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Rozprawy doktorskie na temat „Aortic valve stenosis (AVS)”

Autor: Grafiati

Data publikacji: 9 listopada 2024

Data aktualizacji: 31 lipca 2025

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1

Ma, Qixiang. "Deep learning based segmentation and detection of aorta structures in CT images involving fully and weakly supervised learning." Electronic Thesis or Diss., Université de Rennes (2023-....), 2024. http://www.theses.fr/2024URENS029.

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La réparation endovasculaire des anévrismes aortiques abdominaux (EVAR) et l’implantation valvulaire aortique transcathéter (TAVI) sont des interventions endovasculaires pour lesquelles l’analyse des images CT préopératoires est une étape préalable au planning et au guidage de navigation. Dans le cas de la procédure EVAR, les travaux se concentrent spécifiquement sur la question difficile de la segmentation de l’aorte dans l’imagerie CT acquise sans produit de contraste (NCCT), non encore résolue. Dans le cas de la procédure TAVI, ils abordent la détection des repères anatomiques permettant de

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Lopez, Marco Ana. "Low-flow low-gradient aortic stenosis: outcomes after aortic valve replacement." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/667817.

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Aortic stenosis is the commonest valve disorder in the Western World. The natural history of the disease is very well described; with a decreased survival once symptoms occur. There is currently, no medical therapy available to reduce the natural progression of the aortic stenosis, and therefore, aortic valve replacement has been recognised as the standard of care treatment for symptomatic aortic stenosis, with TAVI having merged as alternative for those cases with high/prohibitive surgical risk. All types of aortic stenosis have in common a reduced valve area (AVA <1.0cm2), but depending o

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Paul, Anup K. "Assessment of the Severity of Aortic Stenosis using Aortic Valve Coefficient." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1470672658.

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Rubino, A. S. (Antonino S. ). "Efficacy of the Perceval sutureless aortic valve bioprosthesis in the treatment of aortic valve stenosis." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526212289.

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Abstract Aortic valve stenosis (AS) is one of the most diffuse valvular diseases in developed countries. AS is a progressive disease, which usually results in serious life-threatening adverse events. Defining a treatment strategy for AS is a focus of cardiovascular research, although the topic is still controversial because of its related clinical and economical implications. Surgical aortic valve replacement (AVR),which is regarded as the gold standard for the treatment of severe symptomatic AS, affords excellent results, particularly in asymptomatic patients with good functional status. AVR

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5

Peltonen, T. (Tuomas). "Endothelial factors in the pathogenesis of aortic valve stenosis." Doctoral thesis, University of Oulu, 2008. http://urn.fi/urn:isbn:9789514289880.

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Abstract Calcified aortic valve disease represents a spectrum of disease spanning from mild aortic valve sclerosis to severe aortic valve stenosis (AS), being an actively regulated disease process and showing some hallmarks of atherosclerosis. The calcified aortic valve lesion develops endothelial injury and is characterized by inflammation, lipid accumulation, renin-angiotensin system activation and fibrosis. There is no approved pharmacological treatment available in AS. This study was aimed to characterize gene expression of endothelial factors in aortic valves in patients representing

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6

MOSCHETTA, DONATO. "UNRAVELLING SEX-DEPENDENT MECHANISMS IN CALCIFIC AORTIC VALVE STENOSIS." Doctoral thesis, Università degli Studi di Milano, 2022. https://hdl.handle.net/2434/947275.

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Calcific aortic valve stenosis (CAVS) is the most common form of heart valve disease and affects about 3% of the population. Its prevalence increases with age, without a causal relation between ageing and CAVS development. To date, CAVS is a slow, progressive, multifactorial disorder considered to be actively driven by several cellular and molecular processes. Its natural history consists of a long clinically silent phase of non-uniform leaflet thickening with or without minimal calcification, known as aortic valve sclerosis (AVSc), without significant obstruction of blood flow, followed by th

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7

Pawade, Tania Ashwinikumar. "Imaging calcification in aortic stenosis." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29589.

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BACKGROUND Aortic stenosis is a common and potentially fatal condition in which fibro-calcific changes within the valve leaflets lead to the obstruction of blood flow. Severe symptomatic stenosis is an indication for aortic valve replacement and timely referral is essential to prevent adverse clinical events. Calcification is believed to represent the central process driving disease progression. 18F-Fluoride positron emission tomography computed tomography (PET-CT) and CT aortic valve calcium scoring (CT-AVC) quantify calcification activity and burden respectively. The overarching aim of this

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8

Zhao, Ying. "Effect of valve replacement for aortic stenosis on ventricular function." Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-46809.

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Background：Aortic stenosis (AS) is the commonest valve disease in the West. Aortic valve replacement (AVR) remains the only available management for AS and results in improved symptoms and recovery of ventricular functions. In addition, it is well known that AVR results in disruption of LV function mainly in the form of reversal of septal motion as well as depression of right ventricular (RV) systolic function. The aim of this thesis was to study, in detail, the early and mid-term response of ventricular function to AVR procedures (surgical and TAVI) as well as post operative patients’ exercis

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9

Bagur, Rodrigo Hernan. "Transcatheter aortic valve implantation for the treatment of patients with severe symptomatic aortic stenosis." Thesis, Université Laval, 2012. http://www.theses.ulaval.ca/2012/29420/29420.pdf.

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Fairbairn, Tim. "Severe aortic valve stenosis and the consequences of transcatheter and surgical aortic valve replacement : a cardiovascular magnetic resonance study." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/5853/.

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Background: Severe symptomatic aortic stenosis (AS) heralds a poor prognostic outlook and significant co-morbidity, with valve replacement the only definitive cure. Transcatheter aortic valve implantation (TAVI) has developed as an alternative to the standard treatment of surgical aortic valve replacement (SAVR) in high-risk or inoperable AS patients. The clinical and cost effectiveness of TAVI compared to SAVR requires further investigation. Methods: A prospective study of sixty seven TAVI and twenty seven SAVR patients, recruited from September 2009 to September 2011. Baseline assessments in

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11

Taniguchi, Tomohiko. "Initial Surgical VersusConservative Strategies in Patients With Asymptomatic Severe Aortic Stenosis." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225456.

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12

Kanamori, Norio. "Prognostic Impact of Aortic Valve Area in Conservatively Managed Patients With Asymptomatic Severe Aortic Stenosis With Preserved Ejection Fraction." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263349.

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13

Ahlén, Caroline. "Outcome of patients with severe aortic stenosis – A retrospective follow-up study." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9372.

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<p>Aortic stenosis is the most common valvular disease in the adult population. A significant aortic stenosis is a serious condition, and if a symptomatic patient is not operated on, it may in most cases cause death. We have examined how many aortic stenoses that were diagnosed during one year, and a follow-up of the patients was also performed. We found 77 patients with significant aortic stenosis with a mean age of 76±13 years. At the time of follow-up 30 (39%) patients, aged between 29-85 years, had been surgically treated with implantation of a valve prosthesis within 2-23 months after the

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14

Musa, Tarique Al. "Transcatheter and surgical aortic valve replacement for severe aortic stenosis : insights from cardiovascular magnetic resonance imaging." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/15238/.

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Background: Surgical aortic valve replacement (SAVR) remains first-line treatment for symptomatic severe aortic stenosis, whereas transcatheter aortic valve implantation (TAVI) is indicated in patients who are inoperable or considered too high-risk for surgery. Current focus is centred on differences in the impact of valve replacement upon cardiovascular function to guide patient selection and the development of novel prosthetic valves to improve outcomes. Cardiovascular Magnetic Resonance (CMR) imaging is the investigative modality of choice for such a purpose. Objectives: To compare the impa

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15

Bordoni, Barbara <1980&gt. "Balloon Aortic Valvuloplasty as Bridge-to-Decision in High Risk Patients with Severe Aortic Valve Stenosis." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6892/1/Tesi_def_270315_3.pdf.

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Background. A sizable group of patients with symptomatic aortic stenosis (AS) can undergo neither surgical aortic valve replacement (AVR) nor transcatheter aortic valve implantation (TAVI) because of clinical contraindications. The aim of this study was to assess the potential role of balloon aortic valvuloplasty (BAV) as a “bridge-to-decision” in selected patients with severe AS and potentially reversible contraindications to definitive treatment. Methods. We retrospectively enrolled 645 patients who underwent first BAV at our Institution between July 2007 and December 2012. Of these, the

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Bordoni, Barbara <1980&gt. "Balloon Aortic Valvuloplasty as Bridge-to-Decision in High Risk Patients with Severe Aortic Valve Stenosis." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6892/.

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Background. A sizable group of patients with symptomatic aortic stenosis (AS) can undergo neither surgical aortic valve replacement (AVR) nor transcatheter aortic valve implantation (TAVI) because of clinical contraindications. The aim of this study was to assess the potential role of balloon aortic valvuloplasty (BAV) as a “bridge-to-decision” in selected patients with severe AS and potentially reversible contraindications to definitive treatment. Methods. We retrospectively enrolled 645 patients who underwent first BAV at our Institution between July 2007 and December 2012. Of these, the

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17

Ding, Wenhong. "Survival and functional recovery following valve replacement in patients with severe aortic stenosis." Doctoral thesis, Umeå universitet, Medicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-82644.

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Background: Aortic stenosis (AS) is the most common heart valve disease in Europe and North America. Age-related calcification of the valve is the commonest cause of acquired AS, especially in patients older than 70 years.Conventional surgical aortic valve replacement (SAVR) and the novel, minimally invasive transcatheter aortic valve implantation (TAVI), effectively preserve left ventricular (LV) function, relieve symptoms and improve survival in patients with severe symptomatic AS. However, patients with impaired LV function may carry significant operative risk, and long recovery time. In ad

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18

Hagen-Peter, Gayle Ann. "Living with Aortic Stenosis: A Phenomenological Study of Patients' Experiences and Subsequent Health Choices." ScholarWorks @ UVM, 2015. http://scholarworks.uvm.edu/graddis/516.

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Symptomatic aortic stenosis (AS) is an increasing phenomenon as more adults live longer. The gold standard for treating AS is surgical aortic valve replacement (SAVR). Frequently, as older individuals with AS often have multiple comorbidities, a SAVR is determined to be too high risk. Therefore, a less invasive treatment option is available, namely a transcatheter aortic valve implantation (TAVI) or transcatheter aortic valve replacement (TAVR). Such biomedical procedures have encouraged life extension and the decision to intervene commonplace with the aging population. Without an intervention

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Näpänkangas, J. (Juha). "Pathogenesis of calcific aortic valve disease." Doctoral thesis, Oulun yliopisto, 2019. http://urn.fi/urn:isbn:9789526223520.

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Abstract Calcific aortic valve disease (CAVD) represents a disease spectrum, ranging from mild aortic valve sclerosis to severe obstructive aortic stenosis (AS), associated with a high risk of myocardial infarction and cardiovascular death. It is a common disease in the Western countries, and with their aging populations, its prevalence is likely to increase. Today, CAVD is recognized as an actively regulated disease. Mechanical stress and endothelial injury are the initiating factors, followed by lipid accumulation and oxidation, leading to inflammation, fibrosis and calcification. Ultimately

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Poggio, P. "THE ROLE OF VALVE INTERSTITIAL CELLS IN THE PATHOGENESIS OF CALCIFIC AORTIC VALVE DISEASE." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/229415.

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Calcific aortic valve disease (CAVD) is the most common etiology of acquired aortic valve disease. The early stage is characterized by thickening of the leaflets and none or marginal effect on the mechanical properties of the valve, while the end stage disease is associated with impaired leaflet motion and resistances to blood flow. These conditions are known as aortic valve sclerosis (AVSc) and calcific aortic valve stenosis (AVS), respectively. AVSc is present in 25–30% of patients over 65 years of age and in up to 40% of those over 75 years of age. Moreover, since AVSc hemodynamics are comp

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21

Ohukainen, P. (Pauli). "Molecular profiling of calcific aortic valve disease." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526211909.

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Abstract Calcific aortic valve disease (CAVD) is the most common valvular heart disease in the Western world. Although it shares mainly the same risk factors as coronary heart disease (CHD), i.e. similar initial events in both diseases but with time, they lead to different clinical outcomes. Thus, when it affects the coronary arteries, the disease leads to an obstructive or rupture-prone plaque whereas in the aortic valve, it causes massive calcification and ossification. This obstructs the blood flow from the left cardiac ventricle, causing myocardial hypertrophy, and if left untreated, heart

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Wang, Qian. "Patient-specific finite element modeling of biomechanical interaction in transcatheter aortic valve implantation." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54849.

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Transcatheter aortic valve implantation (TAVI) is an effective alternative treatment option for patients with severe aortic stenosis, who are at a high risk for conventional surgical aortic valve replacement or considered inoperable. Despite the short- and mid-term survival benefits of TAVI, adverse clinical events, such as paravalvular leak, aortic rupture, and coronary occlusion, have been reported extensively. Many of these adverse events can be explained from the biomechanics perspective. Therefore, an in-depth understanding of biomechanical interaction between the device and native tissue

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23

Nyström-Rosander, Christina. "Chlamydia pneumoniae in aortic valve sclerosis and thoracic aortic disease : aspects of pathogenesis and therapy /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5356-2/.

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Miyake, Makoto. "Early Surgery vs. Surgery After Watchful Waiting for Asymptomatic Severe Aortic Stenosis." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264637.

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Wallby, Lars. "Signs of inflammation in different types of heart valve disease : The VOCIN study." Doctoral thesis, Linköping : Department of Medical and Health Sciences, Linköping University, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11330.

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Muta, Eri. "Impact of the left ventricular mass index on the outcomes of severe aortic stenosis." Kyoto University, 2019. http://hdl.handle.net/2433/242385.

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DELLA, ROSA FRANCESCO. "Impact of asymptomatic carotid stenosis on mid term outcome of transcatheter aortic valve replacement." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2016. http://hdl.handle.net/10281/105574.

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Introduction Stroke is a potential major complication of aortic valve replacement (AVR), transcatheter aortic valve implantation (TAVI), and balloon aortic valvuloplasty (BAV). Although its occurrence is rare, stroke significantly affects survival and quality of life. Peripheral vascular disease and carotid artery disease are independent risk factors that have been identified as predictors of operative death according to surgical risk scores. The presence of a significant carotid stenosis may increase the surgical risk leading to the choice of a percutaneous transaortic valve implantation rath

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Heinrich, Russell Shawn. "Assessment of the fluid mechanics of aortic valve stenosis with in vitro modeling and control volume analysis." Diss., Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/16664.

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Dellgren, Göran. "Aortic valve replacement with stentless bioprostheses : prospective long-term studies of the Biocor and the Toronto SPV /." Stockholm : Karolinska institutet, 2002. http://diss.kib.ki.se/2002/91-7349-152-7.

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Van, Aswegen Karl. "Dynamic modelling of a stented aortic valve." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1747.

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Teien, Dag. "Assessment of aortic stenosis with special reference to Doppler ultrasound." Doctoral thesis, Umeå universitet, Klinisk fysiologi, 1986. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-103813.

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Ghotikar, Miheer S. "Aortic valve analysis and area prediction using bayesian modeling." [Tampa, Fla.] : University of South Florida, 2005. http://purl.fcla.edu/fcla/etd/SFE0001369.

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Simpson, Michael S. "An in vitro investigation of systolic anterior motion of the mitral valve." Thesis, Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/33615.

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Yap, Choon Hwai. "The fluid shear stress environment of the normal and congenital bicuspid aortic valve and the implications on valve calcification." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/45742.

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Calcific aortic valve disease is highly prevalent, especially in the elderly. Currently, the exact mechanism of the calcification process is not completely understood, limiting our ability to prevent or cure the disease. Ex vivo investigations, however, have provided evidence that the aortic valve's biological response is sensitive to mechanical forces, including fluid shear stresses, leading to the hypothesis that adverse fluid shear stress environment play a role in leading to valve calcification. This thesis seeks to investigate this hypothesis. A method for performing experimental measurem

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Holliday, Casey Jane. "Discovery of shear- and side-dependent messenger RNAs and microRNAs in aortic valvular endothelium." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/47517.

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Aortic valve (AV) disease is a major cause of cardiovascular-linked deaths globally. In addition, AV disease is a strong risk factor for additional cardiovascular events; however, the mechanism by which it initiates and progresses is not well-understood. We hypothesize that low and oscillatory flow is present on the fibrosa side of the AV and stimulates ECs to differentially regulate microRNA (miRNA) and mRNAs and influence AV disease progression. This hypothesis was tested employing both in vitro and in vivo approaches, high throughput microarray and pathway analyses, as well as a variety

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36

Alkhalil, Ahmad. "Outcomes Of Early Versus Late Discharge In Transfemoral Transcatheter Aortic Valve Replacement Via Minimally Invasive Strategy: A Propensity-Matched Analysis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1465592493.

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Olsson, Karin. "Hope and life-struggle : patients' experiences with Transcatheter Aortic Valve Implantation." Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-127873.

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The overall aim of this thesis is to explore experiences and self-reported outcomes from Transcatheter Aortic Valve Implantation, TAVI, among people with severe aortic stenosis. The thesis includes four studies. Study I-II are based on interviews performed the day before TAVI and Qualitative Concept Analysis was used for analysis. Study III is based on interviews at six months’ follow-up and Grounded Theory was used for analysis. Study IV is quantitative and based on questionnaires at baseline and at six months’ follow-up. Nonparametric, descriptive statistics were used for the analysis. Study

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Kumar, Anirudh. "SAFETY AND EFFICACY OF BALLOON AORTIC VALVULOPLASTY STRATIFIED BY ACUITY OF PATIENT ILLNESS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1623349720127583.

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Straiton, Nicola. "The acceptability of heart valve replacement procedures, and patient-reported outcomes in adults with aortic stenosis." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29843.

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The incidence of aortic stenosis (AS) is high and increasing alongside the aging of populations in developed countries. Yet the impact of severe AS and associated treatments on the lives of people and their carers who provide support, is poorly understood. This thesis aims to investigate patient-reported outcomes of severe AS and valve replacement for adults living with AS and the acceptability of these replacement procedures for individuals and their carers. A multi-method study was conducted, consisting of two systematic reviews one of which synthesised the evidence for functional ca

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Dobson, Laura Elizabeth. "Cardiovascular magnetic resonance imaging in severe aortic stenosis : impact of surgical and trans-catheter aortic valve replacement on reverse remodelling and fibrosis." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/12944/.

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Introduction: Aortic stenosis (AS) is the commonest valvular lesion in the developed world and is associated with adverse cardiac remodelling. With its excellent accuracy and reproducibility, cardiovascular magnetic resonance (CMR) imaging is an ideal tool to assess cardiac remodelling and reverse remodelling following surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI). The aims of this thesis were: 1) to evaluate gender differences in AS and following aortic valve replacement, 2) to evaluate the incidence of post-procedural myocardial infarction follow

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Vánky, Farkas. "Surgery for aortic stenosis : with special reference to myocardial metabolism, postoperative heart failure and long-term outcome /." Linköping : Linköpings universitet, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7471.

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D'Onofrio, Augusto. "Clinical and hemodynamic outcomes of trans-apical aortic valve implantation. insights from the i-ta registry." Doctoral thesis, Università degli studi di Padova, 2014. http://hdl.handle.net/11577/3423827.

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Senile degenerative calcific aortic valve stenosis (AVS) is a progressive disease characterized by a peculiar natural history. When symptoms begin (congestive heart failure and dyspnea, angina, syncope) mortality rate rapidly increase and quality of life dramatically worsen. It has been estimated that the overall survival of patients with severe symptomatic AVS is less than 50% 2 years after the onset of symptoms. The number of patients suffering from AVS worldwide will increase over time as life expectancy progressively extends. The treatment of choice for severe symptomatic AVS is aortic va

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De, Rui Marina. "Aortic valve replacement in elderly subjects: effects on physical performance, cognitive function and quality of life." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3425391.

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Background: aortic valve stenosis (AVS) is becoming more and more common in the elderly population, involving around 13.2% of subjects older than 75 years. In addition to worsening quality of life, untreated severe AVS has been associated with high short term mortality rate. However, these adverse outcomes could be modified by aortic valve replacement (AVR). In recent years, in particular, newer surgery procedures and anesthesiological techniques have allowed also older and frailer patients access to AVR procedures. Previous studies have evaluated the effectiveness of AVR in older subjects in

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Abessi, Ovais. "Leaflet Material Selection for Aortic Valve Repair." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/30191.

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Leaflet replacement in aortic valve repair (AVr) is associated with increased long-term repair failure. Hemodynamic performance and mechanical stress levels were investigated after porcine AVr with 5 types of clinically relevant replacement materials to ascertain which material(s) would be best suited for repair. Porcine aortic roots with intact aortic valves were placed in a left-heart simulator mounted with a high-speed camera for baseline valve assessment. Then, the non-coronary leaflet was excised and replaced with autologous porcine pericardium (APP), glutaraldehyde-fixed bovine pericard

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Madan, Ashish. "In vitro assessment of the effects of valvular stenosis on aorta hemodynamics and left ventricular function." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1527085221854915.

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Facchin, Michela. "Clinical and Hemodynamic Results after Transcatheter Aortic Valve implantation (TAVI): Early and Late (10-year) follow-up." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3424733.

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Transcatheter aortic valve implantation (TAVI) has become the treatment of choice in patients with severe symptomatic aortic stenosis (AS) considered inoperable or at high surgical risk. More recently, TAVI has been performed also to lower risk patients based on the Heart Team decision. Few studies have studied interaction between surgical risk categories and outcomes. Aim of the study To analyze safety and efficacy (VARC-2 defined) TAVI treated patients as function of different preoperative risk. To assess independent predictors of death. Methods Four-hundred-eighty-two patients who unde

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Bachlah, Dana Mohamad. "Modeling of the inner structural band of the aortic valve bio prosthesis." Bachelor's thesis, Igor Sikorsky Kyiv Polytechnic Institute, 2021. https://ela.kpi.ua/handle/123456789/43660.

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Обсяг дипломної роботи становить 73 сторінок, містить 28 ілюстрацій, 20 таблиць. Загалом опрацьовано 59 джерел. Актуальність: Захворювання аортального клапана призводять до серйозних дисфункцій, спричинених зворотним потоком клапана або підвищенням його опору. Наслідком цієї патології є важка серцева недостатність, скорочення тривалості та якість життя. Єдине лікування - хірургічна заміна клапана на штучний протез або пластику аортального клапана. Заміна хворого аортального клапана на штучний протез є ефективним методом профілактики серцевої недостатності, збільшення тривалості та поліпшення

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Conklin, Colleen. "Disparities in Survival and Mortality among Infants with Congenital Aortic, Pulmonary, and Tricuspid Valve Defects by Maternal Race/Ethnicity and Infant Sex." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3046.

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Background: The etiology of congenital heart valve defects is not well understood; little is known about the risk factors that contribute to the survival and mortality outcomes of children with these defects. Methods: Using data from the Texas Birth Defects Registry (TBDR) we conducted a retrospective cohort study of 2070 singleton infants with congenital aortic, pulmonary, or tricuspid valve atresia or stenosis born in Texas between January 1, 1996 and December 31, 2007 to Hispanic, Non-Hispanic (NH) black, and NH white women. TBDR data were death-to-birth matched by the Texas Vital Statistic

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Chaloupková, Aneta. "Farmakoekonomická analýza distribuce zdravotnického produktu CoreValve." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-113239.

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This diploma work is focused on using economic analysis methods to compare cost-effectivness of an innovative technology for treating aortic stenosis that is transcatheter implantation of an artificial valve CoreValve by Medtronic with traditional treatments. During the analyses we utilized only publicly available data which are often too general while more specific data might not be available because they do not exist or are not publicly available. This work sets up a theoretical foundation for the analyses, performs the analyse sof the product, PEST analyses and cost analyses. Since pacient'

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Pohjolainen, V. (Virva). "Characterization of non-collagenous extracellular matrix proteins in cardiac and aortic valve remodelling." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514299025.

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Abstract Heart failure (HF) and aortic valve stenosis (AS) are complex disorders affected by functional alterations and actively regulated remodelling of the heart and the aortic valve, respectively. In addition to structural proteins, such as collagens and elastin, the extracellular matrix (ECM) in the heart and the aortic valve comprises non-collagenous factors that are not strictly involved in the architecture but may modulate cardiac and valvular remodelling. In the present study the expression of non-collagenous fibrosis- and calcification-related ECM proteins was investigated in HF-assoc

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