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Artykuły w czasopismach na temat "Brain Tonic"

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Del Vecchio, Maria, Carlotta Fossataro, Flavia Maria Zauli, et al. "Tonic somatosensory responses and deficits of tactile awareness converge in the parietal operculum." Brain 144, no. 12 (2021): 3779–87. http://dx.doi.org/10.1093/brain/awab384.

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Abstract Although clinical neuroscience and the neuroscience of consciousness have long sought mechanistic explanations of tactile-awareness disorders, mechanistic insights are rare, mainly because of the difficulty of depicting the fine-grained neural dynamics underlying somatosensory processes. Here, we combined the stereo-EEG responses to somatosensory stimulation with the lesion mapping of patients with a tactile-awareness disorder, namely tactile extinction. Whereas stereo-EEG responses present different temporal patterns, including early/phasic and long-lasting/tonic activities, tactile-
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Scimemi, Annalisa, Anna Andersson, Joost H. Heeroma, et al. "Tonic GABAAreceptor-mediated currents in human brain." European Journal of Neuroscience 24, no. 4 (2006): 1157–60. http://dx.doi.org/10.1111/j.1460-9568.2006.04989.x.

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Kantode, Dipti* Kavitake Dhiraj. "Kaempferol's pharmacological effects on strychnine-induced convulsions in lab mice (Albino mice)." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 1543–54. https://doi.org/10.5281/zenodo.14409093.

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Historical background of epilepsy The word epilepsy is derived from Greek word Epilambane in and means to seizure upon or to taking hold of or to take over. Epilepsy is a chronic neurological disorder, with a prevalence of about 1%, which is characterized by the recurrent appearance of spontaneous seizures due to neuronal hyperactivity in the brain (Dell;1986) Whitman S, 01  Definition of epilepsy Epilepsy is a chronic neurological disorder, with a prevalence of about 1%, which is characterized by the recurrent appearance of spontaneous seizures due to neuronal hyperactivity in the brain
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He, Xiaosong, Ganne Chaitanya, Burcu Asma, et al. "Disrupted basal ganglia–thalamocortical loops in focal to bilateral tonic-clonic seizures." Brain 143, no. 1 (2019): 175–90. http://dx.doi.org/10.1093/brain/awz361.

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Abstract Focal to bilateral tonic-clonic seizures are associated with lower quality of life, higher risk of seizure-related injuries, increased chance of sudden unexpected death, and unfavourable treatment outcomes. Achieving greater understanding of their underlying circuitry offers better opportunity to control these seizures. Towards this goal, we provide a network science perspective of the interactive pathways among basal ganglia, thalamus and cortex, to explore the imprinting of secondary seizure generalization on the mesoscale brain network in temporal lobe epilepsy. Specifically, we pa
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Bhavani J and Ravichandran S. "Underlying antioxidant activity in the anticonvulsant potency of polyherbal tonic." International Journal of Pharmaceutical Research and Life Sciences 7, no. 2 (2020): 25–29. http://dx.doi.org/10.26452/ijprls.v7i2.1219.

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Convulsions are the commonest of the symptoms that prevail in the most of the diseases that affect the human nervous system. Almost 1% of the world’s population now suffer from epilepsy as a long-term disease and had been on medication for an extended period of time. There are many investigations and theories advocating that the elevated enzyme activity in the brain and their inability to protect the brain from the free radical generation and normalization will lead to convulsions and seizures. There were investigations that the free radicals were counter acted by the protective enzymes in the
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Varghese, G. I., M. J. Purcaro, J. E. Motelow, et al. "Clinical use of ictal SPECT in secondarily generalized tonic–clonic seizures." Brain 132, no. 8 (2009): 2102–13. http://dx.doi.org/10.1093/brain/awp027.

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Blumenfeld, H., G. I. Varghese, M. J. Purcaro, et al. "Cortical and subcortical networks in human secondarily generalized tonic–clonic seizures." Brain 132, no. 4 (2009): 999–1012. http://dx.doi.org/10.1093/brain/awp028.

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Sirigu, Angela, and Michel Desmurget. "Somatosensory awareness in the parietal operculum." Brain 144, no. 12 (2021): 3558–60. http://dx.doi.org/10.1093/brain/awab415.

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Li, Zhongxia, Jiangping Wang, Huimin Yu, and Kewen Jiang. "Opening of KATP Channel Regulates Tonic Currents From Pyramidal Neurons in Rat Brain." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 44, no. 6 (2017): 718–25. http://dx.doi.org/10.1017/cjn.2016.455.

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AbstractBackground: ATP-sensitive K+ (KATP) channels couple metabolic state to cellular excitability. Activation of neuronal and astrocytic mitochondrial KATP (mitoKATP) channels regulates a variety of neuronal functions. However, less is known about the impact of mitoKATP on tonic γ-aminobutyric acid (GABA) inhibition. Tonic GABA inhibition is mediated by the binding of ambient GABA on extrasynaptic GABA A-type receptors (GABAARs) and is involved in regulating neuronal excitability. Methods: We determined the impact of activation of KATP channels with diazoxide (DIZ) on tonic inhibition and r
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Spampanato, Jay, Anne Gibson, and F. Edward Dudek. "The antihelminthic moxidectin enhances tonic GABA currents in rodent hippocampal pyramidal neurons." Journal of Neurophysiology 119, no. 5 (2018): 1693–98. http://dx.doi.org/10.1152/jn.00587.2017.

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Macrocyclic lactones (MLs) are commonly used treatments for parasitic worm and insect infections in humans, livestock, and companion animals. MLs target the invertebrate glutamate-activated chloride channel that is not present in vertebrates. MLs are not entirely inert in vertebrates, though; they have been reported to have activity in heterologous expression systems consisting of ligand-gated ion channels that are present in the mammalian central nervous system (CNS). However, these compounds are typically not able to reach significant concentrations in the CNS because of the activity of the
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Rozprawy doktorskie na temat "Brain Tonic"

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Ridd, Michael J. "Toxic effects of kainic acid upon dopaminergic and opioid systems in rat brain." Thesis, University of Surrey, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336994.

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Pagaria, Roberto. "Cohomology and combinatorics of toric arrangements." Doctoral thesis, Scuola Normale Superiore, 2019. http://hdl.handle.net/11384/85733.

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This Ph.D. thesis presents my results obtained in the last three years. These results have appeared in the following preprints and articles: [Pag19b, Pag19d, CDD+18, Pag18a, Pag18c, Pag19c, Pag18b, Pag19a, PP19b]. Initially, I investigated toric arrangements, a type of arrangements inspired by the hyperplane ones. Toric arrangements have been studied intensively in the last fifteen years both from topological and from combinatorial point of view. My results describe the cohomology ring of toric arrangements and their dependency from the combinatorial data. Later I have worked on another t
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Munder, Tonia [Verfasser]. "Investigation of early histopathological changes in rodent models of Alzheimer's Disease, Parkinson's Disease and CADASIL : brain magnet resonance elastography for early disease detection and staging correlated to histopathology and analysis of neurogenesis and cell survival / Tonia Munder." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2018. http://d-nb.info/1160514887/34.

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Munder, Tonia Laura [Verfasser]. "Investigation of early histopathological changes in rodent models of Alzheimer's Disease, Parkinson's Disease and CADASIL : brain magnet resonance elastography for early disease detection and staging correlated to histopathology and analysis of neurogenesis and cell survival / Tonia Munder." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2018. http://d-nb.info/1160514887/34.

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Najberg, Mathie. "Development, physico-chemical characterization and biological evaluation of silk fibroin/hyaluronic acid freeze-dried sponges for the trapping of Glioblastoma cells Reversing the tumor target: Establishment of a tumor trap Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release". Thesis, Angers, 2019. http://www.theses.fr/2019ANGE0040.

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Le glioblastome (GBM) est une tumeur dévastatrice du système nerveux central. Malgré un traitement agressif, les récidives sont inévitables et l'application d'une stratégie thérapeutique efficace demeure un défi. Le concept révolutionnaire de piège à cellules cancéreuses peut offrir de nouvelles opportunités. L'objectif est d'attirer et de confiner les cellules cancéreuses résiduelles entourant la cavité chirurgicale dans un implant polymère biomimétique délivrant des molécules chimio attractantes. Le SDF-1α, également appelé CXCL12, se lie sélectivement au récepteur CXCR4 à la surface des cel
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Huang, Chih-Sheng, and 黃志勝. "Assessing brain effective connectivity from tonic and phasic EEG dynamics." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/a54tkd.

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博士<br>國立交通大學<br>電控工程研究所<br>104<br>Effective connectivity, which is commonly used in the study of causal relationships, refers to relationships or dependences among neuronal activities in distant brain regions. Granger causality (GC) is a property that is frequently used to estimate effective connectivity. However, GC is limited by inherent assumptions that may lead to incorrect results. Transfer entropy (TE), which is based on information theory, is an alternative metric of effective connectivity. TE is nonlinear and not dependent on a specific model of interaction. GC is a special case of TE
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Hashmi, Javeria Ali. "Temporal Dynamics of Heat Pain Sensations." Thesis, 2010. http://hdl.handle.net/1807/24767.

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The moment-to-moment fluctuations in pain-evoked sensory and emotional qualities, and how the pain experience differs between sexes are not well understood. Therefore, this thesis sought to 1) characterise the temporal profiles of the most prominent noxious heat-evoked sensations, 2) characterise sex differences in these sensations, 3) evaluate the magnitude of sharp pain quality evoked in hairy and glabrous skin, and 4) determine the role of absolute stimulus temperatures on sex differences in pain adaptation and habituation. A broad-based heat pain model was developed for this study that inc
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Książki na temat "Brain Tonic"

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Norden, Michael J. Beyond prozac: Brain-toxic lifestyles, natural antidotes & new generation antidepressants. ReganBooks, 1995.

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Norden, Michael J. Beyond prozac: Brain-toxic lifestyles, natural antidotes & new generation antidepressants. ReganBooks, 1995.

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Leaf, Caroline. Who switched off my brain?: Controlling toxic thoughts and emotions. Switch On Your Brain, 2007.

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Morton, Walker, ed. Toxic metal syndrome. Avery Pub. Group, 1995.

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Hertzman, Marc. Clinical trials in psychopharmacology: A better brain. 2nd ed. Wiley-Blackwell, 2010.

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Baorto, David M. Induction and growth of astrocyte processes. Columbia University, 1992.

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Wright, Dick. If he only had a brain--. Pelican Pub., 1998.

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1955-, Kelly Jerry, and Grolier Club, eds. Printing and the brain of man: The sixteenth-century brain : an exhibition and catalogue of selections from the collection of Eugene S. Flamm. The Grolier Club, 2011.

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S, Hecht Jeffrey, and Calub Connie J, eds. Educating families of the head injured: A guide to medical, cognitive, and social issues. Aspen Publishers, 1991.

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Friedman, Diane Broadbent. A matter of life and death: The brain revealed by the mind of Michael Powell. AuthorHouse, 2008.

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Części książek na temat "Brain Tonic"

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Hopf, H. C. "Persistent Tonic Facial Contraction: A Local Brain-Stem Sign." In Brain-Stem Localization and Function. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78172-8_27.

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Beyer, Lothar, Thomas Weiss, Ellen Hansen, and Reinhard Rost. "Phasic and Tonic Changes of the Mean Alpha Frequency (MAF) of the EEG during Motor Performance." In Slow Potential Changes in the Brain. Birkhäuser Boston, 1993. http://dx.doi.org/10.1007/978-1-4757-1379-4_25.

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Reis, Donald J. "Brain Stem Mechanisms Regulating the Tonic and Reflex Control of Blood Pressure." In Topics in the Neurosciences. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2315-0_7.

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Ma, Lianfang, Jianhui Chen, and Ning Zhong. "An Image-Enhanced Topic Modeling Method for Neuroimaging Literature." In Brain Informatics. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-86993-9_28.

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Judy, K. D., G. B. Bulkley, B. E. Hedlund, and Donlin M. Long. "Proposed Toxic Oxidant Inhibitors Fail to Reduce Brain Edema." In Brain Edema IX. Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9334-1_23.

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He, Xiaobo, Ning Zhong, and Jianhui Chen. "Weighted-LDA-TVM: Using a Weighted Topic Vector Model for Measuring Short Text Similarity." In Brain Informatics. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-37078-7_21.

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Wilkinson, Dee. "How our brain can help us." In Creating Your Future After a Toxic Relationship. Routledge, 2021. http://dx.doi.org/10.4324/9781003172734-2.

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Müller, Norbert. "Psychoneuroimmunology in Pula: A Hot Topic with a Long Past." In Mind, Brain and Education. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-33013-1_15.

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Capizzano, Aristides A., Toshio Moritani, Yang Mao-Draayer, Brian Chang, and Deema Fattal. "Toxic and Metabolic Diseases." In Diffusion-Weighted MR Imaging of the Brain, Head and Neck, and Spine. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-62120-9_15.

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Ekici, Faysal, and Salih Hattapoglu. "Differences in Adult and Pediatric Brain Tumors." In The Radiology of Cancer. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359364.3.

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Brain tumors can appear differently in children and adults. The most common CNS tumors in two different age groups should be recognized. Pediatric brain tumors will be specifically addressed in the pediatric radiology section, and in this chapter, the most common pediatric brain tumors will be highlighted with examples to reinforce the topic of adult brain tumors discussed in the previous article.
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Streszczenia konferencji na temat "Brain Tonic"

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Marques, Maria Francisca, Marta Paz, and Tiago Ribeiro. "NEUROMYTHS AND COGNITIVE HEALTH: A STUDY WITH SENIOR CITIZENS." In 11th SWS International Scientific Conferences on SOCIAL SCIENCES - ISCSS 2024. SGEM WORLD SCIENCE, 2024. https://doi.org/10.35603/sws.iscss.2024/s08/61.

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Neuroscience has witnessed profound scientific and technological advancements over recent decades, transforming our understanding of the brain and leading to significant improvements in both diagnosing and treating neurological disorders. This field of knowledge is an exciting topic for researchers and health professionals, psychologists, educators, and even the general public. The rapid expansion and the complexities of neurosciences have also led to the emergence and spread of several neuromyths. These myths concern various misconceptions or unfounded beliefs arising from incorrect interpret
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Posada-Quintero, Hugo F., and Ki H. Chon. "Phasic Component of Electrodermal Activity is more Correlated to Brain Activity than Tonic Component." In 2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI). IEEE, 2019. http://dx.doi.org/10.1109/bhi.2019.8834567.

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Lima, Márcio Pinheiro, Rafael Tuzino Leite Neves Maffei, Pedro Henrique Almeida Fraiman, et al. "Super-refractory status epilepticus after intoxication by quetiapine and carbamate." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.584.

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Introduction: Quetiapine, an atypical antipsychotic, works through the agonism of multiple brain receptors, including dopaminergic, serotonergic, and adrenergic receptors. Compared to typical antipsychotics, quetiapine has a more favorable profile of adverse reactions. Myoclonus is infrequent. However, there have been reports of quetiapine overdose associated with generalized myoclonus. Electroencephalogram (EEG) modifications linked to the use of quetiapine are unusual. Aldicarb, commonly known as ‘chumbinho’ in Brazil, is a carbamate used as a rodenticide. Its toxicity is caused by the inhib
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Maffei, Rafael Tuzino Leite Neves, Daniel Natalio Gauss Yankelevich, Maria Carolina Soares, Leonardo de Sousa Bernardes, Bruna Gutierres Gambirasio, and Adrialdo José Santos. "Multiple cerebral ring enhancing lesions: an atypical finding of high-grade glioma." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.508.

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Introduction: High-grade gliomas are primary neoplasms of the central nervous system and can have multiple clinical and neuroimaging presentations. An unusual radiologic image can lead to diagnostic difficulty, and cancer treatment delay. In rare cases, primary brain tumor can mimic multiple abscesses in magnetic resoanance imaging (MRI). The aim of this paper is to describe a diagnostic challenge in MRI imaging of brain tumors. Case Report based on a retrospective analysis of the medical records of the patient. Case report: This case report describes a previously healthy 48-year-old male eval
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Dunga, Lucas Medeiros, Renner Cassio Nunes de Lucena, Matheus Araújo de Medeiros, et al. "Cerebral tuberculoma as a differential diagnosis for extraaxial lesions in immunocompetent patient: case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.630.

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Introduction: Cerebral tuberculomas are a rare and serious form of tuberculosis, representing 0.2% of intracranial expansive processes. In the absence of conclusive diagnostic tests, doctors often make treatment decisions based on clinical judgment, cerebrospinal fluid (CSF) profile, and radiological findings. Magnetic resonance imaging (MRI) commonly shows discrete lesions with ring enhancement, with perilesional edema, being a relevant differential diagnosis in ring lesions, as their clinical and imaging can mimic brain tumors. The aim to report a case of cerebral tuberculoma in an immunocom
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Montano, Saul Didmar Alquez, and José Marcos Vieira de Albuquerque Filho. "CD8 encephalitis in an HIVinfected patient undergoing regular antiretroviral therapy: a case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.650.

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CD8 + encephalitis, and a destructive complication of HIV, that produces severe brain damage, described in patients regularly using antiretroviral therapy. It arises by viral propagation in mononuclear phagocytes leads to persistent activation of CD8 + lymphocytes. It produces demyelinating lesions, brain infiltration by CD8 + lymphocytes, and vessel hyalinization. Magnetic resonance imaging is characterized by a large area of demyelination with a mass effect and enhancement of the ring in the image. In spite of being a potentially fatal picture, it has treatment. Case report: female patient,
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Pimenta, Marina Luiza, Jessica Andrade de Oliveira, Herval Ribeiro Soares Neto, Sonia Maria Cesar de Azevedo Silva, and Luiza Ferrari de Castro Melo. "Atypical presentation of tacrolimus encephalopathy in a kidney transplant patient." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.452.

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Context: Neurological complications triggered by tacrolimus in transplant patients can occur in a common way. Tacrolimus encephalopathy is a rare presentation. The present case follows atypical patterns of this disease, since it presented as aphasia, seizure and unusual radiological findings. Case report: A 52--year--old female patient complaining of severe headache for 3 days, associated with difficulty in formulating phrases and confusion. She had a history of nephrolithiasis, kidney transplantation (2020), hypertension and diabetes, using tacrolimus, mycophenolate and prednisone. In the hos
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Rocha, Isadora Souza, Paola Nabhan Leonel dos Santos, João Guilherme Bochnia Küster, et al. "Pelizaeus-Merzbacher Disease with Novel Variant: Case Report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.672.

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Context: Pelizaeus-Merzbacher Disease (PMD) is a rare X-linked recessive hypomyelinating leukodystrophy caused by mutations in the proteolipid protein 1 (PLP1) gene, associated with myelin sheath development and stability. The result is a broad spectrum of clinical phenotypes. Diagnosis is confirmed by genetic testing. Clinical features include hypotonia followed by progressive spasticity, nystagmus, ataxia and cognitive impairment. Males are more affected. Females are asymptomatic or present milder symptoms. Most cases arise from duplications, point and null mutations. Null mutations are asso
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Iegoroff, Renan, Rafael Herlan Terceros Vaca, Gustavo Araújo Pinheiro, Alvaro Marcelo Huchani Huanca, Matheus Henrique de Souza Coradini, and Leonardo Mariano Inácio Medeiros. "Cadasil, atypical and familial presentation – family case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.318.

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Introduction: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is a non-atherosclerotic, nonamyloid, hereditary cerebral disease of small vessels and capillaries caused by mutations in the NOTCH-3 gene located on chromosome 19. The presence of granular osmophilic material (GOM) deposition in the smooth muscle cells of vessel walls is the pathological hallmark of arteriopathy in CADASIL. GOM deposits in the basal lamina of smooth muscle of small vessels are pathognomonic for CADASIL. The presence of GOM in capillary blood vessels of the skin
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Mendes, Larissa Braga, Gabriel Pinheiro Martins de Almeida e. Souza, Marianna Pinheiro Moraes de Moraes, José Luiz Pedroso, and Orlando Graziani Povoas Barsottini. "Hypertrophic pachymeningitis associated with systemic lupus erythematosus: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.764.

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Introduction: Hypertrophic pachymeningitis is a chronic inflammatory process that results in focal or diffuse thickening of the dura mater. Nowadays, it’s an uncommon cause of neurological symptoms and has been mainly associated with infections, inflammatory diseases and carcinomatosis. This is a report of a single case based on retrospective analysis of the patient’s medical records. Case report: A 48-year-old woman was admitted in the emergency department with a two-month history of severe headaches that worsened with neck flexion and four episodes of focal to bilateral tonic-clonic seizures
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Raporty organizacyjne na temat "Brain Tonic"

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Sick, Thomas J. Pro-Apoptotic Changes in Brain Mitochondria After Toxic Exposure. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada397717.

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Raychev, Nikolay. Can human thoughts be encoded, decoded and manipulated to achieve symbiosis of the brain and the machine. Web of Open Science, 2020. http://dx.doi.org/10.37686/nsrl.v1i2.76.

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This article discusses the current state of neurointerface technologies, not limited to deep electrode approaches. There are new heuristic ideas for creating a fast and broadband channel from the brain to artificial intelligence. One of the ideas is not to decipher the natural codes of nerve cells, but to create conditions for the development of a new language for communication between the human brain and artificial intelligence tools. Theoretically, this is possible if the brain "feels" that by changing the activity of nerve cells that communicate with the computer, it is possible to "achieve
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Breinbauer, Cecilia, and Stanley Greenspan. Early Social-Emotional and Cognitive Basis for Human Development Potential, and Improved Quality of Life. Inter-American Development Bank, 2007. http://dx.doi.org/10.18235/0006819.

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This presentation discusses the effects of social motivation on brain development in early childhood and the role of emotions on child development. Optimal nutrition and social-emotional development are the basic building blocks for higher level thinking abilities, human development and quality of life. The authors examine how to develop internationally comparable and feasible measures of child development. Then it will be possible to gather evidence to inform policy makers of the need for specific country policies and programs on this topic. This presentation was prepared for the IDB-PAHO Con
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Bacharach, Eran, W. Ian Lipkin, and Avigdor Eldar. Identification of the etiological agent of tilapia disease in the Lake of Galillee. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7597932.bard.

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Background to the topic. Tilapines serve as the second most important group of farmed fish worldwide. Massive mortality of wild and cultured tilapia has been observed recently in Israel but the pathogen of this disease has not been identified. We proposed to identify the agent responsible for disease.  Major conclusions, solutions, achievements. We characterized the lesions in diseased fish and found that the brain was one of the affected organs. We found conditions to isolate from brains of diseased fish the etiological agent of the tilapia disease and to propagate it in cell culture. This l
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Rumbaut Gil, Ana Laura. A Systemic Analysis of Vascular Dysfunction in Parkinson’s Disease: Reviewing the Roles of Astrocytes and COX-2. Florida International University, 2025. https://doi.org/10.25148/fiuurj.3.1.6.

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Although Parkinson’s Disease (PD) is the second most prevalent neurodegenerative disease in the U.S., the pathology remains an enigma. Many neuroinflammation hypotheses have been studied to explain its development. It’s shown that inflammatory markers such as COX-2 activity, which synthesizes the potent vasodilator PGE2, are overexpressed in PD. Additionally, astrocytes, regulators of inflammation in the brain and BBB, undergo important changes during PD. However, the vascular consequences that all this has for PD-led neurodegeneration are relatively unexplored. We conducted a systemic review
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Bloch, Guy, Gene E. Robinson, and Mark Band. Functional genomics of reproduction and division of labor in a key non-Apis pollinator. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7699867.bard.

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i. List the original objectives, as defined in the approved proposal, and any revisions made at the beginning or during the course of project. Our objectives were: 1) develop state-of-the-art functional genomics tools for B. terrestris. These resources will be then used to: 2) characterize genes and molecular pathways that are associated with reproduction, 3) characterize genes and molecular pathways associated with specialization in foraging or nursing activities, and 4) determine the extent to which juvenile hormone (JH) is involved in the regulation of reproduction and division of labor. 5)
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