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1

Skvortsov, V. V., A. V. Leskova, and A. V. Kiseleva. "Asthenovegetative syndrome after COVID-19 in the practice of a family doctor." Spravočnik vrača obŝej praktiki (Journal of Family Medicine), no. 2 (January 31, 2023): 31–39. http://dx.doi.org/10.33920/med-10-2302-04.

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This study assesses and systematizes the signs of asthenovegetative syndrome (AVS) in patients who had COVID-19 a month ago. The survey was completed by 44 respondents aged 20 to 80 years. According to the results of the survey, the most common manifestation of asthenovegetative syndrome is weakness. The respondents also noted emotional disturbances, decreased attention, sleep disturbances, pain in the joints and muscles, weight loss, and headache. To assess the dynamics of the studied manifestations, a survey was conducted using the Vein's autonomic dysfunction scale. In 93.1 % of the respond
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Kiryutkina, A. P., N. B. Migacheva, T. I. Kaganova, V. V. Burmistrov, and A. S. Ginzburg. "Age aspect of the course of new coronavirus infection in the acute and post-Covid in children." Medical Herald of the South of Russia 15, no. 2 (2024): 90–100. http://dx.doi.org/10.21886/2219-8075-2024-15-2-90-100.

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Objective: studying the influence of various factors on the course and outcomes of COVID-19 in children of different ages, to determine patient management tactics.Materials and methods: the article presents the results of a retrospective assessment of the course of COVID-19 in 89 children observed in clinics of Samara city. A comparative analysis of the course of COVID-19 and post-COVID in children of different ages was carried out. Statistical analysis was carried out by IBM SPSS Statistica 25, p<0.05 was considered the criterion for significance.Results: the severity of COVID-19 was indep
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Гутнова, Svetlana Gutnova, Тадтаева, and Diana Tadtaeva. "The study of systemic microcirculation and main clinical syndromes under the influence of combined and intravenous methods of laser therapy while chronic pancreatitis." Vladikavkaz Medico-Biological Bulletin 20, no. 29 (2014): 42–47. http://dx.doi.org/10.12737/11823.

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The purpose of this study was to investigate the systemic microcirculation and main clinical syndromes under the influence of combined and intravenous methods of low-intensive laser therapy (LILT) in patients with chronic pancreatitis (ChP) in acute phase. 123 patients aged 36-77 years old were examined and divided into 2 groups: the experimental (78 patients) and the control group (45 patients). 30 men were in addition surveyed who composed the healthy group. The experimental group has had a complex drug and laser therapy of various therapeutic techniques: I subgroup – intravenous laser blood
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Liubyshkina, AV V., MV V. Stulova, AA A. Suzdaltsev, DYu Yu Konstantinov, and LL L. Popova. "CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF HEMORRHAGIC FEVER WITH RENAL SYNDROME IN THE SAMARA REGION." Science and Innovations in Medicine 3, no. 3 (2018): 30–34. http://dx.doi.org/10.35693/2500-1388-2018-0-3-30-34.

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Aim - to study clinical and epidemiological characteristics features of hemorrhagic fever with renal syndrome. Materials and methods. A retrospective comparative analysis of the results of clinical and epidemiological examination of HFRS patients was carried out in two groups: with moderate (n=106) and severe (n=22) forms of the disease, who were hospitalized in the clinic of infectious diseases of Samara State Medical University in 2017. Results. A significant predominance of the air-dust pathway of infection in severe forms of the disease was revealed. Most patients were young men in both gr
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Kokovina, Yu, E. Yu Pavlova, and E. A. Antonova. "“Hepatogenic diabetes” is an old term and new meaning." Meditsinskiy sovet = Medical Council, no. 7 (May 29, 2020): 19–24. http://dx.doi.org/10.21518/2079-701x-2020-7-19-24.

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Introduction. Today, non-alcoholic fatty liver disease (NAFLD) is increasingly associated with the presence or risk of developing type 2 diabetes (D2). The term “hepatogenic diabetes”, proposed to refer to SD2 in patients with cirrhosis of the liver (CP), has acquired a new meaning, since this combination is of growing interest. The authors analyzed the current literature and summarized data on the pathogenesis, risk factors, and possible therapy of NAFLD.Objective: to evaluate the effectiveness of L-ornithine-L-aspartate (HEPA-Merz, Merz Pharma GmbH & Co) in combination with biguanides in
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Levchin, Artem M., Irina B. Ershova, and Yulia V. Glushko. "Features of the Psychoemotional State of Younger Schoolchildren in the Period of Acute Respiratory Viral Infection Convalescence." HERALD of North-Western State Medical University named after I.I. Mechnikov 17, no. 1 (2025): 89–97. https://doi.org/10.17816/mechnikov646488.

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BACKGROUND: High incidence of acute respiratory viral infections In primary school children, associated with a combination of factors such as critical age periods and lifestyle changes with a redistribution of psychophysical loads, requires a more detailed study of the psycho-emotional state of children during the period of convalescence after acute respiratory viral infection. AIM: To asses the psychoemotional state of primary school-age children within six months after acute respiratory viral infections, taking into account its severity and form. METHODS: 430 children of 7–9 years of age enr
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Nykytyuk, S. O., I. M. Tsimbalyuk, M. V. Dolynna, N. Ya Bodnarchuk-Sokhatska, and Y. P. Polyhach. "Fatigue syndrome after a viral illness. Post COVID-19 exanthema infection. Ichthyosis of the skin of the feet. (Clinical case)." Modern pediatrics. Ukraine, no. 5(125) (September 30, 2022): 135–40. http://dx.doi.org/10.15574/sp.2022.125.135.

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The COVID-19 pandemic has posed many challenges to the medical community, a number of which will remain in the near future. Analysis of clinical cases helps to identify problems, to plan future research, which can change the understanding of the consequences of the disease. As the first year of the pandemic progresses, there is a better understanding of the pathophysiology of the virus and the varied results of imaging COVID-19 in affected organs, which is crucial for improving the treatment of this complex disease and improving health outcomes. It is described a clinical case of exanthema in
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Drozdova, M. V., S. N. Larionova, and E. V. Tyrnova. "Features of preoperative diagnosis of chronic lymphoproliferative syndrome of ENT organs in young children." Meditsinskiy sovet = Medical Council, no. 23 (January 19, 2023): 343–48. http://dx.doi.org/10.21518/2079-701x-2022-16-23-343-348.

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Introduction. To determine the tactics of management of chronic lymphoproliferative syndrome in young children, a comprehensive examination is necessary. Herpesvirus infection (HVI) plays an important role in the etiology of hypertrophy of lymphoid formations of the pharynx.Purpose. To evaluate the results of preoperative diagnosis of chronic lymphoproliferative syndrome in children in early childhood.Materials and methods. In 96 patients aged 1 to 3 years 11 months with lymphoproliferative syndrome more than 3–6 months, endoscopy, otomicroscopy, impedance, ultrasound examination of abdominal
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Хабарова, Алина Валерьевна, та Яна Анатольевна Соцкая. "СОСТОЯНИЕ МИКРОБИОТЫ ТОЛСТОЙ КИШКИ У БОЛЬНЫХ ХРОНИЧЕСКИМ ВИРУСНЫМ ГЕПАТИТОМ В". University therapeutic journal 6, № 3 (2024): 125–32. https://doi.org/10.56871/utj.2024.50.73.013.

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Введение. Гепатобилиарная система неразрывно взаимодействует с микробиотическим биоценозом кишечника в процессах детоксикации, метаболизма, формирования и регуляции общего и местного иммунитета. Цель исследования — изучение микробного состава толстой кишки у больных хроническим вирусным гепатитом В, сочетанным с дисбиозом кишечника, в динамике в ходе лечения. Материалы и методы. Было обследовано 72 пациента с диагнозом «хронический вирусный гепатит В» (ХВГВ) с признаками нарушения популяционного содержания микробиоты толстой кишки, распределенных на две группы. Диагноз ХВГВ подтверждали посред
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10

Шалькевич, Л. В., И. В. Жевнеронок, and М. М. Костеневич. "Features of Neurological Manifestations of Post-COVID Syndrome in Children: A Literature Review." Педиатрия. Восточная Европа 12, no. 1 (2024): 78–85. http://dx.doi.org/10.34883/pi.2024.12.1.007.

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Статья посвящена проблеме последствий перенесенной инфекции COVID-19 у детей. Рассмотрены основные факторы риска развития long COVID-19 у детей: возраст (чаще постковидный синдром развивается у детей старшего возраста); наличие в анамнезе аллергических реакций, неврологических заболеваний, патологии органов дыхания; избыточный вес (ожирение); тяжелое течение COVID-19. Приводится определение постковидного синдрома, выделены его основные проявления у детей: преимущественно функциональный характер клинических проявлений; преобладание в структуре неврологических нарушений головных болей и астениза
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11

Ageykin, A. V., D. V. Usenko, A. V. Gorelov, et al. "Dynamics of post-COVID asthenia: review." Сибирский научный медицинский журнал 44, no. 6 (2025): 6–16. https://doi.org/10.18699/ssmj20240601.

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Novel coronavirus infection (COVID-19) is a highly contagious respiratory disease caused by the SARS-CoV-2 coronavirus. COVID-19 is known to affect both the respiratory, digestive, excretory, and nervous systems. The incidence of chronic effects of the novel coronavirus infection is now on the rise. This paper is aimed to review the epidemiology, pathogenesis and components of post-COVID asthenia. Material and methods. Sixty-three references published between 2005 and 2023 and indexed in the PubMed, CyberLeninka, Russian Citation Index, Semantic Scholar, and Google Scholar databases were inclu
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12

Khaitovych, M. V., and D. V. Turchak. "JILBER’S SYNDROME: CLINICAL AND PHARMACOLOGICAL ASPECTS. Review." Medical Science of Ukraine (MSU) 16, no. 4 (2020): 58–64. http://dx.doi.org/10.32345/2664-4738.4.2020.9.

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Relevance. At present, the metabolism of drugs in patients with Gilbert's syndrome will be actively studied, as it may be associated with both the risk of dose-dependent adverse reactions and treatment ineffectiveness.
 Objective: to summarize the information of various authors on the peculiarities of the use of drugs in patients with Gilbert's syndrome.
 Methods. Analysis of scientific publications in the international electronic scientometric database PubMed by keywords. Search depth - 10 years (2010-2019).
 Results. Gilbert’s syndrome is observed in 3-10% of the population an
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13

Derbak, Mariya A., Oksana T. Hanych, Taras M. Ganich, et al. "The Effectiveness of the Gastro-esophageal Reflux Disease Treatment in Persons who have Completed Successful Chronic Hepatitis C Antiviral Therapy at the Rehabilitation Stage." Acta Balneologica 64, no. 4 (2022): 333–36. http://dx.doi.org/10.36740/abal202204110.

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Aim: To assess the effectiveness of the physiopharmacological treatment of GERD in persons who successfully completed a full course of CHC therapy with direct antiviral drugs no more than 6 months ago. Materials and Methods: 67 people with GERD who completed a course of CHC therapy with direct antiviral drugs no more than 6 months ago were under observation. The patients were divided into: 1 group (n=20) – received rabeprazole 20 mg in the morning 40 minutes before meals, 2 group (n=23) – rabeprazole 20 mg in combination with taking mineral water “Polyana Kvasova” according to the proposed sch
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14

Rusinova, Dina S., Tatyana M. Vasil’eva, Alexey S. Bezymyanny, and Andrey V. Starshinin. "Analysis of Employee’s Working Capacity in Children’s City Outpatient’s Clinic №133 of Moscow City Health Department after COVID-19." Pediatric pharmacology 18, no. 6 (2021): 507–14. http://dx.doi.org/10.15690/pf.v18i6.2348.

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The issues of long-lasting violations of physical and mental health among employees of Children’s City Outpatient’s Clinic №133 of Moscow City Health Department after COVID-19, as well as they effect on work quality and efficacy, and in some cases loss of any interest to work got us thinking about the features of post-COVID-19 syndrome and and forced us to analyze the prevalence and duration of various symptoms in employees. The protocol for this observational study was approved by the Moscow City Independent Ethics Committee. Developed questionnaires with questions both on the course of COVID
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Matyakubova, Oysha Urinovna, Ikrom Axmedjonovich Artiqov, Sevara Salibayevna Ibodullayeva, Dinora Odilbekovna Razzoqberganova, and Mexriniso Qaxramon qizi Rajabova. "COVID-19 INFECTION AND MENTAL DISORDERS." Multidisciplinary Journal of Science and Technology 5, no. 5 (2025): 900–905. https://doi.org/10.5281/zenodo.15484076.

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In today's world, it is rare for a person not to have encountered a coronavirus infection. The symptoms that all individuals who have had it experience are well-known, including fever, cough, nasal discharge, difficulty breathing, and loss of smell. The impact of the coronavirus infection is not only related to its severe progression and risk of death, but also to its negative effects on human health. Patients who have undergone COVID-19 often face many negative consequences, and among the most prominent are mental, emotional, cognitive, and vegetative issues that significantly affect quality
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Mukhamadieva, V. N., N. G. Shamsutdinova, R. Z. Abdrakipov, R. G. Mukhina, and D. I. Abdulganieva. "Postcovid syndrome in patients with rheumatic diseases." Russian Medical Inquiry 7, no. 7 (2023): 452–59. http://dx.doi.org/10.32364/2587-6821-2023-7-7-8.

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Aim: to study the incidence and duration of postcovid manifestations in patients with rheumatic diseases (RD), as well as the RD course patterns in the postcovid period. Patients and Methods: 271 patients (mean age 56 [46; 65] years) were included in the study: with a diagnosis of rheumatoid arthritis (RA) — 186 (68.6%) patients, with ankylosing spondylitis (SpA) — 46 (16.9%), with psoriatic arthritis — 38 (14%) patients who had previously suffered COVID-19. The presence of postcovid syndrome (PCS) was determined 3, 6, 9 or 12 months after acute COVID-19. An in-depth medical check- up question
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Manzhalii, E. G. "A clinical case of fatty liver disease. How the new nomenclature can be applied in practice." Modern Gastroenterology, no. 5 (October 31, 2023): 50–55. http://dx.doi.org/10.30978/mg-2023-5-50.

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Metabolic dysfunction‑associated steatotic liver disease (MASLD) is an urgent problem, as this condition is diagnosed in about 35% of the world’s population. Manifestations of metabolic dysfunction in MASLD include excessive body weight (abdominal obesity is the most dangerous), manifestations of dyslipidemia, hepatomegaly, signs of diabetes, arterial hypertension, and moderate alcohol consumption (> 20 g/30 g of alcohol per day in women and men, respectively). According to a new meta‑analysis, MASLD significantly increases the risk of cardiovascular, metabolic, oncological and reproductive
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Alikina, Inga N., Oleg V. Dolgikh, and Olga A. Kazakova. "Peculiarities of the Expression of immune mediators under aerogenic exposure of aluminum." Hygiene and sanitation 99, no. 11 (2020): 1203–10. http://dx.doi.org/10.47470/0016-9900-2020-99-11-1203-1210.

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Introduction. Chemical admixtures, including those containing aluminum contaminate the R.F. territory environment. There is a well-proven dependence between hygienic factors and population health. Both facts call for developing scientifically substantiated sanitary recommendations for diagnostics and prevention that should involve applying up-to-date critical technologies, including research on proteins acting as immune modulators. Material and methods. We performed a diagnostic examination and comparatively analyzed the health of children living on territory under the ambient air exposure to
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19

Yastrebova, E. B., O. E. Chernova, A. M. Kalyshenko, and G. A. Vertogradova. "Chronic hepatitis C in children with HIV infection: disease phenotype and efficacy of antiviral therapy." Infekcionnye bolezni 19, no. 2 (2021): 52–58. http://dx.doi.org/10.20953/1729-9225-2021-2-52-58.

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Objective. To analyze the course of chronic hepatitis C (CHC) and efficacy of its treatment in children with HIV infection. Patients and methods. This study included 29 children aged 12 to 17 years (mean age 15.1 ± 0.2 years) with perinatal HIV infection and CHC. HIV stages were distributed as follows: stage 4A in 24 individuals (82.8%), stage 4B in 4 individuals (13.8%), and stage 4B in 1 individual (3.4%). All 29 patients received antiretroviral therapy. The distribution of children by HCV genotypes was as follows: 1a in one child (3.4%), 1b in 12 children (41.4%), and 3a in 16 children (55.
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Kulagina, A. P., A. A. Suzdaltoev, L. M. Zotova, N. Z. Nausheev, and R. B. Oganyan. "IX0DIC TICK-BORNE B0RRELI0SIS IN THE SAMARA REGION." Aspirantskiy Vestnik Povolzhiya 19, no. 1-2 (2019): 91–94. http://dx.doi.org/10.17816/2072-2354.2019.194.91-94.

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The article is devoted to the identification of regional peculiarities of tick-borne borreliosis in the Samara region. Over the past 10 years, the Samara region has seen an increase in the number of cases of ticks sucking by 2.5 times, as well as an increase in contamination of ixodic ticks by Borrelia. Infection of patients with tick-borne borreliosis was observed not only in forest area, but also in the city. Cases of the disease were recorded from May to October. In this region asthenovegetative syndromes, exanthema, fever and regional lymphadenitis were revealed in patients diagnosed with
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21

Karpenko, D. G., V. V. Dryutova, V. N. Larina, and E. V. Fedorova. "Clinical observation of a middle-aged patient with a masked course of pancreatic necrosis observed on an outpatient basis." Experimental and Clinical Gastroenterology, no. 8 (January 18, 2023): 198–205. http://dx.doi.org/10.31146/1682-8658-ecg-204-8-198-205.

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Objective. On the example of a clinical case, the difficulties of timely diagnosis of acute pancreatitis are considered. Main points. Acute pancreatitis is an actual problem of modern medicine due to its wide prevalence and high mortality rates. A clinical observation of a 48-year-old patient with dyspeptic complaints and intestinal manifestations is presented. Conclusion. The presented clinical case illustrates not only the difficulty of timely diagnosis of acute pancreatitis, but also confirms that patients with existing pain, dyspeptic and asthenovegetative syndromes after a viral intestina
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Brazhenko, O. N., and A. I. Loschakova. "Assessment of the state of autonomic dysfunction in patients with tuberculosis of the respiratory system and in combination with HIV infection in modern conditions." HIV Infection and Immunosuppressive Disorders 15, no. 4 (2024): 47–52. http://dx.doi.org/10.22328/2077-9828-2023-15-4-47-52.

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The autonomic nervous system (ANS) is an important part of the human nervous system responsible for regulating internal organs and maintaining the internal environment of the body. Adequate functioning of the ANS supports homeostasis is the internal stability of the body and regulates many functions in it, such as cardiac activity, breathing, etc. TB-related stress and inflammation affect have influence at the balance of sympathetic and parasympathetic activity. Affecting the work of the peripheral nervous system, it becomes possible to influence at the system of homeostasis of the body throug
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Javadzade, V. N. "ABOUT VIRAL HEPATITIS A." "The Medicine and Science" scientific-practical journal named after A.Aliyev 4, no. 30 (2023): 81–84. http://dx.doi.org/10.61775/2413-3302.v4i30.12.

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The article discusses the general features of viral hepatitis A, which is widespread among children and adolescents. Viral hepatitis A is an acute infectious disease transmitted by the fecal-oral mechanism, which is mostly asymptomatic and usually results in recovery. The causative agent is enterovirus of type 72 related to the family of Picarnoviridae, genus heparnovirus. It is an Anthroponosis disease. It spreads through water, food, and household - contact ways. The incubation period is in average 15-20 days. Catarrhal, dyspeptic, asthenovegetative, arthralgic and mixed syndromes occur in t
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Lukashik, S. P., I. A. Karpov, and O. V. Krasko. "Hepatitis C Infections with Cryoglobulinemia: Features and Symptoms." Doctor.Ru 20, no. 4 (2021): 26–32. http://dx.doi.org/10.31550/1727-2378-2021-20-4-26-32.

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Study Objective: To study the incidence of cryoglobulinemia (CGE) in chronic hepatitis C infection (hepatitis C infection) and to analyse the characteristics of chronic hepatitis C infection with CGE in Belarusian patients. Study Design: Open non-randomised observational study. Materials and Methods. The study included 773 patients with chronic hepatitis C infection (in Minsk). The patients had their anti-hepatitis C antibodies, chronic hepatitis C RNA and virus genotype measured; blood cryoglobulins identified; demographic and epidemiological data collected; and complete blood assay and bioch
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Popova, L. L., D. Yu Konstantinov, Ye A. Strebkova, et al. "Clinico-laboratory and immunological characteristics of patients with compensated cirrhosis of the liver in the outcome of chronic hepatitis C on the background of treatment with a direct antiviral drug paritrapeprir/ritonavir/ombitasvir/ dasabuvir." Journal Infectology 10, no. 4 (2018): 42–47. http://dx.doi.org/10.22625/2072-6732-2018-10-4-42-47.

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Goal. Paritrapeprir / ritonavir / ombitasvir / dasabuvir on the clinical and laboratory parameters, including thesubpopulation composition of lymphocytes, in patients with compensated cirrhosis in the outcome of chronic hepatitis C. Materials and methods. The study included patients with compensated liver cirrhosis class A (no more than 6 on the Child – Turcotte – Pugh scale), in the outcome of chronic hepatitis C, genotype 1b (group 1, n = 28). The comparison group (group 2, n = 25) consisted of patients comparable in terms of gender and main study parameters, not receiving antiviral therapy.
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Batskov, S. S., and D. I. Inzhevatkin. "New approaches to correction of hyperammonemia in patients with non-alcohol steatohepatitis – liquidators of consequences of the accident at Chernobyl APP and personnel of the Federal Fire Service of the EMERCOM of Russia." Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations, no. 3 (September 28, 2018): 26–34. http://dx.doi.org/10.25016/2541-7487-2018-0-3-26-34.

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Relevance.The relevance of this study is determined by the need to correct hyperammonemia in patients with diffuse liver diseases at the pre-cirrhotic stage, since elevated levels of ammonia in the serum have toxic effects on the central nervous system, with the development of hepatic encephalopathy.Intention.To evaluate current medication options for correction of hyperammonemia in chronic non-alcoholic steatohepatitis in the liquidators of the consequences of the accident at the Chernobyl nuclear power plant (NPP) and personnel of the Federal Fire Service (FFS) of the Emercom of Russia.Metho
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Spivak, E. M., O. M. Manyakina, and I. S. Akkuratova. "Peculiar features of inflammatory process in gastric mucosa with different character of its bacterioviral infection in adolescents with chronic gastritis." Perm Medical Journal 35, no. 6 (2018): 10–15. http://dx.doi.org/10.17816/pmj35610-15.

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Aim. To characterize the inflammatory process in gastric mucosa among adolescents with chronic gastritis in different variants of its bacterioviral infection.
 Materials and methods.Clinicoanamnestic, laboratory, endoscopic and morphological examination of 200 adolescents (age range 12–18 years) with chronic gastritis was carried out. In all patients, clinicoanamnestic data, standard laboratory study, esophagogastroduodenoscopy, gastrobiopsy followed by morphological analysis with visual analogue scale were assessed. According to the results of examination, all adolescents were divided in
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Krivoruchko, Irina Vladimirovna, and Mikhail Georgievich Paraskevopulo. "Investigation of clinical and epidemiological features of Opisthorchis felineus invasion in Voronezh region." Sanitarnyj vrač (Sanitary Doctor), no. 1 (2022): 7–11. http://dx.doi.org/10.33920/med-08-2201-01.

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The functioning of a natural focus of opisthorchiasis with a high level of epidemiological risk has been established within the borders of the Voronezh region, which forms the social and medical significance of the invasion. The aim of the study was study the epidemiology of opisthorchiasis and analyze the features of the clinical manifestations of the chronic opisthorchiasis invasion in the natural focus of the Voronezh region. Clinical and epidemiological data, the results of general clinical laboratory studies, as well as parasitological, serological, instrumental studies were analyzed. The
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Makhnitska, Iryna, and Liliia Babinets. "Features of the Clinical Course and Quality of Life in a State with Chronic Pancreatitis and Gastroduodenal Changes." Family medicine. European practices, no. 2 (April 28, 2023): 45–49. http://dx.doi.org/10.30841/2786-720x.2.2023.282493.

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Despite the significant progress in the study of pancreatic gland (PG) pathology, the clinical symptoms and syndromes, as well as assessment of quality of life using the SF-36 and GSRS questionnaires in patients with chronic pancreatitis (CP) in combination with comorbid pathology of the organs of the gastroduodenal zone (GDZ) remain insufficiently studied and substantiated. The objective: to analyze the clinical symptoms and assessment of quality of life using the SF 36 and GSRS questionnaires in the comorbidity of chronic pancreatitis with H. pylori-associated chronic gastritis. Materials an
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Makhnitska, Iryna, and Liliia Babinets. "Features of the Clinical Course and Quality of Life in a State with Chronic Pancreatitis and Gastroduodenal Changes." Family Medicine. European Practices, no. 2 (April 28, 2023): 45–49. https://doi.org/10.30841/2786-720X.2.2023.282493.

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Despite the significant progress in the study of pancreatic gland (PG) pathology, the clinical symptoms and syndromes, as well as assessment of quality of life using the SF-36 and GSRS questionnaires in patients with chronic pancreatitis (CP) in combination with comorbid pathology of the organs of the gastroduodenal zone (GDZ) remain insufficiently studied and substantiated. <strong>The objective:</strong>&nbsp;to analyze the clinical symptoms and assessment of quality of life using the SF 36 and GSRS questionnaires in the comorbidity of chronic pancreatitis with H. pylori-associated chronic g
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Savchenko, A. A., E. V. Kasparov, S. A. Borisov, A. A. Masterova, and Alexander G. Borisov. "Evaluation of the effectiveness of detoxification in the immunorehabilitation of cancer patients." Cytokines and inflammation 19, no. 1-4 (2023): 61–68. http://dx.doi.org/10.17816/ci2022221-4-11.

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Purpose. Evaluation of the effectiveness of detoxification using enterosorbents in the immunorehabilitation of cancer patients.&#x0D; Materials and methods. 87 patients with metastatic forms of solid tumors of various localizations with metastatic lesions were examined. The patients were divided into 2 groups: study group (41 patients who received detoxification therapy in addition to standard therapy) and comparison group (46 patients who received only standard therapy). The effectiveness of therapy with these drugs was evaluated after one month by assessing clinical and immunological paramet
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Konstantinov, D. Yu, L. L. Popova, S. Yu Vasilev, and M. A. Popilov. "Clinical experience of using Polysorb in complex pathogenetic therapy of chronic hepatitis C with severe liver fibrosis." Meditsinskiy sovet = Medical Council, no. 8 (June 9, 2024): 82–88. http://dx.doi.org/10.21518/ms2024-191.

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Introduction. Violation of metabolic processes in the gastrointestinal tract in patients with chronic hepatitis C (HCV) leads to the accumulation of toxic metabolic products in the intestine, negatively affecting both the balance of the microbiota and the functional state of hepatocytes. The sorption of toxins released by opportunistic anaerobic bacteria contributes to the restoration of the population of bifidobacteria and lactobacilli, which has a beneficial effect on the functional state of the liver.Aim. To evaluate the clinical and laboratory efficacy and safety of Polysorb as part of com
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Венцловайте, Н. Д., Л. Г. Горячева, В. А. Грешнякова, Н. А. Ефремова, and И. В. Шилова. "Viral Hepatitis C in Children: A Retrospective Analysis and Future Prospects." Клиническая инфектология и паразитология, no. 2 (November 4, 2021): 208–18. http://dx.doi.org/10.34883/pi.2021.10.2.027.

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Введение. Хронический гепатит С (ХГС) занимает лидирующую позицию среди всех хронических гепатитов. Около 71 миллиона человек в мире инфицированы вирусом гепатита С (ВГС), среди них, по разным оценкам, от 2,1 до 5 млн составляют дети до 15 лет. В большинстве случаев заболевание в детском возрасте протекает бессимптомно, однако с возрастом повышается риск развития фиброза и связанных с ним осложнений, что требует динамического контроля и своевременного назначения противовирусной терапии. Цель исследования. Определить эпидемиологические особенности и характер течения вирусного гепатита С у детей
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Kiryanova, Vera V., and Alla V. Gordeychuk. "Photochromotherapy in comprehensive treatment of children with chronic gastroduodenitis." Russian Journal of Physiotherapy, Balneology and Rehabilitation 24, no. 1 (2025). https://doi.org/10.17816/rjpbr628819.

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BACKGROUND: Photochromotherapy methods that restore impaired body functions provide a basis for their inclusion in the comprehensive treatment of children with chronic gastroduodenitis. AIM: To develop and justify the use of narrow-band optical radiation at 650 nm and 540 nm as part of comprehensive treatment of chronic gastroduodenitis in children. MATERIALS AND METHODS: An open, randomized, controlled prospective study was conducted, including 80 children with chronic gastroduodenitis. Using simple randomization, the children were divided into three groups. The first group (n=30) received na
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Antoniv, А. А. "PECULIARITIES OF THE CLINICAL COURSE OF NON-ALCOHOLIC STEATOHEPATITIS AND STEATOSIS OF THE LIVER AT COMORBID WITH CHRONIC KIDNEY DISEASE I-III STAGE." Clinical & experimental pathology 20, no. 1 (2021). http://dx.doi.org/10.24061/1727-4338.xx.1.75.2021.1.

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Purpose - to establish clinical peculiarities of the clinical course of the liver nonalcoholic steatosis (NALS) and steatohepatitis (NASH) at comorbidity with chronickidney disease (CKD) (chronic pyelonephritis) I-III stage.Material and methods. We have examined 444 patients: 84 patients with non-alcoholicadipose liver disease (NAALD) with obesity I degree (I group), containing 2 subgroups -32 patients with NALS and 52 patients with NASH; 270 NAALD patients with comorbidobesity I degree and CKD I-III stages (group 2), including 110 patients with NALS and160 patients with NASH. The control grou
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Khaitovych, M. V., and D. V. Turchak. "JILBER’S SYNDROME: CLINICAL AND PHARMACOLOGICAL ASPECTS. Review." Medical Science of Ukraine (MSU) 16, no. 4 (2020). http://dx.doi.org/10.32345/2664-4738.4.2020.9.

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Relevance. At present, the metabolism of drugs in patients with Gilbert's syndrome will be actively studied, as it may be associated with both the risk of dose-dependent adverse reactions and treatment ineffectiveness.&#x0D; Objective: to summarize the information of various authors on the peculiarities of the use of drugs in patients with Gilbert's syndrome.&#x0D; Methods. Analysis of scientific publications in the international electronic scientometric database PubMed by keywords. Search depth - 10 years (2010-2019).&#x0D; Results. Gilbert’s syndrome is observed in 3-10% of the population an
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"Clinical peculiarities of gastrointestinal symptoms in children with food allergy." Journal of V. N. Karazin Kharkiv National University, Series "Medicine", no. 40 (2020). http://dx.doi.org/10.26565/2313-6693-2020-40-04.

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Introduction. Pediatric allergy problems are widely spread among children of almost all age groups. Number of cases with combined allergic a digestive disorders increases and study of gastrointestinal lesions in children with allergies became an urgent medical and social problem. It is based on the increasing frequency of both allergy and pathology of the digestive system, increasing severity of cases and necessity to analyze type of gastrointestinal disorder in children with allergy and correlation among it. Objective. To study the clinical features of gastrointestinal symptoms in children wi
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Tolibov, Farrux Farhodivich. "IMPACT OF CORTICOSTEROID AND IMMUNOSUPPRESSIVE THERAPY ON THE COURSE OF CHRONIC HEPATITIS: RISKS AND PROSPECTS." February 22, 2025. https://doi.org/10.5281/zenodo.14909796.

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<em>Chronic viral hepatitis is an inflammatory dystrophic-proliferative process in the liver, genetically determined by a deficiency of cellular and macrophage immunity, prolonged (more than 6 months), clinically manifested by asthenovegetative and dyspeptic syndromes, persistent hepatosplenomegaly, liver dysfunction, hyperfermentemia and dysproteinaemia.</em>
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G.M., Jeenalieva, Abdykerimova M.M., and Abdikerimov M.M. "FEATURES OF CLINICAL AND LABORATORY MANIFESTATIONS OF CHRONIC HEPATITIS C IN PATIENTS WITH HIV INFECTION, INJECTING DRUG USERS." Natural resources of the Earth and environmental protection, December 4, 2020, 66–69. http://dx.doi.org/10.26787/nydha-2713-203x-2020-1-10-11-12-66-69.

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The article presents the results of our own research on the features of the clinical course of chronic hepatitis C (HCV) in HIV-infected patients at various stages, the disease of which proceeded against the background of drug addiction. CGC was clinically characterized by the absence of vivid symptoms of hepatitis, masked not only by the symptom complex of drug addiction, but also by the concomitant pathology that determines the symptoms of HIV infection in the stage of secondary diseases. Chronic hepatitis C against the background of drug addiction is characterized by early reactivation with
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Михайлов, А. О., С. А. Сокотун, А. И. Дубиков, et al. "A clinical case of a sepsis-like course of coronavirus infection on the background of primary metabolic gout." Лечащий врач, no. 11(26) (November 29, 2023). http://dx.doi.org/10.51793/os.2023.26.11.010.

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Введение. Нередко считают, что подагра – это нераспространенное заболевание и поэтому она не представляет большого интереса для врачей широкого профиля. Однако заболеваемость подагрой в мире неуклонно растет, что объясняется увеличением в популяции лиц с гиперурикемией. Аллергические реакции, несоблюдение режима лечения, лекарственные взаимодействия, а иногда и неэффективность гипоурикемической терапии приводят к тяжелому течению заболевания. Подагра нередко протекает в сочетании с такими патологиями, как ожирение, сахарный диабет, артериальная гипертензия, и другими. В настоящее время предста
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Holubovska, Olga, and Volodymyr Vysotskyi. "Justification of the integrated approach to management of hiv-infected patients with comorbid pathology of the digestive system." Psychosomatic Medicine and General Practice 5, no. 2 (2020). http://dx.doi.org/10.26766/pmgp.v5i2.259.

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Introduction. Among the main strategic and operational goals of the State Strategy for Combating HIV / AIDS, Tuberculosis and Viral Hepatitis by 2030 in Ukraine is to ensure comprehensive access to HIV treatment, increase the effectiveness of monitoring and support of treatment of both opportunistic infections and other somatic conditions in HIV-infected patients. The key role of family physicians in the detection and treatment of many chronic gastrointestinal complications in HIV-infected patients is recognized.&#x0D; Purpose of the study. To increase the efficiency of early diagnosis and tac
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Holubovska, Olga, and Volodymyr Vysotskyi. "Justification of the integrated approach to management of hiv-infected patients with comorbid pathology of the digestive system." Psychosomatic Medicine and General Practice 5, no. 2 (2020). http://dx.doi.org/10.26766/pmgp.v5i2.259.

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Introduction. Among the main strategic and operational goals of the State Strategy for Combating HIV / AIDS, Tuberculosis and Viral Hepatitis by 2030 in Ukraine is to ensure comprehensive access to HIV treatment, increase the effectiveness of monitoring and support of treatment of both opportunistic infections and other somatic conditions in HIV-infected patients. The key role of family physicians in the detection and treatment of many chronic gastrointestinal complications in HIV-infected patients is recognized.&#x0D; Purpose of the study. To increase the efficiency of early diagnosis and tac
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