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Artykuły w czasopismach na temat "Bone Diseases, Metabolic – physiopathology"

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Izzo, Marcello, Albino Carrizzo, Carmine Izzo, et al. "Vitamin D: Not Just Bone Metabolism but a Key Player in Cardiovascular Diseases." Life 11, no. 5 (2021): 452. http://dx.doi.org/10.3390/life11050452.

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Vitamin D is the first item of drug expenditure for the treatment of osteoporosis. Its deficiency is a condition that affects not only older individuals but also young people. Recently, the scientific community has focused its attention on the possible role of vitamin D in the development of several chronic diseases such as cardiovascular and metabolic diseases. This review aims to highlight the possible role of vitamin D in cardiovascular and metabolic diseases. In particular, here we examine (1) the role of vitamin D in diabetes mellitus, metabolic syndrome, and obesity, and its influence on
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Iaconis, Antonella, Francesco Molinari, Roberta Fusco, and Rosanna Di Paola. "Mitochondria as a Disease-Relevant Organelle in Rheumatoid Arthritis: A Key Breakout in Fight Against the Disease." Biomedicines 13, no. 7 (2025): 1708. https://doi.org/10.3390/biomedicines13071708.

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Rheumatoid arthritis (RA) is one of the most representative autoimmune diseases. The peculiarity of this disease is synovial inflammation, which results in joint destruction and often disability. Although there are still several pathogenetic mechanisms to be clarified, lately, most studies have highlighted the involvement of mitochondria in the onset and progression of the disease. Mitochondrial functions are connected to many metabolic processes and the delivery of proinflammatory mediators. Mitochondria play a crucial role in the physiopathology of RA, contributing to chronic inflammation, c
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Biver, Emmanuel, Pierre Hardouin, and Joseph Caverzasio. "The “bone morphogenic proteins” pathways in bone and joint diseases: Translational perspectives from physiopathology to therapeutic targets." Cytokine & Growth Factor Reviews 24, no. 1 (2013): 69–81. http://dx.doi.org/10.1016/j.cytogfr.2012.06.003.

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Smiljić, Lj, M. Radunović, M. Muratović, and T. Smilić. "ADIPOKINES AS FOR RUNNERS OF INFLAMMATORY CITOKINE SUPERFAMILY AND ITS INVOLVEMENT IN INFLAMMATORY AND IMMUNE DISEASES." Praxis medica 37, no. 2 (2009): 135–41. http://dx.doi.org/10.70949/pramed200902311s.

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<p>Leptin was discovered in 1994, finding, that marked the beginning of a new understanding about white adipose tissue. Up to end of 20th century this tissue was viewed as an inert tissue, devoted to body protection from heat loss and to passively store energy. This static vision, changed with identification of the product of the gene obese (ob) wich accentuated the role of adipose tissue in the physiopathology of obesity-linked diseases, and led to the discovery of various adipokines, many of a pro-inflammatory nature. With emerged knowledge of (WAT)-derived adipokines, it is ob
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Grill, Vivian, and T. John Martin. "Metabolic bone diseases." Medical Journal of Australia 163, no. 1 (1995): 38–41. http://dx.doi.org/10.5694/j.1326-5377.1995.tb126087.x.

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SEINO, YOSHIKI. "Metabolic bone diseases." Pediatrics International 39, no. 4 (1997): 478. http://dx.doi.org/10.1111/j.1442-200x.1997.tb03623.x.

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Horvai, Andrew E., and Brendan F. Boyce. "Metabolic bone diseases." Seminars in Diagnostic Pathology 28, no. 1 (2011): 13–25. http://dx.doi.org/10.1053/j.semdp.2011.02.004.

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Dubois-Deruy, Emilie, Yara El Masri, Annie Turkieh, Philippe Amouyel, Florence Pinet, and Jean-Sébastien Annicotte. "Cardiac Acetylation in Metabolic Diseases." Biomedicines 10, no. 8 (2022): 1834. http://dx.doi.org/10.3390/biomedicines10081834.

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Lysine acetylation is a highly conserved mechanism that affects several biological processes such as cell growth, metabolism, enzymatic activity, subcellular localization of proteins, gene transcription or chromatin structure. This post-translational modification, mainly regulated by lysine acetyltransferase (KAT) and lysine deacetylase (KDAC) enzymes, can occur on histone or non-histone proteins. Several studies have demonstrated that dysregulated acetylation is involved in cardiac dysfunction, associated with metabolic disorder or heart failure. Since the prevalence of obesity, type 2 diabet
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Dumond Bourie, Aurore, Jean-Baptiste Potier, Michel Pinget, and Karim Bouzakri. "Myokines: Crosstalk and Consequences on Liver Physiopathology." Nutrients 15, no. 7 (2023): 1729. http://dx.doi.org/10.3390/nu15071729.

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Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease mainly characterized by the hepatic accumulation of lipid inducing a deregulation of β-oxidation. Its advanced form is non-alcoholic steatohepatitis (NASH), which, in addition to lipid accumulation, induces hepatocellular damage, oxidative stress and fibrosis that can progress to cirrhosis and to its final stage: hepatocellular carcinoma (HCC). To date, no specific therapeutic treatment exists. The implications of organ crosstalk have been highlighted in many metabolic disorders, such as diabetes, metabolic-associated liver d
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Sánchez-Oliver, Antonio Jesús. "Obesity Phisiopathology: Current Perspectives." Journal of Nutritional Biology 4, no. 1 (2017): 21. http://dx.doi.org/10.18314/jnb.v4i1.160.

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Obesity is a global health problem, being considered one of the most serious and prevalent non-communicable diseases of the 21st century. It is currently understood as a multifactorial chronic condition associated with potentially serious complications whose treatment requires a multidisciplinary approach, given its huge clinical impact and associated health-carecost. Besides, properly tackling obesity requires a founded knowledge of its specific physiopathology is required. Together withthe rise in adiposity, a series of cellular processes happen, which cause several metabolic changes that dr
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Rozprawy doktorskie na temat "Bone Diseases, Metabolic – physiopathology"

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Laketic-Ljubojevic, Ira. "Glutamate signalling in bone cells." Thesis, University of York, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311080.

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Taylor, Amanda Faith. "The role of glutamate in bone formation in vitro." Thesis, University of York, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341824.

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Samnegård, Eva. "Pharmacological and hormonal effects on bone with emphasis on osteoporosis : experimental studies in the rat /." Stockholm : Karolinska Univ. Press, 2001. http://diss.kib.ki.se/2001/91-89428-08-0/.

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Karunaratne, Malintha P. Angelo. "Analysis of alterations in matrix quality at nanoscale in metabolic bone diseases using synchrotron X-ray diffraction." Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8490.

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Bone diseases such as osteoporosis and rickets cause significant reduction in bone quantity and quality, leading to mechanical abnormalities. While the reduction of bone quantity can be assessed using clinical tools like DXA and pQCT, there is little quantitative knowledge of how altered bone quality in diseased bone increases fracture risk. There is a clear need to develop high-resolution diagnostic techniques to close the gap between onset of fracture relevant changes and diagnosis. Here, a functional imaging technique (in situ synchrotron X-ray imaging with micromechanics) was developed to
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Simmons, Natalie Renee. "CHEST X-RAY CLUES TO OSTEOPOROSIS: CRITERIA, CORRELATIONS, AND CONSISTENCY." Yale University, 2009. http://ymtdl.med.yale.edu/theses/available/etd-04162009-161245/.

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The purpose of this study was to determine whether radiologists could accurately assess osteopenia on chest plain films. Two chest radiologists evaluated lateral chest films from 100 patients (80 female and 20 male), ranging in age from 16 to 86 years, for osteopenia and its associated findings. Intra- and interobserver agreement was determined using weighted kappa statistics, and accuracy was assessed by making comparisons to bone mineral density as measured by the non-invasive gold standard of dual-energy x-ray absorptiometry (DXA). Overall, radiologists were good at identifying signs of lat
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Ueno, Melise Jacon Peres [UNESP]. "Efeitos do desuso e da deficiência de estrógeno sobre a microarquitetura óssea e suas propriedades biomecânicas." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/134197.

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Made available in DSpace on 2016-02-05T18:30:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-07-28. Added 1 bitstream(s) on 2016-02-05T18:34:16Z : No. of bitstreams: 1 000857773.pdf: 1062070 bytes, checksum: 71a62107765cf558c1418c16cda5314d (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O objetivo desse estudo foi analisar se há diferenças no efeito do desuso e da deficiência de estrógeno sobre o tecido ósseo trabecular e cortical, e se estes efeitos influenciam na qualidade do tecido ósseo aumentando sua fragilidade. Para este estudo, 30 ratas Wi
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Ueno, Melise Jacon Peres. "Efeitos do desuso e da deficiência de estrógeno sobre a microarquitetura óssea e suas propriedades biomecânicas /." Araçatuba, 2015. http://hdl.handle.net/11449/134197.

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Orientador: Mário Jefferson Quirino Louzada<br>Banca: William Dias Belangero<br>Banca: José Carlos Camargo Filho<br>Resumo: O objetivo desse estudo foi analisar se há diferenças no efeito do desuso e da deficiência de estrógeno sobre o tecido ósseo trabecular e cortical, e se estes efeitos influenciam na qualidade do tecido ósseo aumentando sua fragilidade. Para este estudo, 30 ratas Wistar com 19 semanas de idade foram distribuídas nos grupos: controle (CON), descarregamento dos membros posteriores (HLU) e ovariectomizado (OVX). As análises da densidade óssea in vivo (DXA) dos fêmures e tíbia
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Ahmad, Tashfeen. "Diabetic osteopathy : a study in the rat /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-615-4/.

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Fernandes, Fernanda [UNESP]. "Análise do colo femoral de ratas adultas e senis após tratamento com ocitocina." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/143823.

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Submitted by FERNANDA FERNANDES null (fernanda.fernandes.ata@gmail.com) on 2016-09-08T15:50:56Z No. of bitstreams: 1 DISSERTAÇÃO FERNANDA FERNANDES.pdf: 3056607 bytes, checksum: d763bb262cd01286f3a01d7fb1bcbab4 (MD5)<br>Approved for entry into archive by Juliano Benedito Ferreira (julianoferreira@reitoria.unesp.br) on 2016-09-09T13:14:26Z (GMT) No. of bitstreams: 1 fernandes_f_me_araca.pdf: 3056607 bytes, checksum: d763bb262cd01286f3a01d7fb1bcbab4 (MD5)<br>Made available in DSpace on 2016-09-09T13:14:26Z (GMT). No. of bitstreams: 1 fernandes_f_me_araca.pdf: 3056607 bytes, checksum: d763bb2
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Coêlho, Juliana de Carvalho Apolinário. "Efeito do ultra-som de baixa potência na reparação óssea em ratos sob ausência de carga : análise densitométrica e biomecânica /." Araçatuba : [s.n.], 2008. http://hdl.handle.net/11449/92201.

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Orientador: Mário Jefferson Quirino Louzada<br>Banca: Ivania Garavella<br>Banca: Leda Maria Pescinini Salzedas<br>Resumo: A literatura apresenta que a resposta de reparo ósseo pode ser acentuada pela estimulação física, mecânica ou eletromagnética. Há evidências de que o ultra-som - US - de baixa potência pode acelerar a regeneração óssea. Este trabalho objetivou verificar o efeito do US no defeito ósseo, criado experimentalmente, em tíbias de ratos sob ausência de carga (suspenso pela cauda) por meio de análise densitométrica e biomecânica. Trinta Rattus novergicus albinus, Wistar, adultos, d
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Książki na temat "Bone Diseases, Metabolic – physiopathology"

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1948-, Regling Günter, ed. Wolff's law and connective tissue regulation: Modern interdisciplinary comments on Wolff's law of connective tissue regulation and rational understanding of common clinical problems. W. de Gruyter, 1992.

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Allgrove, Jeremy, and Nick Shaw. Calcium and bone disorders in children and adolescents. 2nd ed. Karger, 2015.

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Jeremy, Allgrove, and Shaw Nick, eds. Calcium and bone disorders in children and adolescents. Karger, 2009.

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Camacho, Pauline M., ed. Metabolic Bone Diseases. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03694-2.

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Paul, Grech, ed. Diagnosis of metabolic bone disease. Chapman and Hall Medical, 1985.

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C, Nordin B. E., Need A. G, and Morris H. A, eds. Metabolic bone and stone disease. 3rd ed. Churchill Livingstone, 1993.

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Salvador, Castells, and Finberg Laurence, eds. Metabolic bone disease in children. M. Dekker, 1990.

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S, Tam Cherk, Heersche Johannes N. M, and Murray Timothy M, eds. Metabolic bone disease: Cellular and tissue mechanisms. CRC Press, 1988.

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C, Stevenson John, ed. New techniques in metabolic bone disease. Wright, 1990.

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W, Weissman Barbara N., ed. Imaging of arthritis and metabolic bone disease. Mosby/Elsevier, 2009.

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Części książek na temat "Bone Diseases, Metabolic – physiopathology"

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Adams, J. E. "Metabolic Bone Disease." In Musculoskeletal Diseases. Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0339-3_14.

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Adler, Claus-Peter. "Metabolic and Storage Diseases." In Bone Diseases. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-04088-1_9.

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Bahk, Yong Whee. "Metabolic Bone Diseases." In Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-662-06294-4_13.

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Thijn, Cornelis J. P. "Metabolic Bone Diseases." In Radiology of the Hand. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-50966-7_6.

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Botton, Miguel, António Robalo Correia, and Manuel Cassiano Neves. "Metabolic Bone Diseases." In General Orthopaedics and Basic Science. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-92193-8_10.

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Bahk, Yong-Whee. "Metabolic Bone Diseases." In Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-04106-2_13.

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Aithal, Hari Prasad, Amar Pal, Prakash Kinjavdekar, and Abhijit M. Pawde. "Metabolic Bone Diseases." In Textbook of Veterinary Orthopaedic Surgery. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-2575-9_9.

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van Daele, P. L. A., and M. C. Zillikens. "Metabolic bone diseases." In Orthopaedics and Traumatology. Bohn Stafleu van Loghum, 2021. http://dx.doi.org/10.1007/978-90-368-2638-9_22.

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Vande Berg, Bruno, Frederic Lecouvet, Paolo Simoni, and Jacques Malghem. "Metabolic Bone Diseases." In Musculoskeletal Diseases 2009–2012. Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-1378-0_16.

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Jasim, Sina, Robert Wermers, and Daniel L. Hurley. "Sclerotic Bone Disorders." In Metabolic Bone Diseases. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03694-2_12.

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Streszczenia konferencji na temat "Bone Diseases, Metabolic – physiopathology"

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Navada, Dinesh K. R., Ganesh S, and Bhargavi K. "A High Precision Deep-CNN Framework for Classification of Metabolic Bone Diseases Among Women." In 2018 3rd International Conference on Communication and Electronics Systems (ICCES). IEEE, 2018. http://dx.doi.org/10.1109/cesys.2018.8724013.

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Cox, L. G. E., C. C. van Donkelaar, B. van Rietbergen, and K. Ito. "Mechanoregulated Bone Remodeling May Explain Bone Structural Changes Observed in Osteoarthritis." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19583.

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Osteoarthritis (OA) affects both the articular cartilage and the subchondral bone. It is a complicated disease, associated with conditions varying from obesity and strenuous exercise to joint malalignment, anterior cruciate ligament (ACL) injury, and even metabolic bone diseases. Patients suffer from chronic joint pain and limitation of motion, and no cure is yet available. For many years, medical therapies have been focused on cartilage, because bone changes were thought not to play a major role in the OA disease process. However, it has been shown that bone changes occur in an early stage of
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Penninger, Charles L., Neal M. Patel, and Andrés Tovar. "A Novel HCA Framework for Simulating the Cellular Mechanisms of Bone Remodeling." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-70613.

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Each year, bone metabolic diseases affect millions of people of all ages, genders, and races. Common diseases such as osteopenia and osteoporosis result from the disruption of the bone remodeling process and can place an individual at a serious fracture risk. Bone remodeling is the complex process by which old bone is replaced with new tissue. This process occurs continuously in the body and is carried out by bone cells that are regulated by numerous metabolic and mechanical factors. The remodeling process provides for various functions such as adaptation to mechanical loading, damage repair,
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Takai, Erica, Clark T. Hung, Aurea Tucay, et al. "Design of a Microfluidic System for 3D Culture of Osteocytes In Vitro." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33229.

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Bone adapts to its mechanical environment so that its form follows function, a mechanism known as Wolff’s law, or bone adaptation. Although the basic concepts of Wolff’s law have been generally accepted, the regulatory signals and the underlying cellular and molecular pathways, which mediate this adaptive process, are unknown. Failure of normal bone adaptation plays a significant role in the etiology of metabolic bone diseases such as osteoporosis and osteopetrosis, bone loss in space flight and failure of total joint replacements. During the past three decades, there have been extensive in vi
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Tseng, Wei-Ju, Hainan Zhu, Beom Kang Huh, et al. "Assessment of the Vascular and Trabecular Microstructures Using Micro Computed Tomography, Vascular Network Perfusion, and Image Registration Techniques." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14699.

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Bone is a dynamic organ that constantly undergoes remodeling throughout one’s life. The remodeling process is required to repair damaged bone tissue and more importantly, to regulate calcium and phosphate homeostasis through the osteocytic network in conjunction with the microvascular network within bone marrow. Recently, techniques combining micro computed tomography (μCT) imaging with vascular network perfusion were developed to allow for 3-D visualization of the bone vascular network structure [1]. However, simultaneous visualization of the trabecular and vascular microstructures using stan
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Holdstein, Y., and A. Fischer. "Modeling Micro-Scaffold-Based Implants for Bone Tissue Engineering." In ASME 2008 9th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2008. http://dx.doi.org/10.1115/esda2008-59034.

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Metabolic bone diseases are at the forefront of scientific and biomedical research worldwide. Diseases such as osteoporosis are characterized by increased bone fragility, which leads to micro-architectural deterioration of bone tissue and eventually to micro fractures. At the micro-structural level, bone is constructed from thin rods known as trabeculae and plates. These rods and plates are arranged in semi-regular, three-dimensional patterns and constitute highly anisotropic and heterogenic material. The bone micro-structure is stochastic in nature and varies according to patient, bone type a
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Zahirović, Nedim, Bojan Toholj, Marko Cincović, Ozren Smolec, and Mimi Ristevski. "Lameness in heifers: Integration of biological, metabolic and production characteristics and environmental factors as predisposing for the occurence of lameness." In Zbornik radova 26. medunarodni kongres Mediteranske federacije za zdravlje i produkciju preživara - FeMeSPRum. Poljoprivredni fakultet Novi Sad, 2024. http://dx.doi.org/10.5937/femesprumns24040z.

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The importance of lameness in heifers has been recognized more and more recently, so the thesis that "lameness in cows is a disease that starts in heifers" has been presented. In his work, he states that the occurrence of chromosotis in heifers predisposes them later to more frequent occurrence of acropodium diseases that can lead to lameness. Early detection of lameness, or even better, early detection of predisposing factors in heifers, could be of great importance in better understanding the problem of lameness in cattle. The corium of the hoof that is damaged by some disease loses its prim
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Yadykina, T. K., N. N. Mikhailova, and A. G. Zhukova. "BIOMEDICAL ASPECTS OF THE FORMATION OF METABOLIC MALADAPTATION IN CHRONIC OCCUPATIONAL INTOXICATION WITH FLUORIDE COMPOUNDS." In The 17th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2023). FSBSI «IRIOH», 2023. http://dx.doi.org/10.31089/978-5-6042929-1-4-2023-1-535-539.

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Long-term exposure to fluorides on the body of aluminum production workers is a determining factor in the development of chronic occupational intoxication with fluorine compounds, the pathogenetic mechanisms of which have not been studied enough. The systemic aspects of its course remain open. The aim — on the basis of experimental and clinical genetic data to study the medical and biological aspects of the formation of metabolic maladaptation in the dynamics of fluoride intoxication. Material and methods. The study included 370 metallurgists with occupational pathology and a comparison group,
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Lima, Rodrigo Quevedo de, Eimi Nascimento Pacheco, Luiz Henrique Santana de Araujo, Cassio Fernando Paganini, and Katsuki Arima Tiscoski. "PLASMOBLASTIC LYMPHOMA WITH MAMMARY MANIFESTATION: A CASE REPORT." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1085.

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Introduction: Plasmoblastic lymphoma (PBL) is a rare entity of non-Hodking lymphoma that usually occurs in the oral cavity in immunosuppressed patients. The involvement of other organs has rarely been reported. The breast can be the site of the initial manifestation of many diseases and in cases like this report, lymphomas should be considered as differential diagnoses. Case report: D.S., female, 28 years old, quality reviewer, married, two children. Carrier of human immunodeficiency virus (HIV) with recent treatment. Intern for investigation of liver, duodenal and breast abnormalities. She ha
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Delipovici, Irina, and Inga Deleu. "The importance of the vitamin d and its effects on the human organism." In The International Scientific Congress "Sports. Olimpysm. Health". SOH 2023. 8th Edition. The State University of Physical Education and Sport, 2025. https://doi.org/10.52449/soh23.16.

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The human body needs a variety of nutrients, for a normal fucntionality, and a major one of them is the fat-soluble Vitamin D. This vitamin can be found in several forms, but the most important for human body is Vitamin D2 and D3. The D2 form, named ergocalciferol, is produced by plants and mushrooms. It is also spread in different types of grains - rye, oat, wheat, barley. The Vitamin D3 ("The vitamin of the sun"), also named - cholecalciferol, of animal origin, is synthesized by the organism in 80-90% proportions. It is due to the contact of the B ultraviolet rays and the specific receptors
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