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Gotowe bibliografie tematyczne / Bioavailability of W

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Gotowa bibliografia na temat „Bioavailability of W”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Bioavailability of W"

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Karmańska, Aleksandra, Natalia Rękawiecka, and Bolesław Karwowski. "Coenzyme Q10- metabolism, supplementation, bioavailability." Farmacja Polska 80, no. 9 (2025): 645–56. https://doi.org/10.32383/farmpol/200800.

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Przedmiot badań Koenzym Q10 (CoQ10) 2,3-dimetoksy-5-metylo-6-dekaprenylobenzochinon, nazywany również ubichinonem lub ubidekarenonem odgrywa kluczową rolę w mitochondrialnej fosforylacji oksydacyjnej. W wysokich stężeniach występuje w tkankach wymagających zwiększonej ilości energii: serce, nerki, mięśnie. Efektywność biosyntezy koenzymu Q10 ulega obniżeniu u osób starszych stąd korzystny wpływ może mieć wprowadzenie jego suplementacji. Cel pracy W pracy omówiono zagadnienia dotyczące: • znaczenia koenzymu Q10 w organizmie człowieka jego udział w procesach fosforylacji oksydacyjnej, ferroptozi

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Liu, Chunxia, Li Lv, Wei Guo, et al. "Self-Nanoemulsifying Drug Delivery System of Tetrandrine for Improved Bioavailability: Physicochemical Characterization and Pharmacokinetic Study." BioMed Research International 2018 (September 27, 2018): 1–10. http://dx.doi.org/10.1155/2018/6763057.

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The main purpose of this study was to investigate the potential of self-nanoemulsified drug delivery system (SNEDDS) to improve the oral bioavailability of tetrandrine (Tet). SNEDDS was developed by using rational blends of excipients with good solubilizing ability for Tet which was selected based on solubility studies. Further ternary phase diagram was constructed to determine the self-emulsifying region. The optimal formulation with the best self-nanoemulsified and solubilization ability consisted of 40% (w/w) oleic acid as oil, 15% (w/w) SPC and 30% (w/w) Cremophor RH-40 as surfactant, and

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Singh, Sanjay Kumar, Parameswara Rao Vuddanda, Sanjay Singh, and Anand Kumar Srivastava. "A Comparison between Use of Spray and Freeze Drying Techniques for Preparation of Solid Self-Microemulsifying Formulation of Valsartan andIn VitroandIn VivoEvaluation." BioMed Research International 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/909045.

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The objective of the present study was to develop self micro emulsifying formulation (SMEF) of valsartan to improve its oral bioavailability. The formulations were screened on the basis of solubility, stability, emulsification efficiency, particle size and zeta potential. The optimized liquid SMEF contains valsartan (20% w/w), Capmul MCM C8 (16% w/w), Tween 80 (42.66% w/w) and PEG 400 (21.33% w/w) as drug, oil, surfactant and co-surfactant, respectively. Further, Liquid SMEF was adsorbed on Aerosol 200 by spray and freeze drying methods in the ratio of 2 : 1 and transformed into free flowing p

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Kushwaha, Anjali. "Cashew Nut Starch as Natural Excipient for Improved Bioavailability of Drugs." International Journal of Pharmaceutical Sciences and Nanotechnology 12, no. 4 (2019): 4616–22. http://dx.doi.org/10.37285/ijpsn.2019.12.4.8.

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The bioavailability of drug is affected by various excipients present in the formulation. In case of tablets, the role of binders is very important for release of drug and bioavailability. In the present study, starch was extracted from the cashew nuts and used as binding agentat a concentration of 2% w/v, 4% w/v, 6% w/v and 8% w/v. The tablets were formulated by using famotidine drug and they were further evaluated for various parameters like weight variation, hardness, friability, disintegration time, in vitro and in vivo drug release. The results show that all parameters were found within t

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Zhou, Huafeng, Guoqing Liu, Jing Zhang, et al. "Novel Lipid-Free Nanoformulation for Improving Oral Bioavailability of Coenzyme Q10." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/793879.

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To improve the bioavailability of orally administered lipophilic coenzyme Q10 (CoQ10), we formulated a novel lipid-free nano-CoQ10 system stabilized by various surfactants. Nano-CoQ10s, composed of 2.5% (w/w) CoQ10, 1.67% (w/w) surfactant, and 41.67% (w/w) glycerol, were prepared by hot high-pressure homogenization. The resulting formulations were characterized by particle size, zeta potential, differential scanning calorimetry, and cryogenic transmission electron microscopy. We found that the mean particle size of all nano-CoQ10s ranged from66.3±1.5 nm to92.7±1.5 nm and the zeta potential ran

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Jang, Ji-Hun, Seung-Hyun Jeong, and Yong-Bok Lee. "Enhanced Lymphatic Delivery of Methotrexate Using W/O/W Nanoemulsion: In Vitro Characterization and Pharmacokinetic Study." Pharmaceutics 12, no. 10 (2020): 978. http://dx.doi.org/10.3390/pharmaceutics12100978.

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Methotrexate, which is widely used in the treatment of cancer and immune-related diseases, has limitations in use because of its low bioavailability, short half-life, and tissue toxicity. Thus, in this study, a nano-sized water-in-oil-in-water (W/O/W) double emulsion containing methotrexate was prepared to enhance its lymphatic delivery and bioavailability. Based on the results from solubility testing and a pseudo-ternary diagram study, olive oil as the oil, Labrasol as a surfactant, and ethanol as a co-surfactant, were selected as the optimal components for the nanoemulsion. The prepared nano

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Wang, Chih-Yuan, Ching-Chi Yen, Mei-Chich Hsu, and Yu-Tse Wu. "Self-Nanoemulsifying Drug Delivery Systems for Enhancing Solubility, Permeability, and Bioavailability of Sesamin." Molecules 25, no. 14 (2020): 3119. http://dx.doi.org/10.3390/molecules25143119.

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Sesamin (SSM) is a water-insoluble compound that is easily eliminated by liver metabolism. To improve the solubility and bioavailability of SSM, this study developed and characterized a self-nanoemulsifying drug delivery system (SNEDDS) for the oral delivery of SSM and conducted pharmacokinetic assessments. Oil and surfactant materials suitable for SNEDDS preparation were selected on the basis of their saturation solubility at 37 ± 0.5 °C. The mixing ratios of excipients were determined on the basis of their dispersibility, transmittance (%), droplet sizes, and polydispersity index. An SNEDDS

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Kushwaha, Anjali, and Pratap Manjul Singh. "Role of naturally isolated pear starch on the bioavailability of famotidine." Journal of Drug Delivery and Therapeutics 9, no. 3 (2019): 430–35. http://dx.doi.org/10.22270/jddt.v9i3.2704.

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Purpose- The bioavailability of any drug in the formulation is affected by various excipients presents in it. In case of tablets the role of binders is very important for dissolution of dosage form as well as bioavailability of drug. Thus in following study an attempt is made to improve the dissolution of drug by using pear starch as binding agents. The starch was extracted from the Pear fruits and used as a binder in different concentrations, in famotidine tablets and then evaluate them. Methods-The tablets were formulated by wet granulation method by using 2% w/v, 4% w/v, 6% w/v and 8% w/v o

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Madonna, Sandra, Agus Jatnika Effendi, Edwan Kardena, and Syarif Hidayat. "Bioavailability enhancement of petroleum-contaminated soil by electrokinetic remediation." E3S Web of Conferences 485 (2024): 02007. http://dx.doi.org/10.1051/e3sconf/202448502007.

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The Electro kinetic Remediation Technology (EKR) is recognized as the most potential remediation technology for soils with low permeability, like clay soil characteristics. Electrokinetic treatment could increase the bioavailability of contaminants in bioremediation petroleum-contaminated soil. The study, “Bioavailability enhancement of petroleum contaminated soil by electrokinetic remediation,” is experimental research in a laboratory to improve the bioavailability of petroleum hydrocarbons on clay during bioremediation with initial treatment using electrokinetic remediation techniques, findi

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Yang, Chen, Yixiang Wang, Yike Xie, et al. "Oat protein-shellac nanoparticles as a delivery vehicle for resveratrol to improve bioavailability in vitro and in vivo." Nanomedicine 14, no. 21 (2019): 2853–71. http://dx.doi.org/10.2217/nnm-2019-0244.

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Aim: Oat protein-shellac nanoparticles (NPs) were developed as a delivery system for resveratrol to improve bioavailability. Materials & methods: The NPs were prepared from w/w emulsion followed by cold-gelation. In vitro release and cell uptake mechanism of NPs were estimated by HPLC and confocal laser scanning microscopy. In vivo bioavailability and hepatoprotective activity of encapsulated resveratrol were studied using rat models. Results & conclusion: NPs (90–300 nm) protected resveratrol in gastric fluid, while allowing controlled release into small intestine in vitro. The optimi

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Rozprawy doktorskie na temat "Bioavailability of W"

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Garcia-Fernandez, Jenifer [Verfasser], Michael W. [Gutachter] Linscheid, Maria [Gutachter] Montes-Bayón, and Ulrich [Gutachter] Panne. "Bioavailability studies of Iron Nanoparticles in Biological Samples using Mass Spectrometric Techniques / Jenifer Garcia-Fernandez ; Gutachter: Michael W. Linscheid, Maria Montes-Bayón, Ulrich Panne." Berlin : Humboldt-Universität zu Berlin, 2018. http://d-nb.info/1185174885/34.

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Książki na temat "Bioavailability of W"

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Brzozowska, Anna. Biodostępność żelaza, cynku i miedzi w zależności od ilości i wzajemnych proporcji tych pierwiastków w diecie. Wydawn. SGGW, 1991.

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Części książek na temat "Bioavailability of W"

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Takeda, S., H. Obata, A. Okubo, M. Sato, and Y. Kondo. "Bioavailability and Biogeochemical Processes of Trace Metals in the Surface Ocean." In Western Pacific Air-Sea Interaction Study. TERRAPUB, 2014. http://dx.doi.org/10.5047/w-pass.a03.001.

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T. Galatage, Sunil, Rahul Trivedi, Durgacharan A. Bhagwat, et al. "Self-nano Emulsifying Formulations: An Encouraging Approach for Bioavailability Enhancement and Future Perspective." In Dosage Forms [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108703.

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Currently lipid-based formulations are playing a vital and promising role in improving the oral bioavailability of poorly water-soluble drugs. Lipid based formulations mainly consist of a drug dissolved in lipids such as triglycerides, glycerides, oils and surface active agent. Self nanoemulsifying formulations (SNEF) are isotropic mixtures of lipids/oils, surfactants and co-surfactants. On mild agitation followed by dilution in aqueous media, such as GI fluids, SNEF can form fine oil-in-water (o/w) nanoemulsions. Present chapter summarizes different types of lipid formulations with special em

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Kesavan, Karthikeyan, Parasuraman Mohan, Sunil K. Jain, Olivia Parra-Marín, and Selvasankar Murugesan. "Nanoemulsion: A Potential Carrier for Topical Drug Delivery." In Nanoparticles and Nanocarriers-Based Pharmaceutical Formulations. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049787122010011.

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Nanoemulsions (NEs) are stable nanocarrier systems consisting mainly of oil and water, which are stabilized by surfactant with cosurfactant. Due to their typical size, nano-emulsions are transparent or translucent, and minute droplet size makes them stable against sedimentation or creaming. The nanoemulsion system may be in the form of oil-in-water (O/W) or water-in-oil (W/O). The recent literature revealed that NEs as a colloidal carrier system has been confirmed to be a valuable strategy to improve the bioavailability of topically applied drugs. NE has been proposed as a viable alternative t

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Streszczenia konferencji na temat "Bioavailability of W"

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Emanuele, R. M., and J. Fareed. "THE EFFECT OF MOLECULAR WEIGHT ON THE RELATIVE BIOAVAILABILITY OF HEPARIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644179.

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Three fractions of different molecular weight (M. W.) were obtained from gel-filtration of porcine mucosal heparin. These fractions along with unfractionated and a low M. W. heparin (CY 216) were compared for relative bioavailability in primates (Macaca mulatta: n = 5). The M. W.'s of all fractions were determined using high performance liquid chromatography - gel permeation and characterizied in terms of mean M. W., peak M. W. and M. W. distribution. Area under the plasma concentration time curve (AUC) was calculated by the trapezoidal method after intravenous and subcutaneous administration

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Neves, Marcos A., Isao Kobayashi, and Mitsutoshi Nakajima. "Scaling-Up Microchannel Emulsification Foreseeing Novel Bioactives Delivery Systems." In ASME 2013 11th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icnmm2013-73116.

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In the recent years, emulsification technologies that generate droplets individually have attracted a great deal attention in various fields, e.g., for chemicals, cosmetics, foods, and pharmaceuticals. Such drop-by-drop emulsification technologies include membrane emulsification using microporous membranes and microchannel (MC) emulsification, among others. The authors developed MC emulsification chips, consisting of parallel microgrooves or compactly arranged straight through-holes. Using this MC emulsification technique, the authors have evaluated the formulation a two-phase system consistin

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Raporty organizacyjne na temat "Bioavailability of W"

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Tengamnuay, Parkpoom. Efficacy and mechanistic studies of chitosan as nasal absorption enhancer of peptide drugs : research report. Chulalongkorn University, 1999. https://doi.org/10.58837/chula.res.1999.27.

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Objective. To evaluation the in vivo efficacy of chitosan as nasal absorption enhancers of peptides in rats and compare the results with that of hydroxypropyl- and dimethyl-Beta-cyclodextrins (HPBetaCD and DMBetaCD). Methods. Two types of chitosan. i.e., the free base (CSJ) and the glutamate salt form (CSG) were evaluated for their nasal absorption enhancing effect on salmon calcitonin (sCT) using an in vibo rat absorption technique. Solutions containing sCT and chitosan (0 to 1.25 % w/v) in isotonic phosphate buffers (pH 3.0 to 6.0) were nasally administered at the dose of 10 IU/kg. The plasm

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