Gotowa bibliografia na temat „Auto lymphocyte therapy”

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Artykuły w czasopismach na temat "Auto lymphocyte therapy"

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Sackstein, Robert, Jane L. Messina, and Gerald J. Elfenbein. "In vitro adherence of lymphocytes to dermal endothelium under shear stress: implications in pathobiology and steroid therapy of acute cutaneous GVHD." Blood 101, no. 2 (2003): 771–78. http://dx.doi.org/10.1182/blood-2002-05-1452.

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The extravasation of leukocytes at sites of inflammation critically depends on initial shear-resistant adhesive interactions between leukocytes in blood flow and target tissue endothelium. Dermal lymphocytic infiltrates are a hallmark feature of acute cutaneous graft-versus-host disease (acGVHD) following allogeneic hematopoietic stem cell (allo-HSC) transplantation. These infiltrates occur commonly during periods of profound lymphopenia, suggesting that the dermal endothelial adhesive mechanism(s) promoting lymphocyte emigration in acGVHD are highly efficient. To examine this issue, we perfor
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Moturi, Krishna, Harsh Sharma, and Neda Hashemi-Sadraei. "Nephrotoxicity in the Age of Immune Checkpoint Inhibitors: Mechanisms, Diagnosis, and Management." International Journal of Molecular Sciences 25, no. 1 (2023): 414. http://dx.doi.org/10.3390/ijms25010414.

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Immune checkpoint inhibitors (ICI) revolutionized cancer therapy by augmenting anti-tumor immunity via cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed death-1/programmed death-ligand 1 (PD-1/PD-L1). However, this breakthrough is accompanied by immune-related adverse effects (irAEs), including renal complications. ICI-related nephritis involves complex mechanisms like auto-reactive T cells, auto-antibodies, reactivation of drug-specific T cells, and cytokine-driven inflammation culminating in AKI. ICI-AKI typically manifests weeks to months into treatment, often with other i
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Esina, E. "An Experience of Intravaginal Auto Lymphocyte Therapy in Treatment of Female Patients with Infertility: A Case Report." British Journal of Medicine and Medical Research 2, no. 2 (2012): 150–56. http://dx.doi.org/10.9734/bjmmr/2012/904.

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Rose, Ashley, Quinto J. Gesiotto, Leidy Isenalumhe, et al. "Lymphocyte Recovery Following Autologous Hematopoietic Stem Cell Transplant in Classical Hodgkin Lymphoma." Blood 138, Supplement 1 (2021): 2913. http://dx.doi.org/10.1182/blood-2021-150542.

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Abstract Introduction: The standard of care for relapsed/refractory (R/R) classical Hodgkin lymphoma (cHL) is salvage therapy followed by autologous hematopoietic stem cell transplant (auto-HCT). Pre-apheresis absolute lymphocyte count (PA-ALC) is an independent prognostic factor for overall survival (OS) after transplant. We aimed to evaluate the effect of absolute lymphocyte count following auto-HCT and hypothesized that a higher post-transplant ALC at day +15 (PT-ALC) correlates with improved OS. Methods: A retrospective review was performed on patients with R/R cHL who underwent auto-HCT a
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Gul, Zartash, Stephan Anderson, Stacey Slone, et al. "Is Rituximab Needed With High Dose Chemotherapy and Autologous Stem Cell Transplant When Patients With Non-Hodgkin’s Lymphoma Have Been Exposed To It?" Blood 122, no. 21 (2013): 5552. http://dx.doi.org/10.1182/blood.v122.21.5552.5552.

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Abstract Introduction The value of Rituximab with High dose chemotherapy and autologous stem cell transplant (auto-HCT) has been evaluated in some retrospective studies. It is noted that the addition Rituximab to auto-HCT results in significant improvement in overall (OS) and disease free survival (DFS). However, it is unclear that the addition of Rituximab with auto-HCT would result in significant benefit in patients who have received prior Rituximab based therapy. Methods We retrospectively evaluated twenty seven consecutive patients who had B cell non-Hodgkin's lymphoma (NHL) and underwent
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Moviglia, G. A., C. Gaeta, G. Varela, et al. "Tumor-associated stroma cell therapy in patients with pancreatic cancer potentiates therapeutic effect of tumor B-cell hybrid (TBH) auto-vaccines." Journal of Clinical Oncology 25, no. 18_suppl (2007): 4569. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.4569.

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4569 Background: Pancreatic Cancer (PC) tumor-associated stroma cells play an important role in PC’s immune surveillance escape. Secretion of Transforming Growth Factor β (TGFβ) and IL10 by PC tumor cells disturb the antigen presenting function of the stroma cells. It may explain the poor results of most immunotherapeutic approaches. Granger et al. reported a successful approach for treating small size pancreatic tumors, namely Mixed Lymphocyte Culture (MLC) cytoimplant. MLC cytoimplants, acting as a Th1 cytokine pump inside the tumor, are thought to revert the tumor-associated stroma cell dys
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Kil'dyushevskiy, A. V., V. A. Molochkov, T. A. Mitina, Ya G. Moysyuk, and A. V. Molochkov. "Extracorporeal photopheresis as a non-specific immune therapy of autoimmune diseases and skin T-cell lymphoma (a review of the literature and own studies)." Almanac of Clinical Medicine 47, no. 5 (2019): 419–34. http://dx.doi.org/10.18786/2072-0505-2019-47-061.

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Aim: To present well-known and disputable mechanisms of the effects of extracorporeal photopheresis (ECP) in heterogeneous clinical conditions, as well as to demonstrate its advantages over conventional hormonal, immunosuppressive and cytostatic treatments, with a recommendation to widely implement it into practical management of autoimmune disease and cutaneous T-cell lymphomas (CTCLs).Key points: Despite convincing evidence of the ECP efficacy in the treatment of T-cell mediated disorders, a unifying concept of its mechanism has not been established so far. In this review, we attempted to de
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Stover, D. G., V. K. Reddy, Y. Shyr, B. N. Savani, and N. Reddy. "Long-term impact of prior rituximab therapy and early lymphocyte recovery on auto-SCT outcome for diffuse large B-cell lymphoma." Bone Marrow Transplantation 47, no. 1 (2011): 82–87. http://dx.doi.org/10.1038/bmt.2011.29.

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Milovanovic, Ivan, Nevena Popovac, Aleksandar Sretenovic, Nina Ristic, and Radmila Jankovic. "Autoimmune intestinal leiomyositis as a rare cause of chronic intestinal pseudo-obstruction in children: Case report with literature review." Srpski arhiv za celokupno lekarstvo, no. 00 (2025): 8. https://doi.org/10.2298/sarh241210008m.

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Introduction. Chronic intestinal pseudo-obstruction represents a group of rare disorders characterized by impaired gastrointestinal motility in the absence of mechanical bowel obstruction. These disorders can be primary or secondary, with autoimmune intestinal leiomyositis falling into the latter category. This condition is observed in adolescence and adulthood but is very rarely seen in children, especially in infancy. Case outline. A nine-month-old male infant was hospitalized due to persistent vomiting, abdominal bloating, and distension. After diagnostic evaluations and failure of conserva
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Zimmerman, Daniel, Katalin Mikecz, Julia Kurko, Tibor Glant, Harold Steiner, and Roy Carambula. "LEAPS peptide vaccination alters T cell phenotype and suppresses joint inflammation in a murine model of rheumatoid arthitis (P5223)." Journal of Immunology 190, no. 1_Supplement (2013): 67.6. http://dx.doi.org/10.4049/jimmunol.190.supp.67.6.

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Abstract Introduction. A major therapeutic goal in autoimmune inflammatory diseases such as rheumatoid arthritis (RA) is to suppress responses against (auto)antigens present in the target organs. Antigen-specific therapies such as the Ligand Epitope Antigen Presentation System (LEAPS) technology offer such a possibility. Materials and Methods. We evaluated LEAPS therapy in the cartilage proteoglycan (PG) induced arthritis (PGIA) model of RA. After the onset of PGIA, mice were divided in 3 groups, each with a similar mean arthritis index (AI). One group was vaccinated with adjuvant only, and th
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Rozprawy doktorskie na temat "Auto lymphocyte therapy"

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Gherardi, Léa. "BTLA, une nouvelle cible thérapeutique pour le traitement du lupus ?" Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAJ106.

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Le lupus est une maladie auto-immune caractérisée par la présence d’auto-anticorps. Ces derniers sont produits par des lymphocytes B (LB) différenciés en plasmocytes, et ayant bénéficié de l’aide des lymphocytes T (LT). Le dialogue entre LT et LB est régulé par des récepteurs inhibiteurs comme B and T Lymphocyte Attenuator (BTLA), dont l’expression et la fonction sont altérées chez les patients lupiques. Mon projet de thèse visait à évaluer le potentiel thérapeutique du ciblage de BTLA par un anticorps (Ac) agoniste dans un modèle murin de lupus. Nous avons montré chez les souris NZB/W, partag
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Maho, Maud. "Evaluation des effets des traitements par Rituximab versus corticothérapie seule sur la réponse auto-réactive des patients atteints de pemphigus. First-line Rituximab combined with short-term Prednisone versus Prednisone alone for the treatment of Pemphigus (RITUX 3) : a prospective, multicentre, parallel-group, open-label randomised trial Risk factors for short-term relapse in patients with pemphigus treated by Rituximab as first-line therapy Rituximab and corticosteroid effect on Desmoglein specific B cells and T follicular helper cells in patients with Pemphigus Modifications or the transcriptomic profile of autoreactive B cells from pemphigus patients after treatment with Rituximab or standard corticosteroid regimen Long-term increase of Kcnn4 potassium channel surface expression on B cells in pemphigus patients after Rituximab treatment Rituximab is an effective treatment in patients with Pemphigus Vulgaris and demonstrates a steroid-sparing effect Modifications of the BAFF/BAFF-Receptor axis in patients with pemphigus treated with rituximab versus standard corticosteroids regimen. CD11C+ B cells are mainly memory cells prone to differentiate into antibody-secreting cells." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR132.

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Le pemphigus est une maladie auto-immune spécifique de la peau et des muqueuses provoqué par des auto-anticorps (Ac) spécifiques des desmogléines (Dsg) 1 ou 3. Ces Ac pathogéniques inhibent l'adhésion cellulaire des kératinocytes. Le pemphigus se déclenche par la conjonction d’événements rares impliquant l’émergence puis la coopération de lymphocytes B (LB) et de lymphocytes LT auto-réactifs dans un contexte génétique et environnemental particulier. Jusqu’à présent, la première ligne de traitement du pemphigus était constituée de fortes doses de corticoïdes, qui sont de puissants immunosupress
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Zacharovová, Klára. "Diagnostický příspěvek k hodnocení intervenčních modelů léčby diabetu mellitu 1. typu." Doctoral thesis, 2012. http://www.nusl.cz/ntk/nusl-305984.

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During treatment of diabetes mellitus by immunointervention or transplantation, it is necessary to monitor the markers of immune destruction or rejection of surviving insulin producing cells. An aim of this thesis is to improve the possibilities of following autoimmunity and to detect the survival of transplanted pancreatic islet in vivo. Partial aims included vitality testing of isolated islets for transplantation by measurement of respiration activity, observing the process of in vitro labeling of isolated islets with superparamagnetic iron oxide (SPIO) contrast agent for subsequent magnetic
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Części książek na temat "Auto lymphocyte therapy"

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Hall, Angela, Chris Scott, and Matthew Buckland. "Autoimmune skin disease." In Clinical Immunology. Oxford University Press, 2016. http://dx.doi.org/10.1093/hesc/9780199657650.003.0008.

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This chapter looks at autoimmune skin diseases such as pemphigoid and pemphigus. It notes how auto-antibodies are directed against protein at the dermal-epidermal junction in the pemphigoid, while pemphigus has auto-antibodies directed against cell junctions in the epidermis. The chapter indicates that specific auto-antibodies are associated with disruption of the skin structure leading to blistering. Biopsies or serums can demonstrate the presence of auto-antibodies as well. The chapter shows how treatment can include steroid, topic, systemic, steroid-sparing systemic immune suppression, high
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