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Rozprawy doktorskie na temat „Arrhythmia”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Walfridsson, Ulla. "Assessing Symptom Burden and Health-Related Quality of Life in patients living with arrhythmia and ASTA : Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia." Doctoral thesis, Linköpings universitet, Omvårdnad, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71873.

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Background: Health-Related Quality of Life (HRQOL) can be negatively affected in patients living with arrhythmias and many patients experience a pronounced symptom burden. The arrhythmia can cause both uncertainty and limitations, including interference with work, reluctance to perform and plan for leisure activities and leading to self-imposed restrictions in daily life situations. There are patients striving to find strategies to manage the arrhythmia and for some this can become the focus in their lives. Treatment options are often a choice between pharmaceuticals and radiofrequency ablatio

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2

Williams, Steven Edwin. "Characterisation and representation of arrhythmia substrates." Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/characterisation-and-representation-of-arrhythmia-substrates(b591acfd-9ca4-45a0-a3b0-169128bac9d7).html.

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Cardiac arrhythmias arise from a variety of structural and electrical substrates and range in clinical presentation from asymptomatic to severely disabling or life threatening. Existing techniques for the characterisation of arrhythmia substrates include surface electrocardiography and intracardiac mapping together with ultrasound, computed tomography and magnetic resonance imaging. In this thesis I study a spectrum of arrhythmia characterisation techniques to improve the understanding of complex arrhythmia mechanisms. The role of surface electrocardiography and intra-cardiac contact mapping t

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3

Fischer, Lindsey Ann. "How Emotions Affect Respiratory Sinus Arrhythmia." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/579276.

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Respiratory sinus arrhythmia (RSA) is a measure of heart rate variability in relation to respiration. The current study investigated how the different induced emotional states (i.e., amusement, anger, disgust, happiness, fear, and sadness) affect RSA. This was done by comparing resting RSA to that occurring while watching short film clips intended to induce emotional states. It was hypothesized that RSA would be lower when negative emotions are induced and higher when positive emotions are induced. A difference between the resting RSA and RSA measured during emotion induction was also anticipa

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4

Ware, James. "Genomic dissection of arrhythmia and cardiac electromechanics." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/39405.

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Cardiac arrhythmia is a leading cause of death in the developed world and a final common pathway for many forms of cardiac disease. Rare inherited arrhythmia syndromes contribute to this disease burden, particularly through sudden death in the young. The study of rare syndromes, such as inherited arrhythmia, can also identify genes and pathways important in common diseases. Here, genomic approaches were applied to dissect genetic determinants of cardiac arrhythmia, through gene discovery, variant discovery, and variant annotation. First, whole-exome sequencing was used to identify the genetic

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5

Kehrle, Florian [Verfasser]. "Inverse simulation for cardiac arrhythmia / Florian Kehrle." Magdeburg : Universitätsbibliothek, 2018. http://d-nb.info/1160593698/34.

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6

Soto-Freita, Angelica Marie. "Parent Predictors of Infant Respiratory Sinus Arrhythmia." TopSCHOLAR®, 2016. http://digitalcommons.wku.edu/theses/1628.

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The development of emotion regulation skills is an imperative task early in development. Respiratory sinus arrhythmia (RSA), a physiological proxy of regulation, is indicative of one’s regulatory capacity and can be predictive of behavior in later life (Graham, Ablow, & Measelle, 2010; Moore, 2010). Children begin regulating their emotions at a physiological level early in infancy. Infants who are able to properly suppress RSA have higher quality social interactions in childhood (Graziano, Keane, & Calkins, 2007). Previous work has suggested that parents play a role in predicting infant RSA (C

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7

Labarge, Isaac E. "Neural Network Pruning for ECG Arrhythmia Classification." DigitalCommons@CalPoly, 2020. https://digitalcommons.calpoly.edu/theses/2136.

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Convolutional Neural Networks (CNNs) are a widely accepted means of solving complex classification and detection problems in imaging and speech. However, problem complexity often leads to considerable increases in computation and parameter storage costs. Many successful attempts have been made in effectively reducing these overheads by pruning and compressing large CNNs with only a slight decline in model accuracy. In this study, two pruning methods are implemented and compared on the CIFAR-10 database and an ECG arrhythmia classification task. Each pruning method employs a pruning phase inter

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8

Goetz, Paul W. "Worry, Respiratory Sinus Arrhythmia, and Health Behaviors." Bowling Green State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1308552215.

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9

Korhonen, Petri. "Magnetocardiography in assessment of ventricular arrhythmia risk." Helsinki : University of Helsinki, 2002. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/korhonen/.

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10

Ye, Yanping. "Designing New Drugs to Treat Cardiac Arrhythmia." PDXScholar, 2012. https://pdxscholar.library.pdx.edu/open_access_etds/638.

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Heart failure resulting from different forms of cardiomyopathy is defined as the inability of the heart to pump sufficient blood to meet the body's metabolic demands. It is a major disease burden worldwide and the statistics show that 50% of the people who have the heart failure will eventually die from sudden cardiac death (SCD) associated with an arrhythmia. The central cause of disability and SCD is because of ventricular arrhythmias. Genetic mutations and acquired modifications to RyR2, the calcium release channel from sarcoplasmic reticulum, can increase the pathologic SR Ca2+ leak during

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11

Glandberger, Oliver, and Daniel Fredriksson. "Neural Network Regularization for Generalized Heart Arrhythmia Classification." Thesis, Blekinge Tekniska Högskola, Institutionen för datavetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-19731.

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Background: Arrhythmias are a collection of heart conditions that affect almost half of the world’s population and accounted for roughly 32.1% of all deaths in 2015. More importantly, early detection of arrhythmia through electrocardiogram analysis can prevent up to 90% of deaths. Neural networks are a modern and increasingly popular tool of choice for classifying arrhythmias hidden within ECG-data. In the pursuit of achieving increased classification accuracy, some of these neural networks can become quite complex which can result in overfitting. To combat this phenomena, a technique called r

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12

Long, Victor P. III. "Modulation of the Arrhythmia Substrate in Cardiovascular Disease." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1459777728.

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13

Chai, Shin Luen Chai. "Novel Genetic Modifiers in a Monogenic Cardiac Arrhythmia." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1516618028568975.

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14

Gray, Belinda Ruth. "Clinical and Genetic Studies in Inherited Arrhythmia Syndromes." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15994.

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Inherited arrhythmia syndromes, or “ion channelopathies”, is a term encompassing a number of different diseases including long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), Brugada syndrome (BrS), short QT syndrome (SQTS) and idiopathic ventricular fibrillation (IVF). In inherited arrhythmia syndromes, ventricular arrhythmias originate due to abnormalities with intracellular ion channels, predominantly involving potassium, sodium and calcium handling, due to genetic mutations in genes encoding for channel proteins. The cellular abnormalities in these conditi

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15

Lee, Ying-siu Andrew, and 李應紹. "Endogenous opioid peptides and cardiac arrhythmias." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1988. http://hub.hku.hk/bib/B31231275.

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16

Lee, Ying-siu Andrew. "Endogenous opioid peptides and cardiac arrhythmias /." [Hong Kong] : University of Hong Kong, 1988. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12358812.

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17

Kalla, Manish. "Mechanistic insights in the automatic modulation of ventricular arrhythmia." Thesis, University of Oxford, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.714086.

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18

Kalla, Manish. "Mechanistic insights in the autonomic modulation of ventricular arrhythmia." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:019a87c7-322d-4d0b-befa-0da43378b13f.

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Cardiovascular disease is the leading cause of mortality in the developed world with up to fifty percent of cases being due to sudden cardiac death. Changes in sympatho-vagal balance underpin many cardiovascular conditions including heart failure and myocardial infarction. Neuraxial modulation of the autonomic nervous system is an emerging therapy to prevent ventricular arrhythmias, the main cause of sudden cardiac death. <b>Chapter One</b> reviews our current understanding of how the cardiac autonomic nervous system influences ventricular arrhythmogenesis. A particular focus was on the contro

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19

Hibbert, Anita S. "Depression and anxiety : differing relationships to respiratory sinus arrhythmia." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43112.

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Many theoretical models addressing the role of the parasympathetic branch of the autonomic nervous system in psychopathology predict decreased respiratory sinus arrhythmia (RSA) in disorders such as depression and anxiety. However, decreased RSA in depression is not consistently observed across studies. Research on the relationship between anxiety and RSA has also been mixed, but the results may be more robust than that of depression. Before the theoretical models can be re-examined based on these findings, researchers must clarify the nature of these relationships. Specifically, three things

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20

Deshmane, Anagha Vishwas. "False arrhythmia alarm suppression using ECG, ABP, and photoplethysmogram." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54209.

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Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2009.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (p. 91-93).<br>A signal quality assessment scheme for the photoplethysmogram waveform recorded by a pulse oximeter has been created. The signal quality algorithm uses statistical methods on time-series and spectral analysis to locate h

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21

Ives, Rachel Ayn. "Respiratory Sinus Arrhythmia as a Function of Cognitive Attention." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/297655.

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RSA was assessed from electrocardiographic recordings from 95 individuals between the ages of 18 and 22 at resting, and while they were completing three tasks. The tasks were computerized performance tasks that provided increasing levels of difficulty and memory load. Subjects were asked to respond when the same letter repeated itself either one back, two back, or three back, depending on the task. The number of true positives declined as the tasks became increasingly difficult, and the number of false positives increased between the one back task and the two back task, but decreased between t

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22

Zhu, Chenhong. "New insight into models of cardiac caveolae and arrhythmia." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/1945.

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Recent studies suggest that cardiomyocyte membrane microdomains, caveolae and transverse tubules, play a key role in cardiac arrhythmia. Mutation of caveolin-encoding genes CAV3, co-expressed with genes of caveolae ion channels, leads to a late persistent sodium currents and delayed repolarization stage, called LQT9 disease. A simplified three-current model is created to largely reduce the well-known Pandit rat ventricular myocyte model. The mathematical tractability of the three-current model allows us to conduct asymptotic analysis and efficiently estimate action potential duration. Improvem

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23

Zhou, Yuan. "Ionic mechanisms of chloroform-induced cardiac arrhythmias." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43085325.

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24

Tie, Hii Hui Clinical School St Vincents UNSW. "Cellular mechanisms of QT prolongation and proarrhythmia induced by non-antiarrhythmic drugs." Awarded by:University of New South Wales. Clinical School - St. Vincents, 2002. http://handle.unsw.edu.au/1959.4/19035.

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A variety of drugs prolong cardiac repolarization (manifested as QT prolongation on ECG), although the major example are the so-called class III antiarrhythmics. However, antiarrhythmic drugs which prolong cardiac repolarization are not harmless, as they may also be proarrhythmic, inducing a potentially fatal arrhythmia known as torsade de pointes (TdP). Recently, it has become apparent that a wide variety of non-antiarrhythmic agents may also, as an entirely undesired side-effect, provoke TdP. TdP is also characteristic of the congenital long QT syndrome, one form of which is caused by mutati

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25

Lesiuk, Veronika. "Respiratory sinus arrhythmia : interaction of breathing frequency and heart rate changes." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81356.

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Heart rate variability is commonly interpreted as a measure of vagal tone. Changes in heart rate variability and more specifically respiratory sinus arrhythmia (RSA) are however also commonly observed when breathing is altered without changes in heart. This study examined how decreasing vagal tone through a low level (6%MVC) handgrip (HG) contraction and changing breathing frequency, alone or in combination, affected heart rate variability and respiratory sinus arrhythmia. ECG and respiratory recordings were obtained in 16 university students. Results show that decreasing breathing rate

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26

Xu, Weichao. "Real time detection of supraventricular arrhythmias /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?

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27

徐維超 and Weichao Xu. "Real time detection of supraventricular arrhythmias." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31243848.

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28

Abrams, Dominic James Richard. "Mechanisms and mapping of arrhythmia rate after the Fontan procedure." Thesis, Queen Mary, University of London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497623.

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29

Finlay, M. "Interactions between activation and repolarisation in predisposition towards cardiac arrhythmia." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1429926/.

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The lethal cardiac arrhythmias ventricular fibrillation (VF) and ventricular tachycardia (VT) are a leading cause of death in heart disease. We hypothesised that dynamic activation and repolarisation interactions will vary according to autonomic tone and the nature of the myocardial substrate as affected by disease states. This hypothesis was tested in a series of human and murine experiments. Incorporation of data from human electrophysiological studies into a linear computer model was able to predict activation dynamics of sequential extrastimuli. This served as a validation of the concept o

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30

Patel, Nehal Jaymish. "Novel Pathways for the Regulation of Cardiac Fibrosis and Arrhythmia." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586891209137927.

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31

Schredelseker, Johann [Verfasser]. "Targeting cardiac arrhythmia by enhancing mitochondrial calcium uptake / Johann Schredelseker." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1221960741/34.

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32

Wolf, Roseanne Marie. "Defining new insight into fatal human arrhythmia: a mathematical analysis." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/3013.

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Background: Normal cardiac excitability depends upon the coordinated activity of ion channels and transporters. Mutations in genes encoding ion channels affecting their biophysical properties have been known for over twenty years as a root cause of potentially fatal human electrical rhythm disturbance (arrhythmias). More recently, defects in ion channel associated protein (e.g. adapter, regulatory, cytoskeletal proteins) have been shown to cause arrhythmia. Mathematical modeling is ideally suited to integrate large volumes

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33

Metcalf, Robert Glenn. "Strategies for increasing consumption of N-3 polyunsaturated fatty acids and their effects on cardiac arrhythmias in humans." Title page, table of contents and abstract only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09phm5885.pdf.

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"October 2003" Bibliography: leaves 190-210. Ch. 1. Literature review -- Ch. 2. A practical approach to increasing intakes of n-3 polyunsaturated fatty acids: use of novel foods enriched with n-3 fats -- Ch. 3. Effects of fatty acids on the incidence of arrhythmias in patients with implanted cardioverter-defibrillators (ICDs) -- Ch. 4. A pilot study to investigate the effects of n-3 fatty acids on inducible, sustained ventricular tachycardia in patients undergoing electrophysiology testing -- Ch. 5. Conclusions and future directions.

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34

Betts, Timothy Rider. "Atrial architecture and electrical activation." Thesis, University of Southampton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288446.

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35

Martin, Claire Adriana. "Mechanisms of arrhythmogenesis in a murine model of Brugada syndrome." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648347.

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36

Liu, Pak-yin Anthony, and 廖柏賢. "Genetic counseling in sudden arrhythmia death syndrome : the science and the art." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196059.

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Background: Sudden arrhythmia death syndrome (SADS) is a genotypically and phenotypically heterogeneous condition that might produce fatal ventricular arrhythmia in otherwise healthy individuals. Congenital long QT syndrome (LQTS) is the most common type of SADS with a frequency of 1 in 2500 individuals. Up to 13 genes have been shown to be associated with LQTS and genetic testing has a role in disease diagnosis, prognostication, treatment guidance, cascade testing, and reproductive counseling. Interdisciplinary care is the standard but such service is unavailable in Hong Kong. Objectives:

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37

Matthews, Gareth David Kingsley. "The rate-dependence of pro-arrhythmic properties in murine SCN5A+/- hearts modeling the Brugada syndrome." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648741.

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38

Reddy, Mairi Helen. "Beta adrenergic function in acute myocardial ischaemia." Thesis, University of Edinburgh, 1989. http://hdl.handle.net/1842/19257.

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39

Scott, Adrienne S. "Comparison of respiratory sinus arrhythmia integration in athletes and non-athletes." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33924.

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A comparison of heart rate viability and respiratory sinus arrhythmia (RSA) characteristics was performed in 20 athletes and 12 age-matched sedentary controls (CTRL) (22 +/- 2.4 yrs). More specifically, this study examined the role of regular physical activity on the breathing frequency (BF)---RSA amplitude response curve comparing varsity swimmers (SW) to endurance runners (RU) to test the hypothesis that a locomotor-respiratory entrainment resulting from the water-immersion breathing pattern of swimmers would alter their respiratory related cardiac vagal integrative response. Spectral power

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40

Petchdee, Soontaree. "Arrhythmia mechanisms in acute ischaemia and chronic infarction in rabbit heart." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1327/.

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In this thesis, a method for studying the electrophysiological consequences of acute regional ischaemia in rabbit heart was established using a combination of a novel snare technique and optical mapping. The purpose of this approach was to discover the mechanistic link between acute coronary infarction and the occurrence of arrhythmias. The electrophysiology of the epicardial surface of isolated hearts was examined using the voltage sensitive dye RH237 and optical action potentials were recorded from a 13x13mm area of left ventricular epicardium using a 16x16 element Hamamatsu photodiode array

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41

Condy, Emma Elizabeth. "Respiratory Sinus Arrhythmia and Restricted Repetitive Behaviors in Autism Spectrum Disorder." Thesis, Virginia Tech, 2016. http://hdl.handle.net/10919/78124.

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In addition to social communication deficits, restricted repetitive behaviors (RRBs) are a key diagnostic feature of autism spectrum disorder (ASD). Two theories regarding the etiology of RRBs in ASD have been proposed: the hyper-arousal theory, and the hypo-arousal theory. Both of these theories posit the autonomic nervous system (ANS) as being dysfunctional in ASD, resulting in the occurrence of RRBs. Many studies investigating ANS activity in ASD have focused solely on its relation to social functioning. The few that have addressed RRBs have had inconclusive findings. Not only do the curren

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42

Bernhardt, Madison Nicole. "Reinterpretation of Genetic Variants from a Cohort of Pediatric Arrhythmia Patients." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523624250940948.

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Sheikh, Abdul Kadir Siti Hamimah. "Molecular mechanisms for fetal cardiac arrhythmia in intrahepatic cholestasis of pregnancy." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6164.

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Intrahepatic cholestasis in pregnancy (ICP) is characterized by raised serum bile acids which can cause fetal complications, including preterm labour and intrauterine death. The fetal death in ICP is not well understood. In this thesis, the mechanisms of bile-acid induced arrhythmia were studied extensively using in vitro models of the fetal heart. Addition of the bile acid taurocholate (TC) to cardiomyocytes led to a reduction in the rate and amplitude of contraction, dysregulation of beating and desynchronization of intracellular calcium release. The results obtained from both differentiated

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44

Raphisak, Pisut. "Study of the Kalman filter for arrhythmia detection with intracardiac electrograms." Morgantown, W. Va. : [West Virginia University Libraries], 1999. http://etd.wvu.edu/templates/showETD.cfm?recnum=1098.

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Thesis (M.S.)--West Virginia University, 1999.<br>Title from document title page. Document formatted into pages; contains viii, 143 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. [80]-85).

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45

Martins, Jose L. M. G. "A Rapid Access Arrhythmia Clinic for the Diagnosis and Management of Incident Atrial Fibrillation and Other Cardiac Arrhythmias : The Imperial College New Atrial Fibrillation Study." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520897.

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46

Zhou, Yuan, and 周嫄. "Ionic mechanisms of chloroform-induced cardiac arrhythmias." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085325.

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47

Hörnsten, Rolf. "Cardiac arrhythmias and heart rate variability in familial amyloidotic polyneuropathy : a clinical study before and after liver transplantation /." Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1407.

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48

Lopes, Philippe. "The relationships between respiratory sinus arrhythmia and coronary heart disease risk factors." Thesis, University of Ulster, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287137.

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49

Fiore, Paul Vincent. "Interaction of cocaine and sprint-training on ventricular arrhythmia in the rat /." The Ohio State University, 1988. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487588939087915.

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50

Montazeri, Ghahjaverestan Nasim. "Early detection of cardiac arrhythmia based on Bayesian methods from ECG data." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1S061/document.

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L'apnée est une complication fréquente chez les nouveaux-nés prématurés. L'un des problèmes les plus fréquents est l'épisode d'apnée bradycardie dont la répétition influence de manière négative le développement de l'enfant. C'est pourquoi les enfants prématurés sont surveillés en continu par un système de monitoring. Depuis la mise en place de ce système, l'espérance de vie et le pronostic de vie des prématurés ont été considérablement améliorés et ainsi la mortalité réduite. En effet, les avancées technologiques en électronique, informatique et télécommunications ont conduit à l'élaboration d

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