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Gotowe bibliografie tematyczne / Bio-inspired Small Molecules

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Artykuły w czasopismach

Gotowa bibliografia na temat „Bio-inspired Small Molecules”

Autor: Grafiati

Data publikacji: 7 września 2023

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Artykuły w czasopismach na temat "Bio-inspired Small Molecules"

1

Roldan, A., N. Hollingsworth, A. Roffey, et al. "Bio-inspired CO2conversion by iron sulfide catalysts under sustainable conditions." Chemical Communications 51, no. 35 (2015): 7501–4. http://dx.doi.org/10.1039/c5cc02078f.

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2

Mougel, Victor. "Bio-inspired Molecules and Materials: CO2 Reduction as a Case Study." CHIMIA International Journal for Chemistry 74, no. 9 (2020): 710–15. http://dx.doi.org/10.2533/chimia.2020.710.

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This account reviews our recent research activities in the field of CO2 reduction. We discuss here the potential of the bio-inspired approach for the design of electrocatalytic systems for small molecule transformation. Exploiting the billion years of evolution of natural systems, we illustrate the potential of bio-inspired strategies across multiple scales to design catalytic systems. We demonstrate in particular how the shape of biological systems as well as enzymatic active sites and their environment can constitute effective sources of inspiration for the design of electrocatalysts with improved performances.

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3

Almeida, Joana R., Andreia Palmeira, Alexandre Campos, et al. "Structure-Antifouling Activity Relationship and Molecular Targets of Bio-Inspired(thio)xanthones." Biomolecules 10, no. 8 (2020): 1126. http://dx.doi.org/10.3390/biom10081126.

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The development of alternative ecological and effective antifouling technologies is still challenging. Synthesis of nature-inspired compounds has been exploited, given the potential to assure commercial supplies of potential ecofriendly antifouling agents. In this direction, the antifouling activity of a series of nineteen synthetic small molecules, with chemical similarities with natural products, were exploited in this work. Six (4, 5, 7, 10, 15 and 17) of the tested xanthones showed in vivo activity toward the settlement of Mytilus galloprovincialis larvae (EC50: 3.53–28.60 µM) and low toxicity to this macrofouling species (LC50 > 500 µM and LC50/EC50: 17.42–141.64), and two of them (7 and 10) showed no general marine ecotoxicity (<10% of Artemia salina mortality) after 48 h of exposure. Regarding the mechanism of action in mussel larvae, the best performance compounds 4 and 5 might be acting by the inhibition of acetylcholinesterase activity (in vitro and in silico studies), while 7 and 10 showed specific targets (proteomic studies) directly related with the mussel adhesive structure (byssal threads), given by the alterations in the expression of Mytilus collagen proteins (PreCols) and proximal thread proteins (TMPs). A quantitative structure-activity relationship (QSAR) model was built with predictive capacity to enable speeding the design of new potential active compounds.

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4

Rondelli, Cola, Koutsioubas, et al. "Mucin Thin Layers: A Model for Mucus-Covered Tissues." International Journal of Molecular Sciences 20, no. 15 (2019): 3712. http://dx.doi.org/10.3390/ijms20153712.

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The fate of macromolecules of biological or pharmacological interest that enter the mucus barrier is a current field of investigation. Studies of the interaction between the main constituent of mucus, mucins, and molecules involved in topical transmucoidal drug or gene delivery is a prerequisite for nanomedicine design. We studied the interaction of mucin with the bio-inspired arginine-derived amphoteric polymer d,l-ARGO7 by applying complementary techniques. Small angle X-ray scattering in bulk unveiled the formation of hundreds of nanometer-sized clusters, phase separated from the mucin mesh. Quartz microbalance with dissipation and neutron reflectometry measurements on thin mucin layers deposited on silica supports highlighted the occurrence of polymer interaction with mucin on the molecular scale. Rinsing procedures on both experimental set ups showed that interaction induces alteration of the deposited hydrogel. We succeeded in building up a new significant model for epithelial tissues covered by mucus, obtaining the deposition of a mucin layer 20 Å thick on the top of a glycolipid enriched phospholipid single membrane, suitable to be investigated by neutron reflectometry. The model is applicable to unveil the cross structural details of mucus-covered epithelia in interaction with macromolecules within the Å discreteness.

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5

Romera, David, Pierre Couleaud, Sara H. Mejias, Antonio Aires, and Aitziber L. Cortajarena. "Biomolecular templating of functional hybrid nanostructures using repeat protein scaffolds." Biochemical Society Transactions 43, no. 5 (2015): 825–31. http://dx.doi.org/10.1042/bst20150077.

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The precise synthesis of materials and devices with tailored complex structures and properties is a requisite for the development of the next generation of products based on nanotechnology. Nowadays, the technology for the generation of this type of devices lacks the precision to determine their properties and is accomplished mostly by ‘trial and error’ experimental approaches. The use of bottom-up approaches that rely on highly specific biomolecular interactions of small and simple components is an attractive approach for the templating of nanoscale elements. In nature, protein assemblies define complex structures and functions. Engineering novel bio-inspired assemblies by exploiting the same rules and interactions that encode the natural diversity is an emerging field that opens the door to create nanostructures with numerous potential applications in synthetic biology and nanotechnology. Self-assembly of biological molecules into defined functional structures has a tremendous potential in nano-patterning and the design of novel materials and functional devices. Molecular self-assembly is a process by which complex 3D structures with specified functions are constructed from simple molecular building blocks. Here we discuss the basis of biomolecular templating, the great potential of repeat proteins as building blocks for biomolecular templating and nano-patterning. In particular, we focus on the designed consensus tetratricopeptide repeats (CTPRs), the control on the assembly of these proteins into higher order structures and their potential as building blocks in order to generate functional nanostructures and materials.

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6

Mao, Jing-Yu, Li Zhou, Yi Ren, et al. "A bio-inspired electronic synapse using solution processable organic small molecule." Journal of Materials Chemistry C 7, no. 6 (2019): 1491–501. http://dx.doi.org/10.1039/c8tc05489d.

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A trap-mediated solution-processed small molecule based artificial synaptic device is presented. This work reveals great potential for a small molecule based artificial synapse to serve in neuromorphic computing.

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7

Reed, Douglas A., Dianne J. Xiao, Henry Z. H. Jiang, Khetpakorn Chakarawet, Julia Oktawiec, and Jeffrey R. Long. "Biomimetic O2 adsorption in an iron metal–organic framework for air separation." Chemical Science 11, no. 6 (2020): 1698–702. http://dx.doi.org/10.1039/c9sc06047b.

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8

Ghosh, Ashta C., Carole Duboc, and Marcello Gennari. "Synergy between metals for small molecule activation: Enzymes and bio-inspired complexes." Coordination Chemistry Reviews 428 (February 2021): 213606. http://dx.doi.org/10.1016/j.ccr.2020.213606.

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9

Wang, Wei, Jindong Liu, Guangming Xie, Li Wen, and Jianwei Zhang. "A bio-inspired electrocommunication system for small underwater robots." Bioinspiration & Biomimetics 12, no. 3 (2017): 036002. http://dx.doi.org/10.1088/1748-3190/aa61c3.

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10

Li, Yin‐Xiang, Xue‐Mei Dong, Meng‐Na Yu, et al. "A Bio‐Inspired Molecular Design Strategy toward 2D Organic Semiconductor Crystals with Superior Integrated Optoelectronic Properties." Small 17, no. 34 (2021): 2102060. http://dx.doi.org/10.1002/smll.202102060.

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