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1

Arbiser, Jack L., Darlene Johnson, Cynthia Cohen, and Lawrence F. Brown. "High-Level Expression of Vascular Endothelial Growth Factor and its Receptors in an Aphthous Ulcer." Journal of Cutaneous Medicine and Surgery 7, no. 3 (2003): 225–28. http://dx.doi.org/10.1177/120347540300700306.

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Background: Aphthous ulcers are an extremely common disorder of unknown etiology. These ulcers cause significant morbidity through pain and interference with eating. Thalidomide, an angiogenesis inhibitor, is efficacious for the treatment of aphthous ulcers. Methods: In situ hybridization was performed on an idiopathic aphthous ulcer using probes specific for the angiogenesis factor vascular endothelial growth factor, and its receptors, in order to determine whether these ulcers are highly angiogenic. Conclusions: Aphthous ulcers are highly angiogenic. Thalidomide may act to heal aphthous ulce
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Vashishat, Bhart, Shruti Sinha, Tanmay Srivastava, et al. "Management of oral aphthous ulcer: A review." Bioinformation 20, no. 5 (2024): 434–38. http://dx.doi.org/10.6026/973206300200434.

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Aphthous ulcers, also known as canker sores, are a common oral condition characterized by recurrent, painful, small ulcers that typically arise on the non-keratinized mucous membranes within the mouth. Although the pathogenesis of aphthous ulcers is not completely understood; it is believed to be involved in a combination of genetic predisposition, local trauma, stress, hormonal changes, and certain environmental factors. Thus, management of aphthous ulcer revolves around reducing pain, promoting healing and preventing recurrence.
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Potra-Cicalău, G. I., I. Scrobotă, G. Iova, L. Todor, G. Ciavoi, and R. C. Iurcov. "Recurrent aphthous ulcers (RAU) and recurrent aphthous stomatitis (RAS) enigmatic etiopathology." Medicine in Evolution 29, no. 2 (2023): 136–41. http://dx.doi.org/10.70921/medev.v29i2.1011.

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Oral aphthous ulcer is a well-known condition that significantly affects the quality of life for patients by producing intense pain and difficulties in speaking and chewing. When recurrence is present we refer to them as recurrent aphthous ulcers (RAU) and recurrent aphthous stomatitis (RAS). Mouth ulcers are typically uncomfortable sores that can occur as a result of a variety of local and general disorders. It is one of the most prevalent oral ulcerative conditions.
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Prathoshini, Manthra. "Management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements." Bioinformation 16, no. 12 (2020): 992–98. http://dx.doi.org/10.6026/97320630016992.

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Recurrent Aphthous ulcers are the most common oral lesions among dental patients. The ulcers, which usually occur on the nonkeratinized oral mucosa, can cause considerable pain and may interfere with eating, speaking, and swallowing. Therefore, it is of interest to report data on the management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements. Case sheets of 76 patients who underwent treatment for recurrent aphthous ulcer between June 2019 and March 2020 at the Saveetha Dental College, India were used in this analysis. Data was analyzed using Chi
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Prathoshini, Manthra. "Management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements." Bioinformation 16, no. 12 (2020): 992–98. http://dx.doi.org/10.6026/97320630016992.

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Recurrent Aphthous ulcers are the most common oral lesions among dental patients. The ulcers, which usually occur on the nonkeratinized oral mucosa, can cause considerable pain and may interfere with eating, speaking, and swallowing. Therefore, it is of interest to report data on the management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements. Case sheets of 76 patients who underwent treatment for recurrent aphthous ulcer between June 2019 and March 2020 at the Saveetha Dental College, India were used in this analysis. Data was analyzed using Chi
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6

Lv, Xiaoying, and Yaxiong Guo. "Research Progress on Traditional Chinese Medicine Treatment of Recurrent Oral Ulcers in Children." Journal of Contemporary Medical Practice 7, no. 1 (2025): 197–200. https://doi.org/10.53469/jcmp.2025.07(01).37.

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Objective: To analyze and discuss the treatment of recurrent oral ulcers with traditional Chinese medicine (TCM), in order to provide a reference for the treatment of recurrent oral ulcers and other related oral diseases with TCM in the future. Methods: The key words “recurrent oral ulcers in children” or “recurrent aphthous ulcers in children” and the Chinese medical names “aphthous ulcers”, “aphthous ulcers”, “mouth ulcer”, “mouth erosion”, etc., and secondary searches with “Chinese medicine”, “combination of Chinese and Western medicine”, etc. were performed. A secondary search with “Chines
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7

Al-Bayati, Sura Ali Ahmed Fuoad. "A Case Report of Major Aphthous Ulcer." International Journal of Membrane Science and Technology 10, no. 2 (2023): 3390–95. http://dx.doi.org/10.15379/ijmst.v10i2.3124.

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Recurrent aphthous ulceration (RAU) is the most common ulcerative condition following traumatic ulcer that affects the oral cavity. It has three clinical presentations, major, minor and herpitiform aphthous ulceration, all are painful and mostly occur on non-keratinized mucosa. If not secondary infected it will heal spontaneously without leaving scar. Our patient was suffering from recurrent ulcers and one single large ulcer that prevent him from swallowing. Following a comprehensive history and clinical examination, interpreting the clinical findings, the ulcers had been diagnosed as aphthous
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8

Nzhad Mustafa, Bero, and Ali Fakhree Alzubaidee. "Comparative Evaluation of The Efficacy of Topical Hyaluronic Acid ( 0.2%) and Topical Triamcinolone Acetonide( 0.1%) in The Treatment of Recurrent Aphthous Stomatitis." Diyala Journal of Medicine 19, no. 2 (2020): 107–17. http://dx.doi.org/10.26505/djm.19025470628.

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Background: Recurrent aphthous ulcers are the most common oral lesion. They are classified into minor, major, and herpetiform ulcers. More than 85% of recurrent aphthous stomatitis presents as a minor ulcer. Hyaluronic acid is a biomaterial and it is a major carbohydrate component that can be found in many tissues and recently introduced as an alternative approach to enhance wound healing. Triamcinolone acetonide is a synthetic corticosteroid and it has two forms for topical use cream (0.1%) and ointment (0.1%). Objective: To make a comparison between the effectiveness of hyaluronic acid (0.2%
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9

Hamdy, Ahmed Abd El-Meguid Mostafa, and Mohamed Abd El-Moneam Ibrahem. "Management of Aphthous Ulceration with Topical Quercetin: A Randomized Clinical Trial." Journal of Contemporary Dental Practice 11, no. 4 (2010): 9–16. http://dx.doi.org/10.5005/jcdp-11-4-9.

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Abstract Aim Recurrent aphthous ulceration is the most commonly known oral mucosal disease. Quercetin is a useful therapeutic agent for the treatment of colitis and gastric ulcer. The objective of this study was to determine the effect of topical application of quercetin in the treatment of minor aphthous ulcers. Methods and Materials Forty male patients with no known pathology of the oral mucosa other than minor aphthous ulcers were enrolled in this study. Patients were randomly divided into two groups, each consisting of 20 patients. Group 1 (control group) patients used a benzydamine hydroc
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10

Bischoff, E. W. M. A., A. Uijen, and M. v. d. Wel. "Aphthous ulcers." BMJ 339, jul24 2 (2009): b2382. http://dx.doi.org/10.1136/bmj.b2382.

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11

Messadi, Diana V., and Fariba Younai. "Aphthous ulcers." Dermatologic Therapy 23, no. 3 (2010): 281–90. http://dx.doi.org/10.1111/j.1529-8019.2010.01324.x.

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12

Jain, Sulabh, Gayathri V. Nair, Sukanta K. Satapathy, and Rohan Shinkre. "The Role of Curcumin and Neem in the Form of Mouthwash in the Treatment of Aphthous Ulcer in the Oral Cavity." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 01 (2024): 313–15. http://dx.doi.org/10.25258/ijpqa.15.1.48.

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Background: Aphthous ulcers are common painful lesions that affect the oral mucosa. Traditional treatments often include topical agents to reduce inflammation and promote healing. Curcumin and neem are two natural compounds with known anti-inflammatory and antimicrobial properties, which may offer therapeutic benefits in the treatment of aphthous ulcers. Materials and Methods: Aphthous ulcers were the target of this research, which sought to determine if a mouthwash containing curcumin and neem was effective in treating them. About 100 people with aphthous ulcers were part in a randomized cont
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Susanto, Hendri, Rona Tirtaardi Dewi, and Mardiah Suci Hardianti. "Oral Aphthous-like Ulcers Response to Topical Therapy in Young Adult Woman with Beta-Thalassemia Intermedia." Journal of Indonesian Oral Medicine Society 2, no. 1 (2024): 8. http://dx.doi.org/10.32793/jioms.v2i1.1157.

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Background: Beta thalassemia may have some oral manifestations. Oral mucosa ulcer may be one of the oral manifestations of beta-thalassemia. The oral ulcer may resemble recurrent aphthous stomatitis (RAS). This current case report aims to present an aphthous oral ulcer as a manifestation in young adult women with beta-thalassemia. Case report: A 28-year-old woman complained of recurrent painful oral ulcers in the labial mucosa. She was diagnosed with beta-thalassemia intermedia three years before. The ulcer may take 3-4 weeks to heal completely. Intraoral examination revealed two yellowish ulc
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14

Zand, Nasrin, Leila Ataie-Fashtami, Parvin Mansouri, Mohsen Fateh, and Afshan Shirkavand. "Clinical Effect of Non-Thermal CO2 Laser Therapy (NTCLT) on Pain Relief of Oral Aphthous Ulcers of Behçet’s Disease." Journal of Lasers in Medical Sciences 12, no. 1 (2021): e72-e72. http://dx.doi.org/10.34172/jlms.2021.72.

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Introduction: Behçet’s disease (BD) is a debilitating and chronic vasculitis which can affect multiple organs. Recurrent oral aphthosis is the most common clinical feature of BD. The remarkable pain associated with painful oral ulcers can exert a major impact on the patients’ quality of life. Relieving pain of these oral ulcers is an essential approach in the management of mucocutaneous lesions of BD. Non-thermal CO2 laser therapy (NTCLT) as a novel photobiomodulative approach has recently been used for significant and immediate pain reduction of some types of painful oral lesions such as recu
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15

Mahmood, Abdulsattar S., Sahar G. Al-Kazzaz, and Maha T. Al-Saffar. "Histological assessment of the effect of ginger on the healing of chemically-induced aphthous ulceration in rabbits." Review of Clinical Pharmacology and Pharmacokinetics - International Edition 38, no. 3 (2024): 283–89. http://dx.doi.org/10.61873/derc5205.

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Background: An aphthous ulcer is a painful and recurrent oral mucosal inflammation that is retractable to treatments and resistant to healing. Conventional treatments include a variety of antiseptic, anti-inflammatory, and analgesic therapies, yet their efficacy remains inconsistent. Aim: The present study was conducted in order to evaluate the effects of ginger powder on the healing of chemically-induced aphthous ulcers in rabbits. Methodology: Twelve healthy rabbits were divided into control and ginger-treatment groups. Aphthous ulcers were induced in both groups. The treatment group receive
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16

Guintu, Ferdinand Z., and Antonio H. Chua. "Effectivity of Guava leaves (Psidium guajava) as Mouthwash for Patients with Aphthous Ulcers." Philippine Journal of Otolaryngology-Head and Neck Surgery 28, no. 2 (2013): 8–13. http://dx.doi.org/10.32412/pjohns.v28i2.469.

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Objective: To determine whether Psidium guajava leaves mouthwash is effective in the management of patients with aphthous ulcers
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 Study Design: Randomized prospective open label clinical study
 Setting: Tertiary Government Training Hospital
 Subjects: Thirty two patients diagnosed with aphthous ulcers were randomly divided into two groups, a treatment group using prepared guava leaves mouthwash, and a control group using isotonic sodium chloride solution mouthwash, given thrice a day for seven days. Patients were evaluated using a 10 point Visual Analog Scale. The
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17

Warrier, Aravind, Maguluru Sruthi, and K. Anbarasi. "Comprehensive management of major aphthous ulcer." BMJ Case Reports 14, no. 5 (2021): e241010. http://dx.doi.org/10.1136/bcr-2020-241010.

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Recurrent aphthous ulcers are the most prevalent oral mucosal disease, but the subset major aphthous ulcer is a less frequent type. These ulcers are refractory, may persist for several weeks to months, and interfere with the normal state of health. The aetiology is multifactorial and so is the treatment. We present a case of an adolescent male patient reported with multiple oral ulcers. He developed three ulcers simultaneously and suffered for 10 months despite using topical medications prescribed by different dental practitioners. We executed a multidisciplinary treatment approach that result
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18

Anushree, Tiwari. "Aphthous Ulcer: A Case Report." People's Journal of Scientific Research 16, no. 1 (2023): 1–3. https://doi.org/10.5281/zenodo.8077187.

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Mouth ulcers are quite common in all age groups. They can be linked to several conditions such as simple injury due to acute trauma or due to a sharp tooth or to an autoimmune disease. There are several medications available on the market to treat mouth ulcers. But do we need to prescribe a medication every time? This report presents a case of a 34-year-old male who presented with an ulcer in the palate and was treated without a prescription.
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Aleena, Sunny Ankitha George Anjali Jayakumar S.Hemalatha T.Sivakumar. "TOBACCO INDUCED APHTHOUS ULCERATION IN A 15 YEAR OLD BOY: A CASE REPORT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 9802–5. https://doi.org/10.5281/zenodo.1456649.

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Tobacco in all forms such as cigarettes, pipes, cigars, beedis, paan etc have been involved in development of ulcers that may lead to pre-malignancies or malignancies. Tobacco is a product prepared from the leaves of the tobacco plant of the genus Nicotiana and of the Solanaceae [nightshade] family. It is one of the most abused substances in the world. The addictive chemical present in tobacco is nicotine which is equally addictive as heroin, cocaine and alcohol. As per the epidemiological data provided by Centers for Diseases Control and Prevention tobacco causes 6 million deaths per year. To
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20

Prasad, Sudeep. "Understanding Aphthous Ulcers: Causes, Symptoms, and Management." Academia Journal of Medicine 6, no. 2 (2023): 7–12. http://dx.doi.org/10.62245/ajm.v6.i2.2.

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Aphthous ulcers, also known as canker sores, are a common and painful condition affecting the oral mucosa. This review article aims to provide an in-depth understanding of aphthous ulcers, including their causes, symptoms, and management. The article examines the different types of aphthous ulcers, their epidemiology, etiology, clinical presentation, and current treatment options.
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21

Nagihan, Bilal. "An Assessment of the Levels of Anxiety and Depression in Patients with Recurrent Aphthous Stomatitis." Archives of Otolaryngology and Rhinology 2, no. 1 (2016): 001–5. https://doi.org/10.17352/2455-1759.000011.

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<strong>Backgrounds:</strong> There is a lack of valid and reliable studies in literature on both the distinctive and ambiguous relationship between the psychological profile and the occurrence of recurrent aphthous ulcers in the individual.&nbsp; <strong>Objectives:</strong> The etiology of recurrent aphthous ulceration (RAU) is not well understood. This study analyzes the psychological treatment of patients with recurrent aphthous using valid, confidential and effective psychological measures.&nbsp; <strong>Materials:</strong> In this study we included 50 patients with recurrent aphthous sto
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Hagiya, Hideharu, Hiroyuki Hanakawa, Takayuki Katsuyama, and Fumio Otsuka. "Epiglottic Aphthous Ulcers." Internal Medicine 53, no. 15 (2014): 1731. http://dx.doi.org/10.2169/internalmedicine.53.2734.

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Aderaye, G. "Recurrent aphthous ulcers." Tobacco Control 4, no. 4 (1995): 399–400. http://dx.doi.org/10.1136/tc.4.4.399b.

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Hartsfield, Charles E. "APHTHOUS ULCERS REVISITED." Journal of the American Dental Association 132, no. 6 (2001): 724. http://dx.doi.org/10.14219/jada.archive.2001.0259.

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Taher, Aya K., and Nada Jafer MH Radhi. "Gingival health status in relation to salivary irisin in oral ulcerative patients of Diyala city, Iraq." Sumer 1 8, CSS 1 (2023): 1–6. http://dx.doi.org/10.21931/rb/css/s2023.08.01.11.

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Background: Gingivitis is the inflammation of the gingival tissue around the teeth initiated by bacteria. Irisin is a newly identified novel anti-inflammatory effect of adipocytokine. Recurrent aphthous ulcer (RAU) remains the most common ulcerative disease in the mucosa tissue of the oral cavity, existing as repeated onset of single or multiple painful ulcers. The study aims to evaluate gingival health status in relation to salivary irisin in oral ulcerative patients of Diyala City/ Iraq. The total sample consists of 200 patients taken from the specialized dental center in Ba'aquba / Diyala g
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Jin, Ying, Xiaoping Lin, Liming Song, et al. "The Effect of Pudilan Anti-Inflammatory Oral Liquid on the Treatment of Mild Recurrent Aphthous Ulcers." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/6250892.

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Recurrent aphthous ulcers are the most common recurrent oral mucosal lesions characterized by recurrence and pain. The aim of this research is to evaluate the short-term curative effect of the traditional Chinese medicine “Pudilan anti-inflammatory oral liquid” on mild recurrent aphthous ulcers. A total of 234 patients were divided into a treatment group and a control group. Both groups used vitamin B2 as the basis of treatment. The treatment group took a Pudilan anti-inflammatory oral solution for 8 days while the control group was given a liquid placebo. The ulcer size, pseudomembrane, perip
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Majid Al-Hamdani, Ghaith, and Layla Sabri Yas. "Serum and Salivary Ferritin Level in Relation to Iron Deficiency Patient with Recurrent Aphthous Stomatitis." Tikrit Journal for Dental Sciences 11, no. 2 (2024): 304–9. http://dx.doi.org/10.25130/tjds.11.2.16.

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Background: Rec urrent aphthous stomatitis (RAS) is one of the most widespread disorders affecting the oral mucosa, with a prevalence of 50–66%. This study investigated the serum and salivary levels of ferritin between participants with recurrent aphthous ulcers and healthy. Methods: A total of 75 individuals participated in the research separated into three groups, clinically healthy control group (n=25), iron deficiency anemi c patient with recurrent aphthous stomatitis (n=25), and iron deficiency anemic patient without recurrent aphthous stomatitis (n=25). The enzyme-linked immunosorbent as
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K. Mishra, Nikunja, Uma Mudi, Jyotirmayee Behera, and Amiyakanta Mishra. "INVESTIGATING THE EFFECTS OF POLYHERBAL GEL ON PHENOL-INDUCED ORAL APHTHOUS ULCERS IN RATS." INDIAN DRUGS 62, no. 02 (2025): 78–85. https://doi.org/10.53879/id.62.02.15037.

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Aphthous ulcers, commonly known as canker sores, are among the most widespread oral diseases globally. They typically occur on the non-keratinized mucosal surfaces inside the mouth, including the inner lips, floor of the mouth, and the underside of the tongue. Herbal therapy plays an important role in the healing process of diseases without causing any significant side effects. This study investigates the effects of polyherbal gel (PHG) on phenol-induced oral aphthous ulcers in rats. The rats were randomly assigned to five experimental groups; PHG 5%, 10% and 20% w/V were administered topicall
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Assiri, Hassan A., Ashwaq B. Majrashi, Reema K. Alqarni, and Mohammad S. Hameed. "Management of Concurrent Presentation of Aphthous Ulcer Major and Herpes Labialis." King Khalid University Journal of Health Sciences 10, no. 1 (2025): 88–91. https://doi.org/10.4103/kkujhs.kkujhs_31_24.

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Abstract Aphthous ulcers and herpes labialis (HL) are prevalent oral conditions, each with distinct origins and clinical appearances. Major aphthous ulcers, a variant of RAS, are less frequent and present as large recurrent, painful sores on the mucous membranes of the mouth, typically lacking a viral cause; their etiology appears to be multifactorial. In contrast, HL results from the reactivation of the herpes simplex virus, leading to clusters of vesicles primarily around the lip area. The co-occurrence of these conditions is unusual and can complicate both diagnosis and treatment due to the
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Slayter, Kathryn Lynn, and Thomas J. Marrie. "Treatment of Recurrent Aphthous Ulcers in an HIV Patient – An Emerging Use for Pentoxifylline." Canadian Journal of Infectious Diseases 9, no. 3 (1998): 189–90. http://dx.doi.org/10.1155/1998/569317.

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Patients with human immunodeficiency virus (HIV) infection often suffer from persistent, painful ulcers that commonly occur on the soft palate, buccal mucosa, tonsillar area or tongue, which are referred to as aphthous ulcers. This paper reports the case in which pentoxifylline was successfully used to treat recurrent aphthous ulcers in an HIV patient.
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Rutuja, Jaiswal* Tejaswini Dhawale Dr. Gajanan Sanap. "Herbs Therapies for Mouth Ulcer." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 2493–501. https://doi.org/10.5281/zenodo.14524961.

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Ulcer is a common disorder which is seen among many people. In most cases, it is an inflammatory skin rupture. There are many types of ulcers such as mouth ulcer, peptic ulcer, oesophagus ulcer, gastric ulcer. Among these mouth ulcers is common type of ulcer. Throughout the ages, treat a variety of illnesses and diseases. Mouth ulcers or aphthous ulcers are common oral lesions characterized by painful, shallow sores on the mucous membranes. This abstract explores the causes, symptoms, and potential treatments for mouth ulcers, emphasizing their impact on oral health and quality of life. Nowada
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32

Convissar, Robert A. "Aphthous ulcers and lasers." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 82, no. 2 (1996): 118. http://dx.doi.org/10.1016/s1079-2104(96)80211-3.

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McLeod, R. I. "Drug‐induced aphthous ulcers." British Journal of Dermatology 143, no. 6 (2000): 1138–39. http://dx.doi.org/10.1046/j.1365-2133.2000.04002.x.

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Zalaudek, Iris, Gianluca Petrillo, and Giuseppe Argenziano. "Aphthous ulcers and imiquimod." Journal of the American Academy of Dermatology 53, no. 2 (2005): 360–61. http://dx.doi.org/10.1016/j.jaad.2005.03.040.

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Borst, Johanna, and Lawrence Ma. "Oral ulcerations in a patient with autosomal dominant hyper-IgE syndrome (AD-HIES)." BMJ Case Reports 13, no. 11 (2020): e236705. http://dx.doi.org/10.1136/bcr-2020-236705.

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A 23-year-old woman with autosomal dominant hyper-IgE syndrome complicated by recurrent pneumonia and sinusitis presented with 1 week of multiple painful oral ulcers unresponsive to empiric antiviral and antifungal treatment. Her ulcers progressively worsened and she required hospitalisation for intravenous hydration and pain control. PCR swab of an ulcer was positive for varicella-zoster virus. Her symptoms never fully resolved despite antiviral therapy, and within 2 weeks, she relapsed with new and worsening ulcers. Biopsy revealed chronic active inflammation with no evidence of viral inclus
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Amrutha, V. Das, Kumar Jain Anchal, Goel Aditya, Prajapati Indraprakash, and Khan Rimsha. "Efficacy of Rebamipide Therapy in Aphthous Ulcers: A Prospective Study." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 817–20. https://doi.org/10.5281/zenodo.11100587.

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<strong>Background:&nbsp;</strong>Recurrent aphthous stomatitis (RAS) poses a considerable challenge within the Otorhinolaryngology domain, impacting patients&rsquo; quality of life.&nbsp;<strong>Aim and Objectives:</strong>&nbsp;This prospective study aimed to assess the efficacy of Rebamipide therapy in managing RAS over 3 months.&nbsp;<strong>Methods:&nbsp;</strong>A cohort of 60 patients with recurrent aphthous ulcers was enrolled, receiving Rebamipide therapy orally in a Tertiary care center of Central India. Clinical evaluations, pain scores, and ulcer healing rates were recorded at base
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CM Marya, Jiksha Mehlawat, Ruchi Nagpal, and Pratibha Taneja. "Low Level Laser Therapy (LLLT) in the Effective Management of Recurrent Aphthous Ulcers (RAU): Clinical Case Reporting 3 Patients: A Case Series." International Healthcare Research Journal 4, no. 12 (2021): CR4—CR8. http://dx.doi.org/10.26440/ihrj/0412.0399.

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Low-Level Laser therapy (LLLT) was employed for the treatment of three patients diagnosed with recurrent aphthous ulcers (RAU’s). The patients presented with recurrent aphthous ulcers in the region of floor of the mouth and buccal mucosa. The three patients with RAU’s were provided with a wavelength of946nm starting the use at 320µm fibre optic at a distance of 1-3 mm, peak power of 2W, frequency 10 Hz with no tissue contact in circular motion from outside to inside for 2 cycles with 100% duty for 30s for 3 consecutive days. The LLLT made possible an effective improvement in the reduction of p
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Dr. Arun Kumar M, Dr Arun Kumar M., Dr Vasanthi Ananthakrishnan, and Dr Jaisri Goturu. "Correlation of ulcer size and serum cortisol in subjects with Aphthous Ulcers." International Journal of Scientific Research 2, no. 11 (2012): 381–82. http://dx.doi.org/10.15373/22778179/nov2013/123.

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Hasan, Shamimul, and Ahmad Umar. "Major recurrent aphthous ulcers treated with 5% amlexanox oral paste and rebamipide tablets- A case report with a brief literature review." IP International Journal of Periodontology and Implantology 9, no. 3 (2024): 161–65. http://dx.doi.org/10.18231/j.ijpi.2024.033.

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Recurrent aphthous stomatitis (RAS) is the most prevalent ulcerative condition of the oral mucosa, frequently affecting otherwise healthy individuals. It appears as painful ulcers on the soft tissues of the mouth, especially on the buccal mucosa, labial mucosa, and tongue. RAS is categorized into minor, major, and herpetiform ulcers, depending on ulcer size, distribution, and the healing process. A detailed medical history and systemic evaluation can assist the physician in determining whether the condition is idiopathic or related to an underlying systemic ailment. disorder. The unclear etiol
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Taher, Aya K., and Nada JMH Radhi. "Salivary irisin in relation to recurrent aphthous ulcerand weight status in Diyala city/Iraq." Journal of Baghdad College of Dentistry 36, no. 1 (2024): 19–26. http://dx.doi.org/10.26477/jbcd.v36i1.3587.

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Background: Recurrent aphthous stomatitis remains the most common ulcerative disease of the oral mucosa that exists as painfull round shallow ulcers with a well-defined erythematous margin and a yellowish grey pseudomembranous centre. Salivary irisin is an identified adipomyokine and research has revealed that it has an anti-inflammatory effect and is a novel myokine; it is synthesized in skeletal muscle and adipose tissue. The aim of the present study was to evaluate the relation of salivary irisin to recurrent aphthous ulcers and weight status in Diyala City / Iraq. Materials and methods: A
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Ranit, Pranoti, Mrunal Meshram, Renu Rathi, Devyani Taori, Priyanka Paul Madhu, and Amit Reche. "A Randomised Control Trial comparing the efficacy of Jati Ghrita and 1% Chlorhexidine Gluconate on Aphthous Stomatitis." International Journal of Ayurvedic Medicine 14, no. 2 (2023): 423–29. http://dx.doi.org/10.47552/ijam.v14i2.3346.

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Background: Aphthous ulcer is seen to be one of the most commonly occurring ailments found among patients that dentists may come across on a daily basis. Taking into consideration the agents that have been used for treatment of aphthous stomatitis, it would seem advisable to apply the agent that is the safest and has the least toxic properties that can bring about symptomatic relief and that can be applied topically. These days, there are few reliable natural remedies that are emerging as a therapy for aphthae. Herbal and polyherbal medicines will alleviate pain, induce healing, prevent infect
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CM, Marya, Mehlawat Jiksha, Nagpal Ruchi, and Taneja Pratibha. "Low Level Laser Therapy (LLLT) in the Effective Management of Recurrent Aphthous Ulcers (RAU): Clinical Case Reporting 3 Patients: A Case Series." International Healthcare Research Journal 4, no. 12 (2021): CR4—CR8. https://doi.org/10.26440/IHRJ/0412.0399.

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Low-Level Laser therapy (LLLT) was employed for the&nbsp; treatment of three patients diagnosed with recurrent aphthous ulcers (RAU&rsquo;s). The patients presented with recurrent aphthous ulcers in the region of floor of the mouth and buccal mucosa. The three patients with RAU&rsquo;s were provided with a wavelength of946nm starting the use at 320&micro;m&nbsp; fibre optic at a distance of 1-3 mm, peak power of 2W, frequency 10 Hz with no tissue contact in circular motion from outside to inside for 2 cycles with 100% duty for 30s for 3 consecutive days. The LLLT made possible an effective imp
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Wang, Dan. "New Progress in the Integrated Treatment of Traditional Chinese and Western Medicine for Recurrent Aphthous Ulcer in the Oral Cavity." International Journal of Public Health and Medical Research 1, no. 3 (2024): 85–87. http://dx.doi.org/10.62051/ijphmr.v1n3.12.

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Recurrent aphthous ulcer in the oral cavity is a common oral mucosal disease with periodic, recurrent, and self-limiting characteristics. This article aims to explore the new progress of integrated traditional Chinese and Western medicine in the treatment of recurrent aphthous ulcers in the oral cavity. Through a comprehensive analysis of relevant research, the advantages and mechanisms of integrated traditional Chinese and Western medicine in improving efficacy, reducing symptoms, and reducing recurrence rates are elaborated, providing reference for clinical treatment.
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Kolenko, Y., A. Sinko, and N. Gryg. "Systemic immune inflammation index as a useful prognostic indicator in the prediction of chronic aphthous stomatitis." SUCHASNA STOMATOLOHIYA 121, no. 4 (2024): 12. http://dx.doi.org/10.33295/1992-576x-2024-4-12.

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Relevance. Chronic recurrent aphthous stomatitis (RAS) is one of the most common chronic inflammatory diseases of the oral cavity, which affects approximately 5 to 25% of the population. RAS is a multifactorial disorder, and studies have pointed to several potential causes associated with its occurrence. The aim is to analyse the role of inflammatory markers in the development of chronic recurrent aphthous stomatitis. Materials and methods. The study involved 80 patients: 29 men (36.25%) and 51 women (63.75%) with RAS who sought help at the Department of Therapeutic Dentistry of the Bogomolets
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Darakhshan, Sara, Mohammad Malmir, Fereshteh Bagheri, et al. "The effects of pomegranate peel extract on recurrent aphthous stomatitis." Current Issues in Pharmacy and Medical Sciences 32, no. 3 (2019): 115–20. http://dx.doi.org/10.2478/cipms-2019-0021.

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Abstract As high as 20% of the population is thought to have recurrent aphthous stomatitis (RAS), hence, finding new therapeutic agents may be needed. Pomegranate (Punica granatum), has been extensively used in the folk medicine of many cultures, as it possesses antioxidant, anti-inflammatory and anti-bacterial properties. In this study, it is hypothesized that a topical form of pomegranate peel extract (PPE) may shorten the duration, accelerate the healing and reduce the pain of RAS patients. The presented randomized, double-blind study was conducted on 56 patients. Herein, 28 patients were a
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Khozeimeh, Faezeh, Zahra Saberi, Atefeh Tavangar, and Fahime Fakhari Badi. "Effect of Herbal Echinacea on Recurrent Minor Oral Aphthous Ulcer." Open Dentistry Journal 12, no. 1 (2018): 567–71. http://dx.doi.org/10.2174/1874210601812010567.

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Background: The oral aphthous is a common oral ulcer with intense pain and there is no treatment for it, yet. Echinacea is an herbal medicine that moderated the immune system. Objective: The aim of this study was to investigate the effects of Echinacea on the treatment of aphthous ulcer. Methods: 50 patients with minor aphthous participated in our study. 25 patients take 3 tablets in a day for five weeks (case group) and 25 patients didn’t take any tablets (control group). The patients were monitored for one month before taking the tablets for six months. During this period, the number of lesi
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Rana, Surinder Singh, Vishal Sharma, Ravi Sharma, Ritambhra Nada, Rajesh Gupta, and Deepak Kumar Bhasin. "Capsule endoscopy in small bowel Crohn’s disease and Tuberculosis." Tropical Doctor 47, no. 2 (2017): 113–18. http://dx.doi.org/10.1177/0049475516686542.

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Differentiation of small bowel tuberculosis (SBTB) from Crohn’s disease (CD) is a diagnostic challenge. We studied 52 patients with suspected SBTB or CD with terminal ileal involvement, who were prospectively enrolled. After confirming patency of the gastrointestinal tract, 26 patients underwent capsule endoscopy (CE). A final diagnosis of CD was found in 18 patients and SBTB in eight patients. All SBTB patients had involvment of the ileocecal valve (ICV) with large (n = 6) and aphthous (n = 2) ulcers in the ileal segment. In CD, ICV involvement was seen in five (33%) patients. Large and aphth
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Hernawati, Sri. "Management of Recurrent Aphthous Stomatitis in a Patient with High Recurrence Frequency." Health Notions 4, no. 4 (2020): 102–8. http://dx.doi.org/10.33846/hn40401.

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RAS (Recurrent Aphthous Stomatitis) is an inflammation of soft tissues of the oral cavity characterized by recurrent and painful ulcers. These lesions can be marked early on with a burning sensation, and when the wound has formed, the pain is getting worse. Occasional symptoms of precursors, paresthesia and hyperesthesia, are sometimes reported. Pain and discomfort arise along movement around the ulcer e.g. eating, talking and swallowing. Characteristics of RAS are usually single or multiple ulcers occurring recursively on the oral mucosa, round or oval in shape, clearly demarcated, with a gra
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Jesudoss Prabhakaran, AC, and JP Angeline Archana. "Pharmacotherapy of recurrent aphthous ulcers." Chronicles of Young Scientists 2, no. 3 (2011): 134. http://dx.doi.org/10.4103/2229-5186.90889.

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Bittoun, Renée. "Recurrent aphthous ulcers and nicotine." Medical Journal of Australia 154, no. 7 (1991): 471–72. http://dx.doi.org/10.5694/j.1326-5377.1991.tb121180.x.

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