METHODS: This controlled study included 31 preterm neonates with RDS and 36 healthy preterm neonates. Quantification level of oxidative stress biomarkers; malond
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Jiang, Jun, Xiao-Yun Wu, Xiao-Qiu Zhou, Lin Feng, Yang Liu, Wei-Dan Jiang, Pei Wu, and Ye Zhao. "Glutamate ameliorates copper-induced oxidative injury by regulating antioxidant defences in fish intestine." British Journal of Nutrition 116, no. 1 (May 17, 2016): 70–79. http://dx.doi.org/10.1017/s0007114516001732.

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AbstractThe objective of this study was to determine the protective effect of glutamate (Glu) in Cu-induced oxidative injury in fish intestine in vivo and enterocytes in vitro. The results indicated that exposure to 6 mg/l Cu for 72 h induced the production of reactive oxygen species, thereby increasing protein oxidation and lipid peroxidation in enterocytes of grass carp in vitro. Cells exposed to Cu alone resulted in a significant increase in lactate dehydrogenase release, which is accompanied by depletions of antioxidants, including total superoxide dismutase (T-SOD), glutathione S-transfer
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Fletcher, Louise A., Robert G. Fassett, Ross S. Richards, and Jeff S. Coombes. "Cyclosporine A induced changes to plasma and erythrocyte antioxidant defences." Redox Report 10, no. 1 (February 2005): 2–8. http://dx.doi.org/10.1179/135100005x21543.

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ITURBE-ORMAETXE, I., J. F. MORAN, C. ARRESE-IGOR, Y. GOGORCENA, R. V. KLUCAS, and M. BECANA. "Activated oxygen and antioxidant defences in iron-deficient pea plants." Plant, Cell and Environment 18, no. 4 (April 1995): 421–29. http://dx.doi.org/10.1111/j.1365-3040.1995.tb00376.x.

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Esserti, Siham, Amal Smaili, Kacem Makroum, Malika Belfaiza, Lalla Aicha Rifai, Tayeb Koussa, Imane Kasmi, and Mohamed Faize. "Priming of Nicotiana benthamiana antioxidant defences using brown seaweed extracts." Journal of Phytopathology 166, no. 2 (December 2, 2017): 86–94. http://dx.doi.org/10.1111/jph.12664.

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Song, Miryoung, Maroof Husain, Jessica Jones-Carson, Lin Liu, Calvin A. Henard, and Andrés Vázquez-Torres. "Low-molecular-weight thiol-dependent antioxidant and antinitrosative defences inSalmonellapathogenesis." Molecular Microbiology 87, no. 3 (December 21, 2012): 609–22. http://dx.doi.org/10.1111/mmi.12119.

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Cote, J., E. Arnoux, G. Sorci, M. Gaillard, and B. Faivre. "Age-dependent allocation of carotenoids to coloration versus antioxidant defences." Journal of Experimental Biology 213, no. 2 (December 28, 2009): 271–77. http://dx.doi.org/10.1242/jeb.035188.

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Carvalho, Félix, Eduarda Fernandes, Fernando Remião, and Maria Lourdes Bastos. "Effect of d -amphetamine repeated administration on rat antioxidant defences." Archives of Toxicology 73, no. 2 (April 21, 1999): 83–89. http://dx.doi.org/10.1007/s002040050591.

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Cheng, Lin, Pingnan Sun, Xiaoling Xie, Dongmei Sun, Qi Zhou, Shaozhe Yang, Qingdong Xie, and Xiaoling Zhou. "Hepatitis B virus surface protein induces oxidative stress by increasing peroxides and inhibiting antioxidant defences in human spermatozoa." Reproduction, Fertility and Development 32, no. 14 (2020): 1180. http://dx.doi.org/10.1071/rd20130.

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Hepatitis B virus (HBV) infection may affect sperm motility in patients with HBV. HBV surface protein (HBs) decreases mitochondrial membrane potential, impairs motility and induces apoptotic-like changes in human spermatozoa. However, little is known about how human spermatozoa respond to reactive oxygen species (ROS; mainly peroxides) induced by HBs. In this study, HBs induced supraphysiological ROS levels in human spermatozoa and reduced the formation of 2-cell embryos (obtained from hamster oocytes and human spermatozoa). HBs induced a pre-apoptotic status in human spermatozoa, as well as a
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Grundman, Michael, and Patrick Delaney. "Antioxidant strategies for Alzheimer's disease." Proceedings of the Nutrition Society 61, no. 2 (May 2002): 191–202. http://dx.doi.org/10.1079/pns2002146.

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Oxidative damage is present within the brains of patients with Alzheimer's disease (AD), and is observed within every class of biomolecule, including nucleic acids, proteins, lipids and carbohydrates. Oxidative injury may develop secondary to excessive oxidative stress resulting from β-amyloid-induced free radicals, mitochondrial abnormalities, inadequate energy supply, inflammation or altered antioxidant defences. Treatment with antioxidants is a promising approach for slowing disease progression to the extent that oxidative damage may be responsible for the cognitive and functional decline o
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