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Rozprawy doktorskie na temat „Arterial stenoses”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Tait, W. F. "The use of continuous wave ultrasound to diagnose stenoses in the carotid arteries." Thesis, University of Glasgow, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381464.

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2

Biz, Sophie. "Flow in collapsible stenoses : an experimental study." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/18244.

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3

Etebari, Ali. "Wall shear measurements in arterial flows." Diss., Virginia Tech, 2006. http://hdl.handle.net/10919/27326.

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Cardiovascular disease is responsible for the majority of morbidity and mortality in the United States. Physiologically healthy flow rarely displays turbulent behavior, thereby maintaining normal shear levels. The presence of vortical flow structures, however, alters the hemodynamical characteristics within the system, which has significant effect upon shear stress (SS) and wall shear stress (WSS) levels, as well as particle residence times. The relationship between these hemodynamic parameters and vascular injury response is of great relevance to understanding the cardiovascular disease proc

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4

Konala, Bhaskar Chandra. "Effect of Arterial Wall-Stenosis Compliance on Coronary Diagnostic Parameters." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1291146768.

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5

Flannery, Conor James. "Thrombus Formation under High Shear in Arterial Stenotic Flow." Thesis, Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/6943.

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Acute thrombotic and thromboembolic occlusion of atherosclerotic vessels are events that precipitate most heart attacks and strokes. In arterial stenotic flow, thrombus formation is shear dependent and may or may not lead to complete occlusion of the vessel. Platelets in whole blood adhere to collagen-coated surfaces and as they accumulate the resistance of the stenosis increases because of the decreasing passageway of the occluded stenosis. As a model of blood clotting in stenoses, porcine blood is heparinized and perfused over tubular glass test sections that are coated with collagen type

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6

Simons, Dianne Margaret. "The hydrodynamics of idiopathic hypertrophic subaortic stenosis." Thesis, Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/10257.

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7

Siegel, John Mather Jr. "Wall shear stress through an arterial stenosis and its implications to thrombosis." Thesis, Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/17674.

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8

Molla, Md Mamun. "LES of pulsatile flow in the models of arterial stenosis and aneurysm." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/905/.

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The Large Eddy Simulation (LES) technique is used to simulate the different types of Newtonian and non-Newtonian pulsatile blood flow in a constricted as well as in a dilated channel to gain insight of the transition-to-turbulent blood flow due to the arterial stenosis and aneurysm. In the stenosed model, a cosine shape stenosis is placed at the upper wall of a 3D channel which reduces the cross-sectional area, whereas the aneurysm which is also placed at the upper wall dilates the channel cross-sectional area. In LES, a top-hat spatial grid-filter is applied to the Navier-Stokes equations of

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9

Hye, Md Abdul. "Simulation of transient blood flow in models of arterial stenosis and aneurysm." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3836/.

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The Large Eddy Simulation (LES) technique with the Smagorinsky-Lilly dynamic subgrid model and two-equation Standard k-ω Transitional turbulence model are applied to investigate non-spiral and spiral blood flow through three dimensional models of arterial stenosis and aneurysm. A spiral pattern of blood flow is thought to have many beneficial effects on hemodynamics. Previous computational studies on spiral blood flow involve only steady spiral flow in a straight stenosed pipe without considering an upstream curved section of the artery. But a spiral pattern in the blood flow may exist due to

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10

Lara-Montalvo, Ruben Angel. "Ultrasound determination of absolute backscatter from arterial wall structures." Link to electronic thesis, 2002. http://www.wpi.edu/Pubs/ETD/Available/etd-1203102-165958.

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11

Ghalichi, Farzan. "Pulsatile laminar and turbulent blood flow simulation in large stenosed arteries and stenosed carotid artery bifurcation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0013/NQ36272.pdf.

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12

Chan, Weng Yew, and chanwengyew@gmail com. "Simulation of arterial stenosis incorporating fluid-structural interaction and non-Newtonian blood flow." RMIT University. Aerospace, Mechanical and Manufacturing Engineering, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20070108.164458.

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The aim of this study is to investigate the fluid-structural response to pulsatile Newtonian and non-Newtonian blood flow through an axisymmetric stenosed vessel using FLOTRAN and ANSYS. This is to provide a basic understanding of atherosclerosis. The flow was set to be laminar and follows a sinusoidal waveform. The solid model was set to have isotropic elastic properties. The Fluid-Structural Interaction (FSI) coupling was two-way and iterative. Rigid and Newtonian cases were investigated to provide an understanding on the effects of incorporating FSI into the model. The wall ex

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13

Kuchlbauer, Stephanie. "Transplantatnierenarterienstenose : perkutane transluminale Angioplastie als First-Line-Therapie." kostenfrei, 2008. http://www.opus-bayern.de/uni-regensburg/volltexte/2009/1116/.

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14

Powell, Barry Edward. "Experimental measurements of flow through stenotic collapsible tubes." Thesis, Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/18377.

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15

Balu, Niranjan. "Quantitative characterization of carotid arterial remodeling by high-resolution serial MRI /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8112.

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16

Dave, Parth Pranavbhai. "Numerical simulation of blood flow in arterial stenosis under steady and pulsatile flow conditions." Thesis, Wichita State University, 2011. http://hdl.handle.net/10057/3949.

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Cardiovascular diseases (CVDs) are among the leading causes of death in the world. In this study, an attempt was made to model the flow dynamics of blood in abnormally narrowed artery. Finite volume solver FLUENT was used for the analysis with the aim of understanding the consequences of increasing the degree of stenosis using a two-equation turbulence model. The compliant nature of the artery was neglected, and Newtonian behavior of the blood flow was assumed for the larger arteries. Steady-flow simulations with 75% area reductions were used to establish the validity of the current models by

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17

Shrum, Jeff. "Platelet adhesion in an asymmetric stenosis flow model." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100235.

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Platelets have been shown to be a main contributor to thrombus formation in stenotic arteries leading to acute coronary syndromes. It is thought that increased activation and adhesion of platelets under variable shear and complex flow conditions contribute to thrombosis. The objective of this work was to evaluate the relationship between asymmetric stenosis hemodynamics and platelet adhesion using in-vitro models developed to properly simulate physiological conditions. In this study, platelet rich plasma was circulated through stenotic and straight coronary artery models. Adhesion results were

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18

Haeck, Luc Bernard Arthur. "C W Doppler audiospectrum analysis in the iliac arteries." [Maastricht : Maastricht : Rijksuniversiteit Limburg] ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5512.

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19

Beeck, Nicolai. "Prädiktoren für das Schicksal von Patienten mit hochgradiger Arteria carotis interna-Stenose /." München, 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000276785.

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20

Pincombe, Brandon. "A study of non-Newtonian behaviour of blood flow through stenosed arteries /." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09php6469.pdf.

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21

Zeigler, Marvin N. "One dimensional inviscid flow through a stenotic collapsible tube." Thesis, Georgia Institute of Technology, 1989. http://hdl.handle.net/1853/17515.

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22

Engineer, Hoshang K. "Mathematical modeling of platelet deposition in arterial stenosis with major emphasis on fluid flow effects." FIU Digital Commons, 1999. http://digitalcommons.fiu.edu/etd/3144.

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The intention of this study is to develop a numerical model that depicts flow and platelet behavior in a coronary stenosis, which contribute towards thrombosis, leading to possible embolism and sudden death. The model is intended to be the first step in applying a realistic approach to predict platelet behavior due to existing flow conditions. Using a 2-D axisymmetric geometry a two-phase turbulent flow is solved using statistically assigned variable boundary conditions at the wall. Platelets are released into the flow (Re = 300) and their convective transport is governed through turbulent mod

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23

Lee, Ka Wai. "Numerical analysis of blood flow and wall mechanics in stenosed arteries." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398341.

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24

Ang, Keng Cheng. "A computational fluid dynamic study of blood flow through stenosed arteries /." Title page, table of contents and summary only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09pha5808.pdf.

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25

Geoghegan, Patrick Henry. "In Vitro Experimental Investigation Into the Effect of Compliance on Models of Arterial Hemodynamics." Thesis, University of Canterbury. Mechanical Engineering, 2012. http://hdl.handle.net/10092/7529.

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Compliant (flexible) structures play an important role in several biofluid problems including flow in the lungs, heart and arteries. Atherosclerosis is a vascular disease which causes a remodelling of the arterial wall causing a restriction (stenosis) by thickening the intima and the formation of vascular plaque by the deposit of fatty materials. This remodelling alters the compliance of the artery stiffening the arterial wall locally. A common location for this to occur is in the carotid artery which supplies blood to both the brain and the face. It can lead to complete occlusion of the a

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26

Bark, David Lawrence Jr. "The hemodynamics during thrombosis and impact on thrombosis." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37258.

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Atherothrombosis can induce acute myocardial infarction and stroke by progressive stenosis of a blood vessel lumen to full occlusion. The goal of this research is to determine what shear rates are pertinent to an occluding blood vessel, the rate of thrombus growth relative to wall shear rates, and to develop a predictive model for estimating length of time to thrombus occlusion for a given atherosclerotic lesion. Computational studies of severely stenotic idealized vessels were performed to investigate the wall shear rates that may exist. The study shows that maximum shear rates in severe sh

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27

Hong, Say Yenh. "Fluid structure interaction modeling of pulsatile blood flow in serial pulmonary artery stenoses." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112571.

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Motivated by the physiological phenomena of collapse and flow limitation for a serial pulmonary artery stenosis, we investigated the three-dimensional influence of spatial configuration on the wall motion and hemodynamic. Our numerical study focused on the effect of two geometrical parameters: the relative distance and the angular orientation between the two stenoses. The collapse of a compliant arterial stenosis may cause flow choking, which would limit the flow reserve to major vital vascular beds such as the lungs, potentially leading to a lethal ventilation-perfusion mismatch. Flow through

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28

Mendl, Nadine. "Offene und interventionelle Revaskularisation von isolierten und kombinierten Stenosen der supraaortalen Arterien." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-125550.

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29

Li, Mingxiu. "Numerical simulation of blood flow and vessel wall stresses in stenosed arteries." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/12415.

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A flow-wall coupled model is developed by externally coupling of the CFD (Computational Fluid Dynamics) package FLUENT and the FEM (Finite Element Method) package ABAQUS using a MATLAB script. This model is used to study the flow and stress field for idealised stenosed arteries. The impedance of the stenosis is estimated by an LCR model and the boundary conditions are derived from a 1D transmission line model. Studies on localized stiffness for straight and mild stenosed arteries showed that the localized stiffness has a negligible effect on the pressure, local velocity magnitude and was wall

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30

Papadopoulos, Konstantinos. "Flow effect on thrombus formation in stenosed coronary arteries : a computational study." Thesis, City University London, 2015. http://openaccess.city.ac.uk/13497/.

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Thrombotic complications often occur in stenosed coronary artery, causing permanent damage and even death. Although the exact factors and events leading to thrombus formation are not entirely known, the local rheological conditions as well as the different tendency for clotting of the blood of each individual are considered to have an important role both in progress of the disease and the relevant complications. Recently a statistical correlation between the exact location of the stenosis and the evolution of the disease has been reported [1]. In this work we investigated whether this connecti

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31

Larson, Blake E. "Magnetic resonance imaging based percent stenosis and pressure drop measurements in an aortic coarctation model." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/15976.

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32

Kehoe, Anthony. "Coherent and random apparent stresses in periodically unsteady flow." Diss., Georgia Institute of Technology, 1990. http://hdl.handle.net/1853/16732.

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33

Siegel, John Mather Jr. "Magnetic resonance imaging of flow through a stenosis : accuracy of angiography and phase velocity measurements." Diss., Georgia Institute of Technology, 1994. http://hdl.handle.net/1853/17626.

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34

Oshinski, John N. "Use of magnetic resonance imaging to evaluate stenotic flows." Diss., Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/18217.

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35

Anglin, Sandra Sophia Charmain. "The role of the local renin-angiotensin system in the development of fibrocellular intimal hyperplasia following balloon catheter-induced injury in the rat." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307441.

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36

Berg, Sebastian [Verfasser], and Andreas [Akademischer Betreuer] Harloff. "3D-Analyse der Blutströmung bei Patienten mit Arteria carotis interna Stenose mittels 3 Tesla MRT." Freiburg : Universität, 2014. http://d-nb.info/1123479305/34.

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37

PANARO, LAURA. "“Stenosi dell’arteria renale – Esperienza di un singolo centro”." Doctoral thesis, Università degli studi di Genova, 2022. https://hdl.handle.net/11567/1099813.

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BACKGROUND - La stenosi dell’arteria renale è presente dall’1% al 5% nelle persone affette da ipertensione arteriosa (1,2) e spesso si associa a vasculopatia periferica e a coronaropatia (3,4), infatti si ritrova nel 18% - 20% dei soggetti sottoposti a coronarografia (5) e nel 35% - 50% dei pazienti sottoposti ad angiografia vascolare periferica per malattia dei grossi vasi addominali o degli arti inferiori (6). I quadri clinici ad essa correlati sono l’ipertensione nefrovascolare e la nefropatia ischemica cronica. La maggior parte dei casi è secondaria a lesioni aterosclerotiche, localizzate

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38

Chen, Xuewen. "A Nonlinear Viscoelastic Mooney-Rivlin Thin Wall Model for Unsteady Flow in Stenosis Arteries." Digital WPI, 2003. https://digitalcommons.wpi.edu/etd-theses/229.

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Severe stenosis may cause critical flow conditions related to artery collapse, plaque cap rupture which leads directly to stroke and heart attack. In this paper, a nonlinear viscoelastic model and a numerical method are introduced to study dynamic behaviors of the tube wall and viscous flow through a viscoelastic tube with a stenosis simulating blood flow in human carotid arteries. The Mooney-Rivlin material model is used to derive a nonlinear viscoelastic thin-wall model for the stenotic viscoelastic tube wall. The mechanical parameters in the Mooney-Rivlin model are calculated from experime

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39

Schumann, René. "Vergleichende immunhistochemische Untersuchung zur T-Zell- und Makrophageninfiltration symptomatischer und asymptomatischer Stenosen der Arteria carotis interna." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964822504.

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40

Khalid, Naciri Jaâfar. "Modelisation d'ecoulements instationnaires en conduites deformables : applications aux ecoulements arteriels." Toulouse 3, 1988. http://www.theses.fr/1988TOU30052.

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41

Bergman, Harris L. "Knowledge-based magnetic resonance angiography." Diss., Georgia Institute of Technology, 1999. http://hdl.handle.net/1853/18247.

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42

Schriek, Carsten. "Untersuchungen zur Interaktion von Leukozyten und Thrombozyten bei Patienten mit arteriosklerotischen Stenosen der hirnversorgenden Arterien." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=97169155X.

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43

Heldmaier, Lynn Vera Ilona [Verfasser]. "Langzeitprognose nach Angioplastie und Stentung von Stenosen intrakranieller Arterien / Lynn Vera Ilona Heldmaier geb. Hoberg." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1217249346/34.

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44

Beneli, Cristina Tonin. ""Hiperplasia intimal arterial decorrente de um modelo experimental de estenose aórtica intrínseca: estudo morfológico, morfométrico e ultraestrutural"." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/17/17143/tde-22092006-114410/.

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O objetivo do presente trabalho foi avaliar a morfologia e a ultraestrutura da hiperplasia intimal arterial decorrente de um modelo de estenose aórtica experimental, através da inserção de um pino de acrílico no orifício da artéria renal esquerda. Realizamos um estudo morfológico e ultraestrutural em 64 ratos Wistar, machos, com peso médio de 250 g, divididos em 4 subgrupos de acordo com o dia da eutanásia (1, 7, 15 e 30 dias de pós-operatório). O segmento da aorta envolvendo o pino foi retirado e estudado com diferentes protocolos para: microscopia óptica de alta resolução, microscopia eletrô

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45

Karri, Satyaprakash Babu. "Laminar and Transitional Flow disturbances in Diseased and Stented Arteries." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/28880.

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Cardiovascular diseases (CVD) are the number one causes of death in the world. According to the world Health Organization (WHO) 17.5 million people died from cardiovascular disease in 2005, representing 30 % of all global deaths . Of these deaths, 7.6 million were due to heart attacks and 5.7 million due to stroke. If current trends are allowed to continue, by 2015 an estimated 20 million people will die annually from cardiovascular disease. The trends are similar in the United States where on an average 1 person dies every 37 seconds due to CVD. In 2008 an estimated 770,000 Americans will exp

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46

Kunte, Gerolf [Verfasser]. "Morphologische Plaqueunterschiede von symptomatischen Stenosen der Arteria carotis interna bei Patienten mit embolischem und hämodynamischem Schlaganfallmechanismus / Gerolf Kunte." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1026264766/34.

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47

Loizos, Savvas. "Duplex ultrasound assessment of carotid arterial atherosclerotic disease : investigation of direct stenosis measurement methods and image analysis for vulnerable plaque identification." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9764.

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Purpose: Ultrasound assessment of carotid disease is currently based on stenosis haemodynamic effects. The accuracy of direct stenosis measurement remains unclear, while research on atherosclerosis suggests identification of other plaque characteristics beyond size. The aim of the study is to investigate whether direct stenosis measurement and plaque ultrasound image analysis could potentially be used for more accurate diagnostic investigation. Method and material: Eighty-seven patients with cardiovascular disease had a carotid duplex ultrasound scan and velocity and B-mode measurements data w

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48

Roth, Claudia. "Wertigkeit der Digitalen Subtraktionsangiographie (DSA) gegenüber der Magnetresonanzangiographie (MRA) in der Diagnostik der hirnversorgenden Halsgefässe." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2004. http://dx.doi.org/10.18452/15019.

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Das Ziel: der Arbeit war die Überprüfung der Aussagekraft der MRA in time-of-flight-technique der Arteria caroits bei 1,0 Tesla im Vergleich zur intaarteriellen DSA und der Wertigkeit in der Einsatzfähigkeit in der klinischen Routine bei der Diagnostik von Carotisstenosen. 101 Patienten wurden zur Abklärung einer Stenose der Arteria carotis vergleichend mittels TOF-MRA und i.a. DSA der Arteriae carotis untersucht. Morphologische Veränderungen wurden für sämliche Gefässe erfasst, wobei die Stenosen der Arteriae carotis entsprechend den NASCET-Kriterien graduiert wurden (geringgrade, mittelgrad

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49

Heinze, Marlene Kathrin Friederike [Verfasser], and Götz [Akademischer Betreuer] Thomalla. "Einfluss von hochgradigen Arteria carotis interna Stenosen auf zerebrale Perfusion und Kognition / Marlene Kathrin Friederike Heinze ; Betreuer: Götz Thomalla." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2019. http://d-nb.info/1179916050/34.

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50

Flügel, Johannes [Verfasser]. "Stenosen und Plaquemorphologie der Arteria carotis: Evaluierung der 64-Zeilen-Multidetektor-Computertomographie im Vergleich zur Digitalen Subtraktionsangiographie / Johannes Flügel." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2010. http://d-nb.info/1028493967/34.

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